Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.9;kidney: 133.3;liver: 345.6;pancreas: 138.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 268.2;Inhibitory neurons: 95.0;Oligodendrocyte precursor cells: 76.9;Proximal tubular cells: 94.9" "Cancer enhanced" "Detected in all" "glioma: 27.3;liver cancer: 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 127.5;MCF7: 81.9;RH-30: 67.4;T-47d: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favorable (5.36e-5)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favorable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 3.3 27.7 94.6 4.7 105.4 2.2 5.1 85.2 103.4 3.8 70.7 7.6 43.6 3.8 9.6 7.7 6.2 4.4 14.1 90.2 120.7 133.3 345.6 4.5 5.0 90.8 107.4 10.5 138.3 8.2 55.8 3.4 137.6 21.7 7.8 29.6 6.5 3.5 1.6 2.7 20.1 2.7 88.1 4.1 7.4 13.4 137.9 4.2 29.3 1.4 5.9 9.9 4.1 70.9 0.7 0.2 32.1 18.7 5.0 1.7 2.0 4.2 2.2 1.8 0.7 12.7 0.9 4.0 1.4 2.3 1.2 8.3 2.1 7.7 2.4 2.3 2.1 5.5 0.1 127.5 8.1 1.3 8.3 6.5 3.4 3.2 1.4 0.9 0.6 10.7 1.1 2.6 0.6 81.9 2.1 0.6 2.8 23.2 0.3 9.7 67.4 1.8 1.2 20.9 5.1 15.7 1.9 1.0 0.2 6.2 42.6 3.4 0.6 0.8 5.7 2.7 0.1 3.0 0.3 0.8 0.8 5.7 4.2 0.7 1.9 2.7 1.5 2.2 0.7 0.6 1.0 1.1 1.2 1.2 0.7 1.1 6.1 1.2 4.2 0.2 1.1 1.2 94.6 105.4 85.2 103.4 90.2 120.7 90.8 107.4 137.6 88.1 137.9 70.9 1.7 0.0 6.9 39.5 6.1 1.5 4.0 3.3 2.2 27.3 9.1 5.0 10.8 20.0 5.8 1.8 4.2 1.4 5.3 8.9 23.5 1.6 13.0 12.9 6.2 2.4 15.6 13.9 41.8 6.2 1.5 3.2 5.6 12.9 1.3 59.5 7.1 268.2 5.2 35.3 95.0 3.9 2.0 15.7 7.4 8.7 3.7 8.2 1.8 19.7 6.5 48.6 9.2 76.9 17.7 6.8 6.1 4.5 1.0 7.4 15.7 94.9 3.6 5.8 0.0 4.3 3.8 3.7 0.9 9.5 0.6 1.4 6.3 2.3 6.9 5.0 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.8;Distal enterocytes: 109.9;Microglial cells: 570.6;Paneth cells: 106.2;Proximal enterocytes: 204.6" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cell line enhanced" "Detected in some" "CACO-2: 67.3;HEK 293: 20.4;HEL: 37.7;Hep G2: 18.5;RPTEC TERT1: 24.2;SH-SY5Y: 78.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 101.7 14.1 3.9 13.6 1.9 3.6 13.7 17.6 6.4 5.3 16.6 26.4 11.0 3.6 3.1 5.0 15.5 1.9 15.3 15.6 33.7 28.0 6.4 3.2 17.6 14.4 2.2 2.0 1.4 0.5 2.3 19.7 4.2 18.2 2.2 1.2 3.1 0.2 1.5 70.7 9.8 15.1 4.2 2.1 0.9 19.3 2.7 1.9 1.4 3.5 3.6 1.7 14.3 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 20.4 37.7 4.2 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 24.2 0.2 0.9 78.9 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 4.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 11.1 0.0 27.2 0.8 2.7 6.8 0.0 2.5 1.7 6.6 0.2 17.9 0.0 0.1 0.0 2.5 14.1 13.6 13.7 17.6 15.3 15.6 17.6 14.4 19.7 15.1 19.3 14.3 17.1 0.0 3.0 3.9 9.9 0.8 0.1 0.0 1.2 1.9 0.4 3.9 3.0 95.8 0.6 49.7 0.0 5.8 24.7 109.9 5.9 13.8 27.3 0.6 0.6 52.9 0.0 7.8 16.1 1.9 0.2 3.7 0.0 0.7 3.8 0.3 2.5 38.4 0.4 0.0 11.4 15.8 0.0 0.6 1.2 3.8 0.9 1.6 0.0 570.6 0.2 0.2 32.0 6.0 3.2 8.1 106.2 0.0 4.6 0.2 204.6 57.7 0.7 1.1 0.0 0.4 1.3 0.4 0.9 0.2 0.6 9.9 24.5 0.1 19.9 0.3 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 41.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 51.3;granulocytes: 53.9;Microglial cells: 203.3" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 245.7;HMC-1: 256.3;RPTEC TERT1: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" 2.2 1.3 2.5 6.1 2.3 4.1 6.9 2.5 2.5 4.9 7.2 9.2 4.9 3.4 18.8 2.0 10.2 6.1 2.0 2.3 5.4 18.0 1.3 7.6 3.9 4.3 3.7 3.7 3.3 22.5 1.4 2.1 4.6 41.1 8.5 0.9 1.5 5.5 5.3 2.9 5.4 6.3 4.9 4.1 5.2 4.7 3.2 3.9 7.7 1.7 6.3 15.4 1.8 5.1 18.5 31.7 5.3 9.4 9.5 12.3 1.3 14.4 14.3 12.6 10.9 43.8 13.2 10.2 9.3 19.5 9.0 24.0 7.9 7.1 15.8 30.7 12.1 245.7 8.8 8.8 19.2 28.6 256.3 9.4 3.2 9.1 18.5 17.9 16.4 11.3 25.8 0.4 17.1 5.9 5.4 4.6 6.2 22.3 7.9 7.7 14.3 26.9 69.3 40.4 12.5 9.3 4.8 1.2 10.1 5.9 0.0 15.1 27.0 13.3 8.6 11.2 17.3 0.1 0.0 4.0 25.4 16.0 6.6 0.2 0.5 0.2 1.3 0.6 1.1 1.4 1.0 1.5 1.8 1.6 0.6 1.5 0.3 1.9 2.3 0.3 1.5 1.3 2.5 2.3 2.5 2.5 2.3 5.4 4.3 3.7 4.6 4.9 3.2 5.1 4.6 9.6 32.7 28.4 5.8 4.2 7.0 7.3 4.0 0.1 0.6 0.6 4.5 8.6 9.1 23.9 22.9 0.1 2.0 2.7 0.0 6.9 3.8 4.2 11.3 19.8 0.0 51.3 13.6 3.1 0.4 5.7 6.1 6.0 53.9 9.5 2.9 0.6 4.5 0.0 10.3 4.0 0.0 2.5 8.1 2.0 6.8 10.7 1.8 203.3 13.5 0.5 4.1 16.1 2.5 2.9 8.3 1.9 8.3 27.1 0.5 26.4 4.7 0.8 0.0 8.2 3.1 0.9 8.3 3.4 7.5 0.3 6.4 17.3 9.2 4.5 ABHD11 "PP1226, WBSCR21" ENSG00000106077 "Abhydrolase domain containing 11" Q8NFV4 7 73736094-73738867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Urothelial cells: 241.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 92.6;SK-BR-3: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024042, HPA049641" Approved Supported Mitochondria NA NA 31000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA024042: AB_1844445, HPA049641: AB_2680838" "unprognostic (4.74e-2)" "unprognostic (8.62e-3)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-3)" "unprognostic (1.91e-2)" "unprognostic (9.32e-2)" "unprognostic (7.79e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.66e-7)" "unprognostic (3.61e-3)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (7.29e-2)" 7.5 13.5 9.3 5.6 9.8 4.5 12.2 10.6 11.3 9.3 16.4 31.3 15.9 7.2 5.8 13.6 13.8 8.6 21.6 9.1 9.9 29.4 9.5 9.5 4.0 11.4 11.1 3.9 25.7 12.9 16.4 7.6 11.0 23.2 17.4 3.0 21.3 8.2 11.3 13.3 19.8 3.5 10.4 8.1 9.0 7.2 12.3 3.3 28.1 10.3 5.4 8.5 6.9 10.4 46.9 10.7 7.1 16.4 3.7 5.0 39.7 21.1 8.9 12.7 14.9 13.1 51.4 22.2 6.2 9.0 17.3 20.2 3.2 12.1 8.8 8.2 15.4 10.8 6.7 8.3 6.5 11.8 11.4 4.6 5.0 16.4 7.6 4.6 9.2 7.4 15.1 11.8 12.0 92.6 9.2 14.9 8.3 29.5 39.1 5.0 11.4 41.0 29.7 21.8 18.3 7.6 17.1 113.0 7.1 5.1 36.8 7.8 9.1 10.8 10.2 46.5 22.2 7.3 4.2 14.8 17.3 11.2 20.3 10.2 19.1 19.3 8.2 32.7 6.8 10.1 9.1 8.7 19.4 12.7 8.4 5.9 15.2 14.9 33.5 9.2 6.3 11.9 9.3 9.8 10.6 11.3 9.1 9.9 11.4 11.1 11.0 10.4 12.3 10.4 7.9 44.8 15.7 3.3 10.6 5.5 60.3 39.8 10.2 16.6 43.1 21.7 16.9 54.3 60.7 57.0 4.2 86.3 8.7 156.9 72.4 52.1 1.2 98.9 17.3 9.7 62.6 9.4 5.8 40.8 120.1 9.9 35.7 98.1 15.2 6.3 4.6 8.7 28.0 5.0 4.0 106.8 95.6 11.3 10.5 2.3 9.0 13.7 14.2 4.7 10.4 26.6 14.4 3.0 3.7 38.2 151.7 3.4 10.5 53.1 128.2 55.3 127.6 15.2 0.0 10.3 14.4 6.8 7.1 23.3 6.3 127.7 9.6 22.1 128.9 241.3 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 197.6;Cardiomyocytes: 61.7;Hepatocytes: 116.0;Oligodendrocyte precursor cells: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 75.3;HHSteC: 77.6;HSkMC: 89.4;hTERT-HME1: 90.9;hTERT-RPE1: 76.2;TIME: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" 68.4 7.4 19.2 3.8 18.0 0.5 57.6 49.7 19.1 12.5 6.8 11.1 2.7 10.4 6.3 33.2 14.4 7.1 87.8 20.4 26.7 19.8 115.8 20.0 5.3 37.2 25.2 3.9 2.7 59.6 6.8 34.4 28.7 9.1 5.0 28.6 6.5 8.2 45.8 8.3 7.8 10.6 34.0 8.7 5.4 2.0 29.9 2.2 9.2 38.7 4.5 14.1 17.7 30.2 23.6 4.8 0.0 0.2 39.6 75.3 0.1 16.1 44.8 9.1 15.8 0.1 16.2 0.0 2.7 20.5 47.9 0.5 0.1 18.9 17.7 0.1 0.2 0.0 1.4 0.6 77.6 0.0 0.1 89.4 5.1 32.5 90.9 76.2 41.1 0.0 0.0 7.2 54.8 9.2 0.0 0.0 0.2 1.5 63.0 0.0 0.1 0.0 50.3 16.0 6.3 0.1 3.3 1.1 8.7 1.2 1.5 0.1 103.9 18.9 4.2 19.9 27.7 0.1 0.0 0.0 33.5 0.0 55.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 2.7 19.2 18.0 49.7 19.1 20.4 26.7 37.2 25.2 28.7 34.0 29.9 30.2 197.6 0.0 3.7 21.5 1.3 1.5 1.2 2.6 0.6 2.5 7.6 3.9 61.7 18.6 5.3 0.0 0.0 0.2 0.3 0.0 5.9 8.7 3.0 0.5 2.5 39.6 0.0 0.0 31.0 3.5 0.7 9.4 3.6 2.5 1.3 0.0 34.2 116.0 12.3 28.6 33.7 0.0 8.2 13.5 1.1 0.5 0.3 8.5 5.4 21.5 0.9 19.3 0.0 63.8 25.6 22.5 0.0 0.7 0.1 2.5 0.0 23.5 4.9 25.1 0.0 7.4 7.7 1.7 2.7 2.0 1.6 0.4 0.7 0.5 0.0 22.2 AC135068.1 ENSG00000278263 "Novel protein, identical to IGHV4-4" 15 21742364-21742799 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 52.2;lymphoid tissue: 57.9;urinary bladder: 97.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "memory B-cell: 24.0;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 45 "B-cells: 24.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "prognostic favorable (2.52e-4)" "unprognostic (1.05e-1)" "unprognostic (9.75e-3)" "unprognostic (1.80e-2)" "unprognostic (5.51e-6)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-1)" 1.0 0.0 0.2 27.3 0.1 4.2 5.4 0.0 0.0 3.7 0.0 52.2 22.6 0.2 0.0 3.7 0.5 0.5 2.1 0.1 0.0 0.2 1.0 5.5 5.5 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.4 22.1 0.0 30.1 2.1 0.0 1.1 6.0 0.0 0.0 9.4 22.3 0.1 0.0 7.8 0.7 0.0 57.9 97.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.2 0.0 0.0 7.7 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.9 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 231.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 262.1;Early spermatids: 187.0;Exocrine glandular cells: 176.6;Hepatocytes: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 10.9 21.6 22.2 18.5 24.4 22.4 23.6 30.2 30.0 12.8 20.1 38.5 31.2 10.9 40.0 32.6 11.4 10.6 9.4 22.7 27.6 27.0 231.3 20.2 25.0 39.4 26.3 17.3 9.4 12.5 3.2 11.8 39.1 35.6 33.8 19.5 15.5 9.3 4.9 18.1 17.9 15.8 24.8 9.7 19.5 28.6 24.4 39.4 9.0 7.1 36.7 13.7 9.1 28.1 70.1 58.8 451.9 160.8 57.2 111.6 14.4 57.4 70.5 141.8 244.5 234.0 87.1 55.9 29.0 48.7 458.2 64.5 174.8 465.8 166.7 35.2 174.4 127.4 97.2 418.8 62.0 81.4 35.8 62.2 40.1 231.1 92.9 21.4 68.8 160.1 139.9 104.3 85.5 113.0 137.0 154.0 142.8 65.5 41.7 83.9 94.4 173.1 377.2 93.7 107.8 63.2 67.5 43.3 26.2 18.5 83.4 157.3 39.2 50.3 45.7 72.1 154.0 47.7 89.0 142.0 15.7 151.2 77.1 30.1 24.9 46.7 47.9 33.9 47.3 46.6 54.1 47.8 34.7 51.4 53.3 43.2 11.0 41.3 23.6 30.4 79.0 46.2 22.2 24.4 30.2 30.0 22.7 27.6 39.4 26.3 39.1 24.8 24.4 28.1 11.8 12.8 45.4 15.3 25.8 26.1 32.4 262.1 22.2 19.4 33.4 24.5 1.2 42.9 115.5 20.2 2.1 53.7 28.6 34.7 70.5 78.8 187.0 14.3 9.9 18.8 17.2 38.5 14.3 176.6 97.0 21.6 9.7 25.9 13.3 47.7 16.1 214.8 58.1 13.5 14.7 23.6 83.4 14.8 29.8 128.8 13.7 25.7 30.2 1.0 58.9 22.5 30.9 13.0 17.5 65.6 28.8 19.2 25.5 38.7 15.4 50.0 30.1 24.7 0.0 25.1 44.9 28.5 45.6 43.0 21.0 35.2 31.0 102.5 33.0 38.9 ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 88.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Inhibitory neurons: 2.1;Melanocytes: 1.8;Spermatocytes: 1.7;Suprabasal keratinocytes: 5.8" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cell line enhanced" "Detected in single" "T-47d: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" 0.1 0.1 0.1 0.1 0.1 0.1 3.3 0.4 0.2 3.4 0.3 0.0 0.0 0.2 0.2 12.2 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.2 1.7 0.0 0.0 3.2 0.1 0.5 88.1 0.2 0.1 0.0 0.3 0.0 1.1 0.2 1.3 0.0 0.0 0.7 0.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.5 0.0 0.1 0.7 0.7 0.1 0.3 0.0 0.1 0.8 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.1 0.9 1.0 1.8 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.7 1.0 0.0 5.8 0.0 0.4 0.0 0.0 0.1 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866917-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported Nucleoplasm,Cytosol No No 3100000 "Cluster 44: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB007783: AB_562242, HPA022434: AB_1844513, HPA022953: AB_1844514, HPA022959: AB_1844515, HPA028758: AB_10603575" "unprognostic (2.21e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (2.83e-1)" "unprognostic (8.94e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (3.38e-3)" "unprognostic (4.11e-2)" "unprognostic (5.94e-3)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.88e-3)" "unprognostic (1.66e-1)" "unprognostic (9.36e-2)" "unprognostic (3.90e-2)" "unprognostic (4.67e-3)" 64.9 30.2 24.0 43.9 27.2 34.7 46.7 33.6 55.5 33.2 22.5 35.4 49.3 34.4 34.7 30.5 36.0 31.1 27.1 24.7 66.5 47.5 27.5 35.3 42.7 80.3 48.6 21.3 46.3 37.4 22.4 42.4 76.5 62.6 35.7 23.2 39.1 28.5 15.3 28.9 43.7 42.5 34.2 39.1 38.9 32.2 43.1 48.4 30.8 14.9 40.3 36.7 29.2 43.7 127.1 423.2 194.8 168.8 296.1 274.4 178.3 174.0 188.0 213.7 266.3 217.9 141.8 204.7 108.8 245.2 200.6 197.2 253.9 298.0 177.8 184.9 243.0 117.3 228.3 227.5 136.9 191.9 147.1 219.8 88.3 376.9 75.6 140.0 228.7 155.0 147.4 158.5 180.4 130.0 317.8 107.6 127.6 84.8 75.7 205.2 236.2 262.2 221.0 222.4 364.7 200.2 124.5 382.8 133.7 167.6 229.4 181.0 248.4 165.7 135.5 169.0 291.0 91.9 127.0 193.0 280.3 145.7 137.5 32.2 29.2 36.5 30.9 30.9 29.1 21.6 24.4 27.7 33.0 18.3 18.1 20.3 14.6 24.0 39.8 19.1 34.3 33.8 24.0 27.2 33.6 55.5 24.7 66.5 80.3 48.6 76.5 34.2 43.1 43.7 28.2 28.9 26.2 12.4 20.5 25.0 10.0 25.4 12.5 12.1 38.6 21.6 12.6 31.5 21.0 23.9 4.2 22.6 25.9 26.7 11.7 33.8 73.3 31.6 35.3 33.4 65.9 34.3 10.9 33.6 46.5 28.9 23.4 29.2 15.2 28.7 41.4 53.0 31.0 18.5 14.7 54.0 20.3 39.0 25.9 17.5 61.8 27.6 32.0 16.9 42.9 7.6 25.7 11.6 13.6 42.9 16.2 51.1 17.4 35.9 40.4 87.0 31.1 9.4 13.1 17.6 25.7 17.9 36.0 21.6 33.0 22.2 25.1 49.0 22.2 15.5 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ACOXL FLJ11042 ENSG00000153093 "Acyl-CoA oxidase like" Q9NUZ1 2 110732539-111120610 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 7.2;lung: 9.3" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 41.9" "Group enriched" "Detected in some" 6 "lung cancer: 0.6;prostate cancer: 1.1;testis cancer: 2.1;urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 12.1;RPMI-8226: 22.0;RT4: 29.3;U-266/70: 18.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035392, HPA035393" Supported Nucleoli,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol Nucleoli "HPA035392: AB_2674604, HPA035393: AB_2674605" "unprognostic (1.62e-1)" "unprognostic (7.30e-2)" "unprognostic (6.77e-4)" "unprognostic (2.93e-7)" "unprognostic (1.32e-2)" "unprognostic (7.84e-5)" "unprognostic (1.28e-1)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (7.31e-2)" "unprognostic (7.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (2.73e-1)" "unprognostic (1.72e-1)" "prognostic favorable (6.48e-4)" 1.1 0.6 0.4 0.5 0.7 1.5 0.1 0.2 0.4 0.4 0.0 0.5 0.5 0.5 7.2 0.4 0.3 0.6 1.2 0.3 0.1 0.5 0.3 9.3 0.9 0.4 0.4 0.2 1.0 2.9 0.3 0.7 0.3 3.2 0.3 0.7 0.6 0.0 1.3 0.7 0.6 0.1 0.0 0.6 0.5 3.2 0.2 0.3 0.8 0.0 1.2 4.6 0.1 0.5 12.1 0.2 0.3 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.9 0.7 0.3 0.5 0.1 0.3 1.3 0.0 0.1 0.0 0.3 3.5 0.2 0.5 0.5 0.0 0.0 0.3 0.1 1.2 0.0 0.1 0.3 0.0 0.6 1.8 1.8 0.1 4.4 0.9 0.4 4.2 0.0 0.3 0.6 0.2 22.0 0.0 29.3 2.5 1.0 0.3 0.5 0.1 0.6 0.4 1.2 0.3 0.2 1.0 0.2 0.1 18.7 4.8 0.7 0.0 0.1 0.1 0.7 0.3 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.9 0.2 0.2 0.2 0.1 0.1 0.4 0.7 0.2 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.2 0.5 0.3 0.0 41.9 0.0 1.0 0.3 0.3 0.0 0.0 0.6 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.0 0.1 1.3 0.0 0.2 5.4 0.2 0.1 0.2 1.2 0.0 2.2 0.0 0.0 0.4 0.0 0.8 0.0 5.9 0.0 0.0 0.1 0.0 2.0 0.3 0.0 0.0 0.8 8.1 0.0 0.2 0.0 0.0 0.0 0.1 1.0 1.0 1.3 0.1 2.3 0.0 7.5 0.8 0.0 0.1 0.1 0.3 0.0 0.2 0.3 1.6 2.7 0.0 0.3 0.0 1.1 0.0 0.2 0.8 ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 89.3;Hofbauer cells: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 69.9" "Lineage enriched" "Detected in all" 5 "monocytes: 69.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 25.2 36.6 17.3 22.9 17.1 6.4 21.8 17.0 18.5 16.5 22.1 23.3 42.9 15.8 29.8 14.3 14.1 19.6 21.7 19.8 26.0 27.4 80.5 21.4 29.4 20.8 19.6 11.1 45.9 21.3 21.3 28.7 23.1 25.4 18.1 11.9 50.3 18.3 14.0 11.4 31.9 16.9 16.9 29.1 24.8 12.2 22.0 13.7 19.3 14.8 15.3 22.0 13.1 17.2 16.5 33.5 31.9 28.2 28.1 13.6 24.4 26.6 47.1 47.5 49.4 23.3 26.3 4.3 21.9 34.2 14.3 23.7 16.9 24.6 22.5 85.5 29.1 11.1 48.1 24.6 38.4 16.4 27.1 34.1 15.2 24.6 14.5 28.3 34.9 14.1 20.3 33.9 31.5 26.8 13.4 14.2 21.5 24.8 20.0 10.8 43.1 36.2 34.9 37.6 16.7 26.0 36.8 80.1 19.2 16.3 49.0 14.0 21.0 23.9 19.8 31.4 38.4 28.1 40.0 3.6 35.0 8.2 37.6 12.5 16.9 7.2 12.3 69.9 9.4 2.5 7.6 11.1 15.1 1.5 6.6 5.7 2.8 9.7 48.2 0.6 8.3 10.9 17.3 17.1 17.0 18.5 19.8 26.0 20.8 19.6 23.1 16.9 22.0 17.2 13.3 19.2 18.6 6.2 5.6 4.1 9.3 42.2 10.2 14.4 13.5 9.1 9.2 21.5 29.4 18.4 6.2 41.3 2.6 37.6 9.8 50.6 1.8 7.7 15.6 18.3 15.0 13.5 6.9 60.1 33.3 15.3 17.3 12.1 12.0 10.7 45.7 89.3 113.5 11.8 8.9 26.7 22.4 80.0 3.9 3.5 5.0 33.8 24.9 3.7 29.8 20.6 7.2 8.5 4.3 33.5 29.5 10.5 21.1 10.9 55.3 33.4 19.2 11.9 19.7 8.1 14.5 11.8 19.1 9.5 2.4 29.3 5.8 25.2 14.3 8.6 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 142.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.8;Proximal enterocytes: 78.2;Proximal tubular cells: 128.4;Syncytiotrophoblasts: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 97.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" 24.8 71.9 7.6 5.7 8.5 3.3 21.0 7.7 10.1 18.9 8.6 26.9 22.1 6.7 15.8 7.7 9.7 10.8 25.9 7.1 7.0 142.1 36.4 17.8 8.5 8.5 7.3 19.3 6.8 9.9 2.9 15.4 8.0 15.0 17.5 1.1 15.8 16.0 41.3 22.5 20.2 5.4 8.2 8.4 18.8 4.9 7.9 5.6 42.5 25.8 8.2 17.8 13.4 7.7 24.8 8.1 6.6 15.8 68.1 12.1 38.1 5.9 8.6 12.6 24.5 32.1 47.2 15.7 12.6 7.3 11.5 14.7 4.7 29.2 15.3 19.5 11.2 27.3 3.9 58.5 11.4 3.3 24.3 54.9 44.4 15.8 2.1 45.4 17.4 20.3 3.2 8.8 13.7 31.3 8.8 11.1 1.1 47.5 11.9 20.6 4.8 41.2 4.2 97.2 21.6 11.3 11.8 17.3 12.3 13.7 15.5 22.8 12.7 22.5 6.8 3.5 1.9 15.4 3.1 8.2 9.3 17.1 1.4 0.0 2.9 15.3 2.0 7.7 1.7 8.6 1.5 2.1 16.1 2.0 0.7 0.9 0.5 1.6 7.0 6.3 5.5 2.7 7.6 8.5 7.7 10.1 7.1 7.0 8.5 7.3 8.0 8.2 7.9 7.7 3.2 28.9 24.3 27.1 7.3 6.0 23.3 17.0 25.0 0.0 20.8 16.0 25.9 11.5 19.9 3.7 0.0 85.8 1.7 59.5 11.7 13.5 0.4 4.9 3.5 4.9 10.2 1.3 0.3 4.3 11.7 6.5 21.9 7.7 22.2 24.5 4.2 44.4 21.9 0.0 0.3 20.6 2.0 9.8 11.0 1.6 26.8 11.0 3.6 17.8 12.7 6.1 5.2 3.5 0.5 5.7 53.1 14.3 2.6 3.5 78.2 128.4 14.6 0.2 0.0 2.7 5.9 0.2 2.2 5.4 7.0 81.0 4.1 12.1 25.8 14.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623237-20698890 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "breast: 225.3" "Cell type enhanced" "Detected in many" "Early spermatids: 13.2;Late spermatids: 23.2;Theca cells: 8.4" "Group enriched" "Detected in many" 8 "liver cancer: 14.7;prostate cancer: 36.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "NTERA-2: 15.6" "Not detected" "Not detected" HPA046291 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 25: Spermatids - Spermatogenesis" "HPA046291: AB_10960704" "unprognostic (1.08e-2)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.49e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (9.46e-2)" "unprognostic (3.10e-1)" "unprognostic (8.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (8.24e-2)" "unprognostic (3.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 0.4 0.5 0.3 0.0 0.4 3.6 225.3 0.4 0.4 2.0 0.2 1.0 0.5 2.1 0.4 0.4 2.2 0.4 0.5 0.3 0.4 1.1 10.7 0.5 0.3 0.4 0.3 2.5 1.6 0.9 0.1 0.0 0.5 3.7 0.6 0.1 1.8 0.6 0.3 2.0 0.7 0.8 0.3 0.5 2.2 4.4 0.4 0.4 0.5 0.2 0.2 1.0 1.4 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.1 15.6 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.4 0.4 0.1 0.0 0.0 0.3 1.0 0.6 2.6 1.2 1.2 0.0 2.5 2.4 1.0 5.7 1.4 0.0 0.0 0.2 0.2 1.6 1.9 4.2 13.2 1.4 0.2 1.5 1.2 1.3 0.8 2.3 0.1 0.7 2.0 0.8 0.0 2.8 3.6 1.3 0.2 0.0 0.7 2.9 0.0 0.3 2.8 23.2 4.4 0.6 0.0 0.0 1.7 0.0 0.0 1.0 1.3 1.2 3.7 7.2 0.0 2.5 0.6 1.4 3.7 0.0 0.0 0.1 0.2 0.8 0.2 1.1 1.6 0.1 0.3 8.4 2.5 1.4 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 46.5;Astrocytes: 167.8;Early spermatids: 52.9;Hepatocytes: 53.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 7.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 70 "granulocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC diff: 14.3;ASC TERT1: 16.1;Hep G2: 42.6;hTERT-RPE1: 14.0;RH-30: 19.1;SK-BR-3: 18.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 22.7 14.5 5.2 1.5 5.1 0.1 7.3 5.2 5.3 8.3 9.3 2.2 0.7 9.1 12.1 1.5 8.0 8.1 6.8 4.7 4.9 25.9 40.0 6.4 1.5 5.5 6.4 16.7 2.0 13.7 4.4 4.0 5.2 5.7 1.0 4.8 12.1 5.5 3.5 1.7 1.5 6.3 4.9 2.1 1.4 2.3 6.5 1.1 8.8 5.7 1.1 2.8 5.0 5.5 0.0 0.2 3.4 0.0 14.3 16.1 0.1 2.2 11.0 1.7 1.9 0.4 0.1 0.0 0.0 5.0 5.2 0.1 0.0 0.0 1.0 0.0 2.2 0.0 0.0 42.6 4.8 0.1 0.0 10.8 0.0 0.5 0.0 14.0 0.4 0.0 0.0 0.0 7.8 1.0 0.1 0.2 4.8 0.0 0.0 0.0 19.1 2.7 0.1 0.1 3.1 0.0 0.0 18.0 0.1 7.1 7.9 0.5 0.0 2.8 2.7 0.2 1.2 0.1 0.1 0.1 3.5 0.0 3.4 7.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 5.2 5.1 5.2 5.3 4.7 4.9 5.5 6.4 5.2 4.9 6.5 5.5 1.3 22.4 46.5 167.8 0.2 0.9 9.5 0.0 2.2 37.8 5.6 3.0 21.8 14.3 3.2 12.9 4.2 1.5 0.1 0.1 5.9 6.4 52.9 3.9 14.8 1.5 0.0 0.0 1.5 2.9 0.8 12.1 0.0 2.7 0.0 8.8 1.8 53.6 0.7 28.6 1.6 0.1 0.0 3.2 0.6 9.4 23.9 0.8 0.0 35.6 0.1 16.4 0.0 16.6 0.7 0.1 0.1 23.7 0.0 3.0 1.1 31.7 3.7 5.3 6.6 18.6 9.9 4.6 0.6 0.4 0.1 0.5 0.6 13.2 1.2 3.7 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTB ENSG00000075624 "Actin beta" P60709 7 5526409-5563902 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 22882.9;Pancreatic endocrine cells: 14370.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002621, HPA041264, HPA041271" Supported NA NA 5800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "CAB002621: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (1.66e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (9.80e-3)" "unprognostic (1.57e-3)" "unprognostic (1.73e-1)" "unprognostic (5.99e-2)" "unprognostic (3.33e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" 2558.1 1235.8 2143.2 4250.8 2321.0 3598.4 2009.8 2400.1 2776.1 2274.6 2183.3 6581.2 1659.0 5033.9 1630.3 2928.9 2943.6 1772.1 817.6 2355.6 2315.8 1313.6 1759.9 2876.0 4394.2 2654.8 2338.9 1711.5 761.9 838.5 731.4 1817.2 2569.2 2027.1 2338.4 488.2 1470.2 2943.2 465.1 1541.7 2825.9 5736.8 2457.9 3009.5 2869.7 558.3 2483.4 3278.4 1317.9 524.0 4602.3 3720.8 2223.5 3045.4 7791.1 5198.8 5604.1 4658.2 2321.1 3120.3 6654.3 6049.6 4853.2 6209.7 4619.4 8249.5 4361.9 4522.7 4557.0 9445.4 4904.8 4820.3 3279.5 9453.9 4507.4 5324.6 1668.7 3974.3 4579.6 4520.6 3538.8 4733.2 9853.8 4098.5 2786.7 6863.0 1738.0 4128.6 5073.2 3561.3 2189.7 3513.0 6603.4 7531.9 4055.1 13162.1 6813.7 2468.5 3490.8 5658.6 3351.4 3419.7 5904.6 3175.8 1633.1 2746.9 5754.7 5822.1 2400.3 5088.3 5859.7 5314.8 7975.3 10437.4 7019.9 7000.1 8802.8 1902.3 2442.5 5082.1 5772.0 6622.6 12412.7 14674.1 18104.2 29636.6 10647.1 19648.6 8327.7 5139.6 7639.4 9512.9 19292.5 4844.1 5592.0 7894.3 18040.6 6233.1 22870.8 7122.2 11463.2 37406.8 2143.2 2321.0 2400.1 2776.1 2355.6 2315.8 2654.8 2338.9 2569.2 2457.9 2483.4 3045.4 2775.4 1150.6 680.4 142.4 4118.9 5737.0 9776.6 5792.0 3110.2 146.7 1564.0 2047.2 145.3 1080.9 2763.3 2144.5 85.5 3647.7 3989.3 3419.3 2277.4 6508.8 101.3 1422.1 2344.0 2768.4 1451.5 3170.9 129.3 6365.4 12480.2 2958.5 3136.1 2041.6 1539.9 2372.0 2163.5 2590.6 13977.7 269.2 101.3 2006.7 3694.5 7392.0 11420.0 199.7 1766.7 8486.4 2995.4 259.5 22882.9 1654.4 5237.9 116.1 302.2 14370.0 2899.8 2680.3 3040.4 4764.9 4968.2 2149.2 1453.8 146.7 3287.0 1398.2 5423.9 133.8 381.9 4376.1 4722.2 3257.7 5961.7 1688.9 1966.6 6941.4 ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "heart muscle: 11410.0" "Cell type enriched" "Detected in some" 30 "Cardiomyocytes: 9746.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1131.8;LHCN-M2: 4544.5;RH-30: 2053.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA 2400000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037330: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (8.18e-3)" "unprognostic (3.74e-2)" "unprognostic (4.82e-3)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (2.26e-1)" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (5.68e-4)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (9.32e-4)" 51.1 1.8 1.9 24.7 1.7 0.0 11.9 2.1 2.6 8.6 1.3 4.0 0.8 6.9 1.1 22.8 1.6 11.8 11410.0 1.9 2.8 1.5 0.6 3.9 2.6 2.7 2.8 3.2 12.9 1.0 2.2 8.9 3.0 73.0 3.6 31.6 11.5 538.1 135.2 4.6 0.6 8.8 1.4 1.3 9.3 0.5 4.0 11.3 2.4 195.0 0.2 439.6 16.1 1.5 0.0 0.2 0.1 0.0 0.2 3.3 0.2 2.2 0.7 5.2 1.3 0.0 0.0 0.0 1.3 1131.8 0.2 0.0 0.4 0.0 1.3 0.0 0.0 0.1 23.9 0.0 0.1 1.4 0.0 457.2 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 4544.5 0.0 0.0 0.0 3.8 0.0 0.0 0.0 2053.3 0.0 0.0 0.0 0.1 0.1 4.0 0.0 0.0 31.2 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 2.1 2.6 1.9 2.8 2.7 2.8 3.0 1.4 4.0 1.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 11.9 0.1 0.0 9746.1 0.0 0.0 0.0 20.9 0.1 0.0 0.0 1.9 0.0 5.0 0.0 0.1 69.2 0.0 0.0 0.2 0.2 4.3 315.2 0.0 0.0 0.0 0.1 0.4 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 63.4 86.5 1.0 0.7 0.0 0.4 0.3 0.1 0.1 0.0 0.0 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037193, HPA047443" Approved Approved Microtubules NA NA 560000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Microtubules "CAB037193: AB_258253, HPA047443: AB_2680049" "unprognostic (9.64e-3)" "unprognostic (1.92e-2)" "unprognostic (8.34e-2)" "unprognostic (4.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.77e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (4.13e-1)" 59.4 58.8 98.3 39.4 100.6 36.8 51.5 101.9 108.4 50.9 78.4 90.0 37.8 61.8 37.5 61.6 47.4 36.1 93.0 101.9 108.0 49.0 40.4 58.5 33.7 116.3 105.9 36.9 41.9 56.5 54.7 45.3 116.9 53.0 41.7 41.9 46.4 51.9 174.3 65.1 49.1 69.0 97.4 48.7 56.2 40.4 104.0 56.8 41.2 127.0 42.2 74.8 51.2 104.4 80.5 95.8 113.5 117.1 138.0 109.2 45.5 100.3 177.3 154.4 142.4 52.7 63.3 54.4 75.2 149.5 76.2 78.3 109.9 123.7 106.5 70.7 75.8 72.9 53.4 77.9 99.6 56.9 65.0 112.4 89.6 141.2 100.7 155.7 201.6 88.7 60.5 53.5 154.6 67.1 103.5 97.9 45.4 62.5 86.2 78.5 146.0 35.0 125.2 43.9 40.5 88.8 60.1 35.4 75.1 98.3 130.0 38.9 147.0 74.7 71.5 83.6 102.1 54.0 58.8 63.3 78.7 98.3 45.9 32.2 40.7 44.3 31.1 51.8 25.5 18.8 22.0 30.4 40.6 17.6 18.0 20.7 31.2 23.9 57.0 20.8 33.6 39.2 98.3 100.6 101.9 108.4 101.9 108.0 116.3 105.9 116.9 97.4 104.0 104.4 40.0 57.7 41.0 10.1 23.4 33.8 24.0 42.3 13.1 26.6 22.1 17.1 51.6 14.3 34.8 27.6 16.7 54.9 23.8 52.4 54.8 75.5 53.0 15.3 21.0 45.2 39.6 45.9 14.9 77.5 63.3 36.9 23.4 19.3 32.3 27.3 34.6 24.1 73.9 26.9 15.5 24.4 46.8 37.6 38.2 53.9 33.2 44.5 51.6 5.6 70.3 31.5 38.1 10.1 15.3 92.0 36.8 36.1 30.0 26.7 40.9 45.6 26.5 24.5 46.0 17.1 48.5 61.9 14.0 27.3 32.4 104.7 28.2 32.9 24.2 26.6 ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 56.7;Cone photoreceptor cells: 62.6;Extravillous trophoblasts: 81.8;Langerhans cells: 49.3;monocytes: 83.5;Plasma cells: 53.8;Rod photoreceptor cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.3;eosinophil: 139.9;memory B-cell: 50.8;naive B-cell: 53.5;neutrophil: 70.5;plasmacytoid DC: 66.8" "Group enriched" "Detected in many" 5 "B-cells: 53.5;dendritic cells: 66.8;granulocytes: 139.9" "Cell line enhanced" "Detected in many" "HDLM-2: 109.7;U-251 MG: 206.5" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Vesicles "HPA055537: AB_2797253" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.64e-2)" "unprognostic (1.81e-3)" "unprognostic (2.63e-1)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.90e-12)" "unprognostic (1.44e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" 4.9 3.6 2.6 24.0 3.3 7.7 2.7 5.3 4.6 4.9 0.4 22.8 5.8 8.0 2.6 5.1 7.4 8.9 24.7 3.1 3.8 2.1 9.6 13.2 29.0 5.1 4.5 3.5 0.9 0.1 1.8 13.1 4.7 7.6 6.7 22.6 1.9 6.3 6.5 1.4 18.7 16.3 3.1 22.6 9.6 1.6 4.5 7.4 4.2 2.8 30.2 18.8 5.2 3.9 38.8 6.0 11.5 0.1 0.8 0.7 73.7 45.0 16.0 27.5 20.5 19.9 30.7 19.9 2.4 23.4 5.7 32.4 1.8 2.9 24.9 109.7 1.1 0.1 3.3 2.7 6.5 0.1 0.0 5.2 0.1 21.5 4.3 32.7 31.5 0.0 5.7 2.8 59.4 0.0 0.0 0.1 12.3 0.0 19.3 0.6 65.9 16.8 2.9 0.6 5.2 3.5 0.0 15.9 2.3 45.3 0.2 0.6 48.7 29.6 31.7 6.8 206.5 11.8 0.4 69.6 6.7 0.1 13.5 128.3 13.1 139.9 1.5 1.2 3.5 50.8 14.4 3.3 4.2 53.5 0.4 0.4 70.5 0.4 0.1 66.8 16.6 9.2 2.6 3.3 5.3 4.6 3.1 3.8 5.1 4.5 4.7 3.1 4.5 3.9 1.5 6.4 0.6 2.0 56.7 2.2 0.1 1.2 0.0 37.7 0.5 0.4 5.6 0.0 0.7 3.7 62.6 1.1 22.0 0.1 0.0 0.5 4.1 0.5 6.8 5.6 0.0 1.7 24.2 1.5 81.8 6.5 0.5 0.2 0.0 0.3 4.2 7.5 1.7 15.2 21.2 0.1 0.0 9.0 49.3 1.3 5.6 12.4 1.8 10.3 83.5 2.4 1.0 13.0 28.7 2.2 0.1 7.9 53.8 0.2 0.0 0.1 0.1 43.9 6.6 12.3 13.3 0.0 1.1 2.5 1.4 8.3 24.0 1.7 0.3 0.2 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;Rod photoreceptor cells: 624.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" 104.4 70.0 96.4 60.7 119.7 65.9 89.1 86.7 117.7 96.5 46.4 127.9 65.5 121.4 57.9 71.9 96.3 69.0 111.2 99.2 90.9 74.1 53.7 93.5 65.3 91.5 100.4 129.5 56.4 67.5 70.1 66.0 92.3 86.1 62.7 269.1 61.9 107.3 166.3 69.4 92.3 110.2 76.0 88.9 84.3 53.2 113.2 76.0 71.7 115.0 62.1 115.3 82.9 116.2 74.7 61.2 142.0 73.8 205.8 152.6 53.2 123.2 146.9 125.6 105.3 90.5 91.8 38.7 63.0 212.3 146.6 46.6 107.5 103.4 104.3 49.9 49.4 109.5 50.4 87.9 100.4 65.8 74.7 151.6 95.2 110.4 44.0 130.1 158.5 71.9 116.0 90.8 145.1 43.7 203.7 91.6 80.0 67.9 85.7 89.1 78.6 45.7 91.2 162.2 84.8 110.0 88.9 35.8 76.9 107.0 84.2 61.7 193.4 102.1 52.4 84.7 103.0 72.5 63.3 48.9 98.2 80.4 100.9 20.1 7.6 35.5 19.1 7.3 17.6 23.8 10.6 16.3 12.0 31.2 9.8 11.8 10.5 27.2 11.4 25.4 14.8 16.0 96.4 119.7 86.7 117.7 99.2 90.9 91.5 100.4 92.3 76.0 113.2 116.2 89.3 70.5 45.4 141.3 66.5 26.9 29.8 33.0 27.9 99.5 41.2 41.5 78.0 40.0 46.3 60.7 402.4 35.5 84.0 51.3 15.6 37.3 48.5 43.9 61.2 89.4 57.7 57.9 85.7 45.8 32.5 72.9 39.8 58.1 37.3 53.0 84.3 41.8 41.8 111.0 83.2 39.3 28.5 51.6 42.2 35.9 77.6 47.4 35.6 72.1 58.3 233.8 120.5 68.9 178.6 53.2 39.4 121.9 49.7 35.8 48.6 44.6 40.4 624.3 98.6 58.4 73.1 45.3 33.2 30.5 36.7 36.5 55.6 80.7 45.1 33.0 ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1795.3;Excitatory neurons: 3843.1;Inhibitory neurons: 2738.1;Oligodendrocyte precursor cells: 2036.3;Oligodendrocytes: 1210.5" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.8;SH-SY5Y: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" 0.8 3.9 21.1 0.8 25.5 0.0 0.6 49.6 29.7 1.3 0.0 4.3 0.4 2.2 0.9 0.7 0.9 0.9 1.9 31.1 12.1 1.0 0.5 1.7 0.0 0.0 0.6 1.6 0.3 0.1 23.7 0.1 1.1 1.0 1.3 7.1 1.2 1.4 0.3 0.4 1.4 3.3 0.0 0.6 1.3 1.9 18.2 0.1 0.8 1.4 0.0 2.6 1.4 19.1 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.0 1.2 1.0 0.0 0.0 8.8 19.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 21.1 25.5 49.6 29.7 31.1 12.1 0.0 0.6 1.1 0.0 18.2 19.1 3.1 0.0 0.0 1795.3 0.3 0.0 0.1 0.0 0.0 47.3 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.2 4.8 0.6 0.0 0.0 3843.1 0.0 0.0 2.1 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 2738.1 0.0 0.0 0.6 0.0 3.1 5.0 1.3 0.0 216.4 1.0 0.8 0.0 2036.3 1210.5 0.1 0.0 8.6 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.6 7.4 11.8 3.2 0.2 0.0 0.0 0.0 0.5 0.0 0.1 ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.5;kidney: 20.3;urinary bladder: 42.6" "Group enriched" "Detected in some" 4 "Collecting duct cells: 108.5;Pancreatic endocrine cells: 98.9;Urothelial cells: 363.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 31.2;CAPAN-2: 113.3;HaCaT: 25.3;PC-3: 36.6;RPTEC TERT1: 50.9;RT4: 132.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 3.4 0.0 0.3 0.0 0.2 0.1 17.5 0.8 6.1 0.0 0.0 0.0 20.3 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.0 0.1 0.0 3.2 1.7 0.0 0.0 3.2 0.0 0.0 0.0 1.4 0.6 0.0 0.1 6.2 0.0 5.9 42.6 6.4 0.0 31.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.3 0.0 2.0 0.0 0.0 25.3 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.5 36.6 0.0 0.0 0.0 50.9 132.6 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.8 0.0 0.1 0.0 25.4 0.0 0.6 0.0 5.5 1.9 0.7 12.8 13.6 108.5 0.0 0.0 0.0 1.5 23.5 30.8 0.0 7.0 5.0 0.7 0.0 0.0 0.1 18.9 0.1 0.8 3.6 46.9 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 0.0 0.0 39.1 1.2 0.7 14.6 0.0 0.0 0.2 1.1 0.0 0.2 2.6 0.0 0.1 1.0 0.1 0.2 363.7 ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 38.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Pancreatic endocrine cells: 20.5;Prostatic glandular cells: 6.0;Squamous epithelial cells: 14.4;Syncytiotrophoblasts: 7.3;Urothelial cells: 20.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;HBEC3-KT: 21.0;hTCEpi: 31.8;OE19: 18.4;U-87 MG: 26.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" 0.2 0.7 0.0 0.2 0.0 0.0 2.2 0.4 0.1 4.7 0.0 1.2 0.0 0.3 0.0 18.3 1.1 0.7 0.6 0.0 1.9 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 2.0 0.0 0.2 1.5 0.0 2.4 0.0 0.6 38.8 0.2 0.1 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.9 4.1 4.3 9.6 0.0 8.9 1.2 0.0 0.0 0.0 0.0 1.0 0.0 5.1 0.1 0.0 2.4 0.0 0.0 0.0 0.0 8.2 13.2 0.0 21.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 31.8 0.4 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 1.2 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.4 1.8 0.1 0.2 0.0 0.0 0.0 0.8 0.1 1.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 4.4 0.0 3.5 0.7 1.6 0.3 0.2 0.0 0.0 0.6 3.4 15.1 0.4 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.5 0.0 0.0 6.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 14.4 0.0 7.3 0.0 0.0 0.1 20.5 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.9;lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "dendritic cells: 32.0;Microglial cells: 11.2;NK-cells: 43.3;Plasma cells: 16.4;T-cells: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 125.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 39.4;OE19: 13.2;RPMI-8226: 6.2;THP-1: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" 0.3 0.3 0.3 5.0 0.2 1.4 0.7 0.2 0.2 0.2 0.1 1.7 3.7 0.3 0.1 0.6 0.5 0.1 0.0 0.3 0.4 0.0 0.2 0.9 10.5 0.8 0.4 0.0 0.0 0.1 0.2 0.0 0.6 0.3 1.3 0.0 1.3 0.3 0.1 0.1 3.9 0.3 0.6 5.8 0.4 0.4 0.4 1.6 0.3 0.0 10.5 1.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.4 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 3.6 3.6 13.2 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.1 125.9 33.3 0.1 16.9 12.0 4.8 19.1 2.4 8.6 1.2 11.2 0.5 29.9 0.1 68.8 0.2 9.0 0.3 0.2 0.2 0.2 0.3 0.4 0.8 0.4 0.6 0.6 0.4 0.3 0.3 0.0 1.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.2 32.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.6 0.0 0.3 0.0 3.2 0.0 11.2 1.7 0.0 43.3 0.0 0.3 0.0 0.0 0.0 16.4 0.1 2.9 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 7.1 0.0 0.7 0.0 ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Excitatory neurons: 902.7;Inhibitory neurons: 646.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 252.8;hTEC/SVTERT24-B: 130.3;NTERA-2: 100.0;SH-SY5Y: 168.3;U-2197: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" 19.8 19.9 11.0 8.2 13.4 0.0 17.8 6.5 26.3 16.4 5.0 15.3 5.8 12.4 15.0 23.6 23.1 23.1 28.5 13.9 14.6 21.4 38.5 64.9 8.9 8.6 10.7 36.3 9.7 27.5 20.5 48.8 7.6 30.0 10.9 25.2 36.7 19.4 4.4 12.9 13.4 12.7 7.0 19.9 15.5 4.2 15.5 10.4 43.2 19.7 8.7 13.2 23.4 15.0 18.2 9.9 252.8 0.0 30.3 35.3 3.4 6.4 14.8 2.5 2.9 0.0 0.0 0.1 69.6 34.6 7.1 10.1 20.3 28.0 2.3 0.5 41.5 0.0 7.0 16.6 11.8 0.0 0.4 32.5 1.8 130.3 12.9 17.8 42.9 0.0 0.0 0.0 3.4 0.2 0.0 0.1 100.0 0.0 7.1 0.0 34.9 0.0 56.9 3.8 11.7 168.3 0.0 6.3 0.0 73.5 0.4 74.7 27.5 26.0 28.9 118.9 9.3 0.0 0.0 0.2 14.9 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 13.4 6.5 26.3 13.9 14.6 8.6 10.7 7.6 7.0 15.5 15.0 25.3 3.2 2.2 23.8 0.2 0.0 7.0 0.0 2.2 48.5 6.6 11.2 44.1 10.0 3.1 5.5 6.2 0.4 0.1 2.1 0.0 4.7 1.4 11.7 10.3 36.9 0.0 0.0 902.7 1.6 0.4 19.6 0.5 25.4 0.0 32.3 30.0 39.3 0.9 33.7 646.8 2.0 0.0 3.1 0.0 1.4 23.3 1.1 0.0 69.3 0.0 19.0 0.0 11.1 13.0 0.8 3.6 17.7 0.0 10.4 0.0 7.8 0.0 3.9 19.7 2.5 19.8 1.5 3.5 4.1 0.0 0.4 0.5 43.1 3.5 3.0 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 8 "Astrocytes: 2207.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.5;HAP1: 23.0;K-562: 9.8;NTERA-2: 11.6;SCLC-21H: 11.1;SuSa: 15.0;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.0 533.0 36.9 0.0 47.8 0.6 3.6 12.7 40.3 0.9 22.4 1.0 0.3 0.1 0.7 2.4 0.2 12.3 0.2 39.1 11.6 21.5 42.3 2.1 0.0 9.4 12.8 0.2 1.5 0.8 15.1 4.1 9.4 1.3 1.0 18.2 2.3 0.2 0.2 2.1 0.5 0.0 7.3 0.3 1.1 1.4 18.3 0.8 17.5 0.0 0.4 10.4 1.9 26.1 0.5 2.1 15.5 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 1.7 0.2 0.3 0.4 0.0 0.4 0.2 23.0 0.2 0.0 1.0 4.3 4.1 2.0 1.4 0.0 0.3 0.1 0.0 4.8 0.0 0.1 0.1 0.0 0.1 9.8 2.6 0.0 2.1 0.1 0.2 11.6 2.9 4.2 0.0 0.4 2.1 0.0 0.5 11.1 2.7 3.4 2.2 0.2 15.0 5.9 0.0 0.8 0.4 1.9 0.5 1.1 13.4 4.1 0.6 0.7 0.2 0.0 3.2 0.9 2.8 1.0 0.7 1.7 1.5 1.1 1.4 0.5 2.9 1.7 0.9 4.6 1.1 0.5 1.2 1.6 0.2 36.9 47.8 12.7 40.3 39.1 11.6 9.4 12.8 9.4 7.3 18.3 26.1 0.4 25.6 26.5 2207.3 0.0 0.0 6.1 0.0 1.8 28.0 15.5 7.4 2.4 2.8 5.6 5.5 264.8 3.0 0.4 0.6 1.9 1.9 43.5 3.3 0.3 1.1 7.3 0.0 54.0 4.2 2.6 1.1 4.6 1.9 0.0 6.7 0.0 12.4 0.2 10.1 21.9 0.4 0.0 0.8 0.0 54.8 0.6 0.5 0.0 51.5 1.2 8.9 1.0 40.2 7.4 1.7 1.2 0.4 0.1 2.1 0.1 24.2 7.3 84.4 0.0 0.3 0.4 3.6 4.5 2.9 0.0 4.1 0.6 0.2 1.2 9.0 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 141.5 71.3 48.3 52.5 48.2 28.5 111.9 48.0 56.0 92.7 55.8 158.8 94.2 134.8 142.2 114.4 95.9 69.3 124.3 45.9 54.6 175.4 264.1 73.5 51.3 47.6 48.5 118.4 49.4 50.1 41.4 60.9 47.9 116.2 100.8 36.0 65.4 124.6 80.9 54.8 94.3 118.0 49.7 51.6 91.3 52.2 48.6 83.3 79.2 75.8 55.5 158.9 73.9 51.4 84.0 66.9 194.8 110.0 344.7 316.0 116.6 136.6 237.6 143.8 125.2 77.1 96.7 96.5 77.5 197.8 92.8 69.8 135.0 188.7 137.7 69.9 56.6 67.1 83.3 306.7 332.2 118.4 51.9 287.3 143.1 108.3 84.7 151.0 112.8 99.8 125.8 53.3 192.3 94.9 160.4 105.4 156.7 20.6 79.8 115.4 108.9 50.9 230.2 96.0 74.0 97.0 82.7 96.6 155.9 141.8 78.2 82.2 85.4 130.5 82.9 86.4 95.2 55.9 74.4 135.4 134.2 77.4 135.7 21.8 21.2 35.8 32.6 18.9 29.5 26.0 35.3 30.4 23.8 26.2 34.0 31.9 3.0 51.3 14.1 20.5 49.5 32.8 48.3 48.2 48.0 56.0 45.9 54.6 47.6 48.5 47.9 49.7 48.6 51.4 69.0 105.8 78.2 22.9 48.1 39.6 85.9 257.5 109.3 31.8 32.1 74.3 127.4 78.6 94.3 55.2 10.4 290.1 51.8 80.4 197.6 94.8 24.0 146.9 159.1 56.3 79.7 45.8 14.3 83.8 277.2 131.2 37.8 113.0 26.6 83.3 47.2 188.0 118.1 38.7 12.0 101.8 87.5 48.6 27.1 22.0 187.4 43.4 53.4 15.9 63.2 152.4 77.2 27.6 13.9 78.4 86.0 255.1 41.5 34.9 95.2 316.0 56.8 46.5 111.7 55.6 127.7 30.5 48.5 74.9 23.0 83.0 58.5 147.0 104.8 68.1 ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 10.0;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.1;Pancreatic endocrine cells: 9.4;Proximal enterocytes: 7.4;Proximal tubular cells: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 37.1;hTCEpi: 23.8;Karpas-707: 38.2;SK-MEL-30: 25.9;U-266/70: 25.6" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" 0.3 0.2 0.2 1.7 0.3 0.4 0.4 0.6 0.4 0.9 0.0 1.1 3.7 0.1 1.7 3.0 0.2 1.2 0.1 0.1 0.1 8.3 3.8 0.8 2.6 0.2 0.2 0.0 15.5 0.3 0.4 0.2 0.2 2.6 0.6 0.0 5.6 0.4 0.0 0.4 2.9 0.2 0.0 1.1 4.0 0.6 0.4 1.0 11.6 0.0 1.9 0.3 0.3 0.2 1.8 0.3 0.5 2.0 1.2 2.1 7.0 9.1 0.8 1.3 2.9 3.9 1.5 0.0 1.3 7.9 1.5 1.4 2.0 1.2 0.5 17.3 0.0 0.1 0.5 2.8 37.1 3.8 2.5 7.5 23.8 4.1 8.6 0.1 0.1 10.1 2.4 38.2 0.3 5.8 0.3 0.7 1.2 10.7 5.7 0.0 0.0 15.1 1.7 0.2 1.0 4.0 0.1 5.5 25.9 1.2 7.6 12.2 0.0 0.0 8.1 0.0 0.0 25.6 4.2 5.0 0.3 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.1 0.1 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.0 3.0 0.0 2.5 0.0 0.9 1.0 0.0 0.0 3.6 1.8 1.4 1.5 0.5 0.0 0.0 0.1 0.6 3.9 3.9 2.6 0.0 0.5 0.4 0.3 1.2 0.0 0.0 10.0 0.7 0.2 7.1 1.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 7.1 0.0 0.0 0.3 0.2 0.0 0.4 1.8 0.0 0.6 0.0 1.0 0.0 0.0 9.4 1.4 0.0 3.1 2.0 7.4 28.1 0.1 0.0 0.0 1.1 0.7 0.2 1.0 0.0 0.4 1.0 1.2 0.0 1.1 0.9 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Basal respiratory cells: 75.6;Langerhans cells: 31.9;Suprabasal keratinocytes: 64.4;Urothelial cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Cell line enhanced" "Detected in many" "GAMG: 160.8;HMC-1: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 0.5 1.1 7.5 1.7 9.4 0.8 0.7 7.0 11.7 2.4 9.0 8.6 0.2 0.7 0.5 9.1 0.9 1.1 1.6 9.1 7.3 0.3 0.1 1.9 0.3 7.7 7.7 0.0 1.3 0.0 1.4 5.0 7.1 1.3 6.6 2.8 1.4 0.1 0.1 8.5 1.3 1.3 6.4 0.2 1.2 0.3 8.3 0.4 0.1 0.5 1.3 14.2 5.2 8.2 34.1 18.3 0.6 0.7 5.8 11.1 0.7 6.4 28.4 18.3 22.6 8.8 34.6 4.4 7.8 5.7 160.8 51.9 7.9 47.8 24.2 9.7 18.0 32.7 5.8 13.0 22.3 0.0 162.6 6.5 20.1 26.0 60.4 31.3 9.3 5.1 1.6 0.1 18.2 8.9 2.2 6.6 1.9 72.0 25.5 0.1 0.4 0.0 19.1 9.1 0.8 1.2 14.3 3.4 9.0 13.4 0.1 5.1 7.7 6.5 17.1 18.3 30.3 2.8 0.0 0.0 25.8 0.0 9.2 14.9 4.2 2.8 0.0 5.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.4 0.0 2.6 0.1 0.0 1.7 7.5 9.4 7.0 11.7 9.1 7.3 7.7 7.7 7.1 6.4 8.3 8.2 0.1 3.2 4.2 18.9 0.2 73.5 21.0 75.6 27.3 0.2 1.3 1.9 0.9 1.5 20.2 0.0 0.0 10.9 0.1 10.8 0.0 6.6 0.9 0.9 0.6 1.7 2.4 3.4 0.9 0.9 3.2 4.9 2.0 1.2 0.0 0.1 2.2 0.0 4.5 0.0 1.1 1.7 2.0 1.4 31.9 0.4 0.0 6.7 7.2 3.7 1.3 7.9 0.0 1.0 1.0 1.0 7.2 0.0 0.0 15.6 0.2 0.0 8.3 0.5 0.0 0.7 2.1 0.5 1.4 23.0 64.4 6.2 0.3 0.3 5.7 32.4 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.6;cervix: 7.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.2;Excitatory neurons: 2.1;Inhibitory neurons: 2.4;Oligodendrocyte precursor cells: 1.0;Smooth muscle cells: 2.4" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.7;BJ: 7.5;CAPAN-2: 3.3;fHDF/TERT166: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" 1.2 0.4 5.0 0.0 0.6 0.0 0.8 0.3 4.8 7.2 0.0 2.0 0.0 3.5 0.3 0.2 2.0 0.2 0.3 7.5 4.2 0.3 0.1 2.3 0.0 2.7 4.9 0.6 0.3 0.2 0.0 0.1 2.4 3.4 0.1 0.0 0.2 1.7 0.5 0.4 0.2 0.3 1.3 1.4 1.6 0.7 9.6 0.0 0.8 0.4 0.0 2.4 2.9 1.1 0.0 1.7 0.1 0.0 0.0 0.0 0.0 7.5 1.3 0.4 0.1 0.3 3.3 0.0 0.0 4.4 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.3 4.8 7.5 4.2 2.7 4.9 2.4 1.3 9.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.7;lung: 13.1;placenta: 29.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.7;Cytotrophoblasts: 84.5;Sertoli cells: 52.6;Syncytiotrophoblasts: 38.4" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;PC-3: 2.6;THP-1: 4.5;TIME: 5.8;U-937: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA067972: AB_2685936" "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" 4.0 0.2 5.5 0.3 10.3 0.5 2.3 0.7 12.0 0.1 0.2 3.1 0.9 0.1 0.1 0.9 0.1 0.1 23.7 6.8 3.3 1.1 1.4 13.1 0.2 1.8 3.1 0.0 1.3 0.8 0.8 29.1 2.4 4.4 0.6 2.1 5.4 0.1 2.3 0.4 1.9 0.1 0.9 1.5 0.7 0.5 5.0 0.1 0.6 0.0 0.3 0.7 0.1 7.8 1.4 0.8 0.1 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.3 1.0 0.2 0.2 0.0 0.4 0.3 0.1 0.1 0.1 7.1 0.4 0.3 0.1 0.1 0.0 0.2 0.4 0.0 0.7 0.0 1.3 0.1 0.1 1.0 0.0 0.1 0.1 0.8 1.1 0.9 0.3 0.2 2.6 0.2 0.2 0.1 0.0 1.1 0.1 0.2 0.0 0.5 0.0 0.3 0.2 4.5 5.8 0.2 0.1 0.1 0.1 0.0 0.0 0.3 0.0 3.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 10.3 0.7 12.0 6.8 3.3 1.8 3.1 2.4 0.9 5.0 7.8 1.1 19.2 7.8 15.0 0.5 1.0 3.9 0.8 1.2 21.8 1.0 0.5 85.7 2.8 9.8 0.0 0.0 84.5 3.0 0.1 1.9 0.1 0.1 0.4 0.6 11.3 0.0 0.0 12.8 0.2 5.2 5.3 0.0 0.3 0.0 0.0 0.4 0.2 4.4 13.5 2.5 3.3 2.0 2.2 1.6 0.2 0.0 2.8 1.8 7.5 0.6 0.7 3.1 1.0 0.3 0.1 1.4 0.4 1.2 6.1 0.8 0.0 12.1 1.7 52.6 0.4 8.2 0.5 0.2 0.1 0.0 38.4 4.8 0.0 0.6 3.9 ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.8;Hofbauer cells: 1.1;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Fibroblasts - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" 0.3 0.0 1.2 0.4 1.1 0.2 0.3 0.5 0.9 0.4 1.5 2.1 0.2 0.7 1.1 0.1 4.1 1.7 0.0 0.9 0.7 0.0 0.0 0.1 0.1 8.1 2.7 11.7 0.0 0.0 0.0 2.9 3.1 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 4.6 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.5 0.9 0.9 0.7 8.1 2.7 3.1 0.4 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.4;Cardiomyocytes: 39.3;Early spermatids: 105.4;Endothelial cells: 72.0;Extravillous trophoblasts: 47.1;Hepatic stellate cells: 47.2;Late spermatids: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.6;HUVEC TERT2: 20.8;TIME: 33.9;WM-115: 79.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" 23.9 2.8 1.7 2.1 0.9 0.1 15.2 1.1 1.3 4.2 1.0 3.5 0.8 7.1 0.6 4.3 10.1 4.0 26.1 0.9 1.0 4.1 2.1 13.3 2.3 1.4 1.1 3.3 1.0 6.1 2.4 14.4 1.4 3.3 0.7 1.3 3.4 1.9 31.6 6.0 3.4 3.5 1.1 2.9 2.4 2.3 1.8 3.4 7.4 16.6 0.8 4.6 3.7 0.9 7.0 2.4 0.1 0.3 9.9 2.1 42.6 1.5 5.5 5.4 8.9 0.1 4.1 0.0 3.3 2.5 13.7 1.4 0.8 6.2 2.2 0.0 1.0 1.6 0.9 0.0 5.2 0.0 0.1 7.3 1.0 3.0 11.6 4.3 20.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 1.0 0.0 5.4 0.0 0.0 0.0 3.5 1.1 0.7 1.1 4.4 0.1 14.8 1.5 0.2 0.4 33.9 2.5 7.7 0.1 1.2 0.0 0.0 0.0 0.5 0.1 79.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.9 1.1 1.3 0.9 1.0 1.4 1.1 1.4 1.1 1.8 0.9 62.4 0.0 1.3 0.3 0.2 1.5 1.4 4.6 0.0 0.3 0.4 0.5 39.3 1.5 4.1 0.0 0.0 14.2 0.2 0.0 0.0 0.3 105.4 0.3 0.4 72.0 0.0 0.0 2.9 0.0 47.1 4.5 0.0 0.2 1.3 0.0 47.2 0.6 2.7 0.0 1.2 0.0 0.0 4.2 1.3 50.4 9.6 0.7 7.2 10.3 0.0 0.5 0.0 2.0 0.3 0.0 0.0 15.8 0.0 4.0 0.0 0.8 6.4 5.3 13.1 4.6 4.0 0.5 4.8 0.3 1.4 6.4 0.5 1.8 0.0 5.4 AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 154.9;Excitatory neurons: 491.3;Inhibitory neurons: 300.7;Oligodendrocyte precursor cells: 211.6" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "Daudi: 51.1;U-698: 56.5" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" 3.3 1.6 3.1 6.2 3.9 11.2 11.6 17.4 13.2 3.5 0.0 5.1 1.1 7.7 0.8 3.5 4.5 2.2 4.3 9.7 5.0 1.4 1.7 6.5 14.2 2.2 0.0 6.3 0.4 0.1 4.4 6.2 1.8 16.2 2.2 4.2 1.9 2.5 0.7 0.9 6.0 5.9 0.0 7.3 4.6 5.4 0.0 7.7 1.2 0.7 12.2 6.7 2.2 9.8 0.2 0.0 18.0 6.4 0.0 0.6 0.0 2.8 0.7 5.6 1.9 0.0 0.0 51.1 0.1 3.8 12.4 0.2 0.5 0.0 4.0 14.3 6.3 0.0 0.0 0.0 0.4 0.2 12.4 0.8 0.0 12.8 0.2 13.8 0.0 2.2 0.3 0.1 0.0 0.1 4.3 0.3 1.8 0.0 3.2 7.5 0.0 0.3 0.0 0.0 17.4 6.5 0.0 0.3 11.0 1.5 17.9 16.5 6.7 19.1 3.4 0.5 2.9 0.8 0.1 56.5 15.9 1.5 2.0 0.6 0.5 0.1 0.0 0.5 0.3 31.0 0.2 0.0 5.1 44.2 1.9 0.0 0.0 1.0 0.4 23.9 0.0 0.8 3.1 3.9 17.4 13.2 9.7 5.0 2.2 0.0 1.8 0.0 0.0 9.8 1.2 6.4 40.9 41.8 154.9 1.8 0.4 0.0 1.8 21.8 78.9 37.7 11.1 0.0 3.7 0.0 12.5 0.4 32.8 0.1 0.0 0.0 33.9 0.9 19.8 6.0 22.9 3.4 491.3 0.0 0.2 13.5 1.1 1.1 0.0 31.6 0.7 1.2 1.8 47.1 300.7 0.5 0.0 9.2 18.2 38.5 10.8 16.5 14.2 66.5 5.2 6.8 0.0 211.6 46.7 0.0 0.1 21.1 0.8 14.3 0.1 1.9 0.0 1.7 0.0 1.1 8.5 10.5 9.8 0.0 1.3 0.1 6.1 5.7 0.6 0.3 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 118.3;Proximal tubular cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.4;intermediate monocyte: 16.7;memory B-cell: 5.4;myeloid DC: 7.6;non-classical monocyte: 11.0;plasmacytoid DC: 5.1" "Group enriched" "Detected in all" 5 "B-cells: 5.4;dendritic cells: 7.6;monocytes: 16.7" "Cell line enhanced" "Detected in all" "Hep G2: 186.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 14.6 7.6 52.8 11.7 76.1 10.8 65.5 67.3 66.2 15.2 35.5 15.8 17.9 15.3 13.9 18.7 22.9 19.0 22.5 52.6 60.5 88.8 173.2 27.1 12.0 74.4 71.3 31.9 59.3 9.1 9.1 26.7 66.8 28.3 18.8 4.0 38.7 18.4 19.2 32.9 15.5 13.4 56.6 14.6 22.1 13.2 68.6 8.9 15.0 14.4 13.4 13.2 19.0 114.8 21.3 29.4 25.4 23.3 27.9 32.5 13.7 29.8 16.8 20.4 24.5 31.5 17.2 65.8 19.2 22.8 11.9 17.8 43.5 26.0 28.5 41.9 34.6 53.2 35.2 186.5 24.4 44.4 26.2 43.8 26.9 23.9 31.0 33.5 38.8 19.6 54.7 22.4 16.0 20.9 34.0 67.2 20.9 51.1 49.8 38.3 25.9 79.2 27.9 19.3 56.2 41.5 25.5 75.5 24.4 25.1 22.8 42.3 19.3 31.2 20.5 19.9 21.4 33.8 24.2 68.0 25.7 21.5 8.2 1.7 6.4 0.8 0.7 16.7 1.2 5.4 1.1 1.2 7.6 2.1 0.6 0.6 1.8 1.9 11.0 5.1 1.1 1.8 52.8 76.1 67.3 66.2 52.6 60.5 74.4 71.3 66.8 56.6 68.6 114.8 17.9 16.0 16.0 0.7 9.7 26.4 19.8 11.5 79.6 1.2 44.7 34.3 13.2 58.6 12.1 64.4 4.2 12.9 2.1 15.1 17.6 11.5 0.2 21.3 14.5 16.7 13.1 11.3 7.7 8.5 11.2 18.6 23.9 23.8 2.5 9.5 17.9 118.3 10.1 1.7 4.0 26.8 10.2 20.9 20.7 2.7 22.4 21.9 30.2 6.5 8.8 1.6 2.1 3.0 74.2 7.8 27.6 21.8 25.4 15.7 17.8 105.8 14.7 1.7 0.0 15.2 18.1 1.5 13.3 52.1 41.1 11.5 4.3 21.6 30.6 14.5 AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" 44.1 50.3 26.6 30.2 28.5 132.3 44.3 27.1 32.4 34.6 44.0 29.3 11.2 24.7 47.7 53.6 48.3 25.2 37.0 24.5 30.5 65.8 29.5 62.3 23.4 37.3 28.8 26.9 67.3 25.7 31.2 22.0 31.3 79.1 9.3 3.4 39.0 21.0 54.3 38.8 25.7 20.3 28.4 83.4 33.7 24.7 31.8 11.3 40.8 12.4 13.3 43.9 43.3 31.1 55.9 66.7 16.7 36.9 27.5 34.9 30.5 28.6 49.0 34.8 30.2 42.0 129.7 5.4 126.7 35.4 87.3 45.8 27.9 135.3 10.7 3.1 61.5 1.6 38.4 51.8 84.9 27.6 64.3 34.6 105.4 112.9 59.2 42.4 46.9 17.3 73.8 52.8 19.8 44.6 13.7 80.9 29.7 24.0 67.3 4.6 15.0 27.5 56.7 5.2 14.6 22.0 52.5 26.4 48.4 22.3 59.8 57.4 26.0 44.1 30.8 70.3 30.9 19.6 24.2 33.3 111.7 196.1 20.7 483.4 844.2 694.6 185.7 442.7 90.4 47.0 66.9 109.8 312.2 38.2 72.0 93.5 756.8 73.0 385.2 25.5 90.8 577.4 26.6 28.5 27.1 32.4 24.5 30.5 37.3 28.8 31.3 28.4 31.8 31.1 46.2 22.4 27.4 3.9 12.1 11.6 30.7 112.4 16.5 1.0 54.8 56.0 12.0 32.9 41.6 36.8 6.2 15.7 60.1 6.9 9.8 95.5 20.6 75.3 30.8 36.1 7.2 21.0 0.2 446.7 92.4 45.3 11.2 41.1 88.0 19.1 42.1 7.7 118.3 3.3 0.2 12.3 20.3 143.5 18.9 23.4 37.9 97.8 28.4 1.9 107.4 19.4 122.6 0.5 7.0 96.9 22.5 27.1 8.6 66.5 8.6 55.3 78.5 5.6 13.1 13.0 23.8 3.5 36.1 34.4 13.5 13.1 45.0 50.4 18.2 25.2 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AIF1L "C9orf58, FLJ12783, IBA2" ENSG00000126878 "Allograft inflammatory factor 1 like" Q9BQI0 9 131096476-131123152 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.4;kidney: 313.2;lymphoid tissue: 206.8" "Group enriched" "Detected in many" 4 "Adipocytes: 122.9;Collecting duct cells: 356.8;Distal tubular cells: 289.5;Extravillous trophoblasts: 383.2;Proximal tubular cells: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 140.3;MCF7: 96.7;NTERA-2: 106.7;RPTEC TERT1: 299.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020522, HPA056852" Enhanced NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA020522: AB_2670463, HPA056852: AB_2683256" "unprognostic (2.59e-2)" "unprognostic (1.83e-3)" "unprognostic (2.55e-2)" "unprognostic (2.81e-2)" "unprognostic (1.78e-2)" "unprognostic (2.01e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.77e-1)" "unprognostic (4.39e-1)" "unprognostic (2.81e-2)" "unprognostic (2.68e-1)" "prognostic favorable (5.54e-6)" "unprognostic (2.48e-2)" "unprognostic (2.37e-1)" "unprognostic (1.38e-2)" "unprognostic (6.20e-2)" 44.7 4.8 165.6 4.7 199.6 2.3 39.9 179.6 284.4 20.2 101.5 7.2 1.3 13.5 9.3 105.8 10.8 8.3 41.8 145.4 160.9 313.2 1.6 12.2 1.9 209.2 204.2 5.1 6.5 80.6 18.2 23.8 196.2 6.6 5.7 6.9 32.1 36.6 14.6 15.9 7.9 10.0 172.9 206.8 9.0 6.5 188.0 3.9 91.9 21.9 5.8 9.2 35.3 225.1 0.5 2.2 140.3 24.1 0.0 0.0 59.5 0.0 0.3 0.1 0.3 26.8 11.3 0.0 63.5 0.0 3.0 13.5 21.2 1.5 0.8 0.3 30.0 15.7 7.4 51.4 0.3 0.1 7.6 1.2 6.6 0.5 0.7 0.4 6.7 39.3 10.6 0.1 0.0 96.7 9.3 1.9 106.7 9.0 10.1 0.2 1.9 39.6 299.9 8.5 54.3 8.7 7.4 60.0 20.4 82.7 57.6 0.9 0.9 3.8 10.2 0.5 30.8 0.4 0.5 0.4 6.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 165.6 199.6 179.6 284.4 145.4 160.9 209.2 204.2 196.2 172.9 188.0 225.1 122.9 0.0 0.0 5.9 2.8 4.1 2.1 1.5 1.2 0.1 45.0 29.5 6.6 0.0 3.5 356.8 0.0 4.5 1.3 0.8 289.5 1.5 1.0 4.1 3.5 35.0 3.6 0.0 0.3 0.8 383.2 15.5 0.5 15.0 0.0 10.1 33.5 0.0 7.0 0.0 0.3 2.1 2.0 0.3 2.0 3.5 37.6 2.3 67.6 21.5 0.0 15.1 0.0 8.0 36.3 2.9 0.3 59.0 0.0 7.7 0.0 201.5 0.6 0.2 0.0 3.3 10.3 0.2 5.3 4.4 2.4 21.1 1.7 29.9 1.3 2.0 AKNA KIAA1968 ENSG00000106948 "AT-hook transcription factor" Q7Z591 9 114334156-114394405 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 148.0;dendritic cells: 240.0;NK-cells: 265.7;Plasma cells: 137.3;Rod photoreceptor cells: 140.1;T-cells: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 108.4;MOLT-4: 98.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052367, HPA063993" Supported Nucleoplasm,Centrosome NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Centrosome" "HPA052367: AB_2681801, HPA063993: AB_2685169" "unprognostic (5.19e-3)" "prognostic favorable (1.22e-4)" "unprognostic (5.38e-3)" "prognostic favorable (2.14e-5)" "unprognostic (3.12e-1)" "prognostic favorable (1.25e-4)" "unprognostic (1.88e-1)" "unprognostic (3.28e-2)" "unprognostic (4.13e-2)" "unprognostic (6.62e-2)" "unprognostic (5.85e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.19e-2)" "unprognostic (6.61e-3)" "unprognostic (2.93e-1)" "prognostic favorable (2.29e-4)" 23.3 8.5 13.1 54.5 14.3 50.6 18.9 12.9 14.9 49.6 21.0 20.5 16.2 37.2 5.8 8.8 37.4 14.6 8.4 11.1 14.5 10.3 19.2 32.0 82.4 22.7 21.2 28.0 10.4 2.9 11.4 8.5 17.2 16.9 11.9 36.0 9.2 11.0 3.0 7.7 52.5 22.6 16.3 110.6 21.4 7.8 15.2 75.2 11.5 3.6 61.6 17.6 18.3 14.1 4.7 4.8 5.9 3.7 36.9 4.4 25.1 5.0 6.2 4.8 4.0 7.8 4.9 57.9 4.7 4.3 8.2 10.7 3.7 1.4 1.3 108.4 2.3 6.0 2.4 5.6 42.2 57.5 59.5 8.0 8.1 4.0 3.8 6.7 8.7 49.9 5.3 61.9 2.0 7.5 98.0 63.2 20.1 10.2 5.8 60.4 1.0 12.8 40.3 2.3 2.7 5.2 1.3 4.0 13.4 6.3 11.5 29.2 14.2 2.2 4.8 0.8 4.2 12.5 15.4 47.0 2.8 27.6 2.2 11.5 7.9 12.6 18.9 5.7 14.8 7.6 10.3 16.9 5.0 7.9 9.0 12.1 19.6 14.6 5.5 10.5 8.7 10.3 13.1 14.3 12.9 14.9 11.1 14.5 22.7 21.2 17.2 16.3 15.2 14.1 13.5 12.8 22.8 2.6 76.0 5.2 6.9 1.6 6.2 36.4 7.4 5.3 4.1 4.3 8.3 23.9 148.0 9.5 240.0 9.5 0.0 3.7 17.5 34.8 14.4 9.7 12.7 34.3 2.6 8.1 6.2 8.8 17.9 12.4 33.5 16.6 12.1 9.6 18.2 5.0 8.4 18.9 2.0 59.1 31.5 26.2 14.6 43.0 5.4 19.7 67.2 7.0 265.7 20.1 4.9 5.4 9.2 6.8 137.3 7.8 12.6 0.9 40.7 140.1 0.0 5.8 13.6 1.1 0.9 1.9 3.4 3.4 145.7 2.8 13.4 9.3 AKTIP "FLJ13258, FTS" ENSG00000166971 "AKT interacting protein" Q9H8T0 16 53491040-53504411 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 168.3;Late spermatids: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041794, HPA046300" Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA041794: AB_2677677, HPA046300: AB_2679619" "unprognostic (2.08e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-2)" "unprognostic (5.44e-2)" "unprognostic (2.62e-2)" "unprognostic (9.90e-2)" "unprognostic (1.72e-2)" "unprognostic (3.41e-3)" "unprognostic (2.45e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "prognostic favorable (1.18e-14)" "unprognostic (2.39e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-1)" "unprognostic (1.31e-1)" 29.3 20.5 46.9 15.7 48.9 32.1 24.7 47.8 55.7 24.5 42.0 30.2 15.5 22.3 31.6 33.2 21.4 17.4 55.3 50.9 47.2 37.1 31.8 24.4 22.5 51.5 46.9 30.4 17.3 44.9 29.0 30.2 52.8 24.7 17.8 76.9 20.5 31.0 134.9 26.9 20.0 25.7 47.6 15.5 21.2 44.0 47.5 13.2 31.7 81.4 24.2 25.1 26.1 48.9 40.2 25.7 17.2 22.7 22.8 17.2 50.5 24.7 18.6 21.5 5.3 35.0 20.6 6.6 14.9 25.4 16.2 34.0 14.9 20.0 28.8 9.7 23.6 1.9 13.6 28.1 29.6 9.2 17.1 14.6 55.1 21.4 18.4 31.2 37.1 13.4 3.6 14.1 19.2 31.2 8.0 13.7 11.9 19.2 24.6 9.6 28.5 30.3 28.4 33.2 13.5 16.8 14.9 52.4 22.4 22.9 46.7 5.7 35.2 23.1 25.1 15.2 24.4 20.6 19.6 13.5 24.9 8.1 15.0 22.3 4.5 11.0 32.4 3.4 19.5 9.1 31.1 33.9 2.0 13.7 47.7 39.3 29.3 27.1 3.4 3.0 46.4 19.1 46.9 48.9 47.8 55.7 50.9 47.2 51.5 46.9 52.8 47.6 47.5 48.9 41.9 25.6 15.4 11.8 9.3 7.0 15.1 29.0 5.7 28.4 17.9 11.9 32.2 17.2 25.4 23.9 16.7 80.3 13.6 15.0 82.2 29.8 168.3 11.2 7.1 22.2 6.0 3.6 19.4 20.5 44.3 16.4 8.2 12.9 3.8 9.6 26.0 26.3 13.3 21.9 20.2 6.5 44.7 7.0 5.6 325.9 14.0 6.2 23.2 7.5 8.0 58.8 28.8 8.5 21.5 20.6 6.0 38.4 12.2 15.0 36.2 38.2 22.0 27.3 6.6 22.1 22.2 16.1 40.4 11.2 12.8 77.3 28.7 8.4 11.5 19.0 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 ALS2CL "DKFZp686I0110, FLJ36525, RN49018" ENSG00000178038 "ALS2 C-terminal like" Q60I27 3 46668995-46693704 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.5;kidney: 30.7;skin 1: 32.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Gastric mucus-secreting cells: 41.3;Respiratory ciliated cells: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 31.6;HaCaT: 17.1;HBEC3-KT: 33.1;hTCEpi: 20.9;RT4: 15.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB046465, HPA048301" Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB046465: AB_10638285, HPA048301: AB_2680346" "unprognostic (6.38e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-3)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.86e-2)" "unprognostic (1.04e-2)" "unprognostic (1.92e-1)" "unprognostic (8.60e-2)" "unprognostic (4.28e-2)" "unprognostic (1.42e-2)" "unprognostic (4.50e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-3)" "unprognostic (4.45e-2)" "unprognostic (5.20e-2)" "unprognostic (6.79e-2)" "unprognostic (4.14e-3)" 4.7 2.2 0.8 1.6 0.9 0.8 5.1 1.8 2.0 10.1 0.5 5.6 3.5 2.2 0.1 37.5 4.4 2.7 10.1 0.6 0.8 30.7 7.2 10.8 1.7 1.5 0.6 1.8 5.8 0.5 4.3 1.3 1.4 4.5 1.0 0.0 11.0 2.2 5.3 32.3 4.7 0.8 0.5 6.5 3.5 0.8 0.6 1.1 15.6 1.9 1.4 4.8 19.5 0.6 9.8 2.2 0.0 0.0 0.0 0.0 0.1 0.7 1.1 0.0 0.3 0.1 31.6 0.0 8.9 0.8 0.5 17.1 0.0 33.1 0.1 0.1 0.0 0.8 3.7 0.0 0.3 0.0 0.0 0.0 20.9 0.0 3.2 0.2 0.9 2.0 0.0 0.2 0.0 0.9 0.0 0.1 0.3 4.7 1.9 0.1 0.0 12.0 7.7 15.8 0.3 0.2 12.6 9.7 0.0 0.5 2.2 0.2 6.6 0.1 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.8 0.9 1.8 2.0 0.6 0.8 1.5 0.6 1.4 0.5 0.6 0.6 17.5 73.7 15.3 2.3 0.5 15.2 8.4 21.8 12.0 0.3 4.7 5.5 10.2 18.6 29.9 11.0 0.0 1.5 0.1 29.0 0.0 10.1 0.6 5.1 1.8 13.1 0.0 0.0 8.0 13.5 7.3 4.5 41.3 5.5 1.3 0.1 7.1 7.6 2.7 0.0 2.9 6.4 24.4 0.3 4.1 0.2 0.3 1.4 1.8 10.3 0.8 0.1 0.0 0.0 0.3 26.3 12.0 0.0 0.1 17.7 5.9 0.4 46.9 0.1 19.7 5.6 8.5 1.3 2.7 22.3 16.3 2.1 1.3 0.3 11.8 27.7 AMD1 SAMDC ENSG00000123505 "Adenosylmethionine decarboxylase 1" P17707 6 110874770-110898879 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 202.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 70.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029281, HPA029282" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA029281: AB_10600101, HPA029282: AB_10599965" "prognostic unfavorable (3.87e-4)" "unprognostic (4.68e-2)" "unprognostic (1.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.91e-6)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (6.50e-2)" "unprognostic (2.25e-1)" "unprognostic (4.20e-1)" "prognostic favorable (4.28e-4)" "unprognostic (8.62e-3)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (7.71e-2)" 31.8 28.3 35.0 34.7 44.9 89.9 33.9 39.6 56.1 32.8 32.0 36.9 29.2 35.5 25.7 56.0 25.6 33.3 40.2 37.5 38.2 48.6 33.6 33.4 39.9 45.6 38.5 30.0 39.7 40.3 26.0 59.9 42.2 202.9 36.5 35.9 37.4 34.5 26.7 26.9 26.5 35.4 45.5 27.3 31.2 31.9 37.6 40.5 46.2 50.2 50.3 37.4 25.8 67.1 85.8 57.4 68.6 130.6 101.1 63.9 89.8 119.9 131.8 91.4 106.7 92.2 52.3 149.7 56.7 76.7 97.0 57.4 163.9 108.6 125.1 88.5 94.6 155.4 47.5 96.5 60.2 135.7 88.9 43.4 98.0 63.4 126.4 31.8 81.0 75.4 118.2 126.8 156.3 51.8 181.9 103.3 84.7 84.1 51.9 98.5 68.9 89.3 103.9 112.9 87.4 62.2 73.2 91.7 110.7 55.5 59.5 114.9 53.8 60.5 45.7 325.0 131.5 34.4 59.7 152.8 69.6 106.7 79.4 42.9 23.9 37.7 17.4 28.9 20.2 14.5 17.4 20.3 31.5 14.8 20.4 20.8 102.6 15.5 37.3 13.9 22.5 17.0 35.0 44.9 39.6 56.1 37.5 38.2 45.6 38.5 42.2 45.5 37.6 67.1 169.5 38.5 92.5 23.2 164.8 315.3 241.5 49.5 262.4 101.4 178.5 151.1 95.7 125.8 82.7 55.2 60.5 44.5 208.7 144.1 146.8 67.2 31.8 145.0 106.2 104.4 124.4 184.1 39.2 70.0 152.0 132.1 96.4 214.8 93.9 36.9 53.6 59.3 77.0 77.4 37.9 108.2 28.5 109.1 244.2 53.6 43.8 176.7 131.6 23.4 92.0 303.7 60.8 36.7 111.6 87.6 95.9 50.0 118.9 379.4 66.2 89.9 29.3 105.6 19.7 170.5 124.9 93.0 76.7 246.4 288.1 54.6 184.6 45.7 128.8 147.7 AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 83.5;kidney: 39.8;liver: 37.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 672.6;Intestinal goblet cells: 283.9;Paneth cells: 724.4;Proximal enterocytes: 2014.8;Proximal tubular cells: 348.9;Undifferentiated cells: 272.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.1;Hep G2: 9.9;U-698: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" 1.4 0.0 0.1 1.1 0.2 0.1 0.5 0.1 0.2 1.5 0.0 33.0 43.5 0.1 0.0 5.6 1.1 1.9 0.0 0.2 0.1 39.8 37.8 1.7 0.1 0.3 0.1 0.1 0.7 0.0 0.5 0.0 0.3 0.7 3.0 0.0 1.2 0.0 0.0 2.3 83.5 0.1 0.1 0.5 8.0 0.8 0.1 0.1 0.8 0.0 0.0 0.3 2.5 0.3 0.3 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.1 0.1 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 9.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.7 1.2 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.7 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.3 0.2 9.6 0.5 0.7 18.0 13.4 23.4 1.3 12.0 3.3 13.1 2.0 1.5 140.2 6.1 20.2 0.0 2.7 4.7 672.6 33.2 1.8 4.8 8.2 1.1 0.6 19.2 0.8 0.1 0.7 4.1 0.9 61.7 10.5 4.5 1.9 0.4 52.6 0.6 1.7 0.1 283.9 6.1 1.6 2.3 6.3 0.6 3.1 7.2 0.0 0.1 0.2 1.0 0.0 0.1 11.1 724.4 0.7 4.5 28.1 2014.8 348.9 4.5 1.2 0.0 0.5 0.9 21.2 25.7 17.1 20.9 1.4 5.2 0.4 272.4 65.7 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Group enriched" "Detected in some" 6 "Plasma cells: 43.8;Skeletal myocytes: 13.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "U-266/70: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 0.1 0.1 0.0 0.5 0.0 0.3 3.0 0.0 0.0 0.2 0.0 5.6 16.4 0.2 0.0 5.8 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.0 3.5 5.5 0.0 4.4 0.9 559.2 0.0 7.5 0.1 0.0 1.6 3.7 0.1 0.0 0.4 0.1 211.4 2.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.8 1.9 0.0 0.0 0.0 3.0 4.2 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 28.3;salivary gland: 6.8;stomach 1: 7.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 14.0;Ionocytes: 4.1" "Group enriched" "Detected in many" 11 "cervical cancer: 13.9;head and neck cancer: 38.3;lung cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 16.7;hTERT-RPE1: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036136: AB_2674963, HPA036137: AB_10673614" "unprognostic (1.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-2)" "unprognostic (7.35e-2)" "unprognostic (2.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.3 0.0 0.1 0.3 0.0 0.0 28.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.7 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 23.7 0.1 0.0 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.5 14.0 0.0 0.0 0.1 0.3 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Late spermatids: 75.1;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" 11.3 18.5 18.3 11.8 19.7 6.8 12.7 16.7 21.2 12.8 15.6 10.0 9.2 14.8 23.8 7.0 12.2 11.4 15.7 19.2 21.1 11.6 19.3 14.0 12.2 22.5 19.6 19.3 50.8 17.2 21.1 10.4 21.5 9.3 10.9 26.4 15.8 8.4 12.2 6.4 10.3 12.3 18.1 29.3 15.8 52.4 20.1 8.1 13.7 9.8 10.9 9.5 8.5 23.8 13.1 14.0 15.2 13.6 12.2 11.1 14.1 7.7 11.0 7.8 9.9 13.5 18.2 23.8 11.1 6.7 10.6 16.2 14.6 13.7 13.1 10.1 13.1 14.8 9.7 10.3 7.9 7.8 8.7 11.8 16.8 7.3 14.5 11.3 20.0 24.8 14.5 6.2 8.2 25.3 14.0 11.6 17.5 20.7 18.4 17.0 10.4 14.1 11.8 18.4 21.5 9.6 11.6 15.8 7.1 13.8 31.1 8.4 9.6 9.1 8.0 6.9 6.4 15.9 12.9 14.7 7.7 13.7 11.8 0.8 4.8 1.6 5.9 5.5 7.2 6.8 5.3 5.6 7.5 5.5 7.5 5.6 1.4 5.5 7.1 4.9 4.5 5.9 18.3 19.7 16.7 21.2 19.2 21.1 22.5 19.6 21.5 18.1 20.1 23.8 7.4 6.4 10.5 17.6 4.7 1.1 1.8 1.5 2.2 2.4 5.7 5.0 6.7 5.7 2.2 3.7 10.4 1.5 1.5 2.1 0.0 3.3 64.3 3.7 3.9 10.0 4.2 4.2 18.3 3.2 2.8 4.3 1.5 3.3 1.3 15.9 7.1 9.5 7.2 0.0 19.7 4.4 4.1 5.7 2.0 75.1 2.1 5.5 1.8 23.4 1.4 4.9 1.0 64.8 30.2 2.5 1.0 4.9 8.9 3.4 1.7 1.3 1.4 8.9 6.6 5.1 2.4 15.9 4.9 2.8 0.4 1.2 3.0 12.9 4.6 1.5 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 209.6;Leydig cells: 61.8;Peritubular cells: 78.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.1;RT4: 17.7;U-266/84: 25.4" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" 3.6 9.0 5.1 2.6 4.5 2.7 1.5 2.0 5.4 2.3 0.1 1.3 1.2 2.2 1.9 3.6 4.0 2.9 2.2 3.8 2.5 0.8 0.4 2.6 4.8 4.7 2.7 3.8 4.4 4.4 1.2 1.6 2.2 2.3 0.4 2.8 2.4 2.1 1.2 3.3 1.8 1.6 2.1 10.7 1.7 3.6 3.5 0.8 2.6 0.1 1.3 3.0 2.0 2.5 1.2 3.7 1.6 1.6 2.7 2.1 6.9 1.6 4.4 1.7 2.5 2.1 1.7 1.6 1.9 3.8 1.4 1.3 3.7 0.3 1.4 0.7 1.1 1.5 4.6 1.5 2.0 1.2 2.5 1.6 0.5 1.1 0.6 0.9 1.2 1.7 0.3 24.1 0.5 3.5 0.6 2.6 2.2 0.6 1.7 0.8 1.0 12.1 0.2 17.7 3.2 4.5 1.0 1.2 1.8 1.5 1.2 1.5 1.8 3.2 3.3 2.8 1.6 6.4 25.4 1.2 3.6 3.0 1.0 0.5 0.4 0.0 1.0 0.9 0.3 0.4 0.5 1.4 0.7 0.3 0.3 0.4 0.7 3.1 0.9 0.0 2.1 0.4 5.1 4.5 2.0 5.4 3.8 2.5 4.7 2.7 2.2 2.1 3.5 2.5 8.0 0.0 1.3 209.6 1.5 5.6 4.2 1.1 4.0 11.2 0.7 1.0 1.4 1.5 1.3 0.0 12.5 3.1 3.8 0.1 0.0 0.9 1.1 1.7 9.6 12.7 1.2 0.0 37.7 2.3 5.6 6.5 0.0 3.6 5.7 1.1 5.3 0.0 5.4 3.3 24.6 0.0 2.0 6.0 25.4 4.1 61.8 7.1 10.6 19.7 1.1 28.9 5.2 30.2 10.7 2.8 0.1 78.6 6.2 2.7 0.0 0.3 0.2 8.2 13.1 11.8 7.1 2.6 1.3 0.8 3.7 2.2 3.0 3.3 0.1 5.2 ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 160.1;Hofbauer cells: 208.8;Inhibitory neurons: 214.5;Oligodendrocytes: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" 9.9 10.6 22.1 6.6 23.8 8.0 9.9 33.9 29.3 5.5 26.6 12.8 16.8 7.1 4.9 7.4 7.7 9.4 32.2 22.5 25.5 8.1 21.4 7.1 8.5 25.3 28.2 16.0 15.2 19.2 22.8 8.5 25.1 32.7 11.4 25.1 14.3 9.2 40.9 20.3 15.0 8.5 24.9 6.8 7.3 1.9 26.8 11.5 10.7 37.6 14.1 7.3 7.4 28.8 7.2 5.4 6.7 1.1 13.8 32.3 3.2 6.8 13.7 2.6 2.7 4.3 9.0 16.9 15.7 9.4 6.2 4.6 4.6 7.5 3.0 6.7 11.3 0.4 47.8 11.6 4.6 4.1 1.3 10.2 13.0 8.1 9.2 9.2 5.5 12.3 3.5 35.2 8.7 9.6 6.9 13.3 2.6 9.5 6.0 9.8 3.3 15.3 0.0 2.3 16.4 4.5 33.3 5.3 7.5 6.1 0.3 1.5 5.4 6.9 6.9 11.5 12.6 9.2 9.3 13.0 23.8 15.1 29.0 0.6 0.2 0.0 1.4 0.4 2.3 1.5 2.9 2.3 0.3 1.6 3.3 1.5 0.3 0.3 0.9 0.3 4.6 0.4 22.1 23.8 33.9 29.3 22.5 25.5 25.3 28.2 25.1 24.9 26.8 28.8 50.1 25.6 19.1 64.6 15.4 25.2 79.1 33.7 40.9 58.0 29.7 15.5 73.4 7.2 10.8 7.3 127.2 76.4 21.1 58.2 5.9 1.7 1.2 7.1 14.9 25.4 41.8 69.9 160.1 11.8 6.1 25.6 8.2 16.9 17.7 9.8 12.5 32.7 208.8 20.2 214.5 37.7 8.2 89.3 29.9 1.9 5.0 42.6 10.6 106.8 3.4 20.1 21.6 95.5 261.5 6.8 31.4 31.6 14.7 55.4 44.6 10.2 6.4 50.1 0.0 32.8 12.3 2.3 7.2 10.1 10.7 42.0 25.9 8.6 37.3 22.3 ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 153.3;Microglial cells: 390.7;NK-cells: 146.2;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.4;HMC-1: 33.8;Karpas-707: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" 5.8 6.4 8.0 24.6 10.8 17.4 4.1 8.9 9.3 8.1 5.7 5.8 3.8 4.9 2.8 3.2 3.8 8.4 4.2 6.8 10.4 3.3 4.9 11.6 36.5 12.7 10.8 3.2 3.7 4.1 3.9 7.6 13.2 4.4 5.5 3.3 4.0 5.0 2.2 3.6 11.5 6.1 10.0 23.0 6.8 5.7 11.7 28.3 3.2 2.2 33.2 6.8 6.2 14.6 1.9 1.1 2.8 2.9 6.2 2.5 0.6 4.1 1.8 2.1 1.9 0.7 1.0 15.4 1.9 3.5 3.9 0.2 1.0 0.8 1.7 46.4 3.7 0.5 5.6 0.3 0.4 11.4 33.8 1.3 0.5 2.1 0.1 3.1 2.9 3.8 2.6 25.1 3.2 2.6 5.4 9.7 0.4 0.6 2.8 9.7 3.1 20.3 5.4 1.4 2.8 12.2 1.4 1.0 12.0 2.1 1.5 11.0 15.0 7.1 4.2 2.2 3.0 6.2 8.0 19.6 5.0 14.0 4.5 55.0 19.6 45.3 24.5 19.5 23.3 23.5 18.2 21.3 19.2 28.6 20.9 25.2 68.7 25.0 25.2 12.6 19.0 15.1 8.0 10.8 8.9 9.3 6.8 10.4 12.7 10.8 13.2 10.0 11.7 14.6 8.4 16.0 23.9 79.7 153.3 3.4 4.5 0.4 2.2 9.9 4.4 3.9 9.3 20.0 8.0 11.0 4.2 5.9 90.6 0.6 1.9 4.0 14.0 10.7 6.7 10.2 2.4 12.8 32.6 4.6 0.8 9.7 8.2 15.5 53.8 4.8 49.2 8.9 18.5 3.3 126.4 1.9 0.0 64.2 34.9 17.5 15.5 72.5 37.4 390.7 84.1 8.0 146.2 174.9 199.5 5.0 2.6 17.7 70.4 3.9 2.9 1.5 10.6 10.4 19.7 15.5 16.4 2.9 3.4 5.2 3.7 1.4 123.0 4.3 1.8 4.9 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO7 "IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G" ENSG00000146205 "Anoctamin 7" Q6IWH7 2 241188509-241225377 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.3;prostate: 69.6;stomach 1: 28.1" "Group enriched" "Detected in many" 5 "Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 53.4" "Cancer enriched" "Detected in many" 19 "prostate cancer: 32.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.2;Hep G2: 2.3;OE19: 2.5" "Low region specificity" "Detected in many" HPA078464 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA078464: " "unprognostic (1.93e-2)" "unprognostic (3.45e-3)" "unprognostic (1.09e-3)" "unprognostic (5.13e-2)" "unprognostic (1.35e-2)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (8.45e-2)" "unprognostic (2.90e-2)" "unprognostic (4.94e-2)" "unprognostic (4.82e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.53e-2)" 0.3 0.3 0.2 1.0 0.7 3.6 0.2 0.2 1.0 0.3 0.0 16.3 10.7 0.5 0.0 0.2 0.3 0.0 0.2 0.2 0.2 0.2 0.1 0.1 0.0 1.2 0.2 0.5 0.4 0.0 0.2 0.1 0.4 69.6 10.1 0.0 4.9 0.2 0.0 0.2 14.7 0.1 0.3 0.3 28.1 0.2 0.8 0.0 0.2 0.0 0.0 0.2 0.2 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.2 1.0 0.2 0.2 1.2 0.2 0.4 0.3 0.8 1.6 1.2 0.0 0.0 1.6 0.7 0.3 0.8 0.8 1.2 0.2 1.9 2.7 1.6 0.0 0.2 0.0 0.0 0.6 0.1 2.6 0.0 2.7 0.1 0.8 0.7 2.1 3.0 0.0 4.8 4.2 5.6 2.0 80.0 1.9 0.0 12.4 2.9 3.9 1.5 0.0 2.7 53.4 0.0 1.3 0.0 0.0 3.4 0.7 1.8 7.5 0.0 1.4 0.0 1.0 6.9 6.4 1.9 2.2 0.5 11.9 3.6 2.8 0.0 0.6 0.0 0.8 1.0 0.1 1.7 0.1 0.0 0.7 0.3 2.6 2.4 0.8 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 337.7" "Cell type enhanced" "Detected in many" "Adipocytes: 322.7;Alveolar cells type 1: 589.7;Ductal cells: 434.5;Exocrine glandular cells: 305.3;Pancreatic endocrine cells: 754.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 320 "neutrophil: 207.7" "Lineage enriched" "Detected in single" 327 "granulocytes: 207.7" "Cell line enhanced" "Detected in many" "A-431: 419.5;CACO-2: 403.5;CAPAN-2: 563.7;EFO-21: 334.7;hTERT-HME1: 566.3;OE19: 502.1;RPTEC TERT1: 477.8" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 52.9 3.1 16.5 22.7 17.3 337.7 43.8 14.5 28.2 19.6 11.7 27.7 15.8 12.5 3.7 55.2 16.8 17.3 51.2 14.2 21.6 24.9 3.9 144.4 2.4 19.9 16.1 2.5 32.7 34.0 5.9 81.5 20.8 68.0 26.7 1.6 119.5 12.9 28.3 10.0 13.3 20.1 14.6 21.6 90.5 1.9 19.9 7.1 83.7 36.7 12.7 10.2 15.6 14.7 419.5 77.7 1.3 0.9 1.0 0.9 0.6 4.9 0.4 11.0 10.9 403.5 563.7 0.1 334.7 14.4 0.4 161.6 0.1 300.0 16.0 1.4 3.3 36.4 142.0 23.9 45.9 5.9 0.2 2.4 262.6 4.1 566.3 60.1 118.9 9.0 0.7 0.3 1.9 15.9 1.7 0.2 13.0 502.1 55.4 0.0 0.8 0.0 477.8 45.2 0.3 0.3 235.5 58.2 16.6 186.1 9.9 4.3 153.2 0.6 52.6 0.2 93.0 3.1 5.1 2.2 0.0 0.4 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 207.7 0.1 0.6 0.1 0.0 2.9 16.5 17.3 14.5 28.2 14.2 21.6 19.9 16.1 20.8 14.6 19.9 14.7 322.7 589.7 47.3 0.0 1.1 24.9 81.8 144.9 1.8 0.2 27.6 85.9 8.6 55.8 175.2 38.6 0.0 212.6 1.0 35.4 17.6 434.5 1.1 33.7 4.4 84.6 5.4 3.2 0.9 305.3 106.2 16.9 99.9 58.1 5.1 0.1 23.2 0.6 18.9 0.0 0.3 33.4 122.1 0.3 0.3 0.3 3.1 6.9 5.4 42.2 21.0 1.2 0.0 1.0 0.6 754.2 61.6 0.4 0.6 158.6 11.5 5.5 89.6 0.4 0.0 7.6 18.7 1.1 0.6 21.9 6.7 62.8 2.3 1.3 29.7 46.7 ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 343.8;monocytes: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 861.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" 292.9 135.4 98.1 164.2 104.1 109.7 188.3 94.0 150.6 148.9 151.8 196.0 44.5 181.5 105.0 94.7 149.9 108.7 188.7 102.5 123.1 82.6 214.4 131.6 161.8 144.2 109.4 181.7 78.3 29.6 161.9 141.1 146.2 124.9 78.2 133.6 70.3 208.6 331.3 62.7 119.9 300.1 92.3 150.9 111.4 52.5 127.4 160.8 86.7 371.5 176.4 206.5 107.4 104.8 3.0 30.4 212.8 317.1 861.2 417.8 55.1 397.4 526.4 323.5 477.6 106.7 15.6 26.9 138.5 578.6 268.1 0.5 165.9 200.2 300.3 110.5 52.1 15.3 62.1 204.7 295.0 97.6 94.7 508.6 1.5 282.3 42.0 476.9 420.6 197.5 22.0 396.1 737.6 100.4 181.8 151.7 56.2 1.2 92.4 120.4 592.9 31.0 42.2 0.3 12.2 49.3 39.9 282.7 175.6 308.4 488.3 201.1 326.8 296.6 84.2 19.4 107.1 205.4 289.5 4.5 154.5 459.7 46.2 89.7 89.4 82.9 290.4 54.7 190.4 175.4 213.4 263.3 118.3 179.0 145.8 181.6 17.6 261.9 25.0 30.2 190.9 331.7 98.1 104.1 94.0 150.6 102.5 123.1 144.2 109.4 146.2 92.3 127.4 104.8 90.3 16.0 17.3 19.2 146.8 11.0 11.5 2.2 1.8 16.5 30.7 24.0 59.5 12.8 1.1 23.9 6.2 64.3 110.3 0.3 25.4 6.5 56.9 1.8 38.5 45.6 21.4 36.4 36.5 17.8 33.7 105.9 9.2 1.7 57.5 343.8 57.1 147.1 85.4 15.2 36.3 2.4 0.0 41.0 77.8 46.8 123.3 41.2 55.2 10.3 445.2 45.6 187.4 18.6 5.6 12.1 1.2 211.4 120.3 7.3 1.0 48.4 4.7 125.8 230.1 55.3 150.6 2.5 1.5 0.6 8.1 177.2 143.4 149.4 2.5 1.5 ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Astrocytes: 38.8;Club cells: 40.7;Excitatory neurons: 47.8;Fibroblasts: 34.5;Inhibitory neurons: 41.0;Microglial cells: 35.6;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 48.1;Squamous epithelial cells: 63.6" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 394.3;HBEC3-KT: 622.3;hTCEpi: 357.6;hTERT-HME1: 134.2;RT4: 159.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" 73.3 0.7 0.5 0.1 0.5 0.7 11.7 0.7 1.1 49.6 0.6 0.5 0.0 0.1 1.0 217.6 3.7 0.4 4.4 0.6 0.3 0.0 1.8 13.1 0.0 1.0 0.8 1.3 0.3 0.0 0.3 30.9 0.8 12.4 0.1 0.0 47.3 9.8 0.4 266.2 0.2 0.0 0.6 0.2 0.4 0.8 1.5 4.8 0.2 0.2 46.6 66.4 110.7 0.9 123.4 16.2 0.0 0.0 0.0 0.0 33.7 2.3 0.3 0.0 0.0 8.7 35.0 0.0 2.5 1.0 1.8 394.3 0.0 622.3 0.0 27.9 0.0 0.0 39.6 0.0 26.2 0.0 1.3 0.2 357.6 0.2 134.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 37.2 0.1 4.0 0.0 0.0 0.5 0.0 0.0 159.6 0.0 0.0 56.4 16.4 0.3 8.7 0.1 3.5 0.0 0.0 39.5 0.7 2.4 0.2 0.1 0.2 4.4 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.5 0.7 1.1 0.6 0.3 1.0 0.8 0.8 0.6 1.5 0.9 0.1 99.3 7.3 38.8 0.0 1.1 10.3 1.6 2.8 0.0 4.9 3.4 2.6 7.2 40.7 3.7 0.0 14.7 0.1 1.0 0.0 3.1 0.6 2.1 0.0 0.5 0.0 0.0 47.8 0.4 6.7 34.5 0.0 0.2 1.3 0.1 0.0 0.0 0.6 0.0 41.0 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 35.6 0.1 0.0 0.0 50.8 48.1 17.3 0.0 0.0 0.0 8.5 1.5 0.0 14.2 0.0 0.0 0.0 0.6 0.2 1.4 63.6 2.0 6.2 0.3 0.1 0.2 17.2 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;dendritic cells: 9.6;Hofbauer cells: 4.9;monocytes: 10.5;NK-cells: 6.2;T-cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HDLM-2: 2.7;Karpas-707: 6.9;U-266/70: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" 0.7 0.8 0.3 2.3 0.5 3.6 0.6 1.0 0.7 0.7 0.0 1.8 0.5 0.8 3.6 1.1 1.3 1.6 0.5 0.3 0.3 0.8 0.6 2.4 3.8 0.7 0.4 0.5 0.3 0.6 0.7 1.0 0.6 0.7 3.3 0.6 0.9 1.5 0.6 0.5 1.2 1.2 0.2 3.1 0.9 1.6 0.5 2.9 0.7 0.0 2.1 1.4 0.6 0.5 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.2 0.0 0.0 0.2 2.8 1.0 0.3 0.0 0.1 0.0 0.6 0.0 2.7 0.3 0.7 0.1 0.0 0.2 0.0 2.0 1.8 1.6 0.2 0.2 0.2 0.0 0.1 0.0 6.9 0.9 0.9 1.4 0.2 0.0 0.0 0.0 1.6 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 4.8 0.7 0.2 0.2 1.2 0.1 0.1 0.3 0.0 23.2 0.5 9.4 1.4 12.1 19.4 0.2 0.4 0.6 8.9 0.0 19.7 1.6 0.0 11.9 4.7 0.3 0.5 1.0 0.7 0.3 0.3 0.7 0.4 0.6 0.2 0.5 0.5 0.4 0.0 4.2 0.0 1.6 0.1 0.6 0.9 1.2 0.0 0.2 0.3 0.1 0.0 2.4 0.0 0.0 6.6 9.6 0.1 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.1 3.8 0.1 0.4 0.2 4.9 0.0 0.2 0.0 2.0 1.0 0.6 0.5 0.0 1.0 0.0 0.0 10.5 0.0 6.2 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.9 0.1 0.2 0.2 0.0 1.5 20.8 0.0 0.0 0.5 APOF ENSG00000175336 "Apolipoprotein F" Q13790 12 56360568-56362857 "Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 344 "liver: 416.7" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 341.9" "Cancer enriched" "Detected in some" 6 "liver cancer: 34.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 18000000000 2200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (8.99e-3)" "unprognostic (9.84e-2)" "unprognostic (3.29e-2)" "unprognostic (2.08e-3)" "unprognostic (7.84e-2)" "unprognostic (4.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.68e-3)" "unprognostic (8.55e-2)" "unprognostic (2.42e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-2)" "unprognostic (2.87e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.3 0.1 0.2 0.2 0.1 0.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 416.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.4 4.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.2 0.7 0.3 0.2 0.0 0.3 0.1 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.3 8.6 0.0 0.0 2.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.4 0.0 16.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 5.0 341.9 0.0 0.0 0.0 0.1 0.0 10.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 171.2;Microglial cells: 112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 177.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925" Approved NA NA 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039688: AB_2676626, HPA043925: AB_2678733" "unprognostic (3.46e-1)" "unprognostic (4.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-2)" "unprognostic (6.66e-3)" "unprognostic (8.43e-2)" "unprognostic (5.50e-2)" "unprognostic (5.71e-3)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "prognostic favorable (7.65e-4)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (9.32e-2)" 34.1 29.2 33.1 18.5 35.9 37.0 35.2 41.0 35.5 33.0 29.8 54.1 38.8 26.3 19.0 23.4 20.7 34.4 16.3 30.6 34.6 20.7 16.1 18.4 22.7 36.5 34.4 28.8 23.8 23.2 19.7 23.1 37.7 38.8 54.7 33.5 22.2 26.9 14.5 66.6 57.6 22.1 33.0 22.9 31.7 36.6 36.5 20.0 16.2 12.8 17.7 16.6 27.8 38.6 15.5 23.2 37.8 22.9 111.9 80.5 27.6 114.4 110.1 40.0 24.3 27.7 11.8 13.5 21.6 177.9 15.3 18.1 19.2 24.6 49.0 6.8 16.6 7.4 11.4 12.4 18.1 5.5 7.4 42.6 22.9 31.6 35.4 77.4 17.2 18.2 8.4 17.5 90.9 20.9 10.6 17.6 27.8 33.1 33.1 8.3 24.9 25.3 33.4 31.9 25.7 48.1 38.4 17.0 19.3 26.6 28.3 10.1 16.7 61.7 14.8 30.4 19.4 15.9 13.7 9.9 39.6 7.3 34.4 0.2 4.7 10.7 1.6 3.7 1.3 0.4 0.6 0.9 3.2 2.8 0.9 1.4 21.1 4.6 6.2 1.0 2.3 1.7 33.1 35.9 41.0 35.5 30.6 34.6 36.5 34.4 37.7 33.0 36.5 38.6 16.0 19.2 13.2 95.3 6.1 12.7 13.0 6.5 12.0 30.6 18.0 14.1 13.2 28.6 10.6 11.0 10.4 19.9 12.1 171.2 5.9 24.2 6.8 33.8 23.0 15.7 30.0 2.5 50.2 18.9 19.0 22.8 15.8 20.7 8.2 46.0 16.4 6.5 30.3 10.1 51.8 40.0 12.2 23.3 8.3 8.6 23.6 18.9 16.0 112.4 10.3 39.9 10.3 91.5 75.1 26.4 38.1 21.8 6.0 29.4 101.5 16.6 56.2 16.2 19.7 18.9 13.2 15.6 23.7 14.3 19.0 23.1 8.0 25.0 17.5 14.2 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "CAB032985: AB_2058811, HPA038156: AB_10697243" "unprognostic (2.32e-1)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "prognostic favorable (2.00e-5)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-3)" "unprognostic (2.50e-1)" "unprognostic (2.96e-1)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.53e-4)" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.32e-2)" "unprognostic (9.48e-3)" 19.8 29.3 31.7 18.6 32.3 22.8 50.7 32.5 35.2 36.3 36.2 36.8 32.9 27.2 34.0 31.4 39.3 23.9 17.9 32.1 31.4 27.0 34.6 24.4 22.4 31.2 31.4 29.4 49.4 46.4 40.7 29.7 31.9 46.6 48.1 28.3 57.7 28.2 15.2 32.8 30.7 27.4 30.9 20.7 50.4 18.3 31.8 25.7 36.9 16.1 32.0 29.2 24.4 33.1 50.4 64.8 38.9 38.5 59.1 53.9 56.1 40.3 107.0 86.2 101.8 62.1 80.3 39.9 16.5 79.3 49.8 68.0 49.4 84.1 70.0 30.9 86.5 22.3 87.7 60.4 71.3 36.2 42.8 60.0 65.7 43.0 98.3 64.2 55.9 38.3 35.3 45.0 55.8 98.9 41.9 41.6 67.2 119.0 71.9 31.7 22.6 37.1 61.9 50.4 50.8 63.2 48.7 204.9 25.9 36.3 86.9 33.0 36.8 35.4 35.7 39.1 30.3 67.3 32.5 24.3 65.4 22.0 43.9 13.0 15.6 9.9 17.9 10.9 17.8 12.1 16.7 14.5 21.3 13.8 16.7 17.1 6.1 21.1 6.7 16.6 18.9 13.9 31.7 32.3 32.5 35.2 32.1 31.4 31.2 31.4 31.9 30.9 31.8 33.1 14.8 6.4 6.4 4.6 20.7 28.0 49.3 48.9 16.5 32.6 59.8 45.1 4.3 40.0 30.5 12.9 29.2 80.1 24.3 56.0 58.7 62.7 31.7 28.1 20.1 19.6 63.0 21.8 8.4 85.4 65.8 23.1 62.2 37.2 31.8 30.3 20.3 21.1 28.1 21.9 7.8 126.6 32.6 10.1 16.4 43.3 20.5 14.4 24.9 5.6 25.2 35.4 18.6 6.6 7.6 59.9 63.4 24.5 28.0 73.3 65.2 34.4 34.7 32.3 26.3 21.6 23.3 41.0 26.2 26.2 32.1 112.5 16.9 40.9 52.6 64.7 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619920-67651708 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 220.0;prostate: 108.5;thyroid gland: 105.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 190.1;Collecting duct cells: 165.5;Glandular and luminal cells: 145.2;Proximal tubular cells: 220.9;Syncytiotrophoblasts: 601.3;Urothelial cells: 165.2" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 2.8 7.3 5.6 2.9 6.1 0.5 4.8 6.9 13.9 17.0 7.9 2.7 3.7 7.0 3.6 16.3 1.8 9.3 3.4 6.3 11.6 64.0 3.8 3.8 0.5 6.4 7.7 18.7 5.0 220.0 45.6 8.8 9.2 108.5 1.4 22.3 17.0 5.8 35.7 2.1 15.3 3.7 5.1 0.9 3.2 3.4 6.5 3.0 105.0 52.6 1.7 17.8 9.9 5.6 8.9 1.5 14.4 9.4 2.1 0.1 20.1 6.7 17.4 20.6 34.5 36.3 4.5 14.6 1.9 4.3 9.4 2.1 58.2 26.8 24.9 0.7 14.6 6.7 2.6 41.9 6.2 1.8 37.8 1.1 33.6 10.2 49.7 1.6 35.4 37.7 19.4 0.1 1.4 4.4 2.5 1.4 27.2 4.0 0.5 0.8 2.0 16.8 16.8 14.3 31.5 12.2 4.2 4.2 6.4 32.9 15.1 1.2 7.3 6.4 15.9 0.7 5.0 1.3 2.4 4.9 12.8 7.5 10.9 0.1 0.4 0.7 0.3 0.1 0.1 0.2 0.1 0.3 0.5 0.7 0.2 0.2 0.6 0.1 0.4 0.0 0.9 1.0 5.6 6.1 6.9 13.9 6.3 11.6 6.4 7.7 9.2 5.1 6.5 5.6 3.9 0.0 5.8 5.5 8.4 8.8 190.1 17.0 7.4 5.2 41.6 28.7 6.3 4.3 20.3 165.5 10.4 86.5 14.6 9.0 37.2 8.4 16.5 75.1 18.7 5.9 36.8 8.8 20.3 3.3 6.2 5.6 37.8 145.2 7.0 23.9 2.9 1.3 14.7 10.1 41.8 24.5 12.2 0.6 3.6 3.2 0.3 9.3 10.6 7.5 0.9 40.5 1.0 9.0 9.2 5.0 5.0 0.4 5.7 95.4 72.8 220.9 3.0 17.6 6.6 6.2 8.9 8.4 3.4 9.7 5.4 601.3 15.1 2.2 8.7 165.2 ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" 84.5 49.2 40.9 38.0 48.3 33.4 61.8 33.4 46.1 71.3 31.2 62.8 25.7 93.7 21.5 75.0 68.4 50.7 112.3 39.1 41.0 41.5 46.2 38.4 30.7 45.7 43.2 46.4 36.5 24.7 36.8 39.0 39.0 64.9 32.6 9.6 46.1 62.6 30.0 65.3 46.7 80.6 38.0 58.4 49.0 15.8 49.8 23.2 44.6 20.5 34.6 107.9 63.4 57.4 23.0 56.7 27.9 39.8 135.4 99.6 32.9 50.3 50.7 45.3 41.2 34.2 29.5 33.1 26.7 102.3 40.7 55.8 22.4 76.0 33.5 23.3 24.6 36.8 27.7 40.4 44.5 31.3 52.3 131.9 46.7 34.5 42.9 46.8 39.1 27.1 24.3 30.3 55.9 82.6 21.2 30.9 72.1 78.5 29.4 25.0 39.9 49.3 42.3 85.2 10.0 31.6 45.8 69.8 19.1 40.1 88.0 35.4 49.1 82.1 25.5 98.7 51.0 32.0 38.2 24.8 77.4 52.0 39.3 27.6 33.0 33.1 26.7 56.9 19.3 14.3 20.8 22.8 32.3 14.7 17.9 20.8 37.3 23.7 72.0 34.1 27.4 24.9 40.9 48.3 33.4 46.1 39.1 41.0 45.7 43.2 39.0 38.0 49.8 57.4 25.2 19.2 18.7 16.6 18.3 8.5 13.4 24.6 10.8 11.9 22.3 24.6 50.2 10.0 18.1 29.5 27.1 25.1 35.2 35.2 3.9 22.2 0.4 17.9 26.9 19.6 19.4 15.3 13.0 27.9 31.0 29.2 31.6 27.6 19.6 21.3 25.7 32.1 30.4 16.8 15.3 36.0 14.2 30.7 8.4 1.7 23.6 19.1 8.8 11.2 28.2 11.0 36.0 23.1 92.3 27.3 19.2 35.3 10.1 11.4 22.4 13.3 10.9 14.2 59.2 28.0 55.9 3.1 3.5 24.7 13.1 16.6 19.9 9.4 21.5 18.7 ARHGAP10 "FLJ20896, FLJ41791, GRAF2" ENSG00000071205 "Rho GTPase activating protein 10" A1A4S6 4 147732063-148072776 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 137.6;Oligodendrocyte precursor cells: 124.7;Peritubular cells: 121.1;Rod photoreceptor cells: 132.9;Sertoli cells: 144.7;Smooth muscle cells: 107.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 80.2" HPA039589 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039589: " "unprognostic (8.57e-3)" "unprognostic (1.34e-1)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (2.79e-1)" "unprognostic (3.41e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (2.57e-2)" "prognostic favorable (8.15e-5)" "prognostic unfavorable (6.26e-4)" "unprognostic (1.54e-1)" "unprognostic (1.02e-3)" "unprognostic (1.09e-2)" 35.0 11.4 4.6 7.0 6.3 3.3 22.6 2.0 7.1 35.1 9.8 47.0 4.9 16.9 9.8 35.7 35.1 13.0 38.7 6.0 2.6 9.7 7.9 15.1 5.8 3.1 4.7 33.4 9.2 16.0 6.2 10.7 3.5 26.0 8.0 14.4 11.1 20.0 38.6 22.2 16.6 13.3 3.6 9.8 26.3 11.8 5.5 11.3 16.9 33.1 6.7 44.2 30.8 4.1 21.0 8.3 4.4 9.2 33.2 45.1 46.0 28.3 23.5 17.9 13.8 21.6 11.8 0.0 4.7 24.4 15.0 10.1 16.4 23.4 21.5 11.4 10.9 7.2 6.2 0.7 51.2 7.1 8.0 23.4 17.9 22.3 19.0 22.7 22.0 6.0 1.0 38.3 32.3 25.5 4.5 0.0 4.1 13.9 4.0 8.1 12.7 24.5 12.3 19.0 10.7 5.1 7.4 29.6 7.9 19.0 3.7 0.6 21.9 16.8 12.9 10.3 13.8 14.2 1.8 0.1 25.5 0.9 15.1 0.0 1.7 16.7 5.3 0.1 10.5 0.0 4.1 6.2 3.0 0.0 1.2 6.0 0.2 5.3 0.1 0.1 5.4 2.4 4.6 6.3 2.0 7.1 6.0 2.6 3.1 4.7 3.5 3.6 5.5 4.1 18.5 3.2 4.1 5.5 1.5 14.4 7.9 7.0 16.5 7.1 13.0 15.4 64.8 5.7 3.5 1.8 43.8 29.0 11.1 0.2 0.0 5.8 13.6 16.3 83.5 11.8 0.0 1.3 63.3 16.0 48.2 45.6 11.2 31.8 1.3 21.7 4.2 13.0 20.9 3.3 26.7 0.4 0.0 6.2 33.7 10.2 137.6 24.2 5.4 46.9 58.4 8.2 8.2 124.7 2.1 14.0 0.1 121.1 3.2 4.5 0.8 15.0 1.3 132.9 144.7 22.7 107.3 4.7 13.3 15.7 10.2 12.7 16.0 9.1 1.1 3.1 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP25 KIAA0053 ENSG00000163219 "Rho GTPase activating protein 25" P42331 2 68679601-68826833 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.8" "Cell type enhanced" "Detected in many" "B-cells: 88.7;granulocytes: 210.8;Microglial cells: 88.1;NK-cells: 103.0;T-cells: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 657.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 66.7;HMC-1: 256.1;NB-4: 47.3;U-266/70: 50.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035346, HPA061395" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Vesicles" "HPA035346: AB_10601116, HPA061395: AB_2684501" "unprognostic (1.13e-3)" "prognostic favorable (7.72e-4)" "unprognostic (2.45e-2)" "unprognostic (4.44e-3)" "unprognostic (8.07e-2)" "unprognostic (1.36e-2)" "unprognostic (1.13e-1)" "unprognostic (6.16e-3)" "unprognostic (2.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.00e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.10e-1)" "unprognostic (4.26e-2)" "unprognostic (3.61e-1)" "unprognostic (4.49e-2)" 11.1 5.2 5.2 38.8 5.4 37.4 8.0 5.6 7.9 6.0 5.1 7.2 6.2 6.7 22.7 4.3 4.7 11.7 6.7 5.2 5.6 7.1 10.1 21.3 71.4 7.6 6.0 16.7 2.1 2.3 3.5 10.7 6.7 5.0 9.6 0.6 5.1 3.8 3.2 6.2 23.3 8.3 7.1 72.8 8.8 2.5 7.0 27.3 5.1 8.4 67.3 11.9 4.7 8.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 20.8 0.5 0.0 0.1 2.5 0.0 20.5 0.0 2.3 0.0 66.7 0.0 0.0 1.0 14.8 256.1 0.2 2.4 0.4 8.1 0.0 0.0 22.2 0.4 23.6 0.0 0.0 17.2 47.3 1.2 0.2 0.0 18.7 4.3 0.8 0.0 5.4 4.1 0.6 0.2 0.0 1.4 1.4 0.0 12.3 3.5 0.1 0.9 0.1 0.5 50.8 29.0 16.8 0.2 33.3 0.3 234.8 60.8 528.7 171.3 75.9 107.0 156.4 76.2 150.0 37.4 100.8 54.2 95.2 657.3 170.6 94.8 52.3 102.0 132.0 5.2 5.4 5.6 7.9 5.2 5.6 7.6 6.0 6.7 7.1 7.0 8.4 14.1 3.2 15.0 0.3 88.7 5.6 12.4 2.9 5.7 0.8 0.7 6.1 1.4 1.5 2.0 0.0 0.0 0.5 35.1 0.1 1.9 0.1 1.8 0.7 0.6 16.6 3.0 11.6 15.5 0.2 0.4 3.5 2.0 0.4 210.8 0.1 15.4 1.0 48.6 0.0 0.9 0.5 2.0 27.3 12.8 3.6 1.5 22.6 1.8 88.1 40.9 0.5 103.0 0.5 0.9 0.0 0.1 2.6 34.7 1.2 0.0 0.2 5.2 0.2 6.6 0.8 2.1 0.6 1.3 2.5 1.4 0.3 53.7 1.8 0.2 2.5 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF25 "GEFT, p63RhoGEF" ENSG00000240771 "Rho guanine nucleotide exchange factor 25" Q86VW2 12 57610180-57617245 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 151.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.8;Leydig cells: 24.8;Peritubular cells: 45.9;Sertoli cells: 26.3;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 59.1;RH-30: 129.7;SH-SY5Y: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052016 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "HPA052016: AB_2681695" "unprognostic (8.43e-2)" "unprognostic (4.24e-3)" "unprognostic (2.13e-3)" "unprognostic (6.95e-3)" "unprognostic (8.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.45e-2)" "unprognostic (2.39e-2)" "unprognostic (4.63e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.20e-7)" "unprognostic (1.41e-2)" "unprognostic (2.03e-1)" "unprognostic (6.82e-3)" "unprognostic (3.22e-3)" 34.4 12.0 30.7 10.7 38.7 0.1 29.1 38.5 72.1 64.5 12.6 151.2 10.3 92.8 44.3 29.6 85.5 23.6 24.6 72.0 21.7 17.7 5.0 21.7 6.2 20.6 21.1 58.2 8.5 9.4 26.4 9.4 20.8 60.6 19.5 13.2 13.9 80.4 11.4 12.0 34.4 68.8 17.3 20.1 45.0 10.6 22.5 2.1 14.1 13.8 4.9 84.3 51.4 40.5 0.8 8.9 41.6 26.1 0.1 0.0 3.3 12.7 37.4 16.5 20.2 5.2 8.1 3.5 10.7 23.4 7.7 0.4 16.2 0.7 13.9 11.7 13.9 7.4 6.1 11.4 11.6 0.2 19.2 11.5 3.5 7.5 1.1 59.1 6.5 2.0 15.5 16.0 12.2 3.0 2.7 0.3 26.5 0.4 0.4 0.0 129.7 0.7 0.7 0.7 24.1 58.7 2.4 1.2 4.8 14.8 4.3 8.9 0.0 14.8 14.0 9.7 4.7 33.5 5.4 0.1 12.4 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 38.7 38.5 72.1 72.0 21.7 20.6 21.1 20.8 17.3 22.5 40.5 5.6 0.0 0.0 8.5 0.0 2.0 1.8 0.2 4.6 17.7 1.8 8.6 11.6 0.0 0.6 0.0 2.1 0.2 0.6 0.0 0.0 0.5 0.2 1.1 20.8 4.4 0.0 0.0 15.3 1.4 0.5 12.6 0.5 0.6 0.0 2.6 6.8 0.0 0.5 8.4 8.5 0.0 0.0 0.0 1.7 1.5 24.8 0.2 0.0 8.4 0.0 5.4 2.1 3.0 1.6 0.3 0.0 45.9 0.3 0.8 0.0 0.4 0.0 2.8 26.3 6.3 38.9 1.4 1.4 0.9 1.1 0.3 0.5 9.6 0.0 0.4 ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 193.9;Granulosa cells: 128.2;Microglial cells: 77.8" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 117.6;HL-60: 153.7;HMC-1: 532.0;JURKAT: 152.7;U-937: 158.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003578 Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA003578: AB_1078203" "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" 44.0 16.2 23.4 30.5 24.4 31.4 23.5 25.0 19.5 10.7 11.6 13.2 7.5 12.9 5.3 7.6 7.0 17.3 32.9 25.2 26.9 6.7 8.5 25.6 41.8 26.8 29.2 16.5 3.9 10.3 6.2 46.9 27.8 7.8 11.1 4.6 8.7 8.8 68.7 6.2 14.4 16.6 29.0 39.4 12.3 3.8 26.5 51.4 5.6 54.7 39.6 14.3 8.7 30.1 1.1 0.0 5.1 0.0 11.2 28.5 0.1 1.6 9.5 1.5 8.2 0.0 0.0 5.5 2.3 8.0 7.8 0.8 6.1 0.0 1.5 28.1 2.0 117.6 0.1 0.0 4.2 153.7 532.0 30.9 0.1 5.4 0.1 10.1 3.0 152.7 0.5 22.1 20.4 0.2 70.6 88.4 4.9 0.0 2.3 26.6 37.2 0.1 1.6 29.5 0.3 6.7 0.2 1.2 4.0 2.6 3.5 61.2 0.5 7.6 1.2 9.3 7.2 3.6 0.1 57.3 35.1 158.2 10.1 57.2 16.4 71.3 13.8 18.9 16.0 6.2 15.4 11.3 19.1 5.4 13.7 12.3 9.1 12.4 16.1 6.0 21.5 15.3 23.4 24.4 25.0 19.5 25.2 26.9 26.8 29.2 27.8 29.0 26.5 30.1 18.1 6.4 8.9 57.1 22.4 1.1 0.9 0.8 1.2 0.8 16.1 10.8 60.0 0.0 2.4 1.8 0.0 0.3 23.6 0.1 1.9 0.6 12.0 0.9 2.4 13.2 0.0 11.3 20.6 1.8 0.4 10.7 5.6 1.6 193.9 128.2 12.5 2.5 15.2 13.5 21.6 0.4 0.0 46.5 25.1 35.8 14.9 40.3 3.6 77.8 36.1 4.7 36.0 48.2 4.3 0.7 0.0 14.7 12.8 0.4 0.0 0.2 2.2 0.3 13.1 33.5 18.5 0.7 0.7 0.6 1.7 0.4 40.5 30.1 0.1 0.7 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARL14 "ARF7, FLJ22595" ENSG00000179674 "ADP ribosylation factor like GTPase 14" Q8N4G2 3 160677160-160678448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 129.2;intestine: 51.2;stomach 1: 77.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 588.3;Gastric mucus-secreting cells: 377.7;Intestinal goblet cells: 154.6;Paneth cells: 519.2;Proximal enterocytes: 174.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 6.6;pancreatic cancer: 26.0;stomach cancer: 14.3;urothelial cancer: 8.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "memory B-cell: 1.8" "Lineage enriched" "Detected in single" 18 "B-cells: 1.8" "Cell line enhanced" "Detected in some" "A-431: 9.7;CAPAN-2: 36.2;HaCaT: 9.0;OE19: 25.3;RT4: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.65e-1)" "unprognostic (7.26e-3)" "unprognostic (2.64e-2)" "unprognostic (3.70e-3)" "unprognostic (6.36e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.30e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (4.74e-2)" "unprognostic (4.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-2)" 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 51.2 0.1 0.0 1.0 0.1 129.2 0.0 0.0 0.0 0.4 1.4 0.0 0.2 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.1 36.0 0.0 0.1 0.0 0.0 0.2 34.2 2.8 0.0 0.1 77.2 0.0 0.0 0.3 0.6 0.0 3.2 23.8 0.3 0.0 9.7 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 36.2 0.0 0.8 0.0 4.2 9.0 0.0 0.9 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 25.3 2.0 0.0 0.0 0.3 2.9 17.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.0 1.9 4.5 2.6 0.0 0.0 0.2 0.1 0.0 18.6 1.2 0.0 0.0 0.0 0.0 588.3 0.0 12.6 0.0 5.6 0.4 0.1 89.1 0.0 0.0 41.4 0.1 0.5 377.7 10.7 8.9 0.0 0.0 0.0 0.0 0.0 0.0 154.6 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.3 519.2 0.0 1.0 1.2 174.5 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.9 0.0 1.4 0.0 112.0 25.9 ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 441.6;Inhibitory neurons: 285.2;Microglial cells: 408.5;Oligodendrocyte precursor cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" 14.0 12.5 6.6 5.6 7.5 1.9 13.0 5.6 10.0 17.7 7.2 10.6 11.9 16.0 7.6 9.8 8.2 14.5 14.0 8.5 7.1 17.9 9.8 7.6 6.3 5.8 6.2 5.7 5.0 3.2 8.5 22.3 6.0 10.0 10.9 7.6 10.5 6.8 3.3 11.3 9.9 16.6 6.1 8.2 8.3 9.3 6.8 10.6 8.4 11.7 8.0 13.6 8.8 6.2 3.2 5.5 8.5 15.6 7.0 7.8 11.8 10.2 15.1 9.4 20.7 21.1 8.0 32.0 14.9 9.1 11.0 7.7 13.2 14.1 12.4 3.2 13.9 36.9 7.1 2.8 2.5 4.5 43.8 10.0 10.1 15.8 9.5 14.2 20.8 7.0 32.4 5.3 6.5 7.7 7.5 4.3 3.0 1.6 3.9 6.2 10.4 0.8 12.8 30.3 11.3 7.1 13.1 6.7 7.9 15.6 8.6 4.7 11.4 5.7 9.6 5.4 6.7 1.8 1.7 34.8 9.9 10.6 9.5 1.1 1.8 2.2 1.3 1.4 0.7 1.0 0.9 0.9 2.4 0.7 0.9 0.7 3.5 0.7 1.2 0.3 2.3 1.2 6.6 7.5 5.6 10.0 8.5 7.1 5.8 6.2 6.0 6.1 6.8 6.2 44.5 3.2 7.7 33.6 6.5 9.7 7.9 5.8 8.0 5.1 4.8 5.8 7.5 5.7 4.5 12.9 14.6 52.5 5.2 7.5 21.5 3.2 3.4 4.1 6.9 35.1 20.9 8.6 441.6 4.9 4.9 8.5 6.6 5.1 2.5 3.2 26.0 4.9 8.4 1.7 285.2 7.6 18.3 8.7 8.7 1.5 4.4 12.5 1.8 408.5 5.0 3.2 6.2 184.5 104.7 6.9 7.6 3.8 4.7 5.4 5.7 10.0 3.9 3.0 6.6 3.6 5.3 1.0 3.5 5.9 10.1 42.7 8.9 24.4 7.1 8.4 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.1;Fibroblasts: 10.8;Melanocytes: 21.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 15.7;HaCaT: 31.4;Hep G2: 19.9;hTEC/SVTERT24-B: 30.9;U-87 MG: 39.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" 1.2 0.3 1.6 2.3 2.6 0.6 0.4 2.5 2.1 2.7 0.7 1.6 0.6 3.1 0.6 1.8 2.1 1.1 1.3 1.4 1.8 0.7 0.4 4.5 0.3 3.6 2.4 0.4 0.4 0.6 1.0 2.8 3.9 1.7 0.4 0.4 0.5 0.8 0.8 4.8 0.7 2.8 2.6 0.8 0.8 0.4 2.8 0.3 0.2 0.5 0.4 3.8 2.7 5.5 1.0 3.8 1.1 0.0 0.0 0.8 0.0 8.1 12.1 15.7 11.5 1.1 1.8 0.0 3.1 11.5 1.3 31.4 0.2 5.3 5.6 0.0 0.1 0.0 0.4 19.9 1.5 0.0 0.0 0.8 3.4 30.9 0.9 10.7 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.2 0.0 6.7 0.9 1.3 11.2 0.0 0.0 0.0 0.3 10.2 0.3 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 2.5 2.1 1.4 1.8 3.6 2.4 3.9 2.6 2.8 5.5 0.1 0.0 0.0 0.3 0.0 12.1 0.0 2.4 0.0 0.1 0.1 0.4 1.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 1.1 10.8 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.1 0.0 0.8 0.2 0.6 0.0 21.4 0.0 0.0 3.9 0.0 0.0 2.5 0.4 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.3 0.0 1.8 6.6 0.1 0.9 0.9 4.7 1.4 1.1 0.0 0.0 0.0 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 217.2;tongue: 67.0" "Cell type enhanced" "Detected in some" "Early spermatids: 52.7;Late spermatids: 293.6;Skeletal myocytes: 79.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;prostate cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 1184.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028870: AB_10611679" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.90e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" "unprognostic (6.80e-3)" 0.1 0.0 0.4 0.9 0.5 0.0 0.0 1.3 1.0 1.0 0.2 11.1 0.3 0.6 0.1 10.5 0.1 1.2 3.9 0.5 0.4 0.7 0.0 0.2 0.0 0.9 1.5 0.0 0.0 0.1 0.4 0.0 0.8 12.9 3.3 0.0 23.9 0.3 217.2 0.2 1.2 2.5 0.8 0.0 4.7 7.3 0.5 0.1 0.0 67.0 0.0 19.2 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 29.1 0.0 25.9 54.7 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1184.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.3 1.0 0.5 0.4 0.9 1.5 0.8 0.8 0.5 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.7 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 293.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.8 0.0 0.0 1.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 79.6 0.6 0.9 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1042.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "BEWO: 25.1;NB-4: 8.1;OE19: 14.2;SCLC-21H: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" 0.3 0.2 1.0 1.2 0.6 0.8 0.7 0.5 0.9 2.4 0.4 3.9 6.9 2.2 0.5 1.6 0.4 0.1 0.1 0.9 0.5 1.7 0.8 0.6 0.7 1.7 2.0 0.1 0.7 0.1 0.1 5.5 1.0 2.3 2.5 0.0 8.0 1.6 0.2 7.3 5.5 0.1 1.1 2.3 2.1 0.8 1.4 0.5 0.5 0.0 0.6 1.5 1.9 2.3 0.0 0.0 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.7 0.0 8.1 0.6 14.2 0.0 0.0 0.0 0.0 0.0 0.6 20.5 0.1 0.0 0.5 0.0 0.0 2.5 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.9 1.2 7.9 2.2 1.7 0.1 0.0 0.5 1.3 0.8 0.0 0.1 1.3 0.9 0.0 1.4 0.0 0.0 0.4 1.0 0.6 0.5 0.9 0.9 0.5 1.7 2.0 1.0 1.1 1.4 2.3 1.2 0.0 0.0 0.0 1.4 13.6 14.1 3.3 23.3 0.0 7.2 3.3 0.9 1.5 0.7 20.2 0.0 18.7 29.2 14.4 7.9 0.2 0.1 1.4 4.7 2.6 78.2 4.4 0.0 0.0 1042.9 1.5 10.2 3.5 0.0 0.0 23.2 0.5 31.1 0.0 0.0 31.4 2.0 22.0 7.0 0.2 1.8 14.3 1.8 3.7 22.6 0.0 110.2 0.0 0.0 0.0 3.6 1.5 1.3 6.5 9.1 0.4 1.0 0.1 0.0 0.1 0.3 0.3 13.7 9.1 4.7 23.3 8.9 0.1 112.1 9.4 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.7;Melanocytes: 46.2;Oligodendrocytes: 217.0;Peritubular cells: 48.2;Proximal enterocytes: 37.5;Proximal tubular cells: 74.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 5.4;ASC TERT1: 4.1;CACO-2: 3.8;HSkMC: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 13.9 4.3 25.9 1.8 46.4 1.8 4.1 27.6 40.9 7.5 14.2 4.3 11.2 4.5 6.0 4.9 5.5 3.6 2.7 25.8 27.7 38.2 15.0 3.5 1.5 30.4 35.4 2.9 1.0 0.8 0.8 3.5 29.5 4.1 4.9 2.8 1.8 5.0 11.9 5.2 15.6 3.1 24.7 5.4 4.4 6.6 42.4 0.6 2.1 15.0 0.7 6.3 4.3 69.0 0.2 0.1 0.5 0.5 5.4 4.1 0.3 0.2 0.1 0.2 0.1 3.8 0.2 0.6 0.2 0.7 0.3 0.3 0.3 0.1 0.2 2.0 0.1 0.4 0.7 0.2 0.5 0.4 0.4 7.5 0.3 0.4 0.1 0.1 0.1 0.4 0.3 1.1 0.2 0.2 0.2 0.6 0.4 0.2 0.3 0.3 0.3 0.6 0.2 1.1 0.4 0.3 1.1 0.3 0.9 0.4 0.3 0.2 0.4 0.6 0.4 0.4 0.3 0.7 0.4 0.4 0.2 0.4 0.5 1.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.7 0.3 0.1 0.2 0.1 0.0 25.9 46.4 27.6 40.9 25.8 27.7 30.4 35.4 29.5 24.7 42.4 69.0 5.1 9.6 1.5 12.1 0.1 5.2 1.5 1.6 6.2 5.5 2.1 0.8 1.3 2.8 1.0 25.8 0.0 0.0 0.0 0.3 7.9 0.2 5.0 0.1 4.1 1.1 2.4 2.7 0.6 0.2 0.1 15.0 2.0 0.2 0.0 0.1 3.9 11.5 0.2 8.4 0.4 0.8 2.0 0.8 1.5 2.5 49.7 0.8 46.2 3.7 0.0 4.1 0.0 1.5 217.0 0.0 2.5 48.2 0.2 0.4 37.5 74.8 0.1 0.5 0.0 8.5 11.6 11.1 0.6 0.7 1.7 0.1 0.4 28.3 1.8 2.7 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1284.8;liver: 2037.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 398.7;Hepatocytes: 1062.0;Proximal enterocytes: 618.2;Proximal tubular cells: 1408.9;Urothelial cells: 413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "BJ hTERT+: 893.9;HaCaT: 850.4;hTCEpi: 817.8;RPMI-8226: 1444.5;THP-1: 1061.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 215.0 146.8 29.6 51.3 29.7 0.2 168.2 25.0 31.0 67.0 61.7 157.2 124.5 111.3 124.8 51.1 166.3 110.2 66.5 31.5 38.3 1284.8 2037.7 52.9 7.5 40.2 42.2 57.2 68.4 11.4 45.0 50.6 51.7 56.2 167.9 6.9 119.4 132.6 74.4 131.3 194.8 61.2 28.4 20.0 53.2 35.9 38.4 7.8 92.3 71.4 15.6 288.7 66.6 25.3 124.5 11.9 13.7 23.1 88.4 223.1 43.6 146.2 893.9 28.2 85.5 52.5 34.0 0.4 95.9 300.2 8.2 850.4 59.9 5.2 19.5 21.7 27.1 0.3 18.3 137.3 305.4 18.3 1.6 148.2 817.8 45.4 81.2 0.3 1.1 384.0 5.3 530.6 28.8 619.8 7.2 262.7 19.2 635.9 26.7 1.7 15.4 1444.5 78.8 61.3 342.4 5.8 515.4 534.7 41.5 53.5 366.1 1061.5 0.4 11.3 68.3 2.3 13.0 88.1 91.5 32.1 219.0 137.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 29.6 29.7 25.0 31.0 31.5 38.3 40.2 42.2 51.7 28.4 38.4 25.3 72.1 25.6 28.6 2.6 21.3 70.5 55.7 179.8 53.5 0.1 23.7 17.3 5.4 138.7 104.4 47.8 0.0 178.5 0.4 398.7 133.1 116.5 1.2 4.7 30.5 68.0 12.0 93.7 2.2 110.5 8.9 21.5 20.4 6.2 5.7 55.5 65.7 1062.0 14.7 0.0 8.0 186.8 24.4 40.1 6.5 7.8 31.1 8.0 3.6 7.5 1.6 10.6 0.0 0.0 0.2 70.8 310.4 124.8 11.7 104.0 618.2 1408.9 32.7 0.4 0.0 18.7 13.4 1.4 2.6 23.5 17.5 144.1 11.5 62.0 165.6 413.2 ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 354.6;Excitatory neurons: 370.0;Inhibitory neurons: 1011.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 900.3;Oligodendrocytes: 225.9" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 37.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" 3.3 9.8 26.1 2.7 26.3 3.6 4.3 39.0 36.0 5.3 9.0 5.2 3.4 3.2 3.9 2.2 8.0 2.5 22.5 27.0 25.8 5.5 4.1 2.2 2.4 29.3 36.2 2.8 6.7 3.1 11.6 1.8 28.7 25.2 3.2 13.4 5.8 11.3 7.3 2.4 4.1 2.8 21.4 2.4 5.6 17.6 35.0 6.0 1.8 5.6 1.8 3.2 3.5 39.2 3.7 12.0 4.3 7.1 7.6 7.0 15.4 5.7 2.3 2.5 2.8 8.1 4.4 8.8 6.1 3.8 9.3 1.3 11.5 0.6 3.1 4.8 2.9 3.1 5.8 17.0 3.0 1.8 6.2 9.5 1.1 7.8 0.7 5.4 1.8 10.5 3.9 5.9 7.9 3.8 4.1 1.4 13.2 10.6 6.4 4.9 27.5 2.5 8.0 12.3 6.3 37.9 6.8 2.0 4.8 14.5 15.5 1.3 3.5 5.9 9.1 5.6 4.9 9.0 5.0 8.3 10.5 2.0 25.8 2.5 0.4 0.5 2.8 0.3 3.6 1.5 3.1 2.4 0.2 1.6 3.0 2.5 1.9 5.9 0.6 0.9 8.8 1.0 26.1 26.3 39.0 36.0 27.0 25.8 29.3 36.2 28.7 21.4 35.0 39.2 0.6 6.4 8.9 354.6 1.1 1.3 3.2 0.4 1.2 4.9 4.2 4.8 22.7 2.8 5.0 1.8 10.4 0.4 1.0 0.4 3.9 0.8 122.5 4.7 5.5 1.3 12.6 0.4 370.0 1.1 0.4 4.9 4.1 0.7 6.3 37.0 0.7 2.9 3.2 10.1 1011.0 1.0 0.0 0.0 1.6 228.2 2.8 1.0 0.0 36.5 0.2 3.0 0.0 900.3 225.9 0.5 2.1 5.7 3.6 11.7 5.7 6.9 11.7 5.1 0.0 1.9 2.0 7.7 13.2 0.3 0.6 0.3 3.8 1.9 1.8 2.2 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 215.0;Cone photoreceptor cells: 235.6;Glandular and luminal cells: 176.3;Oligodendrocytes: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 10.2 10.4 12.3 8.9 22.0 18.2 6.1 18.3 16.8 13.0 5.7 4.4 9.9 10.1 5.8 7.0 8.7 15.0 21.4 9.7 12.5 12.7 10.1 39.5 5.8 25.3 22.2 6.5 12.4 23.1 16.2 10.1 22.9 4.3 3.2 14.9 9.0 3.9 13.1 8.9 8.3 9.1 15.7 8.9 5.3 8.9 21.9 8.2 13.9 17.3 6.1 6.5 5.9 40.2 28.0 14.0 17.5 20.5 8.7 11.7 30.9 13.0 7.6 10.9 8.8 44.5 31.5 14.1 15.5 11.0 14.0 23.2 15.8 10.8 10.5 14.2 14.9 16.3 11.9 23.3 13.6 30.8 25.5 7.9 8.2 13.2 8.0 8.8 29.0 12.6 11.4 2.3 7.7 10.5 14.1 19.4 7.5 31.8 9.9 12.2 7.1 8.1 59.3 6.4 27.8 7.7 12.7 16.3 10.7 22.4 6.2 40.4 19.2 0.0 23.3 14.1 9.9 7.4 15.5 5.9 4.8 28.3 12.2 0.0 1.1 1.7 0.4 1.6 0.3 0.6 0.2 0.2 0.6 1.8 0.3 0.2 3.1 0.0 1.5 0.5 0.0 0.3 12.3 22.0 18.3 16.8 9.7 12.5 25.3 22.2 22.9 15.7 21.9 40.2 25.6 218.0 215.0 22.2 11.3 10.8 3.4 4.9 1.2 42.0 5.2 3.7 42.3 31.5 29.4 16.5 235.6 1.7 7.0 2.4 5.9 32.7 0.9 51.2 24.2 34.2 12.0 3.8 35.0 11.4 32.2 16.5 8.6 176.3 12.0 62.2 27.1 16.5 20.7 13.5 32.5 3.5 14.2 33.6 16.9 1.9 11.1 29.3 10.6 48.7 36.9 11.0 6.2 33.7 138.3 24.3 6.1 4.9 7.7 7.7 10.5 15.7 13.3 44.8 0.0 9.5 12.8 4.0 10.1 6.3 9.7 8.6 8.4 8.7 5.9 3.9 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 515.9;skeletal muscle: 882.2;tongue: 478.0" "Cell type enhanced" "Detected in some" "Astrocytes: 515.8;Cardiomyocytes: 158.7;Microglial cells: 141.5;Muller glia cells: 73.0;Oligodendrocyte precursor cells: 94.0;Sertoli cells: 85.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 51.9;HHSteC: 14.6;RH-30: 16.8;U-87 MG: 10.3" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 170000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 37.4 4.1 401.5 1.5 480.5 0.0 27.4 419.8 412.8 9.3 164.9 55.8 3.6 5.6 12.5 33.5 14.5 8.0 144.6 337.4 398.5 3.9 1.2 6.4 0.3 429.5 478.8 18.9 1.4 0.3 32.3 3.3 375.3 28.5 8.1 58.5 18.2 28.5 882.2 4.7 15.9 7.8 365.0 1.8 15.7 5.8 515.9 0.6 3.5 478.0 0.5 29.9 9.8 327.7 0.0 0.0 51.9 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 4.6 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 401.5 480.5 419.8 412.8 337.4 398.5 429.5 478.8 375.3 365.0 515.9 327.7 1.4 0.0 0.0 515.8 0.1 0.5 1.6 0.0 0.6 1.3 2.5 0.9 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 1.2 11.1 0.0 0.0 5.5 0.0 0.0 4.8 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 1.3 1.4 28.9 0.5 0.0 141.5 0.5 73.0 0.0 94.0 2.5 0.0 0.0 39.5 0.0 0.8 0.0 0.1 0.1 3.9 85.5 54.9 45.8 0.3 0.2 0.2 0.6 0.1 0.1 5.8 0.0 0.6 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: AB_2686169" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favorable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 32.2 32.7 34.0 25.3 36.6 38.6 32.9 31.8 42.8 33.4 76.9 36.5 23.9 30.9 28.0 23.6 37.2 27.2 31.9 40.7 38.6 44.7 28.5 51.4 21.9 37.0 38.9 28.8 22.6 78.0 22.7 32.7 40.3 85.8 35.9 59.4 29.2 25.2 28.1 31.9 26.9 31.0 33.6 19.5 31.5 25.2 48.8 36.2 35.0 21.1 26.2 31.6 18.1 48.6 133.1 51.1 49.9 48.5 136.7 110.0 53.9 141.2 186.8 69.4 87.0 83.5 106.3 47.6 95.6 134.4 96.4 153.6 95.1 77.9 100.8 104.4 34.2 127.2 51.5 39.0 87.2 51.2 148.4 86.8 76.6 73.2 82.2 126.3 74.6 59.3 37.3 84.1 86.7 59.0 50.6 40.9 57.0 71.7 54.8 36.3 49.9 75.6 127.5 87.7 76.7 45.9 121.4 37.8 72.8 70.8 55.7 41.7 102.6 73.3 40.8 95.5 65.8 54.6 71.1 69.9 75.8 38.0 62.6 30.6 8.9 15.9 7.4 7.6 7.0 5.6 7.3 6.6 9.5 3.6 4.9 4.9 4.3 11.5 9.6 8.2 9.3 6.5 34.0 36.6 31.8 42.8 40.7 38.6 37.0 38.9 40.3 33.6 48.8 48.6 30.2 38.5 53.0 162.6 17.4 39.4 34.5 34.8 26.7 25.9 34.4 22.4 30.2 35.8 41.1 46.0 20.9 16.3 15.5 39.0 5.9 35.3 17.5 26.9 34.1 27.8 35.6 23.3 172.5 38.0 27.6 25.9 33.1 55.8 28.5 28.2 26.7 27.4 27.7 82.4 136.5 32.4 36.7 26.2 34.8 18.9 16.1 39.5 21.4 128.4 20.5 26.4 19.6 148.3 154.3 51.1 27.5 14.7 18.5 69.0 16.3 19.8 52.7 33.4 6.6 27.7 25.9 16.2 14.1 24.7 52.8 17.6 19.5 17.3 31.2 36.9 ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1595.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 2375.2;Proximal tubular cells: 1906.2;Syncytiotrophoblasts: 708.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031069 Supported Supported Mitochondria NA NA 820000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA031069: AB_10603676" "unprognostic (3.52e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (1.43e-1)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (4.87e-2)" "unprognostic (1.77e-1)" "unprognostic (8.83e-2)" "prognostic favorable (2.37e-5)" "unprognostic (1.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" 274.6 276.3 291.2 136.4 295.4 175.1 205.5 302.5 424.4 156.3 316.1 333.5 276.4 128.8 368.1 258.1 129.9 129.7 1052.1 295.2 306.2 489.5 756.3 110.8 166.4 299.3 297.8 127.2 188.2 458.8 140.4 171.5 295.7 160.1 314.4 249.5 214.6 228.5 1161.7 113.6 250.6 189.8 298.7 111.2 226.9 131.5 299.4 217.5 166.0 1595.8 210.9 194.9 138.4 299.6 355.9 260.0 314.5 351.4 344.8 313.5 389.4 305.8 373.0 305.8 300.8 607.6 274.4 439.3 194.2 312.9 467.8 191.5 441.3 379.2 339.2 373.1 441.1 910.6 520.6 618.4 386.8 673.2 284.5 303.1 471.2 284.0 258.6 399.9 363.0 412.2 582.2 522.9 458.2 416.3 468.6 683.2 562.3 824.0 460.7 358.0 606.5 840.0 669.8 504.6 360.2 394.1 516.5 521.7 493.0 449.4 376.5 590.5 260.6 219.6 266.6 209.3 265.9 501.7 954.7 568.2 341.5 707.8 283.1 444.8 447.0 443.7 293.3 487.1 316.1 475.1 385.5 368.6 531.9 399.7 377.4 370.7 292.3 389.9 505.7 504.0 520.3 661.3 291.2 295.4 302.5 424.4 295.2 306.2 299.3 297.8 295.7 298.7 299.4 299.6 532.1 169.9 179.3 0.0 56.0 0.0 0.0 0.0 0.0 0.0 346.3 468.4 0.0 0.0 105.9 419.3 0.0 652.7 116.4 0.0 2375.2 447.0 0.0 299.2 257.6 150.6 0.0 0.0 0.0 472.5 522.8 135.6 0.0 308.5 109.7 341.2 0.0 0.0 522.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 154.2 0.0 0.0 226.4 0.0 0.0 0.0 0.0 427.1 0.0 0.0 21.4 0.0 0.0 1906.2 142.1 0.0 0.0 0.0 161.4 0.0 0.0 0.0 0.0 708.2 79.2 387.8 0.0 0.0 ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Uncertain NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" 56.3 93.5 108.3 43.1 109.2 59.1 56.7 99.6 118.0 59.6 123.6 61.5 48.4 54.2 145.1 85.2 60.0 46.0 92.7 116.2 115.4 104.3 51.4 96.8 46.9 114.0 96.8 63.3 86.6 176.0 110.4 77.9 121.6 85.1 57.0 74.0 87.4 54.8 53.8 83.6 57.4 49.0 104.6 94.7 70.4 47.5 104.2 40.9 81.9 54.4 42.5 63.7 60.9 121.6 110.1 101.6 88.2 146.2 145.7 77.4 162.2 78.5 116.6 122.5 176.1 93.4 135.1 64.7 337.8 177.1 216.5 112.3 133.8 71.9 76.6 58.6 135.1 37.5 113.7 100.0 170.6 60.9 260.2 98.1 126.7 112.4 68.2 139.5 177.0 47.8 45.6 176.4 84.7 158.1 43.6 96.8 32.1 171.0 100.8 66.6 59.1 170.7 139.9 87.3 84.6 89.7 72.6 289.7 159.3 87.3 123.1 157.8 135.5 87.4 79.0 151.1 135.6 256.3 311.8 77.0 104.4 132.8 90.2 246.6 295.1 363.9 147.3 313.8 148.6 91.7 118.4 127.8 376.7 113.6 107.1 117.8 326.9 140.3 255.6 215.9 155.2 216.9 108.3 109.2 99.6 118.0 116.2 115.4 114.0 96.8 121.6 104.6 104.2 121.6 39.4 38.5 57.5 17.0 32.3 30.2 42.7 122.4 25.6 105.8 58.5 42.2 37.7 54.3 102.1 97.5 47.9 145.1 40.1 84.3 19.6 65.4 3.1 52.5 33.7 50.1 89.0 35.8 17.0 52.5 104.5 48.8 36.7 57.4 77.3 51.8 54.3 46.6 246.3 129.5 24.2 59.0 160.7 143.6 88.2 5.5 41.3 130.3 72.9 15.0 79.9 68.4 27.8 22.1 26.4 42.4 67.5 42.5 61.7 34.1 63.7 49.1 112.5 69.2 65.7 35.7 45.5 64.4 10.7 31.6 32.8 196.5 36.3 74.1 54.6 47.2 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587706-114598915 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli NA NA 96000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoli Nucleoplasm "CAB004615: AB_2258908, HPA042898: AB_2678217" "unprognostic (3.85e-1)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.84e-3)" "unprognostic (2.49e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (3.47e-3)" "unprognostic (9.40e-3)" "unprognostic (4.13e-2)" "prognostic favorable (1.73e-7)" "unprognostic (2.44e-2)" "unprognostic (1.50e-1)" "unprognostic (9.11e-2)" "unprognostic (3.92e-2)" 79.5 140.2 70.5 80.5 71.1 131.4 108.4 74.0 101.1 85.0 85.0 70.5 59.4 92.4 177.3 132.5 71.3 64.6 93.0 72.1 79.4 138.1 125.9 84.9 115.4 75.4 79.1 106.2 72.5 172.9 135.1 91.2 80.2 132.7 65.5 91.2 111.9 55.1 124.0 98.1 69.2 60.6 71.5 93.9 121.1 75.4 75.6 104.2 99.2 113.0 100.8 106.8 94.0 75.4 83.6 71.0 153.2 38.8 111.0 84.5 148.3 125.2 86.6 88.5 63.4 92.3 94.8 74.2 106.8 80.0 183.2 179.0 105.6 84.6 79.3 63.2 73.8 72.3 84.4 143.4 156.8 173.1 135.1 105.2 227.9 72.7 87.3 104.1 91.0 123.1 136.0 164.4 131.6 159.0 164.6 113.6 187.0 222.2 126.8 159.0 95.0 126.7 195.2 128.4 113.8 156.3 159.7 284.0 487.6 143.9 235.0 202.5 118.9 80.1 68.9 132.3 142.0 213.6 474.5 139.6 106.8 97.2 112.0 490.1 327.8 495.0 212.6 331.2 264.9 549.6 288.8 255.8 255.0 501.7 374.7 305.5 405.4 255.4 348.4 401.5 398.9 756.7 70.5 71.1 74.0 101.1 72.1 79.4 75.4 79.1 80.2 71.5 75.6 75.4 230.6 160.3 176.6 19.6 353.9 519.0 492.9 1068.9 277.7 170.5 470.4 494.1 151.6 163.0 629.7 331.1 41.7 346.1 268.2 198.5 970.5 374.1 85.7 381.6 223.8 227.7 360.7 157.6 35.0 263.6 336.5 247.0 231.4 594.9 267.4 156.8 219.2 337.1 548.1 164.9 37.4 346.8 1133.2 350.1 517.8 60.3 306.0 382.4 494.5 20.6 699.7 360.9 261.6 20.1 22.9 430.5 218.1 250.9 255.0 686.5 176.7 1021.5 426.3 158.6 236.7 155.6 393.0 400.6 326.7 361.4 576.7 757.4 304.0 280.3 201.6 852.2 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 191.7;Inhibitory neurons: 137.0;Oligodendrocytes: 137.5;Proximal tubular cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 17.2 41.9 11.8 6.3 12.3 4.8 15.9 16.0 15.3 13.6 17.9 17.2 23.8 10.2 14.2 8.6 12.4 10.7 38.9 12.1 14.3 62.9 26.4 10.3 7.6 14.8 13.6 13.4 25.5 45.4 10.4 16.1 15.2 28.2 17.2 21.4 26.1 14.8 24.2 8.7 20.1 8.6 12.2 8.0 22.7 5.5 14.1 9.0 21.0 29.2 7.7 9.1 9.8 15.0 9.1 8.7 12.0 6.2 14.5 15.5 18.5 8.0 10.0 6.1 7.0 5.0 11.4 10.6 8.1 8.5 18.2 13.0 18.1 10.1 8.7 82.6 15.4 7.3 9.7 29.6 11.1 10.6 7.3 13.1 12.5 4.9 16.8 14.3 7.6 10.7 10.3 15.5 7.2 8.8 14.6 23.8 15.0 22.2 12.5 8.5 9.6 18.6 26.6 4.8 12.2 8.8 11.9 28.3 15.6 27.1 5.2 6.9 7.8 6.1 7.6 9.0 7.8 17.7 16.1 3.6 9.6 8.5 4.2 17.9 5.2 18.2 7.2 3.6 8.1 8.4 7.8 10.4 4.6 11.8 9.6 9.1 7.4 10.8 2.5 6.3 10.8 6.5 11.8 12.3 16.0 15.3 12.1 14.3 14.8 13.6 15.2 12.2 14.1 15.0 9.6 0.0 7.7 75.1 11.2 5.2 24.5 27.7 12.5 18.7 15.8 13.5 37.2 27.1 19.1 27.6 25.0 44.6 11.5 27.0 191.7 29.6 3.1 11.5 11.1 11.1 22.9 28.8 101.2 16.1 28.9 14.2 19.4 16.0 1.3 14.5 11.0 18.3 13.4 13.5 137.0 17.3 38.7 8.9 4.7 1.1 14.3 8.9 12.4 67.5 29.1 9.5 18.6 100.5 137.5 12.5 23.5 11.3 18.4 36.8 59.4 120.0 15.8 34.4 13.1 11.9 11.5 8.7 10.5 16.1 4.1 36.4 12.9 11.6 25.0 24.2 AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 4 "Adipocytes: 48.0;Collecting duct cells: 49.7;Endothelial cells: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;SCLC-21H: 3.7;U-266/84: 3.7;U-698: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" 5.2 0.2 0.1 0.2 0.0 0.8 3.1 3.9 0.1 1.0 0.5 0.8 0.6 0.9 0.1 0.6 1.6 1.0 5.1 0.1 0.0 8.1 0.0 1.3 1.0 0.3 0.5 0.2 0.6 0.7 0.1 0.2 0.4 0.7 0.2 0.0 0.7 0.6 3.1 1.5 0.8 0.8 0.1 0.3 0.7 0.2 0.1 0.4 0.9 4.0 0.3 0.8 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.1 1.2 0.6 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.8 1.0 0.1 0.0 0.0 1.4 0.6 1.4 0.0 0.0 3.7 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.6 3.7 3.6 0.0 0.9 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.1 0.0 0.3 0.5 0.4 0.1 0.1 0.2 48.0 3.2 1.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 49.7 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.6 0.8 0.0 0.0 0.1 1.3 0.0 0.1 0.5 0.0 0.1 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0;salivary gland: 31.4;stomach 1: 43.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 65.8;Cytotrophoblasts: 78.9;Distal enterocytes: 108.4;Paneth cells: 67.4;Proximal enterocytes: 50.5;Syncytiotrophoblasts: 68.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 44.2;BEWO: 40.9;CAPAN-2: 112.5;OE19: 102.1;RT4: 41.3;SK-BR-3: 38.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" NA NA 74000 "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" 0.3 0.1 0.3 5.7 0.1 0.2 3.4 0.7 0.4 4.4 0.3 44.0 32.6 0.4 0.0 21.7 1.0 23.8 0.0 0.3 0.3 3.8 2.4 0.5 0.5 0.3 0.2 0.1 3.9 0.5 0.0 12.6 0.3 2.2 40.5 0.0 31.4 3.2 0.0 2.7 29.5 1.7 0.0 0.1 43.2 0.1 0.1 0.2 0.3 0.0 4.7 18.5 8.1 0.5 44.2 12.5 0.0 0.2 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.7 112.5 0.0 28.9 0.0 0.1 4.2 0.0 12.9 0.0 0.0 0.2 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.2 0.1 0.4 102.1 19.2 0.2 0.0 1.2 23.9 41.3 0.0 0.1 0.0 38.4 0.0 0.0 1.7 0.2 0.1 0.3 3.3 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.4 0.3 0.3 0.3 0.2 0.3 0.0 0.1 0.5 0.1 0.0 2.3 0.0 0.2 0.1 3.6 5.1 0.0 0.0 7.1 6.2 0.4 65.8 17.1 16.5 0.0 78.9 0.5 108.4 1.9 17.9 0.0 3.8 0.8 2.3 16.3 0.0 0.1 28.4 7.5 0.7 19.9 7.7 5.7 0.0 0.7 0.2 6.0 0.0 0.2 40.7 6.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 33.2 67.4 0.0 0.0 7.8 50.5 3.5 7.7 0.0 0.0 0.0 0.9 0.2 0.3 0.2 0.0 68.3 0.2 0.5 28.4 39.6 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 BAG2 ENSG00000112208 "BAG cochaperone 2" O95816 6 57172326-57189833 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.3;Early spermatids: 152.3;Spermatocytes: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018862, HPA019918" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Intermediate filaments" "HPA018862: AB_2669957, HPA019918: AB_2670317" "unprognostic (3.93e-1)" "unprognostic (1.62e-1)" "unprognostic (2.60e-1)" "unprognostic (1.33e-1)" "unprognostic (5.63e-2)" "unprognostic (8.32e-3)" "prognostic unfavorable (6.72e-6)" "unprognostic (1.10e-1)" "unprognostic (7.79e-5)" "unprognostic (6.20e-3)" "unprognostic (4.71e-2)" "unprognostic (6.56e-2)" "unprognostic (6.07e-3)" "unprognostic (5.97e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.26e-4)" "unprognostic (6.24e-3)" 3.7 4.4 2.5 6.6 2.7 1.5 1.7 2.8 4.0 11.4 3.0 32.6 2.1 25.1 3.9 7.2 9.1 7.3 9.1 2.5 2.7 2.8 4.1 5.0 2.7 2.3 2.7 8.5 1.6 0.4 2.0 7.6 2.4 11.2 4.5 4.9 1.0 15.9 9.2 1.3 6.5 29.0 2.3 1.1 7.8 6.4 2.6 1.3 4.6 6.5 2.1 22.5 5.9 3.0 17.2 9.3 3.9 13.8 9.4 26.9 10.9 27.2 25.8 19.2 18.2 12.1 8.6 5.7 25.3 43.2 15.7 3.1 22.5 2.4 18.3 18.3 16.4 16.7 13.3 27.5 14.5 14.8 3.7 13.1 1.2 15.8 14.6 11.4 15.2 13.0 34.1 7.9 19.1 1.3 10.5 12.4 14.8 0.3 9.6 9.5 10.9 11.4 23.2 2.8 4.9 4.4 12.2 0.9 10.1 17.8 2.1 12.7 20.8 10.9 17.9 23.2 27.4 5.3 5.5 12.5 9.7 5.8 1.0 0.1 0.2 0.5 1.9 0.2 2.2 3.5 1.7 1.9 0.9 3.0 3.4 2.9 0.1 2.1 0.0 0.3 2.0 1.1 2.5 2.7 2.8 4.0 2.5 2.7 2.3 2.7 2.4 2.3 2.6 3.0 2.4 3.2 3.7 4.6 16.7 2.4 4.6 5.0 1.8 6.9 4.1 2.7 40.0 0.0 3.8 3.7 12.5 73.3 8.0 0.6 1.9 11.6 152.3 11.0 35.5 3.1 1.8 12.2 8.1 3.7 18.2 46.2 3.1 4.2 4.5 25.6 2.2 15.8 15.8 10.1 10.0 0.3 14.2 2.6 6.6 35.9 31.1 5.1 7.2 5.6 9.1 8.2 3.1 10.6 10.6 5.4 1.3 38.7 13.0 6.2 0.4 33.9 9.1 16.9 6.6 32.1 31.0 93.5 9.8 1.3 3.8 18.9 12.2 30.6 1.3 2.1 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BAIAP2L1 IRTKS ENSG00000006453 "BAR/IMD domain containing adaptor protein 2 like 1" Q9UHR4 7 98291650-98401090 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 58.8" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 108.1;Prostatic glandular cells: 114.7;Urothelial cells: 147.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 72.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "HPA019484: AB_1845265, HPA021257: AB_1845266, HPA023874: AB_1845267, HPA029503: AB_10602330" "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.00e-1)" "unprognostic (2.95e-1)" "unprognostic (2.80e-2)" "unprognostic (8.31e-3)" "unprognostic (4.56e-2)" "unprognostic (1.34e-2)" "unprognostic (9.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" 5.8 20.7 1.5 6.2 1.5 0.4 7.8 1.3 1.7 10.1 3.1 23.0 28.6 2.8 1.4 29.2 11.6 15.5 5.2 1.4 2.1 13.9 33.4 14.0 1.4 1.7 1.7 1.3 31.2 13.1 13.0 10.2 1.8 26.2 21.4 0.6 23.6 2.6 2.8 19.9 25.4 2.6 1.5 1.9 58.8 9.8 1.8 2.1 14.9 1.6 4.6 16.8 17.1 1.8 43.2 33.6 0.9 0.7 0.0 1.5 55.0 10.9 7.1 5.6 4.1 47.0 62.9 1.8 15.9 4.1 47.4 37.3 15.6 46.1 5.0 0.2 20.3 0.0 14.3 27.0 6.7 0.0 14.7 1.5 61.0 3.2 44.4 12.3 0.2 0.1 26.4 0.1 4.8 36.1 0.1 0.1 26.3 61.8 18.5 0.1 0.5 7.0 35.2 37.2 23.5 4.6 25.3 72.2 12.8 35.3 20.2 1.0 1.4 8.3 39.6 1.6 5.1 0.9 13.1 21.8 0.9 5.4 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.5 1.3 1.7 1.4 2.1 1.7 1.7 1.8 1.5 1.8 1.8 16.9 12.8 22.9 23.5 0.8 16.7 64.8 31.5 14.2 0.6 17.4 7.6 2.3 30.0 36.3 22.0 4.2 11.8 5.5 100.3 9.8 60.8 33.1 25.2 3.0 11.2 32.2 2.7 23.1 77.6 78.4 2.2 108.1 33.4 0.0 4.5 0.7 16.6 2.4 1.7 26.1 53.6 18.3 0.3 1.7 52.5 0.9 1.0 8.8 37.5 2.6 1.2 0.0 26.7 31.4 102.6 84.7 0.7 0.6 114.7 35.3 2.4 58.6 0.8 0.0 1.9 6.7 50.0 56.3 22.4 19.5 12.2 1.9 0.2 44.7 147.8 BASP1 "CAP-23, CAP23, NAP-22, NAP22" ENSG00000176788 "Brain abundant membrane attached signal protein 1" P80723 5 17065598-17276843 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 486.3;epididymis: 303.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 345.6;Extravillous trophoblasts: 362.9;Langerhans cells: 489.4;Muller glia cells: 796.9;Syncytiotrophoblasts: 738.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 128.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 128.5" "Cell line enhanced" "Detected in many" "GAMG: 467.0;HeLa: 800.8;SiHa: 830.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045218, HPA050333" Enhanced Enhanced "Plasma membrane" NA NA 63000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA045218: AB_2679263, HPA050333: AB_2681090" "unprognostic (3.35e-2)" "unprognostic (3.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.25e-11)" "unprognostic (1.95e-3)" "unprognostic (1.04e-1)" "unprognostic (3.61e-2)" "unprognostic (1.70e-1)" 35.3 13.8 235.9 73.6 257.0 87.6 14.0 103.0 486.3 56.9 79.9 12.5 7.3 37.3 303.3 10.9 11.4 29.2 13.9 247.3 210.9 15.1 17.2 36.5 80.9 134.7 153.1 36.6 3.7 3.4 21.2 92.1 184.3 79.7 10.8 74.3 13.2 21.6 2.3 22.0 22.2 33.4 107.7 76.5 22.7 2.9 157.1 24.1 11.3 6.8 91.5 57.9 27.3 281.8 0.1 125.6 152.7 0.2 71.7 76.1 227.1 161.7 50.9 127.9 135.0 6.1 0.1 51.3 22.4 112.0 467.0 10.6 98.2 109.2 164.8 21.3 57.9 0.4 800.8 0.3 158.9 101.3 1.4 131.2 132.7 145.6 121.0 163.9 140.1 0.2 0.4 0.5 138.2 183.7 0.3 92.5 115.7 0.3 39.6 0.1 0.5 28.0 46.5 31.3 99.3 21.3 830.7 72.3 0.2 336.5 0.3 101.9 187.7 169.3 0.6 14.2 26.1 1.7 0.2 27.1 171.2 123.0 23.1 25.0 3.1 25.3 0.0 1.5 0.0 5.4 0.0 0.0 4.9 7.9 0.0 0.0 128.5 1.8 2.1 0.5 0.3 0.8 235.9 257.0 103.0 486.3 247.3 210.9 134.7 153.1 184.3 107.7 157.1 281.8 8.0 9.6 4.8 22.2 158.7 215.9 88.0 21.3 58.1 54.8 9.8 10.2 1.6 0.0 15.8 9.2 12.5 155.0 3.8 0.6 0.0 0.6 0.9 98.4 345.6 30.2 0.0 18.1 254.0 3.4 362.9 102.6 23.4 156.4 27.3 18.1 35.7 2.5 53.8 244.0 125.3 0.7 12.2 227.9 489.4 0.0 0.6 298.5 28.4 53.4 275.1 796.9 1.0 115.1 23.7 1.0 0.2 0.0 173.0 121.0 0.0 0.3 93.5 58.4 0.0 2.0 66.2 0.4 3.4 21.0 58.8 738.5 11.9 8.3 1.8 13.2 BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.7;lymphoid tissue: 30.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 105.4;Breast myoepithelial cells: 73.9;granulocytes: 243.7;NK-cells: 103.0;T-cells: 116.5;Urothelial cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.3" "Cell line enhanced" "Detected in many" "HDLM-2: 368.9;MCF7: 134.7;RT4: 83.3;SK-BR-3: 64.8;U-937: 101.6" "Not detected" "Not detected" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA059588: AB_2684074, HPA064962: AB_2685392" "unprognostic (3.33e-3)" "unprognostic (4.87e-3)" "prognostic unfavorable (8.30e-4)" "prognostic favorable (5.35e-6)" "unprognostic (3.02e-2)" "prognostic favorable (7.91e-5)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (6.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (3.74e-9)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "prognostic favorable (4.30e-4)" 5.5 1.3 1.0 20.5 1.8 21.7 7.8 1.0 1.4 2.2 1.1 3.0 2.6 1.3 1.1 2.9 1.9 5.8 2.4 1.0 1.2 1.4 2.9 8.0 30.6 1.5 1.4 0.5 0.9 8.0 0.5 4.1 1.7 5.5 1.4 0.0 6.5 1.8 0.4 2.9 9.7 2.3 1.2 26.9 7.8 0.6 2.2 7.2 1.9 1.0 20.4 18.2 2.9 1.5 4.7 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 368.9 0.0 7.5 0.0 1.6 11.5 10.0 36.3 0.1 0.0 0.0 0.0 0.0 0.0 8.1 2.0 10.3 0.0 134.7 4.7 30.8 0.2 54.9 0.0 1.1 0.0 6.3 0.0 83.3 0.1 0.0 0.0 64.8 2.7 0.0 6.1 18.7 0.0 0.0 0.0 4.4 0.3 32.8 36.9 0.3 0.0 101.6 0.1 3.6 25.5 8.2 55.0 13.7 43.4 21.3 59.7 74.2 25.2 17.5 23.1 50.4 14.4 21.3 13.2 2.9 130.3 27.8 1.0 1.8 1.0 1.4 1.0 1.2 1.5 1.4 1.7 1.2 2.2 1.5 2.9 9.6 29.3 0.0 17.1 5.4 50.8 5.7 0.6 0.0 105.4 73.9 0.3 1.5 13.5 3.7 0.0 0.4 36.9 0.0 0.0 0.8 0.5 0.9 0.6 5.0 0.0 7.2 0.2 2.5 0.4 4.4 10.2 1.9 243.7 0.0 2.5 0.7 61.3 0.0 0.1 0.0 34.6 15.4 10.7 0.6 0.0 21.7 5.4 1.0 16.7 0.0 103.0 0.0 0.1 11.0 0.1 0.0 29.9 22.1 0.0 0.2 12.8 0.0 0.0 1.0 2.0 0.0 0.1 0.4 3.4 1.1 116.5 0.2 0.5 74.3 BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in many" "Adipocytes: 374.9;Basal respiratory cells: 454.1;Collecting duct cells: 548.1;Cytotrophoblasts: 705.4;Syncytiotrophoblasts: 433.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 493.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 142.7;HaCaT: 298.4;SK-BR-3: 276.8;T-47d: 157.2;U-2 OS: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 18000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli fibrillar center" "HPA005654: AB_2667378" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (2.61e-3)" "unprognostic (1.41e-1)" "prognostic favorable (5.94e-6)" "unprognostic (1.83e-2)" "unprognostic (5.74e-2)" "unprognostic (2.14e-2)" "unprognostic (9.97e-3)" 105.0 23.3 24.0 9.9 23.3 3.8 125.6 23.7 39.6 87.7 38.2 32.2 13.5 78.1 21.3 29.1 115.1 15.8 118.3 21.3 24.6 316.8 38.4 89.0 9.8 26.7 27.4 50.2 51.5 20.0 38.3 44.1 26.7 130.1 5.3 3.1 65.6 49.2 44.7 54.1 31.2 19.6 24.0 36.4 39.3 20.6 28.2 13.8 215.7 30.8 7.1 52.8 72.0 21.6 34.7 44.3 1.2 120.8 0.6 0.8 142.7 13.3 6.3 10.7 7.1 66.8 83.5 0.0 65.7 1.6 0.6 298.4 10.4 74.5 3.2 0.1 7.3 0.2 8.8 93.9 23.6 0.0 15.9 11.6 28.6 3.7 4.4 34.2 6.6 0.0 7.3 0.5 1.6 17.7 0.4 1.2 13.5 10.0 15.1 0.5 14.2 3.6 90.4 21.9 0.4 0.5 54.0 276.8 3.4 13.1 157.2 5.1 17.4 2.7 130.2 3.4 6.5 0.6 1.4 0.1 1.1 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 23.3 23.7 39.6 21.3 24.6 26.7 27.4 26.7 24.0 28.2 21.6 374.9 6.4 12.3 5.5 4.4 40.7 118.0 454.1 80.2 2.5 109.5 185.4 12.8 52.9 48.5 548.1 0.0 705.4 3.2 8.6 82.2 34.0 1.3 62.9 8.2 214.0 52.0 4.8 0.5 4.0 36.9 21.7 15.8 45.3 0.0 14.3 73.2 31.0 44.7 0.0 1.2 5.6 40.7 8.0 21.3 2.1 29.5 3.5 16.0 9.4 0.1 23.6 0.0 1.0 0.3 14.3 21.4 15.1 2.5 80.4 4.9 149.6 20.7 1.1 157.8 14.1 240.6 3.2 18.3 8.9 24.6 433.3 3.5 6.4 13.0 40.7 BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 890.2;choroid plexus: 301.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 182.6;Gastric mucus-secreting cells: 202.9;Intestinal goblet cells: 371.4;Oligodendrocyte precursor cells: 538.8;Oligodendrocytes: 718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "MCF7: 44.2;OE19: 90.0;RT4: 179.5;SK-BR-3: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB033558: AB_2274632, HPA051816: AB_2681623, HPA054745: AB_2682590" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (7.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-1)" "unprognostic (3.80e-1)" "unprognostic (1.19e-1)" "unprognostic (5.25e-2)" "unprognostic (2.91e-2)" "unprognostic (4.70e-3)" "unprognostic (3.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (7.77e-3)" 1.2 0.2 506.5 6.4 627.9 0.1 3.4 551.3 890.2 7.3 301.2 69.5 19.0 1.3 2.2 7.2 1.5 8.6 0.4 421.4 525.8 3.3 0.4 2.9 0.6 749.3 660.7 0.4 0.9 0.0 1.0 0.1 649.9 33.4 74.3 0.2 22.3 0.3 0.5 1.4 31.1 2.8 584.8 0.5 159.8 3.4 562.0 0.7 0.3 0.8 6.5 35.7 7.5 724.7 0.0 8.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.7 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 27.8 0.2 0.0 0.3 4.0 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 44.2 0.1 0.2 0.2 90.0 0.0 2.3 0.0 1.2 0.0 179.5 0.2 0.1 0.0 368.6 0.4 0.0 12.2 0.0 0.0 0.0 0.1 3.2 0.0 0.9 0.5 1.0 0.9 0.0 0.3 0.3 0.1 0.0 0.2 0.0 1.2 0.6 0.4 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.1 0.1 506.5 627.9 551.3 890.2 421.4 525.8 749.3 660.7 649.9 584.8 562.0 724.7 0.8 9.6 1.1 1.6 2.8 0.8 6.3 8.5 0.6 0.1 6.2 1.9 2.2 7.2 35.9 3.7 0.0 0.2 0.4 182.6 1.9 2.9 15.6 9.4 11.1 0.4 8.4 0.0 1.6 22.5 0.1 0.8 202.9 11.8 4.5 0.0 0.4 0.1 0.1 0.0 2.5 371.4 18.3 0.0 2.5 16.1 0.3 1.7 16.0 0.0 0.0 0.8 0.0 538.8 718.8 22.9 102.0 0.0 1.0 21.3 12.0 0.1 100.5 0.5 0.0 1.4 2.2 15.4 6.1 0.3 0.3 0.0 1.7 0.4 35.6 56.7 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 525.1" "Group enriched" "Detected in many" 9 "Hepatocytes: 420.3;Oligodendrocyte precursor cells: 210.1" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Karpas-707: 785.6" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 9400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 30.4 11.6 9.3 2.7 7.4 0.0 4.7 7.5 12.0 22.0 5.0 36.1 4.7 41.0 24.3 25.8 36.2 6.0 9.7 7.9 7.3 4.9 525.1 10.9 0.2 7.9 9.4 3.7 2.3 0.1 1.8 0.0 7.8 12.5 16.1 8.8 1.9 32.3 2.7 8.7 10.6 29.7 7.4 5.9 3.5 1.3 12.2 2.9 1.3 5.1 0.1 11.3 5.1 9.4 0.0 2.1 82.1 0.1 0.2 0.0 0.1 0.0 1.5 0.6 7.3 0.0 0.1 0.3 30.7 0.0 0.0 0.5 5.7 0.4 5.8 0.4 0.8 0.0 0.0 0.0 6.3 0.2 0.4 23.5 1.4 0.0 8.1 25.3 3.6 30.0 0.0 785.6 0.0 0.0 0.0 0.1 2.1 0.0 0.8 0.0 28.4 67.3 0.7 0.0 0.0 0.8 0.1 0.0 46.5 0.0 34.0 0.2 0.0 19.3 0.5 0.0 8.3 3.5 0.0 1.6 8.2 0.2 84.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 7.4 7.5 12.0 7.9 7.3 7.9 9.4 7.8 7.4 12.2 9.4 5.8 0.0 0.0 1.0 0.7 5.5 0.9 0.0 1.8 1.4 0.0 0.1 9.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.7 3.4 0.0 8.0 3.0 0.0 0.0 22.0 0.5 0.0 0.0 0.2 8.9 420.3 0.1 1.7 10.5 0.4 0.0 4.7 1.5 8.7 2.1 0.3 19.6 3.7 0.0 31.7 0.0 210.1 16.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 1.2 0.0 0.8 6.5 0.3 0.3 0.6 3.4 0.0 1.1 0.1 0.0 0.1 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" 48.5 36.6 102.4 26.0 95.3 13.9 35.6 83.7 112.4 30.2 61.8 86.9 28.5 43.0 30.5 46.8 35.4 24.7 37.3 89.8 88.8 35.0 20.9 34.6 13.9 94.8 94.0 31.8 53.3 52.9 38.1 23.8 91.7 47.4 31.8 51.9 52.2 45.5 24.2 46.5 34.3 41.5 101.0 20.5 54.2 25.1 108.3 10.7 38.5 19.9 16.4 55.6 34.9 92.4 24.1 23.0 25.6 19.0 43.4 39.2 19.3 43.9 28.5 21.8 24.9 16.3 42.6 16.8 14.2 26.6 27.4 43.9 15.9 28.1 29.4 8.9 12.7 18.4 44.4 30.3 26.6 20.7 30.0 30.3 54.0 17.6 27.1 30.6 18.6 2.9 17.3 18.0 27.8 17.8 1.6 14.5 8.0 33.4 41.3 12.8 28.1 8.2 19.7 45.5 31.7 18.0 20.8 31.3 31.2 15.6 20.6 15.5 37.1 35.1 24.8 27.6 23.1 22.0 12.7 2.2 21.6 16.0 43.5 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 102.4 95.3 83.7 112.4 89.8 88.8 94.8 94.0 91.7 101.0 108.3 92.4 9.2 9.6 13.1 0.0 2.6 8.7 9.5 12.7 5.7 20.0 11.0 8.0 28.9 4.3 13.6 5.5 25.0 5.3 3.5 16.8 13.7 8.0 20.1 11.1 10.4 10.8 18.6 2.1 0.0 18.3 4.0 10.4 9.7 12.1 5.7 12.0 11.4 7.2 5.5 20.2 0.0 16.8 6.1 8.4 4.0 6.1 11.1 5.5 7.2 0.0 7.5 7.4 2.1 0.0 0.0 25.5 11.0 21.4 4.5 17.2 16.3 9.2 12.2 12.7 6.6 12.6 15.5 0.5 0.9 10.8 11.1 5.6 1.5 8.9 10.5 17.6 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BCL7B ENSG00000106635 "BAF chromatin remodeling complex subunit BCL7B" Q9BQE9 7 73536356-73557690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Wnt signaling pathway" "Allergen, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049943, HPA058069" Approved Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA049943: AB_2680963, HPA058069: AB_2683594" "unprognostic (2.79e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (3.54e-3)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" "unprognostic (4.84e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (5.37e-2)" "unprognostic (9.43e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.41e-2)" "unprognostic (1.32e-1)" 35.6 23.8 34.9 18.7 35.0 90.0 18.5 28.1 43.5 16.3 28.3 32.6 21.8 15.5 17.4 27.5 16.6 22.5 49.5 36.5 34.1 21.9 25.1 27.4 24.4 30.6 31.2 9.0 25.6 30.3 20.9 21.7 29.7 17.8 16.4 17.7 16.0 23.5 66.0 11.1 23.6 29.8 28.3 23.0 20.6 20.5 33.4 22.4 22.1 55.8 19.4 33.4 11.4 34.3 67.8 46.9 26.7 47.8 21.5 34.0 27.1 56.1 58.9 58.0 52.9 52.0 73.8 56.7 14.0 58.7 84.7 30.4 19.4 45.7 42.7 73.9 27.5 31.5 28.7 28.0 61.3 54.3 85.3 22.8 45.0 59.5 58.7 23.9 38.4 31.7 50.6 65.0 41.6 79.5 93.0 71.2 46.5 43.0 67.7 49.2 28.6 67.6 46.5 51.8 59.7 57.9 49.6 85.0 62.3 11.3 53.0 73.3 39.6 69.8 44.7 47.9 84.1 37.0 35.9 105.2 68.7 82.8 89.0 13.7 13.3 19.7 11.4 15.8 13.8 11.7 13.1 15.3 13.5 17.6 13.7 11.1 6.5 21.2 20.3 15.9 11.4 8.3 34.9 35.0 28.1 43.5 36.5 34.1 30.6 31.2 29.7 28.3 33.4 34.3 50.4 32.1 20.7 6.8 59.8 64.6 81.9 18.7 39.3 27.5 37.4 32.1 29.5 24.3 17.5 16.5 6.2 72.5 55.9 63.3 54.8 46.7 8.0 35.4 16.8 37.3 34.6 17.9 10.3 45.8 43.6 30.4 21.9 31.6 32.4 21.5 34.2 18.1 51.0 42.1 8.8 40.6 32.6 37.5 46.4 6.7 25.7 48.3 32.0 6.5 41.1 32.4 62.8 6.0 10.0 67.9 58.3 30.5 35.7 61.6 50.4 47.0 15.7 21.8 46.0 52.4 46.7 64.1 71.6 28.7 57.7 101.8 58.3 27.3 37.6 74.1 BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 44.2;U-937: 75.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" 9.6 6.8 14.4 4.1 17.9 7.3 9.7 18.4 19.8 6.8 30.8 45.1 17.4 6.3 3.9 48.0 9.7 3.8 52.4 16.5 14.3 19.2 324.0 5.2 3.9 14.3 13.8 8.2 7.0 15.5 12.6 0.3 14.4 16.2 19.8 9.3 25.3 4.1 21.5 30.4 28.1 2.2 12.9 7.9 16.6 4.5 16.3 6.1 17.7 22.8 7.1 9.9 14.7 14.2 23.7 2.9 1.2 11.3 1.9 0.1 0.0 2.8 2.2 11.4 6.3 20.5 7.5 0.2 33.0 0.7 0.9 10.3 10.0 5.4 4.2 0.3 0.0 12.0 8.3 7.0 8.3 27.0 12.3 3.4 6.0 4.4 9.4 1.2 2.8 13.7 0.0 8.4 0.2 40.9 20.5 18.8 8.2 44.2 4.2 19.6 4.1 31.5 12.3 9.9 20.1 8.8 8.2 1.1 4.5 0.5 26.3 22.7 0.3 0.7 3.9 0.1 21.6 10.4 20.5 0.3 0.7 75.8 1.5 2.9 1.3 0.6 4.6 0.2 6.4 5.1 5.1 4.2 3.5 4.6 7.6 4.7 0.0 4.5 0.2 3.8 3.7 3.4 14.4 17.9 18.4 19.8 16.5 14.3 14.3 13.8 14.4 12.9 16.3 14.2 0.4 3.2 9.4 27.7 7.0 9.3 8.5 10.0 16.5 21.3 20.3 14.7 36.7 17.2 13.8 12.9 20.9 2.0 7.1 68.9 52.8 6.6 9.5 34.1 3.6 2.2 27.2 6.7 60.5 5.6 5.1 2.8 17.3 16.5 1.3 6.6 5.0 112.3 8.9 18.5 58.0 43.2 10.2 5.4 8.5 13.9 5.6 3.5 16.0 8.4 1.0 17.5 11.3 27.2 12.5 3.0 36.4 4.1 5.4 6.5 62.8 30.2 48.0 33.6 0.0 2.4 3.7 16.8 4.9 36.3 10.9 1.9 8.5 10.0 68.7 13.1 BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;prostate: 3.3;testis: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 8.1;Inhibitory neurons: 6.2;Muller glia cells: 10.7;Spermatogonia: 38.3" "Group enriched" "Detected in some" 43 "prostate cancer: 6.3;testis cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 33.2;HEK 293: 7.9;HEL: 21.1;MOLT-4: 13.1;SuSa: 15.4;U-698: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: AB_10600787" "unprognostic (3.62e-4)" "unprognostic (3.82e-1)" "unprognostic (4.82e-2)" "unprognostic (5.96e-3)" "unprognostic (2.97e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (5.58e-2)" "unprognostic (6.71e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (1.49e-1)" "unprognostic (4.58e-3)" "unprognostic (4.24e-1)" 0.0 0.0 0.7 1.1 0.7 0.8 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.3 1.1 0.0 0.1 0.2 2.1 1.2 3.6 0.1 0.0 0.0 1.0 0.3 2.8 3.3 0.2 1.1 0.0 0.0 0.0 0.0 1.2 0.1 0.1 1.2 0.2 9.4 0.7 1.1 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 33.2 0.0 0.0 0.0 7.9 21.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.0 7.0 0.0 0.1 0.0 0.0 13.1 0.0 6.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 0.8 0.0 0.0 0.0 15.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 1.3 1.3 1.1 1.2 3.6 2.8 0.1 0.7 0.4 0.4 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 3.4 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4.8 2.5 0.0 0.0 3.3 6.2 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.1 10.7 0.0 3.5 0.2 0.0 0.0 0.0 3.9 1.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.6 38.3 0.0 0.0 0.0 1.5 2.2 0.0 0.0 BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Proximal tubular cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cell line enhanced" "Detected in some" "AF22: 3.4;HDLM-2: 11.7;JURKAT: 4.5;MOLT-4: 4.8;REH: 6.5;SH-SY5Y: 2.9" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" 1.7 1.9 5.1 0.7 5.1 1.0 1.8 4.1 7.4 2.8 4.1 3.4 0.4 2.0 1.5 0.6 2.5 2.0 1.6 5.1 4.3 3.4 0.1 0.9 2.1 6.3 5.0 4.4 1.7 1.8 3.4 0.3 6.4 1.5 0.4 3.7 1.0 1.2 2.6 0.8 1.6 0.7 4.1 2.7 1.7 1.0 4.8 4.8 1.8 1.7 1.4 2.2 1.7 5.3 0.0 0.0 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 4.8 0.2 2.6 0.0 0.0 6.5 1.1 0.0 0.0 1.2 1.1 2.9 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.2 1.7 8.0 1.6 1.0 0.2 1.2 0.0 1.7 0.0 0.4 5.1 5.1 4.1 7.4 5.1 4.3 6.3 5.0 6.4 4.1 4.8 5.3 8.7 6.4 3.1 0.0 17.2 1.9 4.6 4.6 1.8 13.3 4.0 16.9 8.6 8.6 6.1 5.5 16.7 0.3 0.6 0.5 54.8 6.4 8.9 2.7 1.9 6.9 12.1 0.8 0.0 1.8 0.5 8.4 2.6 1.3 1.3 10.2 4.6 0.2 0.3 8.4 0.0 0.8 2.0 0.6 4.4 7.1 13.1 1.5 3.6 0.0 0.5 22.7 0.0 0.0 0.0 2.6 4.5 21.4 7.6 1.1 0.2 30.2 6.4 17.8 6.6 6.8 5.6 3.7 9.1 0.3 2.3 0.1 2.8 11.4 1.6 1.9 BHLHA15 "BHLHB8, MIST1" ENSG00000180535 "Basic helix-loop-helix family member a15" Q7RTS1 7 98211439-98215457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 502.8;salivary gland: 145.9" "Cell type enriched" "Detected in single" 25 "Plasma cells: 12.6" "Cancer enriched" "Detected in many" 4 "prostate cancer: 16.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Karpas-707: 53.5;RPMI-8226: 72.0;U-266/70: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034083, HPA047834" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus" "CAB034083: AB_2065216, HPA047834: AB_2680172" "unprognostic (2.80e-2)" "unprognostic (9.45e-3)" "unprognostic (8.10e-2)" "unprognostic (6.66e-2)" "unprognostic (4.33e-3)" "unprognostic (1.10e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (3.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (3.70e-4)" "unprognostic (3.36e-1)" "unprognostic (1.94e-1)" "unprognostic (2.95e-1)" "unprognostic (8.25e-3)" 0.1 0.1 0.8 3.6 0.6 0.3 1.5 0.1 2.0 1.9 0.1 4.0 4.0 0.1 0.8 0.9 0.1 0.7 0.2 1.3 0.9 0.6 5.2 0.9 3.8 0.6 0.5 0.4 502.8 0.1 1.5 0.1 0.6 8.5 1.5 0.0 145.9 3.9 0.2 0.6 3.4 0.0 1.0 5.0 31.3 0.2 1.5 0.7 1.9 0.0 4.7 2.5 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.1 0.8 0.9 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.6 6.7 5.9 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.2 0.0 0.0 53.5 0.0 0.9 0.0 0.0 0.8 6.2 0.8 0.4 0.0 72.0 0.3 0.0 4.3 1.2 0.0 11.2 0.0 0.0 0.7 0.1 0.0 0.0 0.7 0.1 0.1 67.6 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.6 0.1 2.0 1.3 0.9 0.6 0.5 0.6 1.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069767-79090069 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 333.1;liver: 429.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Hepatocytes: 201.2;Proximal tubular cells: 408.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 17.5;Hep G2: 78.2;hTEC/SVTERT24-B: 46.0;U-87 MG: 18.6" "Not detected" "Not detected" HPA044573 Enhanced NA NA 1900000 "Cluster 17: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 31.3 16.6 5.6 3.0 6.0 0.3 15.5 4.5 5.0 8.5 14.2 15.7 1.7 12.1 37.6 7.6 7.6 7.4 13.6 4.9 7.3 333.1 429.9 3.1 1.3 5.2 7.0 7.8 1.8 0.5 12.3 0.4 6.2 12.0 2.4 1.3 2.1 14.4 10.2 2.4 6.1 13.0 4.7 0.6 9.1 3.8 6.9 0.9 18.8 4.8 1.0 18.1 3.8 4.7 0.0 0.2 0.1 0.1 8.5 6.0 2.8 7.8 17.5 4.0 7.7 0.0 0.1 0.1 0.1 9.7 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.4 78.2 6.6 0.4 0.1 7.3 0.0 46.0 0.0 7.9 0.0 0.0 0.4 0.4 1.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 2.2 0.1 0.5 0.0 0.1 0.5 0.1 0.2 0.0 0.3 0.1 0.3 0.1 0.1 0.1 0.3 18.6 0.4 0.1 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.3 0.0 0.1 0.0 0.0 5.6 6.0 4.5 5.0 4.9 7.3 5.2 7.0 6.2 4.7 6.9 4.7 1.4 6.4 0.5 6.2 1.2 0.8 0.4 0.1 0.0 1.5 0.2 0.1 4.4 1.5 0.0 46.0 2.1 0.2 0.0 0.0 95.9 0.1 0.5 0.4 11.7 2.9 1.2 2.7 4.1 0.0 0.4 17.3 0.0 0.4 0.0 4.5 2.5 201.2 0.3 0.0 0.6 0.1 0.0 4.4 1.2 1.3 27.4 2.5 0.0 11.2 0.3 4.2 0.0 2.0 0.6 0.0 0.0 37.2 0.1 0.4 0.0 408.6 0.1 1.2 6.6 6.2 3.1 0.4 0.5 0.1 1.0 0.3 2.2 30.0 0.0 1.0 BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 158.7;Collecting duct cells: 86.5;Ductal cells: 98.5;Fibroblasts: 79.6;Microglial cells: 165.8;Proximal tubular cells: 148.2" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 59.1;BJ hTERT+: 61.4;CACO-2: 93.1;RPTEC TERT1: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" 10.6 6.1 0.3 4.0 0.5 0.3 8.7 0.0 1.6 5.8 1.9 4.5 1.2 4.9 4.0 3.5 7.5 11.6 10.5 0.6 1.0 28.6 2.4 5.8 2.4 1.2 0.6 13.9 16.9 0.8 3.6 3.6 0.2 3.8 4.1 1.4 4.3 4.2 7.6 6.1 2.7 4.7 1.2 2.9 2.7 3.1 0.7 1.4 4.6 6.2 2.7 5.5 5.6 0.7 0.0 59.1 0.8 0.0 17.9 23.0 0.0 38.5 61.4 34.4 40.4 93.1 12.3 0.0 39.8 39.3 8.8 0.8 6.1 7.0 47.4 0.1 5.9 0.0 7.4 0.1 11.5 0.0 0.0 36.0 2.2 26.9 28.6 42.3 0.1 0.0 0.0 0.2 13.4 0.1 0.0 0.0 0.5 0.0 3.8 0.0 14.3 0.0 140.8 7.1 0.2 7.3 0.1 0.4 3.4 2.4 0.0 0.6 0.0 8.2 7.7 1.4 5.0 0.0 0.0 0.1 23.8 0.0 7.8 6.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.5 0.1 0.0 0.3 0.5 0.0 1.6 0.6 1.0 1.2 0.6 0.2 1.2 0.7 0.7 4.1 0.0 0.5 120.5 1.5 7.1 1.3 1.3 0.6 0.6 1.1 4.3 3.3 158.7 1.7 86.5 0.0 0.4 0.1 0.3 78.2 98.5 5.2 43.8 14.4 1.4 3.6 0.0 70.4 3.5 0.2 79.6 0.5 7.2 0.0 4.2 3.3 1.4 3.5 0.0 37.2 1.2 0.0 0.6 18.5 3.2 71.1 1.7 21.4 165.8 1.1 10.1 0.0 25.6 2.7 35.3 1.2 50.0 0.3 2.4 0.0 148.2 14.1 0.2 6.6 40.0 9.8 0.1 3.9 0.3 4.7 4.1 1.5 8.7 1.6 0.1 BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 329.3;Club cells: 215.6;Ionocytes: 443.5;Paneth cells: 140.5;Respiratory ciliated cells: 204.1;Urothelial cells: 175.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 72.9;plasmacytoid DC: 58.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 89.9;CAPAN-2: 44.3;Daudi: 44.2;U-698: 172.1" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051360: AB_2681453" "unprognostic (1.18e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.86e-3)" "unprognostic (3.27e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.45e-5)" "unprognostic (1.38e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (3.04e-1)" 0.2 2.3 0.2 4.1 0.4 4.1 4.9 0.7 0.3 2.8 0.0 8.5 3.6 0.2 1.2 11.3 3.0 3.1 0.3 0.5 0.0 3.8 0.5 1.4 11.6 0.0 0.0 0.3 2.5 1.6 1.0 0.1 0.1 11.4 5.2 0.2 17.5 0.5 0.0 3.5 5.3 0.2 0.0 2.9 13.4 2.0 0.1 1.4 1.8 0.1 11.2 2.6 6.5 0.0 89.9 0.7 0.2 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 28.8 44.3 44.2 4.2 0.0 0.9 19.5 4.8 1.9 0.0 0.7 6.7 0.1 0.6 4.9 0.7 21.2 4.1 0.0 8.8 0.0 0.0 0.3 0.2 9.5 0.3 2.0 0.0 22.9 16.9 28.9 6.7 24.2 7.3 0.2 0.1 20.6 0.9 2.6 1.7 0.0 3.1 8.2 6.5 3.1 1.6 28.9 0.8 0.1 2.4 0.2 1.0 10.4 17.1 172.1 0.0 2.2 0.2 1.8 2.9 72.9 2.7 0.7 4.3 17.1 9.5 4.2 10.4 11.7 6.4 3.5 11.3 0.9 0.8 58.6 7.1 6.3 0.2 0.4 0.7 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 4.2 0.0 9.3 12.6 32.7 329.3 3.4 0.0 39.7 24.1 0.7 17.2 215.6 7.3 0.0 1.4 7.9 43.0 7.9 62.2 0.3 17.7 0.8 2.3 50.6 5.7 0.3 16.2 1.2 0.9 90.7 9.1 0.0 0.1 5.3 0.7 0.9 0.0 0.2 52.9 443.5 1.4 4.8 0.4 0.0 4.0 35.6 0.0 6.4 0.0 1.0 0.0 0.1 105.2 140.5 0.7 79.7 53.1 10.2 15.7 204.1 0.0 0.0 0.0 14.9 0.2 11.0 16.1 11.8 1.0 12.9 0.3 53.9 175.3 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 BLACAT1 "linc-UBC1, LINC00912, onco-lncRNA-30" ENSG00000281406 "Bladder cancer associated transcript 1" 1 205434885-205457091 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.7;epididymis: 3.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 2.9;Collecting duct cells: 5.5;Horizontal cells: 1.7;Pancreatic endocrine cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.2;CAPAN-2: 6.8;NTERA-2: 8.5;SuSa: 4.4;U-2 OS: 4.5" NA NA "Cluster 5: NTERA-2 - Transcription" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (3.01e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-3)" "unprognostic (5.22e-2)" "unprognostic (7.97e-2)" "unprognostic (5.59e-2)" "unprognostic (5.02e-2)" "unprognostic (2.13e-2)" "unprognostic (7.37e-3)" "unprognostic (5.36e-2)" "unprognostic (6.23e-7)" "unprognostic (3.09e-2)" "unprognostic (6.78e-2)" "unprognostic (1.84e-2)" "unprognostic (4.59e-1)" 0.0 0.0 0.5 0.0 0.4 0.0 0.1 5.7 1.3 0.1 0.0 0.0 0.2 0.3 3.8 0.4 1.4 0.3 0.0 0.3 0.4 0.1 0.0 0.2 0.0 3.8 0.7 0.1 0.0 0.0 0.0 4.0 0.1 0.1 0.7 0.6 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.1 1.2 1.4 0.0 1.4 0.0 0.2 0.0 0.6 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 6.8 0.0 1.5 0.0 0.0 1.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 1.1 0.2 0.0 0.9 0.0 0.0 8.5 1.2 0.2 0.0 1.7 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.4 4.4 0.0 0.0 0.0 0.0 4.5 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 5.7 1.3 0.3 0.4 3.8 0.7 4.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.9 0.1 0.1 0.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.8 BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 466.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 358.9" "Low region specificity" "Detected in all" HPA047390 Approved Nucleoli NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "HPA047390: AB_2680025" "unprognostic (1.05e-2)" "unprognostic (7.91e-3)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.08e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (3.51e-1)" "unprognostic (4.45e-1)" "unprognostic (1.91e-3)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.96e-2)" "unprognostic (7.62e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.28e-5)" 65.3 56.2 161.7 27.2 189.7 35.9 59.5 106.0 147.2 49.3 159.6 54.9 51.1 34.5 52.5 86.3 141.0 29.0 75.7 147.4 163.5 60.5 101.0 37.3 40.0 123.5 137.6 40.8 27.3 50.8 149.1 76.0 145.4 59.5 52.2 70.9 57.2 56.3 466.4 88.3 48.0 34.0 108.3 46.8 39.2 30.6 197.8 41.6 45.5 120.2 53.1 72.5 60.0 117.3 138.0 38.8 45.8 48.6 86.2 66.0 63.8 64.3 62.2 56.4 45.5 137.9 109.3 70.7 62.1 90.1 53.7 259.1 34.4 268.1 57.5 14.7 31.5 23.2 94.0 130.5 55.8 46.5 29.9 84.8 283.9 54.3 101.0 46.1 79.6 51.3 22.7 51.9 114.1 77.0 39.0 37.1 36.9 77.6 109.6 36.6 171.0 47.2 64.6 358.9 41.8 50.2 77.3 221.2 54.7 46.5 73.6 44.4 75.2 144.6 37.2 51.3 28.2 28.1 37.5 34.2 60.4 42.4 26.5 74.9 56.6 69.9 45.2 56.0 49.6 93.9 51.3 48.4 52.8 113.6 67.1 52.6 59.3 48.2 53.8 22.6 55.4 52.8 161.7 189.7 106.0 147.2 147.4 163.5 123.5 137.6 145.4 108.3 197.8 117.3 24.4 80.1 31.0 14.0 38.4 147.0 97.3 135.9 137.1 43.0 29.0 60.8 56.8 30.0 68.7 40.5 22.9 115.1 25.5 72.4 82.2 35.7 73.7 58.8 26.3 54.0 40.9 15.6 26.8 33.9 84.8 29.5 17.9 18.1 29.2 32.1 89.6 81.0 55.8 42.1 29.8 58.8 52.9 41.9 36.2 161.7 29.8 29.1 35.6 13.1 30.1 64.0 24.7 16.6 11.4 54.0 31.4 59.5 16.5 88.6 69.9 55.7 63.2 36.2 32.9 28.6 27.0 30.8 27.1 66.8 122.9 65.0 26.1 54.0 33.3 133.4 BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 259.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol NA NA 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450" "unprognostic (2.47e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.16e-3)" "unprognostic (6.45e-3)" "unprognostic (5.01e-2)" "unprognostic (1.63e-2)" "prognostic favorable (8.65e-4)" "unprognostic (1.42e-1)" "unprognostic (1.75e-2)" "unprognostic (2.93e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (5.63e-3)" "unprognostic (3.18e-1)" "unprognostic (2.13e-3)" "unprognostic (4.56e-2)" 53.2 28.0 31.4 39.7 33.4 65.6 49.9 32.0 40.1 44.3 31.4 61.4 12.5 38.5 129.9 67.5 40.9 33.4 52.7 32.3 34.7 41.3 14.6 62.7 58.6 34.1 33.6 46.6 23.5 54.9 26.2 28.9 34.2 38.4 19.8 25.4 36.5 46.0 59.7 33.4 27.7 54.1 33.1 82.0 35.3 13.1 34.0 43.0 31.3 69.3 52.6 43.5 40.4 32.0 48.6 92.2 26.2 110.5 55.0 72.7 1.3 32.3 99.3 54.0 65.4 22.2 28.3 0.3 60.6 51.5 190.7 62.1 82.1 81.7 46.2 227.3 56.8 104.1 86.6 138.1 139.5 11.8 37.5 49.9 135.7 57.2 37.8 108.5 92.7 51.1 70.2 55.7 41.4 52.5 37.0 6.3 35.9 11.0 104.7 80.4 45.6 261.4 121.1 26.6 34.0 104.4 65.9 65.1 55.2 46.2 146.7 77.7 57.0 49.3 53.9 21.8 56.0 74.7 63.2 0.2 80.8 46.9 78.4 51.1 291.9 169.2 39.1 374.9 36.7 26.9 75.7 64.9 135.4 17.0 39.7 31.0 26.5 22.4 368.4 20.1 82.2 208.5 31.4 33.4 32.0 40.1 32.3 34.7 34.1 33.6 34.2 33.1 34.0 32.0 22.0 60.9 85.0 7.5 10.7 29.1 64.2 102.4 34.1 18.0 29.6 36.1 59.4 17.2 75.7 35.0 2.1 9.7 9.3 0.3 56.7 52.6 0.7 31.6 20.2 27.3 0.0 74.7 8.4 35.1 8.1 39.7 8.2 41.4 111.5 17.2 24.3 1.9 259.1 8.4 11.5 0.4 59.0 136.5 53.7 1.6 37.0 80.4 46.2 2.8 147.3 36.6 13.4 7.5 4.3 25.2 1.2 29.0 16.6 87.9 7.1 110.5 69.6 13.0 46.0 23.0 50.6 3.0 14.2 52.9 34.4 5.2 23.4 4.9 0.6 48.7 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Astrocytes: 46.7;Leydig cells: 90.1;Microglial cells: 230.5;Peritubular cells: 67.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Cell line enhanced" "Detected in many" "HSkMC: 31.9;Karpas-707: 40.4;RPMI-8226: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" 5.6 1.0 1.4 3.7 2.5 0.7 3.3 2.3 4.4 12.1 8.2 10.1 1.3 26.9 2.1 4.6 18.4 7.2 2.9 2.6 2.7 6.4 0.3 3.1 0.8 4.7 6.0 31.7 0.5 2.9 1.7 3.4 3.9 3.7 3.0 0.8 1.3 4.8 3.5 3.4 3.3 31.7 3.5 0.7 3.0 6.9 4.7 2.5 2.1 1.9 1.1 6.3 5.8 4.9 0.3 1.7 1.2 0.1 17.5 21.1 2.7 11.4 19.5 7.8 6.4 0.1 0.0 0.0 3.7 7.8 5.8 0.1 5.1 0.0 7.9 0.2 2.0 0.1 5.3 0.0 13.4 0.1 0.5 31.9 0.0 16.6 0.1 13.7 18.0 0.0 0.0 40.4 11.1 0.0 0.0 2.8 6.6 0.1 10.2 0.0 12.5 28.0 6.0 0.3 0.2 1.0 0.1 0.1 18.6 8.3 0.1 0.0 17.7 18.6 13.5 15.1 20.9 0.2 0.0 0.1 7.6 2.5 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 1.5 1.4 2.5 2.3 4.4 2.6 2.7 4.7 6.0 3.9 3.5 4.7 4.9 5.5 0.0 2.2 46.7 0.0 10.1 0.6 0.0 33.6 8.2 0.2 0.4 4.8 0.0 0.6 0.0 0.0 3.2 10.7 0.1 0.0 1.0 7.2 2.2 9.1 10.5 0.0 0.0 1.6 0.4 1.2 38.6 3.1 2.0 22.2 25.1 10.4 0.3 7.3 0.0 1.9 1.1 6.1 1.6 2.3 4.5 90.1 4.2 10.6 230.5 0.1 2.6 30.9 1.0 1.6 0.1 0.0 67.7 3.9 0.7 5.7 35.5 0.7 0.3 6.6 31.5 5.1 0.9 13.5 5.7 5.5 1.2 3.1 36.5 1.8 0.1 BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;intestine: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 266.7;Excitatory neurons: 333.7;Inhibitory neurons: 129.7;Oligodendrocyte precursor cells: 1079.2" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" 0.3 1.7 19.8 0.6 16.8 0.0 1.4 18.7 19.2 0.2 0.0 6.6 4.6 0.2 3.0 1.7 0.4 1.6 5.3 27.1 25.8 2.3 0.0 1.2 0.0 12.5 15.7 0.0 0.0 0.0 0.2 0.0 12.4 6.8 6.7 0.7 1.6 5.1 0.1 0.1 17.9 0.6 13.1 0.0 0.2 3.4 26.0 0.1 2.1 0.0 0.1 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 16.8 18.7 19.2 27.1 25.8 12.5 15.7 12.4 13.1 26.0 10.4 0.0 0.0 0.0 266.7 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.4 2.3 0.0 0.0 3.7 0.0 0.0 0.0 2.0 3.9 0.0 63.3 0.0 0.0 0.1 1.2 0.0 333.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 129.7 2.8 0.0 0.0 0.0 10.5 0.0 0.1 0.0 8.4 0.0 0.0 0.0 1079.2 4.3 0.0 10.8 0.0 0.0 1.0 8.1 0.3 0.0 0.1 0.0 0.0 5.8 2.0 0.7 0.1 0.0 0.0 0.0 0.0 5.2 0.1 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C10orf99 "AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833" ENSG00000188373 "Chromosome 10 open reading frame 99" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 193.2;intestine: 274.9;vagina: 115.3" "Group enriched" "Detected in some" 11 "Distal enterocytes: 853.2;Intestinal goblet cells: 267.6;Paneth cells: 815.9;Proximal enterocytes: 364.8;Undifferentiated cells: 402.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 52.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" 0.4 0.0 0.0 16.8 0.0 0.0 0.5 0.0 0.0 46.7 0.0 268.5 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 274.9 0.1 21.7 2.6 0.0 38.5 21.5 13.1 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 17.4 33.5 115.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.8 1.2 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.1 853.2 0.0 0.0 0.4 3.3 0.8 0.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 267.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 815.9 0.0 0.0 1.0 364.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 46.0 2.3 0.0 1.4 0.0 402.8 46.4 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C11orf52 "FLJ25219, MGC14839" ENSG00000149300 "Chromosome 11 open reading frame 52" Q96A22 11 111918032-111926871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.8;Breast glandular cells: 3.3;Cholangiocytes: 2.8;Endometrial ciliated cells: 3.1;Gastric mucus-secreting cells: 4.1;Respiratory ciliated cells: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CAPAN-2: 23.5;Hep G2: 18.2;MCF7: 17.6;RPTEC TERT1: 27.1;SK-BR-3: 22.9;T-47d: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038387, HPA038388" Uncertain Enhanced "Cell Junctions" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions" "HPA038387: AB_10670167, HPA038388: AB_2675987" "unprognostic (1.30e-2)" "unprognostic (1.13e-1)" "unprognostic (5.84e-4)" "unprognostic (1.48e-4)" "unprognostic (2.57e-1)" "unprognostic (8.04e-2)" "unprognostic (6.77e-2)" "unprognostic (2.07e-2)" "unprognostic (2.26e-1)" "unprognostic (2.77e-1)" "unprognostic (3.80e-1)" "unprognostic (5.38e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" 3.3 0.7 1.0 0.4 0.9 0.0 25.9 4.1 1.3 3.8 2.2 5.2 10.4 2.3 23.7 6.4 17.7 12.3 3.2 0.9 0.9 43.9 22.8 9.7 0.1 1.1 1.0 1.5 25.8 30.8 16.4 10.1 1.7 15.4 6.2 0.1 26.8 10.2 9.3 9.7 9.2 0.8 1.1 0.9 20.9 1.0 1.1 1.0 20.1 8.3 1.3 4.6 3.2 1.5 4.3 0.0 0.0 0.0 2.9 0.4 17.7 1.0 0.8 0.1 0.0 6.8 23.5 0.0 10.6 2.3 0.0 5.4 0.0 1.4 0.1 0.0 0.7 0.0 0.5 18.2 0.0 0.0 0.0 0.3 5.2 0.0 0.2 0.2 1.0 0.0 0.0 0.0 1.5 17.6 0.0 0.2 0.1 12.5 1.8 0.0 1.5 0.0 27.1 15.6 1.2 0.0 0.0 22.9 0.0 2.4 76.5 1.6 2.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 4.1 1.3 0.9 0.9 1.1 1.0 1.7 1.1 1.1 1.5 0.0 6.4 2.8 0.0 0.0 0.1 1.6 0.2 1.2 0.0 3.3 0.9 0.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 3.1 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.5 4.1 1.9 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.9 1.3 6.7 0.0 0.0 0.3 0.3 0.1 0.1 0.6 0.3 1.4 0.0 0.2 0.2 0.7 C11orf95 MGC3032 ENSG00000188070 "Chromosome 11 open reading frame 95" C9JLR9 11 63759892-63768775 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045002 Approved "Intermediate filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Intermediate filaments" "HPA045002: AB_2679179" "unprognostic (4.23e-3)" "unprognostic (7.24e-3)" "unprognostic (6.47e-2)" "unprognostic (9.01e-3)" "unprognostic (7.54e-2)" "unprognostic (3.89e-1)" "unprognostic (8.94e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" "unprognostic (8.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.52e-3)" "unprognostic (1.85e-2)" "unprognostic (6.60e-2)" "unprognostic (5.68e-2)" "unprognostic (1.31e-3)" 12.4 7.1 13.6 5.1 13.5 2.0 9.6 8.4 17.6 16.4 3.8 13.7 3.8 20.3 6.8 4.9 13.6 6.9 9.6 16.1 15.3 12.0 9.6 5.8 6.0 9.0 8.9 22.8 8.7 5.3 11.4 11.0 7.1 8.8 3.5 4.2 6.8 10.1 7.7 4.6 7.5 11.3 7.0 6.7 7.3 4.8 15.2 8.2 11.4 5.4 5.5 12.1 11.3 9.3 3.5 4.6 34.7 11.6 17.7 20.3 5.5 13.0 9.3 6.0 4.2 11.4 2.2 11.2 18.6 12.6 4.5 7.9 15.2 5.2 6.8 11.0 10.3 7.5 8.9 5.2 6.2 3.6 6.0 15.2 1.8 9.9 3.2 19.8 13.5 10.0 9.7 5.0 9.7 4.6 13.6 18.5 16.2 2.1 13.4 31.9 6.6 3.5 8.7 4.4 14.6 30.8 6.2 6.6 18.3 14.1 9.3 8.8 21.3 12.2 11.4 15.7 7.6 4.5 6.3 13.5 3.3 9.1 6.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 13.6 13.5 8.4 17.6 16.1 15.3 9.0 8.9 7.1 7.0 15.2 9.3 8.0 0.0 5.3 6.8 2.2 5.1 1.3 2.8 3.4 4.6 6.3 9.5 7.2 11.5 2.3 0.0 0.0 6.4 2.6 1.0 3.9 2.6 0.3 2.8 11.8 9.0 4.9 0.8 3.9 2.2 0.5 11.3 0.5 4.9 1.3 8.6 13.9 7.0 1.7 6.7 3.0 2.7 4.1 1.6 6.3 1.3 18.3 2.0 3.6 3.7 3.8 11.8 0.0 2.5 0.5 2.1 1.2 7.9 0.7 1.5 0.7 3.6 1.5 3.1 13.1 6.8 11.2 0.4 4.2 1.4 3.4 1.5 1.1 2.3 2.5 1.0 C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Bipolar cells: 57.8;Endometrial ciliated cells: 55.2;Horizontal cells: 63.9;Skeletal myocytes: 44.9" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 49.9;SCLC-21H: 52.5;SH-SY5Y: 52.0;U-87 MG: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" 5.9 14.0 57.3 3.2 58.1 0.1 6.9 62.8 69.1 23.3 20.5 23.8 2.1 26.2 14.2 7.1 22.5 5.0 4.1 74.7 52.5 9.9 4.1 18.4 0.8 53.6 49.8 5.2 3.2 0.1 38.8 0.8 50.9 9.5 4.4 12.8 3.0 19.8 3.0 13.8 14.2 22.3 51.2 6.2 15.7 1.3 55.8 3.1 2.4 6.6 1.2 8.5 11.9 56.1 0.0 6.4 30.8 9.7 22.0 22.0 0.1 10.6 23.8 13.6 8.3 0.1 0.1 0.0 2.4 23.8 9.0 0.7 3.7 0.8 11.7 0.0 1.4 0.1 1.2 0.1 2.7 0.0 0.2 12.0 1.2 12.7 1.0 0.0 0.2 3.0 0.0 0.1 6.3 49.9 0.8 0.1 15.0 0.0 0.0 28.5 5.0 0.1 11.0 22.4 52.5 52.0 8.3 1.0 1.5 8.3 28.9 1.4 0.0 10.8 6.5 18.0 0.0 0.0 0.0 0.1 46.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.2 57.3 58.1 62.8 69.1 74.7 52.5 53.6 49.8 50.9 51.2 55.8 56.1 4.8 38.5 10.6 14.7 0.4 2.7 3.7 5.9 5.2 57.8 0.7 7.1 1.9 1.5 3.9 7.3 20.9 0.3 0.2 0.0 5.9 5.8 3.0 55.2 23.8 8.6 9.0 0.0 20.3 0.2 1.0 16.6 2.0 6.8 1.3 5.4 19.2 4.0 0.3 63.9 11.2 0.1 4.1 0.6 7.1 3.0 15.8 0.5 8.8 7.5 0.1 4.0 0.0 11.1 24.7 1.2 0.1 13.5 0.1 2.1 0.0 0.0 13.6 6.1 0.0 44.9 4.4 0.3 0.6 6.8 7.7 0.3 1.0 0.6 0.1 2.3 C15orf62 LOC643338 ENSG00000188277 "Chromosome 15 open reading frame 62" A8K5M9 15 40769980-40772449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.0;skin 1: 17.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 3.6;Club cells: 5.0;Glandular and luminal cells: 6.3;Ionocytes: 6.1;Prostatic glandular cells: 5.5;Squamous epithelial cells: 4.7;Urothelial cells: 11.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.7;SK-BR-3: 5.7" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Low region specificity" "Detected in all" HPA044636 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "HPA044636: AB_10794052" "unprognostic (9.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.52e-1)" "unprognostic (2.83e-2)" "unprognostic (5.56e-2)" "unprognostic (2.24e-2)" "unprognostic (5.37e-3)" "unprognostic (7.68e-3)" "unprognostic (1.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (1.60e-1)" "unprognostic (3.40e-1)" 1.8 1.3 0.7 1.5 1.0 1.7 2.3 4.4 1.5 3.5 0.0 2.0 1.9 1.7 0.1 26.0 2.1 1.3 1.4 0.7 0.2 2.0 4.0 1.8 2.1 0.7 0.5 2.5 2.0 0.1 2.1 0.4 0.8 2.4 0.1 2.4 8.3 0.1 2.0 17.1 2.6 0.0 0.1 2.3 1.9 0.6 0.8 0.7 2.0 0.1 5.0 1.8 6.9 1.2 0.5 0.4 1.6 2.0 0.6 0.1 0.4 0.7 0.1 0.0 0.2 1.9 2.2 1.0 1.8 0.0 1.3 4.1 0.7 0.0 0.0 1.5 1.6 1.0 4.4 0.6 0.0 0.9 1.2 0.2 0.8 0.0 0.1 1.8 0.6 0.7 0.9 1.2 0.0 0.5 1.3 1.6 0.7 2.8 0.8 1.4 0.3 0.5 17.7 1.5 3.6 0.8 0.6 5.7 0.2 0.6 2.0 1.3 0.8 2.0 0.9 1.8 0.6 1.4 1.0 0.9 0.6 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.4 1.5 0.7 0.2 0.7 0.5 0.8 0.1 0.8 1.2 0.2 0.0 0.0 0.3 0.3 0.0 3.6 2.1 0.6 0.3 1.7 0.6 0.7 0.0 5.0 0.0 0.0 0.1 0.2 0.1 0.0 0.5 0.0 1.6 0.9 0.3 0.0 0.0 0.1 0.2 0.0 0.2 0.0 6.3 0.0 0.1 0.0 0.8 0.2 3.3 0.1 0.1 6.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.1 0.0 0.0 5.5 0.3 0.3 1.3 0.5 0.0 0.0 0.3 0.0 0.0 4.7 1.0 0.0 0.2 0.0 0.3 11.6 C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 108.3;thyroid gland: 228.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 268.1;Club cells: 70.4;Distal tubular cells: 113.5;Fibroblasts: 43.8" "Group enriched" "Detected in many" 14 "lung cancer: 64.7;thyroid cancer: 145.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;Hep G2: 2.5;HHSteC: 1.3;NTERA-2: 1.7;U-2197: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" NA NA 1400000 "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA013613: AB_1845584, HPA016934: AB_2732417" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (6.29e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (9.23e-2)" "unprognostic (2.65e-1)" "unprognostic (6.39e-2)" "unprognostic (3.25e-2)" "unprognostic (6.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (8.48e-3)" 17.8 4.2 20.0 6.0 21.6 0.2 12.8 18.8 28.3 20.2 15.0 6.3 17.6 3.5 87.1 6.7 12.4 45.0 18.8 19.4 19.9 16.8 0.3 108.3 0.9 19.9 18.5 2.8 5.4 0.1 5.7 0.9 19.0 4.2 5.0 0.5 35.0 1.1 0.2 0.6 7.9 4.9 19.6 0.6 82.4 1.2 22.6 2.8 228.8 3.9 2.2 14.4 3.2 22.7 0.0 0.1 0.0 0.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.6 2.5 1.3 0.1 0.2 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.7 0.3 1.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.5 0.3 0.1 0.0 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.0 20.0 21.6 18.8 28.3 19.4 19.9 19.9 18.5 19.0 19.6 22.6 22.7 0.9 44.8 268.1 23.2 0.0 0.4 1.8 0.3 0.6 0.5 23.6 18.0 2.8 0.0 70.4 0.0 0.0 0.1 0.1 0.1 113.5 0.0 1.7 3.7 0.4 1.3 0.0 0.0 0.9 7.8 0.1 43.8 17.3 0.3 5.1 0.0 0.0 0.0 6.0 0.0 0.7 0.6 6.1 0.0 0.4 2.7 9.3 0.7 0.0 11.2 0.0 0.3 0.0 1.0 1.6 0.7 0.4 14.7 0.0 5.0 0.0 1.5 16.9 0.2 0.0 1.9 1.9 0.8 0.1 0.6 0.3 0.3 0.6 0.0 0.7 5.0 C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 515.3;skin 1: 331.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2060.3;Pancreatic endocrine cells: 2590.4;Paneth cells: 1697.3;Proximal enterocytes: 1756.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.2" "Cell line enhanced" "Detected in many" "A-431: 745.5;A549: 1228.0;CAPAN-2: 767.1;HBEC3-KT: 744.6;hTCEpi: 799.2;OE19: 678.3;PC-3: 659.8" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" 43.1 5.0 2.8 17.6 3.1 3.6 25.5 2.9 4.4 82.4 2.9 187.5 186.7 6.1 0.6 515.3 91.5 49.5 32.9 2.3 2.6 28.2 1.3 91.3 0.9 3.1 3.0 4.6 8.9 0.5 12.7 7.9 3.4 26.2 104.1 0.1 123.3 18.3 3.9 331.1 189.5 4.0 2.5 10.7 151.5 1.5 3.8 4.1 18.9 4.3 30.8 102.2 224.3 2.5 745.5 1228.0 0.0 0.6 0.0 0.0 1.2 1.0 0.0 0.0 0.0 77.1 767.1 0.0 394.2 0.0 0.7 300.1 0.0 744.6 0.0 0.4 0.5 0.4 244.2 20.0 5.4 0.0 0.2 0.0 799.2 0.3 493.3 3.3 10.2 0.9 0.4 0.5 0.8 220.4 0.1 1.9 0.4 678.3 659.8 0.2 0.2 2.8 469.5 255.2 0.8 0.8 416.6 340.8 0.8 1.6 103.7 2.3 141.6 0.5 201.9 0.7 2.8 0.7 2.4 3.7 0.1 0.2 0.2 2.1 0.6 2.2 0.2 0.0 0.4 0.1 0.5 0.1 22.2 1.4 0.7 0.3 1.0 0.4 0.1 1.8 0.0 18.2 2.8 3.1 2.9 4.4 2.3 2.6 3.1 3.0 3.4 2.5 3.8 2.5 29.1 535.2 172.9 0.0 5.4 225.3 28.4 508.7 436.5 0.0 32.5 25.5 2.4 267.4 418.0 55.2 0.0 8.6 1.7 2060.3 1.9 207.7 0.7 144.3 26.0 18.4 76.1 3.6 0.1 753.8 1.3 44.7 353.7 273.2 38.2 3.7 3.6 0.4 1.3 0.0 0.0 842.0 99.7 1.4 15.1 5.1 4.1 32.9 1.8 0.0 4.9 0.0 0.0 0.0 0.0 2590.4 1697.3 0.0 5.7 35.7 1756.4 51.7 212.5 0.0 0.0 0.4 14.3 1.8 1.9 629.0 348.4 3.1 7.9 0.0 691.9 188.4 C19orf81 ENSG00000235034 "Chromosome 19 open reading frame 81" C9J6K1 19 50649445-50659310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 2.4;testis: 6.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 20.2;Early spermatids: 30.7;Muller glia cells: 65.4;Rod photoreceptor cells: 29.3;Spermatocytes: 17.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 4.3;HMC-1: 1.5;JURKAT: 1.2;K-562: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060238 Enhanced Approved Vesicles,Aggresome NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Vesicles, Aggresome" "HPA060238: AB_2684228" "unprognostic (2.29e-2)" "unprognostic (2.75e-2)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (3.39e-2)" "unprognostic (2.03e-2)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.48e-2)" "unprognostic (6.01e-4)" "unprognostic (4.41e-1)" "unprognostic (1.17e-2)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (1.95e-1)" "unprognostic (5.04e-2)" 0.0 0.0 0.6 0.0 0.5 0.1 0.0 2.4 1.3 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.3 0.1 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.5 4.3 0.4 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 1.2 1.0 0.8 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 2.4 1.3 0.8 0.6 0.7 0.4 0.8 0.2 0.4 0.8 0.2 0.0 0.0 0.3 0.5 2.2 1.7 0.0 12.0 14.9 4.0 4.3 1.3 1.5 0.0 20.2 8.4 0.1 3.0 0.1 13.7 7.9 30.7 2.3 1.4 1.5 0.0 0.8 1.5 1.3 0.3 0.9 0.0 5.4 0.0 1.4 1.8 0.0 0.9 11.8 2.1 0.0 0.0 0.3 0.8 6.4 0.6 0.9 5.4 1.0 2.6 65.4 0.0 1.5 3.5 4.4 0.0 0.7 0.1 6.0 0.0 0.2 0.0 29.3 0.0 1.1 1.8 17.1 5.0 0.9 4.3 0.0 0.8 2.7 0.0 0.4 C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 120.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.8;Hepatocytes: 121.3;Proximal enterocytes: 255.7;Syncytiotrophoblasts: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 62.4;HUVEC TERT2: 49.7;TIME: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" 50.0 6.8 32.3 6.8 43.4 0.3 28.4 10.8 45.8 14.8 17.3 30.9 112.4 12.5 21.3 5.7 14.4 10.3 18.9 47.5 11.5 52.8 101.4 23.4 8.5 13.1 10.5 17.9 12.1 20.5 17.5 70.2 13.5 31.1 23.3 8.9 74.1 10.6 14.6 9.1 120.9 11.8 10.0 50.0 22.4 7.2 15.9 3.8 16.5 19.3 9.5 6.9 7.2 25.9 1.6 7.3 0.5 10.1 0.0 0.0 29.0 2.0 8.1 4.2 18.3 7.3 7.6 0.0 3.1 0.6 8.5 0.2 16.9 3.4 3.8 0.0 16.9 0.2 1.5 62.4 9.4 0.0 0.2 1.3 5.7 0.3 2.1 0.0 49.7 0.0 4.7 0.0 0.3 6.7 0.0 0.5 12.3 20.4 5.2 0.0 0.1 0.6 9.0 9.8 5.3 7.4 0.0 12.3 30.9 17.5 20.0 0.4 93.6 0.0 0.1 0.3 1.7 1.1 0.0 0.0 0.2 0.0 1.5 0.0 0.2 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 43.4 10.8 45.8 47.5 11.5 13.1 10.5 13.5 10.0 15.9 25.9 76.7 3.2 6.7 1.6 5.8 3.4 4.2 1.4 1.8 17.3 29.8 20.4 19.5 17.2 5.1 31.3 6.2 74.4 0.9 109.8 39.2 9.7 1.5 7.6 1.3 51.5 8.4 8.0 20.7 16.6 68.2 5.6 2.0 11.7 0.0 59.0 18.9 121.3 6.4 0.0 2.0 25.6 6.1 4.7 2.7 2.8 3.1 1.4 8.8 5.6 4.8 10.4 0.0 0.0 1.4 13.9 55.5 19.2 0.0 11.0 255.7 58.2 1.9 3.9 0.0 2.1 4.6 0.5 5.5 0.8 1.7 183.9 1.2 54.9 25.1 2.6 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 14.9;Glandular and luminal cells: 28.4;Squamous epithelial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" 0.6 0.9 0.7 2.4 0.7 1.1 2.2 1.8 0.7 0.9 0.2 1.6 1.3 0.8 2.0 4.0 1.1 0.9 1.5 0.7 0.9 1.9 1.7 0.9 4.3 0.8 0.8 0.9 0.8 1.2 0.8 1.1 0.8 1.6 2.0 0.9 1.9 0.9 1.0 6.7 2.8 0.6 0.7 4.2 1.7 1.3 1.1 2.1 1.2 0.9 2.4 1.9 1.7 0.8 4.7 2.4 1.5 0.8 2.0 2.3 3.5 2.6 3.4 3.1 3.2 4.9 3.5 4.9 1.5 1.7 1.9 9.3 0.9 7.6 3.6 4.9 3.1 3.2 1.7 0.4 2.8 4.6 1.4 1.4 6.6 3.9 6.3 2.6 1.8 6.6 6.5 3.5 2.7 2.4 3.9 4.7 6.4 3.2 4.1 4.0 7.2 6.9 2.7 4.0 6.0 6.5 3.5 2.7 4.0 3.4 4.2 2.4 1.7 2.6 3.1 2.7 4.2 3.2 3.4 5.4 2.3 3.7 3.8 4.7 0.8 0.7 1.3 0.9 0.9 1.8 0.6 1.0 1.6 3.7 1.1 1.2 0.5 1.5 0.5 2.7 0.6 0.9 0.7 0.7 1.8 0.7 0.7 0.9 0.8 0.8 0.8 0.7 1.1 0.8 0.6 3.2 2.2 0.0 1.1 2.2 6.1 4.6 6.8 1.6 3.7 2.8 2.0 0.0 1.8 0.0 0.0 3.9 1.5 3.5 7.9 1.9 0.1 14.9 1.8 0.8 3.6 2.1 0.5 2.0 5.0 0.9 2.6 28.4 1.3 2.2 1.4 2.3 2.8 1.7 0.6 5.9 0.0 1.3 0.3 0.6 2.5 1.6 0.0 1.0 1.3 2.2 0.0 0.0 0.3 4.1 3.5 0.0 0.6 5.1 2.4 7.4 1.8 1.3 0.0 0.4 1.0 3.6 4.7 25.0 4.8 4.0 1.1 2.8 3.4 12.1 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Cell type enriched" "Detected in some" 7 "Horizontal cells: 673.0" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 34.8;SH-SY5Y: 24.8;U-2 OS: 89.0;U-251 MG: 28.1;U-87 MG: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" 7.7 0.7 18.5 0.4 17.2 0.0 0.9 26.6 32.1 3.0 16.2 4.9 2.0 13.0 0.3 1.8 4.4 0.3 4.1 15.5 21.4 21.0 0.7 0.2 0.0 134.0 41.9 0.7 4.6 0.0 2.1 0.0 24.9 7.3 0.3 8.1 0.7 0.0 0.1 0.5 6.2 0.6 32.4 0.1 3.9 0.8 21.6 0.1 0.3 0.2 0.0 6.4 1.2 24.3 4.6 5.1 1.1 17.8 0.3 0.0 0.3 0.8 0.7 0.5 1.6 0.7 0.6 0.2 3.0 0.4 5.3 0.6 2.8 0.2 0.2 12.7 7.5 0.0 7.9 0.1 2.1 0.0 2.2 0.4 0.0 0.7 0.2 6.2 0.0 3.1 0.1 0.2 0.5 1.1 4.0 0.1 3.1 0.5 10.7 6.7 0.2 0.3 0.1 0.4 34.8 24.8 15.6 1.3 1.3 0.9 4.1 0.2 0.1 1.4 89.0 0.9 28.1 1.0 0.0 0.1 27.8 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 17.2 26.6 32.1 15.5 21.4 134.0 41.9 24.9 32.4 21.6 24.3 0.1 0.0 0.0 4.2 0.0 0.3 0.2 1.0 0.0 22.3 0.4 3.2 1.1 5.7 0.0 0.0 10.4 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.4 5.3 0.0 0.5 0.0 0.1 1.9 0.0 0.5 0.0 0.3 1.1 0.1 0.0 673.0 11.7 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 1.0 0.0 17.6 0.0 84.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.7 0.2 1.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C20orf194 DKFZp434N061 ENSG00000088854 "Chromosome 20 open reading frame 194" Q5TEA3 20 3249306-3407669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 226.9;Cone photoreceptor cells: 202.3;Excitatory neurons: 205.6;Inhibitory neurons: 163.1;Oligodendrocyte precursor cells: 135.7;Oligodendrocytes: 191.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052103, HPA067418" Approved Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Cytosol" "HPA052103: AB_2681727, HPA067418: AB_2685835" "unprognostic (9.77e-2)" "unprognostic (8.39e-2)" "unprognostic (5.03e-3)" "unprognostic (1.83e-1)" "unprognostic (1.18e-1)" "unprognostic (4.26e-2)" "unprognostic (1.66e-2)" "unprognostic (7.64e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.97e-1)" "prognostic favorable (7.68e-4)" "unprognostic (9.58e-3)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (7.52e-2)" 11.8 9.5 19.7 5.2 22.4 3.6 8.7 18.5 20.1 10.1 6.8 14.4 4.1 10.4 5.4 8.4 9.8 8.3 15.3 19.5 21.4 11.2 2.6 10.0 4.5 21.5 22.9 12.3 6.3 4.2 8.8 9.1 21.1 8.6 4.3 16.4 5.8 11.6 32.3 5.6 6.6 12.9 19.6 7.3 9.7 10.4 21.8 3.8 9.6 11.6 2.9 12.6 8.9 26.0 4.0 3.6 9.7 4.7 19.7 21.6 1.1 9.2 10.3 6.0 7.5 0.0 4.3 0.0 2.5 12.3 7.7 4.7 3.7 9.1 8.2 0.9 1.8 1.1 1.4 10.0 9.2 1.2 0.5 17.7 6.9 7.9 6.8 8.6 12.2 3.5 2.0 0.0 8.9 1.8 2.5 6.5 2.9 2.2 2.3 2.9 8.8 0.1 7.8 8.1 1.9 5.7 4.1 7.2 12.0 8.3 6.8 11.3 13.7 7.5 3.2 4.7 4.5 0.1 0.0 0.0 2.4 1.2 5.8 0.4 0.8 0.0 0.5 0.4 0.2 0.2 0.3 0.4 0.9 0.4 0.1 0.3 0.0 0.0 0.4 1.0 0.4 0.2 19.7 22.4 18.5 20.1 19.5 21.4 21.5 22.9 21.1 19.6 21.8 26.0 23.6 28.9 9.2 226.9 3.7 6.9 6.7 10.8 8.6 35.1 10.1 10.8 28.5 15.7 10.3 12.9 202.3 1.8 8.9 0.1 1.9 9.1 31.8 10.6 15.9 20.1 0.0 4.0 205.6 4.7 5.4 13.4 19.4 12.1 14.0 53.3 25.7 2.3 19.6 30.3 163.1 0.5 4.1 34.0 25.5 8.9 19.9 22.4 8.8 89.9 14.1 10.0 3.1 135.7 191.2 9.4 14.8 13.5 1.5 5.4 7.4 8.4 21.8 13.9 13.1 18.4 22.2 28.5 25.0 7.2 5.7 1.8 7.8 16.4 1.4 5.2 C22orf23 "EVG1, FLJ32787, LOC84645" ENSG00000128346 "Chromosome 22 open reading frame 23" Q9BZE7 22 37943050-37953669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 95.5" "Group enriched" "Detected in some" 7 "Early spermatids: 292.5;Late spermatids: 312.9;Spermatocytes: 241.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 31.8;U-138 MG: 31.4;U-87 MG: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000650 Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA000650: AB_2732391" "unprognostic (6.09e-3)" "unprognostic (3.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.95e-1)" "unprognostic (1.80e-1)" "unprognostic (7.42e-5)" "unprognostic (1.50e-2)" "unprognostic (2.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.04e-1)" "unprognostic (5.80e-2)" "unprognostic (8.18e-3)" "unprognostic (4.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.82e-2)" "unprognostic (8.46e-2)" 2.9 2.6 3.9 5.6 8.8 3.0 0.8 9.5 5.1 1.7 4.7 3.4 2.9 8.3 1.3 14.0 12.4 6.4 5.1 4.7 7.7 2.3 0.4 5.0 3.6 12.8 10.4 2.5 8.6 1.1 4.8 5.3 11.0 5.0 0.1 3.5 10.3 0.2 5.7 26.0 3.8 0.1 8.2 2.3 9.0 95.5 9.7 0.2 8.2 0.0 0.1 6.2 1.2 16.1 6.6 5.3 11.1 10.3 0.2 0.4 13.7 18.4 0.5 0.5 0.7 6.3 5.9 3.5 5.0 0.4 11.7 31.8 0.4 0.1 0.6 6.7 13.4 2.0 4.6 4.3 0.5 5.4 4.4 0.4 0.2 2.2 0.2 15.4 0.1 2.6 2.3 2.0 0.1 4.1 0.3 3.2 1.6 6.6 4.6 6.0 16.1 1.3 0.1 29.4 5.6 4.0 8.2 3.2 10.3 17.5 3.6 7.3 27.8 31.4 10.2 25.1 10.0 4.6 2.0 1.6 46.9 2.5 18.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.8 9.5 5.1 4.7 7.7 12.8 10.4 11.0 8.2 9.7 16.1 0.2 0.0 2.4 1.3 0.0 0.3 0.1 1.8 0.0 0.2 0.3 0.8 0.1 1.5 1.9 0.0 0.0 0.1 0.1 0.1 1.9 0.4 292.5 16.8 0.6 0.6 0.0 0.0 0.5 0.4 0.1 0.5 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 312.9 6.8 0.5 0.0 1.0 0.0 2.2 0.0 1.0 5.6 0.3 0.0 5.3 0.0 0.1 0.0 1.8 37.8 1.2 0.0 0.5 0.4 241.3 5.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 C22orf42 ENSG00000205856 "Chromosome 22 open reading frame 42" Q6IC83 22 32149006-32159322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "brain: 12.5;testis: 10.6" "Group enriched" "Detected in some" 8 "Early spermatids: 95.7;Late spermatids: 31.3" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.8;prostate cancer: 1.0" "Group enriched" "Detected in many" 4 "hypothalamus: 8.9;midbrain: 4.5;pons: 4.5;thalamus: 12.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019531 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA019531: AB_1853016" "unprognostic (5.67e-2)" "unprognostic (6.13e-3)" "unprognostic (8.21e-3)" "unprognostic (7.06e-2)" "unprognostic (4.54e-2)" 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.8 4.5 0.0 0.4 0.0 0.9 0.0 4.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 10.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 0.1 0.4 0.0 8.9 0.8 4.5 4.5 0.4 12.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.7 0.2 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf15 MGC29762 ENSG00000273045 "Chromosome 2 open reading frame 15" Q8WU43 2 99141707-99151669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Proximal tubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 12.6;SCLC-21H: 12.2" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.61e-2)" "unprognostic (7.88e-2)" "unprognostic (4.22e-2)" "unprognostic (4.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.99e-2)" "unprognostic (5.37e-2)" "unprognostic (9.05e-3)" "unprognostic (1.62e-2)" "prognostic favorable (4.95e-4)" "unprognostic (2.54e-3)" "unprognostic (1.04e-1)" "prognostic favorable (1.23e-4)" "unprognostic (2.06e-1)" "unprognostic (4.22e-4)" "unprognostic (5.08e-1)" "unprognostic (2.97e-2)" 0.4 0.7 1.5 0.8 1.5 1.3 3.5 3.3 1.8 2.4 1.7 2.1 4.1 1.2 6.0 1.4 3.9 1.8 0.3 1.4 1.6 5.4 0.5 1.4 1.5 1.5 1.5 0.8 3.1 6.1 0.7 1.1 1.7 1.3 2.4 3.8 2.7 1.8 0.3 2.0 3.2 0.3 1.2 1.0 3.8 1.4 2.1 1.2 6.3 0.0 1.6 1.7 0.1 2.5 9.8 1.5 0.3 1.3 0.2 0.0 7.2 0.0 0.7 0.5 0.3 10.1 7.0 4.3 3.0 0.0 0.8 6.0 1.4 1.1 0.0 0.8 4.5 0.3 1.8 6.8 0.1 1.5 1.8 0.2 2.2 0.0 0.7 0.4 0.0 5.5 0.4 0.9 0.4 8.5 1.2 1.9 2.2 5.3 2.1 0.7 0.2 4.8 9.9 12.6 12.2 1.5 1.0 10.2 0.4 1.7 8.2 0.4 0.0 0.5 0.5 0.3 0.4 2.9 4.8 1.5 0.2 1.4 0.1 0.3 0.3 0.2 2.0 0.2 4.7 1.8 3.2 2.5 0.1 2.0 4.3 2.2 0.9 3.8 0.1 0.4 1.7 1.2 1.5 1.5 3.3 1.8 1.4 1.6 1.5 1.5 1.7 1.2 2.1 2.5 0.4 3.2 3.1 0.7 2.5 1.1 1.7 2.1 0.0 5.6 5.4 4.6 0.4 2.8 2.2 7.3 6.2 6.8 0.7 0.8 15.6 5.5 1.8 3.7 0.4 0.9 1.2 0.8 3.3 2.9 0.7 0.6 1.1 2.5 0.0 1.3 0.4 0.1 0.6 6.7 2.5 2.9 0.0 0.0 1.4 0.3 0.6 0.5 0.0 0.0 0.5 4.1 0.0 0.5 2.8 2.8 3.7 0.4 0.7 1.5 3.7 9.8 7.9 7.7 0.0 0.9 0.5 3.4 3.7 0.9 1.4 2.1 1.8 1.6 3.4 1.3 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C3orf70 ENSG00000187068 "Chromosome 3 open reading frame 70" A6NLC5 3 185076838-185153060 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;smooth muscle: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 76.8;Melanocytes: 39.2;Oligodendrocyte precursor cells: 143.2;Peritubular cells: 49.7" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.9;SCLC-21H: 16.4;SK-BR-3: 7.2;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041861 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA041861: AB_10804119" "unprognostic (1.45e-1)" "unprognostic (2.17e-3)" "unprognostic (3.92e-3)" "unprognostic (2.77e-1)" "unprognostic (2.31e-1)" "unprognostic (6.62e-4)" "unprognostic (5.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (5.98e-3)" "unprognostic (9.91e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.06e-1)" "unprognostic (8.48e-2)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" 2.2 0.8 10.8 2.4 8.5 0.1 1.3 7.2 8.8 3.1 0.0 11.1 2.6 9.8 2.6 5.1 5.2 2.2 2.0 9.9 9.1 0.5 0.3 0.9 0.4 15.9 11.5 2.3 0.2 2.1 0.8 1.3 10.1 5.1 4.1 3.9 3.0 8.4 0.5 1.5 3.6 14.8 13.6 2.1 2.8 4.0 12.0 0.3 1.1 0.6 0.6 4.9 2.0 14.0 0.0 0.1 1.9 0.0 0.0 0.0 0.1 2.6 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.6 2.2 0.1 0.5 0.0 0.3 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.8 2.0 0.1 0.0 3.9 0.0 0.0 0.4 16.4 0.1 0.8 7.2 0.4 0.0 0.4 1.8 0.6 0.0 1.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.9 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 10.8 8.5 7.2 8.8 9.9 9.1 15.9 11.5 10.1 13.6 12.0 14.0 5.1 0.0 0.0 45.7 1.0 4.1 0.3 0.0 0.6 76.8 1.0 0.5 1.6 0.0 0.0 0.0 0.0 10.8 0.0 9.1 0.0 0.1 1.2 0.1 2.3 4.4 1.2 0.0 13.8 0.2 0.6 3.8 0.0 0.1 0.0 3.9 6.8 0.0 4.0 3.3 19.4 8.8 0.0 0.6 0.7 1.5 3.4 0.3 39.2 6.5 0.6 2.5 0.0 143.2 10.1 0.5 2.2 49.7 0.1 0.3 4.6 0.1 0.0 7.3 6.6 1.3 15.4 6.8 12.5 0.2 1.8 0.8 0.2 1.8 6.3 0.3 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 C8orf88 ENSG00000253250 "Chromosome 8 open reading frame 88" P0DMB2 8 90958471-90985238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 91.6" "Cell type enhanced" "Detected in many" "Early spermatids: 612.7;Late spermatids: 138.4;Spermatocytes: 329.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 63.4" "Low region specificity" "Detected in all" HPA078486 Enhanced NA NA "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA078486: " "unprognostic (2.17e-1)" "unprognostic (7.00e-2)" "unprognostic (2.51e-2)" "unprognostic (2.95e-4)" "unprognostic (4.07e-2)" "unprognostic (1.19e-1)" "unprognostic (8.44e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.71e-2)" "unprognostic (9.89e-2)" "unprognostic (7.18e-2)" "unprognostic (6.04e-2)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (6.23e-6)" 8.0 3.8 2.2 4.2 2.9 11.0 6.7 2.4 2.7 10.6 4.9 32.9 2.1 21.4 13.1 8.7 11.9 7.1 38.2 2.2 3.2 4.9 1.0 4.7 1.7 3.0 2.6 13.3 1.3 0.4 4.1 3.5 3.0 13.9 5.7 1.6 2.4 23.5 1.4 7.1 6.5 30.8 3.2 3.0 13.3 91.6 2.7 13.0 10.9 1.8 1.4 19.0 7.8 4.3 0.1 2.4 13.4 1.2 15.4 13.4 0.2 14.6 22.8 19.8 29.7 0.1 3.8 0.3 1.3 14.9 20.6 0.1 0.2 1.1 36.7 0.0 38.6 41.7 11.5 0.0 63.4 0.0 1.3 14.1 0.3 22.3 37.0 28.9 2.1 13.6 25.0 23.9 30.3 0.0 39.7 14.9 3.3 0.0 0.7 0.0 26.1 0.1 16.3 0.1 11.4 19.8 0.6 0.0 19.6 15.1 0.0 1.9 8.5 22.8 38.0 0.3 15.5 33.3 33.4 21.2 22.6 0.0 10.5 0.0 0.0 0.0 0.9 0.0 1.2 1.1 0.8 1.0 0.2 0.9 0.7 1.4 0.0 3.8 0.0 3.2 0.6 0.4 2.2 2.9 2.4 2.7 2.2 3.2 3.0 2.6 3.0 3.2 2.7 4.3 6.4 0.0 1.1 1.3 2.9 18.9 9.3 1.0 19.4 0.0 0.5 8.6 12.4 2.8 0.1 3.7 0.0 0.2 0.8 0.0 5.9 1.1 612.7 0.3 9.0 4.7 0.0 55.6 3.1 0.0 0.9 13.7 0.0 0.2 2.5 4.9 5.0 0.0 0.6 0.0 6.4 0.0 0.0 0.8 3.8 138.4 19.0 1.7 10.6 1.9 0.6 0.9 0.0 2.0 4.0 3.6 0.0 21.8 3.0 6.6 0.0 1.4 0.1 0.2 19.7 8.2 21.1 329.5 30.7 6.9 26.6 0.0 2.8 2.0 0.0 1.2 C9orf152 bA470J20.2 ENSG00000188959 "Chromosome 9 open reading frame 152" Q5JTZ5 9 110190048-110208159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.6;salivary gland: 25.4;stomach 1: 32.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.4;Intestinal goblet cells: 139.7;Ionocytes: 40.7;Paneth cells: 40.0;Undifferentiated cells: 79.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 149.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050769 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "HPA050769: AB_2681230" "unprognostic (1.90e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "prognostic favorable (7.22e-5)" "unprognostic (2.28e-1)" "unprognostic (1.79e-3)" "unprognostic (6.86e-2)" "unprognostic (1.34e-1)" "unprognostic (4.84e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (5.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (4.57e-1)" "unprognostic (2.49e-1)" "unprognostic (1.06e-2)" 0.1 0.0 0.5 2.1 0.4 0.0 12.4 0.2 0.4 10.4 0.1 32.8 19.0 2.3 0.0 3.0 3.7 5.5 0.0 0.4 0.1 0.2 0.8 5.8 0.0 0.6 0.4 0.0 5.1 0.0 0.1 0.0 0.6 17.0 41.6 0.0 25.4 1.4 0.0 5.4 15.1 1.2 0.2 0.1 32.9 0.0 0.5 0.1 0.1 0.0 0.2 1.2 0.4 0.6 0.0 1.3 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 149.2 0.2 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.0 9.3 0.0 0.0 18.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.1 0.6 0.4 0.6 0.2 0.5 0.6 0.4 9.6 16.3 0.3 0.2 0.3 3.4 5.9 6.2 0.0 20.5 10.8 0.1 20.0 14.5 0.0 0.0 0.0 0.1 35.4 0.0 6.0 0.0 4.0 2.0 0.5 25.9 0.0 0.1 11.1 0.0 0.2 25.0 13.9 0.0 0.0 0.0 3.3 0.1 0.0 0.1 139.7 40.7 0.0 1.0 0.0 0.0 0.6 10.6 0.0 0.0 0.0 0.0 0.0 0.1 3.9 40.0 0.0 0.0 12.4 4.4 0.0 5.2 0.0 0.0 0.4 0.9 0.0 0.0 10.9 0.4 0.0 0.4 0.0 79.8 5.5 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Proximal enterocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 15.6;OE19: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 1.8 2.1 1.2 1.2 1.2 0.3 2.3 1.4 1.3 2.1 0.7 2.5 12.0 0.9 0.6 5.0 1.1 5.4 3.6 1.0 1.7 5.7 3.7 2.4 0.6 0.9 1.5 1.1 1.1 9.0 2.9 0.3 0.8 1.2 3.0 2.3 4.8 0.7 0.4 5.6 14.6 0.8 0.6 0.7 5.9 0.7 1.1 0.7 5.0 0.3 2.9 2.1 2.5 1.3 0.2 0.4 0.8 0.1 0.5 0.6 0.4 1.0 1.1 0.1 2.9 7.2 5.4 0.4 0.5 1.2 6.0 2.3 2.2 2.9 0.2 1.6 0.9 15.6 2.0 6.7 1.4 0.2 0.6 2.2 0.5 0.2 1.2 1.8 1.6 0.6 4.0 2.9 2.6 0.0 0.3 0.2 0.4 30.6 0.4 0.2 2.2 0.1 8.1 0.3 0.2 0.0 0.5 0.0 1.6 1.0 0.5 0.8 1.5 2.8 3.9 0.1 1.6 1.1 0.6 1.9 5.7 2.2 2.6 0.7 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.2 1.2 1.2 1.4 1.3 1.0 1.7 0.9 1.5 0.8 0.6 1.1 1.3 1.7 3.2 12.4 7.2 2.9 1.8 2.7 2.7 3.4 1.8 7.0 4.7 6.4 4.3 10.5 12.9 33.3 0.3 2.1 12.3 9.8 4.0 11.3 4.7 2.5 2.7 4.8 3.2 12.2 1.6 0.3 2.9 9.7 7.7 0.0 0.3 8.6 5.8 1.1 0.0 13.7 4.3 2.0 2.5 3.3 13.1 0.0 3.0 5.4 1.9 1.0 1.9 8.2 16.1 4.4 4.4 4.3 0.0 6.9 1.9 52.6 21.0 9.5 5.1 0.0 8.1 1.9 1.3 2.1 9.1 3.1 0.3 2.2 1.0 5.4 2.4 CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 5273.7" "Group enriched" "Detected in many" 8 "Erythroid cells: 221.3;Skeletal myocytes: 304.0" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEL: 47.3;RH-30: 78.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 53000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favorable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" 43.4 3.8 2.4 0.3 2.3 9.9 6.4 2.7 3.7 5.1 1.4 1.7 1.8 8.3 2.1 64.8 9.8 2.2 19.5 2.3 2.8 3.7 2.4 24.6 0.4 2.9 2.3 1.4 1.3 1.0 3.8 0.3 2.0 89.5 1.1 5.5 15.4 2.7 5273.7 5.2 4.4 19.1 2.5 0.8 4.1 2.9 2.5 1.4 3.0 1018.8 0.6 1.5 5.5 2.8 2.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.1 0.0 0.1 0.2 0.3 0.3 0.0 0.5 0.2 47.3 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 78.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 2.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.4 2.3 2.7 3.7 2.3 2.8 2.9 2.3 2.0 2.5 2.5 2.8 0.3 3.2 4.2 2.3 0.1 0.5 1.7 0.6 1.2 0.0 14.5 0.6 1.0 5.7 0.6 0.0 6.2 1.1 0.4 0.4 0.0 0.6 24.1 0.4 0.2 2.2 0.0 221.3 2.2 0.2 0.2 9.1 0.0 0.7 0.0 0.2 2.5 0.3 0.4 0.0 2.5 0.4 0.0 0.3 0.4 7.0 0.3 2.5 0.0 0.0 0.0 29.6 0.0 1.5 0.7 0.2 1.7 0.0 0.0 0.5 8.5 0.6 1.0 1.6 0.0 304.0 5.1 0.6 1.3 0.2 1.0 1.6 1.4 0.3 0.9 0.3 CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Enteroendocrine cells: 35.2;Gastric mucus-secreting cells: 40.2;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cell line enhanced" "Detected in some" "HEK 293: 10.1;JURKAT: 11.0;K-562: 20.3;NB-4: 12.3;OE19: 17.4" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" 1.6 0.9 5.2 0.3 5.8 0.5 4.6 18.3 5.6 4.3 2.0 1.3 1.0 1.9 10.2 0.2 1.5 0.3 4.3 4.4 5.3 5.3 0.0 0.9 0.4 4.7 4.9 0.2 1.9 40.1 8.5 6.2 5.0 1.5 2.0 2.3 3.7 0.2 1.2 0.3 1.0 0.5 3.1 0.8 4.4 4.1 5.1 1.3 0.3 2.3 0.3 0.6 0.3 4.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 10.1 4.5 0.0 0.0 3.6 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 20.3 0.2 0.0 0.0 3.3 12.3 0.2 17.4 0.0 0.0 0.0 0.2 0.4 0.8 5.1 0.0 0.0 1.1 0.0 2.0 4.5 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 76.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 5.2 5.8 18.3 5.6 4.4 5.3 4.7 4.9 5.0 3.1 5.1 4.0 22.0 0.0 4.8 92.7 1.6 1.0 0.4 4.1 0.0 8.2 15.6 10.3 4.7 0.0 5.7 3.7 0.0 8.3 10.9 2.0 3.9 8.1 9.9 9.8 2.4 16.7 35.2 13.5 4.7 6.0 0.3 4.0 40.2 26.2 0.0 1.1 0.0 0.0 9.9 0.0 25.6 25.0 6.1 1.9 1.1 4.9 1.5 1.1 7.2 18.7 0.0 2.6 1.0 129.7 0.4 1.6 3.5 1.5 14.0 2.1 0.3 0.0 1.2 1.0 0.0 0.8 2.3 3.8 5.5 0.2 0.4 1.4 0.7 3.1 3.3 1.5 CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970786-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 20.7;heart muscle: 27.1;intestine: 29.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 606.7;Horizontal cells: 301.2;Inhibitory neurons: 476.2;Oligodendrocyte precursor cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "HDLM-2: 87.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" 3.0 0.9 4.5 1.4 0.9 0.0 1.9 0.0 3.0 5.6 0.0 29.9 0.7 20.7 0.5 2.1 4.2 2.3 27.1 2.0 0.5 2.5 0.4 4.6 0.3 0.0 0.5 1.9 0.9 0.1 5.2 2.1 0.0 6.5 1.3 1.7 1.0 3.3 0.9 1.3 5.0 10.2 0.0 3.0 5.4 2.5 1.8 0.2 1.3 0.8 0.3 12.3 3.4 0.1 0.0 0.0 0.1 0.0 3.3 2.0 0.2 3.4 4.1 2.2 1.5 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.8 87.0 0.8 0.1 0.0 0.0 2.1 0.0 0.1 5.1 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.4 0.6 5.2 0.0 0.1 0.2 0.0 4.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.5 0.9 0.0 3.0 2.0 0.5 0.0 0.5 0.0 0.0 1.8 0.1 2.2 0.0 0.0 96.6 0.2 0.6 1.0 0.0 0.0 20.7 0.8 8.3 48.8 0.0 0.0 0.0 2.1 0.2 1.3 0.6 0.0 0.1 35.6 5.1 14.6 5.2 36.6 0.8 606.7 0.0 0.4 4.2 2.0 0.9 0.0 2.7 2.2 0.1 0.3 301.2 476.2 0.6 0.0 0.0 1.1 90.3 0.9 0.2 0.0 72.1 0.0 6.0 1.0 194.5 21.7 0.4 1.2 4.1 0.2 1.2 0.0 0.1 0.0 1.3 13.1 1.6 26.7 3.4 5.8 0.1 0.1 0.1 1.1 0.2 0.5 3.1 CACNA1H Cav3.2 ENSG00000196557 "Calcium voltage-gated channel subunit alpha1 H" O95180 16 1153106-1221771 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 107.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8;Late spermatids: 15.5;Peritubular cells: 25.9;Sertoli cells: 26.3;Smooth muscle cells: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 17.9;AN3-CA: 25.4;MCF7: 48.3;OE19: 16.0;T-47d: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039125 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Vesicles" "HPA039125: AB_10795578" "unprognostic (1.66e-3)" "unprognostic (2.10e-1)" "unprognostic (4.07e-2)" "unprognostic (1.21e-3)" "unprognostic (1.37e-2)" "unprognostic (2.15e-1)" "unprognostic (4.39e-2)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" "prognostic favorable (3.12e-5)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.93e-2)" "unprognostic (4.65e-2)" "unprognostic (1.70e-2)" "unprognostic (5.55e-2)" 13.6 28.0 13.6 5.2 24.5 0.1 7.6 2.1 12.1 26.3 0.0 107.7 6.4 57.3 2.6 7.1 37.8 10.3 9.3 11.0 8.1 14.1 13.4 11.8 0.7 3.0 3.8 80.1 4.6 3.6 45.9 2.1 2.9 28.0 2.4 1.8 1.9 27.5 6.2 19.4 22.3 15.6 3.7 0.7 27.5 19.4 13.5 0.5 11.0 3.0 0.2 57.0 17.1 0.2 0.0 17.9 3.0 25.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 10.4 0.1 0.0 11.0 3.0 0.0 4.5 0.3 0.0 0.0 0.0 0.0 0.0 3.0 4.9 0.0 0.0 48.3 0.0 0.0 9.4 16.0 3.6 0.0 0.0 0.2 4.7 0.0 0.0 0.0 0.0 0.0 0.9 1.0 13.9 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 24.5 2.1 12.1 11.0 8.1 3.0 3.8 2.9 3.7 13.5 0.2 1.3 0.0 0.0 1.0 0.0 1.5 0.1 0.0 0.0 22.8 0.3 0.1 2.7 4.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.7 7.2 0.2 5.3 2.2 10.8 0.0 2.6 0.0 0.1 1.3 0.5 0.2 4.5 0.0 0.4 7.8 0.1 0.0 0.7 1.0 2.0 0.0 0.3 15.5 8.4 0.2 0.0 0.0 0.0 0.8 0.0 0.5 0.1 0.4 0.4 25.9 0.0 7.2 0.0 0.7 0.0 1.5 26.3 0.4 22.4 3.4 5.1 0.0 3.4 0.0 0.2 0.3 0.1 1.3 CACNA2D3 HSA272268 ENSG00000157445 "Calcium voltage-gated channel auxiliary subunit alpha2delta 3" Q8IZS8 3 54122547-55074557 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.8;skeletal muscle: 9.9;tongue: 10.7" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 828.3;Inhibitory neurons: 456.4;Oligodendrocyte precursor cells: 317.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.1;HAP1: 1.9;HeLa: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030849 Uncertain Nucleoplasm NA NA 69000 "Cluster 47: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA030849: " "unprognostic (6.92e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-5)" "unprognostic (5.53e-3)" "unprognostic (2.64e-3)" "unprognostic (3.24e-1)" "unprognostic (1.17e-2)" "unprognostic (5.84e-3)" "unprognostic (7.22e-3)" "unprognostic (1.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.00e-1)" "unprognostic (1.47e-3)" "unprognostic (2.19e-1)" "unprognostic (3.62e-2)" "unprognostic (6.95e-2)" 0.2 4.1 8.8 0.1 11.6 0.0 0.2 0.0 15.8 0.3 0.0 0.7 0.1 0.1 1.3 0.5 0.4 0.2 2.6 9.4 8.4 1.3 0.0 0.5 0.5 2.1 10.2 2.5 0.0 0.3 0.8 0.5 1.3 1.0 0.3 2.9 0.4 1.5 9.9 0.1 0.3 0.6 0.0 0.2 0.4 1.4 3.5 0.1 0.4 10.7 0.5 0.1 0.4 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 9.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 11.6 0.0 15.8 9.4 8.4 2.1 10.2 1.3 0.0 3.5 9.9 0.5 0.0 0.0 160.9 0.6 0.3 0.4 0.2 7.4 10.8 0.2 0.5 30.2 0.0 0.7 0.0 8.4 9.9 5.5 0.1 7.9 0.0 83.4 0.9 0.8 0.6 0.0 1.3 828.3 0.6 3.2 3.4 1.5 1.8 0.0 1.1 0.4 0.0 5.9 0.0 456.4 0.0 2.0 8.9 2.7 56.1 2.8 11.0 0.0 97.4 22.2 5.0 0.0 317.7 11.3 1.2 0.0 1.5 0.1 0.4 0.0 0.2 0.8 1.4 6.6 1.7 1.9 5.7 2.9 3.4 0.1 68.0 0.7 0.8 0.0 0.4 CACNB2 "CACNLB2, MYSB" ENSG00000165995 "Calcium voltage-gated channel auxiliary subunit beta 2" Q08289 10 18140424-18543557 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 863.5;Excitatory neurons: 545.7;Inhibitory neurons: 357.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HAP1: 6.4;HSkMC: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035326 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035326: AB_10669903" "unprognostic (3.03e-3)" "unprognostic (3.04e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (4.58e-3)" "unprognostic (4.67e-4)" "unprognostic (8.03e-2)" "unprognostic (3.76e-2)" "unprognostic (8.10e-2)" "unprognostic (1.70e-1)" "unprognostic (7.78e-4)" "unprognostic (1.40e-1)" "prognostic favorable (3.56e-5)" "unprognostic (3.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.03e-1)" "unprognostic (8.16e-2)" 2.8 9.4 1.3 2.1 3.9 1.3 3.8 5.4 12.9 7.4 0.1 17.6 1.1 12.8 2.7 5.0 10.1 2.2 17.8 5.4 7.4 3.2 10.7 3.9 0.9 0.0 0.1 13.6 7.5 0.6 19.3 0.5 0.0 8.5 3.2 35.1 3.9 8.8 1.1 4.2 11.4 5.3 0.0 1.5 7.7 2.1 2.2 0.7 2.5 0.7 0.2 16.8 4.6 1.5 0.2 1.0 0.7 0.5 0.3 0.3 0.5 0.3 0.0 0.0 0.3 0.4 0.5 0.9 0.2 0.2 0.3 0.7 6.4 0.0 0.0 0.3 2.4 0.8 1.7 1.5 1.6 0.5 1.5 8.1 0.0 0.0 0.0 0.3 0.0 1.4 0.9 1.6 0.0 0.7 0.8 1.0 2.4 0.0 0.0 0.7 0.7 0.8 0.0 0.8 2.9 0.8 0.1 0.0 0.4 0.8 0.1 0.9 0.0 0.6 1.5 0.3 0.6 1.6 1.8 1.7 0.2 1.2 0.3 1.4 0.1 0.2 0.2 0.2 0.4 0.4 0.3 0.1 0.0 0.5 0.5 0.8 0.1 0.3 0.2 0.2 1.1 0.0 1.3 3.9 5.4 12.9 5.4 7.4 0.0 0.1 0.0 0.0 2.2 1.5 2.1 0.0 0.6 863.5 0.1 3.3 1.3 0.0 1.8 31.9 1.1 1.3 22.4 0.0 0.0 0.0 108.4 0.4 0.7 2.8 1.9 0.4 0.9 1.1 13.9 1.5 37.1 0.8 545.7 0.2 0.0 3.0 0.0 2.6 0.0 3.8 0.0 0.9 0.1 8.4 357.8 9.4 0.0 0.0 1.1 0.8 0.9 0.5 1.8 96.5 0.0 15.9 0.0 95.5 13.7 0.2 2.4 4.5 0.3 2.1 5.9 0.8 0.0 75.7 6.6 2.6 14.2 0.1 0.1 0.0 4.1 0.3 1.0 5.3 5.7 1.3 CACNG4 "MGC11138, MGC24983" ENSG00000075461 "Calcium voltage-gated channel auxiliary subunit gamma 4" Q9UBN1 17 66964707-67033398 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 35.1;prostate: 11.7" "Cell type enriched" "Detected in some" 6 "Oligodendrocyte precursor cells: 145.3" "Group enriched" "Detected in many" 5 "breast cancer: 30.3;glioma: 35.8;ovarian cancer: 14.8;prostate cancer: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 387.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 118.1" "HPA005803, HPA065370" Enhanced Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA005803: AB_2667439, HPA065370: AB_2685480" "unprognostic (1.27e-1)" "unprognostic (3.16e-1)" "unprognostic (8.87e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-2)" "unprognostic (8.64e-3)" "unprognostic (2.91e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-2)" "unprognostic (3.85e-2)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (2.38e-10)" "unprognostic (8.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.71e-2)" "unprognostic (4.28e-1)" 0.5 0.8 26.5 0.1 35.1 0.0 5.3 6.9 26.8 0.4 4.2 0.8 0.2 0.5 0.1 0.2 4.2 0.4 0.2 14.5 17.9 0.2 0.0 5.7 0.0 11.7 16.7 0.1 0.4 1.2 0.3 0.7 15.0 11.7 0.1 0.7 1.7 1.3 0.1 0.5 0.1 1.1 14.3 0.0 1.5 0.2 29.6 0.0 0.1 0.0 0.0 0.4 0.7 9.5 6.4 4.1 15.6 0.0 0.0 0.0 4.4 0.0 0.0 1.4 0.0 4.6 0.2 0.0 0.2 0.0 41.2 64.1 0.1 0.0 0.0 0.0 0.3 0.0 1.8 3.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 34.5 0.1 0.3 15.7 7.3 0.0 0.0 0.4 8.7 0.0 11.1 15.8 387.4 3.6 10.4 0.0 38.1 38.5 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 35.1 6.9 26.8 14.5 17.9 11.7 16.7 15.0 14.3 29.6 9.5 0.0 3.2 1.3 0.0 0.0 0.0 1.1 0.3 0.0 0.2 6.4 3.4 1.3 0.0 1.4 0.0 0.0 0.3 0.1 0.6 0.0 0.1 2.6 1.0 0.2 0.1 7.7 0.0 1.8 0.2 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.7 0.0 3.4 0.0 145.3 0.3 0.7 0.2 0.0 0.0 2.6 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.7 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CALM1 "CALML2, CAMI, DD132, PHKD" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408268 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018558, HPA044999" Supported Supported Cytosol NA NA 75000000 "Cluster 44: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB018558: AB_2069454, HPA044999: AB_2679177" "unprognostic (5.35e-3)" "unprognostic (3.96e-1)" "unprognostic (4.99e-3)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.52e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" "prognostic favorable (5.62e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.49e-4)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.38e-5)" 264.2 143.5 429.9 152.3 537.5 349.1 123.1 442.8 839.7 134.2 259.8 332.9 289.6 105.1 209.7 304.6 251.4 153.8 287.0 635.9 371.6 326.3 210.9 209.1 165.7 466.2 374.6 104.4 121.7 225.5 143.9 207.4 447.5 169.5 312.2 241.6 188.0 215.3 588.9 104.0 279.2 227.2 328.7 166.6 202.2 123.6 443.5 146.5 118.0 185.6 210.5 191.6 125.2 527.2 189.3 256.3 308.0 115.7 332.2 286.5 256.9 347.4 295.3 260.0 283.2 278.1 320.9 200.8 171.1 413.0 123.4 309.4 194.6 490.1 431.0 398.3 119.7 212.4 211.0 264.1 185.9 327.6 167.2 188.0 232.7 261.6 93.1 173.6 592.9 140.3 101.3 270.0 353.9 653.7 112.4 316.2 178.4 521.1 351.6 216.9 264.9 134.4 215.3 574.5 621.2 259.1 292.3 507.7 195.5 254.0 335.6 112.0 363.1 212.9 137.7 224.8 289.0 149.5 371.0 222.2 335.9 267.6 301.5 1289.6 356.8 826.7 1005.3 420.4 1230.3 496.8 1039.1 1079.6 483.1 400.2 745.7 882.7 513.3 1036.9 647.3 453.3 1168.3 1477.9 429.9 537.5 442.8 839.7 635.9 371.6 466.2 374.6 447.5 328.7 443.5 527.2 1812.3 387.8 374.4 119.8 573.2 567.1 572.2 604.2 543.5 1729.1 343.7 514.8 867.5 346.0 523.1 399.1 123.0 427.7 1471.8 828.8 459.7 550.8 154.9 1026.1 249.0 996.0 599.8 143.5 367.6 444.7 984.2 521.4 317.0 377.6 490.3 148.5 652.5 333.7 795.1 604.0 258.9 513.9 730.4 286.5 837.4 101.5 210.6 639.9 627.9 131.2 856.3 1061.8 1100.9 108.0 188.9 534.2 615.8 500.2 591.8 287.7 1637.2 1430.5 1618.4 321.1 315.5 387.5 901.6 128.8 199.8 553.8 580.4 1147.6 1139.3 247.8 666.6 458.5 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.3" "Cell type enhanced" "Detected in many" "Astrocytes: 410.7;Cytotrophoblasts: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 133.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 154.8;SK-BR-3: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 22.0 14.0 86.1 17.0 92.6 34.5 15.2 79.9 137.8 24.1 44.1 101.1 34.2 45.2 14.5 34.7 30.6 17.8 11.8 91.3 79.0 19.3 14.5 18.8 16.2 96.1 96.5 12.7 10.3 12.3 14.1 27.3 94.1 31.1 26.1 42.4 22.9 49.6 154.3 17.3 41.5 43.9 91.4 24.9 30.4 6.5 102.5 15.7 13.6 84.8 14.9 58.4 25.8 91.9 35.7 24.6 22.5 43.9 16.7 26.1 26.3 25.8 41.0 31.9 26.1 39.8 37.2 27.4 25.7 32.4 12.4 54.9 17.5 20.5 25.3 24.0 22.2 18.2 20.4 17.8 8.1 24.7 29.1 14.4 17.7 32.5 22.1 50.4 28.3 32.5 19.5 37.9 19.0 25.2 41.7 37.5 16.5 21.3 154.8 36.5 25.3 13.7 17.2 51.5 11.5 28.4 15.0 177.4 11.9 16.5 33.2 15.0 36.7 24.9 40.0 13.4 33.3 11.9 14.9 24.8 26.5 69.2 8.8 31.0 17.9 133.9 23.1 7.9 28.5 13.9 26.3 25.0 23.0 12.7 24.5 24.1 115.8 34.0 15.1 7.9 27.7 17.5 86.1 92.6 79.9 137.8 91.3 79.0 96.1 96.5 94.1 91.4 102.5 91.9 19.3 16.0 11.7 410.7 22.2 9.4 8.7 9.2 14.2 63.3 14.8 16.3 6.7 12.8 15.5 7.3 100.1 163.6 21.3 46.2 13.7 13.3 2.0 6.3 6.4 20.2 23.9 13.3 107.9 19.6 45.2 12.0 14.8 7.5 16.5 20.2 16.4 9.6 27.2 26.9 89.7 24.8 10.2 18.9 16.3 3.1 12.8 15.8 12.4 43.1 18.3 17.7 26.8 61.9 16.9 22.0 65.5 18.8 13.6 8.2 77.1 26.9 10.4 77.0 46.0 11.2 50.8 0.8 13.5 26.5 12.6 81.1 30.3 5.2 32.1 13.7 CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 40.0;Gastric mucus-secreting cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.7;Hep G2: 15.6;MCF7: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043830, HPA062149" Enhanced Approved Nucleoplasm,Centrosome NA NA "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Centrosome" "HPA043830: AB_10795879, HPA062149: AB_2684698" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" 0.4 3.3 3.2 0.8 4.4 0.0 5.3 2.5 9.0 7.7 0.1 10.3 14.9 0.5 2.3 24.8 3.1 1.6 0.4 4.2 0.7 12.0 24.3 4.6 0.2 2.5 0.0 0.5 20.6 2.7 8.2 0.4 0.4 10.2 2.4 3.2 18.1 4.5 0.2 62.7 11.5 0.1 0.0 0.6 15.5 13.0 0.2 0.5 11.1 0.0 1.1 3.6 13.4 2.4 11.2 1.8 0.3 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 26.7 5.8 3.1 4.5 0.0 1.2 9.7 4.3 2.8 0.0 2.0 10.1 0.0 0.5 15.6 0.0 0.0 4.4 0.0 5.5 0.0 0.4 0.4 0.0 4.5 0.9 0.0 0.0 13.0 0.2 0.2 6.6 8.4 4.7 0.7 0.0 3.7 1.9 6.0 8.2 8.7 1.3 12.5 0.0 1.6 10.4 1.7 0.0 0.0 2.0 0.0 0.4 5.0 1.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 2.5 9.0 4.2 0.7 2.5 0.0 0.4 0.0 0.2 2.4 0.2 9.6 19.2 3.3 1.1 9.8 2.7 2.4 3.4 22.7 19.3 12.1 1.5 20.0 5.3 9.2 0.0 0.5 0.2 40.0 3.9 5.7 4.4 9.6 1.4 1.5 13.1 0.0 9.1 11.8 0.7 0.2 38.7 13.5 5.7 8.6 0.4 24.8 0.2 10.1 10.1 22.4 0.0 1.9 1.2 2.9 1.5 1.0 0.0 1.9 0.0 1.5 0.0 4.5 0.6 13.1 28.4 0.0 0.6 6.2 29.2 15.6 2.9 13.4 0.0 0.0 1.1 0.4 2.8 9.8 18.9 0.5 0.9 1.5 18.4 8.0 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 6 "Gastric mucus-secreting cells: 910.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 125.9;RT4: 76.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.3 0.2 4.7 6.3 1.0 0.1 14.9 0.1 1.7 1.1 2.3 23.6 8.0 0.1 11.1 0.6 1.3 14.3 0.0 2.3 3.6 1.7 0.3 21.3 0.1 2.7 1.5 0.2 2.9 0.0 0.1 0.3 1.1 2.9 33.0 0.3 8.5 1.4 0.8 2.3 4.6 1.1 2.0 0.3 291.1 0.6 1.8 0.0 0.2 0.0 0.3 12.3 0.7 2.5 1.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.8 0.0 4.6 0.0 0.1 0.0 0.2 8.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.2 125.9 3.8 0.1 0.0 0.0 1.3 76.8 1.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 4.7 1.0 0.1 1.7 2.3 3.6 2.7 1.5 1.1 2.0 1.8 2.5 0.4 28.9 131.7 1.6 1.8 0.1 6.5 1.9 0.0 0.0 19.9 7.9 2.6 10.0 55.9 25.8 0.0 0.2 0.2 90.9 0.0 3.8 2.3 2.0 0.3 0.7 3.0 0.0 0.6 21.6 0.0 0.3 910.8 2.1 10.8 5.2 0.0 0.3 0.6 0.0 0.1 61.9 4.1 0.0 0.8 6.7 1.8 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 36.1 42.6 3.4 3.5 4.0 2.1 1.5 15.0 0.0 0.0 0.3 0.8 0.4 1.0 0.0 0.0 0.1 1.4 2.9 21.2 31.2 CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 85.7;skin 1: 102.4" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 87.8;Basal squamous epithelial cells: 117.3;Squamous epithelial cells: 108.6;Suprabasal keratinocytes: 149.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.3;urothelial cancer: 21.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Cell line enriched" "Detected in some" 10 "hTCEpi: 223.0" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA059749: AB_2732639, HPA076768: AB_2732322" "unprognostic (3.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.77e-3)" "unprognostic (4.14e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (7.21e-2)" "unprognostic (3.38e-2)" "unprognostic (3.62e-1)" "unprognostic (2.42e-2)" "unprognostic (4.48e-1)" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" 0.4 0.0 0.4 0.1 0.7 0.6 6.6 0.9 0.5 14.3 0.4 0.0 0.0 0.1 0.2 85.7 0.8 0.0 0.1 0.5 0.6 0.0 0.1 0.2 0.0 1.5 0.9 0.1 0.1 0.0 0.1 0.3 1.6 4.2 0.0 0.1 16.8 0.1 0.7 102.4 0.1 0.0 1.1 0.1 0.1 0.0 1.1 0.2 0.3 0.0 18.6 18.1 33.5 1.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 23.0 0.0 1.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.7 0.8 0.0 223.0 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 1.1 0.1 7.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 1.2 0.0 0.1 3.8 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.7 0.9 0.5 0.5 0.6 1.5 0.9 1.6 1.1 1.1 1.5 0.6 0.0 0.5 0.0 0.0 87.8 10.0 13.7 117.3 0.0 0.2 0.3 0.0 0.0 11.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.8 7.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.5 0.7 0.0 0.0 108.6 149.3 2.3 0.2 0.1 0.0 15.4 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80209331 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;skin 1: 14.4;vagina: 7.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 8.2;Microglial cells: 6.5;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 5.2;SK-BR-3: 6.9;T-47d: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Aggresome,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Cytosol Aggresome "HPA023388: AB_1846020" "unprognostic (9.79e-3)" "unprognostic (3.86e-2)" "unprognostic (4.26e-1)" "unprognostic (1.05e-5)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.92e-4)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (3.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.62e-8)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" 0.3 1.1 0.3 0.6 0.3 0.2 2.6 0.1 0.4 4.9 0.1 0.4 1.1 0.3 0.3 13.5 0.6 0.4 0.2 0.3 0.3 0.6 0.3 0.6 0.6 0.5 0.3 0.4 0.4 0.0 0.5 0.2 0.4 2.5 0.0 0.3 3.3 0.0 0.4 14.4 0.8 0.0 0.1 1.5 0.5 1.2 0.4 0.0 0.5 0.0 1.6 1.0 7.3 0.4 1.7 0.4 0.3 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.8 0.6 0.0 1.9 0.2 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 5.2 0.0 0.0 0.1 1.0 0.1 0.0 1.1 0.4 0.0 1.6 0.4 0.1 0.0 6.9 0.8 0.4 10.4 0.0 0.4 0.1 0.3 0.3 0.0 2.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.4 0.3 0.3 0.5 0.3 0.4 0.1 0.4 0.4 0.3 0.0 1.1 1.6 0.1 1.8 4.0 2.1 0.0 0.6 4.5 2.2 0.9 2.8 2.0 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.7 1.3 0.2 0.9 0.0 0.0 0.9 2.2 0.4 0.5 0.0 1.5 0.0 0.4 0.7 0.0 0.8 0.0 0.8 0.1 0.0 8.2 0.8 0.1 0.3 0.6 1.8 6.5 0.1 1.4 0.0 1.0 11.6 1.8 0.1 0.4 0.1 3.2 0.9 0.3 3.6 0.8 0.0 0.2 0.3 1.3 0.4 5.0 3.0 1.5 0.3 0.7 0.5 3.6 CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 14.1;Hofbauer cells: 21.2;Horizontal cells: 15.2;Kupffer cells: 18.8;Langerhans cells: 12.9;Macrophages: 22.3;monocytes: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 22.5;HMC-1: 69.7;NB-4: 50.0;THP-1: 63.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" 1.2 1.3 0.5 4.7 0.5 13.0 1.2 2.5 1.0 2.0 0.3 1.0 1.3 0.8 0.4 1.0 1.8 1.0 0.5 0.5 0.7 1.0 0.9 3.4 1.2 1.9 0.9 0.3 0.5 0.1 0.8 0.9 1.3 1.8 0.4 0.2 1.1 1.0 0.2 2.7 1.8 1.1 1.4 9.9 0.6 0.4 1.1 0.4 0.4 0.0 1.5 1.2 1.1 1.7 0.1 0.0 0.3 0.0 0.0 0.0 4.6 9.5 0.3 0.2 0.0 0.7 0.0 0.0 0.1 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.5 0.1 6.8 4.9 12.2 69.7 0.0 0.1 0.2 0.2 0.0 0.1 0.0 5.3 0.0 0.0 0.2 0.0 50.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 12.3 0.0 16.0 0.1 0.0 4.1 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 16.0 0.0 6.9 34.5 11.5 0.0 57.6 0.9 0.0 0.0 0.0 26.0 0.0 0.0 0.0 2.3 0.7 50.5 0.1 0.5 14.1 0.5 0.5 2.5 1.0 0.5 0.7 1.9 0.9 1.3 1.4 1.1 1.7 0.8 0.0 4.6 4.6 1.1 1.8 0.6 0.3 3.4 0.2 4.2 4.3 2.6 0.0 4.9 3.7 0.0 0.4 2.2 0.4 1.9 0.1 1.0 1.2 14.1 1.1 0.0 2.5 2.1 0.0 0.4 2.1 1.5 1.4 10.8 0.4 0.7 0.1 21.2 15.2 1.1 0.0 0.0 18.8 12.9 6.9 0.3 22.3 1.8 6.5 16.3 4.6 3.1 0.0 0.2 0.0 0.1 0.0 1.4 0.1 0.0 0.3 0.6 0.9 0.0 0.3 1.5 1.0 1.5 0.9 1.7 0.4 1.4 0.2 0.2 0.6 CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;intestine: 13.4;lymphoid tissue: 21.6" "Group enriched" "Detected in some" 4 "B-cells: 3.6;dendritic cells: 3.7;T-cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 64.2;JURKAT: 47.3;MOLT-4: 64.6;REH: 105.6;RPMI-8226: 58.4;U-698: 107.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA041402: AB_10795591" "unprognostic (1.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.35e-2)" "unprognostic (6.37e-2)" "unprognostic (5.47e-3)" "unprognostic (4.27e-4)" "unprognostic (1.38e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (5.14e-10)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-2)" 0.9 0.5 5.9 12.5 6.3 5.9 0.5 4.5 11.4 0.4 2.4 2.0 1.8 0.3 0.1 0.9 0.5 1.2 0.3 9.8 5.1 0.9 0.8 1.7 21.6 5.6 4.0 0.2 0.4 0.1 4.5 0.2 5.4 0.8 0.7 0.3 1.4 0.1 0.0 0.4 13.4 0.2 3.4 19.9 1.9 0.9 4.9 20.9 1.2 0.0 10.9 1.5 0.7 6.8 0.2 0.1 0.1 0.3 0.0 0.1 18.1 0.6 0.0 0.5 0.0 9.6 0.6 64.2 1.1 0.0 0.1 0.1 6.0 0.0 0.0 14.3 7.5 3.8 0.3 1.2 0.5 7.1 0.6 0.1 0.0 0.0 0.1 0.1 0.0 47.3 0.9 1.0 0.0 1.1 64.6 32.2 10.7 0.3 0.3 105.6 0.1 58.4 0.0 0.0 15.9 1.7 0.1 0.2 0.5 1.5 0.4 1.9 0.2 0.9 2.0 0.1 0.4 17.6 33.4 107.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.7 0.1 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.3 0.7 0.1 5.9 6.3 4.5 11.4 9.8 5.1 5.6 4.0 5.4 3.4 4.9 6.8 0.4 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 118.6;brain: 183.6" "Group enriched" "Detected in some" 5 "Bipolar cells: 47.4;Early spermatids: 25.4;Prostatic glandular cells: 39.5;Spermatocytes: 55.7" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 209.0" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.14e-1)" 2.4 118.6 85.6 4.4 10.1 0.0 9.3 2.6 48.9 0.0 3.9 16.8 5.5 2.8 0.7 0.3 0.4 0.2 0.1 28.0 134.0 0.3 0.0 0.1 0.0 69.8 111.9 0.1 0.5 0.0 5.2 0.0 183.6 8.6 4.5 21.4 0.1 0.0 0.0 0.1 3.4 15.1 24.5 0.0 14.6 7.1 102.4 0.2 5.4 0.0 0.0 0.0 0.3 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.6 10.1 2.6 48.9 28.0 134.0 69.8 111.9 183.6 24.5 102.4 9.8 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 47.4 0.2 0.3 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 25.4 1.6 0.1 1.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 39.5 0.0 0.0 0.0 8.1 0.0 0.0 0.1 55.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.5;Endothelial cells: 42.2;Hepatic stellate cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA071906: AB_2732191, HPA075184: AB_2732281" "unprognostic (1.60e-1)" "unprognostic (4.54e-2)" "unprognostic (9.12e-3)" "unprognostic (5.27e-3)" "unprognostic (9.32e-2)" "unprognostic (5.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-2)" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.47e-5)" "unprognostic (1.82e-2)" "prognostic favorable (4.83e-8)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.95e-2)" 33.8 22.7 19.4 4.9 22.6 0.4 30.0 19.7 18.6 15.1 4.6 16.5 9.0 21.0 2.7 10.8 21.7 11.2 28.2 16.7 17.2 26.9 11.3 42.3 2.9 22.6 21.7 12.0 10.8 9.4 13.6 11.8 18.7 14.9 2.9 4.8 11.5 8.7 15.3 12.7 11.4 10.4 18.1 30.8 15.0 5.6 20.0 2.9 22.6 9.9 1.5 16.0 14.3 23.1 13.3 17.2 10.2 14.4 6.6 4.1 11.2 6.6 8.7 15.8 10.2 19.0 5.6 0.5 7.4 7.7 10.5 12.0 8.2 7.7 3.9 4.7 10.8 9.4 17.2 7.5 7.7 0.5 12.6 3.5 10.4 8.2 5.9 5.3 16.2 13.3 6.9 1.6 5.0 31.1 24.3 0.7 7.5 10.3 17.5 12.8 21.8 2.1 10.2 13.4 10.4 10.2 13.9 18.7 11.0 8.7 13.7 4.0 13.9 16.1 14.6 7.9 8.7 1.2 5.9 1.5 5.6 0.3 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 22.6 19.7 18.6 16.7 17.2 22.6 21.7 18.7 18.1 20.0 23.1 75.5 3.2 2.2 11.1 1.3 8.0 2.5 3.5 6.8 6.5 5.8 5.0 11.4 2.8 1.8 9.2 10.4 2.2 0.6 11.7 3.9 5.1 0.5 2.8 4.4 42.2 7.7 8.0 1.3 5.3 1.9 6.0 8.2 5.7 0.0 14.9 56.7 6.8 2.7 3.3 1.7 4.3 8.2 4.1 3.1 2.3 8.1 1.2 1.8 7.5 2.0 28.2 0.0 15.1 8.3 6.0 6.0 11.3 1.6 2.5 8.4 3.1 1.4 6.8 0.0 5.5 6.4 2.7 4.4 4.5 7.0 2.2 0.5 5.7 4.6 2.2 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 571.0;eosinophil: 408.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 571.0" "Cell line enhanced" "Detected in all" "Karpas-707: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 94000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 16.3 12.1 11.3 26.6 10.9 32.8 16.3 18.6 11.4 12.7 10.0 34.2 54.1 12.7 12.9 27.7 9.2 19.9 14.7 10.8 12.2 8.5 22.0 12.8 43.4 10.8 11.5 8.9 13.4 9.0 8.8 26.1 11.4 11.3 33.9 12.7 13.2 10.6 13.9 16.1 41.8 15.3 11.6 23.0 31.2 9.3 11.3 39.0 10.6 14.1 41.9 24.4 12.0 13.0 31.0 16.7 65.3 31.6 39.4 52.2 37.6 90.2 67.7 61.9 35.4 30.7 25.2 42.4 13.9 44.1 29.2 25.5 52.1 32.1 69.7 109.9 28.7 68.2 12.9 71.4 47.3 55.9 62.3 71.7 38.3 39.3 31.4 44.4 77.6 43.1 57.2 259.8 64.5 13.2 89.1 51.8 65.1 33.7 20.9 63.6 30.8 41.2 52.9 49.3 37.1 40.5 39.1 35.1 52.1 64.3 19.2 35.9 54.1 28.2 25.9 21.1 42.4 118.9 121.6 29.2 34.2 38.5 40.9 571.0 26.1 408.6 32.1 43.3 34.4 26.0 29.5 46.3 33.3 18.6 22.2 32.8 35.6 62.0 71.0 26.5 64.1 47.5 11.3 10.9 18.6 11.4 10.8 12.2 10.8 11.5 11.4 11.6 11.3 13.0 28.6 19.2 15.8 26.4 32.3 48.7 22.2 34.1 35.9 18.6 21.7 17.0 17.5 5.7 36.3 12.9 0.0 46.9 54.8 37.4 13.7 18.4 9.6 24.9 17.1 26.6 18.0 62.3 9.6 23.7 33.6 19.5 24.5 24.9 17.7 24.8 21.0 15.3 23.9 13.5 12.6 37.6 44.7 27.0 17.4 4.0 7.5 33.3 30.2 13.1 41.5 15.4 37.0 11.1 18.4 25.0 18.8 7.5 118.6 20.1 26.6 8.4 30.4 11.3 13.1 19.0 20.8 7.9 16.4 34.6 28.6 51.4 43.8 23.1 24.4 36.7 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CATIP "C2orf62, MGC50811" ENSG00000158428 "Ciliogenesis associated TTC17 interacting protein" Q7Z7H3 2 218356857-218368099 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 20.0;testis: 7.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 11.7;Early spermatids: 13.6;Endometrial ciliated cells: 36.1;Late spermatids: 18.6;Proximal tubular cells: 11.3;Spermatocytes: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "BEWO: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044818 Supported NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA044818: AB_10959301" "unprognostic (7.11e-3)" "unprognostic (2.37e-1)" "unprognostic (3.95e-2)" "unprognostic (1.70e-3)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.35e-1)" "unprognostic (2.40e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-2)" "unprognostic (1.69e-2)" "unprognostic (3.44e-1)" "unprognostic (1.95e-3)" "unprognostic (1.46e-1)" "unprognostic (2.72e-1)" "unprognostic (9.93e-2)" "unprognostic (1.19e-1)" 0.1 0.1 0.9 0.0 0.9 0.1 0.0 0.7 0.5 1.3 6.0 0.0 0.0 0.4 4.9 0.0 20.0 0.3 0.0 0.9 1.4 3.4 0.0 2.2 0.0 2.5 3.4 0.1 1.1 1.8 1.3 0.8 2.0 1.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.5 0.2 0.1 7.3 1.2 0.0 3.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.9 0.7 0.5 0.9 1.4 2.5 3.4 2.0 2.5 1.2 1.5 0.1 0.0 0.5 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.7 2.8 0.0 5.5 0.0 2.2 0.0 0.0 11.7 1.4 13.6 36.1 0.4 0.2 0.0 0.0 0.9 0.2 1.3 0.1 1.1 0.8 0.0 0.1 0.7 0.1 1.3 0.0 0.6 0.0 0.0 2.7 0.0 18.6 0.6 1.8 0.0 1.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 11.3 0.7 0.1 0.0 0.2 0.2 10.2 0.1 0.0 0.0 4.7 0.1 0.3 0.0 0.1 CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2160.5;Alveolar cells type 1: 3557.7;Basal keratinocytes: 1375.3;Endothelial cells: 1024.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 2140.5;BJ hTERT+: 2371.6;HBEC3-KT: 2333.7;LHCN-M2: 2372.1;U-138 MG: 1894.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" 621.1 17.4 12.7 44.7 15.3 0.6 284.5 14.3 21.6 267.0 11.8 298.8 32.3 190.9 72.5 135.1 152.5 148.2 276.5 12.2 13.9 18.4 26.6 592.0 30.3 15.1 13.4 137.4 24.6 21.4 6.8 449.2 14.6 110.3 93.6 31.4 58.0 175.5 102.9 104.9 89.4 274.2 14.3 199.1 120.8 25.8 16.1 25.2 168.4 184.6 20.3 202.0 124.1 16.2 458.7 344.3 9.5 3.7 1406.6 2140.5 20.6 1055.8 2371.6 566.0 591.2 3.0 652.4 0.1 365.8 1228.5 494.8 828.2 2.2 2333.7 840.3 36.0 19.5 0.4 128.7 0.3 196.9 0.1 2.1 736.9 481.6 805.7 536.0 539.0 1749.9 0.2 0.3 23.4 2372.1 45.2 0.5 0.8 33.7 1.2 173.9 5.2 25.2 251.0 317.0 2.0 1.0 0.6 328.3 20.1 52.3 137.8 1.6 3.9 1349.3 1894.8 212.4 730.6 298.9 96.8 15.8 1.9 758.4 0.9 701.0 14.6 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 12.7 15.3 14.3 21.6 12.2 13.9 15.1 13.4 14.6 14.3 16.1 16.2 2160.5 3557.7 123.0 0.0 15.8 1375.3 392.0 534.8 316.4 8.3 17.9 190.8 286.6 107.2 342.0 7.3 2.1 64.3 7.0 0.3 5.9 76.8 2.6 17.5 102.3 1024.0 1.8 16.0 0.4 0.7 449.5 326.8 1.5 21.3 13.9 6.3 450.5 5.2 15.0 0.0 0.5 7.0 20.3 11.0 187.1 13.4 377.2 10.7 439.4 19.7 3.7 249.0 0.0 1.0 1.3 43.1 0.1 565.4 56.2 512.7 0.7 0.3 30.6 7.7 558.8 152.4 751.4 2.1 5.7 39.4 610.9 117.0 16.7 59.7 2.4 93.3 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" 91.6 61.0 35.1 19.1 34.6 7.8 75.3 37.4 40.6 48.5 36.0 117.8 19.2 74.2 31.1 25.1 60.6 15.3 90.3 34.5 35.3 37.7 50.3 43.6 15.4 35.5 35.7 32.3 62.7 12.8 33.0 13.9 36.0 55.9 16.8 13.9 26.6 29.2 64.4 32.5 47.1 28.2 34.7 41.2 74.4 17.1 37.3 26.0 31.4 22.4 14.4 76.6 39.1 35.0 17.9 15.7 12.8 16.3 63.3 40.3 7.4 29.5 26.4 18.5 17.2 7.2 5.2 11.5 12.8 38.9 47.6 5.9 9.6 14.2 13.6 34.4 15.3 5.5 25.1 18.3 15.0 8.5 20.1 24.1 16.6 19.8 15.3 34.4 13.1 19.2 7.2 21.7 23.4 11.6 9.5 12.6 9.5 12.6 48.2 13.7 2.9 9.3 62.8 9.6 8.4 14.0 15.2 21.1 15.4 9.5 11.1 10.4 16.7 29.5 16.3 21.6 27.3 9.6 15.4 23.1 54.6 13.5 26.2 33.3 39.3 20.1 128.7 43.2 168.8 79.5 111.6 113.8 45.0 79.5 53.2 74.2 7.8 69.3 25.9 123.8 140.8 75.1 35.1 34.6 37.4 40.6 34.5 35.3 35.5 35.7 36.0 34.7 37.3 35.0 68.7 67.3 25.0 11.1 104.8 70.2 38.0 76.9 8.6 31.9 39.2 65.3 0.7 60.1 48.4 82.8 8.4 15.0 175.2 143.9 17.6 74.1 7.6 33.5 34.1 36.1 88.1 15.8 8.6 140.2 66.2 60.0 121.8 30.5 34.3 24.4 53.9 77.3 90.9 32.0 10.2 100.5 69.2 46.9 185.9 28.3 59.4 82.0 113.8 13.1 43.5 57.2 133.9 7.5 10.8 86.7 108.6 102.3 53.3 45.3 146.7 66.9 48.2 34.1 118.3 33.7 135.3 37.9 63.1 17.8 66.9 13.8 132.7 44.9 51.7 29.5 CCDC125 KENAE ENSG00000183323 "Coiled-coil domain containing 125" Q86Z20 5 69280175-69332809 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.0;neutrophil: 11.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.0" "Cell line enhanced" "Detected in many" "T-47d: 27.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041878 Approved Uncertain "Nucleoplasm,Nuclear membrane,Intermediate filaments" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane, Intermediate filaments" Nucleoplasm "HPA041878: AB_10796787" "prognostic unfavorable (8.06e-4)" "unprognostic (1.01e-1)" "unprognostic (2.35e-2)" "prognostic favorable (4.40e-4)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "unprognostic (8.21e-2)" "unprognostic (3.08e-2)" "unprognostic (4.06e-2)" "unprognostic (5.07e-2)" "unprognostic (2.52e-2)" "unprognostic (1.91e-2)" "unprognostic (2.05e-2)" "unprognostic (5.40e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "prognostic favorable (2.51e-4)" 3.3 3.9 2.3 2.9 2.4 10.9 7.0 2.6 2.8 2.8 2.7 4.8 4.9 2.7 2.6 4.5 3.6 3.3 2.1 2.1 2.5 3.8 12.9 3.3 2.9 2.7 2.7 3.0 5.1 3.2 4.3 3.9 3.2 6.9 5.6 3.2 6.6 1.9 2.0 3.8 5.4 1.3 2.0 3.5 5.9 1.4 2.5 2.4 2.9 1.1 2.4 3.2 2.9 3.5 3.1 5.0 0.9 14.0 1.6 0.9 17.9 1.8 2.6 1.2 0.7 4.4 15.3 5.5 10.4 2.1 1.1 3.9 10.3 5.3 1.1 19.4 8.1 3.5 7.5 8.6 4.2 3.9 1.9 5.5 2.6 5.7 1.7 2.8 2.0 6.6 10.6 2.3 1.1 12.5 4.9 6.1 0.2 3.9 3.2 7.2 0.0 7.4 6.7 3.5 5.8 3.6 3.7 8.2 2.8 0.2 27.0 3.9 2.3 1.1 2.0 3.4 2.9 10.8 17.8 2.0 3.5 20.5 0.5 6.9 1.0 15.0 1.1 1.0 0.9 1.1 0.9 0.8 1.7 0.8 0.8 0.5 11.4 1.1 2.8 1.3 0.7 0.9 2.3 2.4 2.6 2.8 2.1 2.5 2.7 2.7 3.2 2.0 2.5 3.5 4.7 25.6 20.4 21.9 5.7 1.0 4.0 8.5 7.4 4.7 13.4 10.3 5.9 7.2 16.8 1.8 2.1 34.2 4.4 11.0 5.9 13.7 0.9 31.6 5.6 3.4 1.2 9.2 17.2 12.2 8.5 5.5 28.5 15.1 15.8 9.9 1.8 17.9 6.1 3.3 16.7 14.1 10.2 4.1 2.7 1.9 2.1 8.7 1.8 17.8 7.8 4.5 5.2 16.1 13.4 8.6 17.1 2.2 6.9 5.5 9.6 8.9 60.7 7.4 0.0 5.3 4.7 1.8 3.1 8.5 1.0 12.4 5.2 14.1 7.9 4.8 CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 87.6;retina: 52.5;testis: 185.7" "Group enriched" "Detected in many" 4 "Early spermatids: 780.2;Late spermatids: 2032.0" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 30.5;U-937: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" 1.8 3.7 37.2 1.9 24.4 0.8 1.7 42.7 39.9 5.2 6.2 20.1 1.6 9.3 2.2 1.7 3.3 2.2 5.7 24.2 34.7 0.7 0.3 1.1 2.7 30.5 54.2 2.8 0.8 1.6 6.4 1.4 26.3 12.1 3.1 52.5 1.6 13.6 4.4 0.9 4.8 11.6 34.9 1.5 4.6 185.7 87.6 5.2 1.3 4.0 1.7 13.1 3.9 30.6 1.1 1.5 11.7 7.9 6.3 5.4 2.0 4.7 6.0 4.6 4.3 1.8 1.0 6.5 0.5 6.2 18.4 2.5 7.8 0.9 4.3 17.2 7.7 10.7 3.1 0.0 2.2 1.5 22.2 6.0 0.8 5.0 0.4 4.1 2.7 10.0 4.0 6.0 1.9 2.3 8.0 3.4 16.3 0.1 5.1 19.5 2.3 2.9 0.3 2.4 7.4 20.4 2.9 3.3 5.1 4.1 0.3 3.1 2.4 7.4 4.2 3.7 3.5 3.4 1.6 6.1 30.5 46.2 1.9 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 37.2 24.4 42.7 39.9 24.2 34.7 30.5 54.2 26.3 34.9 87.6 30.6 1.6 0.0 0.5 11.4 1.1 0.5 0.9 0.1 1.8 306.0 0.6 3.8 7.5 1.5 0.7 0.0 98.0 0.1 2.2 0.0 0.0 0.7 780.2 0.3 2.2 2.0 0.0 0.4 23.3 1.5 0.3 2.6 1.5 0.1 0.0 1.9 1.1 0.0 6.8 40.4 48.0 0.1 0.0 0.6 1.6 2032.0 18.0 2.3 0.0 10.3 0.7 22.5 2.1 28.6 13.3 0.6 0.1 7.5 1.1 0.9 0.0 0.2 2.0 20.7 6.6 1.6 6.1 321.9 17.2 0.1 0.4 0.4 3.4 0.3 0.0 0.3 CCDC146 "KIAA1505, MBO2" ENSG00000135205 "Coiled-coil domain containing 146" Q8IYE0 7 77122434-77329533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 308.3;Endometrial ciliated cells: 460.8;Oligodendrocyte precursor cells: 151.3;Respiratory ciliated cells: 417.9;Spermatocytes: 149.4" "Group enriched" "Detected in all" 4 "endometrial cancer: 8.8;ovarian cancer: 13.6;renal cancer: 15.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.4" "Group enriched" "Detected in many" 4 "granulocytes: 15.4;NK-cells: 5.3;T-cells: 4.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA020082, HPA020105" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA020082: AB_1852410, HPA020105: AB_2072056" "unprognostic (3.07e-3)" "unprognostic (9.94e-3)" "unprognostic (1.56e-1)" "unprognostic (2.54e-3)" "unprognostic (1.85e-1)" "prognostic favorable (7.37e-4)" "unprognostic (1.95e-3)" "unprognostic (8.02e-3)" "unprognostic (4.05e-4)" "unprognostic (1.73e-1)" "unprognostic (4.63e-1)" "unprognostic (4.09e-2)" "unprognostic (7.38e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-1)" "unprognostic (2.70e-3)" "unprognostic (5.58e-3)" 2.2 1.1 4.0 2.5 3.7 1.7 2.4 2.0 2.5 4.5 18.3 3.8 2.4 4.6 2.5 3.6 34.0 3.1 1.8 2.7 4.4 4.2 1.8 5.2 3.0 11.5 11.4 3.3 2.5 3.9 3.8 1.9 7.4 3.7 2.7 14.5 4.1 2.3 1.1 9.4 2.8 3.0 7.8 3.7 3.3 21.5 3.9 3.1 7.7 1.6 2.7 3.1 3.9 6.3 0.6 0.9 2.7 1.4 1.7 1.7 0.3 0.7 0.6 0.7 1.1 0.0 4.6 1.4 0.1 0.2 2.6 0.9 0.4 0.8 1.1 1.9 0.3 1.8 1.5 0.8 0.5 1.8 1.3 0.8 1.3 1.2 0.2 2.2 0.6 1.4 0.0 1.4 0.1 0.2 1.5 2.9 0.3 0.6 0.6 4.0 0.4 0.2 2.8 0.5 2.0 1.3 1.0 0.9 0.6 0.8 0.8 0.6 0.9 1.0 0.4 1.4 0.4 2.7 4.5 1.2 2.3 2.7 2.3 0.9 0.6 14.3 4.4 0.9 3.0 1.2 1.9 3.1 0.8 0.2 1.2 2.0 15.4 5.3 0.4 2.0 1.6 0.8 4.0 3.7 2.0 2.5 2.7 4.4 11.5 11.4 7.4 7.8 3.9 6.3 6.9 3.2 9.7 34.0 3.6 7.1 2.6 16.9 6.2 8.6 2.7 4.6 32.0 2.8 56.9 5.5 62.6 1.2 9.3 2.8 21.5 3.2 308.3 460.8 11.1 4.8 1.8 0.4 49.0 1.6 0.7 15.4 6.1 106.0 6.3 6.1 23.6 0.8 1.6 5.0 48.8 1.4 24.4 3.5 7.1 52.4 12.2 4.5 5.4 50.6 2.0 12.1 20.6 151.3 62.8 1.7 5.2 6.4 3.7 5.8 2.9 30.1 417.9 55.1 6.6 15.6 11.6 149.4 10.8 5.5 3.4 2.5 8.6 7.2 4.0 5.4 CCDC188 ENSG00000234409 "Coiled-coil domain containing 188" H7C350 22 20148416-20151055 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 40.2" "Group enriched" "Detected in some" 89 "Early spermatids: 313.0;Late spermatids: 988.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in some" "AF22: 4.0;SCLC-21H: 5.5;SH-SY5Y: 7.2;TIME: 3.1;U-2 OS: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049901 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA049901: AB_2680943" "unprognostic (9.83e-2)" "unprognostic (3.09e-2)" "unprognostic (9.79e-2)" "unprognostic (6.42e-3)" "unprognostic (2.45e-1)" "unprognostic (3.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.02e-1)" "unprognostic (8.43e-2)" "unprognostic (4.08e-3)" "unprognostic (1.67e-5)" "unprognostic (1.16e-1)" "unprognostic (5.37e-5)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-2)" 1.5 0.6 0.4 0.5 0.6 0.5 1.3 0.5 0.6 0.8 0.0 0.5 0.8 0.8 0.0 0.3 1.0 0.3 0.6 1.0 1.3 0.9 0.2 1.0 0.6 0.1 0.0 0.3 0.5 0.0 9.6 0.6 0.0 0.5 0.0 0.2 0.4 0.0 0.6 1.1 0.6 0.2 0.0 1.5 0.5 40.2 1.4 0.0 0.6 0.0 0.0 0.7 0.6 0.0 0.0 0.0 4.0 0.2 0.0 0.5 0.0 1.1 0.5 0.9 0.7 0.0 0.1 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 1.1 0.2 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.2 2.6 0.8 0.3 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 5.5 7.2 0.4 0.0 0.4 0.1 0.0 0.1 3.1 1.6 3.0 2.0 0.2 0.5 0.1 0.2 2.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.6 0.5 0.6 1.0 1.3 0.1 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.0 7.3 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 988.5 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 4.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 21.7;HMC-1: 83.3;Karpas-707: 22.0;THP-1: 34.5;U-937: 25.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" 8.5 6.7 14.9 15.1 15.1 47.6 5.3 20.1 21.6 5.6 15.3 17.8 4.0 3.5 0.3 12.9 6.5 8.5 5.5 15.3 15.0 6.5 7.3 21.1 28.6 17.2 15.5 3.1 4.1 0.9 4.5 1.7 17.5 7.8 3.6 1.4 14.4 2.5 1.2 4.5 34.1 1.2 15.4 86.1 8.9 17.4 15.4 17.4 5.4 0.8 13.8 8.3 7.7 15.9 0.3 1.3 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 3.4 19.7 2.9 1.1 0.5 1.6 0.1 0.6 0.0 21.7 0.0 15.0 4.6 1.1 0.8 9.4 83.3 0.0 0.0 0.2 0.0 1.3 0.5 6.3 0.5 22.0 0.7 0.9 12.7 7.7 0.7 3.7 0.5 11.9 0.3 18.5 0.3 0.3 4.8 0.0 0.0 0.5 1.1 0.1 2.6 34.5 0.0 0.0 0.7 0.1 0.2 4.7 1.5 15.8 1.0 25.3 0.4 2.9 4.6 6.7 3.5 3.6 1.0 1.6 2.0 2.9 1.6 2.0 1.8 2.2 9.2 6.5 2.5 2.7 0.6 1.3 14.9 15.1 20.1 21.6 15.3 15.0 17.2 15.5 17.5 15.4 15.4 15.9 3.3 0.0 10.7 5.2 30.3 2.7 4.5 10.5 0.6 45.2 5.7 4.8 13.5 4.3 9.9 9.2 0.0 2.9 34.9 46.0 0.0 12.8 11.1 8.7 2.6 4.4 18.0 7.0 2.6 28.9 5.8 3.1 51.0 6.8 26.6 2.2 6.1 10.4 14.5 0.0 2.0 24.4 8.2 26.0 26.6 15.8 1.5 27.3 5.4 12.2 35.0 15.4 64.9 2.0 0.6 35.0 33.2 0.7 24.9 2.9 36.1 3.2 22.7 4.7 0.0 2.8 2.8 13.7 8.7 2.0 1.6 1.4 31.7 10.0 32.4 15.7 CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.0;Collecting duct cells: 20.2;Ductal cells: 30.0;Pancreatic endocrine cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 4.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.3" "Cell line enhanced" "Detected in many" "HaCaT: 122.5;hTERT-RPE1: 110.8;WM-115: 138.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" 4.9 10.3 9.5 7.7 13.1 2.8 8.1 10.9 10.7 12.0 15.0 73.4 9.9 23.9 7.3 33.2 10.8 12.0 53.0 9.0 12.7 10.2 5.0 12.3 3.3 13.1 12.6 4.0 25.3 11.3 10.2 3.9 12.7 16.2 12.5 4.3 28.3 22.7 67.4 15.4 18.1 24.2 11.6 5.6 22.3 8.3 12.7 1.3 45.2 65.1 5.9 25.9 16.7 12.6 50.0 6.8 0.0 0.4 1.1 4.6 2.5 14.8 14.6 16.1 15.6 0.5 44.7 0.3 20.1 47.8 58.6 122.5 0.2 40.4 15.1 0.0 0.3 14.9 64.4 4.7 8.5 0.2 2.8 5.7 9.0 6.9 20.3 110.8 11.6 0.8 0.1 0.7 27.9 0.0 0.5 0.0 0.2 23.1 12.7 0.0 4.2 0.2 48.0 2.8 0.1 3.6 8.8 19.1 8.4 0.2 1.9 2.3 62.1 29.7 47.2 7.9 39.8 0.0 0.1 0.6 36.2 2.8 138.3 4.3 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 0.4 0.1 0.2 0.0 0.2 9.5 13.1 10.9 10.7 9.0 12.7 13.1 12.6 12.7 11.6 12.7 12.6 2.7 12.8 10.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.5 3.0 0.0 0.0 1.3 20.2 0.0 0.0 0.2 0.0 1.9 30.0 0.0 1.8 0.4 0.6 0.0 0.0 0.0 3.7 0.1 0.6 0.0 2.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 165.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 42.6;ASC TERT1: 113.8;HeLa: 62.7;HSkMC: 46.5;U-2197: 375.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 394.6 41.5 1.8 0.7 2.0 0.2 116.5 0.9 2.9 355.7 0.7 23.6 0.7 35.3 0.7 25.4 39.0 7.7 161.1 1.6 1.3 0.7 5.6 136.4 1.9 1.4 1.4 147.1 4.4 0.6 0.8 1.4 1.4 37.0 1.6 0.1 30.7 25.5 39.2 197.1 11.5 6.5 1.0 4.0 11.4 33.1 1.4 1.3 14.2 5.1 0.4 36.7 111.6 1.5 0.0 3.7 0.1 0.0 42.6 113.8 0.0 0.2 1.2 0.1 0.2 0.0 0.0 0.1 0.5 0.7 3.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 62.7 0.0 0.1 0.1 0.1 46.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.1 0.3 0.0 1.9 0.2 0.0 0.1 0.2 375.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.0 0.9 2.9 1.6 1.3 1.4 1.4 1.4 1.0 1.4 1.5 25.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370854-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.5;Langerhans cells: 32.6;Macrophages: 12.8;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 39.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;Karpas-707: 6.8;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" 1.8 2.0 0.5 15.0 0.6 1.3 2.4 0.6 0.7 2.1 1.0 3.3 4.1 1.4 1.0 1.4 1.7 5.0 1.1 0.4 0.8 1.0 3.4 7.4 14.4 1.6 0.9 1.7 0.6 0.6 0.4 0.7 1.3 1.9 3.9 0.1 2.9 1.0 0.3 1.1 5.8 3.2 1.2 9.4 6.8 0.8 1.2 4.2 0.8 0.2 9.4 4.8 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 3.1 0.0 0.0 0.1 0.0 12.0 2.2 0.0 11.0 3.8 39.7 0.5 4.7 16.1 9.5 0.0 0.4 4.1 0.5 6.3 0.0 9.0 8.0 3.2 0.5 0.6 0.6 0.7 0.4 0.8 1.6 0.9 1.3 1.2 1.2 2.4 0.3 0.0 1.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.3 1.5 0.0 1.3 0.0 1.4 0.3 4.7 0.0 0.0 0.0 0.0 5.5 32.6 0.0 0.0 12.8 3.6 1.9 1.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 13.1 0.1 0.0 0.1 CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139696 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 35.8" "Group enriched" "Detected in many" 4 "B-cells: 44.0;Late spermatids: 26.4;T-cells: 40.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 77.4;T-cells: 74.5" "Group enriched" "Detected in some" 6 "Hep G2: 9.4;OE19: 3.2" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Not detected" "Not detected" "CAB006820, HPA014488" Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" "CAB006820: , HPA014488: AB_1846639" "unprognostic (1.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.07e-3)" "unprognostic (2.08e-1)" "unprognostic (8.43e-2)" "unprognostic (2.05e-4)" "unprognostic (2.39e-1)" "unprognostic (4.98e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-4)" "unprognostic (3.74e-2)" "unprognostic (7.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" 0.5 0.2 0.5 11.4 0.5 2.5 2.2 0.2 0.7 0.9 0.1 1.9 2.8 0.4 0.6 1.4 0.6 2.1 0.1 0.6 0.3 0.5 0.6 1.2 18.1 0.3 0.3 0.2 0.1 0.1 0.0 0.1 0.3 1.0 2.2 1.4 0.6 0.3 0.1 2.4 6.6 0.4 0.2 12.5 3.6 2.7 0.5 3.6 0.6 0.1 35.8 4.4 0.0 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.8 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.3 0.0 0.2 9.4 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.3 0.2 0.1 0.0 0.1 0.4 0.3 0.2 0.4 4.5 0.0 74.5 69.0 30.7 11.6 17.5 77.4 0.3 0.2 0.7 1.5 0.1 2.1 58.7 6.9 0.5 0.5 0.2 0.7 0.6 0.3 0.3 0.3 0.3 0.2 0.5 0.4 0.7 0.0 4.2 1.0 44.0 1.0 0.3 0.0 0.0 0.8 2.1 1.1 0.0 0.0 1.9 0.0 2.1 0.1 3.0 0.0 1.9 0.2 8.6 0.8 0.3 1.0 0.0 0.4 1.8 0.2 0.0 0.9 4.1 0.3 2.5 0.2 1.1 0.8 0.1 0.0 1.1 2.0 0.0 0.0 7.3 26.4 0.0 5.5 1.8 0.0 3.7 0.5 0.0 1.0 0.3 0.1 0.1 0.4 5.5 0.2 4.6 0.4 0.9 3.8 0.0 0.7 0.5 2.2 0.4 0.1 0.4 0.1 40.1 0.1 0.8 0.1 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 16.8" "Cell type enhanced" "Detected in some" "dendritic cells: 28.4;Kupffer cells: 17.7;NK-cells: 66.9;T-cells: 21.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 472.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 472.1" "Cell line enhanced" "Detected in some" "HEL: 20.6;HMC-1: 69.4;NB-4: 14.4;U-937: 28.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 280000 "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.11e-3)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (6.95e-6)" "unprognostic (5.79e-2)" "unprognostic (1.43e-4)" "unprognostic (1.93e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (5.40e-4)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" 2.1 0.4 0.3 3.7 0.4 10.0 0.4 0.3 0.5 0.3 0.3 1.1 3.0 0.3 0.3 0.4 0.5 1.0 0.6 0.4 0.3 0.3 4.2 3.3 3.4 0.4 0.3 1.0 0.1 0.1 0.1 0.4 0.3 0.4 1.4 0.0 1.1 0.4 0.3 0.3 2.8 1.1 0.3 16.8 1.0 2.7 0.3 2.8 0.2 0.2 2.0 1.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.4 6.8 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 2.1 14.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 2.6 1.1 0.1 0.0 28.7 0.0 472.1 43.3 107.9 71.3 59.1 35.2 0.3 3.7 39.7 41.0 0.2 5.3 36.0 3.1 78.5 73.6 2.4 0.2 70.7 0.3 0.4 0.3 0.5 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.1 3.2 6.1 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 5.2 0.0 0.1 0.2 0.0 2.1 0.7 1.7 0.0 0.3 0.5 0.1 3.8 0.0 0.7 0.2 0.6 0.0 0.1 0.0 0.0 17.7 3.1 2.4 1.8 8.3 0.0 0.0 8.5 0.0 66.9 0.0 0.2 0.0 0.0 2.2 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 0.1 0.0 21.9 0.5 0.0 0.0 CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 9 "dendritic cells: 492.1;NK-cells: 727.1;T-cells: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 25 "HDLM-2: 155.9;JURKAT: 113.1;MOLT-4: 167.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" 3.2 1.7 2.3 25.3 2.3 49.0 1.9 2.2 2.5 1.9 1.9 4.3 7.1 2.3 3.1 2.1 1.8 5.5 1.3 2.3 2.3 2.0 5.4 10.9 57.7 2.3 2.2 0.8 0.8 0.5 0.8 1.4 2.2 1.8 4.6 0.2 2.4 1.6 1.4 1.1 14.3 1.5 2.1 40.2 7.0 0.4 2.9 179.4 2.5 0.9 36.4 7.3 1.9 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 155.9 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.1 0.0 0.0 167.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 8.3 1.0 0.4 376.4 1.4 208.9 9.3 190.0 219.7 1.5 4.9 237.8 195.1 8.7 225.3 1.2 2.8 254.5 231.2 2.3 2.3 2.2 2.5 2.3 2.3 2.3 2.2 2.2 2.1 2.9 2.5 3.4 3.2 16.0 3.3 8.2 1.5 0.1 0.0 0.6 0.4 3.5 3.2 0.6 1.5 1.3 0.0 0.0 0.1 492.1 0.4 0.0 0.5 0.2 0.7 0.8 1.8 0.0 14.7 8.8 0.0 0.1 2.2 6.1 1.1 6.3 0.4 7.1 1.4 0.3 3.3 9.4 0.5 0.0 7.8 1.4 0.2 0.0 5.9 3.6 14.0 7.6 0.1 727.1 0.5 3.7 0.0 1.2 0.0 51.9 0.1 0.2 1.3 2.2 0.2 0.0 0.9 1.2 0.1 2.5 1.4 0.6 0.1 247.2 0.0 0.1 0.1 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "granulocytes: 15.2;Hofbauer cells: 32.1;Kupffer cells: 26.3;Langerhans cells: 15.3;Macrophages: 36.1;monocytes: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.1;HMC-1: 33.1;THP-1: 6.5;U-937: 16.2" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" 4.0 1.3 0.7 6.8 1.1 9.7 0.8 0.8 5.5 0.6 1.1 1.3 1.1 0.6 0.1 0.6 0.7 2.0 0.9 0.7 1.4 0.7 1.5 8.4 2.1 1.7 1.8 0.3 0.6 0.4 0.4 2.9 2.1 0.5 1.3 0.0 0.7 0.5 0.3 0.4 1.2 3.1 1.4 7.3 0.7 0.3 2.7 1.0 1.0 0.2 1.1 3.8 0.4 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 3.3 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 16.2 0.0 51.8 142.1 7.0 0.7 228.3 0.4 2.7 0.3 0.3 158.8 2.4 0.2 0.2 5.2 43.9 242.7 10.5 0.2 64.6 0.7 1.1 0.8 5.5 0.7 1.4 1.7 1.8 2.1 1.4 2.7 2.2 0.1 0.0 1.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 15.2 0.0 0.0 0.2 32.1 0.0 0.0 0.0 0.0 26.3 15.3 0.1 0.0 36.1 1.8 1.0 19.6 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 1.3 0.0 0.0 0.0 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.5" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Langerhans cells: 9.3;Muller glia cells: 16.0;T-cells: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 138.2" "Lineage enriched" "Detected in many" 33 "T-cells: 138.2" "Group enriched" "Detected in some" 66 "JURKAT: 21.0;MOLT-4: 70.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" 1.4 0.9 0.4 22.6 0.4 12.2 1.0 0.1 0.5 0.9 0.0 2.8 3.1 0.7 0.4 2.3 0.8 4.9 0.9 0.6 0.4 0.8 1.5 5.7 38.0 0.2 0.0 0.8 0.4 0.2 0.4 0.3 0.5 1.0 2.7 1.8 6.4 0.3 0.6 1.4 7.1 1.2 0.0 14.1 7.9 0.8 0.3 46.5 1.0 0.3 22.2 6.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.1 70.5 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.6 45.9 0.4 32.8 1.5 108.7 72.5 3.7 3.4 88.4 69.8 1.8 0.4 3.4 4.1 138.2 61.5 0.4 0.4 0.1 0.5 0.6 0.4 0.2 0.0 0.5 0.0 0.3 0.0 0.4 0.0 1.7 0.0 4.1 0.9 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 2.7 0.0 0.1 0.2 0.0 1.3 0.3 0.0 0.0 0.9 2.6 0.1 1.3 0.0 1.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 9.3 0.9 0.0 1.8 3.6 0.0 2.1 16.0 1.0 0.0 0.1 0.1 0.3 0.0 6.3 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.6 0.4 0.7 0.2 0.3 0.0 57.0 0.0 0.2 0.2 CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1861.9;granulocytes: 568.6;Hofbauer cells: 562.6;Langerhans cells: 674.3;Macrophages: 690.5;monocytes: 814.2;NK-cells: 602.5;T-cells: 1300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Daudi: 708.6;REH: 1042.2;U-266/84: 1087.0;U-698: 1159.2" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" 62.1 10.2 10.2 297.8 13.5 266.9 59.5 9.6 38.5 26.1 12.6 68.6 41.7 21.3 36173.0 35.0 18.4 89.2 18.0 10.3 10.0 18.7 55.0 449.2 1082.0 11.3 10.0 9.6 8.2 5.4 6.1 16.9 10.5 19.2 96.9 0.2 37.6 104.2 9.4 27.9 294.7 47.4 10.1 646.5 87.2 4.7 16.5 1051.6 24.9 13.8 1256.4 134.9 13.1 10.5 2.0 0.0 0.3 0.0 0.0 1.4 14.3 0.1 1.0 0.1 0.0 0.3 0.6 708.6 1.4 0.0 0.3 0.1 0.0 0.2 0.0 0.5 0.2 34.8 0.0 1.4 0.0 7.5 106.4 0.0 0.0 0.2 0.0 0.7 0.0 44.9 23.7 1.0 0.0 4.6 8.5 62.9 3.0 0.5 0.0 1042.2 0.9 16.6 0.0 0.0 2.1 9.3 0.4 1.1 1.3 9.2 0.3 12.5 1.6 0.0 2.7 0.7 1.2 2.9 1087.0 1159.2 0.1 17.8 0.1 599.3 4558.9 9769.3 6605.8 7389.3 5319.0 10570.4 8177.1 6530.7 3180.2 10064.7 5495.2 5664.3 334.5 3732.1 6667.9 1034.9 11684.0 22571.2 10.2 13.5 9.6 38.5 10.3 10.0 11.3 10.0 10.5 10.1 16.5 10.5 9.5 67.3 194.6 0.0 1861.9 45.4 0.8 0.2 3.4 0.0 8.4 5.8 6.2 14.3 50.1 49.7 0.0 4.7 415.9 1.9 0.0 1.3 0.8 3.9 2.6 29.5 0.0 60.6 0.3 0.2 5.8 18.1 29.6 7.1 568.6 0.0 17.5 3.6 562.6 0.0 0.1 2.3 0.0 262.6 674.3 1.4 0.0 690.5 106.7 1.9 814.2 0.0 602.5 0.0 0.1 0.2 2.8 0.0 133.7 3.1 0.7 11.5 17.5 0.0 0.0 7.3 9.1 0.3 0.5 3.2 31.4 5.6 1300.0 0.0 2.7 1.1 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 9 "dendritic cells: 625.0;NK-cells: 1299.7;T-cells: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Cell line enhanced" "Detected in some" "Hep G2: 52.0;JURKAT: 26.7;MOLT-4: 119.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" 8.2 1.3 0.7 32.9 0.8 28.6 2.6 0.8 1.3 2.5 0.9 7.3 12.4 3.0 0.4 3.9 3.9 3.2 1.8 0.6 1.1 7.1 7.7 17.1 36.8 1.4 0.8 0.8 1.2 0.1 1.4 3.3 1.0 4.4 1.9 0.0 3.1 1.0 0.8 1.7 21.1 1.1 1.2 53.7 8.1 0.6 1.1 48.8 3.5 0.1 14.8 3.9 3.9 1.2 0.0 0.0 0.0 0.0 0.1 0.4 12.9 0.0 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.7 52.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 26.7 0.1 0.0 0.1 0.0 119.2 0.0 0.0 0.0 0.2 0.1 0.1 2.3 0.2 0.0 0.4 0.3 1.8 1.1 0.0 0.3 0.0 0.0 0.0 0.3 0.3 1.0 0.0 1.2 0.2 0.0 0.2 0.0 0.0 0.5 0.4 0.5 66.6 0.2 57.6 0.4 29.8 49.0 0.3 0.2 69.4 71.5 2.3 231.5 0.6 6.9 28.7 30.9 0.7 0.8 0.8 1.3 0.6 1.1 1.4 0.8 1.0 1.2 1.1 1.2 5.3 0.0 0.0 0.0 12.1 7.5 0.6 0.1 1.8 0.0 4.2 3.7 0.5 4.3 0.3 0.0 0.0 0.7 625.0 9.4 0.0 1.3 0.1 2.8 2.0 4.5 0.0 47.7 0.0 0.5 10.3 12.4 43.8 5.3 8.2 0.0 16.8 3.3 3.6 1.7 0.0 1.5 0.0 18.5 8.8 0.0 0.0 19.2 12.4 0.0 11.6 0.0 1299.7 0.0 0.0 0.1 5.8 0.0 82.7 3.8 8.1 1.4 0.5 0.0 0.0 0.5 3.9 0.0 1.3 1.0 4.4 1.9 527.4 0.0 2.1 3.8 CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609979-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 65.0" "Cell type enhanced" "Detected in many" "B-cells: 95.6;dendritic cells: 18.3;Hofbauer cells: 18.7;Kupffer cells: 25.6;Macrophages: 21.1;NK-cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 232.9;naive B-cell: 413.5" "Lineage enriched" "Detected in all" 20 "B-cells: 413.5" "Cell line enhanced" "Detected in some" "Daudi: 21.4;Karpas-707: 14.5;REH: 7.8;U-698: 44.4" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in single" "CAB002505, HPA044658" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Mitochondria" "CAB002505: AB_563629, HPA044658: AB_2679039" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (7.81e-2)" "unprognostic (7.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (2.49e-8)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.59e-2)" 4.5 2.3 1.9 20.6 2.0 6.7 1.7 2.0 3.3 1.4 4.2 1.9 1.3 1.0 4.8 0.6 1.2 4.1 0.7 1.8 1.8 2.2 6.0 2.8 65.0 2.8 1.8 0.8 2.2 1.1 2.5 3.3 2.4 1.5 1.3 0.4 1.6 0.7 0.6 2.0 8.4 1.6 1.9 53.6 2.6 0.8 3.3 6.9 2.4 0.0 50.2 4.2 0.9 2.3 0.1 0.0 0.6 0.5 0.9 5.2 0.1 0.3 0.1 0.4 0.7 0.0 0.2 21.4 0.1 0.3 0.1 0.0 0.0 0.1 0.5 1.8 0.4 0.6 0.2 0.0 0.5 0.3 4.1 1.5 0.0 0.2 0.4 0.9 0.0 4.9 0.0 14.5 1.1 0.0 0.3 2.7 0.2 0.0 0.1 7.8 0.0 5.5 0.0 0.0 0.3 0.5 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.7 0.2 0.2 0.0 0.3 0.3 44.4 0.8 0.5 0.0 0.6 2.0 0.3 3.1 3.5 4.3 232.9 1.5 2.2 20.2 413.5 0.7 2.4 1.4 10.6 0.5 11.0 1.7 14.8 1.9 2.0 2.0 3.3 1.8 1.8 2.8 1.8 2.4 1.9 3.3 2.3 0.7 0.0 0.6 5.9 95.6 1.0 0.5 0.9 0.6 0.0 1.3 1.3 1.1 1.5 0.4 3.7 0.0 0.2 18.3 0.7 0.0 0.8 0.2 0.4 0.6 0.9 1.8 2.7 1.0 0.7 0.3 0.9 1.1 0.4 0.0 0.8 0.7 0.2 18.7 0.0 1.2 0.2 0.0 25.6 14.6 0.3 0.9 21.1 0.0 0.0 3.0 0.6 19.6 2.0 4.4 1.1 0.0 0.4 2.7 0.5 0.6 0.7 1.3 0.7 0.0 0.5 0.9 1.1 1.7 0.2 1.1 0.3 5.9 0.5 0.4 0.4 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 193.5;esophagus: 87.1;liver: 86.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 364.9;Hepatocytes: 107.8;Pancreatic endocrine cells: 120.2;Paneth cells: 400.5;Proximal enterocytes: 137.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1234.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 1234.7" "Cell line enhanced" "Detected in many" "A-431: 200.3;CAPAN-2: 141.9;HeLa: 207.1;PC-3: 107.0;SiHa: 249.9;U-937: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" 7.1 3.0 8.0 9.6 8.1 193.5 3.7 8.3 10.6 19.7 7.4 23.7 6.4 5.3 5.5 87.1 6.4 4.3 6.7 7.9 8.3 14.0 86.7 7.1 1.5 9.0 8.2 1.5 0.8 3.2 1.2 10.8 9.5 4.3 27.8 0.5 15.0 3.1 1.7 17.1 16.3 11.3 8.3 23.4 2.1 1.0 8.9 2.0 4.5 6.4 4.4 5.5 38.5 8.7 200.3 21.4 0.0 0.0 0.2 5.5 0.0 16.7 4.3 4.1 16.2 1.0 141.9 0.0 8.1 30.8 8.7 63.9 4.5 46.8 10.7 0.1 3.9 0.0 207.1 34.4 1.4 0.0 0.0 8.8 8.9 31.4 0.0 0.5 2.7 0.0 0.0 0.0 1.6 0.2 0.0 1.0 0.1 24.7 107.0 0.0 0.1 3.4 1.5 0.0 0.1 0.0 249.9 0.0 0.3 2.2 0.0 4.3 3.4 0.2 8.3 18.5 1.2 0.0 0.1 0.0 2.4 96.9 0.0 216.2 207.2 471.1 0.5 124.7 0.8 0.1 0.4 0.9 12.7 0.2 0.3 0.4 1234.7 0.4 110.8 3.1 0.7 86.8 8.0 8.1 8.3 10.6 7.9 8.3 9.0 8.2 9.5 8.3 8.9 8.7 9.9 3.2 1.1 0.3 1.2 1.5 0.1 2.4 0.0 0.2 0.2 0.3 2.6 1.5 2.7 5.5 0.0 1.1 0.0 364.9 43.0 7.5 0.8 2.1 2.6 42.7 0.0 6.1 0.2 1.5 6.4 9.1 0.0 20.3 0.0 0.0 47.2 107.8 5.9 0.0 0.3 23.1 85.5 60.7 0.9 1.0 0.3 36.6 0.0 5.6 61.5 0.1 0.0 0.5 0.0 120.2 400.5 0.0 3.0 2.1 137.6 0.6 0.4 0.1 0.0 1.3 1.3 0.0 1.2 6.3 1.1 2.5 1.7 0.0 19.8 0.8 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 320.3;Excitatory neurons: 447.6;Inhibitory neurons: 479.0;Oligodendrocyte precursor cells: 444.3;Oligodendrocytes: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 15.6 12.5 26.3 5.5 32.4 3.5 12.2 33.5 30.0 15.8 12.2 21.2 14.7 15.0 7.7 10.1 12.6 13.7 16.4 24.9 25.2 17.3 14.7 12.3 2.0 25.7 26.8 14.0 13.1 19.7 14.6 12.7 27.0 15.8 10.3 23.7 7.6 14.9 11.4 6.3 12.9 14.5 19.8 6.6 22.4 24.4 29.7 2.2 8.1 13.6 1.8 23.0 11.3 37.0 22.6 21.1 21.9 10.4 21.5 26.4 7.7 25.4 35.7 17.2 17.9 17.1 50.1 0.1 26.6 42.4 13.0 10.3 16.3 14.2 20.9 0.1 13.2 17.4 25.5 6.7 24.3 14.1 7.5 18.6 17.9 27.8 27.8 21.3 58.0 13.6 45.1 0.1 28.2 6.2 0.4 2.5 18.0 29.3 20.0 0.0 37.0 0.1 27.7 43.1 15.7 22.9 43.0 17.8 24.8 13.4 23.1 0.8 59.0 31.3 16.2 36.1 33.9 0.1 0.1 0.1 41.4 0.0 42.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 32.4 33.5 30.0 24.9 25.2 25.7 26.8 27.0 19.8 29.7 37.0 82.6 41.7 35.7 320.3 0.8 11.7 26.0 15.9 12.0 97.7 14.0 12.8 59.9 30.0 38.9 44.1 118.9 5.9 1.8 49.3 13.7 26.0 128.0 18.7 45.1 68.4 26.4 45.6 447.6 41.1 7.3 44.4 92.8 25.7 7.0 21.5 47.8 28.9 3.7 223.8 479.0 30.5 22.4 4.4 9.9 132.3 44.1 6.4 16.0 180.8 5.9 33.4 0.0 444.3 671.8 65.1 74.0 85.4 1.8 30.1 50.7 41.3 24.8 66.9 78.9 64.0 68.4 45.6 57.7 8.0 8.0 1.4 1.3 23.4 34.4 43.1 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.8;Gastric mucus-secreting cells: 23.0;Paneth cells: 18.3;Squamous epithelial cells: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.3;HaCaT: 22.5;MCF7: 30.7;RT4: 18.4;SK-BR-3: 18.4;T-47d: 18.1" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 4.9 0.2 1.4 0.3 2.1 4.8 9.7 1.2 5.4 5.5 8.8 10.6 0.4 2.0 26.5 3.8 2.8 0.4 0.4 0.3 7.7 0.9 7.8 1.3 0.4 0.7 2.2 14.1 6.4 11.0 4.2 1.0 8.5 4.5 0.3 17.7 3.7 0.2 33.7 9.3 0.2 0.3 1.8 12.2 3.3 0.3 2.4 6.0 0.0 2.0 5.8 13.0 0.3 8.9 1.2 0.8 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 11.7 7.5 0.1 4.3 0.0 0.4 22.5 1.3 8.8 0.0 0.4 3.6 0.7 5.3 3.8 0.0 0.3 2.2 0.0 10.9 0.1 0.1 0.1 0.1 3.5 6.1 0.1 0.0 30.7 0.2 1.7 2.7 8.3 1.3 1.3 0.5 4.3 5.5 18.4 15.6 0.7 2.8 18.4 0.5 4.3 18.1 0.4 0.1 0.0 3.1 0.1 0.1 2.1 2.2 2.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 9.7 1.2 0.4 0.3 0.4 0.7 1.0 0.3 0.3 0.3 1.0 9.6 7.9 0.0 1.2 6.5 2.3 3.6 9.6 0.0 5.1 5.8 1.8 2.8 9.6 1.8 0.0 6.4 1.7 14.8 0.0 2.4 0.6 13.2 0.7 0.4 3.6 0.8 0.1 6.2 4.9 0.7 23.0 7.9 1.3 0.4 0.0 0.0 1.0 0.0 0.1 4.8 2.0 0.0 0.4 0.8 0.0 1.3 0.0 0.0 1.2 0.8 1.0 0.0 0.1 2.9 18.3 0.0 0.1 1.6 12.4 0.5 9.5 0.0 0.0 2.2 0.8 1.7 1.3 19.3 8.1 6.7 1.4 0.6 5.7 3.4 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Excitatory neurons: 67.1;Oligodendrocyte precursor cells: 60.8;Pancreatic endocrine cells: 63.8;Proximal tubular cells: 171.1;Sertoli cells: 46.0;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 477.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" 5.0 1.1 3.2 1.4 9.3 0.2 2.6 2.2 3.7 4.3 0.5 1.3 1.3 2.3 1.8 2.4 6.8 9.2 2.0 2.2 7.4 14.8 0.7 4.5 0.6 4.9 9.5 0.7 0.7 1.1 1.0 3.6 6.0 1.1 0.9 1.5 0.7 1.8 1.2 1.0 1.2 2.6 3.2 0.8 1.0 0.3 9.8 0.4 2.3 1.6 0.7 2.3 1.9 3.9 0.1 1.9 62.2 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.2 0.0 0.1 477.1 0.3 0.0 0.0 49.6 0.1 0.0 0.6 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 17.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 9.4 0.0 0.2 0.0 10.9 0.1 14.0 0.0 1.8 0.0 0.0 0.1 0.2 19.3 0.1 0.2 0.0 0.1 1.8 5.9 1.5 0.1 0.4 1.1 0.1 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 9.3 2.2 3.7 2.2 7.4 4.9 9.5 6.0 3.2 9.8 3.9 5.7 0.0 0.5 7.2 2.4 0.9 0.1 36.5 0.0 10.8 0.1 0.4 3.1 48.6 7.0 11.0 0.0 0.0 0.0 0.0 27.4 37.2 0.2 2.9 0.6 5.3 0.0 0.0 67.1 3.0 0.0 2.9 0.0 2.9 0.0 4.1 0.0 0.1 0.1 0.0 33.6 0.0 0.0 0.0 2.5 0.1 0.3 1.3 0.0 39.4 1.0 0.3 0.0 60.8 5.5 63.8 0.0 0.4 0.0 1.2 0.0 171.1 1.1 0.8 46.0 0.6 69.5 0.0 0.4 0.1 1.0 0.0 1.8 0.2 0.0 0.1 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 70.2;Spermatocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 2.5;T-cells: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA018151: AB_1846457, HPA023870: AB_1846459" "unprognostic (7.89e-2)" "unprognostic (1.55e-1)" "unprognostic (5.23e-2)" "unprognostic (3.09e-1)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.06e-1)" "unprognostic (9.86e-2)" "unprognostic (3.04e-1)" "unprognostic (2.04e-2)" "unprognostic (3.34e-3)" "unprognostic (1.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.67e-3)" 19.1 12.0 9.5 19.0 17.7 23.9 14.6 13.6 10.9 18.8 32.0 22.5 28.6 17.8 10.3 12.1 15.9 22.2 14.3 9.8 9.5 25.0 22.9 21.6 25.4 8.6 7.6 14.9 13.9 13.2 21.8 15.0 8.5 20.7 19.3 74.0 15.7 23.1 5.9 10.6 22.1 27.2 5.0 18.7 17.5 62.0 10.5 28.2 49.0 5.6 19.3 29.2 14.0 8.3 38.9 26.8 22.8 24.2 55.2 47.4 23.9 36.4 57.0 36.7 48.4 35.3 25.9 33.3 19.3 62.4 22.2 36.5 49.2 20.8 43.0 26.2 25.1 25.3 29.4 111.0 63.4 27.6 49.6 35.6 18.8 36.2 40.3 46.3 46.2 42.6 25.1 53.3 35.4 28.0 27.8 20.0 32.4 32.3 22.0 40.1 29.4 49.5 45.7 24.8 17.5 12.5 24.8 51.9 36.4 25.7 15.4 13.7 31.9 36.2 22.9 34.5 32.9 27.6 49.7 46.9 23.8 27.1 31.7 8.4 0.8 1.2 1.6 0.7 3.6 0.9 5.3 3.4 0.9 0.6 4.1 3.5 0.7 2.5 0.9 1.1 6.5 1.7 9.5 17.7 13.6 10.9 9.8 9.5 8.6 7.6 8.5 5.0 10.5 8.3 18.2 3.2 5.1 3.6 8.7 34.0 17.3 4.3 15.4 8.9 27.4 9.1 3.5 10.0 7.0 9.2 14.6 1.7 12.7 22.0 1.9 8.7 36.7 6.9 10.0 13.9 6.6 17.2 8.0 7.1 10.8 19.6 19.4 12.0 0.0 9.6 10.0 9.5 9.4 8.4 10.5 16.1 6.1 5.0 11.5 8.8 6.8 7.4 10.6 2.8 4.0 10.1 4.1 3.5 2.2 13.8 12.2 10.9 24.9 19.4 22.4 12.4 4.9 70.2 6.6 9.7 15.8 50.9 16.1 8.7 24.3 1.4 25.8 2.7 7.8 14.8 CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 38: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" 14.3 13.8 30.0 9.1 32.4 13.0 10.6 22.9 28.6 10.5 2.1 13.0 5.2 11.5 8.2 9.2 10.7 8.9 24.8 30.3 34.6 14.6 12.8 13.4 8.8 27.2 36.1 9.3 6.5 17.3 14.4 9.9 37.4 13.4 10.7 31.5 7.6 16.7 9.7 5.9 10.1 18.0 18.8 9.4 10.6 11.7 42.5 13.3 12.5 12.7 12.6 10.8 7.7 21.7 25.4 27.4 28.1 13.7 16.4 14.9 11.7 13.9 28.5 22.7 32.2 17.8 23.8 19.8 6.8 26.4 41.1 36.5 23.1 29.5 23.9 18.4 6.8 23.5 7.9 27.0 15.3 13.9 8.1 12.8 16.1 29.8 11.5 20.3 30.7 26.5 11.6 23.9 21.4 4.6 30.1 5.7 12.1 12.4 7.6 25.0 22.5 9.4 14.5 25.0 11.4 15.5 15.3 26.2 34.6 33.8 16.4 6.7 25.4 15.6 11.6 14.1 14.0 20.8 160.2 15.9 7.4 11.7 8.1 55.3 17.3 21.2 15.2 14.7 16.6 12.1 15.6 17.3 13.8 11.4 12.0 11.8 49.7 12.0 13.4 10.9 19.5 23.7 30.0 32.4 22.9 28.6 30.3 34.6 27.2 36.1 37.4 18.8 42.5 21.7 43.3 19.2 15.7 36.9 36.2 17.6 30.3 33.0 14.2 60.1 17.7 14.4 55.2 18.6 19.6 33.1 95.9 22.2 29.6 15.3 5.9 33.1 71.6 20.1 14.0 42.3 10.7 14.9 39.3 22.7 40.0 17.9 15.3 21.5 21.0 20.5 27.8 21.7 60.8 43.7 52.0 12.4 12.2 36.6 26.1 33.3 16.1 31.5 32.0 21.5 38.7 21.9 28.8 28.6 56.1 31.7 20.3 24.8 48.9 23.1 15.7 13.2 23.5 65.5 19.7 19.7 52.1 26.8 34.7 14.8 15.3 16.3 36.7 13.0 13.1 29.1 CEACAM21 "FLJ13540, R29124_1" ENSG00000007129 "CEA cell adhesion molecule 21" Q3KPI0 19 41549518-41586844 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.5;lymphoid tissue: 10.2" "Cell type enriched" "Detected in some" 10 "Granulosa cells: 150.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 8.6;Karpas-707: 6.1;THP-1: 3.3;U-266/70: 5.8;U-937: 5.8" HPA043411 Uncertain NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA043411: AB_10794886" "unprognostic (2.55e-1)" "unprognostic (1.61e-3)" "unprognostic (5.73e-2)" "prognostic favorable (1.89e-5)" "unprognostic (2.57e-1)" "unprognostic (8.02e-4)" "unprognostic (3.04e-1)" "unprognostic (2.05e-3)" "unprognostic (1.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (3.37e-6)" "unprognostic (2.09e-1)" "unprognostic (3.67e-1)" "unprognostic (1.12e-3)" "unprognostic (1.37e-1)" 1.3 0.7 1.4 2.2 0.8 17.5 0.8 0.8 1.3 2.2 0.6 0.8 0.6 2.6 0.3 0.4 0.7 0.5 0.5 0.8 2.8 0.7 1.2 3.8 5.3 1.9 2.7 0.4 0.2 0.1 0.4 1.5 2.2 0.6 0.6 0.0 0.5 3.6 0.1 0.2 2.6 0.5 1.8 10.2 0.9 1.1 3.9 2.2 0.6 0.1 3.5 0.8 0.3 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 6.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 5.8 1.0 1.0 0.0 5.8 0.0 0.1 6.0 27.3 29.7 11.7 20.1 10.8 25.6 20.8 6.9 15.1 21.3 21.0 30.2 19.2 7.0 12.4 26.6 17.9 1.4 0.8 0.8 1.3 0.8 2.8 1.9 2.7 2.2 1.8 3.9 1.2 1.5 0.0 0.0 0.3 5.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.6 1.8 0.0 0.1 7.2 0.0 0.0 0.0 5.4 7.3 0.1 2.0 0.0 5.7 0.1 0.0 0.1 0.3 0.0 2.2 4.5 150.8 10.0 0.3 9.4 0.0 0.7 0.0 0.0 9.0 0.6 10.3 0.0 6.2 1.8 15.0 1.0 0.0 9.2 0.0 0.1 0.0 0.0 0.4 10.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.6 0.6 0.0 0.0 0.3 8.8 0.0 0.0 0.0 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 94.2;Excitatory neurons: 42.9;Horizontal cells: 75.7;Inhibitory neurons: 45.6;Rod photoreceptor cells: 25.5" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 13.6;Karpas-707: 31.0;SCLC-21H: 54.1;SH-SY5Y: 20.4;U-266/70: 21.1;U-87 MG: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" 0.1 5.5 55.0 1.0 78.8 0.0 0.1 56.9 234.7 0.2 20.0 4.0 0.6 0.9 0.2 0.4 0.1 0.0 1.1 67.4 79.3 1.2 0.3 0.2 0.3 103.8 57.9 0.2 0.2 0.3 26.0 0.0 93.4 3.2 0.1 7.6 0.2 1.5 0.2 0.2 1.4 0.5 21.6 0.3 0.9 0.3 106.3 0.0 0.2 0.0 0.1 0.8 1.1 116.6 0.0 0.7 0.7 1.4 0.2 0.3 0.2 1.3 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.5 13.6 0.5 0.0 0.0 0.0 8.5 0.3 0.0 0.1 0.0 0.1 0.0 5.3 0.6 0.0 0.8 0.0 0.0 0.2 0.0 0.0 31.0 0.5 0.1 0.3 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 54.1 20.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 1.2 0.9 21.1 6.2 1.3 28.6 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 55.0 78.8 56.9 234.7 67.4 79.3 103.8 57.9 93.4 21.6 106.3 116.6 0.1 0.0 0.0 17.6 0.5 0.1 0.1 0.0 0.0 94.2 0.0 0.0 0.5 0.0 0.0 0.0 10.4 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 42.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 75.7 45.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 6.5 0.0 6.7 0.0 15.1 10.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 25.5 0.0 0.1 1.7 0.0 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 CENPX "CENP-X, FAAP10, MGC14480, MHF2, STRA13" ENSG00000169689 "Centromere protein X" A8MT69 17 82018702-82024107 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 172.6;Breast myoepithelial cells: 190.2;Cytotrophoblasts: 197.7;Extravillous trophoblasts: 455.2;Hofbauer cells: 146.1;Pancreatic endocrine cells: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 45: Intestine - Brush border" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (3.11e-1)" "unprognostic (3.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.76e-2)" "unprognostic (2.60e-1)" "unprognostic (2.95e-3)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-3)" "unprognostic (2.74e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.57e-2)" "unprognostic (3.48e-1)" "unprognostic (2.31e-1)" "unprognostic (1.97e-1)" 39.0 29.1 57.8 27.8 58.7 44.3 41.6 62.4 70.6 34.4 54.4 56.3 38.4 26.2 11.6 63.1 29.0 14.9 33.1 56.8 58.2 45.9 89.5 33.4 25.3 58.7 58.9 29.2 33.0 26.2 18.2 30.2 59.6 65.0 30.6 16.2 50.1 18.3 37.7 44.3 40.8 17.1 57.6 29.6 50.3 22.3 60.2 25.4 34.1 21.1 20.7 42.2 38.4 61.0 131.3 352.7 78.4 116.6 30.0 27.6 62.2 91.9 78.1 116.7 79.3 144.1 101.1 47.8 83.9 50.0 113.0 76.1 71.3 88.6 52.7 51.1 259.0 86.0 157.1 247.8 32.2 103.6 61.5 26.8 43.4 90.4 31.6 34.7 111.8 88.4 153.9 75.0 72.7 376.1 174.3 94.3 51.9 329.6 230.9 78.0 84.4 70.9 69.5 157.5 177.5 113.1 51.3 302.0 49.4 38.0 238.1 80.1 40.7 125.0 154.5 215.1 161.3 50.4 27.5 65.6 86.3 84.7 103.2 47.9 112.3 61.5 82.4 99.4 80.6 106.1 79.4 78.7 85.4 83.8 85.3 72.5 24.5 74.4 90.3 105.4 110.7 99.6 57.8 58.7 62.4 70.6 56.8 58.2 58.7 58.9 59.6 57.6 60.2 61.0 61.2 41.7 59.6 0.0 11.3 0.0 0.0 0.0 0.0 0.0 172.6 190.2 0.0 0.0 29.1 44.1 0.0 197.7 33.7 0.0 129.1 102.4 0.0 41.1 34.6 27.6 0.0 0.0 0.0 128.8 455.2 33.4 0.0 49.3 11.4 60.5 0.0 0.0 146.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 51.1 0.0 0.0 0.0 0.0 151.5 0.0 0.0 5.5 0.0 0.0 139.3 17.5 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 105.2 21.8 40.1 0.0 0.0 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" 15.7 23.7 17.5 22.2 18.1 21.1 12.7 33.2 22.5 17.8 16.4 17.9 31.6 17.5 6.0 14.8 18.2 17.4 39.0 18.3 37.4 19.5 18.9 16.6 26.1 32.1 34.5 26.6 30.2 11.5 49.0 10.0 33.2 11.7 14.9 21.1 17.5 13.4 20.8 16.3 31.2 15.2 20.8 19.4 21.9 6.0 26.2 38.7 21.0 19.2 25.2 13.7 12.4 18.4 25.6 15.1 71.6 22.6 40.3 30.2 6.7 43.7 33.8 24.5 17.2 22.3 8.4 35.3 19.9 46.9 15.1 16.3 30.4 19.8 24.9 12.6 33.0 15.8 36.9 29.0 27.9 49.9 4.0 25.3 25.0 26.7 9.1 39.2 73.5 37.1 12.1 44.5 45.4 1.9 34.0 24.8 32.4 10.3 16.3 62.8 81.2 40.4 14.7 0.5 66.4 60.6 21.5 10.3 47.1 16.5 11.3 37.6 67.4 50.2 26.8 37.5 64.4 45.7 59.5 22.3 53.5 28.0 41.7 0.7 3.0 3.7 10.3 7.0 17.9 2.0 10.7 10.0 5.4 2.1 6.3 5.8 4.2 2.6 8.7 5.7 10.4 4.4 17.5 18.1 33.2 22.5 18.3 37.4 32.1 34.5 33.2 20.8 26.2 18.4 28.6 9.6 16.6 16.0 17.0 3.4 6.3 6.1 18.2 24.4 6.1 9.8 44.2 10.0 11.0 1.8 6.2 2.4 25.4 23.4 15.6 12.8 7.8 10.3 19.8 27.4 14.4 8.0 11.7 11.8 1.4 14.1 9.2 19.8 10.1 10.2 25.4 22.1 10.8 26.9 21.9 6.6 8.2 24.8 16.9 16.0 9.6 22.1 3.6 15.9 18.6 25.6 22.6 9.5 4.2 10.9 15.2 15.1 43.3 2.1 50.0 16.8 0.7 9.7 0.0 8.3 13.2 4.7 1.7 11.0 4.4 1.8 37.6 5.3 20.0 1.7 CERKL RP26 ENSG00000188452 "Ceramide kinase like" Q49MI3 2 181536672-181680665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.1;retina: 16.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.8;Endometrial ciliated cells: 43.5;Proximal tubular cells: 13.4;Respiratory ciliated cells: 38.7;Rod photoreceptor cells: 22.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 28 "SCLC-21H: 58.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 14.5" "HPA035443, HPA035444, HPA043203" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA035443: AB_2674625, HPA035444: AB_10672093, HPA043203: " "unprognostic (7.52e-3)" "unprognostic (6.13e-3)" "unprognostic (2.09e-1)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (2.71e-3)" "unprognostic (2.59e-1)" "unprognostic (1.39e-2)" "unprognostic (2.76e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.25e-4)" "unprognostic (4.54e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (3.07e-2)" "unprognostic (8.45e-2)" 1.2 0.5 0.3 0.2 0.6 0.0 1.0 9.7 0.4 3.1 6.0 2.3 0.2 0.8 0.3 0.5 7.8 0.7 0.5 0.8 0.6 8.0 1.3 5.1 0.9 1.8 2.0 0.3 0.7 0.6 0.7 0.1 1.8 1.0 0.3 16.6 1.0 0.2 0.4 0.4 6.8 0.2 1.8 17.1 1.2 0.5 0.4 0.4 0.9 0.3 1.9 1.3 1.2 1.8 0.0 0.8 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.4 0.0 0.3 0.2 0.0 0.3 2.0 0.0 0.4 0.3 0.4 0.0 0.0 0.6 0.5 0.1 0.3 0.6 0.0 0.5 0.9 0.3 0.7 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.8 0.4 0.0 0.4 1.2 0.0 0.0 0.9 0.0 58.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.1 0.8 0.0 0.0 0.3 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 9.7 0.4 0.8 0.6 1.8 2.0 1.8 1.8 0.4 1.8 0.0 3.2 0.5 0.3 0.0 0.0 0.1 1.0 0.0 0.5 0.0 0.0 0.7 1.5 4.9 0.0 18.8 0.0 1.5 0.0 9.8 0.0 4.6 43.5 0.7 0.3 1.8 0.0 6.8 0.0 0.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 2.0 0.0 0.0 2.8 0.0 0.3 0.0 0.0 0.1 2.5 0.0 0.5 0.2 0.0 0.0 0.0 0.4 0.0 2.7 13.4 38.7 22.8 0.0 0.2 0.5 0.4 0.9 0.0 0.0 0.0 0.6 0.0 1.2 0.0 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;choroid plexus: 13.5;fallopian tube: 25.7;testis: 9.4" "Group enriched" "Detected in many" 4 "Early spermatids: 204.5;Late spermatids: 164.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.8" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" 0.0 0.1 2.3 0.0 2.1 0.0 0.1 1.0 1.0 1.3 13.5 0.1 0.0 0.5 1.8 0.0 25.7 0.4 0.0 2.6 2.8 0.4 0.0 2.7 0.0 8.4 12.1 0.0 0.3 0.1 3.5 0.0 6.2 0.1 0.2 9.2 0.1 0.1 0.0 0.0 0.4 0.0 6.1 0.0 0.3 9.4 2.4 0.0 0.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.0 1.0 2.6 2.8 8.4 12.1 6.2 6.1 2.4 3.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.8 7.7 8.8 0.0 4.3 6.8 0.0 12.5 0.0 0.1 1.1 0.0 0.6 204.5 45.1 0.5 0.2 29.1 0.0 0.0 1.5 0.0 0.2 2.0 1.8 0.0 0.2 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.0 0.0 164.3 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.8 0.7 0.0 1.1 1.9 1.1 29.2 19.5 0.0 0.1 0.0 14.4 5.7 0.0 0.0 0.0 0.2 0.1 5.1 0.1 CFAP69 "C7orf63, FAP69, FLJ21062" ENSG00000105792 "Cilia and flagella associated protein 69" A5D8W1 7 90245174-90311063 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Olfaction, Sensory transduction, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 28.4;Endometrial ciliated cells: 55.3;Excitatory neurons: 57.6;Inhibitory neurons: 46.4;Respiratory ciliated cells: 51.7" "Cancer enhanced" "Detected in many" "prostate cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062883 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 39: CACO-2 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA062883: AB_2684893" "unprognostic (7.69e-4)" "unprognostic (9.93e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-2)" "unprognostic (3.13e-3)" "unprognostic (3.12e-2)" "unprognostic (4.11e-1)" "unprognostic (2.83e-1)" "unprognostic (4.51e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-2)" "unprognostic (9.83e-2)" "unprognostic (1.30e-1)" "unprognostic (6.46e-3)" "unprognostic (2.44e-3)" 8.0 3.0 3.5 1.7 3.9 0.0 8.0 3.0 5.1 6.9 20.4 6.0 1.9 4.6 12.5 3.0 14.3 3.1 5.0 3.6 3.8 8.1 6.6 7.4 0.4 7.0 6.7 6.9 4.8 5.1 11.8 0.7 4.8 24.8 2.1 11.9 5.8 3.0 1.9 4.4 3.4 3.4 5.4 3.6 4.5 7.7 4.4 0.1 10.2 0.6 0.7 4.6 3.8 4.5 2.8 1.7 0.2 3.2 3.5 3.6 0.6 0.1 2.5 1.0 1.5 6.0 2.4 0.3 0.1 2.9 3.9 1.0 1.1 1.4 1.7 0.0 1.1 0.0 0.8 1.7 2.0 0.3 0.0 4.1 1.6 4.2 1.5 5.6 1.1 0.3 1.4 0.0 1.8 1.6 0.0 2.6 1.6 0.1 0.8 0.0 0.4 0.0 5.6 0.7 0.6 1.4 2.6 0.3 0.7 0.6 1.0 0.1 0.2 3.2 0.7 3.2 1.1 0.6 0.2 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.9 3.0 5.1 3.6 3.8 7.0 6.7 4.8 5.4 4.4 4.5 1.5 3.2 6.3 28.4 0.2 0.0 1.5 0.0 3.4 4.8 5.5 4.3 3.0 8.6 6.8 5.5 18.8 0.2 0.0 0.9 1.9 1.9 24.1 55.3 5.6 1.0 0.0 0.8 57.6 1.6 0.1 9.1 2.6 3.4 0.0 4.2 1.1 1.6 0.1 8.4 46.4 0.8 0.0 0.3 0.0 6.2 1.2 0.4 0.0 12.2 0.0 4.2 0.0 13.0 8.2 0.6 1.0 2.2 0.0 7.0 1.9 3.7 51.7 18.2 0.0 9.5 3.8 22.7 1.8 1.5 0.0 0.1 0.1 4.9 1.1 1.4 CFAP74 "C1orf222, FLJ45476, KIAA1751" ENSG00000142609 "Cilia and flagella associated protein 74" Q9C0B2 1 1921951-2003837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.1;testis: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 11.5;Endometrial ciliated cells: 36.0;Excitatory neurons: 11.6;Late spermatids: 20.3;Respiratory ciliated cells: 18.2;Spermatocytes: 16.4;Spermatogonia: 10.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028521, HPA029274, HPA030240" Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "HPA028521: AB_10601881, HPA029274: AB_10601997, HPA030240: AB_2732455" "unprognostic (5.41e-3)" "unprognostic (1.53e-1)" "unprognostic (3.02e-1)" "unprognostic (9.12e-3)" "unprognostic (3.95e-2)" "unprognostic (2.21e-1)" "unprognostic (2.21e-2)" "unprognostic (1.81e-1)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.47e-1)" "unprognostic (1.26e-6)" "unprognostic (1.28e-1)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" 0.2 1.3 0.1 0.4 0.3 0.9 0.2 2.8 1.3 0.4 2.9 0.2 0.3 0.5 0.2 0.9 7.1 0.7 0.2 0.9 0.3 0.1 0.6 1.4 0.7 1.4 2.5 0.2 0.0 0.1 0.5 0.3 1.1 0.2 0.2 0.8 0.4 0.4 0.8 3.2 0.1 0.1 0.2 0.3 0.2 5.2 0.8 0.1 1.1 0.0 0.1 0.3 0.0 2.1 0.7 0.0 0.9 0.7 0.0 0.9 1.0 0.1 0.0 0.0 0.4 1.7 0.1 1.0 1.4 0.3 0.7 0.2 0.0 0.3 0.2 0.9 1.4 2.1 2.6 1.1 0.3 1.6 0.6 0.7 1.0 0.0 0.0 0.4 0.0 0.7 3.0 0.5 0.5 0.3 0.8 0.3 0.9 0.1 1.2 0.8 0.3 0.5 0.0 1.4 1.5 0.5 0.3 0.1 0.0 0.3 0.3 0.4 1.7 0.9 0.9 0.4 1.1 1.0 0.4 1.1 0.1 1.6 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.3 2.8 1.3 0.9 0.3 1.4 2.5 1.1 0.2 0.8 2.1 0.2 0.0 1.8 0.7 0.1 0.0 1.0 0.0 0.0 1.5 0.2 0.4 1.9 0.0 4.3 0.0 8.4 1.1 0.2 0.0 0.0 0.0 11.5 36.0 0.4 0.6 0.0 0.0 11.6 0.0 3.3 0.9 0.0 0.7 0.0 0.3 3.6 1.0 0.1 0.0 5.9 0.0 0.0 1.0 0.0 20.3 1.2 0.6 0.0 9.4 0.0 0.3 1.0 1.0 1.0 0.0 0.0 0.0 0.0 1.1 1.6 0.2 18.2 2.4 0.0 1.5 1.1 16.4 10.1 0.0 0.0 0.8 0.7 0.8 0.1 0.5 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.6;Breast myoepithelial cells: 2.4;Distal enterocytes: 3.3;Gastric mucus-secreting cells: 4.6;Hepatocytes: 2.4;Intestinal goblet cells: 4.3;Oligodendrocyte precursor cells: 5.5;Paneth cells: 2.5;Proximal enterocytes: 2.6" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Cell line enhanced" "Detected in some" "RT4: 4.0;SCLC-21H: 8.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" 2.1 14.1 6.2 0.7 7.9 0.3 9.6 17.4 7.3 21.8 3.9 6.7 7.6 0.5 0.1 1.8 0.8 1.5 1.7 5.5 6.3 2.4 36.2 1.6 0.6 5.6 4.9 3.1 32.6 0.0 1.3 0.5 5.7 1.9 4.0 0.5 21.3 0.2 14.5 8.5 10.3 0.1 5.1 1.1 10.8 1.2 5.8 0.2 4.2 0.9 0.2 1.2 1.6 5.4 1.0 0.8 0.7 0.6 0.0 0.0 2.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.6 0.7 1.2 0.7 1.5 0.0 0.4 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.1 0.7 0.9 0.1 1.5 0.0 4.0 8.5 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.9 2.1 0.4 0.1 0.0 1.4 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 6.2 7.9 17.4 7.3 5.5 6.3 5.6 4.9 5.7 5.1 5.8 5.4 0.0 0.0 0.0 1.3 1.0 0.3 0.2 0.3 0.0 0.0 4.6 2.4 0.2 1.5 0.2 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.2 4.3 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.5 0.1 0.0 2.5 0.0 1.1 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.4 CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 772.6" "Cell type enhanced" "Detected in many" "Astrocytes: 195.2;Excitatory neurons: 596.4;Inhibitory neurons: 111.7;Microglial cells: 97.4;Oligodendrocyte precursor cells: 149.8" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.5;memory CD8 T-cell: 2.1;T-reg: 8.0" "Lineage enriched" "Detected in single" 18 "T-cells: 8.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" 11.8 13.3 368.6 7.3 445.9 0.8 10.5 194.0 772.6 9.2 170.6 10.2 3.3 7.9 38.3 6.9 6.5 11.1 15.1 492.6 241.5 4.7 2.1 19.6 21.5 210.2 225.4 5.8 4.2 43.4 36.3 38.6 210.5 17.0 5.1 39.5 3.2 9.6 2.7 3.8 7.5 13.1 192.4 5.5 7.1 21.3 239.1 3.1 10.2 3.7 18.7 8.7 6.7 422.8 0.4 17.4 57.6 16.3 14.7 67.4 0.4 45.6 186.7 65.1 97.0 0.3 5.4 0.5 1.6 71.8 39.9 2.0 68.0 1.9 30.3 1.3 32.9 11.1 20.1 3.8 34.4 6.4 1.7 53.6 1.9 31.6 11.1 16.1 33.6 30.0 0.7 1.9 57.2 11.8 29.3 2.5 71.7 2.6 23.7 8.2 70.3 0.8 0.9 0.6 71.3 76.3 41.3 0.5 7.3 36.0 3.2 2.2 10.1 26.8 3.9 9.8 20.6 6.4 33.7 0.7 6.7 0.4 6.6 0.4 0.1 0.1 0.3 0.1 0.8 0.2 6.5 2.1 0.0 0.1 1.3 0.4 0.4 0.2 0.2 0.3 8.0 1.0 368.6 445.9 194.0 772.6 492.6 241.5 210.2 225.4 210.5 192.4 239.1 422.8 15.4 3.2 1.9 195.2 1.6 4.5 0.3 0.0 0.0 85.1 7.3 1.4 6.2 1.5 2.6 3.7 27.1 1.2 0.5 0.1 0.0 0.3 24.1 5.3 5.6 17.9 2.4 0.0 596.4 0.6 1.1 28.4 2.0 3.6 0.0 5.1 10.4 0.5 2.7 77.4 111.7 0.0 0.0 0.0 4.0 23.2 3.1 0.9 7.2 97.4 0.0 59.1 0.0 149.8 88.1 0.6 0.0 5.3 1.3 0.6 0.0 0.3 1.0 14.1 13.1 23.8 27.3 17.8 23.6 0.1 3.7 2.1 12.5 5.1 0.2 0.3 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 194.1;Hepatocytes: 112.2;Skeletal myocytes: 533.4" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;PC-3: 1.3;SiHa: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" 2.7 0.2 0.6 115.8 0.4 0.0 5.1 0.4 0.7 64.7 0.1 88.7 4.1 145.1 0.8 4.1 9.4 106.0 24.4 0.4 0.6 5.2 46.3 2.9 0.4 1.0 0.6 2.5 3.1 0.4 0.4 4.5 0.7 22.6 2.6 0.5 0.5 8.9 6.6 1.2 10.8 122.1 2.3 1.3 57.7 3.4 0.7 0.0 0.9 4.8 2.8 46.3 21.2 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.4 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.4 0.7 0.4 0.6 1.0 0.6 0.7 2.3 0.7 0.2 1.2 0.0 2.6 0.7 0.3 0.3 0.5 0.2 0.0 0.0 194.1 3.8 2.2 15.7 0.1 9.2 0.0 0.0 0.8 0.0 0.0 13.8 31.4 0.6 0.2 2.1 0.0 0.0 0.1 10.3 0.1 5.3 0.0 0.5 0.0 0.2 2.9 112.2 0.1 0.0 0.2 0.0 0.0 2.4 0.0 2.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 4.1 0.0 0.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 533.4 1.2 0.6 4.3 0.0 0.0 0.1 0.5 0.4 0.0 0.5 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Breast myoepithelial cells: 3.6;Excitatory neurons: 8.7;Inhibitory neurons: 7.8;Intestinal goblet cells: 3.2;Melanocytes: 3.6;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 4.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 3.7;OE19: 12.3" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.0 3.3 12.4 0.3 18.7 0.0 2.7 0.0 27.0 0.0 0.0 0.8 0.4 0.1 0.0 0.3 0.2 0.1 0.1 22.6 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.0 29.6 0.7 0.1 28.8 0.0 0.0 2.8 0.7 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 12.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.4 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 18.7 0.0 27.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 1.8 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 3.2 0.0 0.0 0.3 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 3.0 1.0 0.0 0.1 0.0 0.0 4.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.1 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470984-40473158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.5;Extravillous trophoblasts: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved "Golgi apparatus" NA NA 20000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "HPA057697: AB_2683505, HPA071601: AB_2686425" "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" 14.2 9.6 6.8 7.7 7.5 3.4 13.7 7.0 6.5 22.0 7.3 11.8 4.5 21.6 8.0 8.7 16.5 11.3 13.8 6.2 7.0 10.1 8.8 13.0 8.5 8.0 7.1 21.1 8.1 11.3 14.4 27.0 7.2 14.6 4.6 1.6 11.0 15.4 5.0 9.1 9.9 12.6 7.5 13.6 9.4 7.9 7.0 8.6 15.8 7.4 7.5 16.1 16.1 7.3 26.2 17.1 26.4 71.6 40.4 31.0 43.0 25.2 47.3 43.5 40.9 21.2 12.8 4.3 37.6 42.7 76.7 43.7 23.7 14.2 20.3 31.5 15.0 13.4 16.9 19.8 22.5 5.7 33.4 38.3 11.6 15.4 11.6 47.8 39.2 15.1 13.6 15.0 32.6 20.1 9.6 29.8 17.0 7.9 20.1 26.2 33.4 7.6 29.5 13.3 19.7 30.2 22.2 24.4 8.4 31.9 35.7 23.9 31.9 73.0 27.1 23.3 25.5 30.3 22.6 12.2 32.8 19.6 53.7 7.6 1.1 2.2 2.2 1.1 0.6 0.3 1.1 1.9 2.0 1.1 0.9 0.8 0.1 3.3 0.6 0.7 0.8 0.7 6.8 7.5 7.0 6.5 6.2 7.0 8.0 7.1 7.2 7.5 7.0 7.3 10.6 12.8 1.1 2.0 5.8 3.4 5.4 4.1 9.1 0.6 5.8 9.7 3.2 7.2 4.6 3.7 0.0 46.5 3.5 0.5 0.0 7.7 1.8 3.2 14.5 10.2 2.4 10.7 0.1 4.9 32.4 19.3 0.0 5.6 4.5 14.9 15.4 3.7 9.3 1.7 0.1 1.4 2.0 5.6 3.3 1.3 17.7 5.6 5.4 2.8 3.4 9.8 6.2 2.0 0.5 5.2 0.3 11.7 1.9 3.6 0.2 1.1 3.0 0.8 6.6 11.8 9.2 7.5 1.3 5.6 2.6 13.5 4.9 3.9 1.9 1.3 CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.3" "Cell type enhanced" "Detected in many" "B-cells: 48.8;Langerhans cells: 51.8;Macrophages: 43.8;Microglial cells: 42.2;monocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 29.1;eosinophil: 17.5;intermediate monocyte: 23.5;memory B-cell: 47.3;myeloid DC: 46.2;naive B-cell: 63.3;non-classical monocyte: 29.0;plasmacytoid DC: 48.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 51.1;REH: 89.5;U-266/70: 18.0;U-698: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" 9.4 6.5 6.4 39.2 5.9 9.2 7.8 7.3 7.9 10.7 8.9 6.7 20.5 7.3 2.6 5.5 7.4 15.0 5.4 5.4 11.5 7.2 4.7 24.1 57.3 15.0 8.3 3.6 3.9 2.6 3.0 2.6 11.9 4.8 8.2 1.4 12.1 6.9 5.0 8.7 24.8 7.3 11.5 51.2 12.9 2.1 13.0 15.9 5.2 2.4 57.0 9.0 4.1 16.4 0.4 0.4 0.7 0.6 0.1 0.0 0.5 0.2 0.0 0.3 0.4 0.6 12.0 11.2 1.6 0.0 1.7 1.8 0.0 0.0 0.2 51.1 0.6 6.3 2.6 1.3 0.0 0.9 0.9 2.1 0.0 0.2 0.0 1.8 0.0 0.7 0.8 4.1 0.2 0.7 0.6 1.0 0.3 0.4 0.3 89.5 0.6 7.9 0.1 3.6 1.8 0.3 2.1 0.6 2.1 0.6 1.0 3.8 0.5 4.3 0.7 1.2 0.5 18.0 1.4 25.8 16.0 1.1 14.7 0.7 29.1 17.5 0.8 23.5 0.4 47.3 0.3 1.4 46.2 63.3 0.2 0.4 6.8 1.8 29.0 48.3 1.2 5.4 6.4 5.9 7.3 7.9 5.4 11.5 15.0 8.3 11.9 11.5 13.0 16.4 14.5 6.4 19.5 0.3 48.8 2.3 0.3 1.3 1.2 0.8 1.7 2.0 5.3 1.5 1.5 3.7 0.0 0.2 17.9 2.0 0.0 5.5 0.8 1.5 0.4 7.3 2.4 6.9 1.4 2.0 0.3 1.2 4.6 1.4 10.8 7.7 1.4 0.7 8.7 0.0 1.8 1.9 0.0 16.1 51.8 0.0 0.6 43.8 7.2 42.2 51.8 0.2 2.1 0.0 0.3 1.1 0.1 0.0 1.1 0.4 12.3 4.8 5.6 1.6 0.0 1.0 1.2 0.0 0.0 1.0 2.8 0.1 3.0 0.4 1.5 0.5 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 373.9;intestine: 257.8" "Group enriched" "Detected in many" 6 "Distal enterocytes: 597.0;Paneth cells: 183.2;Squamous epithelial cells: 158.7;Urothelial cells: 176.9" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 1368 "RT4: 430.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" NA NA 150000 "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" 0.6 0.0 6.3 13.9 9.4 0.0 2.2 6.7 8.0 44.6 3.2 257.8 0.1 0.1 0.1 373.9 0.2 0.2 0.1 6.2 6.6 0.1 0.1 0.0 0.0 10.9 7.0 0.0 0.1 0.0 0.5 0.0 8.7 2.5 143.5 0.0 23.1 0.2 0.1 17.1 29.1 2.9 7.1 0.1 0.6 0.3 8.0 0.1 0.0 0.0 30.1 99.3 66.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 430.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.4 6.7 8.0 6.2 6.6 10.9 7.0 8.7 7.1 8.0 12.7 0.1 0.0 0.0 0.0 2.9 3.3 40.3 6.5 2.8 0.0 1.9 1.8 0.4 0.0 17.5 1.8 0.0 0.0 0.2 597.0 0.0 0.0 0.4 7.3 0.1 0.3 8.3 0.0 0.1 0.0 0.0 0.4 0.0 3.5 8.9 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 183.2 0.0 1.2 9.7 4.7 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 158.7 11.9 0.0 1.5 0.0 12.0 176.9 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLEC17A FLJ45910 ENSG00000187912 "C-type lectin domain containing 17A" Q6ZS10 19 14583084-14612035 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 18.2" "Group enriched" "Detected in some" 4 "B-cells: 20.7;Early spermatids: 5.3;Late spermatids: 12.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "memory B-cell: 21.5;naive B-cell: 43.1" "Lineage enriched" "Detected in many" 14 "B-cells: 43.1" "Group enriched" "Detected in some" 5 "Daudi: 5.7;U-698: 9.9" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.71e-5)" "unprognostic (1.34e-2)" "unprognostic (9.64e-4)" "unprognostic (5.02e-3)" "unprognostic (3.90e-1)" "unprognostic (9.00e-4)" "unprognostic (3.18e-3)" "unprognostic (1.60e-3)" "unprognostic (1.32e-2)" "unprognostic (7.11e-2)" "unprognostic (3.78e-2)" "unprognostic (4.43e-2)" "unprognostic (9.13e-3)" "unprognostic (1.65e-1)" "unprognostic (5.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" 0.3 0.2 0.7 8.2 0.7 2.2 0.1 1.6 0.9 0.0 0.9 0.5 0.5 0.3 0.2 0.2 0.2 0.6 0.2 0.7 0.9 0.2 0.2 0.2 16.1 1.3 0.9 0.2 0.0 0.1 0.1 0.2 1.2 0.3 0.6 0.4 0.6 0.1 0.3 0.5 6.6 0.1 0.9 11.4 0.7 0.9 0.8 1.4 0.2 0.1 18.2 0.9 0.0 1.5 0.1 0.0 0.1 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.2 1.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.4 0.0 0.2 0.1 1.4 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.3 0.1 9.9 0.3 0.1 0.1 0.7 0.7 0.3 0.2 0.4 0.2 21.5 0.1 0.1 3.0 43.1 0.2 0.2 2.7 0.4 0.3 0.5 0.1 2.2 0.7 0.7 1.6 0.9 0.7 0.9 1.3 0.9 1.2 0.9 0.8 1.5 0.0 0.0 0.0 1.3 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.7 0.0 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 222.1;Granulosa cells: 140.8;Hofbauer cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" 49.3 16.6 15.5 25.0 14.3 20.0 32.8 15.6 28.1 40.2 9.5 16.8 7.1 30.4 16.6 10.4 25.5 32.7 26.2 15.6 18.0 19.7 10.7 35.4 32.3 24.9 15.8 38.9 7.9 29.4 10.1 44.4 19.3 23.4 12.1 3.0 17.4 16.7 6.4 22.2 18.8 27.7 17.0 36.1 11.9 59.7 19.1 35.5 16.1 13.0 20.9 34.3 26.7 20.4 6.7 33.8 93.4 66.2 68.4 42.6 59.2 17.5 78.6 34.4 34.0 18.6 21.0 0.2 47.7 49.0 59.7 7.8 63.7 57.4 27.3 34.6 23.2 21.5 4.4 53.5 92.2 65.8 77.4 85.5 4.5 36.6 7.7 141.3 78.9 59.5 34.6 0.7 42.8 7.8 53.1 108.9 45.0 0.5 31.8 164.7 65.6 3.3 16.4 0.8 9.9 33.9 8.5 0.3 58.5 59.9 0.7 59.3 54.0 48.7 58.8 12.0 21.1 4.4 0.7 21.8 30.5 50.0 53.7 7.9 14.2 9.9 9.2 13.9 12.9 2.6 10.3 10.5 12.3 0.9 8.0 9.8 8.0 8.6 8.9 24.9 15.7 5.8 15.5 14.3 15.6 28.1 15.6 18.0 24.9 15.8 19.3 17.0 19.1 20.4 38.0 0.0 7.1 0.3 12.9 14.7 33.5 10.0 6.8 0.5 12.3 25.7 2.0 4.3 6.4 5.5 0.0 10.7 101.2 0.4 0.0 28.1 2.8 4.9 56.0 50.4 12.5 12.8 0.6 6.4 222.1 62.6 2.6 6.2 91.3 140.8 44.3 1.3 119.8 0.0 0.3 0.7 8.2 74.7 77.9 9.4 39.4 78.0 28.4 10.3 61.5 10.0 82.4 8.0 0.2 41.0 0.1 24.5 5.7 40.8 0.1 4.4 3.1 0.8 6.6 26.3 36.1 4.9 8.1 1.1 8.7 9.4 68.9 10.5 0.2 21.6 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 334.7;Proximal enterocytes: 629.1;Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 458.7;RPMI-8226: 616.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 54.8 40.7 125.3 75.0 147.0 25.1 60.4 139.4 156.9 136.8 113.0 83.6 190.1 44.2 122.8 78.4 140.8 94.4 63.7 123.7 133.2 327.3 261.1 82.3 86.3 143.1 137.4 34.4 100.7 58.5 48.0 75.4 144.7 122.5 79.5 42.1 57.4 101.7 26.6 47.0 255.0 37.9 140.4 137.0 103.5 20.9 143.9 52.5 159.1 22.4 82.2 94.5 47.4 157.6 64.6 85.0 60.5 57.4 72.2 42.5 252.3 66.0 61.7 88.3 87.4 49.6 67.1 80.3 81.4 72.1 69.0 95.0 92.7 124.9 62.7 121.3 36.7 80.2 42.1 79.6 104.6 158.7 119.3 64.5 93.9 76.4 136.6 50.1 78.3 94.6 86.3 458.7 59.1 71.6 84.9 75.6 91.0 42.4 50.3 91.3 69.4 616.6 346.1 264.1 65.3 34.2 51.6 360.2 91.6 143.0 151.5 64.0 82.5 93.9 79.5 21.2 45.2 85.5 380.6 108.1 63.6 113.8 80.2 37.1 115.4 49.0 77.6 166.3 84.4 102.4 61.6 72.2 185.1 110.5 65.5 72.4 15.9 124.6 174.1 161.3 94.5 135.7 125.3 147.0 139.4 156.9 123.7 133.2 143.1 137.4 144.7 140.4 143.9 157.6 39.2 73.7 62.7 16.6 55.7 9.2 40.3 48.6 12.5 33.6 76.5 36.4 26.9 77.2 56.8 119.5 16.7 157.9 47.8 99.0 187.9 168.1 3.3 187.7 49.7 49.6 65.3 23.3 8.8 154.7 130.9 23.5 63.7 334.7 12.0 34.0 40.0 119.8 216.3 43.7 10.8 82.9 75.3 122.9 24.9 4.1 18.6 79.0 17.8 13.1 90.8 86.6 55.6 15.6 51.7 108.9 103.5 16.6 44.4 65.2 629.1 487.6 73.3 31.6 13.1 15.2 22.3 8.3 7.2 27.1 9.7 109.0 38.2 32.8 99.8 53.8 CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 18.6;BEWO: 16.0;CAPAN-2: 29.1;HaCaT: 20.3;hTCEpi: 17.2;OE19: 15.9;SK-BR-3: 20.8;T-47d: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA030847: AB_10601100" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-2)" "unprognostic (5.26e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-1)" "unprognostic (2.49e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-2)" "unprognostic (3.27e-2)" "unprognostic (2.91e-1)" "prognostic favorable (5.91e-4)" 0.7 0.1 3.6 2.6 4.1 0.3 6.0 5.3 4.7 6.6 2.2 9.4 11.9 2.5 8.2 18.7 8.2 3.6 1.4 3.6 3.7 9.5 1.6 7.3 1.4 4.0 3.6 3.2 13.4 11.7 9.6 4.7 3.8 10.3 7.4 0.9 15.6 6.6 57.2 16.6 11.4 0.7 3.2 2.4 10.5 2.4 3.8 1.1 16.7 14.3 2.9 5.5 9.0 4.9 18.6 0.0 0.3 0.2 0.3 0.0 16.0 0.3 0.0 0.2 0.0 2.9 29.1 2.0 9.1 0.0 0.2 20.3 0.5 13.0 0.4 0.0 0.9 0.4 7.4 9.2 0.1 0.2 0.3 0.0 17.2 0.0 5.0 0.0 0.0 0.6 2.2 0.1 0.0 8.4 0.2 1.5 7.7 15.9 1.7 0.2 0.2 0.0 1.9 10.7 3.5 0.9 0.1 20.8 0.3 6.9 16.7 0.0 0.0 0.0 2.4 1.0 0.2 5.8 1.1 0.7 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.8 0.1 3.6 4.1 5.3 4.7 3.6 3.7 4.0 3.6 3.8 3.2 3.8 4.9 1.6 16.0 7.2 3.6 3.1 14.7 16.9 36.6 17.6 2.8 22.9 20.2 1.1 17.2 21.2 35.0 2.1 34.2 0.5 26.7 1.9 12.3 1.1 15.9 2.8 1.9 18.6 0.0 3.3 12.4 13.7 1.3 34.7 25.9 0.0 1.8 0.7 0.2 2.8 0.0 3.7 20.0 28.5 0.0 1.2 0.8 1.2 0.8 1.8 0.0 1.4 0.7 0.0 0.5 5.1 25.0 29.9 0.7 14.3 15.7 28.4 0.5 33.1 2.9 0.0 3.6 3.3 2.4 4.2 20.2 11.4 32.4 1.1 0.1 20.0 26.6 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.2;Erythroid cells: 116.2;granulocytes: 122.9" "Cancer enhanced" "Detected in all" "glioma: 14.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.2" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.2" "Cell line enhanced" "Detected in many" "HEL: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 54000 "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA035337: AB_10601359" "unprognostic (1.23e-1)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (6.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.86e-2)" "unprognostic (4.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.04e-2)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.38e-3)" 27.4 6.4 59.0 5.9 62.3 6.1 20.2 50.9 71.6 30.1 29.6 17.1 3.5 22.4 6.1 5.3 24.2 8.5 16.0 65.1 51.8 10.3 2.9 18.3 5.1 40.4 45.1 31.2 3.0 1.8 15.4 12.1 44.3 15.1 4.6 29.6 5.8 8.9 6.6 8.1 10.9 9.3 44.7 10.2 10.6 2.6 52.7 2.7 8.9 7.0 2.9 20.7 19.2 51.8 0.0 1.1 9.0 0.0 34.1 24.6 0.1 34.5 26.6 30.6 22.3 0.0 0.0 0.0 1.2 33.2 22.6 0.0 0.7 0.2 32.6 0.0 8.1 158.7 2.3 0.0 34.7 0.1 21.7 22.1 0.0 20.0 11.5 18.7 47.8 0.0 0.2 0.1 23.4 0.1 0.0 0.4 16.3 0.0 15.6 0.0 13.2 0.0 0.0 0.0 45.8 47.8 2.2 0.0 28.3 0.1 0.0 1.7 51.4 21.1 12.9 18.5 51.0 0.0 0.0 0.1 16.9 0.0 15.5 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 59.0 62.3 50.9 71.6 65.1 51.8 40.4 45.1 44.3 44.7 52.7 51.8 50.2 0.0 4.3 15.0 0.6 12.9 0.4 0.0 4.6 72.2 0.6 1.7 2.1 0.0 0.6 0.0 22.9 1.2 0.1 0.0 0.0 0.4 0.7 1.9 30.4 60.6 0.0 116.2 48.8 0.2 9.3 44.4 0.5 0.6 122.9 1.3 36.4 0.8 56.3 28.6 39.5 0.0 0.0 25.7 40.9 2.6 45.4 13.9 37.4 16.9 2.5 42.0 0.0 24.1 19.6 0.5 0.0 42.5 0.5 1.2 0.0 0.1 0.0 54.3 46.0 18.7 41.9 0.7 0.5 0.7 10.7 2.1 3.8 27.3 0.0 1.0 CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Fibroblasts: 22.4;Muller glia cells: 83.6;Paneth cells: 30.6" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 109.3;SH-SY5Y: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" 60.0 10.3 67.2 1.3 91.9 0.0 49.7 81.5 69.0 29.7 16.3 7.6 3.3 2.8 2.6 3.9 13.0 6.3 39.0 54.3 58.5 2.9 12.4 3.8 1.0 57.0 82.8 5.2 2.2 0.2 9.7 5.2 62.2 11.0 2.2 13.9 11.3 7.7 129.7 11.5 8.7 0.7 49.8 30.6 7.0 7.2 94.1 5.1 13.7 35.1 0.4 5.6 17.1 47.4 0.0 0.0 109.3 0.0 13.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 52.1 0.1 0.1 0.0 1.0 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.2 91.9 81.5 69.0 54.3 58.5 57.0 82.8 62.2 49.8 94.1 47.4 0.9 0.0 0.0 57.1 0.0 3.6 1.1 0.0 1.2 19.3 11.9 1.5 1.3 8.6 0.0 0.0 6.2 0.9 0.1 6.5 1.9 0.1 4.3 0.1 2.4 0.3 0.0 0.0 4.1 0.0 0.6 22.4 0.0 0.1 0.0 0.0 2.5 1.4 1.4 3.3 9.3 0.5 0.0 0.0 2.7 1.9 9.9 0.1 3.6 2.8 0.0 83.6 0.0 15.1 0.5 0.0 30.6 2.2 0.3 0.2 14.1 0.1 0.0 3.2 0.0 1.2 1.9 5.5 19.8 0.3 2.4 2.3 0.2 0.0 0.5 0.3 CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Spermatocytes: 84.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cell line enhanced" "Detected in many" "HEL: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" 4.4 2.4 2.3 2.1 2.4 7.3 3.5 7.7 2.2 5.0 3.3 4.5 1.2 7.1 2.4 2.7 4.3 4.2 2.3 1.7 2.6 2.4 10.5 2.8 2.7 2.7 3.1 8.8 1.7 4.4 2.2 3.6 3.0 2.7 2.2 2.1 1.6 3.2 1.6 1.9 2.2 4.5 2.6 3.9 1.9 5.2 2.5 2.8 3.1 2.5 1.6 3.5 3.5 2.8 8.3 5.6 12.1 6.8 5.8 13.6 0.4 9.5 6.3 7.0 9.5 0.4 2.7 6.0 1.5 6.6 7.5 0.3 14.1 3.9 10.9 0.3 4.9 35.5 11.7 2.0 6.4 4.9 7.4 8.6 2.0 5.8 5.7 6.5 10.0 2.2 1.3 1.1 11.3 0.6 4.0 7.8 9.4 1.4 10.3 5.8 11.2 3.0 4.1 2.0 7.6 7.9 11.6 0.2 3.0 4.8 2.3 12.3 7.5 9.5 3.7 10.4 8.3 4.7 6.1 0.1 4.4 6.1 4.4 0.2 1.3 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.1 0.5 3.9 0.7 0.1 0.2 2.3 2.4 7.7 2.2 1.7 2.6 2.7 3.1 3.0 2.6 2.5 2.8 32.0 6.4 17.6 59.7 1.6 8.8 13.7 6.1 13.1 12.3 3.6 5.8 13.4 7.2 3.4 9.2 0.0 2.5 1.1 2.4 5.9 10.1 16.3 23.4 30.7 24.9 2.4 17.1 20.3 12.0 5.2 29.2 4.1 17.0 7.6 42.4 20.0 38.8 18.4 20.2 37.2 5.9 4.1 40.3 11.6 8.8 45.7 24.0 8.8 91.8 31.0 21.4 1.0 70.4 29.6 4.0 0.8 30.9 1.8 3.8 5.3 8.5 6.7 8.1 13.1 34.2 21.3 84.3 48.9 5.3 5.5 1.0 1.7 31.6 5.5 6.3 CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 763.9;Excitatory neurons: 844.8;Inhibitory neurons: 699.0;Oligodendrocyte precursor cells: 1021.4" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 224.4;HaCaT: 40.3;SCLC-21H: 68.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" 3.9 33.2 64.0 2.5 75.3 0.2 8.8 119.4 84.2 14.1 0.0 3.1 1.7 11.5 2.6 9.1 2.2 11.7 0.8 93.6 59.8 12.4 1.2 4.4 4.5 72.6 94.7 49.2 6.0 1.4 10.4 0.3 70.0 27.8 3.8 26.8 5.4 27.7 0.8 12.8 3.0 10.6 129.0 8.2 5.0 9.4 79.2 1.0 1.2 1.6 3.9 21.5 6.6 158.2 0.1 224.4 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.0 40.3 6.0 11.2 0.0 0.2 2.4 0.0 0.7 0.0 0.0 0.0 0.7 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.2 1.5 0.2 0.1 0.0 1.0 0.3 0.0 0.0 68.5 40.3 0.1 2.5 2.7 1.0 0.1 0.6 0.0 0.1 4.3 0.1 10.0 2.8 0.1 0.0 0.3 0.0 0.9 2.6 0.5 0.7 0.3 0.2 0.3 0.4 0.2 0.2 0.1 0.4 0.4 0.2 1.2 0.7 0.4 0.9 0.2 0.0 64.0 75.3 119.4 84.2 93.6 59.8 72.6 94.7 70.0 129.0 79.2 158.2 0.3 0.0 5.9 763.9 0.1 5.2 1.1 1.6 4.0 32.1 0.4 1.8 0.7 0.0 4.5 5.5 29.2 0.0 0.0 0.0 1.9 0.0 34.9 4.3 7.1 0.7 0.0 0.0 844.8 0.0 0.0 13.3 0.0 0.3 0.0 5.0 0.0 0.0 0.1 11.8 699.0 0.0 2.0 0.0 4.0 149.5 62.7 0.1 10.6 54.4 0.0 34.6 0.0 1021.4 23.9 0.7 0.0 60.2 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.5 3.6 0.6 0.8 2.1 13.5 0.0 0.5 0.3 0.0 0.2 CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 411.7;Excitatory neurons: 960.7;Inhibitory neurons: 1048.5;Oligodendrocyte precursor cells: 248.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 8.3;CACO-2: 9.0;HEK 293: 5.5;SH-SY5Y: 16.5;WM-115: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 170000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" 3.4 0.5 2.2 1.1 6.4 0.0 2.5 13.5 12.3 8.7 0.0 4.6 1.8 8.3 1.9 3.1 4.2 5.1 2.5 1.8 2.7 4.2 2.9 2.4 1.1 0.5 5.4 1.0 1.6 22.6 1.9 7.9 1.2 4.3 3.3 19.8 0.9 5.6 0.7 0.7 4.1 4.5 4.2 1.0 3.6 13.4 7.7 2.2 10.3 4.0 2.6 3.6 1.7 4.0 0.0 0.0 1.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 16.5 0.0 0.0 0.1 1.2 0.1 0.2 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 6.4 13.5 12.3 1.8 2.7 0.5 5.4 1.2 4.2 7.7 4.0 0.4 9.6 3.6 26.8 0.1 0.8 1.3 0.0 1.8 96.5 2.0 1.8 1.4 7.2 5.6 0.0 0.0 0.1 0.0 1.8 0.0 4.4 411.7 0.3 9.1 1.9 7.8 0.0 960.7 0.0 0.1 18.1 0.0 0.3 0.0 6.9 0.7 0.4 0.3 101.0 1048.5 2.0 0.0 0.3 0.7 156.3 5.0 0.4 1.8 31.9 0.0 27.5 0.0 248.3 14.7 0.0 1.6 5.3 0.4 0.4 3.7 3.7 0.0 5.9 6.6 0.5 8.3 4.5 4.9 0.9 0.0 0.3 0.1 0.1 3.5 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 50.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.5;Excitatory neurons: 79.9;Inhibitory neurons: 71.5;Late spermatids: 76.2;Oligodendrocyte precursor cells: 115.1;Oligodendrocytes: 359.3" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "Hep G2: 17.1;OE19: 13.8;SK-MEL-30: 18.6;U-251 MG: 18.0;WM-115: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 1.7 6.4 15.7 0.8 29.3 1.1 1.5 22.7 18.6 1.0 0.0 4.3 0.5 1.8 3.1 0.7 2.8 2.3 11.4 16.5 17.3 0.8 0.2 3.7 0.3 26.8 24.0 1.3 2.3 0.5 2.2 0.1 28.7 5.3 0.9 3.5 2.9 2.2 8.8 0.3 1.0 1.7 20.2 0.5 1.9 3.5 25.8 0.3 3.3 6.3 0.5 1.8 1.5 50.6 0.1 0.0 5.7 0.4 3.0 4.4 0.1 1.8 0.7 0.8 1.0 2.8 0.2 0.0 0.5 4.4 1.1 0.0 5.6 0.0 1.4 6.6 3.3 0.4 0.0 17.1 0.1 6.0 0.1 2.6 0.0 0.8 0.1 8.4 0.0 0.2 5.7 7.2 6.1 0.2 0.3 0.3 3.9 13.8 0.0 0.5 0.0 0.0 0.0 1.2 2.2 3.5 0.3 0.0 18.6 3.7 0.0 0.3 0.1 0.7 0.7 0.1 18.0 10.8 0.1 0.1 0.5 2.8 22.5 11.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 15.7 29.3 22.7 18.6 16.5 17.3 26.8 24.0 28.7 20.2 25.8 50.6 0.1 0.0 0.0 53.5 0.0 0.4 0.5 0.0 0.0 4.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.6 40.3 0.2 0.5 0.9 0.0 1.3 79.9 0.0 0.0 9.9 1.5 0.5 0.0 0.2 0.0 0.1 0.3 0.0 71.5 0.1 0.0 0.3 9.5 76.2 2.1 0.9 1.8 4.7 0.0 5.7 8.2 115.1 359.3 1.2 0.0 4.1 1.9 0.2 0.0 0.3 0.0 0.4 13.1 2.3 3.1 0.3 1.3 0.0 0.4 0.0 4.5 0.4 0.0 0.4 COPG1 COPG ENSG00000181789 "COPI coat complex subunit gamma 1" Q9Y678 3 129249606-129277773 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037866, HPA037867, HPA045712" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 57000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA037866: AB_2675710, HPA037867: AB_10697085, HPA045712: AB_2679428" "unprognostic (8.86e-2)" "unprognostic (2.22e-2)" "unprognostic (4.22e-3)" "unprognostic (1.15e-1)" "unprognostic (1.81e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (1.22e-6)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (5.64e-2)" "unprognostic (8.90e-3)" "unprognostic (3.29e-1)" "unprognostic (1.23e-3)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (2.99e-1)" "unprognostic (1.60e-1)" 84.7 111.0 66.6 59.0 68.2 59.4 79.8 69.5 80.7 100.4 93.0 107.6 86.7 75.5 157.4 86.8 70.0 53.8 95.5 70.3 73.7 82.7 149.5 84.4 54.8 74.3 71.5 77.9 162.4 96.3 139.0 81.9 77.4 107.7 109.8 33.4 130.7 72.7 75.7 74.4 86.7 72.2 66.4 81.9 114.0 46.5 73.2 53.5 83.3 43.2 67.1 67.2 72.2 73.2 167.8 83.2 119.1 104.0 272.8 219.0 126.9 266.3 251.8 179.5 225.2 153.9 101.2 91.1 150.8 380.7 145.6 98.4 99.5 157.2 193.6 112.0 41.4 151.9 103.2 252.6 247.9 116.4 156.4 230.9 135.6 143.8 235.0 196.1 164.3 68.9 54.2 213.6 219.2 253.4 68.7 117.7 71.3 243.6 100.9 73.3 111.8 178.3 227.3 136.7 74.1 86.1 204.2 150.3 255.9 129.8 167.1 167.6 223.9 96.9 91.7 207.2 104.2 165.7 86.1 158.9 236.4 86.9 190.0 79.1 49.9 37.2 44.1 59.2 53.6 24.9 39.8 43.9 57.0 26.9 30.0 36.2 37.2 57.0 57.3 52.2 43.8 56.2 66.6 68.2 69.5 80.7 70.3 73.7 74.3 71.5 77.4 66.4 73.2 73.2 16.6 16.0 31.5 7.8 19.2 8.8 16.9 35.4 12.0 9.2 18.9 8.6 23.3 17.2 34.6 27.6 4.2 55.6 19.7 77.0 43.0 44.5 10.4 26.2 27.7 22.8 38.6 22.9 14.1 46.5 63.1 32.5 53.0 36.9 15.2 28.6 28.9 56.5 39.0 5.0 14.8 75.1 22.4 31.2 14.8 4.7 41.0 21.6 23.2 7.5 36.5 12.7 18.6 4.5 11.8 40.8 44.6 31.2 68.4 24.4 64.5 39.5 32.6 7.1 19.7 20.2 33.3 24.3 17.0 16.4 10.2 72.2 19.4 27.7 44.6 20.6 COPZ1 "CGI-120, COPZ" ENSG00000111481 "COPI coat complex subunit zeta 1" P61923 12 54301202-54351846 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 70000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic unfavorable (7.84e-4)" "unprognostic (2.79e-1)" "unprognostic (4.51e-1)" "unprognostic (7.54e-3)" "unprognostic (1.46e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (6.40e-5)" "unprognostic (1.02e-2)" "unprognostic (3.56e-2)" "unprognostic (7.44e-3)" "unprognostic (1.18e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (2.16e-1)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (3.41e-2)" 75.1 101.1 70.7 51.0 71.9 58.2 95.3 70.8 86.4 85.8 84.6 83.7 74.1 73.1 125.3 107.0 90.2 55.8 104.0 70.8 71.9 105.1 115.4 74.0 68.4 69.6 70.8 73.0 151.3 106.5 105.7 83.5 69.9 76.1 102.6 104.2 104.9 68.7 104.4 76.0 68.5 79.2 70.9 74.9 89.4 35.9 72.0 96.2 115.3 90.3 93.8 73.2 68.7 73.8 135.4 212.1 149.8 133.2 179.8 234.7 96.5 109.3 166.9 149.9 110.6 122.9 185.5 103.1 180.6 165.9 96.3 102.0 265.0 183.7 181.1 137.0 153.5 99.8 181.8 190.6 183.9 133.3 89.9 172.8 250.0 183.2 294.8 257.5 206.8 103.2 221.7 202.1 199.7 177.3 158.7 141.5 109.2 204.2 160.0 121.8 96.4 145.8 225.7 123.5 140.3 112.5 113.2 197.7 147.2 139.6 274.7 210.0 131.7 92.0 96.8 90.7 108.0 82.6 112.1 100.7 172.5 110.4 164.9 97.5 127.3 95.0 93.6 117.7 100.3 86.4 86.2 84.8 128.0 86.2 69.9 75.2 42.9 114.7 134.6 151.6 116.7 134.7 70.7 71.9 70.8 86.4 70.8 71.9 69.6 70.8 69.9 70.9 72.0 73.8 54.3 57.7 73.3 15.3 64.4 28.7 71.9 137.9 47.8 51.0 91.6 72.0 77.2 68.6 105.7 68.0 22.9 175.3 73.3 62.5 273.9 152.2 19.8 66.8 73.6 58.1 66.9 58.5 13.5 115.6 273.9 73.8 63.7 74.5 87.5 100.9 50.7 95.1 173.1 48.8 15.4 141.4 85.5 64.3 42.6 25.4 62.7 78.8 53.4 7.5 150.5 86.3 76.2 14.6 13.7 113.9 74.0 57.2 132.5 100.9 118.0 208.0 92.8 75.4 19.7 35.8 57.1 64.2 60.2 66.6 35.9 202.2 62.0 99.8 87.5 95.3 CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 301.4;Paneth cells: 324.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 221.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 51: Monocytes - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" 54.4 56.4 20.2 29.7 23.8 20.3 53.4 23.4 27.0 55.7 21.1 70.2 62.9 72.8 14.6 80.2 54.2 44.1 26.1 19.4 22.7 48.2 47.2 53.7 41.9 28.0 23.6 42.7 52.5 24.6 35.1 31.2 25.1 71.0 34.5 6.6 73.2 39.6 13.0 42.4 62.3 36.7 24.2 66.0 77.1 13.9 25.1 21.1 55.8 9.9 18.4 58.3 53.5 26.3 80.9 81.4 37.5 76.0 94.1 81.3 56.6 58.5 118.0 94.2 70.8 134.1 116.0 6.4 111.3 80.8 95.8 67.9 41.9 74.9 16.8 19.4 40.7 54.9 47.3 57.9 148.1 2.3 120.8 110.6 66.3 80.1 37.2 59.7 120.7 49.4 42.7 9.2 54.2 238.4 14.4 11.2 47.7 198.2 73.4 11.2 41.0 14.9 62.6 104.3 40.7 50.8 52.4 139.6 181.6 26.0 178.5 63.0 92.2 63.4 47.4 87.4 35.2 1.6 3.3 14.6 103.4 8.2 66.4 57.3 102.8 8.0 10.9 212.9 8.3 20.0 37.6 14.6 79.0 11.0 21.2 11.4 47.8 11.9 221.8 60.8 55.2 57.8 20.2 23.8 23.4 27.0 19.4 22.7 28.0 23.6 25.1 24.2 25.1 26.3 58.7 3.2 2.2 4.6 53.4 27.9 60.1 90.8 40.9 13.0 53.8 39.0 1.6 50.1 66.4 47.8 8.4 87.8 39.2 301.4 60.7 111.4 8.9 43.6 32.9 52.0 99.0 19.8 1.8 105.0 229.8 35.8 111.1 64.8 28.0 46.7 47.8 22.4 251.8 15.2 2.4 188.6 81.4 138.6 66.4 5.0 39.4 96.3 71.2 10.3 195.3 30.0 41.2 4.5 6.8 136.9 324.9 34.6 64.3 55.6 263.5 84.0 41.2 14.6 52.6 22.1 55.1 8.1 6.6 47.6 31.0 150.5 100.3 54.8 128.0 74.5 CORO1C "coronin-3, HCRNN4" ENSG00000110880 "Coronin 1C" Q9ULV4 12 108645109-108731526 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041737 Approved NA NA 13000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA041737: AB_10804115" "unprognostic (2.86e-1)" "unprognostic (2.82e-2)" "unprognostic (2.83e-1)" "unprognostic (3.96e-1)" "unprognostic (6.50e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.59e-5)" "unprognostic (2.49e-2)" "unprognostic (9.84e-2)" "unprognostic (2.41e-1)" "unprognostic (1.07e-2)" "unprognostic (3.96e-1)" "unprognostic (1.67e-3)" "unprognostic (2.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.39e-3)" "unprognostic (4.90e-3)" 68.5 30.6 36.1 49.7 36.1 52.5 36.6 28.1 36.8 49.9 22.1 116.6 28.9 96.1 24.1 67.7 55.9 54.4 33.7 41.3 39.1 25.8 49.1 76.4 31.6 43.9 37.1 30.4 13.0 36.4 22.0 48.2 39.0 35.8 53.3 10.5 24.6 67.3 30.0 52.1 42.9 142.9 38.3 26.1 45.0 22.5 40.8 47.4 14.2 23.6 33.6 71.5 44.7 53.4 188.2 207.2 274.3 140.8 137.3 186.5 117.3 347.8 372.0 443.2 353.6 245.8 81.5 10.6 88.8 547.9 173.2 85.4 153.3 255.1 558.1 82.8 71.4 313.8 95.3 192.7 123.8 76.6 154.1 173.7 120.3 501.0 376.9 262.3 234.1 51.8 157.0 101.0 473.6 68.4 34.7 90.5 70.5 68.7 197.9 53.3 158.6 121.9 176.0 122.5 75.0 66.3 115.6 16.0 156.6 173.0 83.0 58.0 263.7 316.1 165.1 297.7 296.8 99.4 245.7 232.8 246.3 64.0 215.5 42.3 70.7 32.0 7.4 78.1 3.5 24.6 2.9 4.5 75.7 19.1 1.0 3.3 81.9 12.6 75.2 75.9 7.5 44.7 36.1 36.1 28.1 36.8 41.3 39.1 43.9 37.1 39.0 38.3 40.8 53.4 24.5 54.5 20.7 18.3 27.8 138.0 168.2 47.7 66.0 7.1 18.2 14.1 19.0 18.6 34.6 12.9 2.1 28.4 39.1 41.3 3.9 59.7 58.9 33.6 47.2 51.9 30.9 25.5 32.8 22.7 125.3 38.4 20.4 39.1 41.8 43.3 17.2 49.8 122.2 15.2 39.7 23.4 16.2 71.0 181.4 56.4 22.4 108.8 90.7 37.5 81.7 6.7 8.2 46.3 42.6 76.9 29.8 58.6 31.6 92.8 19.0 30.1 10.5 5.3 13.1 42.8 53.2 26.8 22.9 60.6 167.8 46.8 12.0 9.9 30.7 93.2 COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 90.5" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Late spermatids: 27.4;Respiratory ciliated cells: 12.6;Spermatocytes: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "CAPAN-2: 24.9;SCLC-21H: 10.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: AB_10601261" "unprognostic (7.43e-3)" "unprognostic (8.72e-2)" "unprognostic (1.42e-1)" "unprognostic (5.75e-2)" "unprognostic (2.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (6.45e-3)" "unprognostic (1.02e-1)" "unprognostic (6.82e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (8.11e-2)" "unprognostic (1.81e-6)" "unprognostic (9.91e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (2.02e-1)" 0.7 0.1 0.3 1.0 0.2 1.1 0.9 1.0 0.5 0.4 0.4 6.7 0.2 0.2 1.2 1.2 0.7 0.2 0.1 0.3 0.3 0.8 0.1 0.3 0.2 0.3 0.5 0.5 0.2 0.0 0.9 0.2 0.4 0.7 4.8 0.4 1.4 0.2 0.3 2.5 0.3 0.2 0.1 0.3 0.2 90.5 0.3 3.3 0.1 0.0 1.9 0.5 0.9 0.6 3.1 0.4 0.1 0.1 0.0 0.0 0.2 0.4 0.1 0.3 0.5 0.2 24.9 0.1 0.2 0.3 0.3 1.8 0.7 0.2 0.2 0.9 0.7 0.0 2.0 0.1 0.3 0.2 1.8 0.2 2.7 0.5 0.6 1.7 0.0 0.1 0.4 0.2 0.0 0.6 0.1 0.2 0.6 2.6 0.5 0.1 0.0 0.2 0.1 0.4 10.1 0.3 0.4 0.1 0.0 0.6 0.4 0.0 0.5 0.2 0.5 0.1 0.3 1.6 1.4 0.1 0.1 0.3 0.1 0.8 0.2 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.2 0.2 1.5 0.5 0.2 0.4 0.2 0.3 0.3 0.2 1.0 0.5 0.3 0.3 0.3 0.5 0.4 0.1 0.3 0.6 0.2 0.0 0.5 0.0 0.0 0.5 0.7 3.5 1.2 2.4 0.9 1.3 0.6 0.0 2.1 0.0 4.2 0.5 1.8 8.0 0.0 0.5 36.0 1.3 0.5 0.2 1.2 0.0 0.0 0.6 0.3 0.6 0.0 0.8 0.0 0.2 0.0 0.0 0.1 3.3 0.1 1.3 4.1 0.0 0.0 27.4 0.6 0.3 0.0 0.0 0.0 1.4 2.1 0.0 0.1 9.6 4.1 0.0 0.3 0.7 3.4 0.1 12.6 5.4 0.0 0.4 0.5 61.1 1.7 0.3 0.4 0.4 0.6 0.1 6.5 2.3 COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Supported Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" 134.0 147.5 180.8 52.9 183.9 152.6 125.7 186.1 291.0 166.4 190.2 268.1 334.8 194.0 175.6 197.3 189.5 20.4 781.6 191.8 195.6 254.9 328.5 108.4 71.1 186.0 188.4 161.9 107.3 101.7 159.5 89.9 189.2 162.6 110.4 147.0 108.1 58.1 666.1 121.4 172.3 42.7 182.4 122.9 180.0 170.8 192.7 44.8 129.1 554.1 51.5 188.7 148.6 188.9 137.6 57.8 63.8 251.3 140.0 100.5 103.1 44.5 42.7 30.1 34.3 54.7 284.5 326.8 320.1 70.1 47.7 176.4 36.4 363.3 51.0 60.5 89.1 684.6 66.9 160.4 88.9 319.3 201.9 95.1 475.3 26.0 56.4 129.2 45.1 103.8 49.8 571.1 51.6 134.2 337.9 289.6 117.9 205.5 127.7 381.0 21.2 320.6 453.4 713.3 191.8 115.2 30.9 654.2 351.5 65.0 461.7 201.1 40.1 220.4 286.0 235.8 63.8 140.7 126.3 209.6 310.2 128.2 200.8 345.8 134.7 114.1 177.8 210.5 189.0 209.7 270.6 193.5 212.9 189.8 319.7 294.9 16.6 187.7 266.5 301.9 272.7 252.9 180.8 183.9 186.1 291.0 191.8 195.6 186.0 188.4 189.2 182.4 192.7 188.9 527.8 403.8 485.1 29.7 382.1 490.8 493.5 1431.9 279.4 217.6 561.3 642.7 2146.4 491.8 731.2 605.1 102.2 978.9 416.1 1263.2 2226.5 673.6 834.3 579.3 778.7 436.9 807.5 400.2 27.6 849.4 853.9 502.0 440.4 551.9 362.5 219.3 384.1 1855.5 1066.5 156.5 33.5 1221.3 1027.4 451.1 539.5 266.5 664.8 440.8 732.8 23.4 778.0 545.0 449.0 22.6 32.1 808.6 1338.7 587.5 412.2 448.4 2173.5 1791.0 702.9 282.0 493.0 367.1 555.9 1180.5 505.2 666.4 640.6 1784.9 452.1 428.0 1246.7 715.5 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPLX3 CPX-III ENSG00000213578 "Complexin 3" Q8WVH0 15 74826627-74831802 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 44.2;lymphoid tissue: 110.3;prostate: 122.4;retina: 98.6" "Cell type enriched" "Detected in some" 6 "Bipolar cells: 496.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;Karpas-707: 2.0;SK-BR-3: 1.1;U-266/84: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB079003 Supported NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "CAB079003: " 0.1 7.2 10.6 0.2 9.6 0.1 0.2 18.9 10.2 0.2 4.0 0.4 0.1 0.0 0.1 0.8 0.1 0.0 44.2 18.2 6.7 0.0 0.1 0.1 0.2 8.4 12.7 0.1 0.1 0.1 5.3 0.0 8.3 122.4 0.1 98.6 17.9 0.0 0.0 0.4 0.3 0.0 6.1 110.3 14.9 6.4 21.4 0.1 0.0 0.0 0.2 0.1 0.3 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.1 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.4 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 18.9 10.2 18.2 6.7 8.4 12.7 8.3 6.1 21.4 7.9 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 496.1 0.1 0.0 0.0 0.0 0.0 0.0 77.2 0.0 0.1 0.5 0.0 0.0 3.9 0.1 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 15.2 6.9 0.0 0.0 0.0 0.0 4.9 0.0 0.1 0.0 0.0 0.0 19.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.0 56.0 0.0 0.0 0.0 8.9 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 CPNE2 CPN2 ENSG00000140848 "Copine 2" Q96FN4 16 57092583-57148369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.4" "Cell type enhanced" "Detected in many" "Adipocytes: 84.3;Hepatic stellate cells: 82.8;Oligodendrocytes: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041132 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA041132: AB_2677316" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (4.93e-3)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (2.10e-2)" "unprognostic (9.14e-2)" "unprognostic (2.10e-3)" "unprognostic (8.78e-3)" "unprognostic (2.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" 35.1 7.3 34.5 12.8 50.2 60.6 24.9 41.1 45.3 36.5 36.9 29.2 6.0 20.7 6.6 15.9 28.0 14.3 15.5 36.7 46.6 14.1 9.4 37.2 11.0 52.9 48.1 10.7 7.3 10.9 7.5 27.9 48.6 14.0 28.3 1.7 10.9 17.1 11.7 11.7 21.2 25.1 39.3 18.2 9.2 16.4 61.0 6.3 15.9 13.5 9.2 16.7 18.5 87.4 23.9 45.1 68.0 38.1 12.0 11.6 11.3 25.4 39.8 56.8 39.5 12.7 27.0 14.2 22.7 38.6 31.4 36.7 27.1 15.1 30.6 17.7 15.9 5.9 17.5 10.7 21.6 4.8 0.6 11.1 16.8 22.3 10.8 42.4 84.5 7.6 16.0 0.5 14.5 11.1 7.2 69.9 15.5 11.6 9.5 88.8 21.3 11.9 37.7 9.0 1.4 27.6 32.3 6.9 19.4 30.5 7.5 94.4 60.3 51.6 27.7 13.1 33.5 3.4 3.0 31.8 33.4 20.6 37.0 0.0 1.5 0.8 0.2 0.4 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 1.5 0.1 0.1 0.0 0.2 0.4 34.5 50.2 41.1 45.3 36.7 46.6 52.9 48.1 48.6 39.3 61.0 87.4 84.3 19.2 7.4 8.1 1.5 2.3 17.1 6.0 7.4 0.4 8.2 6.9 2.3 4.3 5.1 5.5 0.0 0.6 1.4 43.4 5.9 4.7 19.9 33.4 13.8 41.0 3.6 0.8 1.0 4.2 2.9 12.3 1.5 39.3 0.0 26.7 82.8 2.0 23.6 0.0 7.4 13.7 4.1 25.3 7.4 5.9 6.8 12.0 7.2 8.4 10.7 3.6 0.0 17.1 86.3 6.2 25.1 7.5 0.8 14.2 35.4 2.6 9.2 0.0 32.9 9.3 21.7 0.6 2.6 6.2 4.3 0.8 8.4 2.1 18.2 16.3 CPNE4 "COPN4, CPN4" ENSG00000196353 "Copine 4" Q96A23 3 131533555-132285410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 34.3;prostate: 25.3" "Cell type enriched" "Detected in some" 10 "Excitatory neurons: 351.2" "Cancer enriched" "Detected in some" 6 "prostate cancer: 22.4" "Group enriched" "Detected in many" 4 "basal ganglia: 34.3;cerebral cortex: 15.2;hippocampal formation: 16.8;thalamus: 12.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.2;AF22: 5.7;Karpas-707: 1.7;RT4: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA032036, HPA078300" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA032036: AB_10600898, HPA078300: AB_2732377" "unprognostic (7.38e-2)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (1.22e-4)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (8.81e-3)" "unprognostic (3.40e-1)" "unprognostic (2.69e-2)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (1.29e-2)" "unprognostic (9.10e-3)" "unprognostic (1.18e-2)" "unprognostic (1.76e-2)" "unprognostic (1.35e-1)" "unprognostic (2.51e-1)" 0.6 0.5 4.8 0.1 34.3 0.0 0.2 0.0 15.2 0.2 0.0 0.3 0.7 0.2 0.6 0.3 0.4 0.0 0.9 16.8 3.7 1.0 0.1 0.4 0.0 0.0 4.2 0.0 0.2 1.9 3.0 0.0 0.1 25.3 0.2 2.0 0.4 3.7 0.0 0.2 0.5 0.3 0.5 0.8 0.5 1.4 12.1 0.0 0.3 0.1 0.0 0.1 0.4 1.2 0.0 6.2 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.8 0.4 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.8 0.4 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.7 1.4 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.8 34.3 0.0 15.2 16.8 3.7 0.0 4.2 0.1 0.5 12.1 1.2 0.9 0.0 0.0 8.8 0.0 0.3 0.4 0.1 0.0 0.8 0.0 0.0 17.5 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.2 0.6 0.1 0.6 4.9 0.0 351.2 0.0 0.0 0.6 3.6 0.6 0.0 0.2 0.0 0.0 0.1 1.7 33.0 0.1 0.0 0.0 0.3 5.6 0.3 1.1 0.0 8.4 0.6 0.3 0.0 8.5 7.1 0.1 0.0 0.0 0.0 17.0 0.0 2.6 0.3 0.6 0.0 0.0 0.4 1.4 1.1 0.3 0.1 0.0 0.0 0.1 0.0 0.9 CPNE5 "COPN5, CPN5, KIAA1599" ENSG00000124772 "Copine 5" Q9HCH3 6 36740775-36839444 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4;heart muscle: 92.7" "Cell type enhanced" "Detected in many" "B-cells: 50.6;Cardiomyocytes: 30.0;Excitatory neurons: 35.1;Oligodendrocyte precursor cells: 36.7;Plasma cells: 89.6" "Cancer enhanced" "Detected in all" "glioma: 11.3" "Region enhanced" "Detected in many" "basal ganglia: 62.4" "Group enriched" "Detected in some" 80 "memory B-cell: 51.6;naive B-cell: 26.8" "Lineage enriched" "Detected in single" 105 "B-cells: 51.6" "Group enriched" "Detected in some" 5 "Daudi: 59.4;HUVEC TERT2: 25.7;U-266/70: 19.7;U-266/84: 17.1;U-698: 28.1" "Region enhanced" "Detected in many" "basal ganglia: 103.3" "Region enhanced" "Detected in many" "basal ganglia: 135.5" HPA031369 Enhanced Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA031369: AB_10601801" "unprognostic (5.71e-3)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.73e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-3)" "unprognostic (2.45e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.00e-5)" "unprognostic (1.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.00e-1)" "unprognostic (3.57e-1)" 6.4 0.9 16.6 10.7 62.4 1.4 2.3 0.0 29.5 3.9 0.0 6.2 5.6 5.8 1.0 2.4 19.9 2.0 92.7 23.0 2.7 4.5 0.8 2.6 23.6 0.0 4.6 6.6 1.0 0.4 11.0 1.4 0.0 5.8 5.0 2.8 3.5 2.5 0.5 1.8 8.6 4.7 1.1 20.0 5.1 25.3 0.8 2.3 3.3 0.2 28.1 4.9 5.7 13.3 0.9 0.0 0.5 0.1 0.1 0.0 0.3 0.2 0.2 0.3 0.5 0.0 0.2 59.4 0.5 0.8 2.7 0.4 0.1 0.4 0.2 0.0 0.0 2.6 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.7 0.0 4.1 25.7 0.2 0.2 1.7 0.5 0.0 0.0 0.4 0.1 0.8 0.0 0.3 0.5 0.0 0.0 0.1 0.5 0.1 0.0 0.0 5.3 0.3 0.0 0.8 5.9 0.4 0.7 0.0 2.1 19.7 17.1 28.1 0.3 6.5 0.1 0.0 0.1 0.0 0.0 0.2 0.2 51.6 0.2 0.0 0.1 26.8 0.0 0.0 0.4 0.0 0.2 0.3 0.0 4.5 16.6 62.4 0.0 29.5 23.0 2.7 0.0 4.6 0.0 1.1 0.8 13.3 2.8 0.0 3.6 1.3 50.6 0.6 0.2 0.2 0.0 13.4 0.3 0.5 30.0 0.0 0.0 0.0 0.0 0.0 1.5 15.1 1.9 0.0 3.3 0.4 0.8 7.4 4.2 0.0 35.1 0.2 0.0 2.8 1.5 1.4 12.6 0.3 5.0 1.0 0.4 0.0 8.6 1.8 0.0 1.9 0.6 4.8 0.0 6.2 3.6 2.8 0.2 1.3 2.1 36.7 0.8 0.5 12.5 0.4 89.6 0.2 2.3 0.1 0.0 1.6 0.0 2.3 1.0 0.8 1.5 1.1 0.1 0.0 2.0 0.2 1.7 0.4 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in some" "B-cells: 32.6;Erythroid cells: 20.4;Kupffer cells: 59.1;Macrophages: 24.9;monocytes: 13.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 9 "HL-60: 9.9;HMC-1: 21.8;NB-4: 9.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" 13.2 0.8 0.1 27.2 0.5 10.5 0.6 0.1 2.9 1.2 1.3 1.5 1.3 0.5 0.2 0.9 1.4 2.1 0.6 0.2 0.2 2.5 2.6 3.2 20.1 0.7 0.5 0.2 0.3 0.1 0.2 9.1 1.6 0.2 1.5 0.0 0.4 0.4 0.2 0.1 4.4 6.3 0.1 24.4 1.7 0.6 2.1 1.6 0.3 1.0 17.9 6.7 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 9.9 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.7 4.2 17.2 0.0 2.4 0.7 4.5 0.9 0.4 0.3 2.2 0.2 0.1 15.6 0.0 2.3 0.0 0.0 1.3 0.1 0.5 0.1 2.9 0.2 0.2 0.7 0.5 1.6 0.1 2.1 1.8 0.3 0.0 4.2 0.3 32.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.0 20.4 0.3 0.0 0.1 0.6 0.0 0.2 1.3 0.3 0.0 0.4 9.7 0.0 0.4 0.0 0.0 59.1 1.4 0.0 0.0 24.9 0.0 1.9 13.3 0.0 0.0 1.5 4.4 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.3 0.5 0.0 0.0 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 49.9;Breast myoepithelial cells: 40.1;Intestinal goblet cells: 56.9;Prostatic glandular cells: 49.3" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 81.8;OE19: 82.7;SK-BR-3: 174.6;T-47d: 139.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" 6.3 8.5 3.5 4.5 3.8 7.6 48.2 4.6 4.7 30.5 4.4 11.5 11.4 12.9 13.0 8.2 19.2 6.7 5.0 3.3 3.5 10.5 14.0 5.8 5.9 3.9 4.1 17.4 13.2 6.7 6.1 6.3 3.7 106.2 15.2 4.9 43.9 7.6 5.6 10.2 9.0 5.7 3.9 7.5 29.3 5.3 3.6 12.0 11.3 5.3 7.4 6.8 6.9 4.7 7.5 10.6 9.8 10.9 6.9 10.0 24.7 6.2 7.2 8.3 7.3 5.1 31.0 13.9 31.7 2.6 6.1 12.0 14.5 9.7 4.5 11.4 5.9 10.3 11.7 8.9 5.6 4.9 8.5 10.9 9.2 7.9 17.9 7.5 7.4 16.5 8.1 16.9 3.8 81.8 9.3 3.8 6.7 82.7 12.7 20.9 10.3 26.1 9.0 5.3 18.5 20.1 6.6 174.6 16.8 12.8 139.9 14.9 4.5 2.5 7.3 5.2 4.9 31.4 17.3 10.6 5.3 8.5 8.2 1.5 2.9 2.2 3.4 1.2 4.5 4.5 1.9 2.4 5.0 4.8 1.8 3.5 0.1 9.4 1.7 5.7 1.8 2.5 3.5 3.8 4.6 4.7 3.3 3.5 3.9 4.1 3.7 3.9 3.6 4.7 7.2 6.4 13.1 3.6 6.2 2.9 13.1 10.1 6.8 5.3 49.9 40.1 2.0 7.2 20.3 1.8 2.1 12.9 5.6 3.6 9.8 14.0 0.4 10.6 5.2 6.9 9.0 8.6 0.4 13.3 17.0 4.8 10.7 13.5 5.7 8.7 4.2 14.2 5.4 0.0 0.4 56.9 6.1 7.5 2.0 0.6 7.2 5.1 5.4 0.0 2.8 6.6 8.2 1.5 2.2 7.9 4.3 2.2 5.3 49.3 4.0 4.1 16.6 8.8 19.7 3.1 5.0 7.4 10.6 6.3 3.0 4.2 4.5 7.6 10.9 7.0 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1113.7" "Cell type enhanced" "Detected in many" "Adipocytes: 459.4;Cardiomyocytes: 863.3;Endothelial cells: 510.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.1;memory CD4 T-cell: 80.4;naive B-cell: 109.9;T-reg: 115.6" "Group enriched" "Detected in all" 30 "B-cells: 109.9;T-cells: 115.6" "Cell line enhanced" "Detected in many" "EFO-21: 321.9;MCF7: 306.5;SK-BR-3: 303.7;T-47d: 266.4;TIME: 259.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 26: Non-specific - Mitochondria" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" 177.6 44.7 160.4 31.3 172.0 1.5 162.5 137.7 259.5 101.6 124.2 101.9 27.0 138.1 36.4 127.3 130.0 47.9 1113.7 172.7 186.4 205.1 52.7 185.7 30.0 157.3 158.7 51.2 46.1 19.2 175.0 49.6 158.6 89.0 8.3 4.1 100.0 72.9 52.5 128.9 82.8 32.0 145.0 104.1 66.1 92.8 191.9 10.4 155.6 42.7 16.5 121.4 100.4 140.8 2.5 201.2 37.9 98.3 4.3 19.9 10.0 17.5 1.9 2.8 1.0 7.1 44.2 0.2 321.9 73.8 4.5 166.8 3.6 50.8 0.1 2.3 1.9 0.2 132.5 73.8 24.3 0.0 25.5 10.5 4.4 5.2 26.2 38.4 192.7 0.2 0.5 1.4 26.8 306.5 0.5 0.6 10.0 45.7 143.4 0.4 7.7 9.9 140.1 0.6 61.6 175.3 30.0 303.7 1.9 4.9 266.4 0.1 259.3 82.7 38.8 2.3 50.5 0.7 0.6 0.9 24.3 0.3 179.3 0.2 1.9 0.0 7.5 0.9 6.8 52.1 80.4 17.2 3.6 109.9 17.8 4.5 1.0 3.7 0.5 0.5 115.6 10.4 160.4 172.0 137.7 259.5 172.7 186.4 157.3 158.7 158.6 145.0 191.9 140.8 459.4 157.0 33.7 17.9 15.0 153.2 96.7 206.4 29.0 2.7 110.0 140.7 863.3 107.2 127.1 189.4 4.2 2.6 8.2 0.9 154.6 106.8 37.9 125.1 28.8 510.4 25.2 9.7 16.4 87.6 30.5 132.9 32.1 126.6 7.6 0.4 346.3 30.4 3.0 94.2 3.0 0.3 81.4 11.8 92.6 84.0 28.0 9.3 156.5 27.2 2.5 57.2 1.0 4.5 3.1 48.9 0.1 14.7 7.0 37.4 0.2 17.0 155.7 4.0 276.1 108.1 339.5 27.8 46.1 20.1 196.8 32.0 32.5 5.9 0.2 103.2 CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Group enriched" "Detected in some" 4 "dendritic cells: 63.8;Plasma cells: 16.0;T-cells: 54.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Cell line enriched" "Detected in single" 34 "SCLC-21H: 12.9" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" 0.3 0.3 0.3 2.3 0.5 1.8 0.5 38.2 1.4 0.3 0.3 0.5 0.6 0.8 0.5 0.3 0.3 1.5 0.2 0.2 0.4 0.1 1.0 1.8 8.8 1.1 1.4 0.3 0.1 0.1 0.1 0.2 4.2 0.3 0.6 0.0 0.7 0.2 0.1 0.3 1.2 0.2 0.5 3.6 0.8 0.2 0.7 4.9 0.2 0.0 3.5 0.8 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 4.6 0.6 13.0 5.6 12.9 0.1 1.5 27.0 3.6 0.2 4.3 33.3 1.2 54.0 10.5 0.2 0.1 6.0 0.3 0.5 38.2 1.4 0.2 0.4 1.1 1.4 4.2 0.5 0.7 1.6 1.1 0.0 1.1 0.3 0.8 1.5 0.4 0.1 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.0 0.1 63.8 0.1 0.0 0.0 1.2 0.4 0.4 0.3 0.0 0.4 0.5 0.0 0.2 1.6 2.0 0.6 1.3 0.0 0.4 0.2 5.9 0.0 0.7 0.0 0.0 8.8 8.1 1.2 0.0 10.3 3.6 0.0 9.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.3 0.5 0.0 0.9 0.1 54.1 0.0 0.0 0.5 CRYBA2 ENSG00000163499 "Crystallin beta A2" P53672 2 218990189-218993422 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.1;pancreas: 16.6;pituitary gland: 13.7" "Cell type enriched" "Detected in some" 34 "Enteroendocrine cells: 860.9" "Cancer enriched" "Detected in some" 15 "pancreatic cancer: 16.0" "Region enhanced" "Detected in many" "midbrain: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 69.6" "Region enhanced" "Detected in some" "pons and medulla: 4.3" "Low region specificity" "Detected in some" HPA062293 Supported NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA062293: AB_2732680" "unprognostic (5.29e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (4.19e-1)" "unprognostic (6.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-1)" "unprognostic (1.66e-2)" "unprognostic (3.75e-1)" "prognostic favorable (7.62e-4)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.19e-1)" 0.3 3.5 0.5 0.0 1.0 0.0 0.0 0.7 0.8 0.0 0.3 2.1 2.8 0.0 0.2 0.2 0.0 0.0 0.1 0.5 0.9 0.2 0.0 0.0 0.0 2.0 11.1 0.0 16.6 1.4 13.7 0.0 5.0 0.8 2.2 0.2 0.1 0.0 0.1 0.2 2.7 0.0 0.4 0.0 4.5 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 69.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 2.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 1.9 0.1 0.2 0.1 0.1 1.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.7 0.8 0.5 0.9 2.0 11.1 5.0 0.4 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 3.8 0.0 0.0 0.1 860.9 0.0 0.1 1.3 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 25.0 0.0 0.0 0.4 10.0 0.0 0.1 1.8 0.0 0.0 0.1 0.0 0.0 0.0 7.5 17.5 0.0 0.0 1.0 3.9 0.0 0.0 0.9 0.0 0.0 0.0 0.6 4.5 0.0 0.3 0.3 0.1 0.0 1.7 0.0 CRYBG1 "AIM1, ST4" ENSG00000112297 "Crystallin beta-gamma domain containing 1" 6 106360717-106572017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 61.9;placenta: 72.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 219.4;dendritic cells: 153.6;Plasma cells: 89.9;Syncytiotrophoblasts: 600.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 93.7;HBEC3-KT: 124.1;hTERT-HME1: 95.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.2" "Low region specificity" "Detected in many" "CAB026378, HPA030948, HPA030949" Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Microtubules, Cytosol" "CAB026378: , HPA030948: AB_2673670, HPA030949: AB_2673671" "unprognostic (1.66e-1)" "unprognostic (3.44e-2)" "unprognostic (9.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (3.69e-3)" "unprognostic (5.61e-2)" "unprognostic (8.97e-2)" "unprognostic (3.53e-2)" "unprognostic (8.89e-2)" "unprognostic (8.60e-2)" "unprognostic (3.25e-2)" 17.0 1.2 0.6 21.9 0.5 24.1 17.3 0.7 0.8 6.8 40.3 25.0 25.4 2.4 6.2 61.9 6.7 8.1 1.0 1.9 0.4 15.3 11.8 9.8 20.4 0.8 0.7 2.3 4.9 5.8 0.4 72.0 0.6 25.2 19.2 0.8 9.3 5.4 1.1 42.1 23.7 4.8 0.5 12.6 10.3 5.1 1.5 9.7 2.6 1.2 33.5 19.0 14.0 0.4 34.7 0.2 0.0 0.1 25.5 93.7 9.9 4.9 33.5 10.8 10.0 2.4 11.5 54.0 2.3 21.7 14.6 54.5 0.2 124.1 5.3 74.0 2.3 0.0 1.5 16.9 12.1 33.4 0.2 44.9 66.7 19.7 95.8 0.1 46.5 41.9 1.7 7.3 28.5 3.5 9.7 10.7 0.4 0.2 21.2 16.4 0.4 0.4 14.9 80.0 2.2 0.2 20.3 31.9 0.3 3.0 16.4 24.3 13.5 11.6 1.5 0.2 34.4 5.7 4.7 57.7 56.0 39.3 26.3 0.3 3.4 0.4 7.4 3.6 10.1 6.6 9.8 8.5 8.6 2.9 5.8 5.7 2.4 4.8 4.1 1.0 9.9 4.0 0.6 0.5 0.7 0.8 1.9 0.4 0.8 0.7 0.6 0.5 1.5 0.4 13.4 12.8 11.9 0.0 24.2 0.0 0.0 0.0 0.0 0.0 31.2 14.1 0.0 0.0 13.0 33.1 0.0 219.4 153.6 0.0 3.9 10.9 0.0 20.2 2.7 4.4 0.0 0.0 0.0 12.5 15.3 2.5 0.0 31.6 1.3 0.1 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.0 5.7 0.0 0.0 0.0 0.0 26.4 0.0 0.0 89.9 0.0 0.0 15.0 8.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 600.1 76.7 0.1 0.0 0.0 CRYBG2 "AIM1L, FLJ38020" ENSG00000176092 "Crystallin beta-gamma domain containing 2" Q8N1P7 1 26321698-26360080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.2;skin 1: 20.3;vagina: 20.6" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 48.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 11.4;BEWO: 23.2;CACO-2: 39.3;CAPAN-2: 25.7;HaCaT: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA029629 Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA029629: AB_10601331" "unprognostic (2.20e-1)" "unprognostic (2.07e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.11e-6)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (6.39e-4)" "unprognostic (1.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.94e-2)" "unprognostic (4.83e-9)" "unprognostic (9.12e-3)" "unprognostic (3.40e-1)" "unprognostic (6.44e-2)" "unprognostic (1.63e-2)" 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 10.2 0.0 2.6 6.5 0.0 0.8 48.2 0.3 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 6.0 0.0 0.4 1.9 0.0 6.1 0.0 0.0 20.3 5.9 0.0 0.0 0.0 1.4 1.5 0.0 0.1 0.0 0.0 4.2 8.4 20.6 0.0 11.4 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.1 0.1 39.3 25.7 0.3 7.7 0.0 0.1 9.7 0.1 6.9 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 0.0 0.0 8.6 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 1.9 6.3 0.0 0.0 0.0 0.2 0.4 2.5 0.4 0.0 0.0 4.5 0.0 1.7 6.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 1.8 0.0 6.7 0.9 0.0 1.9 2.1 0.0 2.4 0.1 0.1 0.0 0.0 0.0 1.4 4.4 0.1 0.0 2.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.6 1.2 0.0 0.0 0.0 CSAG3 CSAG3A ENSG00000268916 "CSAG family member 3" Q9Y5P2 X 152753921-152760222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.3;testis: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 44.2;HMC-1: 25.7;OE19: 65.6;SH-SY5Y: 33.7;SK-BR-3: 31.5;U-266/70: 80.5;U-266/84: 44.0" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "unprognostic (1.56e-1)" "unprognostic (9.48e-2)" "unprognostic (1.41e-1)" "unprognostic (7.12e-3)" "unprognostic (4.99e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-2)" "unprognostic (7.06e-2)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-2)" 0.2 0.0 0.4 0.1 0.5 0.1 0.0 0.2 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.1 1.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.3 2.3 0.0 3.9 0.3 0.1 0.0 0.0 0.2 0.1 0.3 0.4 0.4 0.0 0.0 4.5 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 44.2 0.0 0.0 0.0 0.0 25.5 0.0 0.2 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 21.1 0.0 0.0 0.1 0.0 0.0 65.6 0.3 0.0 0.0 2.9 0.0 0.0 7.0 33.7 0.0 31.5 1.4 0.1 0.0 1.4 0.1 0.1 24.0 0.0 0.0 80.5 44.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.2 1.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 75.0;Distal tubular cells: 19.6;Granulosa cells: 30.7;Muller glia cells: 51.7;Proximal tubular cells: 42.5;Sertoli cells: 72.3;Smooth muscle cells: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 12.4;U-2 OS: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" 6.8 143.8 29.4 1.6 21.8 0.1 3.2 64.5 32.1 69.9 4.1 16.5 0.8 83.5 1.4 3.2 24.1 2.3 288.2 30.5 35.3 40.4 2.6 11.5 0.2 44.4 41.0 133.6 51.1 0.0 20.5 0.4 36.9 26.2 0.5 5.2 1.0 10.4 2.7 2.1 3.2 10.9 26.1 1.1 4.5 31.3 44.9 0.0 2.5 2.7 0.0 27.4 29.0 22.7 0.0 0.2 1.5 0.2 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.9 0.0 0.0 0.5 4.7 0.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 12.4 1.5 3.5 0.0 0.0 1.9 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.1 1.1 0.2 0.0 0.1 0.1 1.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.1 41.8 0.3 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 29.4 21.8 64.5 32.1 30.5 35.3 44.4 41.0 36.9 26.1 44.9 22.7 0.1 0.0 0.0 4.6 0.5 0.3 0.2 0.3 0.6 9.9 0.1 0.6 75.0 0.0 0.0 7.3 2.1 0.1 0.0 0.0 19.6 0.3 1.5 0.2 6.0 0.9 0.0 0.0 6.8 10.4 0.1 5.1 0.0 0.1 0.0 30.7 0.4 0.2 0.2 6.7 11.0 0.0 0.0 0.0 0.0 5.1 5.3 0.3 1.8 0.0 0.0 51.7 0.0 1.0 0.6 2.4 0.0 2.6 0.0 0.2 0.0 42.5 0.7 3.2 72.3 0.4 19.9 2.1 0.3 0.0 0.1 0.3 0.2 0.3 0.0 0.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.2;Breast myoepithelial cells: 737.5;Extravillous trophoblasts: 388.5;Smooth muscle cells: 419.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" 344.5 127.2 713.6 224.5 871.4 41.0 321.8 742.5 717.3 542.4 467.6 2743.3 180.6 1904.4 308.4 884.1 1025.6 152.7 194.2 647.3 735.1 192.5 114.7 386.0 64.9 840.1 837.4 319.0 114.6 188.0 117.0 118.3 719.0 947.2 432.0 24.2 250.1 2571.3 64.0 219.8 503.6 2009.6 713.5 165.6 748.3 44.2 848.5 48.0 186.4 53.8 65.7 1494.5 469.1 766.6 83.0 195.3 52.0 116.4 83.2 107.7 273.6 605.7 514.3 455.3 360.9 211.1 57.7 78.7 36.1 325.0 96.7 144.7 32.7 120.3 321.2 169.5 29.3 90.7 220.1 30.7 387.4 72.1 10.2 99.3 105.3 373.0 163.1 253.1 508.1 34.9 4.5 71.9 302.1 232.9 46.6 11.8 0.8 99.0 73.2 18.3 304.9 266.8 212.6 129.7 27.1 22.5 238.0 503.8 163.9 25.6 87.0 74.3 610.6 303.7 195.7 206.6 250.6 40.5 82.6 30.6 303.5 137.6 202.6 75.5 49.8 65.6 37.4 49.3 36.9 25.0 35.8 34.9 65.0 18.1 20.5 25.2 5.0 34.3 54.2 5.2 54.1 46.5 713.6 871.4 742.5 717.3 647.3 735.1 840.1 837.4 719.0 713.5 848.5 766.6 151.8 38.5 47.8 86.5 21.8 49.2 341.2 24.6 207.7 3.4 123.7 737.5 24.8 21.5 36.9 47.8 0.0 88.8 23.3 96.6 49.0 165.1 21.5 30.1 73.6 86.9 57.9 19.1 2.4 171.7 388.5 86.7 36.7 38.9 27.9 13.9 91.1 28.3 66.0 0.0 2.1 80.0 14.2 29.1 55.8 44.9 41.0 37.0 126.3 10.3 73.5 137.4 15.5 6.6 114.8 140.5 71.4 292.3 61.5 113.8 97.2 28.4 25.2 3.1 144.7 37.7 419.9 2.4 3.2 75.3 34.9 160.9 31.2 30.4 69.7 103.6 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Cell type enriched" "Detected in some" 8 "T-cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SK-MEL-30: 3.0;U-266/70: 4.3;U-266/84: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" 1.1 0.2 0.4 18.5 0.4 6.1 1.0 0.4 0.7 0.6 0.5 1.3 0.3 0.3 0.0 1.6 0.6 5.2 0.5 0.5 0.5 0.6 0.7 2.9 37.4 1.3 0.7 0.1 0.4 0.5 0.3 0.3 1.1 1.5 3.2 0.0 0.5 1.0 0.1 0.7 6.2 0.8 0.6 3.9 2.9 1.1 0.5 10.1 1.1 0.2 17.0 5.8 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 4.3 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 6.2 0.8 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 44.5 0.6 0.4 0.4 0.4 0.7 0.5 0.5 1.3 0.7 1.1 0.6 0.5 0.5 0.4 0.0 3.2 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 4.1 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 3.3 0.0 2.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.0 0.2 0.9 0.1 41.9 0.0 0.0 0.1 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2382.9;Excitatory neurons: 1253.9;Inhibitory neurons: 1124.0;Oligodendrocyte precursor cells: 1418.0;Oligodendrocytes: 433.8" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.1;MCF7: 9.0;SK-BR-3: 5.3;U-266/84: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" 0.2 0.7 79.2 0.2 79.3 0.0 0.9 49.7 75.7 0.1 15.2 1.1 0.1 0.1 0.3 0.1 0.2 2.6 3.8 84.6 56.7 0.0 0.5 0.7 0.1 93.8 72.6 0.5 15.8 0.0 9.0 0.3 71.5 0.9 0.3 7.0 0.8 0.2 0.1 0.7 0.5 0.1 77.7 3.9 0.6 2.6 83.7 0.2 0.2 0.1 0.0 0.1 0.2 76.1 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 9.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.0 17.5 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 79.3 49.7 75.7 84.6 56.7 93.8 72.6 71.5 77.7 83.7 76.1 0.1 0.0 0.0 2382.9 0.1 0.0 0.1 0.0 0.0 24.0 7.9 4.1 12.7 28.6 0.0 1.8 0.0 0.0 0.0 0.1 3.9 6.5 25.6 0.8 0.1 0.8 4.9 0.0 1253.9 6.1 0.2 0.5 0.0 0.9 0.0 0.0 0.0 0.2 0.1 8.4 1124.0 0.1 0.0 0.0 0.7 31.1 1.5 0.2 0.0 69.3 0.0 33.0 0.0 1418.0 433.8 2.2 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.6 0.0 3.3 0.3 4.6 5.9 0.0 0.0 0.0 0.1 0.5 0.3 0.1 CTPS1 "CTPS, GATD5" ENSG00000171793 "CTP synthase 1" P17812 1 40979688-41012565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "Actin filaments" "CAB017111: , HPA051322: AB_2681441" "unprognostic (6.60e-2)" "unprognostic (4.44e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-3)" "unprognostic (2.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.42e-2)" "unprognostic (9.72e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-1)" "unprognostic (8.21e-3)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" "unprognostic (1.89e-2)" 9.1 8.1 4.8 11.1 4.7 6.8 6.7 4.0 5.8 9.3 7.9 8.7 4.4 23.6 5.7 14.9 11.1 10.6 5.3 4.9 5.3 12.4 73.4 7.6 12.4 4.6 4.9 3.4 4.7 47.6 0.0 7.8 5.8 13.5 12.0 2.4 50.6 24.8 7.7 4.6 8.4 51.9 4.7 5.0 4.1 14.7 4.9 17.3 4.8 7.6 17.8 17.7 0.3 5.0 77.8 68.5 95.3 60.5 22.9 30.9 138.5 138.8 57.0 141.2 92.0 131.5 66.6 149.8 55.6 61.7 39.4 38.6 91.5 97.0 139.5 66.5 78.0 87.3 72.3 43.3 87.8 128.0 56.8 34.0 49.2 148.5 103.0 23.0 64.1 102.2 84.7 51.5 99.4 42.9 125.0 38.1 126.8 66.4 81.3 100.9 120.0 93.7 71.4 69.4 118.4 61.7 79.2 77.7 33.9 90.8 30.1 152.9 53.5 78.2 119.6 61.7 167.2 36.8 50.8 134.5 59.8 84.5 97.4 0.0 3.5 0.0 3.6 6.5 5.7 5.2 4.1 4.3 11.0 4.0 3.7 6.1 0.0 6.9 5.9 11.9 6.3 3.4 4.8 4.7 4.0 5.8 4.9 5.3 4.6 4.9 5.8 4.7 4.9 5.0 5.4 6.4 18.4 4.9 10.9 8.0 14.3 9.1 9.6 12.5 4.6 4.7 5.7 21.5 7.0 5.5 6.2 15.4 26.4 2.2 1.9 19.2 32.4 4.7 10.8 8.5 3.0 22.5 14.1 17.2 26.4 8.7 7.1 7.3 1.3 15.8 2.2 29.0 11.0 11.8 18.7 3.4 6.1 2.8 6.2 27.9 10.8 6.8 1.8 7.5 8.7 5.4 7.2 7.1 10.3 19.3 1.1 24.8 15.1 19.3 25.2 12.8 2.8 4.3 39.5 9.3 17.5 11.1 40.6 11.8 7.4 5.6 9.9 20.7 5.8 7.3 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 9 "dendritic cells: 717.8;NK-cells: 867.2;T-cells: 352.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Group enriched" "Detected in some" 22 "HEL: 156.7;NB-4: 363.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" 5.1 2.9 0.8 12.9 0.9 116.3 3.7 1.8 1.6 2.6 0.6 5.6 6.1 6.7 2.8 3.1 4.0 6.2 2.9 0.8 0.9 2.1 6.5 24.0 29.5 1.6 0.7 2.4 1.8 0.5 1.1 3.3 1.2 2.1 6.3 0.0 9.1 3.9 1.3 2.7 6.1 2.7 1.2 42.4 8.3 1.2 1.1 7.8 3.2 0.4 13.9 8.6 2.5 1.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 156.7 0.3 0.0 0.0 11.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 9.1 0.2 0.2 1.9 363.4 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 5.6 0.1 0.0 0.1 0.4 0.1 0.3 0.5 0.0 0.2 9.9 0.3 46.4 3.4 4.8 1376.3 4.0 869.4 5.1 145.3 892.8 37.6 3.7 86.0 636.3 25.7 2276.1 5.4 23.3 23.7 809.3 0.8 0.9 1.8 1.6 0.8 0.9 1.6 0.7 1.2 1.2 1.1 1.1 5.1 0.0 4.2 0.0 9.7 4.6 0.4 0.0 1.8 0.0 2.3 2.2 0.4 2.8 1.4 0.0 0.0 0.4 717.8 0.3 0.0 0.3 2.0 0.9 0.9 1.9 0.0 44.1 0.0 0.0 0.2 4.0 12.8 1.1 71.7 0.1 5.7 1.6 1.9 0.0 0.0 0.2 0.0 5.6 34.1 11.1 0.0 9.9 17.8 0.0 6.1 0.0 867.2 0.0 0.2 0.0 0.0 0.0 57.7 0.3 0.0 1.1 0.8 0.0 0.0 1.6 1.9 0.3 1.2 0.8 6.3 0.3 352.6 0.1 0.3 0.3 CTXN1 FLJ25968 ENSG00000178531 "Cortexin 1" P60606 19 7924491-7926135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 275.1;endometrium 1: 85.7" "Cell type enriched" "Detected in many" 4 "Endometrial ciliated cells: 127.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 69.5;glioma: 56.3;ovarian cancer: 138.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 96.4;HEK 293: 67.5;NTERA-2: 72.4;REH: 57.3;SCLC-21H: 56.2;SH-SY5Y: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016669 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA016669: AB_1847330" "unprognostic (1.49e-2)" "unprognostic (3.52e-2)" "unprognostic (1.79e-2)" "unprognostic (2.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (5.42e-2)" "unprognostic (2.17e-1)" "unprognostic (2.58e-1)" "unprognostic (2.28e-2)" "unprognostic (1.69e-3)" "unprognostic (3.31e-2)" "unprognostic (1.56e-3)" "unprognostic (4.84e-2)" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "unprognostic (9.41e-2)" 6.5 12.5 176.3 0.9 275.1 0.1 3.2 0.0 173.0 36.9 0.0 61.3 0.9 85.7 2.9 2.6 43.0 0.2 1.0 199.1 58.0 11.7 0.4 7.0 0.0 0.0 21.3 6.2 2.2 1.1 57.0 0.3 1.0 16.3 0.4 0.2 6.4 12.4 0.5 4.1 4.7 4.9 0.0 1.4 8.8 27.8 85.5 0.3 2.8 0.1 0.0 21.2 13.2 40.7 33.5 8.1 20.5 96.4 0.0 0.3 4.8 8.5 2.3 4.1 2.4 2.4 5.0 0.2 16.2 2.0 2.2 35.9 4.7 0.9 0.2 3.0 67.5 0.7 5.3 1.5 0.9 1.8 1.9 0.0 2.7 1.4 0.9 9.8 5.4 9.1 21.3 0.3 0.5 40.5 18.5 13.6 72.4 2.4 34.1 57.3 0.0 6.4 15.0 1.4 56.2 94.5 5.2 2.8 9.9 1.7 21.2 0.6 8.3 2.1 33.1 3.9 4.8 0.7 1.0 4.8 8.0 3.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.3 275.1 0.0 173.0 199.1 58.0 0.0 21.3 1.0 0.0 85.5 40.7 0.6 0.0 0.0 3.3 0.7 1.1 4.1 1.5 2.2 0.3 15.3 6.7 0.4 1.5 1.0 9.2 4.2 0.2 0.2 0.5 3.9 7.8 9.5 127.7 22.4 1.6 9.1 0.0 20.6 0.4 0.4 3.0 0.0 7.9 0.0 13.3 0.7 0.1 0.3 0.0 3.5 0.5 2.0 0.3 0.5 27.1 1.2 0.5 1.8 4.7 0.0 0.6 0.0 1.5 2.9 1.7 1.2 1.9 0.0 19.9 0.0 11.9 21.0 0.4 0.0 0.2 17.7 6.0 16.0 0.3 2.0 0.3 0.6 3.2 0.2 6.4 CUX2 "CDP2, CUTL2, KIAA0293" ENSG00000111249 "Cut like homeobox 2" O14529 12 111034165-111350554 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 20.6;choroid plexus: 25.7;liver: 20.4;prostate: 11.4" "Cell type enhanced" "Detected in some" "dendritic cells: 28.1;Excitatory neurons: 175.4;Hepatocytes: 50.9;Horizontal cells: 26.9;Inhibitory neurons: 72.5" "Group enriched" "Detected in some" 4 "liver cancer: 5.2;prostate cancer: 11.2" "Region enhanced" "Detected in many" "cerebral cortex: 20.6" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 6.6;HDLM-2: 2.9;hTERT-HME1: 3.5;SCLC-21H: 6.5;SH-SY5Y: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.87e-2)" "unprognostic (6.98e-3)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.78e-2)" "unprognostic (1.22e-2)" "unprognostic (9.44e-2)" "unprognostic (2.33e-1)" "unprognostic (3.30e-2)" "unprognostic (7.83e-5)" "unprognostic (2.67e-1)" "unprognostic (3.54e-3)" "unprognostic (4.31e-2)" "unprognostic (9.03e-2)" "unprognostic (4.64e-2)" "unprognostic (1.90e-2)" 0.0 0.0 2.3 0.2 1.4 0.2 1.8 0.0 20.6 0.8 25.7 0.3 0.1 0.1 0.3 0.1 0.0 0.0 0.0 3.5 0.0 0.2 20.4 0.0 0.5 0.0 1.5 0.0 0.1 0.0 2.1 0.0 0.0 11.4 0.0 2.3 0.0 2.9 0.1 0.2 0.2 0.0 0.0 0.2 1.5 0.5 5.2 0.2 4.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 6.6 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.5 14.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 2.3 1.4 0.0 20.6 3.5 0.0 0.0 1.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 7.2 0.5 0.0 3.5 0.7 0.0 6.4 2.6 3.0 1.0 2.8 0.1 0.0 0.0 0.0 28.1 0.1 0.0 0.0 1.2 3.7 0.1 0.1 0.0 2.7 175.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 50.9 0.7 26.9 72.5 0.0 0.0 0.6 0.0 0.6 0.0 0.5 0.0 1.9 0.0 0.1 0.0 20.1 1.8 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 10.4;Endometrial ciliated cells: 41.3;Gastric mucus-secreting cells: 10.7;Glandular and luminal cells: 21.1;Paneth cells: 15.4;Respiratory ciliated cells: 29.5;Undifferentiated cells: 15.0" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 6.0 0.0 16.9 0.4 0.6 0.4 21.0 14.5 0.0 0.0 0.0 0.0 9.0 0.7 0.7 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 42.8 15.6 0.0 3.0 7.7 0.0 25.5 0.0 0.8 0.1 0.0 9.6 0.0 0.1 0.1 10.2 0.0 1.5 2.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 1.9 0.1 0.8 0.0 0.0 0.6 0.1 0.6 0.0 2.3 7.3 0.0 0.0 0.0 10.4 1.9 0.0 0.2 41.3 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 10.7 21.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 15.4 0.0 0.0 7.6 0.0 2.9 29.5 0.0 0.0 0.0 0.5 0.0 0.5 3.2 9.1 0.0 0.2 0.0 15.0 0.3 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CXCL17 "Dcip1, DMC, UNQ473, VCC1" ENSG00000189377 "C-X-C motif chemokine ligand 17" Q6UXB2 19 42428278-42442946 "Predicted secreted proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 120.5;lung: 149.0;salivary gland: 145.6;stomach 1: 358.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 513.8;Basal respiratory cells: 988.1;Club cells: 1743.3;Respiratory ciliated cells: 383.0;Urothelial cells: 1584.1" "Cancer enhanced" "Detected in many" "cervical cancer: 170.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 8.7;RT4: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.74e-1)" "unprognostic (3.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.03e-2)" "unprognostic (4.46e-3)" "unprognostic (3.77e-1)" "prognostic favorable (4.92e-5)" "unprognostic (6.68e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.13e-3)" "unprognostic (2.29e-1)" 0.2 0.1 0.1 0.1 0.0 0.0 2.3 0.2 0.1 19.2 0.0 0.8 0.7 0.9 22.3 120.5 27.1 6.5 0.1 0.1 0.0 0.2 0.1 149.0 0.0 0.0 0.0 0.3 42.9 0.0 0.6 0.0 0.0 8.2 0.0 0.0 145.6 0.4 0.0 0.3 0.0 0.1 0.0 0.2 358.6 0.1 0.0 1.1 0.5 0.0 24.2 47.6 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 35.3 513.8 0.3 0.1 0.0 225.5 988.1 1.2 0.4 21.5 10.3 0.0 4.3 1743.3 5.5 0.0 0.0 0.2 0.2 0.0 8.7 0.4 3.0 0.6 3.5 0.0 0.0 1.5 187.4 0.0 4.3 302.2 8.4 16.4 0.1 0.0 0.0 0.0 0.0 1.2 0.0 227.9 0.0 0.0 1.5 0.0 3.9 0.0 0.0 2.6 0.2 0.0 0.5 0.5 339.6 0.0 0.0 0.5 221.2 0.0 0.2 383.0 0.6 0.0 0.0 67.6 0.1 0.6 91.6 0.0 0.0 2.4 0.0 0.2 1584.1 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;intestine: 6.4;lymphoid tissue: 16.3" "Cell type enhanced" "Detected in some" "dendritic cells: 87.6;NK-cells: 15.5;Plasma cells: 36.5;Proximal enterocytes: 17.6;T-cells: 48.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 306.7" "Group enriched" "Detected in many" 5 "dendritic cells: 306.7;NK-cells: 198.9;T-cells: 124.7" "Cell line enriched" "Detected in some" 15 "RPMI-8226: 47.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" 0.6 0.8 0.1 5.9 0.1 7.2 0.5 0.2 0.3 0.5 0.0 1.6 5.4 0.4 0.0 0.6 0.5 1.4 0.4 0.2 0.0 0.5 0.5 3.3 16.3 0.2 0.0 0.4 0.5 0.0 0.1 0.1 0.0 0.4 1.0 0.0 1.8 0.3 0.1 0.6 6.4 0.4 0.0 7.5 2.9 0.3 0.1 3.0 0.9 0.1 5.3 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.1 0.0 0.4 0.3 0.2 80.4 0.2 40.9 45.3 90.3 124.7 8.4 9.9 5.5 51.6 1.9 198.9 0.2 306.7 89.4 35.3 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 13.9 0.3 0.0 0.0 0.0 0.0 0.6 0.5 0.4 0.0 0.0 0.0 0.0 0.0 87.6 3.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 3.2 0.0 0.2 0.0 0.3 3.1 0.3 1.3 0.0 0.7 0.3 0.3 0.0 0.0 1.8 0.0 0.8 6.1 0.0 0.0 4.0 1.8 0.0 2.1 0.0 15.5 0.0 0.0 0.2 5.3 0.0 36.5 0.0 17.6 0.5 0.0 0.0 0.0 0.8 0.6 0.0 0.1 0.0 0.6 0.1 48.3 1.5 3.1 0.1 CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 74.1;T-cells: 58.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 445.8" "Lineage enriched" "Detected in many" 5 "T-cells: 445.8" "Cell line enhanced" "Detected in some" "BEWO: 2.9;CAPAN-2: 11.2;JURKAT: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" 1.7 1.7 0.4 7.1 1.3 1.6 3.3 0.5 0.6 2.8 0.8 4.1 4.4 1.1 1.6 2.7 2.3 5.9 1.0 0.5 1.3 0.9 4.0 4.0 17.0 2.3 0.7 2.1 1.5 0.3 0.4 10.8 2.2 1.5 3.7 2.7 1.9 0.8 10.2 0.7 9.5 1.1 1.6 13.3 8.7 0.5 1.2 4.9 1.4 0.0 10.8 7.2 1.6 2.4 0.2 0.0 0.0 0.2 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.8 11.2 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.2 0.3 0.0 0.2 0.6 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.2 0.7 0.0 1.4 0.2 0.6 0.3 1.0 0.5 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.5 0.2 92.8 0.2 445.8 0.3 26.5 112.1 0.1 0.2 1.3 16.0 0.8 89.8 0.4 0.6 87.0 24.7 0.4 1.3 0.5 0.6 0.5 1.3 2.3 0.7 2.2 1.6 1.2 2.4 0.3 0.0 0.0 0.0 1.1 1.0 0.1 0.0 0.0 1.1 0.2 0.1 0.7 0.0 0.0 0.0 2.1 8.4 4.2 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 5.3 0.0 0.0 74.1 1.2 1.5 0.1 1.3 0.0 1.4 0.8 0.8 0.0 0.0 0.2 0.0 2.8 1.8 0.0 0.0 0.8 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.1 0.0 4.7 0.0 0.2 0.3 0.0 0.0 0.1 1.1 10.3 58.5 0.0 0.1 0.1 CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "pons: 124.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 432.2;SK-BR-3: 209.2;T-47d: 168.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA014753: AB_1847364" "prognostic unfavorable (8.89e-5)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-5)" "unprognostic (1.81e-3)" "unprognostic (3.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.91e-2)" "unprognostic (8.97e-2)" "unprognostic (6.38e-2)" "unprognostic (8.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.89e-1)" 14.8 125.6 22.2 12.3 24.4 4.1 32.8 6.8 23.1 45.0 70.6 26.4 36.6 12.3 57.2 51.9 55.8 17.3 16.2 20.4 33.2 24.5 21.0 30.9 8.3 17.2 23.2 9.4 118.0 76.1 74.1 16.2 124.7 63.3 21.1 9.8 85.0 37.8 6.0 37.3 31.9 9.2 9.8 8.7 48.1 6.0 28.0 3.5 40.8 4.6 12.8 16.4 27.4 17.9 99.3 31.9 2.6 20.5 11.5 52.7 43.3 10.3 12.0 12.3 4.9 29.2 96.9 0.2 23.0 75.5 3.3 83.1 20.3 8.0 4.8 26.1 8.7 12.7 20.4 2.0 21.7 1.3 4.3 8.6 84.1 11.2 1.5 17.9 23.9 0.1 41.2 17.7 4.0 140.3 0.5 4.9 20.9 80.5 49.9 0.3 0.2 31.0 40.0 49.8 73.7 432.2 26.0 209.2 10.4 7.3 168.6 6.2 3.6 25.9 29.4 60.6 3.1 0.4 0.4 0.1 22.6 5.1 14.0 0.3 2.0 0.2 19.2 5.7 24.6 0.6 14.4 13.2 2.1 0.6 1.3 4.2 5.2 20.3 7.7 0.1 0.0 5.8 22.2 24.4 6.8 23.1 20.4 33.2 17.2 23.2 124.7 9.8 28.0 17.9 14.6 28.9 37.8 3.6 3.5 16.4 23.7 16.0 26.2 6.1 37.4 24.6 12.8 20.0 36.7 23.9 0.0 25.1 7.0 22.2 3.9 41.1 6.9 74.5 12.5 18.3 21.6 3.4 14.1 50.5 29.2 15.0 30.1 53.9 15.9 7.3 11.4 11.1 4.7 0.0 10.7 31.7 18.3 7.0 9.8 6.2 3.7 4.1 3.6 9.4 6.0 5.2 2.1 0.5 0.6 30.8 11.4 3.4 15.3 41.6 32.1 11.9 68.5 26.8 6.6 5.1 7.6 6.9 7.2 34.2 27.8 24.8 11.4 0.4 26.2 22.6 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.2;Kupffer cells: 456.0;Macrophages: 469.3;monocytes: 396.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Group enriched" "Detected in some" 5 "Daudi: 52.8;NB-4: 64.2;REH: 54.6;RPMI-8226: 210.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" 40.5 28.4 5.5 158.9 5.3 160.9 15.2 6.5 5.5 12.3 12.4 22.3 19.3 9.3 4.3 8.9 9.9 26.2 8.0 4.7 9.1 8.0 27.5 91.5 97.1 15.1 9.6 6.9 4.0 4.4 2.5 54.6 13.3 6.7 30.6 1.7 7.0 9.7 3.7 2.2 22.3 55.5 12.5 89.0 17.2 4.7 11.1 18.3 5.3 5.5 73.2 46.8 2.3 24.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 52.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.4 3.6 0.6 0.0 0.0 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 64.2 0.2 0.0 0.3 54.6 0.0 210.4 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 20.0 0.0 0.0 0.1 0.1 0.2 0.6 1.6 3.4 0.0 8.9 0.0 2.2 276.3 110.5 0.4 261.6 0.5 39.6 0.3 0.4 62.8 32.8 0.3 0.2 19.2 0.6 237.1 90.9 0.9 162.5 5.5 5.3 6.5 5.5 4.7 9.1 15.1 9.6 13.3 12.5 11.1 24.0 2.4 25.6 25.4 0.7 99.9 1.0 0.1 0.0 0.6 0.1 1.0 3.0 11.0 2.8 13.0 1.8 0.0 0.9 82.7 2.0 0.0 0.0 0.6 0.2 0.1 8.1 0.0 5.2 1.6 0.4 1.1 4.4 4.1 0.1 7.6 0.1 5.0 3.2 157.2 1.7 1.6 0.7 0.0 456.0 25.0 0.7 0.6 469.3 1.8 76.8 396.6 0.1 14.4 0.0 0.1 0.1 0.5 0.0 13.6 0.0 0.6 0.5 7.3 0.7 13.1 1.6 1.2 0.0 0.6 1.9 1.3 1.8 7.5 0.0 1.3 0.1 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "A549: 411.5;Hep G2: 122.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022261, HPA063771" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: AB_2685120" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.0 0.0 0.2 0.4 0.4 0.0 3.7 0.0 0.3 1.7 0.0 0.0 0.1 14.9 0.2 3.8 0.2 0.0 0.0 0.1 1.8 35.3 0.4 0.7 0.2 0.4 2.0 0.0 0.0 0.0 0.2 10.0 0.3 2.9 0.0 0.0 0.3 2.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.2 1.3 0.0 10.5 28.7 1.3 0.2 0.5 411.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.6 0.0 3.2 0.0 0.9 15.8 0.0 0.1 0.1 0.0 0.0 0.0 6.5 122.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 7.0 1.3 0.0 2.6 0.6 0.0 0.1 0.1 0.0 0.0 0.0 16.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.1 1.8 0.4 2.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 1.3 22.8 48.3 142.7 74.0 0.0 11.0 8.6 0.4 0.0 47.0 0.0 0.0 0.1 0.1 0.1 5.9 0.1 0.0 0.7 0.5 0.3 0.0 0.0 0.2 0.0 0.1 2.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 9.8 0.0 61.3 13.1 0.0 0.0 0.0 0.6 0.0 0.0 3.3 19.6 0.1 0.1 0.0 0.2 36.7 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 44.7 0.1 0.1 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.8 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.2 0.0 0.0 3.9 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 6.4 0.1 1.7 1.9 0.0 0.0 0.6 1.9 3.3 0.0 0.2 0.0 1.0 0.0 0.2 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.7 0.1 2.4 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.2 CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" 3.2 1.1 0.6 1.2 0.9 0.9 2.7 0.6 1.5 6.0 0.4 15.1 39.1 1.5 0.5 18.1 3.2 2.4 1.5 0.9 2.4 1.8 40.1 1.2 0.5 0.9 1.1 1.6 0.3 0.0 0.5 0.5 1.1 5.0 7.8 0.1 4.3 1.0 0.6 21.1 41.5 1.9 0.7 1.0 12.0 0.2 0.7 0.8 0.9 0.9 2.6 10.5 11.2 1.9 0.0 4.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.6 0.5 0.0 0.0 0.3 32.0 0.0 0.0 0.0 2.0 0.0 0.0 1.7 9.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.1 0.0 46.3 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.1 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.1 0.0 14.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.6 1.5 0.9 2.4 0.9 1.1 1.1 0.7 0.7 1.9 6.3 0.0 1.8 2.6 0.5 14.0 10.0 8.3 13.1 0.0 0.5 0.3 1.0 5.7 7.1 0.0 0.0 0.1 0.0 58.8 0.0 0.6 1.6 0.2 0.1 3.0 7.8 8.0 0.2 0.0 0.1 3.8 57.6 0.3 0.0 0.0 1.4 30.3 0.4 0.0 0.2 24.8 2.0 0.9 1.6 3.2 4.1 0.3 1.8 0.0 0.0 2.7 0.0 0.0 0.4 1.9 51.9 1.2 0.2 3.5 125.3 2.2 4.9 0.1 0.0 0.3 2.5 0.4 0.1 20.5 21.2 0.3 0.5 0.1 29.6 24.8 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 80.2;liver: 235.8" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 562.4" "Cancer enhanced" "Detected in many" "liver cancer: 30.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 63 "neutrophil: 84.1" "Lineage enriched" "Detected in single" 177 "granulocytes: 84.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 33.0;HaCaT: 14.9;Hep G2: 18.3;OE19: 49.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA058960 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA058960: AB_2683862" "unprognostic (1.73e-2)" "unprognostic (9.70e-3)" "unprognostic (1.21e-1)" "unprognostic (1.16e-3)" "unprognostic (5.40e-1)" "unprognostic (1.57e-1)" "unprognostic (7.15e-3)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-3)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" 1.6 0.1 0.9 1.2 3.3 80.2 0.2 2.3 1.3 6.9 0.3 2.1 9.4 0.1 0.8 26.7 1.1 15.5 0.3 1.8 2.2 27.3 235.8 2.3 0.1 2.8 3.0 0.0 0.6 0.0 0.5 0.4 2.9 0.6 1.8 0.0 3.4 0.6 0.1 3.9 15.0 0.3 1.9 7.8 5.1 0.3 1.9 0.7 0.1 0.6 0.7 2.9 9.0 4.1 0.3 7.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 33.0 0.1 0.2 0.0 0.1 14.9 0.0 0.2 0.0 0.6 0.0 0.1 3.5 18.3 0.0 0.2 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 49.3 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 84.1 0.0 0.1 0.0 0.0 0.1 0.9 3.3 2.3 1.3 1.8 2.2 2.8 3.0 2.9 1.9 1.9 4.1 0.0 9.6 3.7 0.7 2.0 1.0 2.1 2.5 1.2 0.0 0.1 0.1 0.9 62.9 5.0 0.0 0.0 0.0 1.4 10.0 0.0 2.3 0.1 0.9 0.2 0.7 53.1 17.3 0.0 0.2 0.2 0.8 7.7 3.1 1.3 0.0 8.2 562.4 0.0 0.0 0.0 14.4 8.2 11.4 0.3 0.7 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.0 7.4 0.0 0.0 3.2 69.9 32.1 1.9 0.0 0.0 0.7 1.3 0.0 0.3 25.7 6.5 0.0 1.1 0.0 10.9 13.1 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4;placenta: 12.9" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 58.2;Syncytiotrophoblasts: 216.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;CACO-2: 2.7;hTCEpi: 1.8;NTERA-2: 2.2;OE19: 11.2;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 16.9;cerebral cortex: 21.4;hippocampal formation: 16.8" HPA030251 Enhanced Supported NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA030251: AB_10611108" "unprognostic (5.22e-6)" "unprognostic (3.13e-2)" "unprognostic (1.04e-2)" "prognostic favorable (1.07e-5)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-3)" "unprognostic (2.48e-1)" "prognostic favorable (5.76e-5)" "unprognostic (1.51e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-4)" "unprognostic (4.23e-2)" 2.3 3.3 3.7 0.4 19.4 0.0 0.6 2.9 6.2 1.7 1.4 1.0 0.8 2.7 0.1 1.5 1.7 0.4 5.2 2.7 2.7 3.6 5.8 1.6 0.4 4.1 3.5 0.1 2.9 0.0 0.6 12.9 4.6 7.3 0.3 5.8 6.5 0.4 0.2 5.7 0.6 0.2 2.8 0.0 0.7 1.0 4.1 1.9 0.3 0.0 0.6 1.1 1.2 3.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 19.4 2.9 6.2 2.7 2.7 4.1 3.5 4.6 2.8 4.1 3.0 0.0 0.0 2.0 0.0 0.0 3.1 1.9 0.8 0.0 10.7 0.1 3.0 0.6 1.5 1.3 1.8 0.0 58.2 0.0 0.1 0.0 1.3 0.0 11.8 0.5 0.7 5.3 0.0 0.1 0.2 6.1 3.4 0.0 11.0 0.0 3.3 0.0 0.3 5.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 6.5 0.0 26.3 0.0 0.0 0.1 0.3 1.2 0.0 0.0 1.1 0.0 5.7 0.0 0.9 0.0 0.5 0.1 0.0 0.3 0.0 1.4 216.3 0.2 0.0 1.9 0.1 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028569 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" Cytosol Nucleoplasm "HPA028569: AB_10794319" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 49.9 25.4 15.0 29.0 15.2 18.9 47.2 14.3 27.9 58.3 18.9 92.2 30.9 85.0 8.2 37.0 55.4 36.0 106.2 16.8 13.9 27.6 30.4 72.5 21.2 16.2 15.4 48.4 36.4 19.0 38.5 31.9 18.8 53.3 11.0 9.0 41.3 39.3 113.6 51.2 44.4 36.6 11.9 29.6 61.4 42.6 17.4 15.4 31.0 21.1 11.3 59.5 45.3 17.3 79.2 61.1 37.5 47.6 27.5 30.9 57.8 106.0 84.5 84.7 55.5 113.4 23.3 43.4 50.8 93.8 59.6 61.7 36.9 60.3 30.7 64.0 61.2 17.5 76.7 65.9 87.2 42.7 63.1 70.6 73.6 77.0 44.0 50.8 71.2 29.2 56.3 73.2 52.5 51.0 42.4 31.9 58.5 31.8 48.6 52.5 55.3 40.5 51.0 60.9 59.1 41.1 71.4 84.9 61.1 43.8 61.4 33.1 134.8 108.3 49.3 98.1 134.5 81.1 72.4 50.7 86.3 44.0 59.0 32.5 18.0 32.5 23.0 20.3 16.7 15.9 17.8 21.6 16.2 16.6 13.1 12.9 29.8 24.3 14.3 18.6 23.6 14.6 15.0 15.2 14.3 27.9 16.8 13.9 16.2 15.4 18.8 11.9 17.4 17.3 24.1 25.6 10.5 6.5 17.0 100.7 99.7 84.1 27.9 15.2 23.9 15.6 29.2 24.3 35.0 11.0 2.1 50.5 14.5 69.2 17.6 90.3 40.3 27.9 28.2 38.3 27.4 7.0 9.6 88.2 79.1 27.8 40.8 37.5 20.3 24.8 21.4 7.9 22.9 11.8 7.1 48.2 48.8 13.6 22.8 23.6 22.7 16.6 37.4 8.4 25.7 12.8 30.9 6.0 6.7 117.7 49.9 22.6 13.3 46.1 59.6 14.3 18.8 10.7 32.9 19.9 53.0 34.6 15.7 24.4 71.7 93.2 15.1 26.2 29.7 46.3 DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2215.1;Proximal tubular cells: 2834.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 2479.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" 358.3 153.9 486.0 158.7 470.8 121.9 717.3 495.6 726.7 218.6 452.3 322.8 312.8 73.5 653.7 667.7 85.8 129.7 515.4 493.0 498.5 536.2 971.1 236.0 182.9 499.4 495.1 86.0 143.8 866.9 76.9 116.3 510.0 451.5 297.3 116.3 369.9 215.1 273.0 451.0 229.6 97.2 512.7 115.5 185.1 201.3 487.6 173.3 133.7 460.5 324.5 136.5 327.7 516.4 543.0 276.9 557.1 257.2 1339.7 1131.9 350.7 281.3 708.7 387.0 746.1 580.6 427.8 747.3 312.1 440.6 938.5 277.9 397.0 588.3 345.9 498.2 262.1 641.4 279.9 775.8 335.6 206.1 2479.2 648.2 376.5 596.2 222.1 255.4 464.3 358.8 77.0 679.2 558.8 559.1 436.5 585.9 370.2 349.7 429.7 157.4 541.4 658.5 948.1 816.5 263.2 210.1 235.3 548.5 634.9 388.8 338.0 952.8 332.5 259.3 329.8 288.8 346.3 220.9 170.5 610.0 365.7 364.8 315.3 1180.7 439.9 1077.9 472.9 489.1 347.3 461.4 367.8 465.2 748.8 505.3 279.1 419.2 285.8 450.7 402.5 791.0 615.7 792.2 486.0 470.8 495.6 726.7 493.0 498.5 499.4 495.1 510.0 512.7 487.6 516.4 505.2 150.6 613.0 46.0 256.7 289.2 249.4 724.2 190.1 37.9 806.5 1025.9 1079.6 663.4 390.0 310.8 14.6 796.5 395.6 737.5 1197.4 466.9 844.4 154.8 194.7 206.2 371.3 108.8 5.2 670.3 643.2 258.2 243.1 185.6 433.4 219.4 167.8 2215.1 1069.4 30.3 3.9 495.0 524.9 305.0 785.7 325.7 152.2 476.1 1058.3 15.0 871.5 928.6 552.0 33.2 25.0 372.7 612.0 127.5 192.0 355.0 753.6 2834.8 340.5 59.1 151.2 267.2 289.9 462.0 30.1 972.6 684.9 516.3 260.8 456.0 673.2 361.0 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DBNDD2 "C20orf35, HSMNP1" ENSG00000244274 "Dysbindin domain containing 2" Q9BQY9 20 45406057-45410610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1300.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 18.8;Gastric mucus-secreting cells: 20.4;Macrophages: 10.7;Smooth muscle cells: 23.6;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "dendritic cells: 18.7;monocytes: 12.5;T-cells: 9.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043991 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA043991: AB_10966212" "unprognostic (6.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-3)" "unprognostic (2.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-3)" "unprognostic (8.24e-2)" "unprognostic (5.44e-2)" "unprognostic (3.06e-1)" "unprognostic (3.71e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-3)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-2)" "unprognostic (3.48e-1)" 71.5 29.7 627.6 33.6 916.1 7.1 59.4 827.6 1054.5 73.6 462.6 160.9 54.5 106.6 41.7 58.7 102.7 33.1 470.5 645.7 709.8 56.3 10.4 63.1 21.3 871.6 808.2 39.1 39.9 65.3 41.3 42.9 853.0 70.2 91.1 34.9 47.7 89.4 316.2 68.6 78.4 100.9 739.9 30.3 82.2 14.4 822.1 23.2 37.2 248.2 27.3 118.7 69.7 1300.9 78.0 13.6 10.8 76.3 6.8 3.0 15.0 44.7 48.4 36.7 24.8 37.2 103.4 1.1 7.7 44.4 13.9 112.1 74.7 4.0 22.4 0.6 43.9 64.5 57.0 34.3 43.1 3.5 94.0 1.2 12.6 13.9 12.8 63.5 25.3 64.8 4.7 1.5 2.9 99.0 5.6 4.9 14.0 50.8 80.0 0.3 1.0 0.7 105.3 1.4 24.8 12.7 15.6 8.4 99.3 7.6 104.0 19.9 41.1 1.5 72.5 48.8 49.5 1.1 1.6 0.3 5.3 0.6 10.9 0.0 10.4 0.0 9.1 12.5 3.3 0.2 8.0 6.8 7.6 0.3 7.4 6.9 0.5 0.8 7.2 18.7 7.4 4.5 627.6 916.1 827.6 1054.5 645.7 709.8 871.6 808.2 853.0 739.9 822.1 1300.9 0.3 3.2 0.5 0.0 3.3 0.0 0.2 0.1 18.8 0.0 0.6 0.3 1.0 0.0 2.5 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.3 0.4 0.2 2.7 0.0 2.1 0.0 0.0 0.0 7.3 20.4 0.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 10.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.5 0.0 3.9 0.4 0.9 0.0 5.3 0.0 0.0 0.6 23.6 0.1 0.0 32.7 0.6 0.0 5.3 0.1 0.4 0.3 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DCXR "DCR, HCR2, KIDCR, P34H, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 1851.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 812.0;Hepatocytes: 3510.3;Proximal tubular cells: 2919.4" "Group enriched" "Detected in all" 5 "liver cancer: 305.9;prostate cancer: 163.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 365.2;MCF7: 446.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Uncertain Nucleoli,Microtubules NA NA 4000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Microtubules" "HPA023371: AB_1847530, HPA023863: AB_1847531" "unprognostic (3.33e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-1)" "unprognostic (1.16e-2)" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (4.54e-3)" "unprognostic (1.86e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-2)" "prognostic favorable (4.70e-4)" "unprognostic (1.72e-1)" "prognostic favorable (2.13e-4)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.10e-2)" 106.7 43.9 93.1 15.2 95.3 25.3 107.6 102.5 111.1 52.0 84.4 49.6 29.2 39.5 281.3 96.6 59.2 10.8 132.7 87.6 100.7 239.9 1851.6 61.0 16.6 102.4 98.0 70.0 71.6 46.1 63.9 20.2 105.9 138.0 20.9 9.7 103.4 33.6 187.3 87.6 44.4 10.4 91.8 35.8 167.0 44.8 105.9 26.1 60.7 80.6 19.6 48.9 62.1 94.9 50.3 68.2 32.8 56.4 123.2 31.8 80.4 25.0 33.9 68.5 48.4 122.0 21.3 100.3 47.4 35.9 9.4 57.4 59.6 52.6 24.1 21.4 145.9 96.9 48.8 365.2 143.2 75.6 114.5 44.6 62.2 22.7 79.8 16.0 41.1 61.1 112.4 76.3 36.5 446.2 63.7 184.1 35.0 242.9 71.3 57.9 42.0 135.3 53.3 71.9 85.5 51.0 35.5 287.5 46.0 19.7 213.4 74.5 20.5 36.6 45.0 48.9 48.2 73.7 56.2 50.2 31.4 83.0 26.7 49.5 92.6 77.9 66.5 92.0 64.1 86.8 83.0 64.7 151.3 99.2 117.7 85.4 47.2 108.9 88.1 121.6 98.9 110.1 93.1 95.3 102.5 111.1 87.6 100.7 102.4 98.0 105.9 91.8 105.9 94.9 29.0 51.3 198.2 16.6 133.6 58.5 200.3 113.5 109.8 16.0 301.8 269.2 120.7 183.0 123.4 178.4 18.8 372.1 116.6 152.9 812.0 41.4 6.0 67.0 50.9 44.6 54.7 335.7 4.7 42.6 450.6 65.0 151.4 102.3 64.7 62.7 138.5 3510.3 164.7 21.9 9.0 170.4 189.2 165.7 65.6 22.6 70.8 82.3 179.7 1.9 52.8 145.1 78.2 5.5 10.5 30.4 135.7 47.4 98.6 215.2 158.9 2919.4 55.4 26.5 19.7 40.6 79.6 10.3 48.2 219.9 73.2 342.6 135.7 118.6 154.6 178.8 DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 271.2" "Cell type enriched" "Detected in some" 7 "Collecting duct cells: 11.0" "Group enriched" "Detected in some" 4 "liver cancer: 0.8;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046399 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046399: AB_10960992" "unprognostic (9.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.54e-2)" 25.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 271.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 1.5 0.0 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.0;intestine: 34.8;skin 1: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 82.8;Paneth cells: 77.0;Proximal enterocytes: 298.9;Respiratory ciliated cells: 144.8;Squamous epithelial cells: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.6" "Group enriched" "Detected in some" 16 "OE19: 69.3;T-47d: 104.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" 0.4 0.1 6.4 1.0 7.2 0.2 6.1 18.3 7.1 4.8 3.6 8.9 24.7 3.3 0.5 37.0 2.0 6.5 0.2 5.1 4.5 10.8 0.9 1.6 0.6 5.9 5.3 1.0 6.9 0.4 3.3 0.4 6.0 2.3 4.5 0.2 8.6 2.1 0.3 54.2 34.8 0.5 4.8 0.8 20.1 1.1 5.3 0.1 2.4 0.0 1.8 6.5 10.1 4.9 0.0 0.3 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.3 0.0 0.0 0.0 0.0 1.1 1.6 0.0 0.0 4.2 0.4 0.3 0.1 69.3 0.0 0.4 0.0 3.6 0.0 1.6 5.2 0.1 0.0 3.1 0.0 0.1 104.4 1.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.5 0.4 6.6 1.6 0.0 0.0 10.9 0.1 0.7 0.7 6.8 0.0 1.0 0.2 0.2 0.0 0.1 0.0 0.7 6.4 7.2 18.3 7.1 5.1 4.5 5.9 5.3 6.0 4.8 5.3 4.9 0.7 3.2 5.0 5.2 3.7 1.8 3.3 22.9 1.2 4.6 24.2 15.2 0.6 37.1 34.8 82.8 0.0 7.7 3.3 24.2 1.9 19.0 1.2 15.3 4.3 3.8 55.3 1.3 0.5 1.5 4.9 1.3 54.6 28.9 9.5 0.9 0.4 0.3 1.6 0.0 0.4 53.5 34.6 0.9 0.6 1.6 0.3 1.5 0.0 3.7 0.5 1.2 12.3 0.0 1.5 2.4 77.0 0.0 3.7 1.7 298.9 0.4 144.8 22.0 0.0 1.1 3.1 3.2 4.0 86.9 15.3 37.4 2.5 0.2 69.6 21.0 DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.2;intestine: 14.4;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "B-cells: 27.5;dendritic cells: 30.1;granulocytes: 15.9;Hofbauer cells: 14.6;NK-cells: 35.0;T-cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 22.5;HEL: 15.1;HMC-1: 44.7;MOLT-4: 14.7;THP-1: 13.8;U-937: 31.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Centrosome" "HPA042758: AB_10962357, HPA042839: AB_10959898" "unprognostic (5.94e-2)" "unprognostic (1.41e-3)" "unprognostic (4.26e-2)" "unprognostic (1.93e-3)" "unprognostic (1.21e-1)" "unprognostic (1.72e-3)" "unprognostic (3.91e-2)" "prognostic favorable (1.23e-4)" "unprognostic (7.76e-3)" "unprognostic (4.45e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.95e-4)" "prognostic favorable (7.51e-14)" "unprognostic (1.37e-3)" "unprognostic (1.27e-1)" "unprognostic (4.53e-2)" "prognostic favorable (5.62e-4)" 2.2 1.0 1.4 21.4 1.3 21.2 1.0 1.5 1.7 0.9 1.5 3.0 4.9 0.9 0.0 1.9 1.3 2.8 1.1 1.4 1.5 1.6 2.1 5.8 32.1 2.4 1.8 0.3 1.3 0.1 0.8 1.8 2.2 1.6 1.2 0.0 3.0 0.5 0.8 1.4 14.4 1.2 1.8 35.1 5.2 0.4 2.8 20.5 1.7 0.3 14.9 3.0 1.3 2.6 0.2 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.5 0.0 22.5 0.1 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.0 15.1 0.0 1.6 0.0 7.5 44.7 0.0 0.0 0.1 0.0 0.0 0.0 7.4 0.3 9.4 0.1 0.0 14.7 11.5 0.0 0.5 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 13.8 0.1 0.0 0.0 0.0 0.0 0.4 2.0 10.6 0.1 31.3 0.0 18.3 19.9 32.8 40.1 32.4 35.0 23.8 28.6 35.0 19.5 18.7 35.7 32.1 27.8 23.8 35.0 11.2 35.6 37.1 1.4 1.3 1.5 1.7 1.4 1.5 2.4 1.8 2.2 1.8 2.8 2.6 0.3 3.2 3.0 0.0 27.5 0.4 0.1 0.0 1.2 0.0 0.6 0.6 1.3 2.8 0.0 1.8 0.0 0.2 30.1 0.5 1.9 0.4 0.7 1.5 0.2 0.4 0.0 5.7 0.4 0.0 0.2 0.7 1.5 0.3 15.9 0.5 1.1 0.7 14.6 0.0 0.5 0.9 0.0 11.6 9.2 0.6 0.0 13.8 3.6 2.8 10.9 0.0 35.0 0.0 0.5 0.3 0.4 0.0 13.5 0.2 2.9 6.2 1.6 0.0 0.0 0.0 0.3 0.3 1.2 1.6 0.1 0.3 34.5 0.7 1.0 0.1 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DEUP1 "CCDC67, FLJ25393" ENSG00000165325 "Deuterosome assembly protein 1" Q05D60 11 93329971-93438487 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.8;testis: 16.4" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 16.8;Respiratory ciliated cells: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (4.68e-1)" "unprognostic (3.25e-1)" "unprognostic (3.93e-1)" "unprognostic (7.24e-3)" "unprognostic (2.09e-1)" "unprognostic (4.13e-1)" "unprognostic (2.29e-1)" "unprognostic (1.79e-2)" "unprognostic (1.16e-1)" "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-3)" "unprognostic (1.33e-1)" "unprognostic (6.03e-3)" "unprognostic (8.59e-2)" "unprognostic (2.25e-1)" 0.0 0.5 0.4 0.0 0.2 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 1.1 0.0 4.8 0.1 0.0 0.4 2.1 0.3 0.0 0.3 0.0 0.7 1.1 0.3 0.8 0.3 1.5 0.0 0.6 0.9 0.1 0.1 0.2 0.3 0.0 0.2 0.0 0.1 0.5 0.1 0.0 16.4 3.6 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.4 2.1 0.7 1.1 0.6 0.5 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 16.8 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 21.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1129.5;liver: 623.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1031.9" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 58.3 1129.5 35.7 19.8 58.5 1.6 104.8 125.3 73.0 54.9 30.4 55.6 62.2 13.1 1.6 296.1 60.4 42.2 18.0 55.9 63.9 48.6 623.5 215.9 9.4 216.2 91.3 28.5 30.5 157.9 17.0 21.6 158.9 128.6 40.5 15.8 136.2 8.3 197.7 247.6 29.6 12.6 129.3 134.1 98.9 74.2 87.9 10.1 15.4 11.1 33.9 13.5 103.9 280.7 342.1 58.5 210.6 257.1 1031.9 219.0 50.5 94.8 160.3 130.7 268.6 341.6 210.2 55.3 191.5 82.4 427.4 319.2 250.5 501.3 118.3 8.3 159.6 303.3 131.8 421.7 168.9 126.7 68.2 161.0 429.0 397.6 74.7 66.7 67.2 124.5 224.7 0.2 50.2 143.5 25.8 111.4 592.0 90.7 164.2 0.3 54.2 166.3 735.3 257.1 144.5 53.2 185.0 337.5 123.1 221.6 441.5 143.3 62.2 45.3 130.0 66.1 183.9 22.7 55.0 91.2 32.8 215.3 60.4 5.1 1.5 0.7 6.0 1.8 0.3 3.7 2.5 2.6 5.2 1.3 2.2 2.9 0.0 2.7 0.7 3.0 0.4 4.4 35.7 58.5 125.3 73.0 55.9 63.9 216.2 91.3 158.9 129.3 87.9 280.7 6.2 298.1 682.3 12.4 13.3 31.5 17.3 150.6 79.1 9.7 87.9 33.1 15.3 145.8 205.2 68.0 0.0 35.2 6.4 133.3 3.9 55.3 22.9 14.5 5.8 13.5 24.0 71.6 14.5 76.5 34.4 17.5 38.7 44.7 32.2 26.4 111.0 1091.4 28.0 5.0 8.7 39.2 69.2 68.9 8.2 77.2 14.0 9.4 14.2 1.9 6.8 3.6 2.1 5.5 62.6 48.6 27.7 7.9 1.8 52.4 22.6 14.4 136.3 6.4 0.0 1.5 23.2 5.4 14.7 145.4 80.4 30.6 10.6 442.4 35.2 45.2 DHDH HUM2DD ENSG00000104808 "Dihydrodiol dehydrogenase" Q9UQ10 19 48933699-48944969 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 17.3;kidney: 18.0" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 213.7;Proximal tubular cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Group enriched" "Detected in many" 33 "granulocytes: 4.2;T-cells: 2.3" "Cell line enhanced" "Detected in some" "JURKAT: 3.2;U-266/70: 3.2;U-266/84: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044131 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Actin filaments" "HPA044131: AB_10966968" "unprognostic (1.54e-1)" "unprognostic (2.72e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.91e-4)" "unprognostic (3.33e-3)" "unprognostic (1.45e-1)" "unprognostic (5.81e-6)" "unprognostic (1.56e-2)" "unprognostic (5.88e-2)" "unprognostic (4.96e-2)" "unprognostic (3.30e-2)" "unprognostic (5.08e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" 0.2 0.4 1.6 0.0 1.6 0.1 0.2 1.9 3.3 0.3 1.0 0.3 10.5 0.1 0.0 0.8 0.3 0.2 0.1 1.7 1.7 18.0 0.4 1.1 0.2 1.2 1.3 0.6 0.4 0.5 1.8 1.3 1.2 3.2 0.0 1.7 0.4 0.1 0.2 0.2 17.3 0.0 1.3 1.7 0.7 1.9 2.7 0.1 0.1 0.0 0.2 0.3 0.4 1.6 1.4 0.0 0.1 0.7 0.4 0.3 0.5 0.0 0.2 0.2 0.7 1.4 1.1 0.0 0.2 0.0 0.9 0.4 0.5 1.0 0.4 0.5 1.1 2.0 0.5 0.5 0.0 0.0 0.4 0.2 0.1 0.5 0.0 0.3 0.0 3.2 0.7 0.2 0.0 0.3 0.0 0.1 0.3 2.1 0.9 0.7 0.1 1.0 0.1 0.4 2.1 1.1 0.2 0.1 0.5 0.1 1.0 0.0 0.0 0.0 0.8 0.3 0.0 3.2 2.8 0.8 0.7 0.0 0.2 4.2 0.0 0.5 0.7 0.0 0.4 0.0 0.8 0.3 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 0.6 0.2 1.6 1.6 1.9 3.3 1.7 1.7 1.2 1.3 1.2 1.3 2.7 1.6 0.5 3.2 6.4 1.0 1.0 0.8 2.4 3.3 2.2 2.4 1.0 3.4 0.7 1.5 4.6 3.7 0.0 0.2 0.4 1.5 9.8 2.2 0.7 0.3 0.5 0.8 0.0 0.4 1.0 0.4 0.2 0.5 4.1 0.8 1.3 0.1 0.0 0.0 12.9 0.0 1.2 5.0 2.0 0.8 0.0 2.4 0.0 1.7 0.0 0.0 0.0 1.6 0.0 0.0 0.5 1.5 3.6 0.0 0.0 3.5 213.7 77.8 0.5 4.5 0.0 1.2 0.4 0.0 0.8 3.1 0.1 0.1 0.6 0.4 2.7 3.2 DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" 3.1 7.0 9.9 5.7 8.6 41.8 5.4 17.1 9.6 6.4 11.8 4.8 4.4 3.0 6.6 8.8 4.1 2.9 2.8 8.6 15.3 12.2 23.6 4.7 6.6 13.0 14.9 3.5 6.6 7.9 6.3 4.5 14.0 19.4 3.6 8.3 12.7 10.6 1.3 7.4 4.0 2.2 10.1 10.2 5.9 3.0 13.0 4.6 4.7 2.3 6.9 9.5 6.3 9.5 12.1 7.6 17.4 22.2 2.6 3.8 16.8 6.4 8.3 11.6 17.7 23.5 7.1 32.8 10.7 1.4 13.4 10.5 24.8 7.1 4.9 33.5 23.9 18.4 13.9 13.0 6.5 9.5 2.1 2.8 6.3 7.3 7.7 8.1 3.6 22.7 42.3 11.0 2.3 21.7 20.9 15.9 10.7 31.4 1.0 32.8 16.4 25.5 21.8 20.2 24.8 20.8 10.1 69.5 13.9 9.1 46.4 15.2 1.2 3.7 11.1 9.0 8.9 25.5 25.7 20.7 11.0 11.9 9.4 0.9 4.4 3.1 8.5 6.9 10.4 7.1 10.8 10.7 5.9 8.6 10.9 8.1 55.3 9.4 6.8 3.2 11.4 5.8 9.9 8.6 17.1 9.6 8.6 15.3 13.0 14.9 14.0 10.1 13.0 9.5 2.4 3.2 4.2 2.3 6.7 1.5 10.2 12.3 12.0 6.1 7.1 5.7 0.4 8.6 5.4 7.3 2.1 27.7 4.4 4.3 9.8 10.6 11.9 3.4 1.1 4.5 3.0 106.1 0.7 2.7 22.2 2.1 7.7 6.3 1.3 1.2 6.4 5.5 6.2 5.0 4.4 4.2 2.0 0.8 3.0 5.2 1.2 2.1 5.4 1.0 15.5 8.2 10.3 3.0 1.0 2.5 2.4 0.4 12.8 11.5 2.8 3.2 2.2 5.0 6.6 0.9 1.1 6.1 22.5 9.4 1.7 13.5 7.0 0.5 6.4 5.8 DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 840.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" 62.1 103.4 50.8 43.8 53.9 61.0 58.5 59.2 75.4 48.9 50.2 73.0 108.9 49.8 96.5 44.3 45.9 59.1 47.1 49.9 55.1 100.5 146.4 64.2 45.5 62.3 54.9 64.9 76.8 226.8 54.7 29.6 63.3 409.9 69.5 111.1 317.5 134.6 615.8 46.6 181.0 51.0 57.8 45.4 182.3 9.8 52.0 39.2 120.3 136.0 49.4 51.7 41.1 65.6 221.3 52.9 41.8 89.3 219.6 74.4 42.8 74.3 186.4 26.5 59.0 37.3 149.8 21.5 41.7 76.8 78.0 92.7 57.2 108.3 34.5 156.1 36.0 53.7 28.7 60.9 110.1 71.8 1.7 63.3 116.7 47.6 153.0 50.8 52.5 66.2 18.2 52.6 61.4 59.2 40.9 67.2 18.6 151.2 55.4 42.7 50.8 24.4 118.3 70.5 83.4 99.8 72.6 118.0 168.2 52.7 72.7 32.5 35.8 126.6 38.7 36.9 44.2 18.3 7.9 45.0 62.6 64.8 93.5 743.5 213.1 519.6 335.7 159.1 340.6 184.4 238.9 298.5 185.0 167.0 134.6 258.5 835.4 294.7 224.0 388.8 215.5 450.2 50.8 53.9 59.2 75.4 49.9 55.1 62.3 54.9 63.3 57.8 52.0 65.6 109.6 54.5 102.5 16.0 72.2 34.0 70.3 233.2 52.3 25.7 81.2 57.4 27.6 160.2 138.4 86.5 83.4 29.6 210.4 101.3 19.6 222.5 2.1 56.2 55.5 89.7 46.5 20.4 12.2 165.9 88.7 87.9 120.8 120.0 178.5 22.9 48.5 166.4 94.4 42.1 19.0 102.2 386.6 54.5 70.6 3.5 82.3 98.7 108.5 16.9 172.5 94.4 299.7 26.2 20.1 210.6 114.5 84.2 99.0 263.4 840.4 44.1 57.0 70.7 85.5 66.4 73.7 1.6 2.9 47.0 25.4 20.8 152.1 19.7 79.2 47.1 DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 227.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 102.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617" "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" 10.7 8.4 8.1 6.8 10.4 3.8 8.4 12.6 8.5 8.8 11.9 10.1 7.6 6.2 6.8 7.5 6.1 5.3 13.2 7.6 8.5 42.7 129.5 5.4 8.5 9.5 8.6 10.0 18.0 12.7 5.6 7.7 9.5 12.9 10.8 7.5 13.1 5.7 18.7 5.6 6.9 5.7 8.8 7.8 10.9 4.7 9.1 10.5 11.6 23.1 9.7 6.3 6.1 11.4 27.0 20.4 29.8 23.8 18.2 10.8 35.9 13.3 8.6 23.4 20.6 13.1 15.7 19.3 4.3 8.4 10.8 37.4 31.6 10.4 26.6 10.9 14.2 10.6 7.7 10.1 17.8 4.2 3.8 13.3 7.9 13.7 5.5 9.2 13.0 23.1 16.7 15.1 6.3 52.3 14.4 7.7 16.7 24.9 4.7 24.3 9.7 16.5 15.2 6.4 7.7 34.9 26.3 46.3 15.4 31.7 102.2 15.2 5.8 7.5 5.4 15.8 9.9 13.4 10.3 12.6 9.7 7.4 12.8 23.8 6.8 15.4 4.2 9.2 4.5 13.0 3.2 2.7 11.9 9.9 3.1 4.1 19.4 14.3 17.0 17.3 5.7 4.9 8.1 10.4 12.6 8.5 7.6 8.5 9.5 8.6 9.5 8.8 9.1 11.4 6.9 12.8 38.8 21.5 21.3 5.2 6.7 5.3 10.2 13.3 13.7 8.3 31.1 28.6 7.8 16.5 10.4 35.4 23.2 14.6 19.6 10.9 3.5 8.8 17.3 8.1 11.3 21.9 12.8 11.1 25.1 8.1 21.9 20.8 8.8 45.2 11.0 227.4 10.3 26.9 17.3 18.0 4.1 15.3 10.1 4.2 12.5 13.5 5.4 17.8 13.4 10.4 8.2 15.6 20.5 12.4 9.6 12.0 22.6 9.6 9.4 62.5 5.2 19.2 13.1 10.6 7.4 6.7 3.8 16.2 6.0 13.5 8.4 21.8 16.6 7.8 DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.5;Inhibitory neurons: 21.5;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: AB_2682491, HPA062700: AB_2684838" "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" 6.6 4.2 4.2 4.5 4.9 9.8 6.0 4.4 5.2 10.1 3.1 16.7 6.2 11.2 8.0 8.1 8.5 5.6 10.2 4.5 3.9 6.0 4.8 5.3 6.7 4.1 4.3 7.9 3.7 7.0 3.8 5.2 4.1 8.1 8.6 6.0 5.1 7.2 8.2 6.9 7.9 8.1 3.8 4.8 8.0 6.6 4.2 6.4 5.1 6.3 5.4 11.9 7.0 5.1 10.3 8.4 15.9 6.6 6.0 7.8 11.3 6.0 10.3 13.5 9.9 29.1 9.0 11.4 10.4 11.4 10.4 16.0 11.0 17.5 13.2 2.9 5.2 15.4 14.3 16.7 7.2 18.4 7.7 9.0 11.3 11.7 10.9 8.3 6.1 19.4 16.0 6.5 7.2 8.2 30.0 14.0 9.1 18.5 13.5 14.5 23.2 9.5 5.0 11.8 13.9 11.1 16.4 9.6 15.4 9.9 13.3 14.7 6.0 19.1 10.6 7.8 12.6 6.5 9.2 12.3 10.9 8.2 10.4 0.0 3.0 1.2 2.9 2.7 2.9 2.5 2.4 3.1 4.0 2.9 4.5 2.4 0.6 3.9 2.4 1.4 1.7 2.9 4.2 4.9 4.4 5.2 4.5 3.9 4.1 4.3 4.1 3.8 4.2 5.1 5.4 0.0 3.7 16.0 3.8 0.5 1.4 2.2 7.4 5.1 2.3 3.0 6.7 4.3 4.8 1.8 4.2 3.7 4.1 4.2 1.9 2.4 3.7 2.5 6.6 3.8 5.4 5.5 23.5 1.1 2.4 3.8 7.7 3.2 8.2 6.1 5.7 7.0 5.0 5.0 21.5 6.3 4.1 4.7 4.0 0.8 6.2 3.3 3.6 14.0 3.6 3.3 6.2 22.6 24.8 2.0 5.8 6.4 4.9 2.7 4.6 2.2 4.3 4.7 0.0 4.7 3.9 1.9 9.4 4.5 2.0 3.0 4.5 4.9 5.4 1.1 DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101561351-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.0;placenta: 17.8" "Cell type enhanced" "Detected in some" "Endothelial cells: 7.8;Fibroblasts: 27.9;Leydig cells: 10.8;Muller glia cells: 8.1;Peritubular cells: 7.5;Skeletal myocytes: 16.3;Syncytiotrophoblasts: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "AF22: 54.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 4.4;hippocampal formation: 5.6" HPA073684 Supported Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" 5.0 0.4 0.5 1.8 1.2 0.0 3.2 0.2 1.2 25.0 0.2 1.7 0.0 6.5 0.6 1.8 6.7 3.0 0.6 0.6 0.2 0.3 3.9 2.6 1.3 1.3 0.3 13.6 1.5 0.0 0.7 17.8 0.3 3.2 0.4 0.7 1.7 2.2 1.6 3.5 1.7 0.9 0.4 0.6 1.6 1.3 3.3 0.2 4.1 3.0 0.1 5.2 15.4 0.4 0.0 0.2 54.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.0 1.3 0.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.2 1.2 0.6 0.2 1.3 0.3 0.3 0.4 3.3 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.9 0.0 5.9 0.0 0.6 0.3 0.4 4.9 7.8 0.0 0.0 0.1 0.0 2.5 27.9 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.7 0.6 10.8 0.1 0.0 0.0 0.6 8.1 0.0 0.0 0.0 0.9 1.1 7.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 16.3 0.7 0.1 0.2 0.2 0.1 28.3 0.2 0.1 0.3 0.4 DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 30.6;Syncytiotrophoblasts: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "HPA015718: AB_1848405, HPA017281: AB_1848406" "prognostic favorable (8.96e-4)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (1.50e-3)" "unprognostic (1.43e-1)" "unprognostic (3.77e-3)" "unprognostic (3.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.45e-7)" "unprognostic (1.26e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-1)" "unprognostic (1.66e-2)" 18.8 4.2 20.2 14.5 23.3 10.0 9.9 22.3 29.5 7.8 14.6 15.2 11.7 15.7 4.7 12.0 9.5 14.6 6.7 20.4 21.2 7.9 32.8 6.0 14.9 21.7 20.6 7.5 4.5 15.1 3.9 16.9 22.3 11.8 15.9 8.3 7.5 13.8 11.3 7.4 11.0 25.5 23.1 10.6 11.9 8.6 20.9 16.1 8.0 7.5 12.2 14.8 6.2 31.0 11.2 12.6 4.6 11.5 17.6 33.5 5.9 33.9 69.0 18.6 37.8 6.7 2.3 38.3 6.0 62.1 38.0 13.6 0.9 25.3 30.5 15.7 12.2 1.2 9.2 17.1 6.3 3.4 2.1 19.6 19.8 40.8 9.7 31.8 0.3 22.7 13.4 37.7 24.1 4.0 12.4 3.1 8.6 18.4 4.6 11.4 36.2 11.5 2.6 11.2 11.8 9.5 9.7 9.2 12.7 10.6 4.3 1.1 1.3 22.1 17.0 43.0 12.0 57.7 60.2 44.0 10.4 2.2 2.0 0.1 1.8 0.1 19.3 0.9 15.5 43.4 22.3 15.5 8.6 26.9 25.6 22.2 0.5 24.2 0.6 14.1 21.9 12.3 20.2 23.3 22.3 29.5 20.4 21.2 21.7 20.6 22.3 23.1 20.9 31.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 30.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 25.3 0.7 0.0 0.0 0.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.3;prostate: 12.9;skin 1: 12.7" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 96.9;Basal respiratory cells: 56.8;Basal squamous epithelial cells: 64.3;Breast myoepithelial cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 24.1;HBEC3-KT: 13.1;hTCEpi: 38.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: AB_2684454, HPA068672: AB_2686017, HPA070955: " "unprognostic (4.65e-5)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (9.68e-4)" "unprognostic (2.87e-1)" "unprognostic (3.80e-1)" "unprognostic (4.19e-3)" "unprognostic (1.65e-1)" "unprognostic (2.65e-3)" "unprognostic (4.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (9.27e-12)" "unprognostic (7.71e-4)" "unprognostic (8.92e-2)" "unprognostic (1.55e-1)" "unprognostic (6.43e-2)" 0.8 0.5 3.8 0.7 4.5 0.9 2.9 6.9 7.0 2.9 1.8 0.4 0.4 0.6 2.0 12.3 0.6 0.3 1.7 4.4 4.2 0.5 0.7 0.5 0.9 2.7 2.6 1.1 0.8 0.1 0.8 0.6 2.7 12.9 0.0 0.6 8.1 5.2 0.2 12.7 0.6 0.1 2.6 0.7 0.4 1.0 3.5 2.3 0.7 0.0 0.9 0.8 6.7 3.2 7.9 2.8 0.8 11.3 0.0 0.6 2.5 2.8 3.0 3.1 1.4 2.7 0.4 1.5 1.7 0.5 3.8 24.1 8.0 13.1 0.7 1.5 3.0 0.6 1.5 4.2 0.8 0.5 1.6 1.3 38.5 0.9 7.1 1.0 0.0 4.5 0.7 1.1 1.2 3.0 0.6 0.6 1.0 3.0 2.9 1.6 1.4 0.7 0.4 2.6 8.3 0.8 0.9 0.3 0.4 0.6 0.7 2.4 0.8 1.1 3.6 0.8 5.6 1.8 0.4 2.5 0.1 1.1 0.8 0.3 0.1 0.1 0.1 0.0 0.8 0.1 0.5 0.5 0.0 0.2 0.2 0.1 0.2 0.8 0.1 0.5 0.0 0.1 3.8 4.5 6.9 7.0 4.4 4.2 2.7 2.6 2.7 2.6 3.5 3.2 0.3 0.0 0.5 0.3 0.4 10.1 96.9 56.8 64.3 1.3 0.6 26.7 0.6 0.0 6.0 0.0 0.0 1.3 0.5 0.0 0.0 0.1 0.3 0.1 3.0 0.7 1.2 0.0 6.1 0.0 2.7 0.4 0.0 0.2 0.0 4.7 0.0 0.0 0.1 11.8 2.8 0.0 2.0 0.0 0.4 0.5 0.3 0.6 1.8 2.8 0.0 0.6 0.0 3.0 0.9 0.1 0.0 0.0 0.1 12.9 0.0 0.0 1.1 1.2 0.0 0.5 1.1 1.7 7.0 6.7 2.6 0.3 1.3 0.4 0.0 8.3 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1651.4;salivary gland: 519.1" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 192.9;Intestinal goblet cells: 113.4;Paneth cells: 388.2;Proximal enterocytes: 167.8;Undifferentiated cells: 314.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 47.6;stomach cancer: 76.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 9.9;LHCN-M2: 16.4;RH-30: 40.3" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" NA NA 5200000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Centriolar satellite" "HPA040778: AB_2677132" "unprognostic (3.32e-2)" "unprognostic (2.17e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (7.97e-2)" "unprognostic (1.31e-1)" "unprognostic (4.51e-1)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.08e-9)" "unprognostic (2.26e-1)" "unprognostic (2.92e-4)" "unprognostic (2.00e-3)" "unprognostic (2.22e-1)" 0.5 0.2 0.6 45.3 2.9 0.1 0.3 4.4 1.5 12.8 0.0 55.6 1651.4 1.7 0.0 1.6 3.9 45.7 0.1 0.5 2.3 0.1 0.1 58.4 1.0 6.1 5.2 0.1 1.8 0.0 0.2 0.0 7.2 1.7 17.0 0.0 519.1 0.0 0.3 0.1 518.7 15.3 2.3 0.0 3.8 1.5 4.2 0.1 0.0 0.2 0.2 15.4 0.0 7.8 0.2 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.5 0.2 1.1 0.0 0.4 0.0 0.2 0.0 0.0 3.2 0.5 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 1.3 0.5 9.9 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 40.3 6.0 0.0 0.0 0.1 3.0 0.3 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.8 0.5 2.3 5.7 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 4.4 1.5 0.5 2.3 6.1 5.2 7.2 2.3 4.2 7.8 0.0 6.4 192.9 0.7 1.1 0.0 7.0 0.4 0.0 0.0 1.5 0.9 0.7 0.0 3.8 0.0 0.0 0.0 0.0 52.4 0.0 2.1 2.9 1.1 0.2 7.3 0.0 0.0 0.0 15.1 0.0 0.4 0.0 3.5 10.1 0.0 0.0 0.0 0.0 0.0 0.1 113.4 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.7 388.2 0.0 0.0 1.7 167.8 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.8 0.0 0.0 0.0 1.8 0.0 314.4 20.3 DMC1 LIM15 ENSG00000100206 "DNA meiotic recombinase 1" Q14565 22 38518948-38570204 "Predicted intracellular proteins" "Cell cycle, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.3" "Group enriched" "Detected in many" 5 "Spermatocytes: 109.3;Spermatogonia: 36.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 25.5;hTEC/SVTERT24-B: 17.4;U-266/84: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001232, CAB015397" Enhanced Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB015397: AB_629406, HPA001232: AB_1078683" "unprognostic (1.29e-2)" "unprognostic (3.11e-3)" "unprognostic (4.48e-3)" "unprognostic (5.71e-2)" "unprognostic (6.43e-2)" "unprognostic (2.22e-1)" "unprognostic (8.22e-2)" "unprognostic (2.61e-2)" "unprognostic (4.23e-2)" "unprognostic (3.99e-3)" "unprognostic (7.40e-3)" "unprognostic (1.00e-2)" "unprognostic (2.16e-4)" "unprognostic (3.94e-1)" "unprognostic (2.79e-1)" "unprognostic (7.27e-2)" "unprognostic (2.99e-1)" 0.7 0.2 0.4 1.3 0.4 2.3 0.9 1.2 0.7 1.0 0.4 0.9 0.2 2.5 0.9 0.9 0.8 0.4 2.3 0.4 0.2 0.5 0.3 0.4 2.8 0.5 0.2 1.2 0.5 0.3 0.4 0.7 0.5 1.2 1.1 0.8 0.3 0.7 1.3 1.6 0.7 0.7 0.1 0.5 0.6 12.3 0.1 3.4 0.3 0.5 3.1 0.6 0.7 0.5 7.1 2.6 5.0 0.1 0.4 2.1 0.2 7.4 1.0 11.7 8.1 0.2 0.8 3.5 0.3 2.0 0.0 1.2 2.0 0.3 13.1 25.5 0.5 13.6 2.0 0.2 0.2 1.2 2.7 0.5 0.0 17.4 0.0 0.1 0.9 11.2 10.5 3.5 4.1 3.9 2.8 10.3 9.0 3.5 0.2 6.2 0.0 5.2 1.5 0.9 9.7 0.5 12.5 1.1 0.1 1.1 2.1 2.9 0.3 0.1 0.8 0.1 0.1 9.8 21.4 6.4 2.0 2.8 0.9 0.4 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.4 0.5 0.1 0.1 0.1 0.1 0.4 0.4 1.2 0.7 0.4 0.2 0.5 0.2 0.5 0.1 0.1 0.5 0.6 0.0 2.3 3.6 0.7 2.3 1.0 0.4 1.8 0.7 2.7 2.4 2.5 0.0 2.7 3.7 0.0 1.9 0.4 1.3 1.9 0.2 2.9 0.9 0.8 0.8 0.0 11.8 1.1 0.0 1.7 1.4 0.0 1.3 1.3 1.1 0.4 0.1 1.0 0.0 1.4 1.6 0.0 0.0 1.2 3.0 1.5 1.1 0.0 1.9 0.1 4.8 1.0 2.5 0.6 0.1 0.5 1.5 3.8 0.2 0.1 0.4 0.9 0.2 13.1 1.3 0.9 109.3 36.0 0.3 0.6 0.8 0.9 0.3 2.5 0.5 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.1;Sertoli cells: 59.2;Smooth muscle cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 85.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 24.2 68.3 22.1 17.5 24.0 3.0 19.1 22.2 33.1 42.8 25.6 121.5 15.8 92.7 5.3 33.4 61.2 13.9 171.3 21.8 21.6 20.3 8.8 29.8 5.2 24.0 23.8 31.1 34.3 2.9 37.9 8.8 22.3 56.4 4.8 4.1 18.6 37.6 173.6 12.3 34.6 59.9 21.9 17.8 51.7 13.2 23.8 4.2 21.7 143.2 1.3 69.1 34.3 21.3 11.7 16.7 13.5 10.7 13.4 12.9 10.5 26.1 22.2 10.5 8.8 2.2 6.6 2.9 2.8 32.9 9.2 15.1 3.0 1.5 2.2 12.4 16.6 0.8 22.6 1.4 12.6 0.1 5.4 22.8 8.0 6.4 1.7 24.2 3.6 2.1 8.6 8.0 15.4 13.7 1.6 3.8 8.8 4.8 3.3 5.0 85.1 6.4 4.7 11.5 10.2 13.5 13.6 27.6 9.3 4.8 28.6 5.5 8.4 9.2 10.4 8.3 15.0 16.8 11.5 2.9 9.5 1.3 13.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 24.0 22.2 33.1 21.8 21.6 24.0 23.8 22.3 21.9 23.8 21.3 10.5 0.0 2.2 44.1 3.7 8.0 8.1 3.8 5.7 5.7 9.6 9.9 3.7 4.3 3.2 3.7 8.4 2.7 4.2 4.7 1.9 2.7 1.5 8.7 8.6 7.9 10.1 0.4 16.4 17.3 2.0 8.4 8.2 6.3 0.0 9.7 9.3 1.5 0.8 5.0 12.4 8.2 8.2 1.6 9.8 1.8 7.2 0.8 7.2 10.3 0.4 2.6 5.2 26.7 10.0 5.8 4.5 23.3 3.1 4.0 3.8 31.7 7.1 7.4 59.2 27.6 34.9 7.2 6.4 10.1 6.8 1.6 4.5 5.4 5.1 4.6 DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" 24.6 19.1 27.7 12.3 23.4 7.3 23.0 10.5 31.7 29.1 10.8 40.3 9.7 39.6 6.7 18.2 29.4 11.8 43.1 30.0 18.6 18.7 10.2 22.6 11.2 17.5 19.9 29.1 18.1 10.3 29.6 15.0 15.1 25.2 7.4 11.9 17.1 12.2 44.0 15.5 18.3 14.8 8.9 17.0 25.0 36.5 20.2 10.3 23.1 20.1 7.1 30.6 23.2 14.5 31.6 34.3 30.4 21.2 18.1 22.9 23.3 26.9 18.8 23.5 21.2 20.6 17.1 13.2 15.4 30.4 28.8 23.4 16.1 13.4 12.3 38.6 30.0 11.4 37.3 18.2 22.4 1.4 17.6 21.5 16.2 22.0 31.2 26.7 20.3 8.3 28.2 28.9 18.6 25.8 16.0 9.0 13.8 20.6 22.2 16.3 11.0 14.5 14.6 29.7 30.4 33.6 28.9 22.2 19.5 13.4 19.4 7.7 43.3 27.0 26.6 18.1 40.7 41.1 27.4 15.0 28.1 2.1 31.8 0.6 0.2 0.2 1.4 0.6 1.1 0.6 1.2 1.1 0.2 1.4 0.4 0.8 0.6 1.8 0.8 0.2 0.7 0.3 27.7 23.4 10.5 31.7 30.0 18.6 17.5 19.9 15.1 8.9 20.2 14.5 18.8 6.4 4.7 8.1 6.9 8.4 13.9 4.5 2.2 34.5 11.8 9.8 28.5 10.0 4.4 9.2 60.5 7.3 10.6 10.4 5.9 7.3 17.2 12.4 18.9 16.2 26.3 9.3 8.1 10.6 9.6 15.3 6.1 11.2 11.4 23.3 20.0 4.6 2.0 52.2 7.5 7.9 10.2 4.8 11.4 57.7 17.1 2.6 5.4 5.6 0.9 23.3 14.4 10.1 5.8 13.8 7.2 17.0 6.8 11.5 5.6 7.1 8.9 41.2 13.1 24.5 19.0 10.8 15.7 4.6 7.0 5.5 9.0 20.6 8.1 11.5 DMXL1 ENSG00000172869 "Dmx like 1" Q9Y485 5 119037772-119249138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 122.3;Inhibitory neurons: 147.3;Oligodendrocytes: 224.0" "Cancer enhanced" "Detected in all" "prostate cancer: 14.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036431, HPA036432" Approved Approved Nucleoli,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Cytosol "HPA036431: AB_10669791, HPA036432: AB_2675120" "unprognostic (2.47e-1)" "unprognostic (4.84e-2)" "unprognostic (7.87e-3)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-1)" "unprognostic (6.77e-2)" "unprognostic (1.40e-1)" "unprognostic (4.88e-2)" "unprognostic (5.93e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.16e-5)" "unprognostic (4.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.12e-2)" "unprognostic (5.18e-2)" 7.0 4.8 3.1 7.3 7.0 25.9 9.2 7.8 5.1 7.4 11.9 6.8 6.2 8.7 5.7 8.2 6.6 7.5 6.1 3.5 5.3 13.8 7.1 6.6 10.1 7.4 4.5 10.4 12.0 11.8 2.6 7.2 8.0 27.2 7.1 9.0 8.0 5.8 4.1 8.4 6.1 8.2 6.3 8.2 7.9 5.8 5.6 10.3 13.4 7.3 9.7 6.2 4.5 15.2 10.4 8.0 8.8 9.0 9.3 12.2 9.4 8.4 8.4 8.3 9.6 9.6 6.2 20.2 8.5 10.8 12.9 6.1 9.9 10.0 10.7 15.6 9.9 14.2 14.0 3.4 7.8 9.4 11.8 9.8 5.5 9.6 7.9 8.5 11.0 12.4 12.1 13.3 6.7 6.5 12.6 5.3 4.8 3.6 4.7 9.8 16.3 7.9 6.4 11.9 8.2 8.3 14.5 5.2 12.6 9.4 8.6 10.7 10.7 9.8 8.2 9.9 9.0 12.4 9.4 17.6 12.2 9.1 8.0 4.1 4.9 3.6 2.4 4.4 3.0 8.8 1.9 2.0 3.4 9.1 3.0 1.8 3.8 1.3 8.9 8.3 2.6 2.7 3.1 7.0 7.8 5.1 3.5 5.3 7.4 4.5 8.0 6.3 5.6 15.2 23.7 28.9 20.1 93.4 56.5 13.6 16.5 17.7 22.8 36.8 22.8 15.4 25.7 7.2 17.6 16.5 25.0 12.6 27.5 16.2 17.6 12.0 10.2 19.8 21.1 16.7 6.0 19.1 122.3 20.1 10.3 20.4 27.5 25.0 14.0 15.6 11.0 15.6 16.6 21.9 147.3 12.2 10.2 21.9 19.9 12.1 15.2 31.0 33.8 68.4 29.1 16.9 25.7 111.6 224.0 14.1 11.6 15.4 27.2 36.0 15.8 32.5 13.9 22.6 13.1 28.6 24.7 28.0 23.2 35.0 18.8 16.3 24.3 17.8 11.3 15.0 DNAJB5 Hsc40 ENSG00000137094 "DnaJ heat shock protein family (Hsp40) member B5" O75953 9 34989641-34998900 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 164.5;tongue: 218.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "myeloid DC: 5.5;neutrophil: 5.2" "Group enriched" "Detected in many" 5 "dendritic cells: 5.5;granulocytes: 5.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023818, HPA050794" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Cytosol "HPA023818: AB_1847793, HPA050794: AB_2681241" "unprognostic (1.41e-2)" "unprognostic (3.87e-1)" "unprognostic (2.53e-3)" "unprognostic (5.21e-2)" "unprognostic (1.86e-1)" "unprognostic (3.54e-2)" "unprognostic (7.31e-2)" "unprognostic (2.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.00e-2)" "unprognostic (1.31e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (4.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.00e-3)" 14.7 12.5 18.5 11.0 18.7 1.5 8.7 23.0 27.7 14.0 14.8 63.0 7.7 56.0 11.8 32.5 29.6 12.7 64.8 24.0 20.1 8.5 4.4 12.3 4.6 20.3 21.0 8.6 6.1 4.0 25.3 2.4 19.4 27.5 12.2 10.1 6.3 52.1 164.5 5.1 17.9 64.3 18.1 12.2 26.8 16.0 19.3 5.8 10.9 218.5 5.0 33.7 11.5 18.8 4.7 3.8 23.7 12.7 13.6 10.4 2.6 20.1 14.5 30.3 26.8 2.8 1.0 4.5 4.9 22.2 31.7 0.6 9.1 15.8 25.5 6.4 2.9 1.6 5.6 1.3 15.6 0.5 14.2 15.2 1.1 18.0 8.9 13.4 19.6 8.3 0.4 9.3 24.7 3.3 7.8 6.7 11.2 2.1 8.1 6.0 24.4 2.5 4.4 0.4 10.1 16.4 10.8 0.6 2.4 20.2 3.8 1.4 8.8 14.4 31.4 7.6 6.3 3.4 2.5 3.3 16.6 1.8 15.9 0.0 1.0 0.0 0.2 0.3 0.9 0.4 0.2 0.0 5.5 0.2 0.3 0.7 5.2 0.4 0.1 0.1 1.0 0.5 18.5 18.7 23.0 27.7 24.0 20.1 20.3 21.0 19.4 18.1 19.3 18.8 1.9 6.4 1.5 8.5 0.9 2.0 2.3 4.7 1.8 6.0 1.7 1.4 42.9 1.5 1.8 0.0 6.2 0.1 0.5 0.5 0.0 2.8 8.0 1.7 4.8 4.5 0.0 0.0 4.9 3.4 0.7 6.7 2.0 2.2 0.0 1.7 3.6 1.2 4.7 1.7 3.3 0.3 2.0 1.9 11.1 6.7 1.5 3.6 5.4 1.9 1.2 12.0 2.1 6.6 3.2 4.3 0.0 7.9 0.7 1.5 1.6 4.4 1.0 2.7 6.6 14.7 16.8 6.3 1.3 1.8 3.0 0.8 1.4 1.5 0.3 0.7 DNAJC15 "DNAJD1, MCJ" ENSG00000120675 "DnaJ heat shock protein family (Hsp40) member C15" Q9Y5T4 13 43023203-43114213 "Disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 462.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.12e-1)" "unprognostic (2.89e-2)" "unprognostic (1.09e-2)" "unprognostic (2.97e-2)" "unprognostic (1.53e-2)" "unprognostic (3.07e-3)" "unprognostic (3.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.38e-2)" "unprognostic (3.40e-1)" "unprognostic (2.50e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-1)" "unprognostic (5.92e-3)" "unprognostic (3.17e-1)" 5.2 7.2 13.1 5.2 13.3 3.8 5.0 13.6 23.0 6.1 9.4 7.7 8.8 3.2 1.5 4.6 3.2 4.0 10.8 12.1 14.8 9.3 7.0 5.3 6.5 14.2 13.5 1.0 4.0 6.8 3.2 5.5 14.3 3.1 6.4 4.8 4.3 8.5 6.9 3.5 8.4 4.5 16.1 4.1 4.7 3.9 15.4 5.8 6.7 6.8 5.9 4.2 2.3 15.5 0.0 0.0 2.6 2.3 9.3 13.9 1.9 10.7 10.4 12.6 6.7 12.8 11.1 8.2 0.0 13.5 6.3 7.8 1.2 9.2 13.3 17.7 0.0 7.8 5.5 9.2 10.7 0.0 5.4 14.0 17.6 6.3 6.0 6.4 10.2 4.8 0.0 1.4 10.4 4.5 0.1 2.0 0.0 9.5 0.0 3.0 2.5 12.2 19.8 4.1 3.3 3.8 0.0 5.8 8.2 4.3 4.2 11.1 10.8 5.1 2.3 8.5 2.8 0.5 1.4 0.0 11.0 0.0 5.0 5.8 4.4 2.3 2.8 4.9 2.6 5.7 3.5 3.3 8.2 4.6 2.7 3.1 0.3 3.9 4.0 5.2 4.9 3.0 13.1 13.3 13.6 23.0 12.1 14.8 14.2 13.5 14.3 16.1 15.4 15.5 82.2 83.3 49.0 16.6 111.2 42.3 23.0 59.2 53.5 25.9 73.2 80.9 166.4 100.1 71.7 132.4 25.0 76.9 58.4 192.9 115.4 271.7 462.8 172.3 77.8 83.1 133.7 98.7 16.6 329.0 291.3 72.5 63.2 289.2 39.2 13.9 71.7 238.5 140.3 30.3 22.4 147.2 63.1 143.8 104.3 124.8 15.2 130.5 88.9 22.5 159.3 50.8 64.9 25.6 17.3 274.7 241.3 12.0 148.1 20.5 263.3 342.9 72.4 26.2 26.3 71.4 92.8 279.4 117.8 90.6 45.6 92.6 70.2 16.2 176.3 38.8 DNALI1 "dJ423B22.5, hp28, P28" ENSG00000163879 "Dynein axonemal light intermediate chain 1" O14645 1 37556919-37566857 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 54.5" "Group enriched" "Detected in many" 4 "Early spermatids: 664.5;Endometrial ciliated cells: 302.8;Late spermatids: 1051.9;Respiratory ciliated cells: 484.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.3;ASC TERT1: 12.1;hTERT-RPE1: 18.8;RPTEC TERT1: 16.9;SH-SY5Y: 11.7;T-47d: 30.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028305, HPA031633" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA028305: AB_10601807, HPA031633: " "unprognostic (1.21e-2)" "unprognostic (9.04e-2)" "unprognostic (2.58e-2)" "unprognostic (6.09e-3)" "unprognostic (2.33e-1)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "prognostic favorable (6.02e-4)" "unprognostic (1.52e-1)" "unprognostic (5.50e-3)" "unprognostic (8.00e-3)" "unprognostic (3.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.19e-1)" "unprognostic (2.78e-2)" "unprognostic (1.47e-1)" "unprognostic (5.52e-2)" 2.7 6.1 14.5 0.7 14.2 0.0 7.4 14.1 15.4 9.2 27.2 5.2 1.2 8.6 14.3 2.7 54.5 9.1 3.5 13.6 17.8 12.2 12.0 10.5 0.8 18.3 22.1 13.9 9.1 9.1 12.6 1.6 18.6 6.7 2.3 11.8 4.5 7.2 1.1 0.7 2.3 4.1 17.3 1.0 6.4 29.4 16.5 0.7 10.7 1.3 0.6 3.8 2.0 17.9 0.0 0.0 14.3 1.3 2.9 12.1 0.2 1.8 3.9 0.1 0.5 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.3 9.3 0.0 0.1 5.5 0.0 9.3 0.0 18.8 1.5 0.0 1.0 0.0 7.5 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.9 0.0 16.9 0.0 1.6 11.7 0.0 0.0 0.0 2.2 30.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 14.2 14.1 15.4 13.6 17.8 18.3 22.1 18.6 17.3 16.5 17.9 1.9 19.2 32.4 6.8 1.0 0.9 22.6 42.3 1.2 2.7 19.6 15.9 5.6 21.5 48.5 20.2 8.4 2.7 0.3 0.8 29.4 34.0 664.5 302.8 12.2 4.7 20.9 0.0 2.6 10.2 8.5 15.7 20.4 16.7 2.5 38.9 8.6 9.4 2.8 3.3 2.8 11.5 46.8 0.6 0.6 1051.9 13.7 2.0 0.0 0.0 0.0 18.7 0.0 3.0 1.7 12.5 1.0 12.0 0.0 21.0 1.0 43.3 484.1 19.6 6.6 17.5 18.5 140.0 18.5 0.3 0.6 3.4 1.1 21.0 4.9 9.3 DOCK3 "KIAA0299, MOCA, PBP" ENSG00000088538 "Dedicator of cytokinesis 3" Q8IZD9 3 50674927-51384198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.5;thyroid gland: 12.2" "Group enriched" "Detected in some" 11 "Astrocytes: 223.6;Excitatory neurons: 777.2;Inhibitory neurons: 837.1;Oligodendrocyte precursor cells: 445.4;Oligodendrocytes: 814.7" "Group enriched" "Detected in many" 4 "glioma: 2.7;thyroid cancer: 7.6" "Group enriched" "Detected in many" 8 "amygdala: 9.9;basal ganglia: 12.8;cerebral cortex: 17.5;hippocampal formation: 13.4;white matter: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.1;GAMG: 5.9;HMC-1: 4.9;JURKAT: 5.8;U-87 MG: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037543, HPA037544" Enhanced Supported Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA037543: AB_10672495, HPA037544: AB_10670383" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-3)" "unprognostic (6.35e-8)" "unprognostic (2.63e-1)" "unprognostic (3.02e-2)" "unprognostic (4.64e-2)" "unprognostic (3.67e-1)" "unprognostic (1.91e-1)" "unprognostic (7.99e-2)" "unprognostic (2.36e-3)" "unprognostic (1.34e-2)" "unprognostic (1.45e-2)" "unprognostic (5.83e-5)" "unprognostic (7.96e-2)" "unprognostic (6.19e-2)" "unprognostic (1.24e-1)" 0.8 3.3 9.9 0.2 12.8 0.2 0.3 0.9 17.5 0.9 0.0 3.1 0.2 0.7 0.7 2.1 0.8 0.3 2.9 13.4 0.8 0.8 0.1 0.5 0.3 1.3 0.4 0.4 0.4 5.3 6.4 0.1 1.2 2.0 0.3 10.1 1.5 1.9 1.9 2.4 0.8 1.0 0.0 0.5 1.4 5.9 1.7 0.0 12.2 1.8 0.3 2.0 0.6 17.2 0.1 0.2 0.2 6.1 0.0 0.0 2.6 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.5 1.9 5.9 0.4 4.1 0.0 0.1 3.7 4.3 0.1 1.2 0.1 0.0 0.1 4.9 0.0 0.1 0.2 0.0 0.3 0.0 5.8 0.0 0.1 0.5 0.2 0.0 0.0 2.0 0.3 1.9 0.0 0.6 0.0 0.3 0.6 3.7 0.0 0.3 3.4 0.0 4.1 0.1 0.0 0.4 0.2 1.6 0.2 2.2 0.3 0.0 0.0 7.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 9.9 12.8 0.9 17.5 13.4 0.8 1.3 0.4 1.2 0.0 1.7 17.2 0.0 0.0 0.6 223.6 0.0 0.0 0.2 0.0 0.0 22.0 0.3 0.4 7.5 0.0 0.7 0.0 2.1 0.1 0.4 0.1 1.9 0.0 11.4 0.3 0.2 0.4 0.0 0.0 777.2 0.0 0.2 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 33.7 837.1 0.0 0.0 0.0 0.0 6.0 0.0 0.4 0.0 52.5 0.0 3.1 1.0 445.4 814.7 0.3 0.0 0.0 0.5 0.1 0.0 0.2 0.1 5.1 0.0 1.1 1.2 6.0 4.1 0.4 0.1 0.0 1.1 0.1 0.0 0.1 DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 216.7" "Cell type enhanced" "Detected in many" "Adipocytes: 158.7;Excitatory neurons: 150.6;Inhibitory neurons: 202.2;Microglial cells: 148.0;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 402.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 2.0;MAIT T-cell: 4.8;memory CD4 T-cell: 5.2;memory CD8 T-cell: 2.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.0;NK-cell: 7.3;T-reg: 2.4" "Group enriched" "Detected in many" 11 "NK-cells: 7.3;T-cells: 6.0" "Cell line enhanced" "Detected in many" "BEWO: 200.8;hTERT-HME1: 435.4;HUVEC TERT2: 180.9;TIME: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB034061: AB_2277513, CAB034065: AB_2094798, HPA043940: AB_2678741" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (8.76e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (2.79e-1)" "unprognostic (7.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.36e-2)" "unprognostic (3.31e-2)" 83.2 22.4 82.6 21.4 137.2 6.0 71.1 96.6 91.0 42.9 30.8 44.4 15.7 31.3 35.5 93.1 30.3 36.6 58.9 72.8 93.8 21.9 15.8 93.0 33.8 116.6 112.1 27.4 19.9 41.8 21.1 98.2 123.4 23.0 20.8 39.5 51.2 21.7 25.9 76.9 35.2 36.9 86.6 16.8 24.7 16.2 110.4 47.8 62.6 64.3 40.4 29.0 49.6 216.7 61.6 19.4 10.6 14.2 10.6 8.3 200.8 17.2 14.2 12.1 10.7 127.4 47.7 51.3 39.8 16.6 21.8 59.5 27.4 54.3 21.8 52.2 15.2 0.0 37.6 2.1 14.0 0.1 2.9 9.0 37.2 12.4 435.4 27.9 180.9 33.0 10.6 11.6 52.1 20.2 35.5 0.3 4.9 84.6 14.2 2.1 39.3 2.7 38.3 50.8 22.4 24.3 26.4 63.4 15.7 85.9 16.9 0.4 179.7 9.7 11.4 6.5 28.5 17.6 14.8 8.6 15.6 0.0 16.0 0.0 0.0 0.0 2.0 0.0 4.8 0.6 5.2 2.1 0.0 0.2 6.0 4.0 0.1 7.3 0.0 0.0 2.4 1.5 82.6 137.2 96.6 91.0 72.8 93.8 116.6 112.1 123.4 86.6 110.4 216.7 158.7 16.0 39.5 37.5 3.4 15.3 7.1 14.7 10.2 37.9 15.4 6.5 9.4 11.5 12.5 9.2 50.1 35.6 7.0 11.9 1.9 5.4 1.7 10.5 5.3 90.2 6.7 3.6 150.6 6.6 8.3 17.2 2.6 21.4 2.5 18.0 47.8 8.4 5.0 25.2 202.2 6.0 10.2 1.9 7.4 3.3 7.8 1.7 1.8 148.0 0.4 12.9 4.1 238.8 402.2 14.7 5.6 14.7 2.8 10.1 10.6 3.8 7.1 23.9 0.0 122.6 12.4 7.2 5.4 25.6 32.0 17.2 11.0 2.4 5.9 10.5 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 110.7;Distal tubular cells: 39.2;Excitatory neurons: 49.7;Horizontal cells: 38.7;Inhibitory neurons: 79.6;Muller glia cells: 63.9;Oligodendrocyte precursor cells: 58.3" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 32.9;ASC diff: 13.1;ASC TERT1: 11.0;hTEC/SVTERT24-B: 13.7;U-138 MG: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 2.9 1.9 14.6 1.7 14.2 0.0 1.9 13.4 15.6 1.1 13.0 1.4 0.3 1.7 0.3 1.7 12.2 9.8 18.4 15.4 16.9 5.2 2.3 1.0 0.6 15.9 14.7 0.9 1.2 0.2 1.1 1.8 18.6 0.9 0.7 11.7 1.4 0.8 46.0 0.5 0.7 2.8 13.9 0.3 0.8 1.7 15.3 0.4 5.1 24.3 0.4 4.7 0.9 13.3 0.0 0.0 32.9 0.0 13.1 11.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 4.3 0.0 13.7 0.0 0.6 1.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 3.6 7.0 0.0 8.6 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.0 51.3 3.2 1.4 0.0 0.0 0.0 0.1 2.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 14.2 13.4 15.6 15.4 16.9 15.9 14.7 18.6 13.9 15.3 13.3 4.8 0.0 0.0 110.7 0.3 0.3 2.3 0.0 0.0 12.3 6.7 6.2 7.3 12.8 0.0 11.0 6.2 0.3 0.1 0.0 39.2 17.7 2.3 0.4 1.5 3.3 0.0 0.0 49.7 1.2 0.6 14.4 0.0 10.6 0.0 28.6 17.5 0.0 29.0 38.7 79.6 0.0 0.0 0.6 2.5 4.5 2.5 0.6 0.0 9.4 14.5 63.9 0.0 58.3 2.1 2.2 0.0 1.2 0.1 2.0 0.0 0.2 0.0 8.1 0.0 2.8 5.3 3.7 1.5 0.0 0.4 0.8 0.2 1.6 0.0 0.9 DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 230.4;Excitatory neurons: 236.8;Inhibitory neurons: 259.1;Oligodendrocyte precursor cells: 178.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.5;Hep G2: 11.1;RPMI-8226: 10.5;SCLC-21H: 4.7;SH-SY5Y: 10.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" 1.1 0.7 8.8 0.7 10.3 0.1 0.5 0.9 14.0 1.8 0.0 0.6 0.3 1.5 0.5 0.7 0.7 3.2 6.2 17.8 10.6 4.9 2.4 2.4 0.5 10.9 11.6 2.2 0.2 12.5 0.7 5.9 9.7 1.3 0.5 22.3 0.8 2.1 0.1 0.5 0.5 2.5 4.1 0.9 0.7 1.5 6.5 0.1 2.2 0.6 0.5 3.1 1.1 5.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.0 11.1 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 10.5 0.0 0.0 4.7 10.5 0.0 0.0 0.0 7.6 0.0 0.0 0.0 4.0 0.6 0.0 1.5 0.3 0.0 0.0 3.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.3 0.9 14.0 17.8 10.6 10.9 11.6 9.7 4.1 6.5 5.8 0.5 0.0 0.0 9.8 0.0 0.3 0.1 0.0 0.0 230.4 0.1 0.0 9.1 0.0 1.3 0.0 14.6 0.0 1.2 0.0 1.9 0.0 45.3 0.4 13.3 1.5 0.0 0.0 236.8 0.0 0.0 6.7 0.0 0.3 0.0 17.2 0.0 0.9 0.0 10.1 259.1 0.0 0.0 0.3 0.8 30.6 1.5 2.1 0.0 8.4 0.1 6.9 2.1 178.4 6.4 0.0 0.0 6.8 0.7 0.1 0.0 9.6 0.0 14.6 0.0 0.4 5.5 0.9 1.1 0.1 0.6 0.0 1.2 4.9 0.0 0.1 DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.2;dendritic cells: 3.8;Extravillous trophoblasts: 11.4;Hofbauer cells: 16.7;Syncytiotrophoblasts: 8.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Mitochondria "HPA072065: AB_2686486" "prognostic unfavorable (7.08e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.36e-1)" "unprognostic (3.13e-2)" "unprognostic (4.35e-2)" "unprognostic (3.01e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" 3.5 1.7 2.9 5.6 4.8 24.2 5.8 19.8 8.0 4.6 0.0 15.4 12.6 2.3 3.0 11.8 4.2 4.1 4.5 3.6 1.0 3.2 9.1 4.9 4.7 3.6 1.1 1.6 4.6 30.4 2.3 3.1 4.5 12.1 15.1 1.6 19.3 3.4 15.9 7.1 11.7 3.8 0.1 5.5 20.5 3.5 2.1 6.5 4.0 13.5 6.3 4.0 5.9 3.4 25.9 5.4 4.0 6.8 4.4 8.4 38.2 12.0 14.2 16.7 10.4 3.8 2.0 4.8 1.8 9.0 12.7 5.2 7.8 2.8 13.5 8.8 7.0 11.0 1.2 1.4 3.9 10.8 5.5 2.9 5.5 10.9 2.9 10.0 7.1 11.2 3.5 7.6 5.0 29.0 8.7 11.1 3.3 30.4 5.6 15.4 2.3 23.7 8.8 10.2 10.7 6.1 8.0 35.9 10.1 5.5 13.1 13.2 12.2 6.4 1.7 8.4 9.8 5.7 15.0 2.2 9.2 23.0 3.7 1.0 3.0 6.1 2.6 2.7 1.4 7.3 1.7 1.5 1.9 10.5 1.1 0.9 4.8 1.0 2.4 5.9 1.4 1.4 2.9 4.8 19.8 8.0 3.6 1.0 3.6 1.1 4.5 0.1 2.1 3.4 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.9 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 11.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 0.0 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.3;Proximal enterocytes: 291.1;Proximal tubular cells: 101.4;Syncytiotrophoblasts: 172.0" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Cell line enhanced" "Detected in many" "ASC diff: 194.4;ASC TERT1: 212.6;BJ hTERT+: 207.0;RPTEC TERT1: 263.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 13.3 3.1 0.2 5.3 0.2 0.6 8.4 0.1 0.6 10.9 0.1 14.6 107.0 3.6 4.0 3.0 7.4 6.7 3.4 0.2 0.1 94.9 57.2 16.0 5.8 0.2 0.2 3.5 3.5 155.7 0.1 134.1 0.3 107.3 16.9 0.1 84.5 23.5 1.5 5.7 137.9 3.0 0.1 11.2 7.6 1.3 0.8 12.4 5.0 3.9 4.4 5.7 3.5 0.4 0.2 0.2 1.0 0.0 194.4 212.6 0.6 37.7 207.0 10.9 37.2 38.0 1.0 0.0 13.6 71.0 30.2 1.1 0.4 0.0 6.2 12.3 0.0 0.0 0.0 57.1 77.0 0.0 0.0 22.0 0.1 66.3 0.5 9.1 6.6 0.7 0.0 0.0 3.6 0.0 3.6 0.5 2.0 1.3 72.7 0.0 0.0 0.6 263.3 0.0 0.1 0.4 0.0 0.0 0.0 4.4 0.0 0.3 37.0 21.8 1.1 0.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 6.6 0.0 52.3 0.2 16.2 10.7 1.2 0.0 15.7 6.6 0.4 5.3 0.0 4.0 2.0 4.7 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.2 0.3 0.1 0.8 0.4 10.8 6.4 26.0 0.3 2.1 4.1 0.4 0.1 0.0 1.8 0.2 0.8 3.3 12.8 2.8 14.7 10.4 140.3 10.4 27.4 1.9 3.0 15.0 2.3 7.1 9.4 55.2 0.4 31.6 0.0 59.1 35.3 2.0 68.0 13.9 5.3 9.3 34.5 14.5 0.0 6.3 16.4 0.0 0.9 7.6 7.9 0.0 4.8 5.4 3.7 1.1 0.0 1.0 2.5 0.7 1.4 23.8 0.0 2.1 32.7 291.1 101.4 2.2 0.1 0.0 2.1 1.5 4.0 1.1 0.1 4.1 172.0 25.8 29.2 29.1 0.3 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 199.6;liver: 477.6" "Group enriched" "Detected in some" 12 "Hepatocytes: 459.5;Proximal tubular cells: 518.8" "Cancer enriched" "Detected in some" 5 "liver cancer: 57.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024785, HPA070814" Enhanced NA NA 820000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024785: AB_1847856, HPA070814: " "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 8.6 2.8 0.6 0.1 0.6 0.0 0.4 0.2 1.7 1.2 0.2 0.2 0.0 0.1 0.6 0.1 0.7 6.5 0.1 0.6 0.5 199.6 477.6 0.6 0.3 0.5 0.7 0.2 0.1 0.6 0.2 0.6 0.6 4.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.9 1.2 5.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.2 1.7 0.6 0.5 0.5 0.7 0.6 0.3 1.2 0.5 0.1 0.0 0.0 1.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 40.0 0.0 20.2 0.0 0.0 0.0 0.0 27.4 0.1 12.8 0.3 0.1 1.0 0.0 16.0 11.2 0.0 0.0 1.8 0.0 0.3 0.0 0.4 11.7 459.5 1.4 0.0 4.6 0.0 0.0 11.1 0.3 13.5 0.9 10.6 0.0 14.0 0.4 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 518.8 0.0 0.1 0.0 0.0 0.0 1.2 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 101.5;Cone photoreceptor cells: 331.5;Granulosa cells: 261.9;Peritubular cells: 205.7;Rod photoreceptor cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 109.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 685.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 740000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA010948: AB_1847245" "unprognostic (3.92e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-3)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (5.99e-2)" "unprognostic (6.92e-2)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.87e-9)" "unprognostic (1.14e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.23e-4)" 58.4 18.6 63.4 54.4 68.6 0.8 37.5 60.3 55.8 66.1 30.4 142.1 18.4 119.9 73.9 69.0 63.4 65.1 59.2 57.0 116.0 7.7 4.4 45.2 18.1 123.7 94.2 88.0 5.5 2.7 12.7 19.8 81.8 104.6 37.6 163.8 24.5 162.0 68.7 23.8 43.3 217.6 115.2 26.4 40.9 19.9 95.2 7.1 22.4 36.0 27.0 118.0 50.6 105.1 0.5 36.1 63.9 0.1 2.3 63.3 1.6 34.1 163.0 71.4 94.4 114.5 3.1 0.0 9.6 100.1 37.4 3.7 13.1 1.4 79.1 16.3 29.2 0.1 30.0 0.2 63.1 0.3 0.2 12.2 0.6 153.8 60.3 178.7 206.9 0.0 0.0 1.3 41.1 0.3 0.2 0.6 135.9 0.2 53.7 0.2 135.1 0.5 63.0 14.2 47.1 685.4 0.3 0.3 10.8 87.9 0.5 1.0 91.1 51.6 38.5 127.0 127.3 113.9 21.7 0.2 47.5 1.4 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.4 68.6 60.3 55.8 57.0 116.0 123.7 94.2 81.8 115.2 95.2 105.1 59.9 0.0 2.8 101.5 0.0 9.4 3.4 1.5 2.2 14.2 8.1 6.6 7.8 1.5 4.0 0.0 331.5 0.1 0.0 0.2 0.0 9.1 16.8 0.3 4.6 62.6 6.6 0.0 11.3 8.4 0.3 79.8 3.1 1.2 1.3 261.9 57.8 0.4 1.6 5.0 12.9 0.2 24.4 1.2 11.9 19.2 42.9 3.1 19.6 5.6 0.0 28.3 0.0 83.9 0.7 13.7 0.0 205.7 0.3 10.1 0.0 0.1 2.8 125.0 0.0 23.6 40.9 1.8 3.2 3.7 8.2 0.4 1.5 49.6 0.3 4.5 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 16.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 17.3;Gastric mucus-secreting cells: 13.7;Intestinal goblet cells: 17.3;Paneth cells: 13.9;Proximal enterocytes: 44.2;Undifferentiated cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 5.8;Hep G2: 18.4;hTCEpi: 6.1;OE19: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.0 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.2 0.4 0.0 6.3 16.4 0.0 0.0 1.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 5.6 0.0 0.4 0.0 0.0 1.1 13.9 0.5 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 1.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.1 5.8 0.1 0.0 0.0 0.5 0.2 18.4 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 15.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 2.4 0.0 0.9 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.5 0.1 4.5 4.6 0.4 0.1 0.0 0.3 1.5 3.5 0.0 2.1 1.6 0.0 17.3 0.0 0.0 0.0 0.2 0.1 0.0 2.4 0.0 0.6 0.0 0.8 0.6 13.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 17.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 13.9 0.0 0.4 0.0 44.2 0.0 5.0 0.9 0.0 0.1 0.1 0.6 0.3 3.1 0.0 1.1 0.1 0.0 12.5 0.2 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSCAML1 KIAA1132 ENSG00000177103 "DS cell adhesion molecule like 1" Q8TD84 11 117427772-117817525 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.0;retina: 20.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 87.9;Excitatory neurons: 178.8;Inhibitory neurons: 232.4;Oligodendrocyte precursor cells: 352.8;Oligodendrocytes: 465.3;Rod photoreceptor cells: 137.7" "Cancer enhanced" "Detected in some" "glioma: 1.9;renal cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.6;HDLM-2: 1.7;RPTEC TERT1: 4.8;T-47d: 9.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035230 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035230: AB_2674527" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" "unprognostic (1.07e-2)" "unprognostic (6.27e-5)" "unprognostic (8.48e-2)" "unprognostic (1.56e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (7.96e-2)" "unprognostic (2.89e-2)" "unprognostic (2.39e-3)" "unprognostic (8.37e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-2)" 1.5 0.3 8.4 0.1 12.6 0.2 0.4 4.3 12.4 1.0 0.0 2.0 0.4 2.0 0.5 0.2 2.7 1.2 1.0 11.0 10.2 3.0 0.4 0.7 0.3 13.2 12.7 5.0 0.9 0.0 4.3 0.1 12.3 0.8 0.6 20.1 1.1 0.3 0.5 0.2 0.7 0.8 2.9 1.0 0.7 2.1 14.9 0.5 0.7 0.3 0.4 1.2 0.7 27.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.9 0.1 0.0 0.0 0.0 0.3 9.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 8.4 12.6 4.3 12.4 11.0 10.2 13.2 12.7 12.3 2.9 14.9 27.0 0.4 0.0 0.0 23.8 0.1 0.1 0.1 0.1 0.6 87.9 0.0 0.0 2.7 4.3 0.1 0.0 41.7 0.0 0.0 0.3 0.0 0.4 6.1 2.1 0.3 0.7 6.7 0.0 178.8 0.0 0.0 1.3 0.0 0.4 0.0 0.2 0.7 0.0 0.1 3.3 232.4 3.7 0.0 0.0 1.2 10.5 1.2 0.2 0.0 3.7 0.0 4.0 0.0 352.8 465.3 0.0 0.1 1.9 0.0 0.2 0.0 1.8 5.5 137.7 0.0 1.2 1.2 0.3 0.8 0.0 0.0 0.1 0.3 0.1 0.9 0.1 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 313.9;vagina: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 197.6;Basal squamous epithelial cells: 101.9;Squamous epithelial cells: 470.6;Suprabasal keratinocytes: 206.4;Urothelial cells: 87.2" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.2" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.2" "Group enriched" "Detected in some" 7 "HaCaT: 204.4;hTCEpi: 494.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" 0.3 0.0 0.1 0.2 0.1 0.2 3.9 0.1 0.2 71.1 0.1 0.0 5.4 0.0 0.0 313.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.4 0.1 0.0 43.6 0.0 0.1 39.9 3.9 0.0 0.0 0.0 0.2 0.1 0.2 14.8 0.0 0.0 72.7 1.2 119.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 204.4 0.0 46.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 494.7 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 28.9 18.5 0.0 0.2 197.6 17.4 32.2 101.9 0.3 0.5 5.0 0.3 0.0 21.1 0.0 0.0 0.4 1.5 0.2 0.0 0.2 0.6 0.1 0.3 2.7 0.0 0.0 2.7 0.4 0.4 2.2 0.0 0.1 12.6 0.0 0.4 0.3 0.4 0.0 0.1 1.3 2.0 0.3 7.7 0.5 0.0 3.2 7.2 0.0 0.7 0.1 0.0 0.0 0.1 1.3 2.5 0.7 1.2 12.3 7.1 0.1 15.9 0.8 6.6 0.0 1.8 3.3 2.8 470.6 206.4 0.3 1.3 0.0 6.5 87.2 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DSTN "ACTDP, ADF" ENSG00000125868 "Destrin, actin depolymerizing factor" P60981 20 17570075-17609919 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 1690.3;SK-BR-3: 1421.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037094 Approved NA NA 3700000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" "CAB037094: AB_476911" "unprognostic (1.05e-3)" "unprognostic (1.61e-2)" "unprognostic (7.04e-2)" "unprognostic (2.20e-2)" "unprognostic (2.27e-1)" "unprognostic (1.51e-2)" "unprognostic (5.61e-3)" "unprognostic (1.74e-1)" "unprognostic (1.27e-1)" "unprognostic (8.18e-2)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (2.89e-3)" "unprognostic (6.05e-2)" "unprognostic (9.04e-2)" "unprognostic (5.56e-2)" "unprognostic (2.71e-3)" 306.9 232.5 134.0 136.7 150.8 53.3 287.0 144.0 178.0 336.8 144.5 1146.3 136.1 636.1 297.1 535.6 449.9 297.4 411.6 150.0 158.2 269.0 141.3 315.8 60.2 146.7 150.3 236.8 268.9 180.0 127.1 162.3 154.4 559.2 306.8 114.0 274.6 758.3 87.2 227.8 285.6 695.0 147.6 75.2 486.8 82.0 140.4 47.8 273.0 111.4 79.0 704.4 312.7 164.1 323.0 431.3 161.5 160.5 399.8 391.5 303.8 397.7 616.4 248.1 221.7 200.4 348.6 50.1 97.7 587.8 458.5 305.3 149.4 606.5 281.9 28.0 125.5 131.9 247.2 295.3 426.2 102.9 86.5 357.9 563.1 239.3 275.9 609.0 360.6 85.4 63.4 65.7 468.1 251.7 42.2 121.6 110.4 1690.3 322.3 28.9 248.4 103.5 686.4 291.9 244.6 72.9 363.0 1421.1 441.9 263.7 654.3 55.9 345.3 294.9 93.2 324.1 276.8 39.7 52.2 134.6 139.9 43.8 250.8 33.8 17.6 59.2 55.9 32.2 46.8 11.9 56.9 52.0 22.1 9.0 37.0 47.0 11.8 48.8 46.4 51.1 46.7 45.3 134.0 150.8 144.0 178.0 150.0 158.2 146.7 150.3 154.4 147.6 140.4 164.1 372.8 1442.3 667.9 25.1 84.9 1151.6 697.0 796.7 542.4 101.5 925.2 762.2 1131.3 739.2 696.8 678.6 50.1 576.4 336.9 549.2 1457.6 1022.2 295.0 558.3 447.3 481.7 546.5 83.1 54.7 1468.6 1165.0 533.5 275.7 540.2 183.8 199.4 425.9 602.4 222.2 176.7 43.1 643.2 533.0 147.8 361.5 111.2 496.8 133.0 610.1 57.1 191.7 779.1 224.6 30.7 44.0 1018.6 572.8 1266.8 172.4 640.3 304.4 1491.4 912.0 153.1 1216.2 271.1 1745.4 390.0 298.9 515.2 1043.5 549.5 161.6 252.0 545.8 680.2 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSG00000140279 "Dual oxidase 2" Q9NRD8 15 45092650-45114172 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 290.2;thyroid gland: 75.7;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 159.3;Ductal cells: 225.2;Exocrine glandular cells: 125.5;Gastric mucus-secreting cells: 85.1;Pancreatic endocrine cells: 411.7;Urothelial cells: 110.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 60.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HaCaT: 6.3" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (3.19e-1)" "unprognostic (7.51e-2)" "unprognostic (3.77e-2)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (7.93e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (9.59e-3)" "unprognostic (7.11e-2)" "unprognostic (5.32e-5)" "unprognostic (1.71e-1)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" "unprognostic (1.63e-2)" 0.5 1.4 0.0 21.5 0.1 0.0 0.6 0.1 0.3 2.8 0.0 11.6 1.5 0.2 3.1 21.5 0.5 290.2 0.8 0.1 0.1 0.7 0.8 2.5 0.1 0.2 0.6 0.5 1.2 0.2 0.1 0.0 0.1 11.8 5.5 0.0 4.6 1.9 0.0 4.9 8.3 2.7 0.1 0.0 42.3 1.4 0.1 0.0 75.7 0.0 4.2 92.8 21.7 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 6.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.3 0.1 48.1 36.9 0.0 3.0 1.9 5.2 11.7 1.8 0.4 0.6 0.6 1.9 54.3 31.5 0.0 0.0 0.1 0.0 159.3 0.0 225.2 0.6 1.0 0.5 5.6 1.2 0.0 0.1 125.5 0.0 5.1 85.1 3.5 32.8 0.1 0.4 0.1 0.1 0.0 0.1 10.1 4.1 0.0 0.4 0.3 0.3 3.9 0.0 0.0 5.2 0.2 0.0 0.0 0.1 411.7 45.5 0.0 0.8 4.5 2.9 0.0 43.4 0.3 0.0 0.2 2.7 0.9 1.0 3.6 1.8 0.0 4.6 0.1 34.7 110.4 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12473282-12562863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 114.9;Oligodendrocytes: 196.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.9" "Lineage enriched" "Detected in single" 5 "T-cells: 3.9" "Cell line enhanced" "Detected in many" "NTERA-2: 37.7;RT4: 34.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favorable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 9.3 47.8 4.9 7.8 8.3 3.6 15.0 7.7 5.3 12.2 6.3 11.3 13.6 11.3 6.2 12.7 10.5 8.0 7.2 4.8 6.0 7.6 33.3 12.0 6.4 7.3 8.1 10.7 18.8 8.0 12.9 5.5 6.2 19.7 10.9 7.5 14.6 3.4 11.3 11.1 13.1 4.9 5.4 6.8 13.2 7.1 6.7 15.2 8.8 4.7 9.0 10.7 17.0 11.8 4.5 6.5 7.6 4.2 2.8 3.3 13.6 2.6 5.8 6.4 9.1 18.1 8.6 0.4 1.4 2.9 11.3 2.9 14.1 2.4 8.6 14.4 7.0 0.7 6.8 19.2 5.4 1.3 3.0 2.8 6.7 5.1 16.3 6.8 5.0 7.3 4.0 11.8 0.4 8.6 1.7 0.9 37.7 11.1 1.9 2.0 2.6 8.6 3.6 34.3 12.3 11.5 10.6 13.6 6.7 28.2 5.5 2.2 4.5 2.9 8.3 1.8 2.9 8.3 10.6 1.5 3.8 2.9 4.0 0.0 0.0 0.0 0.5 0.0 2.3 0.0 1.6 0.7 0.1 0.0 0.5 0.3 0.8 0.0 0.0 0.0 3.9 0.3 4.9 8.3 7.7 5.3 4.8 6.0 7.3 8.1 6.2 5.4 6.7 11.8 9.6 28.9 55.5 30.3 3.3 2.8 14.9 1.5 3.4 4.8 23.8 13.1 11.5 20.0 9.7 3.7 2.1 10.5 5.6 35.7 0.0 14.3 1.3 15.1 10.2 9.2 49.6 0.0 19.5 24.6 4.1 9.9 11.7 19.9 23.5 114.9 7.5 34.2 5.3 6.7 24.8 10.0 2.0 9.4 1.9 2.3 5.9 5.7 5.4 38.4 2.9 36.8 0.0 56.3 196.3 20.9 25.3 6.8 4.3 34.3 25.4 5.2 10.4 4.8 0.0 11.1 10.3 3.0 5.8 6.2 1.8 30.1 27.9 9.9 18.7 24.5 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766125-43778977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 274.3;Late spermatids: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 9 "dendritic cells: 33.5;granulocytes: 11.0;monocytes: 29.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol NA NA 1300000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA063616: AB_2685061" "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favorable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 39.8 43.2 63.6 21.6 67.1 9.9 32.7 57.2 91.0 32.4 59.6 96.1 27.8 49.2 31.1 48.4 33.6 33.4 194.8 69.0 65.4 72.0 108.1 50.2 14.3 64.2 64.3 18.2 48.6 47.0 33.1 31.4 64.4 57.7 26.0 30.8 31.8 72.9 261.9 24.6 38.7 62.9 58.5 40.7 57.5 24.5 65.6 6.2 30.5 213.7 13.0 63.1 33.6 64.3 32.3 57.1 21.5 23.1 61.1 32.7 18.3 23.8 56.4 54.4 65.1 55.4 21.1 4.9 36.7 44.7 112.4 27.3 33.7 29.3 56.9 11.1 25.6 16.2 25.9 45.4 74.5 2.0 16.1 30.5 51.5 42.0 36.2 59.0 38.5 15.9 14.7 5.4 64.2 23.1 8.5 8.4 9.9 45.5 41.1 10.5 64.5 12.1 75.8 33.3 12.0 21.6 27.9 18.3 71.8 58.8 82.2 44.7 40.4 61.1 41.5 87.9 40.1 28.5 40.4 1.2 72.4 22.6 20.8 11.0 29.3 6.4 1.5 15.0 2.7 2.6 2.4 1.9 33.5 2.4 1.9 1.7 7.0 1.7 20.6 13.8 1.6 11.4 63.6 67.1 57.2 91.0 69.0 65.4 64.2 64.3 64.4 58.5 65.6 64.3 23.1 25.6 21.2 6.5 9.2 22.4 47.6 17.6 10.8 17.2 20.3 21.3 274.3 54.3 17.9 42.3 25.0 16.3 9.5 36.9 41.1 47.8 88.6 18.8 16.6 33.8 36.4 11.6 18.1 58.9 21.8 25.9 42.8 25.0 38.7 6.1 25.4 108.8 86.6 20.2 15.5 19.9 24.4 49.1 52.0 160.5 14.6 47.2 10.6 15.9 53.9 16.8 4.1 8.5 13.8 56.5 32.3 26.4 8.0 46.2 57.7 87.6 21.1 17.3 32.9 24.1 28.4 3.3 5.0 16.0 28.8 45.0 6.3 15.1 18.0 42.6 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EAF2 "BM040, TRAITS, U19" ENSG00000145088 "ELL associated factor 2" Q96CJ1 3 121835183-121886526 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.8;lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "B-cells: 73.7;Plasma cells: 144.1;Proximal tubular cells: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 104.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.5;HL-60: 114.9;THP-1: 59.9;U-698: 93.5;U-937: 64.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA008411 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA008411: AB_1847950" "unprognostic (3.43e-1)" "prognostic favorable (2.25e-9)" "unprognostic (1.48e-1)" "prognostic favorable (2.66e-4)" "unprognostic (1.00e-1)" "unprognostic (3.18e-2)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" "unprognostic (9.04e-2)" "unprognostic (8.34e-2)" 4.3 2.6 2.3 19.5 2.0 71.8 10.0 2.1 3.1 5.5 1.5 10.3 8.9 2.0 4.9 2.7 1.4 5.0 1.7 2.7 2.4 30.2 3.5 4.3 53.6 2.1 2.4 1.0 4.2 3.1 3.3 2.9 2.2 21.0 11.6 1.7 7.6 8.4 0.8 1.0 7.7 3.5 1.4 16.9 8.2 4.6 3.0 7.7 1.7 1.3 43.4 7.8 1.4 2.0 3.5 3.0 2.0 2.5 0.7 2.1 6.0 1.3 0.8 2.4 4.4 5.8 2.0 73.5 1.5 0.3 7.7 5.7 5.0 3.0 6.0 35.8 2.9 42.4 3.0 11.1 1.0 114.9 44.7 1.0 6.9 2.8 2.6 0.0 2.3 10.0 5.0 14.2 1.1 1.0 16.3 15.1 2.9 13.8 2.5 17.1 6.4 11.2 2.4 4.3 2.5 0.6 2.1 2.0 5.7 5.5 1.8 59.9 0.7 1.5 2.4 1.4 3.4 25.4 12.2 93.5 2.8 64.0 4.7 11.9 18.8 42.8 1.4 41.2 2.8 104.4 2.2 1.5 22.5 97.4 2.9 1.6 3.5 1.8 54.7 30.5 2.7 13.1 2.3 2.0 2.1 3.1 2.7 2.4 2.1 2.4 2.2 1.4 3.0 2.0 4.5 3.2 4.2 48.0 73.7 2.4 6.9 25.0 6.2 1.3 5.9 6.6 4.3 0.0 16.5 1.8 4.2 15.5 15.3 2.9 17.6 4.4 36.4 4.3 2.0 2.5 1.2 10.3 17.3 17.6 2.2 4.9 7.7 7.7 10.1 2.5 3.9 1.6 16.5 0.0 28.6 5.7 16.2 32.4 15.7 4.6 5.0 29.8 16.0 8.4 29.5 9.4 6.2 12.1 7.7 4.2 4.7 3.0 144.1 11.1 2.4 128.0 9.1 5.3 0.0 4.5 4.6 37.6 18.1 2.3 2.4 7.7 11.1 2.2 3.5 5.9 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 63 "epididymis: 98.8" "Cell type enhanced" "Detected in some" "Adipocytes: 1.5;Alveolar cells type 2: 1.3;Breast myoepithelial cells: 2.2;dendritic cells: 1.1;Endothelial cells: 2.2;granulocytes: 1.3;Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.08e-4)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (3.22e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-3)" "unprognostic (2.93e-2)" "unprognostic (9.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (4.20e-1)" 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 98.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.0 0.1 0.1 1.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.7 0.6 2.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.4 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 256.8" "Group enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 561.4;Oligodendrocytes: 2119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 547.0;LHCN-M2: 169.8;TIME: 203.3;U-2 OS: 163.2;U-87 MG: 112.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020415 Approved "Secreted to blood" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020415: AB_2670434" "unprognostic (9.93e-3)" "unprognostic (2.38e-1)" "unprognostic (2.71e-2)" "unprognostic (8.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (9.19e-2)" "unprognostic (6.64e-3)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.28e-3)" 13.9 21.7 55.3 13.6 126.6 0.2 6.2 93.9 105.1 17.5 7.6 37.0 17.0 26.8 44.9 17.0 10.9 34.0 20.6 68.1 90.1 10.7 0.7 20.9 0.8 118.1 89.3 10.1 3.4 4.2 2.9 4.6 121.0 13.5 38.4 40.2 3.9 22.1 0.8 9.7 26.2 25.8 99.1 3.2 19.7 2.3 82.3 0.3 4.0 0.7 3.6 15.7 9.5 256.8 0.1 1.5 1.4 0.0 3.7 0.2 0.1 4.8 0.0 12.6 16.9 0.0 21.2 0.0 0.1 0.1 8.8 19.6 0.0 0.8 9.3 0.1 9.2 0.0 54.5 0.0 99.9 1.0 0.2 25.6 2.6 61.0 8.5 547.0 21.7 0.0 0.0 0.3 169.8 0.1 0.1 0.3 8.7 0.0 39.4 0.1 41.4 0.1 28.2 0.0 4.5 0.5 0.0 0.3 0.1 26.1 0.2 0.2 203.3 60.8 163.2 2.1 56.6 1.6 0.0 0.1 112.6 0.1 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 126.6 93.9 105.1 68.1 90.1 118.1 89.3 121.0 99.1 82.3 256.8 3.1 9.6 6.0 14.0 0.1 12.1 1.7 13.7 14.8 179.2 0.3 11.7 13.3 0.0 4.5 3.7 2.1 0.3 0.1 5.9 0.0 0.1 32.8 0.4 7.2 10.4 22.9 0.0 219.9 0.0 0.0 34.8 0.0 0.3 5.7 1.3 1.4 0.1 0.3 5.0 216.5 9.2 2.0 0.0 3.3 19.8 2.5 0.3 3.6 32.8 0.0 5.4 0.0 561.4 2119.7 0.4 8.1 3.8 0.0 0.9 0.0 0.9 1.2 11.6 6.6 0.2 40.2 1.9 1.5 9.3 16.1 0.4 0.6 16.2 8.4 0.7 EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6;fallopian tube: 19.7" "Group enriched" "Detected in some" 4 "Early spermatids: 29.6;Endometrial ciliated cells: 31.9;Late spermatids: 20.1;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPTEC TERT1: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: AB_10672605, HPA057532: " "unprognostic (2.06e-3)" "unprognostic (1.87e-2)" "unprognostic (2.96e-2)" "unprognostic (4.34e-3)" "unprognostic (1.81e-1)" "unprognostic (7.59e-4)" "unprognostic (2.37e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (1.20e-1)" "unprognostic (5.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (4.59e-2)" 0.3 0.4 0.8 0.1 1.0 0.8 0.3 1.7 1.1 1.1 12.6 0.1 0.0 0.3 0.8 0.0 19.7 0.2 0.3 1.4 1.5 0.8 1.2 1.7 0.1 4.9 7.0 1.0 0.6 1.7 3.6 0.1 3.2 3.0 0.0 1.6 0.2 0.2 0.0 0.1 0.3 0.0 3.6 0.4 0.7 6.9 2.4 0.2 1.2 0.0 0.2 0.0 0.1 1.0 0.1 0.7 0.2 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 1.5 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.4 0.6 0.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.7 1.1 1.4 1.5 4.9 7.0 3.2 3.6 2.4 1.0 0.2 3.2 1.7 0.3 0.5 0.5 0.1 0.8 0.0 0.4 0.7 0.4 1.3 1.5 1.8 0.0 2.1 0.0 0.3 0.1 0.0 0.2 29.6 31.9 0.7 0.5 0.0 0.0 2.7 0.2 0.1 0.5 3.1 1.9 0.0 0.1 0.0 1.1 0.1 5.0 0.8 0.3 2.0 0.0 0.0 20.1 0.3 0.3 0.0 0.0 0.1 1.2 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.0 0.9 46.0 5.6 0.0 0.5 0.6 6.8 2.7 0.7 0.3 0.0 0.3 0.3 0.0 0.2 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 372.4;NK-cells: 416.1;Pancreatic endocrine cells: 481.2;Urothelial cells: 431.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 370.3" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" 37.7 78.9 52.5 77.7 56.8 174.3 27.5 31.6 76.9 32.8 20.4 74.3 83.3 33.7 5.9 58.7 29.3 32.9 28.5 75.4 34.9 23.0 33.3 60.0 46.3 100.2 31.4 26.9 75.7 10.7 28.6 21.4 101.7 44.6 29.6 2.7 27.3 19.0 6.4 35.9 96.4 17.3 29.6 140.0 92.0 95.2 36.1 25.2 41.6 4.9 29.5 62.6 40.5 62.9 370.3 91.8 8.8 23.8 14.1 30.0 46.8 46.0 43.4 42.7 40.5 35.5 98.8 79.6 141.6 32.1 54.8 88.1 24.5 80.9 27.0 99.8 47.8 19.1 21.6 57.4 22.5 98.1 160.1 23.9 27.2 87.0 21.9 19.9 55.5 35.5 46.4 37.6 26.6 36.8 50.8 188.6 11.6 50.1 112.9 67.2 82.1 63.4 25.3 76.2 20.1 15.6 40.5 34.3 76.8 6.9 15.1 104.8 105.4 62.5 66.9 196.7 74.8 25.4 63.8 34.9 87.4 193.2 86.8 16.3 33.8 52.5 44.0 34.4 12.7 3.9 9.8 20.9 29.5 4.2 4.6 18.0 133.2 28.5 30.0 10.3 7.6 17.0 52.5 56.8 31.6 76.9 75.4 34.9 100.2 31.4 101.7 29.6 36.1 62.9 54.2 3.2 12.2 5.9 44.1 66.2 123.7 25.2 26.7 1.8 21.3 23.0 7.2 32.9 24.4 22.0 10.4 23.7 372.4 280.0 19.6 69.6 93.6 55.4 28.8 52.6 61.7 28.0 33.9 259.4 222.8 31.1 157.0 69.4 44.5 49.4 23.6 20.9 219.3 0.0 21.9 160.8 24.4 217.1 188.2 221.2 9.9 246.9 23.2 13.1 171.3 4.9 416.1 0.5 3.7 481.2 190.5 6.8 62.9 112.2 305.8 28.1 25.7 5.0 46.0 26.7 28.5 5.4 5.7 48.9 68.5 53.4 120.1 178.3 117.8 431.4 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Astrocytes: 291.2;Excitatory neurons: 798.5;Inhibitory neurons: 373.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 35.2;RPTEC TERT1: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 4.1 1.1 4.5 2.0 6.5 0.1 4.0 1.3 13.6 10.1 0.0 2.3 0.8 1.1 2.0 7.1 2.9 2.7 6.8 3.1 10.2 3.4 0.3 2.4 0.8 0.9 0.3 4.0 0.5 2.5 2.7 2.4 0.6 4.3 2.3 2.5 5.6 4.7 0.5 9.7 0.8 2.2 0.0 5.3 2.5 1.4 2.1 1.4 1.0 1.4 2.5 3.5 4.8 5.4 12.7 22.2 35.2 0.0 16.7 14.2 3.6 0.3 6.3 4.5 11.6 0.2 13.9 0.0 20.5 2.4 7.1 13.1 19.4 18.0 3.6 0.0 12.9 0.1 11.9 0.0 3.1 0.6 0.0 16.0 15.4 0.0 14.4 3.9 13.8 0.0 0.0 0.0 8.3 12.0 0.0 0.0 4.6 0.1 1.9 0.0 16.9 0.4 50.9 15.5 5.8 14.7 6.0 8.9 3.8 11.2 3.9 2.2 0.2 28.3 5.0 17.4 7.1 1.2 0.0 8.3 12.4 0.8 31.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 4.5 6.5 1.3 13.6 3.1 10.2 0.9 0.3 0.6 0.0 2.1 5.4 1.1 9.6 24.4 291.2 0.0 15.9 22.5 18.5 6.2 4.3 11.8 8.5 30.6 11.5 26.0 14.7 0.0 20.3 3.3 4.3 23.5 1.7 1.8 3.2 14.8 8.2 12.0 0.0 798.5 1.3 3.3 16.9 5.6 6.3 0.0 0.1 9.7 0.0 1.7 6.7 373.1 8.5 18.3 0.3 7.0 3.7 18.3 0.4 8.8 37.5 3.6 4.7 2.1 26.2 8.7 13.9 4.9 21.8 1.7 14.1 0.0 0.1 19.6 1.4 0.0 1.3 3.7 0.1 4.0 14.9 24.2 3.8 2.2 2.3 5.9 23.1 EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.6;Early spermatids: 9.2;Excitatory neurons: 9.1" "Cancer enhanced" "Detected in many" "glioma: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.9;AN3-CA: 32.3;hTERT-RPE1: 32.6;SH-SY5Y: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 11000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA001623: AB_1848026" "unprognostic (5.17e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (3.27e-1)" "unprognostic (1.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.21e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.00e-1)" "unprognostic (8.56e-2)" "unprognostic (2.20e-2)" 3.5 2.0 23.1 0.7 25.8 0.0 3.5 0.1 25.3 7.4 5.6 0.7 0.3 10.3 0.5 2.0 5.5 1.2 1.1 23.0 37.3 1.2 1.7 1.0 0.3 9.2 10.7 4.7 1.2 12.0 5.7 1.2 8.7 2.1 0.6 3.6 1.4 0.5 0.3 5.9 0.9 3.7 5.8 0.1 0.8 3.6 38.2 0.4 0.7 0.1 0.9 1.0 2.4 10.7 0.0 1.0 53.9 32.3 1.0 0.7 0.4 0.6 7.2 4.8 3.1 2.0 3.4 0.0 1.1 2.1 0.3 0.4 13.9 6.9 2.8 0.0 6.8 0.2 0.0 0.1 1.5 0.0 0.0 3.1 1.4 1.5 1.1 32.6 0.3 0.5 0.0 0.0 0.9 5.4 0.0 0.0 4.8 0.0 1.0 0.2 0.1 0.0 7.4 0.7 3.4 28.1 0.0 0.0 1.1 9.4 2.9 0.0 0.1 3.2 10.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 25.8 0.1 25.3 23.0 37.3 9.2 10.7 8.7 5.8 38.2 10.7 2.1 0.0 0.0 1.0 0.2 4.1 3.8 4.6 6.8 2.2 5.9 11.6 1.7 1.5 0.9 0.0 0.0 0.3 0.0 0.1 0.0 1.1 9.2 2.5 5.9 1.3 6.7 2.7 9.1 0.2 1.0 4.6 0.0 0.7 1.3 3.3 2.2 0.0 0.4 5.0 6.8 0.3 4.1 0.0 0.4 5.6 4.7 0.2 0.0 1.0 0.0 1.4 0.0 0.5 1.3 0.2 0.0 3.4 0.0 1.6 0.0 0.0 6.0 0.7 0.0 0.0 2.2 0.7 0.7 1.8 2.8 0.3 0.1 1.2 0.0 1.6 EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 110.2;pancreas: 89.5;skeletal muscle: 29.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.9;Breast myoepithelial cells: 8.1;Cardiomyocytes: 8.2;Distal tubular cells: 7.9;Excitatory neurons: 8.5;Inhibitory neurons: 11.2;Muller glia cells: 26.2;Skeletal myocytes: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;SK-BR-3: 11.6;U-251 MG: 3.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 209000 680000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.83e-2)" "unprognostic (1.02e-2)" "unprognostic (8.50e-3)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.64e-3)" "unprognostic (5.06e-4)" "unprognostic (8.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.25e-2)" "unprognostic (1.80e-2)" "unprognostic (2.95e-1)" "unprognostic (7.72e-3)" "unprognostic (4.64e-5)" "unprognostic (2.63e-1)" "unprognostic (9.80e-5)" "unprognostic (3.92e-3)" 0.0 0.0 1.0 0.1 1.0 0.2 14.7 0.2 0.8 0.0 0.2 0.8 0.0 0.4 2.4 0.7 0.3 1.0 2.8 0.9 2.0 110.2 0.0 0.5 0.0 1.4 0.9 0.0 89.5 0.2 0.4 0.0 1.5 1.4 1.1 13.6 15.7 0.4 29.6 0.7 0.2 0.5 1.2 0.1 0.0 0.1 0.7 0.0 3.0 17.4 0.0 0.4 0.1 1.8 0.2 0.2 1.9 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.4 0.1 0.0 0.0 6.4 0.6 1.6 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.6 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.6 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.1 0.5 0.4 0.2 0.0 0.0 0.0 11.6 0.4 1.2 2.8 0.0 0.0 0.9 1.3 0.0 3.6 0.0 0.0 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.0 1.0 0.2 0.8 0.9 2.0 1.4 0.9 1.5 1.2 0.7 1.8 0.1 0.0 0.0 3.3 0.0 1.0 0.2 0.1 0.0 1.0 12.9 8.1 8.2 0.0 0.5 0.0 0.0 0.0 0.2 2.0 7.9 0.2 5.6 0.2 0.1 0.6 0.0 0.0 8.5 5.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 11.2 0.1 0.0 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 26.2 0.0 1.5 0.3 1.0 0.4 0.0 0.0 1.1 0.1 1.2 1.0 1.2 0.0 8.2 0.2 0.5 0.4 0.0 1.4 0.0 0.1 0.1 1.6 0.3 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Early spermatids: 50.7;Late spermatids: 49.1;Leydig cells: 155.4;Sertoli cells: 85.5;Smooth muscle cells: 70.9" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HBEC3-KT: 12.6;hTERT-HME1: 16.4;HUVEC TERT2: 16.1;LHCN-M2: 37.0;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" 41.7 19.8 2.0 2.8 2.5 0.2 47.1 1.9 2.3 15.6 3.5 6.1 1.9 5.6 6.8 4.0 8.2 4.9 26.2 1.5 2.4 6.9 4.7 2.9 14.2 3.2 4.2 23.7 3.1 4.0 5.8 51.6 3.6 14.2 3.2 66.7 6.9 20.6 72.0 5.9 4.7 6.7 1.6 9.8 3.4 15.0 3.6 20.4 9.0 121.2 9.1 7.7 13.0 2.5 3.2 0.0 6.5 0.2 0.8 0.2 0.0 2.9 0.0 0.5 0.1 0.0 0.0 0.1 10.2 0.1 0.1 0.0 0.0 12.6 0.0 0.0 1.6 0.0 6.1 0.0 2.8 0.0 0.1 5.4 0.0 0.1 16.4 0.0 16.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.9 0.0 3.7 0.1 1.3 0.0 0.2 0.0 0.1 15.6 0.6 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.9 2.3 1.5 2.4 3.2 4.2 3.6 1.6 3.6 2.5 11.4 0.0 0.0 0.3 0.0 2.7 0.3 0.0 0.0 1.3 2.4 9.8 2.6 0.0 0.0 0.0 120.9 0.3 0.4 0.0 3.9 0.5 50.7 0.2 3.2 5.4 0.0 0.0 0.6 1.0 0.5 17.8 0.0 0.3 0.0 1.6 1.4 0.0 0.7 0.0 0.9 0.0 0.0 0.0 4.2 49.1 155.4 0.6 5.4 1.9 0.0 3.4 0.0 1.0 0.1 1.3 0.0 30.9 0.0 0.2 0.0 6.5 0.0 33.1 85.5 22.0 70.9 9.8 3.3 0.3 2.0 0.5 0.4 23.5 0.0 0.3 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 161.9;Leydig cells: 99.1;Peritubular cells: 107.2;Sertoli cells: 236.7;Smooth muscle cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 312.2;BJ: 238.5;fHDF/TERT166: 258.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" 195.0 59.9 18.4 32.8 17.6 0.4 133.9 16.5 21.2 110.3 11.9 116.1 14.3 119.9 13.2 53.5 75.4 31.2 85.9 15.9 17.1 24.4 14.4 102.8 9.1 23.3 19.3 68.3 28.2 6.2 12.6 50.3 20.0 62.2 14.7 3.0 34.2 51.1 39.6 54.7 54.5 79.6 17.2 40.3 56.3 11.2 24.1 5.1 49.5 28.2 8.3 112.3 88.8 15.8 62.7 142.7 0.1 1.7 312.2 236.0 0.2 238.5 114.0 86.0 70.0 9.3 31.2 0.0 0.3 258.6 20.3 78.1 1.5 126.5 51.9 0.1 0.8 8.4 78.4 0.7 197.0 0.0 16.6 230.1 109.5 72.5 70.6 113.7 168.4 0.7 26.6 0.2 91.7 11.4 13.3 0.7 1.8 9.2 25.9 1.4 10.0 0.2 69.5 2.9 0.1 0.8 212.5 8.2 6.2 19.1 20.2 4.3 192.6 128.0 27.8 112.5 52.2 0.2 0.2 0.2 119.3 3.3 27.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 18.4 17.6 16.5 21.2 15.9 17.1 23.3 19.3 20.0 17.2 24.1 15.8 161.9 60.9 20.6 10.7 0.3 20.3 29.4 31.0 12.5 5.5 7.3 10.8 11.6 10.0 22.5 5.5 0.0 1.1 0.8 0.1 0.0 21.2 0.6 3.4 60.5 75.4 0.0 8.6 4.0 14.1 1.6 55.8 5.1 4.5 2.5 24.7 48.9 3.1 1.9 0.0 0.9 0.0 2.0 1.3 8.8 4.3 99.1 1.6 8.8 7.5 0.6 1.8 0.0 3.5 0.3 31.1 0.0 107.2 0.1 28.8 0.0 0.1 5.5 0.8 236.7 24.8 139.4 0.9 3.0 15.8 13.5 1.5 1.5 27.2 0.0 33.4 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 287.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 400.8;Basal respiratory cells: 271.6;Club cells: 323.3;Endometrial ciliated cells: 229.6;Glandular and luminal cells: 281.8;Squamous epithelial cells: 251.1;Urothelial cells: 397.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 138.4;HaCaT: 95.7;HBEC3-KT: 107.6;OE19: 132.9;RT4: 214.8;T-47d: 213.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus" "HPA050923: AB_2681275, HPA060734: AB_2684351" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.38e-1)" "unprognostic (6.79e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (7.08e-2)" 0.9 1.1 0.9 14.7 1.7 0.2 199.5 0.9 0.6 120.8 1.3 99.3 42.2 13.9 95.0 200.7 129.6 32.2 0.3 1.1 0.8 25.7 1.3 23.4 1.5 2.6 4.0 0.2 41.1 18.5 0.7 0.1 2.8 82.7 126.3 0.8 287.7 153.4 0.2 53.6 34.1 3.5 2.5 1.2 59.5 0.7 1.3 1.3 2.5 0.0 67.3 50.7 79.2 4.7 46.5 26.8 0.0 0.3 0.0 0.0 0.8 0.0 3.9 0.0 0.2 0.4 138.4 0.1 17.1 0.0 0.2 95.7 0.0 107.6 0.5 0.1 0.2 0.0 1.5 0.2 0.0 0.2 0.0 0.0 41.7 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.8 0.2 132.9 1.0 0.0 0.1 1.0 20.2 214.8 0.0 0.2 0.5 14.8 0.2 0.0 213.5 0.5 0.0 0.2 1.2 5.1 0.4 0.5 0.2 0.3 0.3 0.2 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.7 0.9 0.6 1.1 0.8 2.6 4.0 2.8 2.5 1.3 4.7 0.8 48.1 97.2 1.3 0.6 109.6 400.8 271.6 133.1 0.0 123.0 51.9 0.9 60.1 323.3 55.2 0.0 0.1 1.1 62.7 15.6 77.8 14.2 229.6 17.7 4.0 23.3 0.0 0.7 86.5 0.0 3.2 53.5 281.8 1.3 0.0 0.0 0.4 0.1 0.0 0.0 82.8 116.0 0.0 17.7 1.0 0.0 5.1 12.4 0.0 5.6 3.8 0.0 0.0 2.4 104.8 30.2 0.0 1.2 173.1 14.1 0.3 204.6 0.0 0.0 0.0 9.6 0.4 0.1 251.1 170.1 1.4 4.9 0.0 74.5 397.3 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017183 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 237.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1599.6;Gastric mucus-secreting cells: 1390.9;Paneth cells: 1506.1;Proximal enterocytes: 1476.3;Urothelial cells: 1628.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 209.6;CAPAN-2: 296.0;OE19: 196.3;RT4: 215.3;SK-BR-3: 405.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA003316: AB_1078757, HPA003479: AB_1078756" "unprognostic (9.90e-3)" "unprognostic (1.72e-1)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (5.05e-3)" "unprognostic (7.67e-3)" "unprognostic (7.07e-2)" "unprognostic (9.92e-3)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-3)" 1.6 0.2 0.2 12.7 0.1 0.8 79.2 0.8 0.4 55.3 0.1 161.3 142.9 12.9 4.5 237.0 35.5 77.6 5.0 0.1 0.2 66.7 79.2 59.8 0.3 0.0 0.0 1.2 120.7 8.4 3.9 6.1 0.1 58.7 127.5 1.0 147.1 14.8 0.2 14.5 145.6 7.3 0.0 0.5 122.7 0.2 0.1 1.6 6.6 0.0 16.0 165.2 93.6 0.2 56.1 209.6 0.0 0.4 0.0 0.0 63.5 0.0 7.9 0.0 0.1 47.3 296.0 0.3 24.0 0.0 1.7 53.8 0.0 0.2 0.0 6.7 0.2 0.0 38.3 9.2 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.7 0.3 0.7 3.3 196.3 17.6 0.1 0.1 3.0 78.3 215.3 0.3 0.4 2.4 405.7 0.2 9.2 28.8 0.0 0.1 0.0 0.7 0.4 0.5 1.2 3.9 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.4 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 2.7 294.9 422.9 0.0 12.2 5.1 691.3 879.7 113.8 1.5 470.3 180.3 1.5 586.2 1130.0 329.2 18.8 76.6 9.5 1599.6 41.1 792.7 0.0 812.3 90.8 16.4 452.2 2.7 0.4 641.0 122.2 15.9 1390.9 1127.5 40.6 0.2 0.4 38.6 9.3 0.0 0.2 1225.3 1102.7 2.5 2.7 0.0 0.0 18.6 8.8 0.0 15.4 2.6 1.0 0.5 0.1 512.5 1506.1 0.0 6.0 1014.2 1476.3 147.1 888.2 67.3 0.0 0.8 46.3 0.0 0.3 418.5 8.4 257.2 18.7 0.3 983.0 1628.9 ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.2;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 45.5;Excitatory neurons: 11.6;Inhibitory neurons: 16.2;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 18.2;basal ganglia: 13.8;cerebral cortex: 17.5;hippocampal formation: 16.6;white matter: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 12.0;CAPAN-2: 11.2;GAMG: 12.3;RPMI-8226: 11.7;RPTEC TERT1: 21.5;U-2 OS: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000781: AB_1079280" "unprognostic (2.74e-1)" "unprognostic (6.81e-2)" "unprognostic (2.80e-2)" "unprognostic (1.31e-5)" "unprognostic (3.28e-1)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "unprognostic (4.25e-2)" "unprognostic (6.05e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (4.51e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" 0.0 0.6 18.2 0.0 13.8 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 16.6 0.9 0.2 0.2 0.6 0.0 2.7 2.7 0.0 0.2 0.0 0.0 0.0 1.9 0.6 0.0 6.1 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.1 1.7 2.2 2.2 0.0 0.0 0.0 0.0 0.0 4.8 12.0 4.9 0.0 0.0 0.0 0.9 0.0 5.3 2.8 1.2 0.1 1.9 11.2 0.2 6.8 3.8 12.3 8.2 0.6 1.1 0.1 0.2 0.1 0.0 5.7 0.0 0.2 0.0 0.1 0.9 0.1 0.4 1.6 4.5 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.0 0.3 7.1 10.6 0.1 0.1 11.7 21.5 0.1 1.0 0.0 4.9 6.2 0.0 0.1 0.0 0.1 0.5 0.0 24.1 0.2 3.5 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 13.8 0.0 17.5 16.6 0.9 2.7 2.7 1.9 2.8 2.2 4.8 0.1 0.0 5.1 1.3 0.5 0.1 0.0 0.9 0.0 45.5 0.0 0.0 0.0 1.5 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.2 0.0 0.0 11.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.3 16.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 1.9 0.0 0.9 0.0 36.7 0.9 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.6 2.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044305 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 52.5;placenta: 35.3;retina: 27.9" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Cone photoreceptor cells: 29.2;Extravillous trophoblasts: 19.7;Sertoli cells: 19.7;Spermatocytes: 23.0" "Group enriched" "Detected in many" 8 "breast cancer: 11.9;glioma: 25.8;liver cancer: 24.0;melanoma: 14.2;prostate cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 31.2;HBF TERT88: 29.0;Hep G2: 23.4;RH-30: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "prognostic favorable (6.73e-5)" "unprognostic (4.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-5)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.89e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (6.92e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-12)" "unprognostic (9.98e-4)" "unprognostic (8.86e-2)" "unprognostic (3.41e-1)" "unprognostic (9.47e-2)" 1.2 0.9 8.6 1.5 10.7 0.0 4.8 10.0 13.9 0.2 4.0 0.5 0.2 0.5 2.3 0.4 0.2 0.6 3.2 9.0 8.8 0.2 52.5 0.2 0.5 10.6 9.3 0.2 2.6 9.7 2.9 35.3 9.8 5.3 0.1 27.9 0.7 0.4 1.0 0.2 0.3 0.7 9.6 0.0 0.1 11.5 8.8 1.1 1.8 0.9 0.9 2.0 0.1 14.1 0.0 5.3 20.1 0.0 0.0 0.0 11.5 0.4 1.0 17.7 29.9 0.0 0.0 0.0 0.0 1.1 31.2 0.0 21.3 0.0 29.0 0.0 18.2 0.1 0.4 23.4 0.9 0.4 4.8 0.2 0.0 13.7 0.0 1.0 0.0 0.9 1.2 0.0 0.4 0.1 12.1 0.2 3.8 0.0 17.4 16.6 31.8 0.0 0.0 0.3 8.0 9.1 0.0 0.0 7.5 16.1 3.7 9.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 10.7 10.0 13.9 9.0 8.8 10.6 9.3 9.8 9.6 8.8 14.1 0.5 0.0 0.0 95.0 0.1 0.1 0.0 0.0 0.0 2.2 7.8 1.3 1.2 8.6 0.0 0.0 29.2 2.3 0.0 0.0 0.0 7.2 10.1 0.0 0.5 1.9 0.0 0.0 2.5 1.0 19.7 8.0 0.0 0.0 0.0 0.3 0.0 17.5 1.2 0.0 5.9 0.0 0.0 0.0 0.0 14.9 0.9 0.1 0.0 6.5 0.0 4.9 0.0 4.5 16.8 1.0 0.0 0.4 0.0 1.9 0.0 0.1 0.0 11.8 19.7 0.1 3.9 23.0 8.9 0.2 0.0 1.6 0.1 0.0 0.0 0.1 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EML1 "ELP79, EMAP, EMAPL, HuEMAP" ENSG00000066629 "EMAP like 1" O00423 14 99737693-99942060 "Disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Lissencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.4;Excitatory neurons: 57.5;Late spermatids: 61.3;Microglial cells: 69.3;Oligodendrocytes: 61.8;Rod photoreceptor cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.3;HDLM-2: 89.5;U-2197: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033137, HPA049105" Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB033137: AB_2098052, HPA049105: AB_2680633" "unprognostic (9.86e-3)" "unprognostic (2.54e-1)" "unprognostic (8.18e-2)" "unprognostic (2.77e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (2.68e-2)" "unprognostic (8.09e-3)" "unprognostic (7.83e-2)" "unprognostic (3.06e-3)" "unprognostic (1.89e-2)" "unprognostic (9.98e-2)" "unprognostic (4.09e-3)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.81e-3)" "unprognostic (7.03e-3)" 15.5 6.4 8.6 9.1 25.5 0.3 9.7 7.3 12.7 13.2 15.0 35.5 6.8 16.1 10.8 24.1 15.1 18.6 17.2 8.6 7.9 8.6 5.5 13.2 3.3 9.2 9.0 3.8 8.7 28.3 9.2 27.2 10.7 9.6 14.9 50.1 5.0 16.9 47.5 9.4 10.1 31.0 9.4 3.9 14.9 8.0 8.9 1.3 14.8 34.4 4.4 17.1 10.3 22.8 0.0 44.9 36.8 12.9 20.1 39.5 0.3 35.9 67.3 25.2 8.4 5.1 0.9 0.0 22.2 22.6 30.3 0.2 26.7 3.1 11.5 89.5 13.6 0.0 7.9 0.8 4.8 0.1 0.9 11.6 4.9 31.0 11.7 16.0 44.5 0.7 0.1 0.0 10.4 21.3 0.1 0.1 14.5 0.1 17.2 5.4 13.5 0.2 56.2 0.6 14.1 20.9 11.8 1.8 0.0 24.1 13.7 1.2 42.3 22.8 4.1 104.3 14.9 0.5 0.0 0.3 57.3 0.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 25.5 7.3 12.7 8.6 7.9 9.2 9.0 10.7 9.4 8.9 22.8 22.8 16.0 7.0 17.3 0.3 2.8 1.2 0.4 1.2 9.2 1.0 1.3 15.0 1.5 4.5 3.7 158.4 2.7 0.1 0.1 0.0 4.6 29.1 15.9 14.2 30.1 0.0 0.0 57.5 4.9 0.6 20.6 4.1 4.7 0.0 1.6 40.0 1.3 1.3 1.7 29.9 0.6 0.0 2.5 4.7 61.3 7.2 1.9 7.2 69.3 0.6 8.8 1.0 17.6 61.8 0.8 0.0 6.0 1.2 1.4 0.0 2.5 11.8 113.6 0.0 20.8 8.7 4.8 11.3 0.4 4.0 2.9 0.7 1.2 0.0 0.7 EML5 "EMAP-2, FAP16, HuEMAP-2" ENSG00000165521 "EMAP like 5" Q05BV3 14 88612431-88792752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7;ovary: 17.4;retina: 9.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Excitatory neurons: 79.5;Granulosa cells: 98.7;Inhibitory neurons: 106.8;Oligodendrocyte precursor cells: 98.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 17.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 11.5;SH-SY5Y: 23.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 41.5" "HPA054019, HPA055379" Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "HPA054019: AB_2682345, HPA055379: AB_2682799" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (2.49e-1)" "unprognostic (8.68e-2)" "unprognostic (1.15e-1)" "unprognostic (4.67e-4)" "unprognostic (3.42e-2)" "unprognostic (4.50e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.36e-1)" "unprognostic (1.11e-4)" "unprognostic (1.21e-2)" "unprognostic (1.05e-1)" "unprognostic (3.82e-1)" "unprognostic (1.53e-3)" 0.4 3.8 3.3 0.7 2.8 0.3 0.8 17.7 2.8 0.7 0.0 1.3 0.2 0.4 0.2 0.8 1.1 0.1 0.2 3.4 2.4 1.4 1.6 0.6 0.2 0.5 5.5 17.4 0.9 2.4 3.9 0.0 1.5 4.4 0.3 9.5 0.8 0.2 0.1 0.5 0.8 0.2 0.3 0.9 0.6 2.7 2.7 0.7 1.6 0.1 0.6 0.8 0.5 1.1 1.3 0.5 0.0 1.0 0.0 0.0 2.6 0.4 0.3 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.2 3.5 4.1 0.1 0.1 2.2 2.2 1.1 0.5 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.5 11.5 0.1 1.2 2.9 0.0 0.2 0.4 1.0 1.4 0.0 0.4 0.1 3.1 3.9 23.8 1.1 1.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 1.7 4.7 1.0 3.7 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.8 17.7 2.8 3.4 2.4 0.5 5.5 1.5 0.3 2.7 1.1 0.2 0.0 5.8 31.3 3.5 0.5 1.0 0.0 0.6 28.2 2.0 0.9 1.5 1.5 1.3 0.0 60.5 0.2 0.7 1.2 0.0 0.9 3.1 2.0 1.2 0.8 10.7 2.1 79.5 0.4 0.1 1.2 3.1 1.9 1.3 98.7 0.0 0.1 0.0 20.2 106.8 0.3 0.0 0.0 0.0 2.9 0.6 0.3 3.6 17.8 0.2 3.6 0.0 98.0 34.5 0.3 1.1 1.2 4.5 5.7 0.0 0.4 4.6 30.1 0.0 1.9 7.4 13.6 8.1 1.5 0.4 0.1 1.7 5.1 0.1 0.6 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 163.6;kidney: 90.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 663.2;Proximal tubular cells: 177.6;Sertoli cells: 157.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HEK 293: 7.5;MOLT-4: 1.8;SuSa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 11.6 2.2 0.4 1.5 0.5 0.1 4.8 0.4 2.5 1.6 1.8 1.2 36.6 12.9 4.1 1.7 2.3 4.4 4.3 0.6 0.5 90.0 29.0 4.6 0.8 0.9 0.8 1.2 1.3 45.2 1.2 15.5 0.7 1.8 0.8 0.0 1.1 1.2 2.3 0.7 163.6 10.6 0.5 9.2 1.2 0.5 0.4 4.4 5.0 8.9 0.3 2.6 1.6 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.8 0.3 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 1.3 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.5 0.6 0.5 0.9 0.8 0.7 0.5 0.4 0.8 10.7 0.0 2.0 1.6 1.1 1.7 0.1 0.0 0.0 0.0 0.2 0.1 3.9 0.0 0.3 11.0 0.0 37.0 0.0 1.5 17.6 0.0 0.5 3.1 40.7 2.2 1.8 0.0 7.3 0.0 3.5 15.4 0.0 2.3 0.0 0.0 1.4 31.4 2.7 0.0 2.9 28.4 2.0 1.0 1.9 0.2 0.6 1.1 0.0 1.0 0.0 0.0 1.0 0.0 0.8 0.0 31.6 0.4 0.1 0.2 663.2 177.6 1.7 0.0 157.8 0.8 54.1 0.0 0.2 0.1 1.0 58.6 1.9 0.5 42.1 0.1 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Gastric mucus-secreting cells: 13.3;Proximal enterocytes: 13.2;Squamous epithelial cells: 28.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "CACO-2: 17.9;HaCaT: 16.6;HBEC3-KT: 13.5;MCF7: 15.0;NTERA-2: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.1 0.0 0.0 1.3 0.0 0.3 2.2 0.4 0.1 11.2 1.2 3.7 8.4 0.3 1.2 57.2 3.4 1.5 0.0 0.0 0.0 5.8 15.6 2.3 2.0 0.0 0.0 0.0 5.7 206.5 2.5 0.6 0.0 4.0 1.6 0.0 11.0 1.2 0.0 19.7 6.2 0.1 0.0 0.9 4.2 1.9 0.0 3.4 5.4 0.0 3.5 1.9 25.8 0.1 8.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 17.9 7.1 0.0 0.1 0.0 0.0 16.6 0.0 13.5 0.0 0.0 0.0 1.8 0.0 1.7 0.0 0.8 0.1 0.0 4.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 15.0 0.0 1.9 54.4 8.8 0.0 0.0 0.0 0.0 1.1 6.7 0.3 0.0 0.0 8.2 0.0 3.2 3.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.2 0.0 3.8 2.9 0.1 0.1 0.0 0.4 0.1 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.2 0.3 0.1 2.0 6.3 6.5 6.8 0.0 3.3 5.0 1.0 2.8 9.9 7.3 0.0 2.0 0.2 4.2 0.0 4.4 23.3 4.0 1.0 0.2 1.2 0.0 0.6 4.3 2.6 0.5 13.3 6.6 0.0 0.0 0.4 8.8 0.4 0.0 0.3 4.7 2.0 0.3 0.3 9.9 0.6 0.3 0.0 1.0 0.0 0.3 0.0 0.5 0.2 6.3 8.8 0.0 0.6 2.0 13.2 1.5 2.1 0.2 0.0 0.4 0.4 0.5 1.9 28.7 3.7 1.0 4.4 0.0 7.6 5.5 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Metabolic proteins, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 21.3" "Group enriched" "Detected in some" 10 "Excitatory neurons: 202.5;Inhibitory neurons: 162.8;Oligodendrocyte precursor cells: 96.0" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.5" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 10.0;PC-3: 9.4;TIME: 12.6;U-138 MG: 25.5;U-2197: 15.7;U-251 MG: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 33000 "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.0 0.8 3.3 0.1 5.3 0.0 0.0 0.0 21.3 2.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.8 16.2 2.4 0.0 0.0 0.1 0.0 2.6 1.4 2.3 0.0 0.0 0.7 0.9 4.0 1.5 0.1 1.5 0.3 1.4 0.0 0.2 0.0 0.2 1.8 0.3 0.3 0.7 0.3 0.0 0.9 0.0 0.0 0.1 0.5 3.1 0.0 0.7 0.8 0.0 0.8 0.4 0.0 0.4 1.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 4.4 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 0.3 0.0 0.0 1.5 2.6 0.0 0.0 0.0 0.1 0.0 9.4 0.0 2.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 12.6 25.5 3.1 15.7 20.6 0.0 0.0 0.0 2.6 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.3 0.0 21.3 16.2 2.4 2.6 1.4 4.0 1.8 0.3 3.1 0.0 0.0 0.0 8.5 0.0 0.5 0.0 0.0 0.0 2.7 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 2.2 0.1 0.0 0.0 202.5 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.7 162.8 0.0 0.0 0.0 0.0 15.2 0.9 0.0 3.6 5.6 0.0 5.7 0.0 96.0 4.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.7 0.4 0.0 0.1 0.0 0.0 0.7 0.0 0.1 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.9;skin 1: 76.5;vagina: 36.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Club cells: 19.3;Squamous epithelial cells: 30.7;Suprabasal keratinocytes: 43.3;Urothelial cells: 23.3" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Cell line enhanced" "Detected in some" "EFO-21: 2.5;NTERA-2: 2.3;OE19: 8.4;SuSa: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.5 0.3 0.8 0.2 0.8 0.2 1.5 0.6 0.9 14.7 0.7 0.2 0.2 0.4 0.3 68.9 1.7 1.3 0.5 0.7 0.9 3.3 0.3 1.7 0.1 0.9 0.8 0.7 0.2 3.0 1.8 0.4 0.8 1.5 0.2 0.2 7.6 0.9 0.4 76.5 0.3 0.4 0.8 2.6 0.8 2.1 0.9 1.7 0.4 0.1 26.7 8.6 36.6 0.8 0.1 0.2 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 2.5 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.3 2.3 8.4 0.3 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.2 0.8 0.8 0.6 0.9 0.7 0.9 0.9 0.8 0.8 0.8 0.9 0.8 0.2 0.0 1.1 0.0 0.2 7.0 2.6 15.5 0.0 0.4 0.9 0.6 0.5 5.7 19.3 5.5 0.0 1.6 0.0 0.1 1.9 0.5 0.2 0.7 0.4 0.6 0.0 0.0 0.1 0.0 3.4 0.6 0.0 1.7 0.0 0.4 1.1 0.0 0.6 0.0 0.1 0.1 2.0 3.2 1.4 0.0 0.0 1.5 0.0 0.0 0.6 2.5 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.6 0.2 0.0 3.3 0.0 0.0 0.8 2.5 4.6 2.1 30.7 43.3 2.6 0.2 0.2 0.1 23.3 EPM2A "LD, LDE" ENSG00000112425 "EPM2A glucan phosphatase, laforin" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Glycogen storage disease, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.8;tongue: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Early spermatids: 33.0;Excitatory neurons: 30.4;Inhibitory neurons: 50.7;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 23.2" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.8 6.0 11.4 1.5 11.7 1.8 3.2 11.9 17.8 3.1 7.3 17.2 3.2 6.0 4.3 9.3 4.4 3.6 24.4 11.6 12.6 8.5 5.7 3.0 3.3 11.9 11.5 5.7 2.4 5.2 3.8 1.5 11.1 6.1 2.9 12.1 3.1 8.8 76.8 2.1 3.8 6.3 10.3 2.1 5.3 3.0 11.5 4.8 3.9 79.5 2.6 9.8 2.7 13.3 1.3 2.1 3.4 6.6 8.6 2.3 1.6 3.1 3.8 2.9 3.5 1.7 1.7 23.2 2.7 3.8 3.5 1.8 1.3 1.6 2.6 9.3 1.9 3.6 2.5 2.7 4.8 12.7 2.4 2.0 7.0 1.7 0.7 3.8 2.0 5.0 1.8 5.4 3.8 3.1 8.4 3.2 3.9 3.2 1.9 4.8 3.1 6.7 2.5 1.8 6.3 6.4 5.5 3.3 7.8 3.1 1.9 7.3 4.6 2.9 1.1 2.7 2.6 4.1 4.6 8.6 2.6 2.8 4.8 0.0 0.0 0.0 0.1 0.5 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.9 0.1 1.9 0.1 0.3 0.0 0.3 11.4 11.7 11.9 17.8 11.6 12.6 11.9 11.5 11.1 10.3 11.5 13.3 3.9 6.4 1.5 66.9 4.4 0.9 1.0 0.8 0.6 8.4 3.5 2.2 27.8 2.8 2.2 1.8 6.2 1.0 1.9 0.2 11.7 1.0 33.0 1.9 3.6 2.2 1.2 4.4 30.4 2.3 0.7 2.3 1.1 1.4 2.5 6.0 1.4 6.6 2.3 30.3 50.7 1.5 2.0 3.3 1.4 19.8 3.1 3.1 7.2 15.9 1.7 7.9 2.1 56.8 60.1 1.2 1.7 2.2 1.7 1.5 0.5 7.1 2.2 6.3 0.0 6.2 2.4 4.9 1.6 0.8 0.4 0.4 1.8 5.1 1.2 0.3 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 254.4;Gastric mucus-secreting cells: 80.5;Intestinal goblet cells: 103.4;Late spermatids: 144.6;Paneth cells: 257.8;Proximal enterocytes: 285.3;Undifferentiated cells: 112.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 15.6;CAPAN-2: 14.4;Hep G2: 36.2;OE19: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" 0.0 0.0 0.1 10.8 0.0 0.0 0.2 0.0 0.0 1.3 0.0 77.1 141.8 0.2 0.9 0.1 0.1 35.7 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 77.1 0.0 0.0 0.2 0.0 0.0 142.1 2.9 0.0 0.0 50.7 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.6 14.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 67.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 14.3 0.3 0.0 0.0 0.0 0.0 254.4 0.0 11.6 28.0 0.7 0.1 0.3 51.4 0.0 0.0 23.9 0.0 0.0 80.5 1.0 4.5 0.0 0.0 0.2 0.0 0.0 0.0 103.4 0.0 0.0 0.0 144.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 257.8 0.4 0.3 0.0 285.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.4 0.6 112.6 1.8 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 247.8;Intestinal goblet cells: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" 67.3 147.8 33.4 49.1 31.2 44.9 60.3 47.4 35.4 127.2 26.7 97.7 79.5 67.4 75.3 55.0 72.4 50.2 60.9 35.8 31.8 66.1 193.2 77.8 40.8 41.4 36.4 56.9 80.6 50.7 48.5 47.9 38.1 146.8 102.7 21.6 97.6 69.8 92.3 46.7 79.4 64.1 33.0 69.2 107.1 25.3 41.3 83.1 75.2 91.9 55.0 58.3 54.3 34.0 120.2 112.8 95.0 211.6 353.3 262.0 51.9 239.5 179.3 105.5 97.4 159.5 120.4 114.8 166.9 406.4 181.7 43.2 68.5 316.8 123.3 92.0 67.5 70.7 156.1 86.1 258.9 33.3 21.6 223.8 128.6 155.8 143.8 173.8 171.0 117.8 42.6 156.8 177.1 150.4 96.5 57.6 56.0 283.7 101.4 327.4 62.9 358.5 245.2 68.6 52.9 96.0 82.7 234.7 120.6 91.1 98.0 37.4 132.4 171.3 69.1 165.9 99.2 246.8 294.0 47.5 236.9 78.3 76.2 3.7 7.5 19.2 3.1 10.5 5.2 9.3 1.6 2.1 6.1 6.2 1.0 2.3 30.6 14.3 14.3 3.1 1.0 5.1 33.4 31.2 47.4 35.4 35.8 31.8 41.4 36.4 38.1 33.0 41.3 34.0 41.9 57.7 29.5 22.9 62.0 22.8 32.1 22.7 14.8 37.2 51.2 35.1 32.9 68.6 29.4 49.7 16.7 20.7 44.3 83.6 21.5 101.9 11.5 36.2 48.0 33.5 26.0 25.9 35.4 60.8 90.3 47.2 49.5 77.9 23.5 64.4 37.5 247.8 41.1 21.9 41.8 202.9 36.7 77.0 105.2 33.8 65.0 54.8 7.2 30.0 91.1 39.0 36.0 47.7 30.6 86.9 59.3 58.3 96.2 74.2 95.0 38.5 28.4 12.6 39.5 56.1 41.1 1.9 10.5 27.2 26.9 9.0 25.1 103.5 73.3 47.8 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925646 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "placenta: 152.2" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 130.7;Extravillous trophoblasts: 258.3;Syncytiotrophoblasts: 88.8" "Cancer enriched" "Detected in some" 18 "testis cancer: 74.5" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 7 "BEWO: 296.4" "Secreted in female reproductive system" NA NA 57000 "Cluster 1: Neutrophils - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (5.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (7.74e-2)" "unprognostic (3.12e-3)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" 0.1 0.4 0.5 0.2 0.8 0.7 0.1 2.3 1.3 0.0 0.7 0.1 0.3 0.2 0.2 0.1 0.1 0.3 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.6 0.0 0.2 0.7 0.0 152.2 0.7 0.7 0.0 1.5 0.4 0.0 0.4 0.8 0.5 0.0 0.0 0.4 0.3 1.4 0.4 1.3 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.7 0.1 0.0 0.0 296.4 0.1 0.0 0.0 0.0 11.9 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 2.8 1.4 0.4 0.1 1.2 0.2 0.0 0.0 0.2 0.0 0.1 11.1 1.0 0.7 0.6 0.0 0.2 8.2 5.0 0.9 0.0 0.3 6.4 0.3 0.1 0.0 0.2 0.4 0.3 0.1 0.0 0.0 44.6 0.3 0.2 0.3 0.2 0.6 0.4 0.1 0.9 2.9 0.5 0.4 3.0 0.2 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 7.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 2.3 1.3 0.6 0.0 0.6 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 130.7 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 258.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 19.2 3.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 88.8 0.0 0.0 0.0 0.0 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 38: Heart - Muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favorable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" 10.8 16.5 11.3 7.2 12.0 3.8 6.3 7.6 13.7 8.9 5.8 11.1 5.5 13.8 5.4 12.3 11.3 7.9 31.1 14.7 10.4 7.0 6.2 8.6 5.4 10.7 14.3 10.0 11.9 18.9 10.3 13.8 7.2 8.5 5.4 11.2 8.1 11.8 20.8 11.1 6.7 17.9 8.9 8.6 9.0 10.3 23.4 6.4 7.7 22.7 4.8 10.6 7.2 12.7 45.3 33.6 70.1 37.0 18.8 18.5 15.6 33.7 32.6 20.3 16.4 28.9 15.9 12.2 46.6 40.1 28.2 29.7 34.5 55.1 22.4 8.9 18.9 17.2 15.7 14.3 9.8 8.6 46.9 22.2 36.7 15.9 14.6 16.9 44.3 17.4 16.2 15.4 16.5 8.5 15.5 4.7 49.2 13.3 13.6 18.4 31.3 7.1 31.2 29.0 15.2 26.6 14.3 8.6 17.3 22.0 8.4 9.4 34.9 26.6 62.7 25.4 28.9 7.9 17.9 13.5 22.5 10.3 23.7 3.0 1.3 2.0 1.7 0.9 0.8 0.3 0.7 0.9 1.3 0.4 0.5 0.4 5.7 0.5 1.4 1.1 0.3 0.8 11.3 12.0 7.6 13.7 14.7 10.4 10.7 14.3 7.2 8.9 23.4 12.7 6.3 3.2 4.4 10.4 2.4 5.0 2.9 8.7 6.8 17.5 4.8 4.2 26.8 7.2 5.0 1.8 25.0 3.7 7.1 4.9 3.9 9.7 32.0 4.2 7.0 7.3 4.2 1.3 20.0 10.6 16.9 6.5 4.1 5.9 5.7 3.0 8.2 9.0 4.4 8.4 19.0 2.4 2.0 6.6 2.5 10.1 9.9 6.1 5.4 16.9 5.7 6.7 23.7 13.0 16.6 12.3 2.4 14.3 4.2 6.3 2.1 3.5 4.9 16.2 26.3 8.4 9.6 4.3 9.1 4.3 3.0 2.2 4.5 8.6 3.1 3.1 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 128.5;Proximal enterocytes: 87.4;Spermatocytes: 89.0" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 37.5;OE19: 18.8;RT4: 42.4;SK-BR-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 7.5 14.2 23.5 2.9 28.4 10.4 9.5 25.6 29.6 7.5 29.3 18.9 22.0 3.9 9.1 8.7 12.0 5.2 5.0 24.6 23.3 20.0 32.8 7.8 2.5 32.1 25.4 3.9 22.4 24.6 19.0 3.4 28.7 44.1 15.2 5.5 17.4 7.1 9.5 12.1 22.0 2.3 27.9 3.3 17.1 46.8 26.4 7.1 38.6 5.6 2.7 6.9 8.2 45.8 5.0 1.2 0.8 1.0 1.2 0.8 37.5 1.0 0.5 0.5 0.8 7.3 11.4 0.3 3.9 0.7 0.4 16.2 0.7 2.3 0.2 2.2 5.4 0.1 0.2 3.5 0.8 1.4 2.8 0.6 10.7 0.4 1.3 0.4 0.0 0.9 0.1 0.8 0.0 10.7 0.8 2.2 3.2 18.8 0.4 0.9 0.4 0.2 9.0 42.4 4.8 3.6 5.6 21.2 0.2 0.9 14.6 14.5 0.0 0.1 0.6 1.1 0.7 2.1 1.0 0.6 0.1 13.4 0.4 0.0 6.9 29.1 0.4 1.9 0.2 0.1 0.4 0.2 8.2 0.1 0.6 0.6 0.4 0.5 1.0 8.8 0.2 1.4 23.5 28.4 25.6 29.6 24.6 23.3 32.1 25.4 28.7 27.9 26.4 45.8 1.2 22.4 13.2 6.5 2.4 5.2 29.0 6.8 10.2 15.5 15.4 9.0 2.9 27.1 11.0 22.0 43.8 16.3 7.3 51.6 0.0 12.4 50.7 9.5 1.9 1.8 15.5 6.6 15.7 6.4 8.7 3.7 37.8 6.0 0.0 6.3 0.4 37.1 2.8 1.7 11.4 38.2 10.2 2.5 4.2 128.5 7.5 3.3 5.4 1.9 2.5 7.3 0.0 7.5 45.1 4.2 41.3 4.5 0.7 20.1 87.4 22.6 5.2 14.5 0.0 2.9 3.2 89.0 23.0 6.4 6.0 12.4 1.2 1.3 55.2 18.9 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM135A "FLJ20176, KIAA1411" ENSG00000082269 "Family with sequence similarity 135 member A" Q9P2D6 6 70412941-70561174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.1;Horizontal cells: 238.9;Inhibitory neurons: 172.8;Microglial cells: 132.1;Oligodendrocyte precursor cells: 219.2;Oligodendrocytes: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031743, HPA031744" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA031743: AB_10600767, HPA031744: AB_10601101" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "prognostic favorable (8.00e-4)" "unprognostic (1.59e-1)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (6.69e-4)" "unprognostic (4.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "prognostic favorable (3.46e-4)" "unprognostic (3.99e-1)" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "unprognostic (2.65e-2)" 2.6 2.8 2.5 4.8 3.6 1.3 2.5 8.1 3.3 4.9 0.6 10.7 13.6 6.3 2.5 29.8 4.1 7.0 4.1 3.2 2.1 4.9 2.4 4.2 3.8 2.4 2.3 6.3 6.0 9.7 1.9 4.0 2.4 16.1 11.1 8.2 4.5 3.5 2.6 9.6 11.5 3.7 1.2 3.5 10.7 10.1 2.2 2.9 3.8 6.5 6.4 4.9 7.1 3.7 7.9 4.8 9.5 6.1 4.5 3.2 8.9 2.5 5.0 2.6 4.3 8.9 6.2 14.3 18.1 1.9 12.6 7.3 9.6 5.6 4.6 6.8 8.2 6.2 4.6 8.0 5.5 12.3 6.4 2.9 13.8 5.0 13.4 3.1 7.2 4.4 10.6 6.8 3.1 0.8 2.2 5.5 6.4 9.2 3.9 6.8 31.3 6.8 9.8 4.0 10.1 3.1 2.9 2.6 3.0 6.3 1.8 5.2 3.6 2.2 5.7 2.2 5.8 8.5 10.3 5.5 1.6 10.4 4.2 1.8 2.3 0.1 0.8 2.0 0.9 1.6 0.7 0.3 3.5 2.0 1.1 0.7 0.6 2.7 3.3 0.5 0.9 0.9 2.5 3.6 8.1 3.3 3.2 2.1 2.4 2.3 2.4 1.2 2.2 3.7 12.0 28.9 12.5 85.8 10.8 15.9 12.9 8.3 31.3 20.8 4.5 4.1 11.5 17.2 8.9 20.2 29.2 2.9 4.7 49.9 5.9 6.7 30.4 13.9 15.6 13.0 23.4 1.7 170.1 12.4 1.5 10.2 45.9 21.4 8.8 13.5 9.7 6.5 5.6 238.9 172.8 29.2 16.2 10.6 15.5 23.8 15.5 11.9 5.4 132.1 11.9 13.8 4.1 219.2 121.3 18.4 31.7 13.2 6.4 35.4 24.0 10.0 9.9 26.4 6.6 11.6 9.3 33.2 10.5 71.4 33.5 8.2 4.6 10.9 25.5 15.8 FAM155B "CXorf63, TED, TMEM28" ENSG00000130054 "Family with sequence similarity 155 member B" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 7.4;HAP1: 16.2;Hep G2: 6.1;NTERA-2: 24.3;OE19: 6.5;SCLC-21H: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036093: AB_10673613" "prognostic unfavorable (4.61e-5)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "unprognostic (3.09e-4)" "unprognostic (7.07e-2)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (1.83e-4)" "prognostic favorable (6.63e-4)" "unprognostic (1.46e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-1)" "unprognostic (8.21e-2)" 0.1 0.8 2.2 0.0 2.1 0.0 0.2 3.0 2.6 0.2 0.5 0.3 0.1 0.3 0.4 0.1 0.7 0.2 43.5 2.1 2.7 0.9 0.2 0.1 0.1 2.4 3.1 0.1 1.8 3.1 2.4 0.0 3.4 0.9 0.2 0.4 1.1 4.9 0.1 0.0 0.2 0.1 2.0 0.7 1.1 1.5 3.5 0.1 8.0 0.0 0.1 0.2 0.1 2.3 0.0 2.7 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.7 0.0 5.2 0.0 0.0 0.0 16.2 0.6 0.0 0.0 5.0 0.0 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.2 0.0 0.0 24.3 6.5 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.8 0.1 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 3.0 2.6 2.1 2.7 2.4 3.1 3.4 2.0 3.5 2.3 0.2 0.0 0.0 1.3 0.0 0.0 0.3 1.6 0.0 0.4 0.6 0.1 23.7 0.0 0.8 1.8 0.0 0.0 0.0 0.5 0.0 0.5 0.0 2.0 0.5 0.7 1.2 0.0 0.8 1.2 0.0 0.4 0.0 4.4 0.0 0.0 0.4 0.3 0.1 0.0 0.9 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.8 0.2 0.0 0.0 1.2 0.0 0.5 0.3 0.8 0.0 0.1 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM168B "KIAA0280L, MANI" ENSG00000152102 "Family with sequence similarity 168 member B" A1KXE4 2 131047876-131093460 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043778, HPA061659" Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043778: AB_10964889, HPA061659: AB_2684577" "unprognostic (8.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.26e-2)" "unprognostic (4.58e-2)" "unprognostic (6.90e-3)" "unprognostic (1.60e-2)" "unprognostic (2.10e-1)" "unprognostic (5.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.84e-2)" "unprognostic (1.88e-1)" "prognostic favorable (5.30e-5)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (3.35e-3)" 41.5 33.7 55.5 26.8 67.7 46.2 32.1 49.8 60.1 35.4 32.6 54.2 26.3 51.4 26.5 34.4 37.9 23.7 43.4 57.5 52.1 38.4 30.9 27.6 27.8 51.4 53.6 46.9 30.1 46.7 20.3 29.4 54.0 37.5 31.9 48.6 28.1 46.8 69.9 29.9 34.3 40.8 54.7 24.2 36.3 26.8 60.1 38.5 36.2 52.9 31.3 47.6 28.0 55.8 74.1 47.6 98.2 67.7 82.2 62.4 74.0 75.2 54.9 46.3 39.7 88.1 40.0 78.6 61.1 79.8 31.8 57.1 83.8 83.8 66.2 64.8 62.3 72.1 49.8 67.4 83.0 84.8 58.6 63.6 82.4 94.5 81.0 62.3 65.5 72.3 70.3 28.9 72.2 53.4 68.0 55.3 61.6 60.2 57.5 85.0 82.5 70.2 63.7 84.0 71.3 100.0 58.2 58.8 80.1 46.0 52.4 79.2 70.8 77.3 78.9 58.0 73.9 67.9 81.2 98.1 65.9 49.3 70.7 2.5 2.2 4.3 4.4 1.5 4.0 3.0 3.6 3.7 2.0 3.0 4.7 3.4 2.1 2.5 3.4 3.3 3.2 2.8 55.5 67.7 49.8 60.1 57.5 52.1 51.4 53.6 54.0 54.7 60.1 55.8 24.4 35.3 27.4 25.1 19.0 22.8 18.3 24.5 16.5 32.2 28.6 23.6 51.4 24.3 21.6 35.0 37.5 27.0 22.5 38.8 5.9 24.8 12.3 28.0 21.6 22.8 31.8 13.3 47.9 30.8 24.8 23.8 19.4 29.0 19.0 34.7 22.1 39.8 20.1 30.3 52.2 29.8 14.2 25.1 16.0 11.1 29.2 19.2 24.9 28.1 20.9 27.0 14.4 18.6 38.8 38.0 25.3 49.7 25.1 33.3 27.3 26.8 19.5 42.3 13.1 27.5 27.4 18.2 22.8 20.0 25.1 38.3 19.0 23.2 36.7 31.0 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Intestinal goblet cells: 60.9;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cell line enhanced" "Detected in many" "CACO-2: 74.3;MCF7: 91.8;OE19: 76.3;RPMI-8226: 109.6;RT4: 221.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Intermediate filaments" "HPA015306: AB_2669182" "unprognostic (3.00e-3)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "prognostic favorable (9.03e-5)" "unprognostic (4.68e-2)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (8.23e-3)" "unprognostic (7.67e-3)" "unprognostic (5.05e-3)" "unprognostic (6.60e-2)" "unprognostic (1.33e-1)" "unprognostic (4.67e-2)" "unprognostic (2.01e-1)" "unprognostic (6.64e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-2)" 5.6 5.6 13.8 5.9 13.2 1.1 27.2 9.7 14.6 16.9 9.1 10.7 6.3 8.2 7.2 8.4 24.0 6.1 10.5 13.9 14.5 5.3 6.9 21.0 8.5 14.0 16.0 16.2 76.6 2.9 26.5 6.7 14.6 32.2 15.2 6.4 52.5 16.2 16.2 8.4 8.5 4.9 7.8 4.0 35.0 17.9 14.9 8.0 37.2 15.9 7.4 26.3 6.6 19.5 0.3 12.2 8.0 2.4 0.0 0.2 1.0 4.6 21.8 0.2 0.0 74.3 8.6 1.2 20.6 0.6 5.8 0.4 13.9 0.5 0.0 0.5 6.5 0.7 1.4 1.0 1.3 1.1 3.2 1.0 0.3 0.2 0.2 0.5 10.5 6.8 1.2 54.7 12.2 91.8 2.7 0.1 39.2 76.3 0.0 8.9 22.5 109.6 5.4 221.3 4.9 3.9 6.4 42.7 14.3 22.7 33.8 7.9 0.0 0.0 1.6 0.3 10.3 1.7 17.2 2.6 0.2 0.8 5.3 0.9 0.6 0.8 0.1 0.7 0.2 0.3 1.8 0.0 0.5 0.3 2.0 2.6 2.9 0.7 0.0 3.5 8.9 0.6 13.8 13.2 9.7 14.6 13.9 14.5 14.0 16.0 14.6 7.8 14.9 19.5 8.5 105.8 22.2 13.7 1.7 2.3 14.7 1.7 5.7 7.0 26.3 11.3 5.2 5.7 12.6 7.3 8.4 1.4 2.3 3.7 7.9 5.5 22.6 17.8 4.2 10.3 42.1 0.8 24.0 14.6 21.2 4.9 19.4 23.4 18.4 1.3 22.1 7.0 5.4 11.8 24.4 60.9 24.4 3.8 4.8 57.8 5.9 4.9 12.4 22.5 0.4 3.9 0.0 17.1 44.8 19.1 1.6 1.9 6.6 24.2 3.0 1.5 14.5 3.7 0.0 7.7 3.7 1.0 5.0 3.9 3.0 0.7 3.4 1.8 5.5 24.3 FAM178B LOC51252 ENSG00000168754 "Family with sequence similarity 178 member B" Q8IXR5 2 96875882-96986580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 18.9;brain: 10.5;epididymis: 5.5;lymphoid tissue: 12.1;testis: 8.2" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 88.3" "Cancer enriched" "Detected in many" 5 "melanoma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 25.7;OE19: 7.0;RPMI-8226: 28.0;WM-115: 27.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 2.4" "HPA042516, HPA062110" Uncertain Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "Nuclear speckles" "Golgi apparatus" "HPA042516: AB_10806241, HPA062110: " "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" "unprognostic (8.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.28e-2)" "unprognostic (9.02e-4)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (6.49e-3)" "unprognostic (1.49e-1)" "unprognostic (5.13e-2)" "unprognostic (9.82e-11)" "unprognostic (6.93e-2)" "unprognostic (1.57e-1)" "unprognostic (9.63e-3)" "unprognostic (1.08e-1)" 1.7 0.0 4.9 0.0 8.7 18.9 0.9 6.3 7.3 0.5 2.3 2.2 0.0 1.6 5.5 0.7 1.3 0.1 0.4 4.7 6.8 0.1 0.0 0.4 0.1 7.7 8.0 0.5 0.0 0.0 0.1 0.9 7.4 1.1 0.1 0.1 0.3 0.8 0.2 1.2 0.5 0.4 6.5 12.1 0.3 8.2 7.3 0.1 0.1 0.0 0.0 2.1 0.8 10.5 6.2 0.0 0.0 2.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.5 2.5 0.0 0.0 0.2 7.0 0.0 0.0 6.7 28.0 0.0 0.0 0.8 0.0 0.0 4.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 27.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.1 4.9 8.7 6.3 7.3 4.7 6.8 7.7 8.0 7.4 6.5 7.3 10.5 0.2 0.0 0.0 1.0 1.2 0.8 0.6 0.4 0.0 0.2 0.5 1.4 0.4 0.0 0.0 0.0 2.1 3.2 0.5 0.1 0.0 0.0 3.6 0.1 0.3 0.2 0.0 88.3 7.2 0.0 7.1 3.0 0.0 0.1 0.0 0.2 0.4 0.0 1.2 1.7 1.1 0.0 10.2 0.0 0.9 7.8 0.9 1.0 3.6 1.0 0.2 2.9 1.0 1.0 20.7 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 2.8 1.6 3.2 20.1 0.6 1.7 2.5 0.2 0.3 0.1 0.4 FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 12 "Early spermatids: 266.3;Late spermatids: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" 0.1 0.1 0.2 0.4 0.3 2.9 0.4 1.2 0.4 0.2 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.7 0.5 0.6 0.5 0.0 0.3 0.2 0.0 0.1 0.3 0.3 0.4 9.8 0.3 0.2 0.1 0.0 0.5 0.2 0.0 0.6 0.0 0.2 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.9 0.0 0.0 2.9 0.1 0.0 0.2 0.3 1.2 0.4 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.6 0.0 0.0 3.1 0.3 0.4 0.0 0.4 1.0 0.0 4.1 0.8 0.4 0.4 0.0 1.8 0.0 0.0 0.1 16.1 0.3 0.0 0.1 266.3 0.5 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.4 1.2 2.0 0.3 0.0 122.0 2.1 0.4 0.0 0.0 0.2 1.9 0.0 1.0 0.7 0.2 1.6 0.7 0.3 1.3 0.0 0.1 2.7 5.5 0.0 0.1 0.2 6.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 1.3 FAM237B ENSG00000283267 "Family with sequence similarity 237 member B" A0A1B0GVD1 7 90316503-90321308 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 1.6;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hypothalamus: 1.6;thalamus: 4.9" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 264.8;intestine: 488.7;salivary gland: 468.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 794.8;Intestinal goblet cells: 1150.1;Paneth cells: 776.7;Proximal enterocytes: 353.1;Undifferentiated cells: 760.0" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Cell line enriched" "Detected in some" 65 "OE19: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" 0.9 0.1 0.2 29.6 0.1 0.0 18.5 0.0 0.5 31.3 0.1 362.0 89.2 0.6 0.2 264.8 0.8 81.6 0.2 0.2 0.1 1.1 0.2 4.8 0.6 0.1 0.2 0.1 1.7 0.0 0.4 1.0 0.1 14.8 488.7 0.0 468.4 68.4 0.1 2.6 90.4 8.3 0.1 0.2 78.2 0.3 0.3 0.4 1.5 0.0 41.1 12.7 59.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.1 0.4 0.2 68.5 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 0.0 0.3 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.2 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.6 0.0 1.1 0.3 3.4 0.0 9.9 223.1 0.0 0.0 29.5 53.8 0.2 47.1 133.4 14.7 0.0 0.0 1.3 794.8 0.0 1.3 0.5 0.0 0.0 2.5 152.1 0.0 0.1 0.0 0.0 0.8 114.2 0.2 8.9 0.0 0.4 0.2 0.3 0.0 0.1 1150.1 18.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 776.7 0.0 0.2 68.2 353.1 1.2 43.1 0.0 0.0 0.0 4.9 0.1 0.6 7.9 0.1 0.4 2.0 0.0 760.0 245.0 FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 111.3;vagina: 55.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 71.2;Club cells: 58.2;Pancreatic endocrine cells: 28.7;Squamous epithelial cells: 19.3;Suprabasal keratinocytes: 15.2;Urothelial cells: 25.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 52.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 83.5;HBEC3-KT: 126.3;hTCEpi: 66.4;K-562: 206.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA052615: AB_2797244" "unprognostic (4.48e-2)" "unprognostic (2.03e-3)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.98e-9)" "unprognostic (2.62e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (2.04e-1)" "unprognostic (2.22e-16)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "unprognostic (6.07e-2)" 0.2 0.6 0.0 0.1 0.0 0.2 0.3 0.2 0.1 18.9 0.1 0.1 1.0 0.0 1.3 111.3 4.3 1.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 0.0 0.1 7.5 6.4 0.1 10.2 2.4 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.4 0.0 7.4 3.8 55.8 0.0 83.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.7 10.6 0.0 0.0 25.9 0.0 126.3 0.0 0.0 0.1 0.8 9.2 0.0 0.0 0.1 0.1 0.0 66.4 0.0 16.8 0.0 0.0 0.1 206.3 0.1 0.0 0.3 0.0 0.1 0.0 4.2 0.1 0.0 0.0 0.1 0.0 18.4 0.1 0.0 14.4 9.7 0.1 0.2 1.5 0.2 0.6 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 4.0 71.2 1.2 0.0 4.4 0.9 1.1 0.0 58.2 1.8 0.0 0.1 0.0 1.0 0.0 0.3 1.0 0.0 0.1 0.1 0.0 0.0 0.6 0.7 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 10.2 0.0 0.4 1.6 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 28.7 0.2 0.0 0.1 0.7 1.1 0.1 9.6 0.0 0.0 0.1 1.4 2.2 0.6 19.3 15.2 0.0 0.1 0.0 0.8 25.0 FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.9;Basal squamous epithelial cells: 17.6;Early spermatids: 11.8;Squamous epithelial cells: 26.1;Suprabasal keratinocytes: 64.2" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.2 5.3 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.2 0.0 0.1 42.3 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.1 0.6 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 27.9 1.1 0.0 17.6 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 6.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.3 1.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 26.1 64.2 0.0 0.0 0.0 0.1 1.9 FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.8;Early spermatids: 26.0;Gastric mucus-secreting cells: 74.9;Intestinal goblet cells: 26.9;Paneth cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CAPAN-2: 2.9;OE19: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" 0.1 0.1 0.2 3.7 0.3 0.4 1.4 0.8 0.5 10.6 0.2 32.7 30.0 1.1 0.1 7.0 3.9 6.4 0.2 0.3 0.2 0.8 0.3 8.0 0.2 0.1 0.1 0.0 1.2 0.0 0.2 0.6 0.2 3.2 16.6 0.2 28.5 0.4 2.7 1.9 30.0 1.0 0.0 0.2 37.4 2.2 0.2 0.1 0.1 0.0 1.3 1.2 4.1 0.5 0.4 0.4 0.0 0.7 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 2.9 0.5 0.2 0.1 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.8 1.1 9.4 0.9 0.2 0.1 0.3 0.0 0.2 0.5 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.1 0.1 0.2 0.1 1.0 0.1 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.8 0.5 0.3 0.2 0.1 0.1 0.2 0.0 0.2 0.5 0.0 9.6 13.4 1.3 0.4 0.0 1.4 0.8 0.6 0.0 1.8 0.8 2.1 8.6 6.5 1.8 0.0 0.1 0.3 22.8 0.0 0.1 26.0 4.8 0.5 0.2 5.4 0.0 0.3 1.1 0.1 0.2 74.9 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 26.9 2.0 0.0 0.0 9.3 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 1.6 16.5 0.0 0.4 3.3 12.7 0.0 5.1 0.0 0.0 0.2 0.2 0.8 0.5 2.3 0.0 0.1 0.3 0.1 12.8 6.9 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 8.3 9.0 4.1 9.3 8.3 17.1 9.3 1.2 8.5 4.3 0.0 34.5 17.6 5.6 36.2 7.4 3.6 5.2 6.6 6.2 9.2 5.0 3.8 11.3 7.9 1.2 2.9 2.3 3.2 1.3 2.4 18.1 1.3 2.6 28.2 9.4 4.4 1.9 6.3 9.0 19.2 7.6 1.4 12.2 4.9 9.2 5.2 7.0 4.4 2.6 3.0 6.5 3.7 4.9 2.5 4.9 4.9 1.2 6.8 26.9 2.1 21.3 24.7 5.8 5.4 8.2 28.0 3.7 5.4 3.4 4.3 1.5 13.4 0.2 1.4 1.8 32.2 76.2 10.7 2.7 14.7 30.0 24.0 7.5 0.2 8.7 11.0 14.3 84.0 2.9 6.6 2.7 0.9 0.8 19.9 74.2 19.3 1.6 54.5 16.1 7.9 3.1 25.7 7.2 8.6 7.9 4.8 89.6 37.8 9.7 4.1 28.2 68.2 15.6 4.6 5.6 9.3 4.4 4.9 1.8 24.5 38.5 13.7 3.8 22.8 50.0 5.0 13.9 3.4 2.0 8.3 6.2 8.1 1.8 2.9 3.2 41.0 4.0 8.0 3.1 16.1 9.6 4.1 8.3 1.2 8.5 6.2 9.2 1.2 2.9 1.3 1.4 5.2 4.9 9.1 0.0 3.3 7.8 0.6 1.3 0.1 0.2 0.6 2.0 1.4 0.8 12.1 0.0 1.4 0.0 0.0 16.0 1.1 35.7 0.0 0.1 31.5 0.4 2.9 11.9 7.2 4.6 114.3 0.2 19.6 4.8 5.6 0.4 10.8 0.0 9.7 0.0 19.3 5.0 172.1 21.8 0.0 22.2 3.7 6.4 1.2 12.2 16.0 63.7 6.9 0.5 1.0 24.6 6.9 3.3 36.8 0.4 8.0 0.4 15.1 0.4 3.2 1.2 0.0 4.2 3.6 16.6 1.0 0.3 0.3 193.9 4.2 0.9 23.7 0.3 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.3" "Cell type enhanced" "Detected in some" "Astrocytes: 265.8;Excitatory neurons: 512.9;Inhibitory neurons: 149.2;Oligodendrocyte precursor cells: 88.4" "Cancer enriched" "Detected in single" 6 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.3;fHDF/TERT166: 2.2;NTERA-2: 2.5;SuSa: 2.2;U-2 OS: 2.1;U-251 MG: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 4700 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA026878: AB_1848430, HPA074824: " "unprognostic (5.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.76e-6)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-1)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-4)" "unprognostic (8.83e-2)" "unprognostic (7.72e-2)" "unprognostic (2.25e-1)" 0.5 0.0 5.5 0.0 19.3 0.0 0.1 1.3 9.0 0.6 0.0 0.2 0.0 0.6 0.6 0.1 0.6 0.0 0.2 4.0 15.5 0.2 0.0 1.2 0.0 0.5 4.7 0.5 0.0 0.0 2.9 0.1 1.9 2.0 0.1 1.3 0.0 3.8 0.1 0.2 0.0 0.1 0.8 0.1 2.2 0.7 7.5 0.1 0.0 0.2 0.2 2.3 1.0 1.0 0.0 0.3 7.3 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 1.4 2.2 0.0 1.2 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.2 2.1 0.0 4.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 19.3 1.3 9.0 4.0 15.5 0.5 4.7 1.9 0.8 7.5 1.0 0.0 0.0 0.0 265.8 0.0 0.1 0.3 0.9 0.0 20.8 0.1 0.5 1.8 0.0 0.1 14.7 0.0 0.1 0.0 0.1 0.0 0.7 4.8 0.1 0.2 0.2 0.0 0.0 512.9 0.0 0.1 1.9 0.0 0.0 0.0 3.7 1.4 0.0 0.1 0.0 149.2 0.0 24.4 0.0 0.0 3.8 1.2 0.3 0.0 13.1 0.0 0.8 0.0 88.4 7.0 0.2 0.0 7.5 0.0 0.6 0.0 0.0 0.0 1.7 0.0 2.5 4.4 1.0 6.5 0.1 0.0 0.0 0.0 44.8 0.0 0.1 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Excitatory neurons: 57.1;Inhibitory neurons: 60.1;Oligodendrocyte precursor cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 26.0;HAP1: 23.8;SCLC-21H: 34.2;SH-SY5Y: 23.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039106: AB_10697546" "unprognostic (8.03e-2)" "unprognostic (4.91e-2)" "unprognostic (5.04e-3)" "unprognostic (6.44e-2)" "unprognostic (3.80e-1)" "unprognostic (5.00e-3)" "unprognostic (7.56e-2)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (2.47e-3)" "unprognostic (6.70e-4)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (3.49e-3)" 0.7 2.2 11.0 1.5 12.7 0.0 3.2 9.3 19.0 2.5 2.0 22.7 1.5 6.5 11.0 6.2 3.7 2.4 0.8 14.1 7.6 2.7 0.0 1.7 0.1 7.2 5.6 2.2 2.5 6.5 15.9 0.8 6.3 8.2 2.9 10.4 7.4 10.6 0.5 0.9 3.3 7.8 4.4 0.4 7.1 2.1 8.5 2.2 1.7 0.6 0.1 14.3 2.9 11.4 4.0 3.2 10.3 14.3 0.0 0.0 3.8 5.0 3.2 8.1 7.0 1.9 1.3 0.0 0.6 1.0 26.0 0.1 23.8 4.7 7.0 0.0 11.8 0.1 1.9 0.7 0.6 0.0 0.0 0.5 7.5 0.2 3.8 5.9 0.0 2.0 0.5 0.0 2.7 7.0 0.0 0.0 12.2 0.0 4.8 0.0 1.0 0.0 4.3 0.3 34.2 23.7 4.5 3.2 22.6 4.2 10.0 0.0 1.0 2.5 4.7 0.0 15.5 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 12.7 9.3 19.0 14.1 7.6 7.2 5.6 6.3 4.4 8.5 11.4 0.2 25.6 15.2 5.5 0.5 0.4 4.2 4.2 5.7 14.4 5.3 9.0 1.1 0.0 8.1 1.8 10.4 1.2 0.4 0.2 9.8 2.3 2.6 0.6 1.0 1.7 0.0 0.0 57.1 0.7 0.2 1.4 0.0 0.4 3.8 0.4 1.4 0.1 0.2 3.3 60.1 0.2 4.1 0.6 1.1 5.0 0.0 1.2 1.8 2.8 0.1 3.6 2.1 43.7 4.4 1.0 0.1 1.9 0.1 4.8 0.0 1.0 2.1 13.6 0.0 0.2 1.3 1.3 8.9 1.2 0.3 0.3 1.2 0.2 0.4 1.2 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBXL22 "Fbl22, FLJ39626" ENSG00000197361 "F-box and leucine rich repeat protein 22" Q6P050 15 63597353-63602428 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.4;intestine: 60.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "MCF7: 4.9;SCLC-21H: 5.3;U-937: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047624, HPA054627" Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Cytosol" "HPA047624: AB_2680107, HPA054627: AB_2682548" "unprognostic (2.17e-1)" "unprognostic (3.19e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (3.03e-2)" "unprognostic (1.29e-2)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.82e-2)" "unprognostic (1.34e-1)" "unprognostic (1.07e-3)" "unprognostic (1.90e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" 3.6 0.9 1.9 2.8 1.7 0.3 1.8 2.7 2.0 15.7 0.2 60.1 2.9 60.4 3.6 7.0 21.2 8.8 17.2 1.6 1.3 1.0 0.5 1.1 0.9 0.8 1.1 4.5 0.7 0.6 0.7 0.9 0.9 16.9 4.8 0.6 3.2 29.4 4.9 1.4 7.3 28.9 0.5 0.6 11.1 3.0 1.8 0.4 1.5 1.8 0.2 26.3 10.1 1.0 0.7 1.2 0.2 0.8 0.5 0.5 0.1 0.2 0.0 0.3 0.0 0.8 0.9 0.3 0.7 0.2 0.4 0.8 0.6 0.4 0.0 0.8 0.6 0.3 1.1 2.2 0.1 0.4 0.1 0.2 0.2 0.1 0.5 0.1 0.2 2.2 0.0 1.1 0.0 4.9 0.7 0.7 1.7 0.8 0.4 0.7 0.0 2.4 0.3 0.3 5.3 0.2 0.6 1.0 0.3 0.0 1.9 0.6 0.8 0.3 1.0 0.5 0.2 0.7 1.5 0.8 0.5 3.7 0.8 0.2 0.0 0.0 0.5 0.0 0.5 0.6 0.6 0.6 0.0 0.4 1.0 0.4 0.1 0.7 0.0 1.6 0.0 0.2 1.9 1.7 2.7 2.0 1.6 1.3 0.8 1.1 0.9 0.5 1.8 1.0 1.4 0.0 0.0 1.0 3.4 0.1 1.8 0.4 0.6 10.1 4.7 8.6 7.7 2.8 0.7 7.3 4.2 0.7 2.7 2.3 9.8 1.2 0.9 3.2 5.8 1.3 4.9 2.5 1.5 1.1 1.2 3.4 7.7 5.8 0.0 0.9 3.9 4.0 0.7 0.0 1.8 6.1 0.0 1.6 0.4 0.5 0.3 1.7 0.0 0.0 0.7 10.6 2.1 1.5 0.5 0.8 3.0 11.3 9.1 1.7 1.9 4.0 0.1 3.8 0.0 6.2 8.1 3.8 3.2 4.4 0.9 0.5 4.4 2.7 4.0 0.8 FBXO25 FBX25 ENSG00000147364 "F-box protein 25" Q8TCJ0 8 406428-477967 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.8" "Cell type enhanced" "Detected in all" "Early spermatids: 625.7;Late spermatids: 312.5;Spermatocytes: 640.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 58.7;SK-MEL-30: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "prognostic favorable (5.38e-5)" "unprognostic (2.74e-2)" "unprognostic (5.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-3)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (2.39e-3)" "unprognostic (3.30e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.11e-3)" "unprognostic (2.41e-1)" 14.4 20.4 9.3 7.6 9.4 9.1 13.8 13.4 11.8 9.1 8.3 16.6 15.4 8.4 16.8 10.0 8.6 9.3 15.3 8.8 9.2 15.8 30.0 10.4 12.0 8.8 10.2 8.8 28.6 14.2 12.1 6.8 9.1 24.9 18.7 7.2 16.3 10.5 18.3 12.4 11.1 11.0 8.4 8.1 15.1 97.8 8.6 20.7 18.6 19.7 12.1 11.3 9.0 11.4 13.4 10.6 4.5 8.8 6.9 4.4 18.6 12.6 18.5 11.8 18.1 6.0 12.7 0.3 3.4 19.4 17.8 8.5 8.7 24.5 16.1 10.0 14.5 7.1 6.3 28.3 20.5 11.4 13.7 12.7 37.6 3.6 18.7 17.9 5.0 58.7 8.4 0.1 13.9 12.8 50.8 13.6 2.1 29.0 4.6 2.4 3.4 18.1 15.4 22.5 13.7 14.4 12.7 4.2 61.5 11.2 9.0 8.1 7.5 4.8 4.1 0.8 10.1 9.2 14.4 13.6 13.0 4.7 14.7 1.6 9.1 6.6 9.0 10.8 11.1 16.2 10.7 8.5 9.1 10.9 9.5 9.4 0.7 9.9 9.9 9.0 12.5 6.9 9.3 9.4 13.4 11.8 8.8 9.2 8.8 10.2 9.1 8.4 8.6 11.4 21.3 19.2 28.5 15.3 24.2 34.8 19.6 28.0 19.9 31.8 35.9 21.7 36.6 42.9 20.4 35.0 10.4 20.0 26.8 30.4 72.4 53.3 625.7 20.0 17.8 25.7 43.3 12.6 20.5 102.6 18.9 18.2 16.3 27.4 20.3 15.4 28.2 77.0 25.4 53.8 20.0 58.2 42.7 32.7 24.2 312.5 38.8 17.4 39.2 11.2 36.2 22.1 38.1 8.5 28.3 51.5 41.2 29.3 21.4 39.1 34.9 58.3 13.2 36.3 26.3 17.8 16.2 640.9 142.1 17.4 40.5 16.1 19.5 14.4 47.2 21.8 FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 40: Granulosa cells - Unknown function" Microtubules "HPA012583: AB_2668686" "unprognostic (8.69e-2)" "unprognostic (3.35e-3)" "unprognostic (2.92e-2)" "unprognostic (4.29e-2)" "unprognostic (5.47e-3)" "unprognostic (8.36e-2)" "unprognostic (7.61e-7)" "unprognostic (5.79e-2)" "unprognostic (1.63e-1)" "unprognostic (6.32e-2)" "unprognostic (1.18e-2)" "unprognostic (9.25e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (5.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" 4.5 4.0 3.8 4.2 5.0 7.2 4.0 4.6 3.9 4.1 2.7 9.7 4.1 6.7 3.1 9.6 3.2 5.6 7.2 3.1 6.0 4.1 3.4 3.2 4.3 4.5 5.5 5.9 3.8 4.0 1.6 4.8 4.7 6.0 4.7 5.3 4.4 6.8 11.5 2.6 3.5 8.0 4.2 3.7 3.7 6.5 5.1 2.9 8.0 9.1 4.1 5.7 2.9 5.3 3.7 6.9 9.7 13.2 9.9 8.8 9.9 10.3 9.6 6.9 6.8 8.7 3.3 17.0 7.8 11.8 12.6 5.7 8.4 7.5 10.4 10.0 5.8 10.8 9.1 8.8 17.8 14.1 10.8 14.6 8.3 8.6 11.4 9.0 10.1 4.1 12.6 11.9 13.6 2.9 6.4 7.5 11.2 2.4 5.1 8.2 21.7 5.9 7.2 3.8 4.3 6.9 12.6 6.5 6.1 9.6 3.0 13.8 13.4 7.1 6.0 9.1 10.4 8.8 7.2 6.8 11.4 6.0 7.7 9.3 1.3 1.6 0.4 1.1 0.3 0.6 0.4 0.8 1.6 1.3 0.6 0.6 1.2 0.5 0.9 0.5 0.3 0.6 3.8 5.0 4.6 3.9 3.1 6.0 4.5 5.5 4.7 4.2 5.1 5.3 11.1 3.2 5.9 7.2 5.4 14.3 5.3 4.2 12.5 8.8 10.5 8.3 22.9 10.0 4.7 3.7 4.2 5.8 5.7 4.9 11.7 4.7 10.9 4.1 13.7 13.8 6.0 36.7 5.3 3.2 3.4 15.4 7.1 6.2 12.0 37.1 11.4 9.7 7.5 26.9 6.4 5.0 2.0 11.9 20.8 4.4 11.1 10.2 7.2 7.5 7.5 12.0 0.0 5.0 7.6 5.1 3.2 10.1 11.1 7.1 4.3 8.2 2.8 8.7 0.0 26.5 18.4 19.7 10.5 12.4 17.3 5.6 6.2 7.2 5.0 5.0 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "B-cells: 16.8;dendritic cells: 19.1;Oligodendrocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.4;RPMI-8226: 43.3;U-937: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" 2.2 1.8 24.9 14.7 33.7 20.2 1.5 21.7 32.6 1.0 8.6 2.5 3.2 1.3 1.4 1.1 1.5 4.2 0.8 24.1 25.6 1.4 2.2 3.7 24.3 27.5 28.6 1.7 0.7 1.1 3.9 1.1 29.7 1.0 2.2 3.4 1.3 0.8 0.6 22.2 8.1 1.7 19.9 15.5 3.4 4.4 29.2 17.6 1.0 0.8 17.4 3.0 1.0 59.5 0.9 11.9 7.5 5.2 0.2 0.2 7.5 1.1 0.3 0.3 0.5 1.5 1.4 62.4 17.1 0.5 1.4 2.3 3.7 2.3 0.2 27.6 2.1 4.9 1.4 6.4 0.6 15.7 10.2 0.1 0.3 0.0 0.4 0.4 1.6 30.2 24.9 28.9 0.0 17.4 36.2 27.8 3.6 14.7 28.7 30.2 0.2 43.3 0.2 1.2 1.3 2.5 0.3 5.9 0.9 0.9 6.0 15.4 1.3 0.1 4.1 0.9 0.4 18.2 9.0 33.4 0.9 38.5 0.5 13.2 9.6 10.1 7.0 14.3 6.0 12.4 7.9 6.3 14.5 12.3 7.4 6.1 37.8 6.4 11.5 15.3 7.6 7.4 24.9 33.7 21.7 32.6 24.1 25.6 27.5 28.6 29.7 19.9 29.2 59.5 0.4 0.0 1.5 0.7 16.8 0.0 0.4 0.2 0.6 7.8 2.0 4.3 0.9 2.8 0.4 1.8 0.0 2.9 19.1 2.0 0.0 0.5 1.5 0.8 0.2 2.4 1.2 2.5 15.0 0.0 4.6 2.5 1.5 1.0 9.5 2.9 2.5 0.0 6.8 0.0 13.0 1.7 0.0 8.7 14.3 0.7 2.5 11.0 1.8 6.5 12.3 0.1 13.4 3.0 46.9 2.1 0.5 8.6 4.5 0.3 0.1 0.1 0.7 0.8 0.0 0.2 0.6 0.9 5.5 0.2 0.6 0.8 9.8 12.2 1.8 0.3 FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Cell type enriched" "Detected in some" 18 "Hepatic stellate cells: 1192.6" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" 4.7 24.6 0.4 0.0 0.4 0.1 7.6 0.3 0.5 0.3 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.3 0.6 0.4 6.4 99.7 0.1 0.1 0.3 0.5 0.5 0.5 0.2 3.1 0.0 0.4 3.2 0.0 0.0 3.2 0.4 0.1 0.2 0.1 0.0 0.2 3.1 0.2 0.2 0.4 0.0 2.1 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.1 0.0 2.2 0.0 0.0 9.0 0.4 0.4 0.3 0.5 0.6 0.4 0.3 0.5 0.4 0.2 0.4 0.3 0.1 0.0 0.0 0.7 3.8 0.0 0.1 0.0 0.0 0.0 3.8 0.4 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1192.6 12.6 0.0 0.0 0.1 0.0 0.0 64.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FCRL6 "FcRH6, FLJ16056, IFGP6" ENSG00000181036 "Fc receptor like 6" Q6DN72 1 159800511-159816257 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 12.8" "Cell type enhanced" "Detected in some" "dendritic cells: 60.6;NK-cells: 150.4;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 142.9;memory CD8 T-cell: 134.3;naive CD8 T-cell: 102.8;NK-cell: 51.3" "Group enriched" "Detected in many" 26 "NK-cells: 51.3;T-cells: 142.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.64e-3)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.62e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (5.79e-3)" "unprognostic (6.65e-3)" "unprognostic (2.76e-2)" "unprognostic (3.91e-1)" "unprognostic (1.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.52e-5)" "unprognostic (3.98e-1)" "unprognostic (1.13e-1)" "unprognostic (8.78e-2)" "unprognostic (9.18e-2)" 0.8 1.5 0.3 1.9 0.4 7.9 1.1 0.7 0.4 0.6 0.3 0.7 1.0 1.3 2.3 0.6 1.0 2.2 0.8 0.4 0.5 0.6 3.3 5.7 5.8 0.9 0.5 1.4 0.3 0.3 0.3 0.5 0.6 0.7 0.5 0.0 2.3 0.4 0.5 0.3 1.4 0.9 0.5 12.8 0.8 0.4 0.6 1.3 0.6 0.1 1.9 1.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.1 142.9 0.3 3.0 0.1 25.5 134.3 3.7 0.1 10.9 102.8 1.5 51.3 1.4 0.2 0.1 53.6 0.3 0.4 0.7 0.4 0.4 0.5 0.9 0.5 0.6 0.5 0.6 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 60.6 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.7 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 1.0 1.1 0.0 150.4 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "Fermitin family member 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 230000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: AB_10673300, HPA072965: " "unprognostic (4.38e-2)" "unprognostic (4.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.42e-2)" "unprognostic (2.51e-2)" "unprognostic (4.89e-3)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.58e-1)" "unprognostic (1.99e-1)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (7.69e-2)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" 148.4 21.2 28.7 38.8 31.6 0.5 57.6 29.0 37.3 44.7 18.0 104.3 13.1 105.1 26.3 46.8 55.7 65.7 66.9 31.0 27.4 55.4 108.3 47.9 15.3 35.7 29.1 43.6 20.6 18.4 13.1 116.5 33.5 69.1 33.3 29.5 22.6 117.9 48.8 13.4 29.3 155.6 30.6 37.6 46.4 15.5 27.6 6.9 35.9 69.6 6.6 77.7 29.1 38.1 22.8 18.9 101.6 46.8 163.7 133.7 84.6 148.4 95.2 172.3 107.9 34.1 17.6 0.1 49.4 153.1 33.8 9.6 80.1 11.1 128.3 0.2 22.6 31.9 83.1 40.3 209.6 0.4 12.6 129.4 23.5 95.3 125.4 78.5 91.2 16.8 0.6 153.4 131.7 28.0 7.7 0.5 64.3 0.2 51.3 3.9 103.8 0.4 60.9 20.6 6.2 130.5 157.8 35.0 37.7 103.3 30.1 1.1 115.2 134.5 92.4 108.2 56.0 22.6 29.4 0.6 30.9 0.2 33.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 31.6 29.0 37.3 31.0 27.4 35.7 29.1 33.5 30.6 27.6 38.1 152.7 76.9 42.0 116.5 1.0 18.6 150.6 15.5 13.6 39.5 33.8 41.4 65.8 24.3 25.6 40.5 37.5 74.8 2.3 0.2 31.3 48.5 68.2 20.1 141.7 110.4 0.0 2.7 13.7 33.2 178.1 103.9 3.6 40.2 58.3 31.6 110.3 82.3 10.4 15.2 16.1 0.5 4.1 8.9 19.5 27.9 74.9 4.4 46.2 29.0 4.8 52.3 1.0 41.2 92.0 27.6 0.1 174.9 4.5 40.0 0.0 44.7 10.1 56.0 151.2 83.4 174.1 4.1 16.2 2.2 8.1 102.6 7.9 12.3 0.4 37.0 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FGD3 "FLJ00004, ZFYVE5" ENSG00000127084 "FYVE, RhoGEF and PH domain containing 3" Q5JSP0 9 92947523-93036236 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.4;lymphoid tissue: 32.4" "Cell type enhanced" "Detected in many" "dendritic cells: 41.8;Early spermatids: 66.1;Late spermatids: 99.0;NK-cells: 69.0;T-cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 43.9;Karpas-707: 61.4;RT4: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA020963, HPA021018" Approved Approved Nucleoplasm,Cytosol NA NA 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA020963: AB_2670542, HPA021018: AB_2670564" "unprognostic (5.66e-3)" "prognostic favorable (5.51e-4)" "unprognostic (5.05e-3)" "unprognostic (1.75e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.23e-7)" "unprognostic (2.26e-1)" "unprognostic (1.03e-2)" "unprognostic (2.61e-2)" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.32e-1)" "unprognostic (8.56e-2)" "unprognostic (3.96e-1)" "unprognostic (1.60e-1)" "unprognostic (9.66e-2)" "unprognostic (1.22e-2)" 4.7 1.3 1.8 21.9 1.6 39.4 3.5 1.8 4.9 1.5 2.5 3.0 3.1 1.1 0.4 2.4 2.1 4.6 2.0 1.6 2.7 4.9 2.0 10.2 30.8 3.4 2.6 1.4 7.6 0.4 0.7 3.5 3.5 1.7 2.3 0.0 4.9 1.5 1.1 3.2 11.3 2.7 2.7 29.5 4.3 6.5 3.5 32.4 3.3 2.2 17.6 8.1 3.5 4.0 13.3 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 16.0 9.1 11.3 0.6 0.0 0.1 8.4 0.6 0.0 0.0 19.7 0.1 17.4 0.1 0.6 0.0 4.8 43.9 0.0 0.3 0.0 0.0 0.0 0.0 18.8 0.7 61.4 0.0 22.8 20.7 20.4 0.4 4.3 1.1 20.1 0.0 16.3 0.1 33.5 1.2 0.4 0.0 14.4 0.4 0.4 5.8 21.4 0.0 0.0 0.6 0.1 0.1 6.2 6.6 5.4 3.1 10.3 0.0 142.9 50.6 139.6 49.5 63.4 49.9 28.6 51.4 46.6 37.5 36.9 50.1 44.7 178.2 39.1 99.2 16.8 48.4 74.0 1.8 1.6 1.8 4.9 1.6 2.7 3.4 2.6 3.5 2.7 3.5 4.0 1.7 22.4 9.2 0.0 25.3 0.8 0.6 0.4 0.6 0.1 5.8 1.8 2.5 4.3 2.3 9.2 0.0 2.9 41.8 0.4 0.0 7.2 66.1 1.2 0.2 2.1 1.8 11.8 0.6 0.2 3.2 0.9 0.0 0.6 19.6 3.7 1.8 0.8 15.5 0.0 1.6 0.6 0.0 22.3 6.2 99.0 0.3 20.7 1.8 12.2 20.1 0.4 69.0 5.0 0.5 0.4 0.1 0.4 15.8 0.1 0.0 0.7 0.3 3.9 0.0 0.3 0.8 1.6 2.4 0.5 1.0 4.5 47.3 0.1 0.4 0.5 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 279.5;Excitatory neurons: 549.6;Inhibitory neurons: 321.3;Leydig cells: 219.0;Microglial cells: 432.8;Oligodendrocyte precursor cells: 212.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 60.1;HUVEC TERT2: 38.7;TIME: 55.3;U-138 MG: 58.8;U-2197: 43.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" 9.2 4.5 0.8 4.5 2.1 0.1 2.9 0.0 8.2 11.0 2.3 2.7 0.9 6.1 3.0 3.5 6.4 9.1 3.8 4.7 0.0 1.4 1.2 2.3 3.5 0.0 0.0 29.6 21.7 1.3 1.9 1.2 0.0 5.1 3.1 3.1 1.9 3.3 7.3 6.1 1.7 5.2 0.0 3.0 2.2 4.6 0.2 1.2 4.9 3.1 2.6 5.3 4.2 0.0 0.0 0.2 8.9 0.0 7.9 14.5 0.0 9.7 6.3 9.0 8.4 0.0 0.0 0.0 0.0 28.5 0.9 2.0 13.6 18.6 21.8 0.0 7.8 0.0 5.3 0.0 25.2 2.1 0.0 8.0 10.6 7.5 60.1 2.7 38.7 0.0 0.0 0.0 21.8 0.0 0.0 0.0 4.2 0.0 0.2 0.0 10.8 0.0 0.0 0.0 2.1 0.0 2.3 0.0 3.2 11.8 0.0 0.1 55.3 58.8 9.9 43.0 17.8 0.0 0.0 0.0 18.5 0.0 5.8 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 2.1 0.0 8.2 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.9 0.0 1.3 279.5 0.1 21.4 1.7 5.2 6.2 7.0 3.9 4.4 4.0 10.0 0.4 1.8 0.0 0.4 0.1 0.1 0.0 66.2 3.1 2.2 65.1 15.9 0.0 0.0 549.6 42.8 0.2 34.3 0.5 1.6 0.0 39.9 66.0 0.2 2.4 10.1 321.3 0.0 0.0 1.3 6.6 7.7 219.0 1.2 1.8 432.8 0.6 13.2 0.0 212.1 9.0 20.4 0.0 124.8 0.0 1.1 0.0 0.2 1.7 1.4 13.1 3.2 8.5 1.1 0.6 1.0 24.0 0.8 0.8 32.3 0.0 0.2 FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 156.5;Basal prostatic cells: 168.3;Club cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 27.5;hTCEpi: 51.3;RPTEC TERT1: 17.3;WM-115: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA 1100000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" 5.0 3.7 2.3 0.8 3.0 0.0 2.3 6.4 5.3 3.2 0.9 1.6 11.8 2.3 3.1 1.6 2.4 5.0 0.6 5.3 1.3 23.2 7.0 17.7 0.1 0.0 1.3 10.6 1.2 8.2 1.0 1.8 0.8 8.2 0.8 1.6 1.2 14.0 2.0 6.3 2.3 1.4 0.6 0.7 9.7 1.2 2.3 7.3 5.2 0.7 0.3 7.9 2.1 1.8 0.0 12.2 27.5 0.0 0.0 0.0 0.0 2.7 0.8 0.1 0.0 15.3 5.6 0.0 0.9 0.6 0.0 8.0 0.0 8.3 0.1 0.0 1.8 0.0 0.4 0.3 2.4 0.0 0.0 4.6 51.3 0.0 9.7 0.0 0.1 0.2 0.0 0.2 5.3 0.4 3.7 0.0 8.9 6.2 0.1 0.1 0.2 0.0 17.3 3.6 0.5 5.7 0.0 0.0 9.2 15.5 0.5 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.0 0.0 0.2 0.0 62.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 6.4 5.3 5.3 1.3 0.0 1.3 0.8 0.6 2.3 1.8 0.3 218.0 156.5 2.3 0.5 8.7 168.3 26.1 55.8 23.9 4.4 6.5 1.2 24.3 73.1 22.0 6.2 0.5 0.0 2.2 13.7 23.6 0.2 0.7 1.7 1.9 11.3 0.0 27.2 14.9 0.0 8.7 37.8 0.7 5.1 5.0 2.9 8.5 0.2 6.7 39.3 2.5 2.0 0.3 0.7 0.5 3.7 1.3 5.4 1.9 1.6 0.6 0.0 26.2 3.9 10.0 3.0 0.4 0.1 24.9 3.5 49.2 13.4 3.3 0.0 25.0 1.8 0.0 0.1 5.9 16.6 0.0 0.8 1.4 1.5 18.3 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 277.6;lymphoid tissue: 104.9" "Cell type enhanced" "Detected in many" "B-cells: 108.1;dendritic cells: 160.0;Kupffer cells: 77.4;Langerhans cells: 141.6;Macrophages: 115.5;monocytes: 132.8;NK-cells: 152.4;Plasma cells: 109.8;T-cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 190.8;MOLT-4: 138.4;U-266/70: 158.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA008129: AB_1848963, HPA028288: AB_10612110" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (8.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (5.44e-2)" "unprognostic (6.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "prognostic unfavorable (4.23e-8)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.16e-1)" 22.9 7.4 14.2 68.5 11.3 277.6 13.4 10.1 21.5 10.4 9.0 12.5 11.5 5.6 2.3 8.9 14.1 18.5 12.7 20.8 9.0 8.4 8.5 54.6 69.4 16.2 11.2 3.4 6.5 6.8 16.3 12.2 15.5 10.4 7.3 1.3 16.2 3.3 4.7 9.5 36.7 8.2 11.1 104.9 13.7 4.2 17.2 49.7 9.0 6.2 38.7 21.4 10.5 16.3 16.9 32.2 0.3 1.7 0.3 7.0 1.7 2.0 4.3 11.8 8.8 1.5 7.2 51.4 16.2 0.6 12.4 2.7 0.0 0.4 3.9 91.1 4.4 29.8 51.0 2.7 32.6 78.6 100.6 5.4 1.4 15.6 6.7 16.4 0.3 55.8 2.7 190.8 8.8 10.9 138.4 80.7 1.6 2.1 1.0 86.2 11.3 92.7 3.3 2.1 10.0 4.8 9.9 1.7 4.0 2.6 9.2 62.7 4.0 0.7 11.1 1.9 73.3 158.9 75.7 52.2 1.4 62.8 2.5 11.1 6.5 11.3 8.6 7.4 5.7 4.5 6.6 9.4 5.6 5.1 4.4 5.8 28.4 7.2 5.9 3.3 8.1 5.3 14.2 11.3 10.1 21.5 20.8 9.0 16.2 11.2 15.5 11.1 17.2 16.3 7.2 3.2 3.0 0.0 108.1 6.1 2.9 0.9 2.2 4.9 3.3 4.7 2.5 1.5 1.1 1.8 0.0 0.6 160.0 0.7 0.0 1.5 2.5 0.7 4.3 5.7 1.2 34.9 12.8 0.9 1.2 12.9 4.6 1.2 22.9 0.2 6.1 1.5 45.3 3.3 10.3 0.4 0.0 77.4 141.6 0.7 5.3 115.5 44.4 9.4 132.8 0.9 152.4 0.5 1.0 0.5 0.1 0.0 109.8 1.9 0.2 0.8 1.0 1.6 6.6 9.3 2.4 0.8 3.5 0.6 6.1 2.5 134.6 0.2 0.5 1.4 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043194 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 317.7;Langerhans cells: 402.9;monocytes: 433.2;Oligodendrocytes: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 137.7;JURKAT: 143.2;MOLT-4: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Vesicles "HPA019635: AB_2732423, HPA019691: AB_2670231, HPA022119: AB_2670897, HPA067742: " "unprognostic (2.86e-1)" "unprognostic (2.59e-3)" "unprognostic (1.22e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.30e-3)" "unprognostic (9.10e-2)" "unprognostic (2.90e-1)" "unprognostic (6.17e-2)" "unprognostic (9.26e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (8.45e-5)" "unprognostic (6.84e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" 21.8 11.9 51.2 57.8 73.7 40.6 16.4 77.4 53.4 32.5 22.2 107.3 15.0 50.0 17.0 39.4 34.8 27.8 15.1 47.0 62.5 16.4 18.4 25.4 78.1 67.6 69.1 22.1 8.1 10.7 17.7 16.3 65.8 41.4 29.6 12.6 16.3 44.1 24.1 25.9 37.6 46.8 55.9 60.9 29.6 17.3 69.9 111.0 33.4 13.2 74.3 68.4 26.8 86.6 42.5 19.3 34.9 40.8 21.0 25.8 29.5 23.7 20.2 17.6 14.7 20.3 16.2 82.9 20.4 44.5 20.8 20.7 33.0 21.6 17.6 137.7 9.8 22.8 22.8 13.8 35.8 62.3 75.1 18.7 9.3 32.6 19.5 25.6 26.1 143.2 5.4 1.1 16.4 34.0 140.1 60.8 27.5 5.7 32.6 31.9 28.3 24.1 22.1 23.0 5.5 17.6 43.3 42.9 16.5 33.3 30.0 28.3 31.9 16.6 20.7 30.5 15.0 16.4 64.4 3.8 20.0 42.2 25.2 13.2 5.1 9.6 10.8 5.6 9.3 12.7 9.7 10.3 5.8 7.7 8.9 8.6 9.3 6.0 6.5 6.9 10.9 4.5 51.2 73.7 77.4 53.4 47.0 62.5 67.6 69.1 65.8 55.9 69.9 86.6 27.2 35.3 25.2 317.7 180.4 33.1 21.3 12.8 21.6 20.2 42.5 24.6 14.8 15.7 29.8 22.0 52.1 18.6 217.2 28.3 19.6 22.6 1.7 46.2 38.8 38.3 18.1 31.3 65.6 17.3 24.5 38.8 26.5 78.7 80.4 9.2 71.0 18.4 43.6 28.6 107.8 8.7 20.3 221.2 402.9 5.5 46.6 131.1 76.5 95.5 433.2 42.8 223.5 69.4 522.1 21.8 19.8 51.6 147.9 67.8 0.2 15.0 42.3 29.5 59.2 19.9 41.0 26.5 45.4 26.7 41.1 63.9 233.7 7.1 16.2 42.3 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 266.4;prostate: 76.0" "Cell type enriched" "Detected in some" 8 "Oligodendrocytes: 367.6" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;RPMI-8226: 1.7;SK-BR-3: 1.8;TIME: 1.3;WM-115: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.8 1.1 17.3 0.9 37.3 0.7 4.8 27.1 27.7 1.9 7.9 0.7 266.4 1.7 0.9 1.5 3.5 10.2 0.5 18.3 22.4 13.5 35.5 1.3 0.9 32.7 28.4 1.0 0.3 0.2 0.0 0.3 31.5 76.0 0.5 4.0 52.8 0.6 0.2 1.7 82.9 1.0 24.1 2.4 1.1 0.8 31.1 0.1 1.0 0.2 0.6 1.4 0.3 59.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.1 2.3 0.2 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.1 1.7 0.0 0.0 0.2 0.7 0.0 1.8 0.3 0.2 0.3 0.0 1.3 0.1 0.9 0.2 0.1 0.0 0.2 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.3 37.3 27.1 27.7 18.3 22.4 32.7 28.4 31.5 24.1 31.1 59.3 0.5 0.0 0.6 0.0 0.0 0.3 0.7 0.1 0.6 0.0 8.2 7.0 0.3 0.0 1.9 0.0 0.0 0.0 0.5 0.0 7.9 0.0 5.2 2.1 0.5 5.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 2.8 0.0 0.0 2.9 25.9 0.1 0.0 1.0 1.1 0.0 0.3 0.0 1.4 1.5 0.2 3.6 1.0 0.0 17.4 0.0 0.0 367.6 0.0 1.2 0.4 0.0 43.0 0.8 32.4 0.1 0.6 0.0 0.0 0.4 1.1 1.5 1.5 0.9 0.0 0.2 0.5 0.2 0.6 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Group enriched" "Detected in some" 4 "Endothelial cells: 17.1;Fibroblasts: 46.3;Smooth muscle cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 12.8;BJ hTERT+: 27.9;HHSteC: 26.5;U-2197: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" 3.6 0.2 6.0 10.2 5.3 0.0 1.2 4.8 5.4 16.2 2.9 61.2 8.9 2.7 1.1 10.1 1.8 15.0 0.8 4.5 4.8 2.1 3.2 34.1 3.2 5.9 5.2 0.7 1.3 1.1 0.4 23.1 6.0 25.8 10.8 0.2 1.2 5.4 0.2 0.3 21.2 11.7 5.1 0.6 26.3 0.7 7.0 0.1 5.4 1.4 1.5 49.9 11.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 27.9 3.8 1.3 0.0 0.1 0.0 0.0 1.2 2.6 0.0 2.2 0.0 3.3 0.0 1.5 0.0 2.1 0.0 26.5 0.0 2.3 2.8 0.0 4.5 0.5 0.4 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.9 11.9 0.0 0.0 0.0 0.0 2.5 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.3 4.8 5.4 4.5 4.8 5.9 5.2 6.0 5.1 7.0 5.1 2.0 0.0 0.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.3 17.1 0.0 0.0 0.0 0.0 0.4 46.3 1.1 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.0 0.4 0.0 0.1 18.7 0.0 1.3 0.6 0.3 1.2 0.1 0.1 0.0 0.6 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.5;salivary gland: 66.2;stomach 1: 28.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 56.4;Club cells: 69.4;Distal enterocytes: 110.0;Gastric mucus-secreting cells: 83.6;Ionocytes: 57.0;Paneth cells: 75.5;Proximal enterocytes: 182.4;Undifferentiated cells: 62.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 63.6;OE19: 76.1" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.2 0.6 0.8 6.2 0.9 0.3 1.7 5.5 1.2 16.0 0.0 23.5 44.5 1.1 0.1 26.0 2.6 13.5 0.5 0.9 0.0 1.0 0.3 0.9 0.5 0.2 0.1 1.1 5.2 0.1 2.0 0.1 0.3 1.4 19.8 0.9 66.2 2.9 0.7 4.8 21.9 0.8 0.0 0.6 28.9 0.8 0.4 0.6 0.7 0.0 6.6 6.3 9.7 0.6 2.0 1.5 0.3 0.9 0.0 0.0 0.2 0.2 0.0 0.0 0.0 7.2 63.6 0.7 0.5 0.0 0.3 10.6 0.0 0.0 0.0 0.5 0.5 0.6 0.6 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.0 1.0 0.0 1.2 0.1 0.8 0.1 0.5 0.7 1.5 0.4 76.1 0.3 0.5 0.2 3.0 0.0 0.6 3.4 0.5 0.3 0.6 0.1 0.4 9.5 0.1 0.3 0.4 0.4 0.5 0.2 0.7 0.5 0.1 0.3 0.4 0.2 1.1 0.1 0.1 0.4 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.4 0.1 0.5 0.2 0.1 0.4 0.6 0.2 0.8 0.9 5.5 1.2 0.9 0.0 0.2 0.1 0.3 0.0 0.4 0.6 0.5 0.0 0.6 0.7 0.6 0.9 2.3 56.4 5.7 2.5 6.1 3.0 0.8 32.9 69.4 20.2 2.1 0.1 0.4 110.0 1.9 4.7 0.5 8.4 2.7 0.7 11.4 0.0 2.3 46.5 0.0 0.5 83.6 23.9 0.0 0.1 0.0 0.1 0.1 0.0 1.4 42.1 57.0 0.3 0.3 0.2 0.0 0.3 1.8 0.0 0.3 0.5 2.1 0.5 1.2 31.8 75.5 0.0 0.2 2.9 182.4 0.1 37.8 4.2 0.0 1.2 2.4 0.3 0.2 9.9 1.4 0.1 0.8 0.3 62.9 19.4 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.7;intestine: 72.3;retina: 79.3;salivary gland: 84.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.7;Intestinal goblet cells: 78.7;Pancreatic endocrine cells: 49.0;Paneth cells: 88.9;Proximal enterocytes: 85.2;Undifferentiated cells: 65.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 46.3;hTCEpi: 6.9;OE19: 20.6;RH-30: 14.8;SK-BR-3: 7.1" HPA046966 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.5 0.0 0.4 12.6 0.6 0.7 1.2 0.5 0.7 25.9 0.5 72.3 47.7 0.3 0.0 158.7 1.3 22.4 0.2 0.4 1.2 9.8 2.3 5.2 0.1 0.8 0.5 0.1 9.1 0.0 0.6 0.1 0.7 2.2 44.5 79.3 84.2 8.5 0.1 3.2 56.3 2.8 0.2 0.2 20.8 4.0 0.6 0.2 0.0 0.0 15.9 3.0 53.2 0.7 46.3 0.0 0.2 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 5.2 0.0 0.6 0.0 0.0 2.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 6.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 20.6 0.0 0.0 14.8 1.6 0.0 0.6 0.0 0.2 0.0 7.1 0.2 0.1 0.1 0.4 0.0 0.2 0.1 0.1 0.3 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.6 0.5 0.7 0.4 1.2 0.8 0.5 0.7 0.2 0.6 0.7 0.1 0.0 4.8 0.3 1.1 0.0 3.0 23.6 0.0 1.8 1.7 0.3 0.3 11.5 36.4 0.0 0.0 0.1 0.0 154.7 0.0 43.2 4.9 1.1 0.1 0.5 13.8 0.0 0.1 14.2 0.4 0.0 18.3 0.6 8.9 0.1 0.0 0.4 0.0 0.0 0.0 78.7 14.2 0.0 0.0 8.7 0.0 0.2 0.0 1.0 0.0 1.9 0.0 0.0 0.1 49.0 88.9 0.0 0.1 0.9 85.2 16.5 22.8 34.9 0.0 0.0 1.5 0.5 0.2 6.5 0.0 0.3 0.5 0.0 65.6 27.3 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.4;kidney: 36.1;salivary gland: 45.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 35.6;Intestinal goblet cells: 39.4;Paneth cells: 21.5;Proximal enterocytes: 101.4;Proximal tubular cells: 45.3;Undifferentiated cells: 29.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "Hep G2: 10.5;RPMI-8226: 4.0" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 51000 "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.1 0.0 0.1 2.6 0.1 0.4 1.7 0.2 0.1 17.3 0.4 17.3 28.6 0.3 0.0 79.4 0.6 9.3 0.0 0.1 0.1 36.1 12.4 0.2 0.1 0.1 0.1 0.0 3.7 0.0 0.0 0.0 0.1 0.2 11.6 2.0 45.7 2.5 0.0 0.1 27.0 0.4 0.1 0.1 4.8 0.2 0.1 0.0 0.0 0.0 6.7 0.0 26.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.2 10.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 4.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.5 0.0 0.7 0.0 0.4 3.5 0.0 0.4 3.7 1.9 0.3 18.6 15.7 1.8 0.0 0.2 0.3 35.6 3.9 6.8 0.3 0.6 0.7 0.3 4.9 0.0 0.1 0.4 0.1 0.3 0.0 0.7 0.0 0.2 0.7 5.1 0.1 0.0 0.1 39.4 8.2 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.9 0.0 0.5 0.1 2.7 21.5 0.0 0.0 0.2 101.4 45.3 6.4 11.5 0.0 0.3 0.7 1.0 0.6 3.6 0.1 0.0 0.5 0.1 29.0 1.7 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.5;fallopian tube: 13.7;liver: 17.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Collecting duct cells: 31.3;Endometrial ciliated cells: 11.1;Glandular and luminal cells: 10.8;Respiratory ciliated cells: 48.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "T-47d: 5.1" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in some" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (6.12e-5)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (9.19e-3)" "unprognostic (4.77e-3)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (3.71e-1)" "unprognostic (2.86e-4)" "unprognostic (3.84e-2)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 3.6 14.5 0.2 0.3 0.9 0.3 0.2 13.7 0.0 1.5 1.0 0.1 3.5 17.1 2.0 0.0 0.0 0.0 0.1 1.0 6.3 0.8 0.0 0.0 1.5 0.4 0.0 2.1 1.7 1.5 0.0 0.6 0.0 0.0 0.0 0.4 1.3 0.1 2.5 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 22.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 6.3 0.0 0.0 6.8 31.3 0.0 0.5 0.0 0.0 3.9 0.5 0.0 11.1 0.7 0.0 0.0 0.0 0.0 1.5 0.0 7.3 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 48.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917899-45995824 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 263.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" 16.7 13.0 10.5 9.7 12.0 6.5 13.4 9.6 9.4 23.1 11.3 42.0 8.0 25.6 10.3 21.3 15.4 18.7 66.8 8.6 10.3 10.7 10.8 14.7 8.6 15.5 10.8 23.1 12.7 20.3 7.6 8.2 14.8 19.3 10.7 33.0 14.9 22.9 263.3 19.3 14.4 28.2 15.1 10.2 20.4 3.3 11.9 10.5 16.5 104.6 8.2 39.6 16.9 15.1 10.8 10.3 3.0 13.0 27.9 21.8 4.9 10.2 23.7 13.1 14.6 5.6 9.3 7.9 5.6 14.2 12.7 7.9 8.5 17.0 15.7 3.3 9.0 11.4 8.7 6.3 19.0 8.8 7.9 24.3 16.7 21.1 20.5 20.3 26.7 13.4 7.4 11.3 9.5 6.7 9.0 5.5 4.5 8.8 9.8 3.1 8.3 4.4 15.9 37.2 2.2 3.4 6.4 20.0 17.6 4.4 9.7 5.7 20.8 5.0 5.9 17.0 5.7 6.4 4.4 2.7 17.2 11.1 9.6 0.7 0.5 0.3 2.0 0.5 2.7 0.2 1.2 2.1 0.2 0.2 0.5 0.7 0.4 1.5 0.3 1.3 1.2 0.7 10.5 12.0 9.6 9.4 8.6 10.3 15.5 10.8 14.8 15.1 11.9 15.1 9.5 28.9 13.7 12.4 4.8 4.1 4.8 5.6 3.4 11.2 8.5 4.8 89.3 8.6 13.0 16.5 35.5 4.3 8.7 6.8 3.9 8.8 0.1 6.4 8.9 9.3 9.6 6.9 0.8 8.3 2.2 14.0 12.8 11.2 2.5 14.9 11.4 9.2 4.1 0.0 0.8 7.6 2.0 5.8 4.6 1.6 12.8 5.1 10.6 10.3 4.0 20.0 6.2 8.0 21.2 11.0 2.5 17.7 3.0 17.3 8.7 6.2 18.6 37.1 6.6 20.8 12.8 2.3 0.8 8.4 4.1 2.9 12.7 6.1 6.2 7.9 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 152.3;esophagus: 171.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 169.0;Breast myoepithelial cells: 113.2;Club cells: 83.1;Endometrial ciliated cells: 146.0;Glandular and luminal cells: 464.0;Urothelial cells: 146.6" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.7" "Cell line enhanced" "Detected in many" "A-431: 215.1;EFO-21: 236.8;HeLa: 166.8;PC-3: 331.3;SuSa: 418.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB014883 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" 4.5 3.6 10.4 7.3 10.5 9.9 152.3 15.8 16.2 13.1 5.4 4.2 15.4 48.6 19.0 171.5 12.9 27.3 5.4 7.6 23.0 6.1 7.1 14.7 5.7 12.5 6.1 3.9 23.8 2.0 2.0 9.1 10.6 12.7 4.9 42.1 35.8 16.6 13.7 19.0 16.2 2.6 2.7 7.4 27.4 8.3 10.4 4.7 6.1 2.7 42.2 5.4 29.4 17.9 215.1 9.9 10.1 7.0 0.7 4.3 23.8 3.8 1.5 0.5 0.6 38.1 23.6 3.3 236.8 1.1 2.3 75.7 6.4 0.5 0.6 3.5 7.6 14.1 166.8 5.7 0.8 5.1 11.2 1.6 3.0 2.8 1.8 8.0 1.4 13.4 57.6 26.5 0.4 6.7 9.5 4.7 84.5 3.7 331.3 13.7 6.6 8.2 13.8 11.6 8.2 4.0 76.5 3.9 2.2 418.8 4.2 2.4 8.8 19.1 69.3 15.7 15.7 10.0 6.7 6.3 2.6 13.9 2.9 11.8 1.9 6.1 0.4 1.5 1.1 0.3 0.4 0.3 0.6 0.7 0.5 0.5 4.5 0.2 5.7 0.9 0.6 2.3 10.4 10.5 15.8 16.2 7.6 23.0 12.5 6.1 10.6 2.7 10.4 17.9 1.1 3.2 0.6 0.0 0.9 0.0 14.9 44.4 0.0 0.0 169.0 113.2 0.7 51.5 83.1 1.8 0.0 5.2 2.3 0.0 0.0 10.4 0.0 146.0 48.8 3.8 0.0 0.0 0.3 13.8 0.6 2.4 2.0 464.0 0.0 0.0 0.0 0.1 2.3 0.0 0.2 0.3 12.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.6 0.1 0.0 0.0 24.2 0.1 0.1 34.0 0.0 0.0 0.2 5.9 0.0 0.0 4.5 0.0 5.7 2.7 0.0 0.6 146.6 GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;retina: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 214.6;Inhibitory neurons: 333.1;Oligodendrocyte precursor cells: 986.7;Oligodendrocytes: 398.2" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 43.8;U-251 MG: 12.0;WM-115: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA060775: AB_2684358" "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" 2.1 5.0 8.4 0.2 9.9 0.1 1.2 30.1 7.7 1.7 1.0 0.4 0.2 1.8 1.2 0.1 0.4 0.5 0.2 7.6 17.9 0.1 0.0 2.1 0.0 9.3 12.3 0.5 0.3 0.0 1.7 0.4 11.4 2.0 0.3 9.9 4.1 1.4 1.0 0.6 0.3 1.0 9.5 0.0 0.4 0.6 10.8 0.0 0.0 0.0 0.0 0.7 0.2 11.4 0.0 5.2 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 5.5 0.0 0.0 0.1 2.8 0.0 5.0 1.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.6 0.0 0.1 0.1 0.5 1.0 0.0 0.0 0.2 7.3 0.2 6.9 0.0 0.3 1.0 0.0 0.0 7.5 43.8 0.1 0.1 0.0 0.7 0.0 0.1 0.0 0.1 1.9 0.1 12.0 0.6 0.1 0.0 7.2 0.0 33.5 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 9.9 30.1 7.7 7.6 17.9 9.3 12.3 11.4 9.5 10.8 11.4 0.2 25.6 1.1 13.1 0.0 0.1 0.0 0.0 0.0 14.4 0.2 0.3 1.0 0.0 1.3 0.0 52.1 0.1 0.0 0.1 0.0 0.0 1.9 0.4 21.5 0.7 3.5 0.0 214.6 0.2 0.0 2.8 0.0 0.3 0.0 0.1 0.0 0.0 0.1 72.3 333.1 1.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.8 0.0 0.9 0.0 986.7 398.2 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.6 0.0 0.2 0.5 0.8 0.6 0.0 0.1 0.0 0.2 4.2 0.9 0.0 GARRE1 KIAA0355 ENSG00000166398 "Granule associated Rac and RHOG effector 1" O15063 19 34254552-34355566 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 126.8;Cardiomyocytes: 15.7;Cytotrophoblasts: 23.8;Extravillous trophoblasts: 25.1;Syncytiotrophoblasts: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014570 Uncertain Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA014570: AB_1852307" "unprognostic (1.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-3)" "unprognostic (9.05e-2)" "unprognostic (8.27e-2)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.34e-1)" "unprognostic (7.73e-3)" "unprognostic (2.96e-2)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" 18.8 5.6 5.0 7.2 6.7 3.4 16.8 7.3 4.5 10.8 6.7 7.8 5.4 11.0 3.0 8.0 10.1 9.5 12.0 3.6 5.6 8.2 7.3 12.4 9.1 7.0 7.0 9.4 10.4 10.8 7.7 23.3 6.6 8.3 5.6 8.1 7.4 6.4 15.4 10.3 8.2 8.6 5.2 16.1 6.6 7.1 7.1 8.5 10.9 17.0 7.5 8.0 9.9 10.3 3.4 10.2 8.9 4.6 6.0 5.7 11.6 7.6 6.2 5.7 8.4 8.1 3.9 7.7 16.4 7.1 7.1 2.4 6.6 3.6 6.2 11.0 5.8 4.7 3.9 6.2 7.6 2.1 3.7 6.7 6.2 7.5 11.0 22.6 23.7 4.3 14.4 3.8 6.2 1.8 1.4 1.9 6.8 4.6 3.7 3.4 6.2 4.1 4.8 3.8 10.3 8.5 8.7 33.9 10.9 12.9 2.7 3.8 19.7 19.5 7.2 5.0 8.1 6.4 9.5 2.4 3.7 0.8 9.7 0.0 0.7 0.0 0.8 1.4 1.3 2.3 1.8 0.8 0.8 2.8 1.6 1.0 2.2 1.5 2.1 1.1 3.0 0.8 5.0 6.7 7.3 4.5 3.6 5.6 7.0 7.0 6.6 5.2 7.1 10.3 126.8 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 23.8 10.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 25.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 34.1 2.3 0.0 0.0 0.0 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 12.6;choroid plexus: 7.4;heart muscle: 8.8;liver: 21.5;pituitary gland: 23.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Cardiomyocytes: 4.9;Fibroblasts: 5.2;Horizontal cells: 5.0;Smooth muscle cells: 3.7" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 0.8 0.3 8.9 0.3 8.3 0.2 0.7 8.1 9.5 2.8 7.4 0.5 0.1 1.2 0.8 0.4 1.2 0.5 8.8 8.2 11.0 1.2 21.5 0.4 0.2 9.0 9.9 1.4 1.8 0.1 23.9 1.6 9.1 1.2 0.2 1.0 0.3 0.7 0.2 0.7 0.5 0.3 8.3 0.6 0.6 0.4 12.6 0.1 0.5 0.1 0.2 1.1 2.0 7.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.2 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.3 2.3 0.7 0.1 0.1 0.3 2.0 0.4 0.8 0.1 0.0 0.1 0.0 0.3 8.9 8.3 8.1 9.5 8.2 11.0 9.0 9.9 9.1 8.3 12.6 7.9 0.3 0.0 0.0 0.7 0.3 1.1 0.7 0.0 1.2 5.0 0.1 0.8 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.5 2.4 0.0 1.8 0.0 0.2 5.2 0.0 0.0 0.0 2.4 0.0 0.4 0.7 5.0 2.4 0.0 0.0 0.0 0.7 0.3 0.9 0.1 0.0 1.0 0.0 2.8 0.0 0.5 1.0 0.1 0.1 2.2 0.2 1.7 0.0 0.1 0.0 0.8 0.0 0.6 3.7 0.5 1.1 0.0 0.1 0.8 0.3 0.5 0.0 0.7 GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial ciliated cells: 79.1;Glandular and luminal cells: 105.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 44.2;Hep G2: 19.7;SK-MEL-30: 17.1;SuSa: 21.4" "Region enriched" "Detected in all" 4 "basal ganglia: 61.1" "Low region specificity" "Detected in all" HPA026776 Approved Approved "Golgi apparatus" No No 750000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" 0.6 0.3 0.7 1.0 0.6 0.3 10.1 2.5 1.1 4.2 4.5 3.6 5.2 1.4 0.2 1.4 0.8 1.5 6.6 0.8 1.1 5.7 5.1 3.9 1.8 1.2 1.0 0.3 1.3 0.4 1.4 2.6 1.4 13.5 2.0 0.3 4.2 0.3 0.7 1.4 5.8 1.6 0.9 1.5 5.9 2.5 0.9 0.5 1.2 1.8 2.4 1.0 0.7 1.0 6.3 4.9 1.5 4.8 0.0 0.0 9.6 0.0 4.1 1.1 0.5 11.0 5.2 3.5 44.2 0.0 3.2 0.3 0.4 5.1 2.9 3.1 1.8 0.5 2.6 19.7 0.0 1.7 4.7 0.0 0.0 0.5 0.0 2.4 9.1 0.0 0.4 0.0 0.4 0.0 0.0 4.0 4.4 0.0 3.6 0.2 3.8 6.0 16.0 2.9 4.0 1.2 0.0 14.4 17.1 21.4 0.3 0.8 6.4 0.8 0.5 0.0 5.0 0.1 0.0 2.4 0.8 0.3 2.3 1.9 1.1 0.5 0.1 0.8 0.0 0.7 0.1 0.1 0.8 0.4 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.3 0.7 0.6 2.5 1.1 0.8 1.1 1.2 1.0 1.4 0.9 0.9 1.0 1.4 76.9 32.4 1.0 9.5 4.6 6.6 15.5 9.6 5.1 30.5 16.1 18.4 2.8 28.6 7.3 0.0 27.9 6.4 15.5 11.7 2.9 4.3 79.1 5.5 11.0 2.4 25.9 0.7 24.7 2.1 2.0 16.8 105.5 2.5 0.0 12.8 32.0 15.8 3.3 11.8 5.6 6.1 7.7 9.4 8.2 0.3 7.8 49.8 52.5 11.1 2.4 0.0 18.6 1.1 12.0 11.9 0.0 1.0 16.6 44.3 13.4 27.9 0.6 0.0 0.7 2.2 6.2 27.6 11.2 1.7 10.9 3.1 0.0 16.3 8.1 GCSAM "GCET2, HGAL, MGC40441" ENSG00000174500 "Germinal center associated signaling and motility" Q8N6F7 3 112120839-112133270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 29.3;skin 1: 16.4" "Cell type enhanced" "Detected in some" "B-cells: 10.9;dendritic cells: 6.7;Langerhans cells: 5.3;monocytes: 23.3;T-cells: 9.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Daudi: 132.8;U-698: 76.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA002473 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "HPA002473: AB_1078960" "unprognostic (8.23e-4)" "unprognostic (1.64e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (2.33e-1)" "unprognostic (4.17e-3)" "unprognostic (9.20e-2)" "unprognostic (8.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.69e-3)" "unprognostic (1.97e-1)" "unprognostic (5.78e-2)" "unprognostic (3.32e-2)" "unprognostic (3.77e-1)" "unprognostic (3.43e-2)" "unprognostic (2.35e-2)" "unprognostic (2.38e-2)" 0.5 0.2 0.0 6.4 0.1 1.7 0.6 0.0 0.1 0.3 0.2 1.9 2.1 0.2 0.2 1.8 0.4 1.5 0.9 0.1 0.1 1.2 0.5 2.2 22.2 0.0 0.1 0.1 4.0 0.0 0.7 0.3 0.0 0.9 0.9 0.0 1.3 0.3 0.2 16.4 3.5 0.3 0.0 5.0 2.8 0.4 0.0 17.7 3.3 0.1 29.3 1.3 1.0 0.0 1.9 0.3 0.5 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 3.6 0.2 132.8 0.1 0.0 0.8 3.5 0.0 2.4 0.0 2.7 0.8 0.9 0.8 0.6 0.0 0.6 0.0 0.0 2.4 0.0 0.2 0.8 0.0 1.0 0.2 7.5 0.0 0.1 12.6 0.0 1.0 0.7 0.7 14.6 1.1 0.0 0.0 1.3 0.1 0.2 0.8 0.7 0.3 0.9 1.8 0.0 1.0 1.2 0.6 0.0 0.0 0.7 0.0 76.4 0.2 0.2 0.3 9.0 0.0 0.0 2.2 0.1 0.5 10.2 11.3 5.8 6.7 12.1 10.4 5.7 0.4 0.6 0.0 3.7 1.9 3.8 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 10.9 0.1 0.8 0.3 0.0 0.0 0.1 1.8 0.4 0.0 0.2 0.0 0.0 0.3 6.7 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.2 0.3 0.5 1.2 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 1.6 5.3 0.0 0.0 1.6 0.0 0.0 23.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 3.2 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.0 2.0 0.4 0.1 9.6 0.0 0.0 0.7 GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;prostate: 5.5" "Cell type enriched" "Detected in some" 24 "granulocytes: 223.3" "Cancer enriched" "Detected in single" 13 "prostate cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.4" "Immune cell enriched" "Detected in single" 661 "basophil: 227.7" "Lineage enriched" "Detected in single" 661 "granulocytes: 227.7" "Group enriched" "Detected in some" 71 "HEL: 151.8;HMC-1: 564.8" "Low region specificity" "Detected in all" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA027507: AB_10600756, HPA027510: AB_2672309" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (4.07e-3)" "unprognostic (3.48e-2)" "unprognostic (1.72e-1)" "unprognostic (2.76e-4)" "unprognostic (3.21e-1)" "unprognostic (6.14e-2)" "unprognostic (5.42e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.81e-1)" "unprognostic (9.51e-3)" "unprognostic (3.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" 0.5 0.2 0.4 0.8 0.4 1.8 1.0 6.4 0.7 0.7 0.4 1.2 1.5 0.8 0.5 1.1 0.3 1.4 0.2 0.3 0.4 0.1 0.2 2.1 0.3 0.4 0.3 0.1 0.4 0.1 0.0 0.3 1.2 5.5 1.5 1.2 0.3 0.4 0.2 0.7 1.4 0.6 0.1 0.4 0.9 3.4 0.4 0.7 0.3 0.7 0.2 0.7 0.3 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.8 0.8 0.2 0.1 0.0 0.1 151.8 0.2 0.0 0.0 0.3 564.8 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.3 0.3 5.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.4 0.0 0.0 0.3 0.2 0.0 2.3 0.1 0.4 227.7 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.4 6.4 0.7 0.3 0.4 0.4 0.3 1.2 0.1 0.4 1.2 0.0 0.0 4.4 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.9 0.0 9.1 0.0 0.1 0.6 0.0 5.0 0.4 0.0 0.0 0.3 0.0 0.0 223.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.7 7.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.3 1.7 0.0 0.6 0.0 1.4 0.1 0.0 0.2 GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 721.1;Fibroblasts: 395.9;Langerhans cells: 155.5;Smooth muscle cells: 359.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 83.0;U-266/70: 140.6;U-87 MG: 104.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" 56.1 58.4 10.9 35.6 9.6 2.6 36.7 8.3 12.3 57.9 38.7 105.7 16.6 97.2 9.7 59.5 39.0 229.6 63.4 11.0 20.8 32.3 20.2 33.1 23.8 12.7 12.2 19.9 15.7 2.9 27.3 7.3 11.0 31.7 35.9 44.4 13.1 16.8 4.2 10.9 31.1 77.3 8.4 21.9 48.0 3.8 12.2 12.6 23.6 10.8 14.2 90.6 33.6 12.3 1.6 6.1 2.7 0.6 22.9 30.4 0.4 16.1 83.0 21.4 29.8 2.3 4.1 0.0 1.0 6.1 40.1 0.5 2.7 1.4 28.0 12.2 1.4 0.0 0.6 0.0 3.0 0.0 26.3 13.1 0.1 34.1 18.9 24.4 0.9 1.4 0.7 2.7 12.7 0.8 1.0 0.2 4.0 3.4 18.3 0.0 4.9 0.1 7.8 0.0 20.4 12.1 0.0 0.1 2.8 3.4 2.0 0.1 1.2 29.4 8.1 19.2 33.4 140.6 0.9 0.1 104.7 0.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 10.9 9.6 8.3 12.3 11.0 20.8 12.7 12.2 11.0 8.4 12.2 12.3 18.4 6.4 25.4 22.2 8.9 68.1 85.7 9.6 721.1 26.8 8.6 35.1 90.8 4.3 4.0 1.8 18.8 0.4 4.1 8.2 0.0 7.3 4.7 26.0 49.2 19.0 25.0 0.0 0.7 0.4 1.4 395.9 54.0 50.3 13.4 1.0 7.1 0.1 2.8 30.3 3.4 2.6 2.0 0.6 155.5 0.3 3.4 43.3 92.5 0.0 0.8 41.9 0.0 0.0 0.3 2.7 17.2 5.7 46.5 20.2 2.1 2.6 1.2 21.4 32.9 55.5 359.5 1.3 1.1 24.1 49.9 3.4 33.4 0.9 4.2 10.6 GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 53.7;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in some" "dendritic cells: 14.2;Intestinal goblet cells: 12.4;NK-cells: 11.3;Plasma cells: 8.6;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 61.9;HMC-1: 47.5;NB-4: 64.7;THP-1: 127.7;U-937: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB011197: AB_532302" "unprognostic (5.67e-4)" "unprognostic (8.67e-3)" "prognostic favorable (5.68e-5)" "unprognostic (4.88e-3)" "unprognostic (3.57e-2)" "unprognostic (5.86e-3)" "unprognostic (2.06e-1)" "unprognostic (3.87e-3)" "unprognostic (1.26e-3)" "unprognostic (4.47e-3)" "unprognostic (5.20e-2)" "unprognostic (1.72e-1)" "unprognostic (6.80e-6)" "unprognostic (2.63e-1)" "unprognostic (8.27e-2)" "unprognostic (3.97e-1)" "unprognostic (4.37e-2)" 1.0 0.5 0.1 5.1 0.2 53.7 0.9 0.1 0.1 0.6 0.3 3.6 4.7 0.6 0.5 0.5 0.7 1.9 0.3 0.1 0.1 0.5 1.0 2.8 6.9 0.3 0.1 0.5 9.4 0.2 0.5 0.2 0.2 0.8 4.5 0.0 1.0 0.3 0.2 0.3 5.7 0.4 0.2 7.0 3.2 0.9 0.2 31.2 0.9 0.0 4.4 1.7 0.6 0.2 1.4 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.1 0.1 1.0 10.3 0.1 0.7 0.0 0.5 0.4 1.2 0.0 0.2 0.0 2.5 1.6 0.2 5.3 0.1 61.9 47.5 0.0 0.0 0.1 0.1 0.3 0.1 17.1 0.4 15.3 0.1 2.1 39.5 64.7 0.0 0.1 0.2 7.8 2.7 3.4 0.0 0.7 0.1 0.1 0.3 0.1 0.3 0.1 0.0 127.7 0.0 0.0 1.5 0.1 0.2 22.2 1.6 4.0 0.0 261.3 0.0 0.0 0.0 0.4 2.1 0.0 1.0 0.0 0.9 1.4 0.0 0.0 0.3 1.9 0.0 0.1 0.0 0.8 0.3 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.2 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 14.2 1.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.1 0.2 0.0 0.1 1.4 0.0 0.1 0.0 0.1 12.4 0.0 0.8 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 11.3 0.0 0.1 0.4 0.0 0.0 8.6 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.2 0.5 3.9 0.0 0.0 0.0 16.4 0.1 0.4 0.0 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.5;Breast glandular cells: 33.1;Fibroblasts: 51.2;Hepatocytes: 42.2;Oligodendrocyte precursor cells: 91.0;Skeletal myocytes: 100.1" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 44.7;BJ hTERT+ SV40 Large T+ RasG12V: 77.2;EFO-21: 46.5;fHDF/TERT166: 89.3;HBF TERT88: 63.2;MCF7: 59.5;U-251 MG: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" 10.9 3.4 7.2 4.2 14.9 0.0 23.2 2.6 9.5 9.9 0.3 18.3 1.7 4.9 20.5 6.9 17.2 5.6 4.8 9.7 18.0 6.0 16.0 2.8 4.0 7.8 28.5 4.5 6.6 2.7 3.2 0.0 7.2 4.5 3.9 3.2 6.0 5.4 4.3 7.2 8.2 4.8 6.2 3.9 8.2 3.1 7.6 4.1 2.8 13.9 6.4 7.0 9.2 6.1 0.1 3.7 12.2 0.0 0.0 0.1 0.0 7.9 0.4 44.7 77.2 0.0 0.0 0.0 46.5 89.3 0.0 0.0 0.1 0.0 63.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 11.5 0.0 3.9 0.0 9.1 0.0 0.0 5.6 59.5 7.6 0.0 5.0 0.0 0.0 0.0 1.9 0.0 5.0 0.0 1.6 0.1 0.0 0.0 0.1 2.1 0.4 0.0 0.4 0.0 0.4 0.1 53.5 0.0 0.0 0.1 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 14.9 2.6 9.5 9.7 18.0 7.8 28.5 7.2 6.2 7.6 6.1 6.1 0.0 0.0 40.5 0.5 5.7 0.0 0.0 1.8 4.1 33.1 11.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 13.2 0.0 0.2 3.2 6.0 0.0 5.1 13.5 0.0 51.2 3.1 0.0 6.3 0.1 0.4 42.2 0.0 0.0 6.6 0.0 0.0 1.0 9.6 12.8 8.1 1.0 5.4 1.9 0.0 12.6 0.0 91.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.5 0.0 100.1 16.7 0.1 10.4 0.7 4.5 0.0 0.7 0.1 0.0 0.2 GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 159.9;U-698: 170.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "CAB034422: AB_2110748, HPA043313: AB_2678421, HPA063634: AB_2685067" "unprognostic (1.27e-1)" "prognostic favorable (1.71e-5)" "unprognostic (8.53e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (7.82e-3)" "unprognostic (3.88e-2)" "unprognostic (2.15e-3)" "unprognostic (8.55e-2)" "prognostic favorable (3.91e-5)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (3.89e-2)" "unprognostic (2.08e-1)" 15.1 36.3 13.0 32.0 13.1 37.6 19.9 18.6 14.8 20.7 25.2 16.5 10.0 16.1 19.6 17.9 18.4 13.4 18.5 13.8 15.3 26.9 16.4 34.1 72.9 11.7 12.9 34.0 54.3 29.2 26.0 17.6 11.9 27.4 15.8 79.3 37.6 21.3 25.5 21.1 33.6 14.9 10.8 44.2 25.7 12.4 17.8 37.2 36.2 19.0 87.3 16.3 18.7 12.3 18.8 22.9 29.6 26.1 16.5 17.9 25.3 19.7 20.0 15.2 19.3 32.1 18.9 159.9 31.4 21.1 4.3 28.7 49.1 25.8 19.4 25.1 45.6 28.8 29.5 51.2 16.2 48.0 18.2 18.7 22.7 20.8 9.7 22.1 22.0 12.8 50.3 23.0 19.8 29.8 17.0 31.9 39.6 18.3 20.2 108.3 38.4 41.2 24.8 25.6 21.1 25.3 18.3 27.0 27.1 31.5 23.7 59.7 24.5 18.1 19.6 20.3 18.5 42.0 41.8 170.8 16.5 32.2 20.6 0.2 4.2 7.0 3.1 4.3 3.2 16.2 3.9 3.7 4.9 21.6 4.0 4.0 0.5 3.1 4.0 15.9 4.5 3.1 13.0 13.1 18.6 14.8 13.8 15.3 11.7 12.9 11.9 10.8 17.8 12.3 11.7 48.1 41.4 28.7 102.3 34.2 33.6 16.5 39.3 73.2 25.0 26.0 27.3 21.5 17.6 22.0 114.7 23.0 80.6 7.3 25.4 19.3 22.0 25.4 17.6 19.0 17.6 9.9 44.2 18.9 40.7 17.3 15.3 37.3 9.5 88.5 12.5 16.1 69.1 6.7 61.5 12.6 12.2 26.1 19.7 30.8 24.5 37.7 26.6 36.5 87.9 23.8 23.7 26.2 8.3 16.2 6.1 26.4 36.1 20.7 8.7 21.5 16.2 153.3 19.7 16.0 16.3 30.5 60.5 25.4 14.6 22.7 34.8 56.8 11.9 18.6 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Endothelial cells: 2.2;granulocytes: 3.8;Macrophages: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Group enriched" "Detected in some" 6 "AN3-CA: 4.3;HEL: 1.3;SH-SY5Y: 4.9" HPA023262 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" 33.4 18.5 15.4 10.1 18.9 68.2 40.4 12.7 19.9 17.2 14.4 14.9 12.0 10.7 7.4 24.2 10.1 23.1 18.7 16.4 15.3 5.7 15.0 21.9 25.7 13.9 15.2 7.6 5.0 4.8 41.7 13.7 6.5 15.4 0.5 133.2 15.3 5.0 13.6 16.1 12.5 14.1 40.4 8.7 4.1 16.0 9.9 5.1 13.4 10.4 21.4 14.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 17.9 0.0 0.7 0.0 0.0 12.7 0.0 0.0 0.0 1.2 0.1 0.4 27.5 0.0 7.2 15.4 18.9 12.7 19.9 16.4 15.3 13.9 15.2 13.7 14.1 16.0 14.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.3;Endothelial cells: 83.5;Hepatic stellate cells: 92.1;Kupffer cells: 75.2;monocytes: 37.4;NK-cells: 91.6;T-cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.4;HUVEC TERT2: 124.9;MOLT-4: 43.3;TIME: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" 42.0 9.4 9.7 33.9 9.7 2.5 21.8 9.7 10.6 14.9 8.0 12.0 13.6 19.3 7.3 8.4 16.9 14.7 29.1 8.0 9.5 12.4 12.7 38.8 50.2 11.4 10.5 5.7 5.2 8.0 3.3 32.3 11.3 6.4 12.2 0.6 7.8 10.0 24.7 6.4 18.7 25.8 10.9 64.0 11.6 3.2 11.6 29.3 14.2 34.7 33.9 16.5 6.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 6.3 0.0 0.0 0.0 0.4 18.4 0.1 0.0 0.0 0.0 0.0 124.9 0.5 0.0 4.6 0.0 0.0 43.3 5.4 0.0 0.0 0.0 4.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.8 35.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 13.0 0.0 11.6 58.1 2.1 112.9 75.1 127.2 0.4 104.3 120.2 22.1 0.3 108.3 103.0 8.0 217.3 60.2 0.7 105.7 163.5 9.7 9.7 9.7 10.6 8.0 9.5 11.4 10.5 11.3 10.9 11.6 10.1 95.3 0.0 1.1 0.0 3.1 3.8 0.1 0.0 0.6 0.0 1.1 1.0 7.4 0.0 0.0 0.0 0.0 0.2 24.5 0.1 0.0 0.0 0.4 0.1 0.2 83.5 0.0 19.4 0.0 0.2 0.3 3.4 0.0 0.2 2.5 0.3 92.1 1.7 30.6 0.0 0.0 0.1 0.0 75.2 6.5 2.2 1.2 20.0 1.8 13.1 37.4 0.1 91.6 0.0 0.1 0.1 0.0 0.0 2.9 0.1 0.0 0.2 0.7 0.4 0.0 2.6 2.2 0.3 0.1 0.4 3.1 0.4 41.2 1.2 0.0 0.3 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 234.2;Sertoli cells: 664.0;Smooth muscle cells: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 74.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047981 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047981: AB_2680228" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.48e-1)" "unprognostic (5.24e-3)" "prognostic favorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (8.17e-2)" "unprognostic (6.83e-2)" "unprognostic (8.81e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.47e-2)" "unprognostic (3.74e-2)" "unprognostic (3.82e-3)" "unprognostic (7.96e-3)" 79.4 20.4 10.1 9.3 11.0 0.3 61.5 9.8 15.1 26.6 9.0 14.7 2.8 33.8 5.5 7.5 40.0 17.3 83.6 10.5 9.6 35.8 17.3 40.7 11.3 10.3 10.2 18.0 7.0 10.6 6.4 61.6 10.6 18.8 3.8 0.8 10.1 10.7 34.7 14.8 13.9 15.2 10.2 9.9 12.9 5.4 10.2 2.7 39.8 35.2 5.4 28.1 22.4 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.1 11.0 9.8 15.1 10.5 9.6 10.3 10.2 10.6 10.2 10.2 9.9 90.4 0.0 0.0 0.3 0.6 9.7 1.9 0.2 1.2 0.2 1.1 1.5 9.0 1.5 0.6 3.7 0.0 0.2 0.7 0.0 0.0 11.0 0.1 3.1 0.5 81.4 15.6 2.7 0.0 0.0 0.1 7.7 2.6 4.9 0.0 0.5 234.2 1.8 0.3 0.0 0.0 0.0 0.0 6.3 10.7 1.1 0.9 2.2 19.6 1.0 0.6 0.1 0.0 0.0 0.0 1.0 0.0 12.8 0.2 3.0 0.0 0.1 1.2 0.7 664.0 4.4 306.3 0.2 1.2 0.7 8.7 0.0 1.3 1.6 0.1 5.2 GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 100.9;liver: 335.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 114.4;Hepatocytes: 286.4;Proximal enterocytes: 118.8;Proximal tubular cells: 68.9;Undifferentiated cells: 66.1" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 143.2;SK-MEL-30: 155.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" 0.1 0.0 27.1 3.7 63.2 0.0 6.4 76.5 37.6 8.8 12.7 33.9 44.0 1.7 22.5 0.3 27.4 41.5 0.0 27.3 40.9 42.9 335.7 2.4 0.0 90.6 64.4 0.1 83.0 0.0 0.1 0.0 76.0 11.6 23.8 0.0 37.7 7.5 0.0 0.9 34.4 1.8 50.0 0.1 16.4 10.2 56.9 0.0 0.1 0.1 0.0 0.4 0.1 100.9 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 25.5 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.3 0.0 5.1 0.2 0.0 0.2 0.0 0.0 155.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.1 63.2 76.5 37.6 27.3 40.9 90.6 64.4 76.0 50.0 56.9 100.9 0.0 0.0 4.8 0.3 0.8 0.6 0.7 0.5 0.0 0.0 7.7 2.4 0.1 114.4 2.7 9.2 0.0 0.0 0.1 50.2 9.8 34.1 0.3 8.2 3.4 0.6 9.6 8.0 0.2 58.9 0.0 0.1 15.8 29.0 4.5 0.0 3.3 286.4 0.0 0.0 0.2 29.4 2.0 4.8 0.4 0.4 0.3 0.8 23.2 0.0 0.6 0.0 0.0 1.0 51.3 32.3 53.4 0.4 0.0 2.6 118.8 68.9 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 0.0 1.0 0.0 66.1 2.8 GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.0" "Group enriched" "Detected in many" 4 "Sertoli cells: 157.8;Smooth muscle cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071788 Uncertain "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Cell Junctions, Cytosol" "HPA071788: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" 9.5 0.7 3.1 3.6 2.8 0.8 5.2 10.1 3.8 9.2 5.5 28.6 1.6 24.7 2.9 2.7 5.3 5.4 11.8 2.3 1.4 2.2 0.7 7.2 2.7 2.1 2.9 2.2 1.4 3.4 0.6 40.0 2.6 8.9 2.9 1.0 1.1 18.6 4.6 2.0 5.3 32.7 1.3 0.7 7.6 8.8 4.0 1.6 6.7 5.9 2.0 11.4 6.1 3.0 44.5 21.9 62.0 18.9 8.3 10.6 20.5 50.3 36.6 50.0 52.6 12.4 24.7 0.5 2.3 46.4 69.9 10.1 29.2 13.7 70.8 0.5 19.8 0.4 12.1 1.6 3.8 0.3 1.7 8.8 1.6 37.0 11.8 20.4 17.1 9.6 1.8 0.5 31.4 0.4 6.7 4.3 29.5 0.1 16.2 39.5 73.8 0.3 11.4 16.8 10.2 21.5 4.6 0.5 16.2 41.3 10.9 8.0 12.3 43.8 39.3 22.2 38.9 0.4 11.3 32.5 15.9 0.3 40.7 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.2 0.2 1.0 0.5 0.1 0.2 0.1 0.1 3.1 2.8 10.1 3.8 2.3 1.4 2.1 2.9 2.6 1.3 4.0 3.0 11.7 0.0 0.0 0.7 0.2 2.0 1.7 0.5 0.0 3.4 0.6 1.4 25.1 0.0 0.2 1.8 2.1 0.5 0.4 0.1 0.0 1.5 1.5 1.4 14.9 19.5 0.0 0.0 8.1 0.0 2.6 6.3 0.0 3.0 0.0 9.4 4.2 0.3 1.5 13.5 1.4 0.0 0.0 0.3 4.2 0.3 1.5 1.2 3.6 1.0 0.6 0.2 0.0 0.0 0.3 0.6 0.0 2.2 0.0 1.4 0.0 0.3 0.2 0.9 157.8 4.8 101.1 15.6 28.4 0.6 3.0 0.5 0.8 7.8 0.1 1.3 GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" 42.7 36.8 25.0 17.4 26.3 9.0 40.3 24.0 25.7 53.3 17.3 44.5 17.3 57.8 22.4 30.9 46.7 20.4 50.5 24.7 27.5 42.6 25.6 38.2 16.3 27.0 29.0 69.0 58.1 34.3 38.9 24.9 25.2 37.5 18.7 20.3 36.1 24.9 53.8 35.2 36.4 29.9 25.0 35.1 36.3 40.6 29.5 20.0 43.1 16.4 18.9 42.3 40.8 30.0 38.4 52.2 44.7 43.3 113.7 113.2 42.8 45.0 64.2 48.6 68.3 34.4 116.0 22.8 59.8 102.9 35.8 71.1 30.1 62.1 80.1 10.3 26.1 17.9 37.8 54.3 70.5 29.3 12.6 68.0 32.8 63.6 66.3 91.3 100.8 54.8 19.0 24.9 44.2 70.0 14.1 26.0 34.7 81.2 20.6 33.9 32.6 59.5 31.6 17.1 15.8 23.3 87.3 24.9 25.0 47.7 28.2 36.5 79.1 46.1 40.9 48.2 30.3 47.4 51.2 41.1 86.3 22.5 46.6 3.2 16.7 13.3 19.1 15.7 19.2 11.6 23.8 20.9 18.5 10.1 28.2 22.6 7.3 15.4 19.9 18.4 21.0 19.0 25.0 26.3 24.0 25.7 24.7 27.5 27.0 29.0 25.2 25.0 29.5 30.0 52.8 64.1 50.7 114.3 46.4 27.1 27.2 33.0 55.8 68.5 35.6 35.6 79.5 77.2 39.7 51.5 146.0 78.0 75.6 33.5 7.9 39.9 39.7 49.2 79.3 62.0 38.6 25.0 133.4 42.5 43.6 101.4 38.7 58.0 3.8 91.0 75.3 40.7 50.1 70.7 155.3 31.9 24.4 68.8 42.1 28.1 96.9 44.4 42.7 62.8 64.8 59.6 111.2 97.5 137.3 40.8 28.8 114.3 100.2 33.6 47.8 44.2 44.3 57.9 92.1 84.6 59.9 89.2 87.9 30.5 21.6 75.2 72.4 72.4 32.9 26.4 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 22.1;Peritubular cells: 33.8;Proximal tubular cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" 16.3 23.4 4.4 2.5 4.1 0.1 11.4 5.2 3.9 22.3 3.3 19.2 1.5 20.9 0.7 4.9 17.3 5.6 30.9 3.1 3.8 41.5 3.2 30.6 1.6 5.6 5.6 27.5 13.2 2.3 18.9 4.4 4.3 21.7 0.4 0.7 9.8 4.0 3.0 7.1 7.4 3.3 4.4 4.5 11.9 5.3 5.5 0.2 19.4 0.4 0.5 20.2 11.4 2.5 6.1 12.3 2.0 4.8 1.5 7.2 4.3 6.1 5.3 2.3 1.6 3.2 5.1 0.0 10.8 6.0 2.2 3.7 1.2 5.6 0.1 8.9 0.3 0.0 10.9 1.9 6.9 0.0 0.9 4.1 1.2 1.9 0.9 2.6 1.9 0.1 0.5 2.0 1.3 4.0 0.0 1.2 4.6 0.7 2.2 11.7 2.6 6.7 0.4 0.0 0.9 4.6 6.1 2.9 1.7 0.6 8.2 1.0 3.2 3.2 6.0 36.8 1.9 1.4 0.9 1.5 1.4 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 4.1 5.2 3.9 3.1 3.8 5.6 5.6 4.3 4.4 5.5 2.5 4.8 16.0 9.8 8.5 0.0 5.6 5.4 8.7 1.8 10.6 3.5 2.4 5.9 15.7 5.6 12.9 4.2 0.9 0.1 0.0 19.6 11.8 0.2 1.8 9.0 6.9 0.0 0.0 2.1 8.3 0.9 18.3 0.5 2.1 0.0 2.6 6.8 0.7 0.4 6.7 3.2 0.2 2.0 0.3 6.1 0.9 22.1 0.8 3.6 5.6 1.0 10.4 0.0 4.0 1.3 10.3 0.0 33.8 0.0 5.1 0.0 21.7 3.1 7.3 0.0 8.2 14.6 0.2 3.4 0.7 2.8 1.1 0.7 0.1 0.0 2.8 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 204.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 41.3;Hepatocytes: 54.9;Inhibitory neurons: 31.6" "Cancer enriched" "Detected in single" 4 "liver cancer: 1.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Cell line enhanced" "Detected in some" "A-431: 7.6;Daudi: 42.8;Hep G2: 7.4;SCLC-21H: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" 0.2 1.6 4.0 0.2 3.2 0.1 1.3 4.4 11.4 0.5 0.0 0.6 0.3 0.9 2.3 1.5 4.1 0.2 0.2 3.4 5.0 1.9 204.9 1.4 0.9 4.7 1.6 0.8 21.2 5.6 5.8 0.0 4.8 1.4 1.6 11.2 1.5 2.3 0.0 2.8 0.5 0.5 0.5 0.5 1.4 0.5 1.9 1.3 1.4 0.0 1.5 0.6 0.7 8.2 7.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 4.3 1.2 42.8 0.5 0.0 0.0 0.8 0.0 6.5 0.0 0.0 6.0 0.0 0.4 7.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 3.2 1.2 0.5 0.0 0.1 6.6 3.9 3.4 12.6 0.5 1.3 0.3 0.0 1.0 4.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.8 0.8 1.7 0.4 0.0 0.3 1.8 2.2 0.0 0.0 0.0 0.0 0.5 0.7 4.0 3.2 4.4 11.4 3.4 5.0 4.7 1.6 4.8 0.5 1.9 8.2 0.2 0.0 2.7 5.5 2.3 1.7 4.8 4.6 10.8 10.7 0.9 1.7 0.0 0.0 4.5 0.0 6.2 0.2 0.1 0.1 7.9 0.5 0.0 0.3 0.2 0.5 1.2 8.0 41.3 2.0 0.0 0.5 1.1 0.2 1.3 0.3 2.5 54.9 0.1 3.3 31.6 0.1 0.0 1.6 0.7 0.0 0.9 0.1 1.8 3.7 0.2 3.1 0.0 8.0 3.3 0.7 0.1 0.0 0.9 1.3 0.0 0.6 1.7 10.2 0.0 0.3 0.2 0.6 1.5 5.5 1.1 0.3 1.1 0.0 0.3 1.3 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238587-16295549 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 358.6;tongue: 205.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Endometrial ciliated cells: 118.2;Erythroid cells: 367.1;Melanocytes: 92.5" "Cancer enhanced" "Detected in all" "melanoma: 95.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Group enriched" "Detected in all" 6 "granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6" "Cell line enhanced" "Detected in many" "HEL: 193.1;HMC-1: 314.7;SK-MEL-30: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain NA NA 950000 "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA000904: AB_1078998, HPA021476: AB_1849858" "unprognostic (2.74e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (4.97e-3)" "unprognostic (3.52e-2)" "unprognostic (1.05e-1)" "unprognostic (3.06e-1)" "prognostic favorable (8.07e-4)" "unprognostic (4.12e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.15e-1)" "unprognostic (2.86e-1)" "prognostic favorable (2.94e-5)" "unprognostic (3.01e-1)" "unprognostic (1.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.17e-1)" 10.0 23.3 28.5 2.8 31.9 29.7 6.5 32.4 21.6 6.6 35.7 15.5 2.7 13.3 16.5 5.3 56.9 3.7 101.7 19.6 38.2 25.5 5.9 9.1 2.5 36.8 45.6 38.0 18.3 14.2 24.9 7.8 35.0 63.1 3.4 2.2 21.5 9.0 358.6 12.4 6.0 9.9 39.7 12.5 36.5 52.3 41.3 6.5 4.4 205.0 1.6 5.2 3.7 33.2 0.0 0.0 0.3 0.0 2.7 2.1 0.1 3.9 15.7 27.2 55.2 1.6 0.4 0.0 8.8 6.0 19.1 0.1 6.7 0.8 4.5 0.0 5.0 193.1 0.1 0.0 11.8 0.8 314.7 3.7 2.8 8.5 0.0 22.2 49.5 0.7 43.9 0.3 4.8 3.8 0.2 4.1 2.0 0.2 7.5 0.0 41.9 0.0 36.1 5.4 9.4 1.2 1.9 3.2 74.4 12.1 3.0 1.4 12.5 0.4 0.2 1.3 7.5 2.3 0.0 0.0 0.9 20.3 21.8 14.9 3.3 0.4 0.7 5.0 1.2 0.2 0.1 0.5 1.5 1.5 0.0 0.2 3.3 9.6 1.7 1.5 0.0 16.0 28.5 31.9 32.4 21.6 19.6 38.2 36.8 45.6 35.0 39.7 41.3 33.2 4.6 0.0 0.0 8.8 1.3 5.1 30.2 0.7 0.6 0.7 5.3 3.8 52.8 35.8 2.7 20.2 0.0 25.3 0.6 1.4 86.1 12.4 16.0 118.2 8.7 6.8 7.8 367.1 3.8 4.9 2.8 10.2 9.2 78.9 55.3 38.9 17.9 5.0 8.9 0.0 11.5 3.2 4.1 6.4 2.1 16.3 34.5 47.4 92.5 2.8 9.2 9.8 2.1 3.0 1.7 3.0 1.2 80.9 1.4 69.9 2.2 15.5 6.4 0.8 0.0 12.6 7.4 6.5 17.2 1.3 1.8 6.8 3.5 19.4 3.8 8.3 GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 330.6;Proximal enterocytes: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA048886: AB_2680544" "unprognostic (4.64e-3)" "unprognostic (2.21e-1)" "unprognostic (3.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (6.26e-2)" "unprognostic (7.85e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.48e-11)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" 33.5 32.5 36.4 16.2 31.2 8.3 32.6 53.8 35.3 31.7 18.9 66.7 117.5 42.4 12.7 28.7 44.5 20.0 51.7 33.5 27.3 40.4 26.2 34.7 7.5 30.3 29.6 32.5 33.9 26.3 29.8 22.3 28.6 40.4 38.7 11.0 33.3 47.1 54.2 34.4 139.3 28.7 26.6 21.4 34.9 50.6 31.3 8.5 32.9 39.2 7.0 38.8 27.0 31.1 56.1 31.2 27.9 48.5 41.7 28.4 30.9 53.8 53.7 71.8 57.8 41.7 27.3 12.0 29.2 76.4 43.6 39.0 37.8 42.7 44.3 30.1 21.9 3.3 35.7 23.6 42.2 3.8 11.8 36.9 36.8 48.4 29.2 36.9 57.8 3.4 27.8 1.9 49.1 25.8 3.0 14.4 20.5 38.4 29.4 23.2 26.4 11.9 33.8 40.8 66.0 40.7 38.3 45.2 27.2 18.9 33.3 7.9 50.0 45.7 33.3 85.4 73.5 1.3 3.9 7.9 33.0 2.9 52.3 2.5 1.4 0.3 0.7 0.7 0.8 0.9 0.5 0.6 0.2 1.1 1.2 0.9 5.1 0.5 1.5 2.3 0.1 0.3 36.4 31.2 53.8 35.3 33.5 27.3 30.3 29.6 28.6 26.6 31.3 31.1 62.3 32.1 24.1 5.2 3.5 32.6 9.5 15.4 13.6 22.7 43.2 47.9 17.8 35.8 12.6 27.6 37.5 13.2 2.4 330.6 7.9 21.4 45.2 26.9 23.0 33.9 54.6 5.2 8.8 25.4 13.5 25.3 29.6 26.1 4.5 24.1 58.2 28.5 9.0 45.4 11.3 84.1 26.4 9.1 16.4 20.0 50.1 5.1 23.2 11.2 1.1 29.0 0.0 7.1 14.1 36.1 96.0 80.5 1.2 16.0 323.0 18.9 35.4 15.8 19.7 28.5 30.5 23.7 8.9 20.6 41.2 20.4 2.0 22.1 94.9 13.4 GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Horizontal cells: 124.5;Rod photoreceptor cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 18.3;SCLC-21H: 39.0;SH-SY5Y: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" 9.2 6.6 30.7 2.8 35.9 1.6 8.4 27.4 36.2 5.4 27.8 14.8 1.7 10.1 2.8 5.0 10.2 11.2 2.4 33.6 24.5 2.0 0.5 1.4 1.8 29.6 30.7 8.9 1.6 7.5 24.1 0.3 32.0 8.5 1.6 33.0 1.8 17.2 1.4 1.4 3.2 11.9 27.0 4.7 11.5 4.3 29.0 0.5 1.5 2.1 1.2 8.0 3.6 35.7 0.1 2.0 6.8 14.3 0.0 0.0 0.4 9.2 18.3 8.9 6.0 0.1 0.1 17.7 0.6 0.8 12.2 0.3 8.4 0.3 6.4 2.2 7.0 1.1 10.2 13.1 0.6 0.0 1.4 0.0 0.3 0.2 0.5 2.2 0.2 1.0 0.2 5.4 0.2 6.4 0.1 0.1 4.1 0.5 5.5 0.1 6.8 2.7 0.1 0.1 39.0 24.0 2.0 4.4 1.9 0.8 1.9 0.2 0.0 7.2 8.2 2.0 0.2 6.6 12.0 9.2 3.7 0.6 2.8 0.9 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.0 2.0 30.7 35.9 27.4 36.2 33.6 24.5 29.6 30.7 32.0 27.0 29.0 35.7 32.1 3.2 0.0 4.9 0.7 0.3 0.3 0.4 0.0 12.6 0.8 1.7 1.6 7.2 0.7 3.7 8.4 0.0 0.7 0.3 0.0 2.0 1.5 1.6 0.5 5.0 4.8 2.7 11.0 1.6 0.0 1.1 1.5 0.4 0.0 2.1 2.2 0.4 0.1 124.5 11.0 0.3 2.0 0.0 1.7 2.1 4.1 18.6 1.8 1.0 1.2 19.3 1.0 2.0 16.5 0.7 0.0 4.1 0.1 0.3 0.1 0.9 1.3 37.7 0.0 9.0 2.1 2.0 4.2 0.0 0.4 0.0 0.6 0.9 0.2 0.1 GNG4 ENSG00000168243 "G protein subunit gamma 4" P50150 1 235547685-235650754 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.9;ovary: 32.1;pituitary gland: 32.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 24.4;Enteroendocrine cells: 43.0;Inhibitory neurons: 43.3;Intestinal goblet cells: 16.2;Oligodendrocyte precursor cells: 25.1;Prostatic glandular cells: 24.1;Proximal enterocytes: 24.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cell line enhanced" "Detected in many" "NTERA-2: 151.4;SCLC-21H: 158.4;SH-SY5Y: 222.8;U-2197: 67.2" "Region enriched" "Detected in all" 6 "olfactory bulb: 469.3" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.50e-3)" "unprognostic (8.33e-3)" "unprognostic (7.14e-2)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (4.94e-2)" "unprognostic (2.22e-2)" "unprognostic (3.10e-2)" "unprognostic (3.47e-2)" "unprognostic (3.49e-1)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (2.56e-9)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.68e-3)" "unprognostic (5.01e-3)" 1.4 11.3 20.0 1.7 25.6 0.1 0.6 7.9 21.0 4.7 3.1 3.6 2.5 9.5 0.1 14.4 3.3 0.5 0.1 15.4 40.9 1.9 0.3 0.1 5.7 21.3 28.2 32.1 5.1 0.0 32.0 1.7 25.4 22.6 3.0 2.4 2.0 0.7 0.1 0.5 5.3 6.6 18.9 0.1 3.1 1.7 33.6 4.9 0.3 0.0 3.4 1.0 2.4 7.3 37.2 2.0 26.4 0.0 0.0 1.3 2.4 0.1 0.4 3.3 4.5 0.1 1.5 0.0 0.3 11.2 9.0 3.3 28.4 1.2 6.7 19.4 10.2 0.1 0.7 14.4 0.4 0.2 12.1 2.4 0.2 0.4 0.9 0.0 0.0 2.0 0.3 0.1 2.1 0.1 7.6 1.2 151.4 0.1 0.1 0.0 13.8 0.7 0.0 1.1 158.4 222.8 0.9 0.3 3.2 1.7 0.2 5.3 0.0 1.7 5.0 67.2 5.2 3.5 0.2 0.0 4.9 0.1 44.5 1.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 20.0 25.6 7.9 21.0 15.4 40.9 21.3 28.2 25.4 18.9 33.6 7.3 0.1 0.0 0.0 2.9 0.2 0.5 2.6 0.3 0.0 2.3 0.2 0.9 0.5 0.0 1.0 0.0 0.0 7.7 2.7 1.6 0.0 0.0 1.1 1.5 24.4 1.4 43.0 0.0 2.3 9.0 10.0 1.7 0.0 0.8 0.0 3.8 0.0 0.0 0.9 1.7 43.3 16.2 4.1 0.0 3.6 1.0 0.3 1.1 0.0 4.7 1.0 0.4 0.0 25.1 0.8 1.6 1.3 0.4 0.1 24.1 24.5 4.9 0.2 1.3 0.0 0.2 1.6 1.8 4.4 0.0 0.0 6.3 1.1 0.3 4.6 1.5 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960754-42963880 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "liver: 296.5;pancreas: 600.1" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 842.9" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;SCLC-21H: 9.5;T-47d: 6.1" "Region enriched" "Detected in some" 4 "cerebellum: 15.7" "Low region specificity" "Detected in many" HPA027501 Enhanced Approved Cytosol NA NA 390000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favorable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.9 0.9 2.3 1.3 2.5 3.8 7.1 2.8 2.4 0.8 2.0 0.7 0.2 0.8 2.2 0.6 1.3 0.5 4.7 2.2 2.2 0.9 296.5 2.0 1.0 1.1 1.0 1.9 600.1 0.2 8.4 0.4 1.1 20.3 0.3 2.2 9.8 1.2 1.8 0.9 1.6 0.5 0.9 2.9 50.8 0.7 1.9 1.8 1.9 0.4 1.2 0.8 0.7 2.1 0.4 0.3 1.4 3.9 0.4 0.1 0.2 0.3 1.6 0.6 0.9 0.0 0.1 1.3 0.1 0.3 0.7 0.4 0.2 0.2 0.2 1.6 1.2 1.0 0.9 8.5 0.0 0.9 1.8 0.3 0.0 0.3 0.1 0.9 0.0 3.0 1.2 1.5 0.2 1.8 1.6 3.0 0.1 0.4 0.4 1.4 1.3 0.8 0.6 0.2 9.5 1.3 0.1 1.3 0.6 0.4 6.1 2.8 0.3 0.7 0.7 0.4 0.8 1.0 1.0 1.1 0.1 1.6 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.0 0.7 0.0 0.1 2.3 2.5 2.8 2.4 2.2 2.2 1.1 1.0 1.1 0.9 1.9 2.1 0.3 0.0 2.2 5.5 2.8 0.3 5.2 0.7 0.0 1.7 10.2 14.7 5.4 24.3 0.2 1.8 0.0 0.1 1.7 0.0 3.9 0.5 0.2 1.6 0.2 2.2 0.0 77.9 18.4 0.9 0.1 0.3 0.5 0.8 0.0 2.6 24.3 842.9 0.7 1.7 18.2 0.0 6.1 28.9 0.7 0.1 0.9 1.1 0.0 11.2 0.3 0.2 0.0 7.1 4.7 0.6 0.0 2.6 0.5 17.9 0.3 3.4 4.6 0.3 0.0 0.2 0.6 0.6 0.7 0.0 0.1 0.1 3.0 0.0 0.2 1.9 GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 396.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 362.8;Early spermatids: 339.0;Gastric mucus-secreting cells: 245.6;Ionocytes: 325.5;Late spermatids: 391.6;Pancreatic endocrine cells: 282.9;Paneth cells: 265.2;Undifferentiated cells: 245.6" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.9;classical monocyte: 3.6;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.2;non-classical monocyte: 4.2;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 372.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA 81000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" 22.2 159.8 72.5 33.8 78.8 6.6 39.5 69.2 84.5 70.0 99.0 195.7 235.1 40.1 15.7 13.6 38.1 131.0 12.7 72.1 93.8 74.7 19.0 14.7 9.7 73.4 76.1 36.9 41.6 37.6 36.4 17.2 69.9 143.2 163.9 25.5 173.4 10.5 9.4 14.9 61.3 28.4 80.1 41.7 396.2 17.4 108.0 45.4 68.1 4.8 5.6 38.3 14.9 79.2 146.0 139.5 102.4 116.7 129.3 74.3 108.0 64.8 46.6 99.9 80.5 69.4 282.9 2.7 62.6 126.2 96.6 109.4 63.7 64.1 71.9 5.0 101.2 45.3 89.1 3.4 76.8 67.3 34.9 113.4 34.2 94.1 34.0 124.9 172.9 21.2 28.7 4.2 57.3 68.4 8.3 49.6 161.9 188.9 99.6 42.9 116.9 21.8 166.0 61.2 115.1 72.0 88.2 189.0 73.8 66.1 106.7 68.1 110.5 25.9 72.6 79.3 78.3 372.3 37.4 0.9 112.2 29.8 57.8 1.9 3.6 0.4 3.5 2.6 0.4 0.6 0.2 0.5 0.4 0.6 0.4 0.7 4.2 0.7 4.2 1.5 0.1 1.8 72.5 78.8 69.2 84.5 72.1 93.8 73.4 76.1 69.9 80.1 108.0 79.2 13.8 9.6 15.3 30.3 1.7 2.3 10.8 11.3 4.6 20.1 41.4 21.1 4.9 80.1 80.9 35.0 8.4 8.4 10.7 362.8 25.4 168.4 339.0 78.0 49.8 20.5 73.1 11.2 47.0 222.2 35.0 30.4 245.6 56.8 1.3 65.9 8.6 11.1 11.8 67.3 43.2 95.5 325.5 5.0 2.6 391.6 18.3 6.6 23.2 6.5 6.9 16.9 12.3 82.0 19.3 282.9 265.2 13.2 3.2 72.6 71.8 16.0 78.6 6.7 0.0 13.5 19.5 10.3 38.7 2.9 1.0 6.4 5.2 60.7 245.6 29.1 GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 131.3;Proximal enterocytes: 206.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 18.0;CAPAN-2: 20.0;Hep G2: 25.9;MCF7: 43.5;OE19: 16.1;RT4: 27.7;SK-BR-3: 27.2" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" 0.3 0.1 6.1 0.4 9.2 0.0 5.3 7.0 5.3 10.9 3.9 5.6 47.4 0.3 10.7 0.5 3.3 1.6 0.1 4.3 11.2 16.2 190.7 8.3 0.1 4.7 5.3 0.1 22.3 18.3 30.4 3.5 4.7 5.3 5.0 1.5 3.4 2.1 0.3 0.5 45.5 0.3 4.5 0.1 8.2 2.6 11.6 0.8 0.7 0.0 0.2 13.1 0.4 2.8 0.5 8.2 0.0 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 18.0 20.0 0.0 0.7 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.0 25.9 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 43.5 0.0 0.1 4.0 16.1 0.2 0.0 0.1 0.4 8.5 27.7 1.3 1.8 0.8 27.2 0.1 0.7 8.9 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.1 9.2 7.0 5.3 4.3 11.2 4.7 5.3 4.7 4.5 11.6 2.8 0.1 0.0 19.5 0.3 0.1 0.0 12.7 2.6 2.8 1.7 7.2 4.7 0.2 40.0 5.1 16.5 0.0 13.3 0.1 7.0 13.7 29.2 0.9 0.5 0.1 0.3 10.3 0.0 2.2 19.1 0.5 1.1 8.2 2.0 1.3 1.4 1.8 131.3 1.3 1.7 0.7 7.8 2.0 1.6 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 4.5 0.1 18.7 5.6 0.0 0.0 15.0 206.8 14.7 0.3 0.2 0.0 0.3 0.3 2.9 0.9 1.4 0.1 26.4 0.5 0.2 12.5 20.5 GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 966 "pancreas: 35381.6" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 504.1" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" NA NA 41000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" 7.1 1.9 0.2 0.9 0.2 0.7 3.8 0.6 0.4 2.5 0.4 3.9 36.6 2.1 0.2 3.9 1.4 18.7 6.5 0.3 0.2 33.4 5.0 1.5 2.1 0.2 0.6 15.4 35381.6 0.0 2.9 2.4 0.3 33.4 6.2 0.1 7.5 0.0 1.6 1.8 10.1 0.1 0.1 2.5 27.4 1.9 0.2 0.1 1.3 0.0 0.2 1.0 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.4 0.3 0.2 0.2 0.6 0.3 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 1.1 0.1 0.1 87.2 0.0 0.0 0.0 0.0 0.0 1.7 9.8 1.3 7.5 0.3 0.5 0.2 0.0 0.0 0.0 504.1 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.1 0.0 0.0 0.3 15.6 0.3 0.4 0.0 0.0 4.2 0.2 0.0 0.0 0.0 20.7 13.9 0.4 0.0 69.7 2.0 0.0 0.0 0.3 0.0 0.5 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 19.9 2.1 GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Alveolar cells type 2: 29.2;Astrocytes: 54.5;Extravillous trophoblasts: 36.2;Granulosa cells: 30.6;Proximal tubular cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 209.7;HAP1: 121.8;NTERA-2: 110.3;RPTEC TERT1: 276.6;SuSa: 242.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 190000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" 9.6 9.8 5.9 4.9 6.4 0.1 5.6 5.0 5.8 12.0 4.6 22.5 10.6 10.8 16.4 7.4 11.2 9.0 7.9 6.3 7.5 20.6 1.8 17.4 2.5 7.2 6.9 12.3 10.8 5.6 16.6 29.0 6.0 8.0 10.9 1.2 13.0 11.4 24.3 3.8 10.8 17.7 6.6 5.7 16.9 7.8 4.9 8.4 5.9 20.0 2.0 10.3 5.2 8.5 0.0 0.0 209.7 8.3 8.9 1.3 26.0 1.6 0.0 0.0 0.0 0.1 0.5 0.3 71.7 1.2 0.0 0.1 121.8 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 37.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 6.0 0.1 0.1 110.3 0.0 3.2 0.6 19.2 0.0 276.6 8.4 0.1 1.5 0.8 0.1 0.1 242.0 3.2 3.2 0.0 21.3 24.8 0.0 13.6 0.0 0.0 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.4 5.0 5.8 6.3 7.5 7.2 6.9 6.0 6.6 4.9 8.5 1.7 51.3 29.2 54.5 0.2 1.5 3.7 14.7 14.2 0.0 2.9 2.0 4.4 5.7 8.7 23.9 0.0 0.5 0.2 2.5 3.9 7.0 0.6 5.9 1.7 1.2 2.4 0.0 4.7 12.7 36.2 14.4 6.6 10.0 0.0 30.6 0.0 0.0 2.5 0.0 1.4 11.1 4.1 0.6 3.9 2.1 2.1 2.0 1.8 14.0 1.1 1.0 0.0 4.5 4.3 16.5 4.3 0.4 0.1 1.4 4.6 30.3 12.8 0.1 0.0 6.3 13.6 2.4 23.6 2.3 0.4 3.1 1.0 1.4 11.3 0.6 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 743.2;choroid plexus: 180.7;retina: 207.7" "Cell type enhanced" "Detected in many" "Astrocytes: 633.3;Excitatory neurons: 361.3;Melanocytes: 357.5;Muller glia cells: 1722.4;Oligodendrocyte precursor cells: 408.1;Oligodendrocytes: 1476.6" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 220 "plasmacytoid DC: 77.7" "Lineage enriched" "Detected in single" 268 "dendritic cells: 77.7" "Cell line enhanced" "Detected in many" "AF22: 154.8;AN3-CA: 150.1;ASC TERT1: 74.2;HSkMC: 110.0;SK-MEL-30: 154.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" 7.5 9.3 418.4 6.0 518.8 1.1 26.4 540.4 521.1 27.1 180.7 33.8 5.0 6.3 12.1 11.5 6.5 5.9 15.8 447.8 463.6 7.7 1.1 16.8 2.8 596.3 459.3 4.4 3.2 0.6 17.2 1.3 580.5 21.8 7.8 207.7 14.8 35.2 2.5 13.9 9.2 5.4 533.4 14.5 11.7 3.5 419.9 0.8 5.0 7.5 1.9 9.1 19.7 743.2 0.4 0.4 154.8 150.1 41.6 74.2 0.4 0.9 6.9 0.1 0.0 0.4 0.5 0.7 0.3 0.0 0.6 1.3 7.6 0.8 0.0 0.6 25.2 0.4 10.0 0.4 1.5 0.5 0.9 110.0 0.9 0.0 1.9 0.6 0.0 3.0 0.4 6.8 1.5 0.6 3.4 0.7 48.5 0.1 2.5 2.0 13.7 23.9 0.0 0.5 7.8 4.4 0.8 4.4 154.4 41.9 0.7 3.6 0.3 1.0 1.3 0.3 2.0 0.5 0.3 0.3 1.4 0.3 12.4 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 77.7 0.1 0.7 418.4 518.8 540.4 521.1 447.8 463.6 596.3 459.3 580.5 533.4 419.9 743.2 13.8 0.0 5.1 633.3 15.8 33.0 22.7 5.9 6.8 74.4 37.1 47.1 1.3 1.5 7.8 22.0 87.6 5.0 50.7 3.0 0.0 5.4 1.5 45.8 32.7 12.5 1.2 5.3 361.3 3.7 3.7 54.2 0.0 30.4 4.5 19.7 10.8 0.4 1.2 26.9 144.0 5.0 8.2 1.9 33.5 3.2 24.2 3.7 357.5 40.3 4.6 1722.4 50.4 408.1 1476.6 2.3 6.0 32.0 7.3 26.5 6.1 1.1 11.0 151.4 46.0 137.7 43.6 9.6 13.3 7.0 17.0 13.7 20.5 8.6 3.2 14.8 GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "B-cells: 23.6;Langerhans cells: 45.5;Macrophages: 30.2;monocytes: 19.1;NK-cells: 15.5;T-cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "HDLM-2: 26.9;Karpas-707: 26.6;THP-1: 8.2" "HPA029694, HPA029695" Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" 2.1 0.7 0.9 7.0 0.7 8.0 0.9 0.7 0.9 0.9 1.0 1.3 1.0 0.6 0.4 0.8 1.6 1.4 0.8 0.8 1.0 5.4 0.5 2.7 7.7 1.6 1.1 0.3 0.7 0.3 0.5 1.5 1.2 0.8 0.9 0.3 0.9 0.3 0.5 2.6 4.3 0.8 1.0 7.8 1.7 0.3 1.2 1.9 4.6 0.6 4.5 2.4 1.1 1.3 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.5 3.5 0.6 0.0 0.0 0.7 0.0 0.0 0.0 26.9 0.3 0.6 0.1 0.0 0.1 2.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 26.6 0.0 0.8 0.0 2.7 0.1 0.0 0.0 2.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 8.2 0.4 0.1 0.1 0.0 0.3 0.7 2.6 0.3 0.0 2.4 0.0 9.6 6.0 5.5 6.1 7.7 5.9 4.2 4.8 5.5 5.7 4.5 4.8 5.3 4.7 5.8 9.1 3.1 3.6 5.0 0.9 0.7 0.7 0.9 0.8 1.0 1.6 1.1 1.2 1.0 1.2 1.3 0.6 0.0 1.9 0.7 23.6 1.7 0.1 1.0 0.0 0.0 0.3 0.3 0.8 0.0 0.7 1.8 0.0 0.1 12.2 0.0 1.9 0.4 0.0 2.2 0.8 0.9 0.0 4.0 0.7 0.6 0.3 0.4 1.1 5.2 12.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.0 7.1 45.5 0.2 0.0 30.2 5.4 7.5 19.1 0.0 15.5 0.0 0.1 1.2 0.0 0.0 11.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 1.6 0.0 20.7 0.0 0.0 0.9 GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465342 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Early spermatids: 150.0;Late spermatids: 215.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045337 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "HPA045337: AB_10960528" "unprognostic (1.55e-1)" "unprognostic (3.00e-1)" "unprognostic (6.09e-3)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (8.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-5)" "unprognostic (1.33e-2)" "unprognostic (1.90e-1)" "unprognostic (2.71e-2)" "unprognostic (2.68e-3)" 1.2 1.7 1.3 0.6 1.1 0.2 0.9 3.3 1.5 2.2 3.5 1.5 0.2 2.0 1.1 0.6 3.1 0.8 2.1 0.9 1.7 0.9 0.6 0.9 0.3 1.5 1.5 2.5 0.9 2.5 3.4 0.6 0.8 1.9 0.5 0.8 0.6 2.7 0.8 0.6 0.9 1.2 0.8 0.5 1.0 6.0 1.3 0.2 1.4 0.3 0.3 2.1 1.5 1.2 0.4 0.5 0.8 1.0 0.7 1.0 0.7 0.9 0.5 0.6 0.6 0.2 0.9 0.4 0.6 1.1 0.2 0.5 0.4 0.3 0.8 0.9 0.3 0.3 2.8 0.3 0.6 0.5 0.4 0.6 0.6 0.9 0.4 1.3 0.4 0.4 0.5 0.6 0.8 0.3 0.1 1.2 0.6 0.0 1.8 0.6 0.6 0.4 0.6 0.4 1.1 1.3 2.1 0.3 0.1 0.4 0.4 0.2 1.5 1.5 1.2 0.4 1.0 0.1 0.0 0.3 0.5 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 1.1 3.3 1.5 0.9 1.7 1.5 1.5 0.8 0.8 1.3 1.2 1.0 0.0 0.5 9.1 1.1 0.3 0.8 0.4 0.0 5.0 0.5 0.4 2.6 1.5 2.7 3.7 2.1 0.4 0.3 0.0 0.0 0.6 150.0 9.7 4.5 0.7 3.0 0.8 21.3 0.7 0.3 2.4 0.5 0.5 0.0 7.0 1.1 0.2 0.1 1.7 20.6 0.2 0.0 0.0 0.5 215.5 3.1 0.6 0.0 3.7 0.4 4.3 1.0 7.5 13.3 0.5 0.0 3.8 0.4 1.1 0.4 1.1 7.6 2.4 0.0 3.6 2.8 22.7 1.8 0.2 0.1 0.1 0.5 5.4 0.7 0.2 GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 45.3;Extravillous trophoblasts: 243.2;Syncytiotrophoblasts: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Cell line enhanced" "Detected in many" "BEWO: 23.0;NB-4: 7.1" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" 47.9 2.6 16.9 2.0 17.2 9.0 41.8 17.0 20.9 10.0 22.1 14.1 2.8 13.2 2.8 4.7 12.3 7.5 13.2 13.6 15.4 5.3 20.4 24.9 4.1 18.6 18.4 7.4 5.9 1.6 3.4 10.2 18.7 7.2 1.0 3.6 9.6 5.5 10.7 11.2 8.1 3.5 16.6 6.7 12.9 2.6 21.8 1.7 11.5 8.8 1.2 13.2 8.7 17.3 1.2 1.0 0.4 1.0 1.3 0.3 23.0 0.1 0.9 0.2 1.1 0.8 1.1 0.4 0.7 0.1 3.5 0.8 0.0 0.3 0.1 0.8 0.9 1.7 0.7 1.9 1.5 0.1 0.2 0.5 0.0 0.7 0.0 2.4 1.7 0.6 1.1 1.2 0.2 0.7 0.0 7.1 1.6 1.3 0.6 5.5 0.0 1.5 0.3 0.1 1.2 1.7 1.8 0.2 2.0 0.9 1.1 2.2 0.5 1.0 1.1 1.6 0.8 1.9 2.1 0.1 6.1 2.2 2.1 0.0 0.2 95.2 0.6 0.1 1.2 0.0 8.4 0.7 1.7 0.1 25.6 4.8 0.1 1.3 0.3 14.3 14.5 4.3 16.9 17.2 17.0 20.9 13.6 15.4 18.6 18.4 18.7 16.6 21.8 17.3 96.3 0.0 2.8 7.2 3.3 1.8 0.8 1.8 1.2 3.7 7.6 3.4 0.3 1.5 2.1 1.8 0.0 9.3 1.4 0.3 1.9 1.0 0.1 3.2 0.4 45.3 4.2 30.5 0.9 0.6 243.2 4.8 2.0 3.7 2.5 1.7 16.4 21.3 10.9 3.3 1.4 0.3 2.0 0.6 6.1 1.1 3.1 1.7 3.6 3.7 0.2 21.2 2.1 4.5 1.7 0.7 0.3 3.4 0.9 0.7 0.8 3.4 0.0 5.7 0.0 2.3 1.4 0.5 1.5 0.4 2.3 82.4 2.5 0.9 1.0 0.4 GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 83.4;stomach 1: 52.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 125.1;Excitatory neurons: 99.4;Inhibitory neurons: 131.1;Melanocytes: 152.9;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 14.6;WM-115: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies, Cytosol" "HPA036159: AB_10671835, HPA057384: AB_2683424" "unprognostic (3.91e-2)" "unprognostic (7.93e-2)" "unprognostic (3.14e-2)" "unprognostic (4.11e-4)" "unprognostic (5.03e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (4.82e-2)" "unprognostic (2.59e-2)" "unprognostic (9.90e-2)" "unprognostic (1.82e-2)" "unprognostic (4.54e-2)" 4.3 9.7 8.7 5.9 16.3 2.3 2.4 6.5 12.1 2.4 83.4 10.2 3.8 1.9 12.3 5.9 1.6 5.7 7.0 12.2 5.3 20.1 7.3 3.0 6.3 5.5 5.3 2.5 18.2 8.9 2.3 4.4 5.2 7.5 3.7 10.0 3.6 8.4 4.7 13.2 4.0 6.1 3.5 5.4 52.6 2.2 7.1 3.0 8.3 4.4 3.6 4.1 2.7 6.1 0.7 0.3 0.8 2.0 4.9 2.7 0.5 3.8 1.3 0.6 2.1 0.3 0.2 2.2 1.2 2.8 1.3 0.2 1.3 1.1 2.1 0.8 1.5 2.3 1.1 0.2 0.9 0.7 1.1 3.9 3.1 1.9 0.6 4.0 1.0 3.0 0.3 5.5 4.2 0.6 1.6 0.8 0.4 2.3 1.5 1.9 5.6 1.0 2.0 1.3 5.9 5.0 1.2 0.8 2.0 2.5 0.3 0.3 2.6 2.7 1.0 3.9 0.5 14.6 2.2 0.3 3.0 0.6 9.9 1.3 2.2 0.1 1.8 4.0 1.6 1.1 3.1 2.9 0.6 1.0 2.5 3.9 7.3 3.6 5.7 0.3 5.5 1.4 8.7 16.3 6.5 12.1 12.2 5.3 5.5 5.3 5.2 3.5 7.1 6.1 18.5 12.8 3.6 31.3 9.8 42.7 4.0 4.0 29.0 34.9 5.8 6.1 26.0 2.8 6.8 11.0 125.1 1.5 12.2 0.6 1.9 1.9 0.7 1.4 24.1 9.8 12.7 15.2 99.4 6.0 1.2 9.7 9.7 0.6 1.3 4.0 16.1 16.1 6.1 50.5 131.1 0.8 2.0 50.4 23.0 1.8 14.9 27.0 152.9 8.4 34.3 16.7 11.3 130.2 21.2 3.5 0.1 32.0 14.3 3.1 0.4 41.7 0.5 25.8 0.0 16.9 9.5 3.3 3.2 7.5 28.6 0.8 25.7 52.4 1.0 1.8 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enriched" "Detected in many" 8 "Horizontal cells: 158.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Uncertain Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" 3.5 1.1 3.8 5.3 2.8 0.2 2.7 3.3 4.0 6.7 1.1 8.4 1.5 41.5 3.6 9.8 10.7 5.6 3.1 3.8 2.4 1.4 0.4 4.2 0.9 3.7 9.4 7.3 11.7 5.4 1.7 2.2 3.8 9.5 3.2 2.1 1.8 11.8 1.0 2.1 3.3 27.6 2.8 2.0 2.9 1.7 4.1 2.0 1.7 1.9 1.3 4.6 5.4 2.7 11.7 7.1 28.0 18.1 6.6 11.7 0.0 11.1 11.9 9.2 9.7 44.9 1.8 0.0 6.0 16.6 17.2 33.9 6.9 10.7 5.3 4.4 8.8 4.2 5.8 0.1 2.8 1.2 2.8 4.2 6.9 7.9 12.7 21.3 18.7 3.6 3.9 0.1 14.2 1.0 1.3 0.2 11.5 19.4 11.0 3.4 12.1 0.0 4.9 3.1 5.7 24.6 12.0 0.4 32.2 10.6 6.3 1.4 25.4 18.9 9.7 25.6 12.7 0.0 0.0 0.0 5.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.8 3.3 4.0 3.8 2.4 3.7 9.4 3.8 2.8 4.1 2.7 5.8 3.2 1.1 13.7 0.1 2.2 5.7 2.5 5.2 2.2 2.2 4.2 3.6 0.0 1.4 0.0 0.0 0.5 0.0 2.8 0.0 4.1 0.4 1.3 19.4 9.1 0.0 0.0 10.8 8.0 0.4 12.3 1.1 1.8 0.0 15.3 8.9 0.1 0.8 158.2 10.9 1.5 0.0 2.5 6.3 0.9 7.5 2.0 1.8 3.7 1.1 3.2 0.0 9.5 0.4 2.6 2.4 17.0 0.0 10.9 0.0 0.1 1.1 2.1 19.7 8.8 15.1 0.3 3.3 2.7 1.4 0.4 1.0 0.7 2.5 2.7 GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enriched" "Detected in some" 4 "T-cells: 107.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.3" "Lineage enriched" "Detected in many" 15 "T-cells: 110.3" "Cell line enriched" "Detected in some" 25 "U-266/70: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" 3.7 1.6 0.5 21.3 1.5 1.2 1.9 1.7 3.8 4.3 12.3 4.3 4.5 1.5 0.5 2.5 3.0 6.2 0.9 1.1 0.4 1.3 4.3 6.4 17.4 2.5 0.7 0.8 0.7 0.2 0.5 0.5 0.7 1.9 4.6 0.0 1.7 0.8 0.2 0.9 12.9 1.1 0.1 13.0 5.9 0.3 1.1 13.0 1.8 0.1 11.3 9.3 2.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.2 0.1 0.0 0.0 0.2 0.0 0.2 0.3 3.5 27.9 0.2 110.3 0.0 40.2 53.5 2.3 0.5 24.1 21.1 0.8 7.3 0.5 2.2 21.4 9.4 0.5 1.5 1.7 3.8 1.1 0.4 2.5 0.7 0.7 0.1 1.1 1.2 0.4 0.0 2.2 0.3 2.3 1.1 0.4 0.0 0.6 4.8 0.3 0.3 1.0 0.0 1.3 0.0 2.1 0.4 25.8 0.1 0.0 0.0 0.2 0.1 0.6 0.5 0.0 2.7 0.8 0.0 0.0 2.3 4.6 0.1 2.5 0.0 1.8 1.6 0.1 21.9 0.3 0.5 0.0 2.2 8.1 0.1 0.0 4.8 0.0 0.0 14.0 5.7 6.2 0.5 0.0 0.0 0.0 0.0 14.9 0.2 0.0 0.5 0.0 0.1 0.0 0.5 1.2 0.8 0.7 0.1 0.6 0.7 107.6 0.1 0.0 0.3 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Enteroendocrine cells: 1.8;Excitatory neurons: 2.3;Langerhans cells: 3.1;Plasma cells: 2.4;T-cells: 4.2" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "Karpas-707: 32.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" 0.2 0.0 0.3 1.8 4.6 0.2 0.5 0.0 0.5 0.1 0.0 0.8 1.3 0.1 0.0 0.5 0.1 0.5 0.1 0.3 0.4 0.0 0.2 0.5 2.9 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 1.0 0.2 0.0 0.4 2.2 0.1 0.0 4.1 0.7 4.7 1.0 1.9 0.1 0.0 4.4 0.9 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.0 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.8 32.0 0.0 0.0 0.2 0.9 0.7 0.0 1.0 0.1 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 6.0 0.0 0.0 2.3 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 1.9 0.1 0.9 0.2 0.9 0.1 0.7 1.3 1.7 0.3 4.6 0.0 0.5 0.3 0.4 0.1 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.3 2.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.0 2.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.1 1.4 0.0 0.3 3.1 0.9 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.5 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.2 0.1 0.2 0.1 GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Cone photoreceptor cells: 20.9;Kupffer cells: 37.0;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Cell line enriched" "Detected in single" 30 "HMC-1: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" 0.1 0.9 0.7 2.3 0.5 0.1 0.6 0.8 0.7 0.3 0.4 1.1 1.7 0.3 0.1 0.4 0.3 0.6 0.1 0.5 1.0 0.3 0.7 0.2 3.2 1.4 0.7 0.2 0.1 0.2 0.1 0.0 0.7 0.2 1.1 0.0 0.4 0.4 0.0 0.4 2.7 0.3 0.6 1.1 0.9 0.0 1.3 0.5 0.3 0.0 6.9 0.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 40.2 0.0 2.5 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.3 10.9 2.4 0.0 0.0 0.2 0.7 0.5 0.8 0.7 0.5 1.0 1.4 0.7 0.7 0.6 1.3 0.8 0.7 0.0 7.2 2.0 5.5 4.7 5.2 2.8 0.6 16.5 1.2 0.3 0.4 4.3 5.9 1.8 20.9 0.9 3.7 3.1 0.0 2.0 0.2 1.0 3.4 3.1 1.2 0.8 1.7 1.1 0.2 2.9 1.5 1.4 0.0 1.4 3.3 1.3 1.3 13.5 2.2 2.0 2.0 37.0 7.7 0.2 4.1 13.9 3.6 0.0 3.4 1.7 12.3 10.6 1.1 2.8 5.1 3.0 1.3 3.6 6.9 0.3 1.1 17.2 0.0 3.4 2.3 1.6 1.1 0.3 2.7 0.7 12.6 3.9 3.4 3.8 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 78.7;Macrophages: 53.9;Sertoli cells: 78.9;T-cells: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 102.6;RPMI-8226: 27.7;SCLC-21H: 27.2;U-266/70: 15.9;U-266/84: 13.2" "Region enhanced" "Detected in many" "basal ganglia: 16.2" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA043148: AB_2678341, HPA057666: AB_2683496, HPA059092: AB_2683902" "unprognostic (9.05e-2)" "unprognostic (4.92e-2)" "prognostic favorable (7.22e-5)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-3)" "unprognostic (3.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.34e-3)" "unprognostic (3.13e-1)" "prognostic favorable (8.33e-4)" "unprognostic (1.91e-1)" "unprognostic (5.35e-2)" "unprognostic (3.93e-1)" "unprognostic (7.82e-4)" 2.7 1.2 4.1 9.0 9.5 7.8 1.4 17.8 3.1 2.2 0.9 5.3 6.2 1.4 0.7 0.9 0.9 3.5 4.0 2.2 7.3 3.9 2.0 6.9 10.2 4.3 6.5 3.2 5.1 0.6 2.9 1.0 4.5 0.8 7.1 3.5 1.5 0.6 1.0 0.6 5.3 1.4 4.1 7.1 3.6 0.4 5.0 2.8 1.3 3.2 7.9 2.7 1.0 5.9 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.8 0.1 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 102.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 27.7 0.3 0.1 27.2 0.6 0.0 0.1 1.1 1.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 15.9 13.2 0.1 0.5 0.0 0.0 0.0 0.3 0.0 2.8 1.0 3.8 0.2 2.7 2.2 0.9 0.0 1.1 1.1 0.0 1.9 1.5 0.0 3.4 1.0 4.1 9.5 17.8 3.1 2.2 7.3 4.3 6.5 4.5 4.1 5.0 5.9 11.1 0.0 22.6 10.1 6.7 1.1 0.9 0.1 0.0 12.2 1.6 1.7 20.3 8.6 5.0 3.7 0.0 0.2 51.2 17.4 1.9 2.0 0.2 5.8 3.4 11.7 78.7 6.5 21.7 9.4 0.1 3.0 15.8 15.0 7.6 12.2 1.8 0.4 18.7 26.9 32.7 38.0 0.0 28.2 29.0 0.0 0.3 53.9 1.8 41.2 7.4 1.0 23.7 26.2 0.5 1.3 11.0 1.2 48.6 0.3 16.3 1.9 0.7 10.8 78.9 3.3 32.7 0.1 0.8 0.3 1.0 0.3 76.9 0.7 26.2 0.5 GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 160.8;lymphoid tissue: 229.3" "Cell type enhanced" "Detected in many" "B-cells: 261.0;dendritic cells: 238.9;Hofbauer cells: 278.3;Kupffer cells: 397.2;Langerhans cells: 209.3;Macrophages: 268.2;monocytes: 375.1;NK-cells: 352.2;T-cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 226.9;NB-4: 115.8;THP-1: 107.1;U-937: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 73000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.93e-2)" "unprognostic (2.51e-2)" "unprognostic (2.02e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.66e-1)" "unprognostic (6.61e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (6.92e-9)" "unprognostic (2.01e-2)" "unprognostic (1.69e-2)" "unprognostic (5.47e-2)" "unprognostic (5.87e-2)" 28.7 11.8 11.1 96.8 10.3 160.8 15.5 10.8 14.1 8.9 10.5 17.9 14.4 6.8 9.1 9.4 13.9 24.8 14.9 10.5 13.4 15.9 14.5 62.9 139.9 15.6 13.6 5.3 6.1 1.8 7.6 22.2 13.9 13.8 15.8 0.3 11.8 5.5 3.7 9.1 67.7 10.0 12.3 229.3 17.5 5.6 14.6 83.0 11.6 5.6 100.8 32.8 9.1 14.4 1.0 0.0 1.6 0.6 0.1 0.2 1.5 1.3 17.0 5.6 8.8 0.2 5.2 41.1 7.8 6.7 0.5 0.9 0.1 7.2 3.1 53.8 0.1 59.5 0.0 1.2 9.6 0.0 226.9 2.0 0.0 1.9 5.9 1.2 25.8 25.7 11.4 47.9 1.6 0.0 23.6 115.8 0.0 0.0 0.5 24.5 0.0 38.4 1.4 0.0 0.6 0.1 0.0 0.6 8.7 2.1 1.1 107.1 22.6 3.0 3.1 0.0 1.5 1.1 0.9 25.9 0.9 76.3 15.5 44.1 55.8 194.3 35.5 73.3 35.7 52.8 45.5 44.7 57.9 41.9 38.5 42.7 244.9 27.1 71.5 24.3 34.7 53.2 11.1 10.3 10.8 14.1 10.5 13.4 15.6 13.6 13.9 12.3 14.6 14.4 12.8 0.0 2.2 1.0 261.0 11.2 12.9 11.5 4.0 0.2 7.7 9.1 0.5 2.8 7.3 3.7 0.0 3.4 238.9 2.2 0.0 7.9 6.5 1.1 1.0 19.5 1.2 46.3 0.1 5.2 5.1 7.1 8.6 0.9 57.8 0.5 28.2 4.4 278.3 0.0 0.3 6.5 30.5 397.2 209.3 12.1 1.2 268.2 44.4 4.7 375.1 0.5 352.2 0.0 0.3 20.5 34.2 0.0 76.4 5.8 0.5 2.4 5.5 0.5 6.6 1.3 9.4 0.8 3.9 1.4 8.5 6.3 256.1 7.8 3.7 24.6 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 386.1;Distal enterocytes: 436.6;Gastric mucus-secreting cells: 912.3;Hepatocytes: 753.4;Intestinal goblet cells: 438.6;Paneth cells: 463.0;Undifferentiated cells: 776.8;Urothelial cells: 1062.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 4748.8" "Region enhanced" "Detected in single" "pons and medulla: 1.2" "Low region specificity" "Detected in some" HPA003545 Enhanced Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" 1.9 0.2 0.1 53.8 0.3 0.3 5.3 0.5 0.3 23.5 0.1 333.5 96.7 0.7 1.7 187.7 4.9 497.7 0.3 0.2 0.5 30.6 634.0 2.6 0.1 0.4 0.2 0.2 24.5 0.0 1.2 0.2 0.4 43.3 453.8 0.0 71.8 24.9 0.3 25.4 175.7 9.7 0.1 0.6 374.6 2.5 0.3 3.3 0.5 0.0 1.2 350.5 108.2 0.7 0.0 1152.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 36.9 9.6 0.0 6.0 0.0 1.9 303.7 0.6 4.8 0.0 0.2 0.1 0.1 1.1 1048.6 0.0 0.1 0.4 0.0 9.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 5.6 0.6 0.3 1.3 4748.8 0.2 0.5 0.2 0.2 0.1 727.5 324.2 0.2 0.1 13.4 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.2 0.5 0.4 0.2 0.4 0.1 0.3 0.7 0.1 0.0 0.0 0.3 6.9 9.9 169.4 104.5 42.1 0.2 0.6 4.1 0.4 386.1 17.1 23.9 0.0 0.1 0.0 436.6 11.7 272.8 13.8 3.8 0.5 3.5 115.2 50.8 0.2 260.6 0.1 2.1 912.3 2.8 13.4 0.1 17.5 753.4 0.0 0.0 0.2 438.6 36.7 26.1 0.8 66.6 0.9 3.5 0.0 1.9 3.2 0.0 0.0 0.0 0.4 163.7 463.0 0.0 2.4 100.7 68.1 31.4 9.0 0.7 0.0 0.0 3.6 0.4 0.0 315.5 9.7 0.0 5.9 0.1 776.8 1062.0 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.9;placenta: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 70.5;Cytotrophoblasts: 106.2;Extravillous trophoblasts: 29.5;Syncytiotrophoblasts: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 165.5;SK-BR-3: 75.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" 0.0 0.0 2.1 0.5 1.7 0.0 10.2 2.0 1.3 1.9 2.1 1.2 1.0 0.4 35.9 1.1 5.8 0.3 0.1 2.2 3.9 3.2 0.0 15.0 0.4 6.5 13.1 0.1 0.5 0.1 0.7 48.7 10.1 1.3 0.8 0.9 2.1 5.2 0.0 2.5 3.3 0.2 2.6 0.2 0.8 0.4 3.0 0.2 8.9 0.0 0.4 0.3 0.7 2.0 2.1 0.0 0.1 0.0 0.0 0.0 165.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.0 0.0 1.2 0.0 10.0 0.2 0.0 0.2 0.3 0.1 0.0 1.2 0.0 0.0 0.1 2.1 0.0 7.5 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.2 0.1 1.7 0.1 0.3 75.8 0.1 5.5 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 2.0 1.3 2.2 3.9 6.5 13.1 10.1 2.6 3.0 2.0 0.1 70.5 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.3 0.0 0.0 7.4 3.7 0.0 106.2 0.1 0.0 0.0 0.1 0.0 14.0 0.2 0.2 0.0 0.0 0.0 0.0 29.5 0.8 0.0 0.7 1.3 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 10.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 147.1 0.3 0.1 0.0 0.0 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 GRIN1 "GluN1, NMDAR1" ENSG00000176884 "Glutamate ionotropic receptor NMDA type subunit 1" Q05586 9 137139154-137168756 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 186.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 132.6;Inhibitory neurons: 134.4" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.8" "Region enriched" "Detected in many" 4 "cerebral cortex: 186.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.4;REH: 1.9;RPMI-8226: 2.5;SCLC-21H: 5.2;SH-SY5Y: 3.1;T-47d: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067773 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA067773: " "unprognostic (3.58e-2)" "unprognostic (4.51e-1)" "unprognostic (2.68e-2)" "unprognostic (5.48e-4)" "unprognostic (5.20e-2)" "unprognostic (1.25e-1)" "unprognostic (2.34e-2)" "unprognostic (2.81e-2)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (4.47e-2)" "unprognostic (1.44e-1)" "unprognostic (3.56e-3)" "unprognostic (4.72e-2)" 0.0 0.1 15.7 0.2 46.4 0.0 0.2 0.0 186.7 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 35.9 0.0 0.0 0.0 0.1 0.1 1.3 19.5 0.0 0.1 0.2 0.7 0.0 3.8 0.7 0.0 3.7 1.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.4 0.0 1.9 0.0 2.5 0.0 0.0 5.2 3.1 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 46.4 0.0 186.7 35.9 0.0 1.3 19.5 3.8 0.0 0.0 35.6 0.0 0.0 0.0 8.5 0.0 0.0 0.3 0.1 0.0 28.0 1.2 0.9 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 1.9 0.2 0.1 0.2 1.8 0.0 132.6 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.7 134.4 1.8 0.0 0.0 0.0 0.6 0.0 0.2 0.0 9.4 2.0 1.7 0.0 10.1 7.6 0.2 0.1 0.0 0.0 0.7 0.5 0.1 0.3 7.8 0.0 0.0 0.1 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 263.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 373.2;Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 182.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 340000 "Cluster 18: Basophils - Vesicular transport" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 13.9 34.7 11.1 9.7 12.5 9.3 23.2 13.2 16.3 12.7 10.5 21.9 22.5 10.8 22.1 26.9 14.9 11.9 14.3 10.5 12.3 24.5 263.1 7.8 13.5 12.6 11.7 6.5 20.1 26.4 13.3 11.2 12.8 21.1 21.7 5.1 24.1 9.6 47.4 22.1 15.6 7.9 12.3 12.1 18.9 57.8 11.9 14.0 19.5 37.3 17.4 11.9 13.8 14.0 18.8 39.0 27.6 19.9 17.1 23.9 45.8 11.4 11.9 21.6 30.9 13.0 45.2 43.5 14.9 13.6 13.4 24.1 18.9 22.5 20.7 23.2 21.0 20.8 13.3 26.9 26.3 7.8 15.8 22.1 24.0 12.4 20.8 12.0 18.6 24.7 17.5 37.0 14.5 182.1 12.2 16.4 8.2 64.1 30.3 20.2 29.5 34.2 32.5 24.0 30.2 26.2 26.0 49.1 35.6 15.5 81.2 11.1 13.8 17.0 52.5 18.9 8.6 28.2 32.7 35.2 41.9 11.3 20.8 13.4 15.5 9.9 2.6 22.2 2.4 8.2 4.6 3.7 20.7 10.4 3.9 3.1 1.6 5.1 20.1 15.0 7.9 7.4 11.1 12.5 13.2 16.3 10.5 12.3 12.6 11.7 12.8 12.3 11.9 14.0 6.1 6.4 9.6 6.5 13.5 13.4 19.8 26.2 15.9 7.3 36.1 34.2 13.0 47.1 19.0 9.2 4.2 91.4 7.5 34.9 46.9 45.0 125.8 19.4 15.6 11.1 28.8 30.3 2.9 68.0 62.5 15.0 33.1 27.0 3.8 25.7 15.4 373.2 44.6 16.8 3.3 45.7 20.3 38.1 10.9 398.1 11.8 19.0 17.8 3.7 30.4 26.4 4.1 2.0 9.2 41.8 37.4 6.0 13.2 19.8 72.9 77.8 15.0 11.9 0.0 12.3 13.2 51.3 29.4 38.0 14.1 76.2 6.7 55.8 50.3 30.3 GTF3C1 TFIIIC220 ENSG00000077235 "General transcription factor IIIC subunit 1" Q12789 16 27459555-27549913 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 93.8;dendritic cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051617, HPA075900" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA051617: AB_2681553, HPA075900: " "unprognostic (6.46e-2)" "unprognostic (6.86e-3)" "unprognostic (2.16e-1)" "unprognostic (5.59e-2)" "unprognostic (6.65e-2)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (8.23e-2)" "unprognostic (9.25e-3)" "unprognostic (5.32e-2)" "prognostic favorable (9.56e-4)" "unprognostic (2.10e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.06e-1)" "unprognostic (5.67e-2)" "unprognostic (5.56e-3)" "unprognostic (8.23e-3)" 18.1 28.8 24.2 9.9 24.4 16.6 16.7 21.5 32.6 31.2 40.5 21.2 8.8 26.7 7.8 65.2 24.6 11.5 38.5 24.6 21.8 25.4 21.7 20.3 12.2 20.4 20.8 24.4 35.3 18.6 47.8 11.0 19.6 40.4 9.7 18.3 24.9 12.6 50.2 51.0 18.5 15.5 17.0 21.3 24.7 26.6 22.2 18.6 34.6 20.8 11.2 19.7 35.1 21.7 27.8 60.1 43.3 50.7 37.8 30.4 24.6 29.5 33.0 40.2 34.0 45.0 25.6 30.5 42.3 36.4 30.6 30.3 55.4 37.6 32.9 13.7 53.1 25.2 49.8 63.8 21.3 29.1 32.2 37.5 28.0 49.5 21.8 26.9 40.2 34.6 31.7 24.2 32.0 67.6 32.5 34.8 58.4 15.1 28.3 59.7 53.4 31.4 25.2 28.7 54.4 36.5 29.8 24.9 18.6 34.4 44.8 21.8 43.2 40.2 24.0 25.6 30.7 25.6 24.8 30.2 16.6 31.7 30.2 2.6 3.4 3.5 31.9 3.2 23.0 3.1 3.6 15.8 4.3 2.2 3.7 10.0 2.5 12.2 3.3 6.6 4.0 6.9 24.2 24.4 21.5 32.6 24.6 21.8 20.4 20.8 19.6 17.0 22.2 21.7 16.9 19.2 23.9 29.7 10.8 18.4 7.3 14.3 23.3 45.5 10.6 11.9 27.4 10.0 17.2 12.9 93.8 7.8 86.2 18.4 5.9 11.8 2.8 40.4 37.3 18.0 30.0 7.2 30.2 11.5 4.3 22.5 19.9 22.3 19.0 26.1 13.9 13.7 10.9 26.9 33.9 17.6 18.3 10.3 7.7 4.5 19.3 12.9 3.6 14.0 10.0 15.0 52.5 17.1 23.4 15.8 9.3 15.8 29.6 13.9 10.2 9.0 30.8 35.1 13.1 16.4 15.1 17.2 18.2 34.8 20.6 4.2 32.7 25.7 12.2 6.7 GUCY2D "CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1" ENSG00000132518 "Guanylate cyclase 2D, retinal" Q02846 17 8002615-8020342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 34.2" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 58.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 31 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in single" 50 "dendritic cells: 8.0" "Cell line enriched" "Detected in some" 5 "JURKAT: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 79: Retina - Phototransduction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.57e-4)" "unprognostic (5.05e-1)" "unprognostic (1.49e-1)" "unprognostic (9.75e-5)" "unprognostic (5.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.44e-2)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" "unprognostic (4.44e-1)" "unprognostic (7.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.46e-1)" "unprognostic (3.08e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.4 1.3 5.2 5.7 2.1 1.4 3.8 1.9 0.0 1.4 0.0 62.6 1.2 2.7 0.0 1.9 0.1 6.9 0.2 0.1 0.1 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.6 0.0 0.1 0.0 1.2 1.1 0.0 0.4 0.0 0.0 0.6 0.0 14.9 0.0 0.6 0.0 0.0 0.8 6.1 0.0 0.0 0.1 0.1 0.0 0.4 0.0 1.1 0.0 0.4 0.1 58.3 0.0 0.0 0.0 0.4 0.1 2.4 0.3 2.2 0.1 0.0 0.2 0.5 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991408-149031775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 560.0;tongue: 357.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 229.8;Early spermatids: 251.2;Late spermatids: 368.8;Spermatocytes: 296.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030497, HPA073229" Supported Approved Vesicles NA NA 30000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030497: AB_10602326, HPA073229: " "unprognostic (2.68e-2)" "unprognostic (6.31e-3)" "unprognostic (3.21e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (7.75e-3)" "unprognostic (1.29e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" 40.3 31.1 30.1 31.3 32.2 219.8 33.8 33.1 39.4 36.5 28.7 152.2 16.7 64.1 38.7 53.6 52.6 23.9 117.8 29.9 44.0 29.0 18.6 41.1 24.8 37.0 39.7 43.8 42.7 25.2 31.5 23.0 39.0 47.3 25.6 34.3 39.7 64.4 560.0 21.2 37.7 68.1 35.9 59.2 50.7 115.1 33.6 18.0 21.1 357.6 23.0 86.1 30.8 38.3 62.7 39.8 29.0 32.6 78.5 81.7 39.5 90.2 74.4 128.3 119.2 52.3 62.2 0.1 43.5 105.1 68.4 18.8 76.7 39.8 128.6 21.1 33.3 47.6 16.7 59.9 70.7 49.1 68.8 45.1 63.8 42.7 53.3 66.8 74.7 30.7 29.8 109.8 74.7 110.3 9.6 38.9 34.9 48.3 32.2 26.7 43.8 89.3 35.7 57.6 23.7 11.3 47.6 64.6 54.4 27.3 64.4 51.4 62.9 65.4 19.4 47.4 66.9 98.7 59.1 44.4 55.1 74.3 21.7 22.7 58.1 42.4 39.4 59.6 73.1 15.9 25.7 41.3 64.0 14.0 13.8 23.5 27.0 44.3 67.9 25.3 39.4 50.1 30.1 32.2 33.1 39.4 29.9 44.0 37.0 39.7 39.0 35.9 33.6 38.3 27.7 12.8 11.1 16.3 28.3 12.1 22.4 27.7 12.5 9.4 22.5 17.1 229.8 15.7 21.9 33.1 18.8 36.5 50.4 9.9 27.4 43.4 251.2 7.9 15.2 32.6 14.4 12.2 9.8 77.6 47.2 45.0 17.3 9.5 18.3 19.7 45.3 13.5 95.3 6.7 11.3 19.0 26.4 87.1 26.3 368.8 53.1 56.2 40.9 6.5 56.2 132.1 36.0 11.6 5.4 31.6 14.3 76.8 104.1 45.9 15.0 17.3 16.1 7.0 65.7 35.8 50.3 296.7 52.2 23.1 14.9 29.3 61.2 33.8 15.2 19.6 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in many" 10 "dendritic cells: 575.2;NK-cells: 492.3;T-cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.4 5.2 1.2 3.1 1.3 33.9 4.6 1.3 2.4 2.6 1.6 2.7 2.4 2.0 5.0 3.6 3.5 7.0 2.5 1.1 1.3 1.2 6.7 15.9 25.2 2.0 1.2 2.8 0.8 0.7 2.4 1.6 1.5 1.4 2.5 0.0 7.9 2.1 1.9 0.6 2.8 3.4 1.3 24.4 4.7 0.8 1.4 3.8 1.5 0.6 4.5 7.5 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 31.6 3.4 1.7 1678.5 3.6 30.2 7.6 490.7 1389.6 3.3 4.6 155.1 1214.0 18.6 250.8 5.4 44.6 4.5 1436.5 1.2 1.3 1.3 2.4 1.1 1.3 2.0 1.2 1.5 1.3 1.4 1.3 2.9 0.0 4.6 0.0 3.3 1.1 0.1 0.0 0.0 0.0 1.7 1.5 1.4 8.6 0.0 0.0 0.0 0.1 575.2 0.0 0.0 0.1 0.1 0.3 0.3 1.5 0.0 8.6 0.0 0.0 0.0 1.2 1.1 0.4 1.3 0.0 7.5 1.2 0.1 0.0 0.0 0.0 0.0 9.3 3.4 0.2 0.0 4.5 3.6 1.9 3.1 0.0 492.3 0.0 0.1 0.0 0.0 0.0 43.7 0.2 0.0 2.6 0.7 0.0 0.0 1.9 1.3 0.1 0.0 0.4 1.8 0.0 302.2 0.0 0.1 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 49.3;Cytotrophoblasts: 42.7;Extravillous trophoblasts: 68.1;Hofbauer cells: 75.5;Syncytiotrophoblasts: 298.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 258.6;eosinophil: 458.7;neutrophil: 229.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 458.7" "Cell line enhanced" "Detected in many" "K-562: 334.2;SiHa: 311.1;U-2 OS: 601.6;U-266/70: 673.7;U-266/84: 661.8" "Low region specificity" "Detected in all" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 5500000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli rim" "CAB011507: AB_2117984, HPA055907: AB_2682966" "unprognostic (4.43e-2)" "unprognostic (1.57e-3)" "unprognostic (1.31e-2)" "unprognostic (2.96e-2)" "unprognostic (5.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.85e-1)" "unprognostic (8.93e-2)" "unprognostic (3.08e-1)" "prognostic favorable (8.06e-5)" 72.2 47.6 67.1 27.2 55.3 229.5 71.7 148.8 64.2 116.1 84.5 54.5 33.6 14.6 42.0 70.3 41.3 18.9 154.7 51.1 60.1 236.3 130.0 60.5 31.5 64.6 70.4 89.4 60.5 8.7 15.2 43.8 56.7 132.9 44.2 22.0 39.8 16.4 227.4 65.0 42.8 7.9 57.4 56.6 73.4 26.8 71.4 62.0 59.7 99.1 27.8 29.5 90.6 76.7 39.9 27.5 20.5 21.9 49.9 10.0 0.7 19.5 30.8 87.9 92.6 14.9 28.1 3.1 109.6 25.6 32.8 17.3 6.4 15.0 24.3 38.7 23.4 16.5 27.8 17.5 14.7 7.8 38.4 70.4 19.9 11.5 19.2 27.3 13.8 17.6 334.2 243.3 43.7 17.3 20.8 18.3 11.5 96.3 41.4 10.8 9.5 129.1 52.8 28.1 52.6 17.9 311.1 53.0 22.0 19.1 65.8 12.5 6.8 41.1 601.6 12.5 9.0 673.7 661.8 31.3 29.9 253.6 14.4 258.6 14.3 458.7 19.3 14.2 24.4 57.7 31.9 21.4 30.5 76.8 29.4 23.1 229.3 20.2 18.9 31.6 48.3 22.1 67.1 55.3 148.8 64.2 51.1 60.1 64.6 70.4 56.7 57.4 71.4 76.7 14.9 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 0.0 0.0 42.7 29.2 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 68.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 75.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 298.4 4.5 0.0 0.0 0.0 H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774383-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 565.0" "Cell type enhanced" "Detected in some" "Adipocytes: 58.1;Cytotrophoblasts: 130.2;dendritic cells: 56.4;Extravillous trophoblasts: 124.3;Fibroblasts: 59.5;Hofbauer cells: 241.2;Syncytiotrophoblasts: 160.3" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 256.2;MCF7: 338.4;RT4: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" 236.7 186.0 29.1 33.8 34.1 60.4 223.6 33.7 40.9 123.7 37.9 126.6 55.4 105.6 20.9 155.7 106.6 36.0 125.5 27.7 31.3 115.7 82.7 129.6 29.6 37.1 32.5 63.6 182.3 21.1 34.2 57.7 35.7 275.8 29.3 5.3 166.8 35.0 91.4 198.4 85.2 25.1 33.4 94.8 111.1 565.0 33.1 34.2 85.0 24.8 18.2 122.8 124.9 38.7 107.9 256.2 10.0 0.0 112.2 73.8 163.2 78.9 43.4 31.3 30.4 50.9 172.4 0.1 48.7 38.6 0.2 100.7 6.2 60.1 8.5 5.7 4.6 4.3 92.6 43.8 160.5 0.1 39.0 97.0 64.5 43.3 40.0 12.7 63.0 0.0 0.1 0.1 15.9 338.4 0.7 28.7 16.0 77.8 58.0 42.4 0.0 21.0 51.0 239.0 3.0 1.0 99.8 122.3 0.4 34.6 187.0 32.6 63.1 0.3 29.6 46.2 15.6 25.0 39.4 0.4 8.6 0.3 25.4 84.0 127.6 29.3 51.3 76.4 46.3 16.8 49.6 38.0 117.2 21.7 34.9 38.2 46.6 61.2 69.4 58.2 78.1 72.1 29.1 34.1 33.7 40.9 27.7 31.3 37.1 32.5 35.7 33.4 33.1 38.7 58.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 130.2 56.4 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 124.3 59.5 0.0 0.0 0.0 0.0 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 160.3 6.5 0.0 0.0 0.0 H2BC12 "H2BFAiii, H2BFT, HIST1H2BK" ENSG00000197903 "H2B clustered histone 12" O60814 6 27146361-27146855 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.4;Hofbauer cells: 1.1;Syncytiotrophoblasts: 3.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 1269.7;SiHa: 771.0;U-2 OS: 949.9;U-266/84: 1355.8" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.78e-2)" "unprognostic (4.70e-3)" "unprognostic (9.00e-3)" "unprognostic (1.30e-1)" "unprognostic (3.81e-1)" "unprognostic (4.50e-2)" "unprognostic (6.50e-2)" "unprognostic (4.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-3)" "unprognostic (3.46e-3)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (3.93e-2)" "unprognostic (1.49e-1)" "unprognostic (7.59e-2)" "unprognostic (2.37e-2)" 45.2 28.9 10.3 35.9 13.4 46.4 31.2 8.1 13.1 46.1 15.1 45.7 41.6 35.2 27.7 64.2 59.9 37.7 32.1 12.2 11.1 31.3 94.0 47.1 59.6 13.3 12.3 28.9 60.0 14.8 16.2 44.7 12.9 75.1 26.4 0.4 43.1 21.7 8.5 30.3 44.8 22.1 15.7 66.9 56.0 44.6 13.6 65.7 49.2 6.7 24.2 35.0 42.8 21.6 64.6 153.7 25.7 41.2 116.0 37.0 84.7 118.1 70.5 157.9 99.1 133.1 68.9 28.1 338.6 64.2 94.1 78.3 29.8 35.8 19.7 95.1 201.2 42.0 91.0 4.4 46.2 29.9 183.4 205.0 26.8 29.5 28.1 38.8 27.6 14.1 1269.7 194.4 66.5 166.3 49.1 52.6 20.2 204.6 98.8 27.9 24.2 265.9 55.2 23.4 124.1 74.2 771.0 178.6 56.9 18.9 473.7 29.8 41.6 57.6 949.9 54.0 18.8 293.6 1355.8 207.7 34.7 314.1 34.5 244.6 49.0 329.3 21.6 45.3 19.6 112.1 21.3 21.9 53.1 141.9 25.7 20.4 308.2 28.5 96.3 120.8 65.7 68.3 10.3 13.4 8.1 13.1 12.2 11.1 13.3 12.3 12.9 15.7 13.6 21.6 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 H2BC9 "H2B/j, H2BFJ, HIST1H2BH" ENSG00000275713 "H2B clustered histone 9" Q93079 6 26251651-26253710 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.2;vagina: 4.3" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.7;neutrophil: 3.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "U-266/70: 16.9" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (5.83e-2)" "unprognostic (6.27e-3)" "unprognostic (4.50e-2)" "unprognostic (9.18e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.06e-3)" "unprognostic (3.08e-3)" "unprognostic (1.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.86e-1)" "unprognostic (3.22e-1)" "unprognostic (2.96e-8)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-3)" 0.5 0.2 0.4 0.6 0.4 1.4 0.6 0.3 0.5 1.9 0.8 2.0 3.0 0.4 0.8 4.2 0.8 0.3 0.2 0.3 0.4 0.9 0.2 1.6 0.8 0.8 0.7 0.1 0.0 0.1 0.1 0.2 0.7 3.5 0.8 0.0 1.3 0.0 0.0 0.6 1.7 0.1 0.6 3.7 0.7 0.6 0.7 2.9 1.0 0.1 0.5 0.4 4.3 1.1 1.8 0.1 7.0 0.0 0.0 0.1 1.1 0.9 0.3 1.2 0.6 2.4 1.1 0.0 1.7 0.1 1.8 3.4 0.0 0.6 1.7 0.9 0.1 1.3 6.1 0.4 0.0 0.0 4.0 0.3 0.3 0.4 0.5 0.0 0.3 1.0 2.7 6.2 0.1 2.0 3.8 2.7 1.6 0.0 1.8 4.0 0.0 0.9 0.0 2.7 3.2 2.9 4.2 1.4 0.6 0.3 2.0 3.3 0.0 0.6 0.0 0.7 3.1 16.9 4.5 0.0 0.5 1.5 3.8 3.7 0.2 0.6 0.3 0.0 0.1 0.6 0.2 0.4 0.6 0.3 0.0 0.1 3.0 0.8 0.1 0.2 0.4 5.2 0.4 0.4 0.3 0.5 0.3 0.4 0.8 0.7 0.7 0.6 0.7 1.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 29.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 H3C6 "H3.1, H3/d, H3FD, HIST1H3E" ENSG00000274750 "H3 clustered histone 6" P68431 6 26224199-26227473 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.0;Syncytiotrophoblasts: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 10.5;hTERT-RPE1: 7.5;SCLC-21H: 11.9;T-47d: 7.3" "Low region specificity" "Detected in all" HPA042570 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA042570: AB_2678056" "unprognostic (2.42e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-3)" "unprognostic (9.07e-2)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (3.90e-1)" "unprognostic (1.83e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (7.66e-2)" 0.6 3.5 1.0 1.0 1.5 0.4 1.8 3.9 3.2 1.2 2.7 2.9 4.7 0.8 4.9 2.8 1.5 1.0 6.0 1.1 1.5 1.6 2.9 0.5 1.3 2.0 1.7 1.0 0.7 1.5 0.6 0.9 2.4 3.4 1.9 0.2 1.9 0.7 5.1 1.2 4.7 0.4 1.9 2.2 2.6 1.4 1.4 1.2 2.6 3.7 0.9 1.2 1.2 3.4 1.9 2.0 2.8 1.3 3.3 1.6 0.2 1.3 1.5 0.7 0.5 0.6 1.1 0.0 10.5 0.5 1.0 2.3 0.0 0.3 0.6 2.9 2.5 0.4 1.0 0.6 1.0 0.1 1.7 2.3 2.4 0.3 0.7 7.5 1.1 0.2 0.3 2.2 1.9 1.8 0.4 0.1 0.2 1.4 1.9 1.4 0.6 0.3 5.7 1.1 11.9 1.4 1.9 3.0 3.4 0.4 7.3 1.2 0.6 1.3 0.4 0.4 0.3 0.8 0.3 0.2 0.6 0.1 0.7 0.2 0.7 0.0 0.5 0.6 0.7 0.5 0.7 0.7 0.5 0.9 0.6 0.7 2.7 0.2 0.6 1.7 1.3 0.5 1.0 1.5 3.9 3.2 1.1 1.5 2.0 1.7 2.4 1.9 1.4 3.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 H4C8 "H4/h, H4FH, HIST1H4H" ENSG00000158406 "H4 clustered histone 8" P62805 6 26277609-26285638 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "brain: 51.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.8;dendritic cells: 3.4;Extravillous trophoblasts: 1.5;Hofbauer cells: 1.8;Plasma cells: 1.3;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 51.4" "Group enriched" "Detected in some" 7 "eosinophil: 4.2;neutrophil: 8.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.9" "Cell line enhanced" "Detected in many" "MOLT-4: 17.5;U-266/84: 29.8" "Low region specificity" "Detected in single" HPA042201 Supported NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (4.39e-1)" "unprognostic (1.62e-1)" "unprognostic (3.08e-3)" "unprognostic (5.00e-2)" "unprognostic (3.01e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (6.84e-4)" "unprognostic (5.40e-2)" "unprognostic (1.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (7.44e-2)" "unprognostic (8.16e-2)" "unprognostic (6.55e-2)" "unprognostic (6.36e-2)" 0.5 0.2 5.7 0.1 5.2 0.9 0.3 51.4 8.6 1.3 1.9 0.9 0.6 0.2 0.0 1.2 0.2 0.7 0.6 4.5 7.3 0.2 0.6 0.5 0.0 5.3 4.9 0.4 0.3 0.0 0.1 0.2 4.6 0.4 0.0 0.0 0.3 0.0 2.5 0.8 0.2 0.0 9.5 0.1 0.2 0.4 5.5 1.1 0.3 0.0 0.7 0.2 0.6 18.4 3.1 3.6 0.4 0.4 1.0 0.0 2.4 4.7 0.0 0.0 0.0 3.5 0.9 2.1 5.8 0.3 0.1 1.9 0.0 0.7 0.3 3.6 1.5 3.8 8.3 4.2 2.2 1.4 2.7 2.7 0.0 1.7 1.5 0.0 3.5 0.9 4.2 0.0 1.9 3.5 17.5 10.9 1.6 0.2 3.6 11.5 2.3 1.4 0.0 3.1 2.8 1.2 4.9 4.9 2.4 0.0 6.0 5.7 0.8 2.5 6.3 1.7 7.7 2.9 29.8 3.1 1.1 7.4 2.6 0.0 0.2 4.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 8.9 0.0 0.0 0.5 0.0 1.1 5.7 5.2 51.4 8.6 4.5 7.3 5.3 4.9 4.6 9.5 5.5 18.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.3 0.0 0.0 0.0 HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617374 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "T-reg: 55.7" "Lineage enriched" "Detected in many" 12 "T-cells: 55.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-1)" "unprognostic (2.62e-2)" "unprognostic (4.10e-1)" "unprognostic (5.67e-3)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-2)" "unprognostic (3.43e-1)" "unprognostic (2.46e-2)" "unprognostic (2.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" 9.7 7.0 3.1 5.0 3.5 8.0 8.8 10.7 4.6 6.8 2.9 31.9 2.8 22.1 3.3 7.8 10.3 3.6 73.0 3.0 6.5 5.0 1.6 9.7 1.3 5.5 5.2 4.3 2.7 0.5 3.7 1.6 5.0 11.9 3.8 2.3 2.7 16.7 36.5 3.0 6.9 25.4 2.4 1.7 15.0 3.5 4.7 2.6 7.6 16.5 1.2 18.1 6.8 8.4 29.3 24.6 6.8 33.4 30.1 5.8 0.6 40.5 24.4 51.9 48.5 16.4 34.6 0.2 5.9 66.4 74.5 7.1 17.3 12.3 28.6 19.1 10.4 67.1 18.4 45.6 39.0 0.3 4.8 14.0 17.2 29.9 11.6 39.8 10.1 35.1 0.6 1.3 69.0 21.0 50.4 6.7 14.6 2.2 6.6 44.7 7.1 0.8 20.5 5.6 7.5 19.1 34.6 0.6 58.9 21.2 24.2 16.7 9.8 30.3 17.4 18.7 18.8 0.9 0.8 0.3 22.3 7.7 4.3 4.7 0.9 0.7 1.2 0.1 0.3 0.4 5.0 1.0 3.0 1.3 0.9 0.7 2.6 3.3 0.3 1.5 55.7 1.3 3.1 3.5 10.7 4.6 3.0 6.5 5.5 5.2 5.0 2.4 4.7 8.4 2.4 28.9 15.0 0.3 0.4 0.0 23.1 0.0 8.0 0.8 6.9 21.6 143.7 10.0 2.5 31.3 0.0 0.5 4.4 0.4 3.9 16.5 11.1 5.6 8.0 5.4 3.6 29.2 10.4 8.0 1.9 7.1 8.2 12.4 6.3 17.5 20.7 1.0 5.4 0.0 11.7 2.5 0.0 2.2 0.0 2.7 1.8 3.6 0.0 5.6 0.8 0.5 1.0 2.5 31.8 15.6 0.8 0.7 0.6 23.9 0.5 2.3 0.7 0.6 0.0 5.7 32.5 7.4 5.2 17.7 0.0 3.0 2.9 10.8 3.5 6.2 HAP1 "HAP2, hHLP1, HIP5, HLP" ENSG00000173805 "Huntingtin associated protein 1" P54257 17 41717742-41734644 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 68.4" "Cell type enriched" "Detected in many" 4 "Glandular and luminal cells: 66.5" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "REH: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023394, HPA076992" Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" Cytosol Nucleoli "HPA023394: AB_1850492, HPA076992: AB_2686822" "unprognostic (2.84e-3)" "unprognostic (3.74e-3)" "unprognostic (2.42e-2)" "unprognostic (2.30e-1)" "unprognostic (7.53e-2)" "unprognostic (4.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.32e-1)" "unprognostic (6.11e-2)" "unprognostic (8.76e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.38e-1)" "unprognostic (2.46e-2)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-2)" "unprognostic (9.29e-2)" 0.6 1.5 24.8 0.3 18.9 0.1 1.0 14.8 21.6 14.5 10.2 2.1 2.7 3.4 1.6 1.1 2.6 1.5 0.1 18.3 58.8 3.3 0.4 0.9 0.2 26.7 26.4 1.2 1.0 0.0 11.6 1.5 24.5 1.9 0.5 0.8 1.5 1.3 0.2 1.6 1.5 0.6 20.3 3.5 11.0 2.1 68.4 2.8 5.0 0.1 0.2 0.5 1.9 16.8 0.2 3.1 1.4 3.1 0.0 0.0 0.3 0.3 0.1 0.6 0.1 1.9 0.2 0.2 1.1 0.2 0.5 13.1 6.7 0.5 0.0 0.0 3.4 0.0 1.8 0.1 0.3 0.0 0.6 0.0 1.6 0.1 0.7 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.1 0.2 1.6 18.7 0.8 96.0 0.0 3.7 0.6 1.0 0.4 0.1 0.7 0.4 0.1 1.5 2.4 0.0 0.0 0.0 1.3 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.0 24.8 18.9 14.8 21.6 18.3 58.8 26.7 26.4 24.5 20.3 68.4 16.8 1.1 0.0 1.7 3.3 0.3 3.1 7.3 1.0 6.8 1.6 1.6 6.7 3.6 0.0 1.9 0.0 2.1 1.5 0.5 1.1 0.0 0.3 0.5 11.5 7.6 3.2 0.0 0.0 1.0 0.9 0.7 3.4 7.7 66.5 0.0 0.2 1.4 0.8 0.5 0.0 5.4 0.6 4.1 0.6 2.2 0.6 0.3 1.2 0.0 0.0 0.4 0.6 2.1 14.6 0.3 1.5 0.2 0.7 0.3 5.3 0.2 0.2 1.7 1.8 0.0 10.6 2.3 0.1 4.7 8.4 3.1 15.7 0.9 0.1 1.1 3.5 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.1;Fibroblasts: 62.1;Langerhans cells: 28.9;Melanocytes: 30.2;Smooth muscle cells: 30.7;Urothelial cells: 89.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HBF TERT88: 157.8;hTEC/SVTERT24-B: 153.8;LHCN-M2: 206.5;U-138 MG: 396.9;U-251 MG: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.7 0.3 0.6 9.0 0.5 0.1 5.3 0.6 0.5 0.7 0.1 4.1 2.8 0.8 1.2 1.6 1.7 7.8 4.0 0.5 1.5 1.1 2.9 3.7 1.6 1.6 2.1 0.2 0.9 0.2 0.3 2.3 1.3 1.1 5.6 0.0 1.0 0.2 0.5 2.3 5.2 3.9 1.1 0.1 2.0 1.8 1.3 0.8 0.7 0.9 0.9 20.5 0.6 0.9 0.3 2.8 0.0 0.4 4.7 11.8 0.0 23.5 17.3 29.9 51.2 0.2 0.4 0.1 0.0 20.8 0.0 4.2 0.0 0.0 157.8 0.1 0.6 0.0 0.6 0.0 19.9 0.0 0.0 31.0 0.0 153.8 14.1 0.7 0.0 0.0 0.0 0.0 206.5 0.3 0.0 0.0 0.4 0.0 3.4 0.0 26.6 0.0 0.0 2.0 0.0 0.4 10.0 0.0 5.6 9.0 0.2 0.3 0.0 396.9 1.4 37.7 123.7 0.0 0.0 0.0 8.5 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.5 0.5 1.5 1.6 2.1 1.3 1.1 1.3 0.9 2.2 0.0 0.0 0.0 0.0 16.3 54.1 1.8 0.6 0.0 0.1 0.4 1.2 0.0 0.2 3.7 0.0 0.2 0.2 1.6 0.0 0.9 19.0 0.1 3.5 7.2 1.2 0.0 0.1 0.0 0.0 62.1 1.1 0.1 13.4 0.0 0.7 0.0 0.3 0.0 0.2 2.3 0.0 0.0 28.9 3.4 1.8 0.7 30.2 0.0 0.0 0.0 0.0 16.1 0.2 1.6 1.9 0.0 0.0 11.0 0.0 0.1 0.0 0.0 0.0 6.9 30.7 0.3 0.1 0.6 11.9 0.1 1.5 0.0 3.9 89.3 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 0.2 0.1 0.0 1.8 0.2 6.0 0.4 0.0 0.1 0.2 0.2 1.1 1.5 0.2 0.1 1.3 0.3 0.2 0.1 0.0 0.0 0.1 0.1 1.4 4.2 0.1 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 1.0 0.0 0.4 0.0 0.6 0.7 1.8 0.4 0.0 1.7 0.9 7.3 0.2 5.3 0.3 0.1 5.1 0.3 0.5 0.2 11.3 12.2 11.1 12.5 0.7 1.4 9.3 10.2 7.8 19.7 19.3 9.6 4.6 27.7 5.7 5.7 7.9 18.0 20.1 9.9 18.7 0.1 16.7 13.8 9.9 5.8 0.5 8.1 13.7 0.9 0.8 14.9 9.2 2.4 9.1 21.6 12.4 23.7 10.1 5.9 16.4 4.8 9.8 8.7 8.3 16.8 13.9 7.4 3.0 7.8 4.4 6.5 8.9 6.1 3.5 9.6 6.1 7.5 4.7 8.7 9.9 9.8 18.1 4.5 5.4 13.4 5.1 11.5 10.7 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "dendritic cells: 87.6;granulocytes: 80.6;Hofbauer cells: 148.3;Kupffer cells: 89.1;Langerhans cells: 67.8;Macrophages: 83.2;monocytes: 49.5;NK-cells: 70.0;Proximal tubular cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;Daudi: 6.4;HDLM-2: 26.3;HMC-1: 6.0;RPMI-8226: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" 14.2 8.2 9.5 19.7 11.1 13.9 5.3 11.1 13.3 4.9 10.4 5.4 4.0 3.2 6.0 3.7 3.3 12.8 2.5 9.1 11.8 26.8 9.8 22.6 32.1 18.0 13.7 1.7 3.0 2.8 1.8 16.9 16.9 2.1 6.8 1.2 2.9 2.9 1.7 2.2 4.9 7.9 16.1 24.1 4.7 2.0 17.5 9.1 1.6 2.1 14.0 13.1 1.2 27.2 0.0 0.2 0.1 0.2 7.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 6.4 0.3 0.0 0.2 0.1 0.0 0.0 0.0 26.3 0.0 1.1 0.1 0.0 0.0 0.0 6.0 0.4 0.4 0.0 0.2 0.0 0.0 0.7 0.1 2.3 0.0 0.1 0.1 3.9 0.2 0.0 0.0 0.1 3.0 21.5 0.3 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.2 0.3 0.0 0.9 0.3 0.3 0.0 0.3 1.8 0.2 0.1 0.7 0.1 16.7 53.8 0.1 14.6 57.9 3.0 1.2 5.9 7.9 137.9 0.5 7.0 9.5 2.5 97.1 36.1 16.4 11.5 43.1 9.5 11.1 11.1 13.3 9.1 11.8 18.0 13.7 16.9 16.1 17.5 27.2 1.2 6.4 6.5 2.0 5.9 1.0 0.2 0.1 0.0 0.9 0.7 1.5 1.1 0.0 1.9 0.0 0.0 0.6 87.6 0.3 7.9 0.1 11.1 0.1 0.1 3.7 0.0 1.3 2.1 0.0 0.8 0.9 0.5 0.1 80.6 0.1 1.1 0.5 148.3 0.0 1.7 0.3 0.0 89.1 67.8 7.8 0.3 83.2 3.6 31.9 49.5 0.1 70.0 1.0 4.8 0.1 0.1 0.0 16.3 0.5 0.1 57.7 0.0 0.2 6.6 0.7 0.5 0.3 0.4 0.1 1.3 1.1 26.3 1.5 0.2 0.3 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 47.5" "Group enriched" "Detected in many" 4 "Early spermatids: 244.6;Excitatory neurons: 376.2;Inhibitory neurons: 442.3;Microglial cells: 334.5;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 233.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 74.1" "Group enriched" "Detected in all" 9 "B-cells: 52.6;dendritic cells: 74.1;monocytes: 24.4" "Cell line enhanced" "Detected in many" "HAP1: 163.6;hTERT-HME1: 79.4;SH-SY5Y: 65.7;U-698: 64.5;WM-115: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 8.2 12.3 5.8 8.8 6.6 5.9 5.1 4.8 7.9 10.1 47.5 5.4 3.4 13.2 6.0 2.9 9.3 6.7 14.3 5.5 3.8 2.8 2.8 5.1 18.9 6.0 6.7 2.4 1.5 1.8 6.5 6.3 6.0 11.0 5.5 25.4 7.1 14.5 16.7 2.2 4.5 13.0 3.8 17.5 8.7 5.6 12.9 6.8 2.9 5.8 18.7 5.2 4.9 7.3 40.2 0.2 6.3 0.1 0.9 8.4 0.2 2.4 23.0 9.5 16.1 0.3 12.7 16.7 41.9 26.0 51.6 5.8 163.6 3.2 24.2 0.2 1.1 0.0 0.2 0.0 0.2 3.5 0.1 3.0 3.1 29.7 79.4 8.4 0.4 2.7 0.0 25.1 13.3 0.0 1.6 3.5 20.3 0.0 3.9 4.7 2.5 10.2 5.2 10.6 11.6 65.7 0.5 0.3 12.7 9.7 0.6 15.2 1.8 34.4 11.1 1.9 22.3 28.8 13.3 64.5 9.0 1.6 69.2 0.3 24.4 0.1 4.2 16.5 4.1 52.6 1.4 2.0 74.1 43.2 0.0 2.1 1.4 5.5 10.3 15.9 5.6 12.9 5.8 6.6 4.8 7.9 5.5 3.8 6.0 6.7 6.0 3.8 12.9 7.3 31.4 6.4 2.8 28.1 46.1 2.4 0.7 6.8 6.2 33.0 1.4 0.8 15.2 0.0 12.9 0.0 16.7 0.1 16.3 15.3 3.9 6.8 244.6 24.2 2.3 16.5 7.2 5.7 376.2 0.7 0.2 5.3 13.7 26.1 1.3 0.0 8.9 1.0 12.9 20.2 442.3 0.7 4.1 51.2 64.2 80.1 1.5 34.8 16.0 334.5 21.0 5.1 11.3 322.7 233.1 10.6 6.7 0.7 46.7 1.6 0.0 0.1 17.5 26.2 6.6 2.3 9.0 34.3 8.7 0.7 2.0 0.1 7.8 0.1 0.3 12.1 HEATR9 "C17orf66, FLJ32830" ENSG00000270379 "HEAT repeat containing 9" A2RTY3 17 35854946-35868891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 10.1" "Group enriched" "Detected in some" 17 "Early spermatids: 88.4;Late spermatids: 36.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA023129 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA023129: AB_1845599" "unprognostic (1.02e-1)" "unprognostic (2.63e-3)" "unprognostic (5.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (7.44e-4)" "unprognostic (1.30e-3)" "unprognostic (2.43e-2)" "unprognostic (2.63e-1)" "unprognostic (3.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.61e-10)" "unprognostic (6.78e-2)" "unprognostic (1.93e-1)" "unprognostic (4.52e-2)" "unprognostic (5.61e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 88.4 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.3 0.0 36.4 0.6 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 837.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" 72.5 108.1 43.1 21.0 49.6 57.9 66.6 48.0 46.0 54.8 47.3 44.5 242.9 43.8 17.4 42.6 49.9 41.4 58.5 40.9 46.0 69.1 145.8 54.6 28.2 52.5 46.5 80.0 75.9 50.2 27.8 34.6 49.9 42.4 21.7 15.2 43.7 36.8 39.3 59.6 165.7 38.7 49.9 58.5 45.1 29.8 46.8 19.5 122.6 37.7 21.4 51.2 50.3 53.5 74.2 46.2 29.3 54.8 229.6 167.6 20.5 65.0 91.0 60.2 79.7 29.8 26.6 21.2 25.2 128.8 51.9 64.7 37.6 54.2 69.1 3.0 30.0 12.0 51.0 74.2 159.1 22.3 11.3 134.7 47.9 80.7 101.9 187.0 124.3 25.1 13.6 19.4 103.9 48.1 18.3 34.9 42.5 71.5 30.0 40.2 85.3 22.1 50.8 74.1 16.6 14.8 85.6 41.1 86.5 84.2 21.3 33.6 140.2 45.7 53.1 72.6 36.2 16.4 14.4 7.9 73.2 38.5 18.8 15.6 65.7 17.2 9.6 49.4 13.5 11.5 16.5 10.4 51.2 11.8 20.6 12.1 21.0 18.7 69.8 25.3 9.7 25.9 43.1 49.6 48.0 46.0 40.9 46.0 52.5 46.5 49.9 49.9 46.8 53.5 120.1 54.5 21.3 2.0 14.9 37.5 56.2 38.3 39.9 43.0 73.3 95.8 26.7 115.8 19.8 57.0 4.2 36.2 14.5 56.5 99.7 89.5 33.8 8.6 27.4 80.4 20.4 174.4 1.5 100.3 27.1 68.6 28.5 14.6 1.3 31.6 162.4 121.7 82.0 6.7 1.7 45.3 18.3 85.4 43.1 13.0 89.2 53.7 62.2 0.0 78.1 44.2 10.3 4.5 3.5 71.1 90.5 94.0 8.0 79.8 837.6 93.0 7.0 6.7 52.6 35.7 40.8 13.8 7.5 44.5 36.1 26.3 14.5 84.3 93.6 54.3 HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 127.5;Inhibitory neurons: 99.4;Microglial cells: 60.0;Oligodendrocyte precursor cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.8" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.8" "Cell line enhanced" "Detected in many" "AF22: 29.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.1" HPA037767 Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA037767: AB_10671378" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.26e-2)" "unprognostic (3.34e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-2)" "unprognostic (9.37e-4)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.54e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.67e-5)" "unprognostic (6.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.84e-2)" 6.6 5.8 6.9 3.7 7.7 1.6 7.3 8.1 8.7 9.0 2.2 8.3 3.0 12.0 11.3 5.3 9.4 7.9 6.0 7.2 5.2 7.1 3.2 6.9 3.4 3.5 3.6 11.8 5.3 7.5 6.9 7.3 1.9 16.8 5.0 11.7 5.7 16.4 5.8 4.6 4.6 12.6 3.3 3.8 5.5 7.0 5.3 3.8 6.7 7.2 2.3 8.2 7.4 6.8 5.8 2.9 29.0 12.0 6.2 6.8 5.2 4.7 6.2 9.2 8.5 0.3 5.4 0.0 3.9 4.8 5.4 0.4 7.9 3.3 11.3 6.3 9.8 3.4 23.1 1.8 3.1 0.7 2.1 7.0 2.9 6.7 5.7 13.0 7.0 7.1 4.5 14.6 14.5 2.7 3.6 1.8 12.1 0.5 2.9 9.0 19.1 3.5 6.5 1.6 6.8 7.2 9.1 2.0 9.4 8.8 13.2 2.0 7.3 9.2 6.3 0.6 8.9 1.0 2.0 8.2 8.1 0.1 5.4 0.0 0.0 0.0 0.4 0.4 0.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.0 2.8 0.1 0.0 0.0 0.2 6.9 7.7 8.1 8.7 7.2 5.2 3.5 3.6 1.9 3.3 5.3 6.8 9.4 0.0 5.1 45.4 3.5 6.1 8.8 3.6 8.6 20.6 6.3 8.4 7.9 4.3 6.0 5.5 27.1 0.4 1.2 1.1 21.5 2.7 2.8 6.8 14.2 8.9 9.0 1.3 127.5 3.7 0.4 12.8 7.1 7.3 3.8 7.8 8.2 1.2 6.5 28.6 99.4 2.7 4.1 7.0 6.5 2.0 12.2 7.0 7.2 60.0 2.3 13.1 0.0 87.0 21.2 2.5 1.4 14.3 4.5 4.9 0.5 1.4 7.2 9.1 13.1 15.8 10.5 9.5 9.5 8.4 4.4 0.4 3.0 4.5 1.2 4.3 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HEY2 "bHLHb32, HERP1, HESR2" ENSG00000135547 "Hes related family bHLH transcription factor with YRPW motif 2" Q9UBP5 6 125747664-125761269 "Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.7" "Cell type enhanced" "Detected in many" "Early spermatids: 49.9;Endometrial ciliated cells: 46.1;Granulosa cells: 73.9;Late spermatids: 80.6;Sertoli cells: 52.6;Smooth muscle cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.5;HEK 293: 7.1;SK-MEL-30: 6.6;TIME: 14.8;U-266/70: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030205, HPA074851" Approved Approved "Nuclear bodies,Aggresome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Aggresome "HPA030205: AB_10600712, HPA074851: AB_2686718" "unprognostic (5.10e-2)" "unprognostic (4.34e-2)" "unprognostic (1.41e-3)" "unprognostic (2.43e-3)" "unprognostic (1.99e-1)" "unprognostic (2.52e-3)" "unprognostic (2.56e-1)" "unprognostic (1.38e-2)" "unprognostic (2.01e-1)" "unprognostic (9.10e-3)" "unprognostic (7.34e-2)" "unprognostic (6.20e-2)" "unprognostic (1.79e-1)" "unprognostic (2.28e-1)" "unprognostic (6.74e-2)" "unprognostic (1.51e-3)" "unprognostic (1.19e-1)" 6.5 0.9 8.8 1.0 12.0 0.1 5.7 9.4 7.6 8.0 3.0 2.5 1.3 7.5 16.4 1.8 13.5 1.7 30.7 7.2 10.4 3.1 5.3 3.2 0.5 12.7 10.0 7.1 3.3 2.6 5.5 3.7 10.6 2.1 1.3 5.7 2.0 2.7 16.2 2.4 2.1 1.7 14.1 1.9 2.0 6.6 11.8 0.7 3.1 4.9 0.6 2.7 4.7 12.2 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.5 7.1 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.6 0.0 0.4 0.0 0.0 3.2 0.0 0.3 0.5 0.6 0.9 0.0 0.1 2.3 0.0 0.0 0.0 6.6 3.2 1.9 0.0 14.8 0.3 0.0 0.1 0.8 17.6 0.3 0.1 0.6 0.0 2.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.8 12.0 9.4 7.6 7.2 10.4 12.7 10.0 10.6 14.1 11.8 12.2 2.8 3.2 1.1 12.4 0.7 3.8 0.5 8.7 3.4 0.4 9.8 5.7 21.5 0.0 2.7 0.0 8.4 0.0 1.4 0.1 9.8 0.1 49.9 46.1 4.2 6.0 0.0 2.7 0.1 1.8 0.1 3.3 1.1 36.8 0.0 73.9 1.8 8.0 0.1 1.7 0.4 0.0 2.0 0.8 3.0 80.6 6.5 0.6 3.6 5.6 0.0 34.8 3.1 2.5 23.4 1.1 0.1 23.3 3.1 0.3 0.0 6.4 5.4 5.2 52.6 17.5 41.8 16.2 15.1 7.7 2.0 0.0 2.0 2.8 0.1 0.3 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.8;Fibroblasts: 95.8;Hepatic stellate cells: 25.0;Muller glia cells: 36.2;Smooth muscle cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 171.6;HHSteC: 135.8;HL-60: 82.4;hTEC/SVTERT24-B: 87.4;Karpas-707: 240.7;U-87 MG: 62.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 7.9 19.8 1.6 6.3 3.3 12.3 5.2 1.5 7.8 7.2 1.8 4.4 2.6 8.1 3.6 2.9 5.4 16.6 4.7 2.9 3.6 11.8 30.3 19.5 2.2 3.6 2.3 1.8 2.1 2.1 2.4 311.9 4.3 7.2 3.4 14.2 2.4 6.4 0.8 0.9 2.3 7.1 1.8 6.5 3.9 2.4 2.9 1.5 5.6 3.9 1.5 10.4 6.3 3.3 0.0 0.0 0.1 0.0 21.6 171.6 0.1 0.7 33.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 135.8 82.4 0.4 41.4 0.0 87.4 0.3 0.0 2.2 0.0 0.1 240.7 0.6 0.0 0.0 56.4 0.0 0.0 0.2 0.8 0.0 7.5 0.0 0.0 0.2 9.3 0.0 0.1 0.0 0.2 0.0 3.5 0.4 2.0 0.0 0.1 0.0 0.1 0.0 0.0 62.6 16.9 0.1 94.0 15.2 3.9 0.0 18.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 3.2 0.0 17.3 1.0 0.0 4.3 1.6 3.3 1.5 7.8 2.9 3.6 3.6 2.3 4.3 1.8 2.9 3.3 6.2 0.0 4.1 16.3 0.0 1.0 0.2 0.0 1.8 0.2 0.3 0.5 1.3 1.5 0.6 0.0 0.0 5.6 0.0 0.0 0.0 0.0 15.2 1.0 23.8 6.2 0.0 2.1 0.3 0.0 4.9 95.8 0.5 0.9 1.3 0.0 25.0 0.5 18.4 0.0 22.4 0.0 0.0 12.5 1.9 2.3 18.3 14.0 1.8 7.5 10.5 36.2 1.0 0.0 0.1 0.0 0.0 10.9 0.3 0.4 0.0 0.0 0.0 0.7 13.1 0.9 26.2 0.2 0.3 0.3 0.1 12.0 0.6 1.3 0.0 0.4 HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 77.2;Cholangiocytes: 125.8;dendritic cells: 57.6;Ductal cells: 107.9;Endothelial cells: 80.0;Hepatic stellate cells: 88.9;Hepatocytes: 58.3;Hofbauer cells: 72.6;Kupffer cells: 63.5" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 87.7;HEL: 99.9;HMC-1: 105.6;HUVEC TERT2: 106.1;K-562: 154.8;NB-4: 101.8;U-937: 79.7" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" 16.2 18.5 5.0 22.2 5.4 84.7 11.2 5.6 8.8 7.1 5.1 7.8 6.4 6.4 3.5 4.1 6.1 27.4 6.1 4.8 5.2 7.0 91.2 16.9 39.1 6.3 5.4 3.0 38.1 1.9 2.2 14.6 6.4 4.7 6.5 0.3 3.5 4.0 2.9 4.6 19.0 5.8 6.2 39.9 5.2 2.4 6.0 4.4 102.1 6.3 30.4 12.7 5.0 6.7 11.2 20.6 10.5 0.1 0.9 0.7 0.2 5.6 46.4 7.4 6.6 4.0 2.6 10.7 87.7 0.7 0.0 2.1 9.5 0.3 9.1 0.1 11.1 99.9 8.8 67.4 21.0 58.6 105.6 0.3 0.2 6.5 0.0 3.7 106.1 0.3 154.8 0.1 0.5 3.2 0.4 101.8 0.2 30.2 11.8 34.0 3.0 0.1 0.9 4.3 4.9 1.0 6.2 0.0 0.1 0.5 3.3 30.6 37.2 0.0 0.6 0.1 0.1 2.6 1.8 21.2 0.0 79.7 51.4 28.0 41.5 61.8 0.8 45.7 0.3 59.3 0.0 0.1 30.8 65.8 0.1 0.1 31.4 1.0 50.7 36.3 0.4 15.5 5.0 5.4 5.6 8.8 4.8 5.2 6.3 5.4 6.4 6.2 6.0 6.7 31.9 0.0 3.0 0.0 77.2 6.4 2.1 0.9 2.2 0.0 3.0 3.2 3.6 125.8 1.6 0.0 0.0 0.7 57.6 0.4 0.0 107.9 0.3 0.8 0.5 80.0 5.3 28.2 0.0 12.0 0.7 2.2 0.5 1.0 7.0 0.0 88.9 58.3 72.6 0.0 0.0 1.6 0.0 63.5 29.1 1.1 0.3 51.7 7.2 5.6 50.4 0.0 9.2 0.5 0.0 10.5 0.0 1.2 1.6 3.2 0.0 0.2 0.9 0.2 0.0 1.9 2.1 0.3 6.3 1.0 3.7 1.1 8.3 3.4 0.7 1.3 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.3;B-cells: 61.5;dendritic cells: 20.3;Kupffer cells: 29.4;Langerhans cells: 59.0;Macrophages: 37.7;monocytes: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.0" "Group enriched" "Detected in many" 11 "B-cells: 21.0;dendritic cells: 17.8;monocytes: 6.0" "Cell line enhanced" "Detected in some" "Daudi: 12.9;HDLM-2: 9.1;REH: 40.5;U-698: 8.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "HPA045038: AB_10959457, HPA076922: " "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (3.83e-2)" "unprognostic (2.60e-1)" "unprognostic (9.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.68e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" "unprognostic (9.95e-2)" "unprognostic (3.65e-2)" "unprognostic (8.70e-2)" "unprognostic (5.94e-2)" 7.1 6.1 0.2 7.8 0.4 1.5 6.5 0.4 0.4 4.9 0.3 3.2 5.0 3.0 1.2 2.3 5.0 2.1 2.2 0.3 1.0 8.0 2.8 12.7 15.1 1.8 0.8 2.8 2.4 0.9 3.5 0.0 1.5 5.0 4.2 0.4 3.2 2.1 0.8 2.8 15.2 1.1 0.8 28.7 4.0 0.4 0.7 7.0 4.5 1.0 19.8 3.0 3.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 12.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 40.5 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 8.2 0.0 0.2 0.0 0.0 1.0 0.0 0.0 6.0 0.0 14.6 0.1 0.3 17.8 21.0 0.3 1.3 0.7 0.2 4.7 5.0 1.0 2.4 0.2 0.4 0.4 0.4 0.3 1.0 1.8 0.8 1.5 0.8 0.7 1.2 7.5 3.2 30.3 0.0 61.5 1.9 0.6 0.1 0.6 0.0 0.5 2.4 1.6 1.5 2.0 3.7 0.0 0.1 20.3 0.3 0.0 6.6 0.1 0.3 0.2 8.5 0.0 2.5 0.0 0.2 0.1 1.2 0.5 0.3 5.1 3.5 1.1 0.0 13.4 0.0 0.0 0.1 2.0 29.4 59.0 0.2 0.3 37.7 0.0 6.5 41.9 0.6 4.1 0.0 0.1 0.3 0.0 0.0 0.9 0.6 0.0 2.9 1.4 0.2 0.0 0.7 0.6 0.0 0.2 0.5 1.1 0.1 4.1 1.0 0.3 1.2 HLA-F ENSG00000204642 "Major histocompatibility complex, class I, F" P30511 6 29722775-29738528 "Plasma proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 220.4;NK-cells: 339.8;Proximal enterocytes: 298.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "A-431: 36.3;GAMG: 13.5;HEK 293: 12.5;HEL: 8.9;HHSteC: 10.1;JURKAT: 7.6;U-266/70: 8.5;U-937: 13.6" NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.07e-3)" "unprognostic (5.16e-2)" "unprognostic (3.05e-1)" "unprognostic (9.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (4.99e-2)" "unprognostic (2.68e-1)" "unprognostic (4.21e-3)" "unprognostic (2.43e-3)" "unprognostic (3.21e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (1.26e-1)" "unprognostic (2.95e-2)" "unprognostic (4.13e-2)" "unprognostic (1.30e-2)" 58.0 36.6 1.3 1.9 1.6 1.8 52.2 1.0 2.0 43.4 1.1 60.4 28.8 41.2 2.3 21.0 38.1 18.7 40.0 1.0 1.2 35.6 29.9 91.8 41.4 1.6 1.3 19.8 14.4 0.2 25.7 1.1 1.5 31.5 2.7 1.0 28.1 2.2 14.7 40.8 101.4 0.3 1.4 188.3 36.2 7.3 1.2 1.9 40.6 0.0 10.2 30.0 38.5 1.6 36.3 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.1 13.5 1.4 0.0 1.3 0.0 0.8 12.5 8.9 0.4 0.1 10.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 7.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.4 2.3 0.0 0.0 0.1 0.0 0.5 1.7 0.0 0.0 0.6 0.1 0.1 1.2 0.2 8.5 1.9 0.1 0.0 13.6 0.1 54.3 16.8 42.8 34.9 21.6 25.9 19.4 22.8 28.5 1.1 16.9 21.5 21.2 31.9 32.7 32.0 6.5 25.1 15.2 1.3 1.6 1.0 2.0 1.0 1.2 1.6 1.3 1.5 1.4 1.2 1.6 180.1 38.5 64.7 2.6 133.4 40.9 32.7 58.4 12.5 1.5 19.9 17.0 12.2 50.1 37.0 7.3 2.1 0.4 220.4 214.3 1.9 75.9 2.2 8.6 13.9 110.6 22.8 29.9 2.7 87.8 0.8 27.3 69.8 14.2 50.0 3.4 71.7 30.4 55.3 0.0 6.2 119.2 69.2 96.9 50.3 1.4 28.3 99.4 28.4 12.2 207.1 4.6 339.8 4.5 0.7 71.4 122.0 21.1 92.3 41.8 298.8 4.9 34.3 1.3 46.0 20.7 36.2 10.0 3.9 11.4 37.5 0.3 198.9 24.9 90.8 62.5 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMG20B "BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL" ENSG00000064961 "High mobility group 20B" Q9P0W2 19 3572777-3579088 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 265.7;Melanocytes: 229.5;Syncytiotrophoblasts: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 411.1;WM-115: 405.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050220, HPA053157, HPA069832" Approved Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA050220: AB_2681056, HPA053157: AB_2682061, HPA069832: AB_2686210" "unprognostic (2.97e-1)" "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.72e-7)" "unprognostic (2.18e-2)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-1)" "unprognostic (1.66e-1)" "unprognostic (4.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.91e-3)" "unprognostic (2.78e-2)" "unprognostic (1.84e-1)" "prognostic favorable (2.89e-5)" 50.4 41.4 27.3 18.2 29.3 30.1 49.9 29.1 33.7 50.9 29.4 59.0 28.1 54.5 15.6 48.1 44.7 16.8 36.8 26.0 27.5 56.0 54.4 38.3 20.1 32.6 28.4 38.0 38.1 30.3 18.1 22.7 31.8 68.9 17.2 8.8 49.9 25.6 25.9 58.3 47.6 19.9 29.6 39.2 54.2 36.0 30.3 48.2 39.3 12.0 15.9 49.0 43.8 34.1 93.1 39.0 34.6 83.0 42.2 38.1 64.1 58.7 42.4 52.6 40.0 14.1 33.5 50.5 53.7 42.6 47.5 44.4 20.3 40.0 31.3 45.1 46.6 24.8 132.2 37.7 27.2 33.9 117.5 32.5 47.0 30.2 20.0 53.4 53.4 44.8 42.0 81.9 35.0 126.3 64.7 62.0 39.7 78.5 78.4 42.3 60.4 69.5 39.0 58.4 21.7 66.0 81.7 141.3 411.1 32.4 106.8 90.5 77.4 27.7 62.1 99.3 50.8 76.4 43.0 36.2 72.0 85.6 405.1 44.9 68.1 66.2 40.1 70.1 35.8 35.2 34.1 43.6 66.1 30.2 36.3 35.3 37.9 59.5 77.0 59.5 41.4 51.8 27.3 29.3 29.1 33.7 26.0 27.5 32.6 28.4 31.8 29.6 30.3 34.1 50.1 28.9 19.3 9.8 27.9 70.5 52.1 67.4 47.8 3.4 75.0 70.9 8.7 28.6 40.0 18.4 10.4 122.9 34.1 50.0 92.0 65.0 26.7 39.7 41.4 42.5 66.8 24.4 0.7 45.5 265.7 35.4 32.6 44.4 37.5 58.1 38.6 20.9 81.9 8.4 0.7 170.8 57.0 29.6 93.4 49.6 37.3 47.1 229.5 3.7 86.2 41.2 42.2 0.5 11.7 58.6 68.5 44.8 34.9 62.8 74.7 76.2 29.5 18.7 32.9 22.4 53.4 39.9 17.4 53.0 79.8 303.7 30.8 49.6 68.7 62.9 HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 275.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 947.5;Cytotrophoblasts: 894.3;Pancreatic endocrine cells: 1838.5;Prostatic glandular cells: 1483.3;Syncytiotrophoblasts: 822.8;Urothelial cells: 1681.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" 28.1 9.0 22.1 79.6 20.9 184.0 27.4 17.8 27.3 93.3 2.6 59.9 118.7 22.8 16.7 275.1 41.0 39.2 35.8 24.1 23.3 89.2 20.0 46.5 139.3 24.3 19.1 4.7 31.9 15.0 15.4 82.4 21.1 27.7 57.2 32.2 69.7 12.6 119.7 141.6 103.6 9.7 15.4 68.7 73.3 80.1 22.9 156.0 31.5 35.1 154.7 100.1 109.6 25.2 1418.7 547.0 274.2 192.9 124.8 916.6 1193.8 556.0 628.8 421.5 233.4 361.3 960.0 658.9 273.1 229.1 264.0 294.7 326.2 991.8 332.3 146.0 228.2 202.6 177.1 488.2 263.7 732.1 227.3 396.1 109.4 765.1 395.8 1083.8 1290.0 369.3 832.0 32.9 596.0 143.0 650.0 898.8 1340.9 697.5 950.3 947.6 6.2 728.0 286.6 128.4 477.0 202.5 59.3 278.3 533.3 430.2 112.2 775.8 1132.1 218.5 691.2 321.3 528.0 260.5 444.5 867.4 461.2 301.7 1115.0 18.7 26.6 35.5 24.4 26.8 32.2 63.5 45.0 39.0 79.6 39.5 52.0 42.9 6.7 20.1 26.5 86.6 55.8 30.7 22.1 20.9 17.8 27.3 24.1 23.3 24.3 19.1 21.1 15.4 22.9 25.2 11.0 28.9 21.7 2.3 117.8 432.3 947.5 181.3 109.8 29.0 88.8 47.4 30.8 28.6 106.1 40.5 4.2 894.3 70.3 173.5 46.9 755.3 7.2 50.5 14.6 113.9 117.0 268.3 5.4 277.5 799.8 72.0 79.5 115.3 66.7 8.3 18.2 12.3 377.2 11.8 5.7 226.4 97.6 74.0 149.9 24.5 5.6 94.3 90.7 1.0 74.3 44.1 33.0 4.5 2.7 1838.5 249.1 2.6 198.2 1483.3 174.5 15.8 21.7 41.9 0.0 18.6 77.7 40.2 417.6 224.7 361.4 822.8 66.6 0.9 364.3 1681.0 HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 49.9;Excitatory neurons: 80.7;Inhibitory neurons: 76.2;Oligodendrocytes: 23.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" 1.4 3.6 6.1 0.2 5.9 0.0 1.4 5.9 5.2 0.8 0.0 0.8 0.2 0.2 0.0 1.0 0.4 0.6 1.8 5.5 10.6 0.9 0.7 2.6 0.3 5.6 6.3 0.4 1.6 0.1 4.7 6.2 6.6 3.0 0.8 4.5 0.8 1.0 1.1 0.1 0.9 0.5 9.2 0.0 1.0 2.6 8.3 0.6 0.4 2.8 0.2 0.9 0.7 9.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.9 5.9 5.2 5.5 10.6 5.6 6.3 6.6 9.2 8.3 9.4 0.6 0.0 1.3 49.9 0.0 0.0 0.0 0.0 1.2 15.1 3.7 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.5 0.0 0.0 80.7 0.0 0.0 5.8 0.0 0.0 0.0 3.5 3.9 0.0 0.1 0.0 76.2 0.0 0.0 0.3 0.0 1.3 0.3 0.1 0.0 15.0 0.0 1.5 0.0 5.5 23.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.9 5.6 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686431-37745105 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.1;pancreas: 33.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Collecting duct cells: 57.0;Distal tubular cells: 45.0;Ductal cells: 42.0;Early spermatids: 32.3;Glandular and luminal cells: 41.7;Pancreatic endocrine cells: 31.7;Proximal tubular cells: 38.2" "Cancer enhanced" "Detected in many" "renal cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 139.3" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in single" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB068192: AB_2665649, HPA002083: AB_1080232" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (5.29e-3)" "unprognostic (5.29e-2)" "unprognostic (3.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "prognostic favorable (6.00e-4)" "unprognostic (7.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.49e-2)" "prognostic favorable (2.51e-6)" 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.7 0.0 9.9 6.9 1.5 7.5 0.0 5.7 15.1 0.0 0.0 0.1 61.1 12.9 6.8 0.0 0.0 0.0 0.0 33.0 3.5 0.0 0.0 0.0 2.3 7.1 0.0 0.0 4.4 0.0 0.0 8.6 0.1 0.0 0.0 8.2 3.9 0.1 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 2.2 0.0 28.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 139.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.6 14.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.6 78.6 1.9 57.0 0.0 0.0 0.0 15.4 45.0 42.0 32.3 18.5 3.6 0.4 14.4 0.0 0.2 25.4 0.0 0.2 13.7 41.7 5.7 0.0 0.0 5.1 0.1 0.0 0.2 13.5 0.0 0.3 0.0 11.6 0.6 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.1 31.7 11.4 0.0 0.0 2.6 14.3 38.2 3.7 0.0 0.0 0.0 0.3 3.0 2.5 0.0 0.0 0.0 0.6 0.0 20.4 2.7 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 215.9;Endometrial ciliated cells: 184.4;Glandular and luminal cells: 151.9" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 52.7;Karpas-707: 92.6;SCLC-21H: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" 1.5 6.3 6.5 1.1 7.6 4.6 26.9 8.2 12.8 23.1 69.8 3.2 8.5 8.4 33.7 21.2 25.9 12.8 21.9 16.2 7.8 7.2 46.4 5.3 1.3 5.7 4.6 2.6 226.2 5.1 7.7 0.6 5.7 57.7 1.0 6.4 71.2 4.6 108.7 45.0 1.3 1.4 4.1 4.8 55.4 6.1 6.0 3.0 28.9 55.9 3.6 1.3 11.7 8.0 16.6 6.9 7.2 18.9 0.2 0.1 1.1 1.1 0.0 1.7 0.6 1.2 11.5 0.1 8.8 8.4 8.3 9.1 52.7 24.9 1.2 45.1 33.5 10.6 0.4 8.3 0.7 0.4 32.6 1.8 37.4 0.6 2.1 1.9 0.0 20.6 0.4 92.6 7.0 48.4 3.2 1.1 11.4 1.4 5.1 2.2 11.5 5.5 25.3 20.1 50.8 13.1 18.6 14.1 17.6 5.2 17.1 3.5 0.2 17.2 31.7 1.3 15.3 11.8 5.9 1.8 29.0 0.4 6.4 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.3 0.1 0.0 0.4 0.0 0.0 0.5 0.2 0.3 6.5 7.6 8.2 12.8 16.2 7.8 5.7 4.6 5.7 4.1 6.0 8.0 1.9 16.0 10.1 24.8 3.8 4.6 56.1 7.2 10.2 15.0 39.7 20.4 23.0 215.9 14.6 11.0 18.8 1.1 4.4 0.3 7.9 29.6 1.9 184.4 15.4 12.4 3.0 8.2 24.8 76.5 0.4 3.6 14.3 151.9 0.0 11.9 1.4 59.6 13.3 20.2 35.1 0.4 0.0 3.2 73.9 4.0 1.8 9.2 37.4 7.5 7.9 18.5 1.0 6.6 11.8 25.9 0.1 0.7 4.1 81.5 0.7 12.1 4.0 5.1 0.0 7.8 4.8 5.5 16.6 19.4 6.0 0.7 3.1 4.1 0.4 30.5 HOXB13 ENSG00000159184 "Homeobox B13" Q92826 17 48724763-48728750 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 41.1;prostate: 82.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 144.7;Enteroendocrine cells: 195.2;Intestinal goblet cells: 77.0;Paneth cells: 71.3;Prostatic glandular cells: 61.9;Undifferentiated cells: 81.6" "Cancer enriched" "Detected in many" 17 "prostate cancer: 187.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "PC-3: 173.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004438, HPA062852, HPA065019" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB004438: AB_627744, HPA062852: AB_2684880, HPA065019: AB_2685406" "unprognostic (4.81e-2)" "unprognostic (2.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.33e-2)" "unprognostic (5.85e-3)" "unprognostic (1.88e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (1.17e-2)" "unprognostic (6.65e-2)" "unprognostic (1.74e-1)" "unprognostic (4.27e-2)" "unprognostic (4.73e-11)" "unprognostic (1.39e-2)" "unprognostic (4.50e-2)" "unprognostic (1.12e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 82.3 41.1 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 4.6 0.0 1.9 6.0 0.0 13.2 0.0 0.0 0.5 0.6 0.0 0.2 0.0 2.5 3.0 0.0 3.0 0.0 1.4 0.0 8.7 0.0 0.1 1.0 4.2 2.5 1.5 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.7 0.0 0.0 0.3 0.0 2.2 173.0 0.0 1.4 0.1 0.0 0.4 0.0 0.0 2.7 0.0 4.4 0.5 0.0 0.5 0.0 0.5 4.7 4.7 1.3 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 144.7 0.0 0.0 0.6 0.0 0.0 0.2 195.2 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 77.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.3 0.0 0.0 61.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.1 0.2 0.1 81.6 14.6 HOXB6 "HOX2, HOX2B" ENSG00000108511 "Homeobox B6" P17509 17 48595751-48604992 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 40.3;kidney: 60.2" "Group enriched" "Detected in many" 4 "Collecting duct cells: 136.1;Distal tubular cells: 113.5;Endometrial ciliated cells: 80.7;Glandular and luminal cells: 56.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 32.7" "Group enriched" "Detected in some" 17 "medulla oblongata: 12.9;spinal cord: 22.6;white matter: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 28.2;HEK 293: 80.3;RPTEC TERT1: 53.2;TIME: 30.1" "Region enriched" "Detected in single" 102 "pons and medulla: 10.1" "Group enriched" "Detected in some" 168 "medulla oblongata: 8.1;spinal cord: 25.4" HPA042063 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA042063: AB_10796470" "unprognostic (5.01e-2)" "unprognostic (4.48e-2)" "unprognostic (1.99e-1)" "prognostic favorable (2.46e-4)" "unprognostic (1.30e-1)" "unprognostic (8.80e-3)" "unprognostic (5.64e-2)" "unprognostic (2.06e-3)" "unprognostic (3.97e-2)" "unprognostic (1.84e-2)" "unprognostic (6.97e-2)" "unprognostic (6.64e-2)" "unprognostic (2.50e-3)" "unprognostic (2.53e-3)" "unprognostic (5.76e-2)" "unprognostic (7.11e-2)" "unprognostic (4.19e-3)" 10.2 7.4 0.2 4.4 0.1 0.2 4.6 0.3 0.2 18.3 0.0 16.1 1.0 4.3 40.3 0.3 13.4 0.3 0.7 0.1 0.0 60.2 0.8 6.2 0.4 12.9 0.0 0.3 1.2 1.3 0.1 2.6 0.8 2.0 6.1 0.0 0.2 21.1 1.7 1.2 14.0 2.3 22.6 3.0 9.3 1.1 0.1 0.0 0.7 0.5 0.0 3.8 2.2 6.3 5.2 11.9 0.0 6.2 5.3 5.5 0.1 0.0 0.0 0.0 0.0 6.5 7.7 0.0 28.2 14.2 2.0 0.1 1.4 0.4 0.0 0.2 80.3 7.1 23.8 0.0 7.9 0.6 18.0 6.9 0.2 11.4 0.2 4.3 5.4 0.5 4.7 0.1 15.7 0.3 0.0 0.3 0.0 20.0 4.7 0.0 13.1 0.7 53.2 2.6 0.0 0.0 4.4 0.0 8.2 0.1 2.1 2.5 30.1 1.0 6.0 5.0 22.2 0.0 0.0 0.1 0.9 0.0 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.1 0.0 12.9 0.0 0.8 22.6 0.1 6.3 10.6 0.0 0.0 0.0 0.4 0.8 0.5 0.0 0.0 0.0 0.4 0.5 0.4 0.0 0.0 136.1 0.0 0.2 0.0 18.1 113.5 0.1 1.0 80.7 5.5 10.6 7.7 0.4 0.0 2.0 2.9 3.0 0.0 56.4 0.0 0.0 4.2 0.0 1.7 0.0 0.0 9.0 0.0 18.6 3.1 0.3 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.8 0.0 0.0 0.6 9.5 2.8 0.0 0.0 0.0 0.9 6.4 4.8 6.2 0.0 1.1 0.3 1.2 0.0 11.0 1.2 HOXB7 "HOX2, HOX2C" ENSG00000260027 "Homeobox B7" P09629 17 48607232-48633572 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "epididymis: 135.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Distal enterocytes: 131.3;Distal tubular cells: 148.7;Endometrial ciliated cells: 82.9;Glandular and luminal cells: 73.1;Intestinal goblet cells: 77.6;Paneth cells: 67.8;Proximal enterocytes: 140.3;Undifferentiated cells: 63.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 5.6;spinal cord: 13.3;white matter: 7.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 81.9;OE19: 74.7;RPTEC TERT1: 66.5;SK-MEL-30: 84.3" "Region enriched" "Detected in single" 58 "pons and medulla: 5.7" "Region enriched" "Detected in some" 7 "spinal cord: 22.2" HPA049940 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA049940: AB_2616461" "unprognostic (6.76e-2)" "unprognostic (6.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-3)" "unprognostic (1.42e-2)" "unprognostic (1.69e-2)" "unprognostic (8.05e-3)" "unprognostic (9.16e-2)" "unprognostic (9.91e-2)" "unprognostic (7.01e-3)" "unprognostic (7.81e-3)" "unprognostic (1.17e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "prognostic favorable (2.39e-4)" 13.2 11.0 0.1 3.9 0.1 0.2 12.4 0.0 0.3 21.8 0.1 16.9 1.1 5.2 135.1 0.4 8.7 0.7 0.3 0.1 0.1 30.4 0.4 2.2 2.7 5.6 0.1 0.5 0.8 5.5 0.1 5.8 1.1 2.4 15.9 0.0 0.2 16.9 1.7 3.3 18.1 6.7 13.3 3.0 5.9 1.9 0.3 0.2 0.4 0.2 0.9 7.7 5.5 7.5 48.1 20.6 0.0 0.5 14.2 21.1 0.0 0.0 0.0 0.2 0.8 31.9 0.9 0.9 81.9 19.9 23.9 6.9 0.1 0.0 0.0 22.3 15.1 7.4 15.4 0.0 11.7 0.0 14.8 13.8 6.3 14.2 0.0 3.5 43.8 14.7 8.0 0.3 46.0 12.5 1.0 0.4 0.0 74.7 0.1 0.0 39.2 5.5 66.5 15.8 0.0 0.1 16.0 0.0 84.3 1.1 3.8 4.7 38.1 0.0 24.8 20.5 36.9 2.6 6.3 0.1 0.4 0.0 58.6 0.0 0.0 0.0 1.5 0.0 0.8 0.7 0.2 0.8 0.0 1.4 0.0 0.5 0.0 1.0 0.0 0.7 2.1 0.2 0.1 0.1 0.0 0.3 0.1 0.1 5.6 0.1 1.1 13.3 0.3 7.5 55.4 0.0 0.0 0.0 2.0 5.5 0.9 0.0 0.6 0.0 0.9 1.0 0.3 0.0 0.0 86.5 0.0 6.8 1.6 131.3 148.7 0.1 0.3 82.9 6.3 20.3 36.5 1.3 0.0 1.3 19.3 6.4 0.0 73.1 5.1 0.0 1.4 0.2 11.5 0.0 0.0 77.6 0.0 10.6 5.4 0.2 0.6 2.8 24.9 0.0 1.7 0.0 2.1 0.0 0.0 0.3 67.8 0.0 5.1 0.6 140.3 31.6 0.0 0.0 0.0 3.5 8.9 1.7 20.9 0.2 2.0 1.8 2.6 0.1 63.1 3.5 HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 6.6;Collecting duct cells: 9.2;Distal tubular cells: 15.6;Early spermatids: 14.4;Endothelial cells: 6.5;Theca cells: 4.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in many" 8 "medulla oblongata: 8.9;pons: 5.7;spinal cord: 5.7;white matter: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HSkMC: 11.2;RPTEC TERT1: 12.0;SCLC-21H: 14.5;SH-SY5Y: 10.1" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 4.1;pons: 1.1;spinal cord: 3.0" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: AB_2685083" "unprognostic (1.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.57e-4)" "unprognostic (1.47e-3)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (7.44e-2)" 3.2 2.3 0.2 0.8 0.4 0.0 2.8 0.4 0.3 3.2 0.1 1.0 0.3 6.9 42.1 0.7 6.8 0.6 0.2 0.2 0.4 7.9 0.0 0.2 0.8 8.9 0.8 5.5 0.2 0.1 0.0 0.1 5.7 1.7 0.6 0.0 0.5 7.1 0.7 0.9 0.8 4.1 5.7 0.7 0.3 1.7 0.4 0.2 0.4 0.0 0.2 1.0 2.0 4.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.7 0.2 0.0 0.4 0.0 0.0 0.1 3.6 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.9 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 12.0 0.9 14.5 10.1 0.2 0.1 4.6 0.2 0.0 0.0 1.0 0.2 0.2 1.5 0.8 0.0 0.2 0.0 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.3 0.2 0.4 8.9 0.8 5.7 5.7 0.4 4.9 6.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.3 15.6 0.0 14.4 0.1 2.1 6.5 1.2 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 3.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 0.3 4.5 0.0 0.1 0.3 2.9 0.0 0.0 0.0 1.3 1.1 0.8 0.5 0.0 1.3 0.0 0.1 4.7 0.6 0.1 HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.4;epididymis: 28.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Collecting duct cells: 16.5;Early spermatids: 3.7;Endothelial cells: 3.6;Leydig cells: 4.7;Proximal tubular cells: 6.5;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in many" 21 "medulla oblongata: 10.6;pons: 5.6;spinal cord: 8.1;white matter: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 16.6;HEK 293: 39.7;RPTEC TERT1: 29.6;SK-MEL-30: 11.0" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 6.0;spinal cord: 7.8" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" 6.9 8.3 0.0 1.6 0.0 0.0 7.4 0.0 0.1 7.1 0.0 7.3 1.0 24.4 28.0 1.1 14.3 1.5 0.6 0.0 0.0 18.5 0.0 0.4 1.7 10.6 0.3 15.1 0.6 0.1 0.0 0.4 5.6 2.9 2.0 0.0 0.7 11.1 2.8 2.4 6.2 9.7 8.1 7.2 1.0 3.0 0.0 0.2 1.2 0.5 0.4 2.7 4.0 7.3 0.5 0.3 0.0 0.0 2.0 3.0 0.0 0.2 0.9 0.1 1.1 0.9 0.0 0.0 16.6 3.4 0.7 0.2 2.6 0.0 0.4 0.0 39.7 0.5 0.0 0.0 0.5 0.0 0.1 9.3 2.6 0.0 0.5 0.2 6.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 29.6 4.1 2.5 4.2 0.6 0.0 11.0 0.6 0.0 0.0 5.0 0.5 0.2 2.9 2.1 0.0 0.1 0.0 2.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.3 5.6 8.1 0.0 7.3 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 3.7 0.1 1.1 3.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.7 2.6 4.7 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 0.0 0.1 0.3 6.5 0.0 0.0 6.6 0.6 0.9 0.3 0.4 0.0 0.6 0.0 0.1 3.0 1.3 0.0 HOXD8 "HOX4, HOX4E" ENSG00000175879 "Homeobox D8" P13378 2 176129694-176132695 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 99.6;kidney: 76.2" "Cell type enhanced" "Detected in many" "Adipocytes: 51.8;Collecting duct cells: 60.7;Distal tubular cells: 213.2;Early spermatids: 124.6;Leydig cells: 51.3;Peritubular cells: 53.8;Spermatocytes: 82.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.5;spinal cord: 4.0;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 45.4;RPTEC TERT1: 74.8;TIME: 32.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 70 "spinal cord: 34.6" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.22e-1)" "unprognostic (6.31e-2)" "unprognostic (2.19e-3)" "unprognostic (2.68e-2)" "unprognostic (3.35e-1)" "unprognostic (3.49e-1)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.78e-4)" "unprognostic (2.79e-1)" "unprognostic (1.40e-2)" "unprognostic (3.93e-1)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (4.80e-2)" "unprognostic (5.21e-2)" "unprognostic (8.31e-2)" "unprognostic (2.80e-2)" 16.4 20.6 0.0 4.8 0.0 0.0 18.8 0.0 0.0 13.3 0.0 10.8 1.2 19.5 99.6 2.7 17.2 3.1 0.9 0.0 0.0 76.2 0.3 0.9 4.9 1.5 0.0 34.2 1.4 1.1 0.0 0.7 0.8 6.0 4.9 0.0 1.7 24.0 7.8 4.8 8.6 13.1 4.0 10.5 1.6 20.1 0.0 1.0 3.5 1.5 1.3 6.5 9.2 5.8 13.7 2.1 0.0 0.0 8.8 14.1 0.3 1.7 7.2 2.2 0.2 0.1 0.1 0.0 16.7 10.8 1.7 0.1 4.7 0.5 5.4 0.0 6.4 2.3 0.8 0.0 2.9 1.3 0.8 24.7 45.4 0.3 6.7 0.0 22.9 4.4 0.2 0.1 3.7 0.1 0.1 0.4 0.2 0.0 2.6 0.0 4.9 0.2 74.8 9.6 14.2 26.4 4.3 0.0 28.4 1.2 0.0 0.1 32.5 1.1 8.9 15.4 9.1 0.0 0.0 0.0 21.1 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 4.0 0.0 5.8 51.8 0.0 1.1 0.0 0.5 2.7 2.1 0.0 0.6 0.0 0.7 0.6 2.3 0.0 0.0 60.7 0.0 0.0 0.2 2.7 213.2 0.0 124.6 0.7 9.4 36.4 4.8 0.0 0.0 0.0 0.0 14.9 0.0 0.3 0.0 0.0 2.5 0.0 0.1 0.0 0.0 1.8 0.0 0.0 3.4 29.9 51.3 0.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 53.8 0.0 1.3 0.5 25.1 0.7 0.0 32.9 14.1 9.8 82.1 20.4 0.2 2.8 0.1 1.0 31.9 3.4 1.1 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;ovary: 31.9" "Cell type enhanced" "Detected in many" "Club cells: 112.0;granulocytes: 96.3;Granulosa cells: 285.0;Peritubular cells: 90.3;Urothelial cells: 92.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.4" "Group enriched" "Detected in some" 36 "memory B-cell: 14.9;naive B-cell: 26.6;plasmacytoid DC: 42.3" "Group enriched" "Detected in many" 108 "B-cells: 26.6;dendritic cells: 42.3" "Cell line enhanced" "Detected in some" "A-431: 5.8;CAPAN-2: 20.6;HaCaT: 6.0;RPTEC TERT1: 13.2;RT4: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" 2.6 2.5 2.3 2.7 1.9 2.0 1.9 25.4 6.9 2.4 0.0 2.1 3.7 3.4 1.3 11.6 4.4 12.7 1.9 1.6 4.7 5.9 0.4 1.8 2.3 4.7 3.3 31.9 1.0 0.1 4.7 0.7 3.8 2.0 1.1 1.0 5.6 1.5 0.4 0.5 2.9 0.9 4.4 3.3 6.5 1.3 5.8 1.3 1.6 0.2 1.2 14.5 2.6 6.1 5.8 1.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.6 0.0 0.4 0.0 0.0 6.0 0.0 2.8 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.1 1.6 2.2 1.2 0.0 0.0 13.2 14.5 4.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 14.9 0.0 0.0 0.7 26.6 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.1 2.3 1.9 25.4 6.9 1.6 4.7 4.7 3.3 3.8 4.4 5.8 6.1 3.5 3.2 5.8 0.0 13.1 9.1 13.5 70.1 5.2 3.7 2.4 9.3 3.2 32.9 112.0 20.2 4.2 0.5 21.6 5.2 0.0 25.0 1.7 3.6 1.0 28.9 2.4 0.0 13.4 2.1 42.1 13.2 23.9 14.9 96.3 285.0 25.0 0.4 37.6 1.7 35.0 7.2 71.2 3.5 3.7 2.0 8.7 12.5 1.8 6.5 4.9 32.9 8.2 24.1 0.7 51.9 6.5 90.3 0.0 5.6 2.7 19.1 61.2 2.6 0.0 0.5 17.5 5.4 5.6 36.6 8.1 1.4 1.4 68.5 4.3 92.9 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 10.7;Horizontal cells: 21.9;Suprabasal keratinocytes: 9.1;Urothelial cells: 24.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.5 0.0 0.0 0.0 14.4 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 1.4 0.0 0.0 1.9 0.0 0.3 75.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 4.1 10.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 3.4 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.7 1.8 0.0 0.2 0.0 6.3 0.0 0.0 4.5 10.7 0.5 0.1 0.0 0.0 0.1 0.0 0.4 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 21.9 0.1 0.9 4.1 0.0 1.5 1.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 0.0 2.7 0.2 0.2 5.0 0.2 0.0 0.0 0.3 0.0 0.0 4.5 9.1 0.1 0.1 0.0 1.7 24.9 HS6ST2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626016-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;kidney: 13.9;ovary: 14.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.7;Excitatory neurons: 37.5;Inhibitory neurons: 44.2;Leydig cells: 62.7;Oligodendrocyte precursor cells: 54.3;Peritubular cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 46.2;HeLa: 28.1;RH-30: 66.1;RT4: 33.7;SH-SY5Y: 82.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" 0.2 2.4 12.4 0.6 10.0 0.0 2.0 1.2 7.4 1.0 0.0 0.6 0.1 3.5 2.4 3.9 1.8 0.3 0.2 9.6 10.7 13.9 0.0 0.7 0.1 6.3 22.5 14.1 5.3 0.3 1.1 8.4 7.3 2.8 0.8 1.5 0.9 0.8 6.2 0.2 0.1 1.5 4.9 0.0 0.9 2.9 20.3 0.6 0.4 0.9 0.5 2.5 0.7 2.6 10.7 0.1 14.5 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 0.0 0.0 15.2 0.0 0.0 0.5 21.7 0.1 0.0 0.0 46.2 0.1 28.1 0.0 0.0 0.0 0.0 0.7 20.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 7.8 0.3 0.1 11.8 7.2 0.6 0.0 66.1 0.0 13.3 33.7 1.8 82.0 14.8 0.0 0.1 23.7 0.0 0.1 0.0 0.0 2.6 9.6 23.8 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.4 10.0 1.2 7.4 9.6 10.7 6.3 22.5 7.3 4.9 20.3 2.6 0.0 0.0 0.0 1.6 0.0 0.3 0.2 1.8 6.8 0.2 4.3 2.4 0.8 0.0 5.5 3.7 0.0 35.7 0.2 0.3 5.9 0.0 0.5 0.3 0.6 0.5 0.0 0.0 37.5 2.0 2.6 2.6 0.0 0.1 0.0 0.1 0.0 0.0 3.4 0.0 44.2 0.2 2.0 0.0 0.0 1.1 62.7 0.2 0.0 10.3 0.0 5.3 0.0 54.3 1.4 0.8 0.2 35.3 0.0 1.3 0.0 0.1 9.8 0.4 0.0 17.9 0.3 0.3 1.1 11.1 0.3 17.4 0.1 0.3 0.2 1.8 HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Cell line enhanced" "Detected in many" "HHSteC: 162.8;SK-MEL-30: 100.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" 9.6 17.4 18.4 2.9 17.8 2.9 9.6 19.9 26.4 10.0 23.4 16.0 6.7 7.6 11.1 17.4 8.7 5.7 6.7 17.2 18.1 18.6 29.7 10.7 4.2 19.1 18.5 6.6 20.4 19.7 6.7 9.9 19.6 10.2 13.1 14.8 12.8 7.6 12.5 16.0 6.5 5.7 18.1 5.2 10.1 0.8 20.3 4.3 8.9 10.6 4.9 6.2 10.6 17.2 32.2 8.6 0.3 0.5 4.6 15.4 12.7 14.3 32.2 14.8 13.0 16.5 21.7 0.0 3.6 18.8 0.2 18.3 28.5 18.9 7.0 30.6 6.7 0.0 8.8 9.6 162.8 0.0 0.0 18.0 49.6 1.7 10.8 31.5 0.3 4.8 0.0 0.0 0.7 26.8 0.1 0.0 0.0 17.6 30.1 0.3 0.0 0.0 53.7 7.6 0.5 1.8 15.2 20.9 100.2 1.4 11.9 7.6 0.0 0.1 0.0 0.4 0.1 0.0 16.7 0.0 0.2 8.9 0.6 31.9 6.8 8.6 5.8 4.4 6.9 2.2 10.1 6.2 2.8 2.5 26.0 14.0 0.4 5.2 1.6 3.3 4.9 6.2 18.4 17.8 19.9 26.4 17.2 18.1 19.1 18.5 19.6 18.1 20.3 17.2 36.4 54.5 34.5 12.1 5.0 39.8 66.0 135.5 67.2 12.0 89.8 93.6 12.4 48.6 109.2 49.7 22.9 126.6 9.6 119.8 68.4 63.8 1.3 47.2 13.2 23.0 11.5 11.4 5.7 62.1 67.1 16.0 31.6 59.4 19.0 37.2 30.0 122.5 44.7 20.2 11.0 81.3 71.2 20.5 18.0 1.3 19.9 16.0 39.2 6.5 4.0 33.2 6.2 1.0 3.1 137.3 99.6 24.5 2.3 80.2 70.6 80.6 80.3 33.0 0.0 6.3 15.9 1.3 1.3 46.8 57.8 117.4 12.2 34.5 99.6 104.4 HSD17B13 "SCDR9, SDR16C3" ENSG00000170509 "Hydroxysteroid 17-beta dehydrogenase 13" Q7Z5P4 4 87303789-87322886 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 573.7" "Cell type enhanced" "Detected in many" "Adipocytes: 100.0;Club cells: 42.9;Hepatocytes: 131.3;Respiratory ciliated cells: 34.0;Urothelial cells: 57.0" "Cancer enriched" "Detected in some" 26 "liver cancer: 52.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "NB-4: 1.4" "Not detected" "Not detected" HPA029125 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA029125: AB_10601580" "unprognostic (2.49e-1)" "unprognostic (7.46e-2)" "unprognostic (7.02e-2)" "unprognostic (1.86e-4)" "unprognostic (4.74e-2)" "unprognostic (8.44e-2)" "prognostic favorable (2.94e-4)" "prognostic favorable (7.80e-4)" "unprognostic (4.97e-1)" "unprognostic (2.22e-2)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (7.18e-4)" "unprognostic (3.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.52e-3)" 9.4 0.3 0.6 0.2 0.6 1.4 6.4 2.4 1.0 2.7 0.1 0.7 0.4 2.7 0.2 0.2 1.0 0.2 0.4 0.6 0.5 0.4 573.7 3.6 0.2 0.8 0.5 0.5 1.8 0.1 0.2 0.8 0.9 4.5 0.4 0.8 0.2 0.2 0.3 6.5 0.7 4.2 0.4 0.7 0.3 0.4 0.5 0.3 0.2 0.1 0.1 1.2 7.8 0.9 0.0 0.1 0.2 0.2 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.4 0.2 0.7 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.1 1.4 0.1 0.4 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.4 0.2 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.2 1.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.6 0.1 0.0 0.1 0.1 0.0 0.6 0.6 2.4 1.0 0.6 0.5 0.8 0.5 0.9 0.4 0.5 0.9 100.0 3.2 6.4 1.6 0.0 2.5 22.6 0.3 0.0 0.2 0.2 0.3 0.3 4.3 42.9 1.8 0.0 0.1 0.4 1.0 0.0 0.1 2.7 0.4 0.5 2.4 1.8 5.3 3.7 0.4 0.3 0.8 0.0 0.1 0.0 0.2 1.8 131.3 0.2 0.0 3.0 0.5 0.0 2.4 0.4 2.7 0.0 0.7 0.0 0.0 0.3 0.3 0.0 1.5 2.8 0.1 1.4 0.4 0.1 4.7 0.2 0.5 34.0 0.1 0.0 0.7 0.4 0.0 0.9 0.2 0.4 0.0 0.7 0.2 0.7 57.0 HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 429.0;liver: 217.9;placenta: 381.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 155.8;Distal enterocytes: 203.4;Hepatocytes: 121.9;Paneth cells: 284.2;Proximal enterocytes: 390.7" "Group enriched" "Detected in many" 4 "liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 57.9;Hep G2: 47.5;hTERT-HME1: 27.1;OE19: 87.1;RT4: 96.8;TIME: 54.0" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: AB_2681059" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.83e-4)" 1.6 0.0 0.4 4.2 0.2 0.7 26.4 0.9 0.4 4.3 0.2 74.8 429.0 1.2 0.1 9.6 0.1 21.1 0.2 0.3 0.2 9.6 217.9 2.3 0.3 0.1 0.0 0.3 23.2 0.0 1.2 381.8 0.1 2.0 56.9 17.4 22.1 0.2 0.1 4.2 188.6 2.4 0.0 0.2 20.1 0.3 0.1 0.4 0.1 0.0 3.4 78.6 1.4 0.3 0.4 0.1 0.4 0.0 0.0 0.7 0.7 0.2 57.9 0.0 0.0 10.9 1.7 0.1 11.4 0.0 0.1 0.4 0.0 2.4 0.0 0.1 0.1 0.3 0.3 47.5 0.4 0.3 0.3 0.0 3.1 0.0 27.1 0.6 0.9 0.1 0.1 0.4 8.6 0.1 0.0 0.9 0.2 87.1 21.4 0.1 0.2 1.3 1.0 96.8 0.4 1.5 0.0 2.7 0.2 0.0 0.1 0.1 54.0 0.6 0.5 0.3 0.0 0.2 0.2 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.9 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.3 1.0 3.2 3.9 0.3 0.7 0.4 2.7 16.4 2.2 0.5 45.7 12.3 0.6 155.8 21.4 0.0 0.0 2.7 0.3 203.4 0.0 73.6 0.5 5.9 5.4 21.3 3.0 2.7 0.1 6.0 1.8 38.3 15.3 41.3 0.0 0.0 2.5 121.9 3.5 0.0 0.1 26.3 6.1 3.1 0.0 0.9 0.0 0.4 1.8 0.0 0.0 45.1 0.0 0.0 0.1 20.1 284.2 0.0 0.1 2.7 390.7 1.4 5.6 0.7 0.0 0.4 2.0 0.0 0.1 0.8 1.1 6.4 0.7 0.0 47.1 14.8 HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 65.0;Endothelial cells: 50.1;Hepatic stellate cells: 16.1;Late spermatids: 16.8;Microglial cells: 15.0;Peritubular cells: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.9;EFO-21: 4.9;HUVEC TERT2: 9.5;TIME: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" 23.1 4.1 9.3 3.0 8.9 1.3 23.0 6.6 7.8 15.0 4.2 6.6 1.8 12.5 1.2 4.2 10.3 4.7 29.3 6.6 7.0 11.8 1.7 20.6 1.7 8.2 7.9 8.2 2.6 1.5 2.9 11.3 8.4 4.9 1.2 0.4 5.4 1.9 12.3 7.7 6.1 4.0 6.8 25.3 5.1 5.2 10.4 0.7 9.2 10.2 0.9 10.2 10.2 6.0 0.5 1.7 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.2 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 1.4 9.5 0.4 0.3 0.2 0.0 1.0 0.4 0.9 1.0 0.0 0.8 1.8 0.2 0.5 0.0 0.0 0.9 0.7 0.3 0.2 0.1 0.1 0.2 0.5 5.3 0.1 2.2 0.7 0.4 0.4 0.3 0.5 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 9.3 8.9 6.6 7.8 6.6 7.0 8.2 7.9 8.4 6.8 10.4 6.0 65.0 0.0 0.0 0.3 0.4 1.9 0.1 0.0 0.0 0.5 0.7 0.3 5.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.8 0.2 3.2 50.1 0.0 0.0 0.5 0.0 0.2 10.5 0.0 0.1 0.0 0.1 16.1 0.3 0.5 0.0 0.4 0.0 0.0 1.4 2.5 16.8 7.5 0.2 0.0 15.0 0.0 3.1 0.0 0.0 0.3 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.2 2.0 3.5 1.7 0.3 1.1 0.4 0.3 0.7 0.0 0.2 HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 4135.3;skeletal muscle: 2417.8;tongue: 1229.5" "Cell type enriched" "Detected in some" 32 "Cardiomyocytes: 2389.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "fHDF/TERT166: 315.1" "Not detected" "Not detected" HPA027639 Approved Approved Nucleoplasm NA NA 130000 "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA027639: AB_10601756" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.28e-3)" "unprognostic (7.44e-3)" "unprognostic (8.35e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (1.02e-1)" "unprognostic (5.32e-2)" "unprognostic (2.47e-3)" "unprognostic (3.19e-3)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (1.26e-4)" 306.8 123.4 3.9 32.1 4.4 0.2 119.7 8.8 5.1 49.6 8.6 138.3 5.1 179.5 7.5 44.2 64.8 18.7 4135.3 4.1 5.6 38.5 3.2 22.1 1.7 13.1 7.9 25.4 9.2 38.8 5.3 7.1 12.0 43.0 8.0 3.1 35.1 24.4 2417.8 19.3 34.0 189.2 5.3 4.5 71.4 20.2 4.7 0.6 14.1 1229.5 0.7 99.2 30.5 6.7 0.0 0.0 0.0 1.5 70.7 3.2 1.8 18.4 1.1 0.0 0.2 0.0 0.1 0.0 0.0 315.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 3.4 0.0 0.0 2.1 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.6 0.1 0.1 0.0 0.1 5.3 3.3 0.0 0.0 0.0 1.3 0.0 11.8 0.0 1.3 0.1 1.1 0.0 14.1 0.6 1.9 0.0 10.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.4 8.8 5.1 4.1 5.6 13.1 7.9 12.0 5.3 4.7 6.7 0.5 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.8 0.2 0.4 2389.7 0.0 0.0 3.7 0.0 2.8 0.0 0.0 13.7 1.4 55.5 0.1 0.7 26.6 0.0 0.0 0.0 0.2 1.4 46.3 0.0 0.1 0.0 0.4 0.0 0.0 1.6 1.7 0.1 0.0 0.0 0.0 4.6 74.2 14.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.2 0.0 0.0 6.8 0.0 0.5 0.0 0.2 0.0 0.6 0.0 20.2 42.6 1.9 0.9 0.1 2.6 3.3 0.5 3.0 0.0 0.1 HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 897.3" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 599.1;Syncytiotrophoblasts: 1340.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 89.6;HeLa: 66.0;MCF7: 130.5;U-87 MG: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Nucleoplasm "HPA015876: AB_1850458" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.47e-1)" "unprognostic (4.03e-2)" "unprognostic (7.91e-2)" "unprognostic (6.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.36e-2)" "unprognostic (2.17e-2)" 57.0 13.9 172.2 34.4 172.6 0.0 33.4 179.5 141.8 58.1 147.0 381.0 8.9 114.4 10.1 163.2 58.7 43.1 469.3 147.8 231.0 63.3 4.8 95.7 11.4 188.3 206.1 23.4 30.8 183.1 17.5 92.1 193.0 143.5 35.8 28.2 50.8 289.0 897.3 70.5 50.5 114.1 211.5 56.2 110.4 12.0 193.6 40.3 29.2 448.5 98.7 239.2 100.1 235.5 21.1 16.1 0.3 0.0 14.4 11.5 60.2 32.5 28.7 5.9 0.3 40.0 0.6 0.1 89.6 42.4 48.0 2.4 0.3 0.0 0.6 0.1 1.2 0.0 66.0 3.2 11.2 0.0 0.1 14.1 4.1 22.3 1.3 21.6 12.3 0.0 0.2 0.0 13.0 130.5 0.0 0.2 5.7 0.0 23.0 0.0 22.9 2.9 38.3 6.2 0.4 1.0 13.5 1.6 6.8 50.5 29.0 0.2 20.4 15.8 39.8 21.7 1.7 0.0 0.2 0.2 67.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.2 172.6 179.5 141.8 147.8 231.0 188.3 206.1 193.0 211.5 193.6 235.5 2.7 44.8 48.2 42.1 0.7 102.3 108.5 4.5 126.3 0.7 95.2 17.5 599.1 7.2 5.4 5.5 8.4 149.1 1.0 0.0 0.0 59.7 12.2 98.1 20.2 27.4 0.0 0.0 6.2 11.4 17.5 82.2 5.6 142.7 1.3 0.0 25.4 0.0 19.4 1.7 6.6 0.0 2.0 1.0 9.4 11.0 1.5 1.6 12.4 2.8 1.0 51.7 0.0 0.0 0.9 12.9 0.0 0.4 0.3 24.6 0.0 52.0 3.1 2.1 6.6 39.8 76.9 0.9 0.2 38.0 28.7 1340.0 3.5 0.1 0.2 72.7 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;choroid plexus: 5.6" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;ASC TERT1: 4.6;BEWO: 1.4;HEL: 1.5;U-138 MG: 2.3;U-2 OS: 1.4;U-87 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" 0.9 0.3 6.7 0.8 9.7 0.1 0.5 0.0 15.2 0.6 5.6 0.5 0.4 0.5 0.0 0.5 0.3 1.6 0.7 11.8 8.7 0.1 0.1 0.3 0.0 0.5 1.4 0.3 0.0 0.0 0.2 0.0 2.9 0.2 0.6 0.8 0.0 0.6 0.3 0.1 0.4 2.6 0.1 0.0 0.2 0.6 1.6 0.7 0.1 0.6 0.2 0.8 0.5 5.8 0.0 0.0 0.0 0.0 1.8 4.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.7 9.7 0.0 15.2 11.8 8.7 0.5 1.4 2.9 0.1 1.6 5.8 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 8.6 0.1 0.0 0.0 81.7 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.0 10.1 0.0 0.0 0.3 0.0 2.2 0.9 1.9 0.0 3.7 0.0 4.6 0.0 2.5 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 1.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 178.4;Early spermatids: 87.3;Hofbauer cells: 57.0;Late spermatids: 76.4;Spermatocytes: 117.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NB-4: 286.4;U-698: 90.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" 8.2 5.1 23.4 32.0 34.7 6.9 5.2 24.3 21.1 9.3 162.1 6.5 4.8 10.1 11.5 4.6 9.2 8.3 17.5 26.2 29.5 3.3 4.4 13.7 65.0 25.7 32.8 13.5 1.7 2.2 3.0 8.1 27.8 6.4 6.7 2.7 3.9 8.7 7.9 3.0 17.8 10.3 20.2 42.7 7.6 44.7 27.6 16.2 3.9 9.8 72.9 9.7 5.2 25.0 0.1 0.5 2.8 0.2 4.5 4.7 1.4 0.9 1.1 2.6 1.4 0.5 0.0 2.9 2.4 5.1 0.0 0.4 3.3 0.2 3.7 0.2 0.6 0.1 0.3 0.7 4.0 44.1 3.1 6.2 0.4 2.4 0.0 0.4 6.4 13.4 1.9 2.4 4.7 0.2 6.4 286.4 3.2 0.0 2.7 5.4 0.2 0.3 0.0 0.1 0.3 0.4 0.1 0.0 0.2 2.9 0.0 42.8 1.9 0.0 0.2 0.4 0.1 27.4 3.7 90.5 0.3 2.2 0.2 378.0 208.3 675.7 14.0 197.8 7.7 550.4 13.2 22.7 88.7 799.8 25.2 17.2 327.4 182.6 185.0 131.7 31.0 193.2 23.4 34.7 24.3 21.1 26.2 29.5 25.7 32.8 27.8 20.2 27.6 25.0 18.4 3.2 5.3 9.4 178.4 0.8 1.9 2.0 1.2 0.5 1.2 2.8 6.6 0.0 3.6 1.8 0.0 0.4 25.8 0.0 0.0 0.5 87.3 0.5 5.8 13.1 0.0 0.8 0.6 0.2 1.4 5.4 1.5 0.3 8.2 3.9 12.1 0.3 57.0 0.0 0.5 0.2 0.0 41.7 17.2 76.4 13.4 42.2 12.4 15.0 31.6 15.2 23.7 2.0 0.1 0.5 0.1 13.9 9.9 0.6 0.0 0.5 1.7 1.8 13.1 4.7 15.1 117.5 2.8 0.7 0.4 1.2 7.6 0.5 0.2 1.2 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in many" 5 "Adipocytes: 497.6;Endothelial cells: 216.3;Hepatic stellate cells: 253.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 363.3;TIME: 502.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 97.4 62.6 24.7 29.1 23.0 3.1 93.9 24.9 28.3 51.6 24.3 34.0 17.9 66.1 10.3 39.7 55.6 47.5 92.2 22.3 24.8 85.1 32.2 186.8 40.0 26.0 24.9 29.1 27.9 25.7 41.6 87.4 27.5 37.2 11.5 3.3 37.5 22.0 30.9 37.1 38.7 37.4 27.1 282.8 38.6 22.0 28.1 9.5 80.9 35.7 14.6 47.0 45.8 24.9 26.8 38.5 63.0 64.1 38.2 32.9 39.6 29.8 41.2 42.0 32.6 44.6 77.3 7.0 102.4 43.6 82.5 27.4 24.6 58.7 12.0 14.2 19.6 9.7 34.9 69.2 33.0 8.1 24.4 51.9 48.8 42.1 13.8 38.1 363.3 18.2 17.6 8.0 35.4 37.0 17.7 16.6 72.0 23.2 55.7 15.5 12.4 26.1 52.4 24.2 16.6 53.3 30.4 31.2 31.8 21.2 34.4 20.3 502.9 50.0 49.7 33.5 47.5 13.9 24.1 21.6 29.4 25.5 73.0 0.0 9.5 10.7 1.4 14.1 3.0 1.1 1.3 3.8 5.3 1.5 0.4 0.7 9.2 2.8 13.6 4.0 1.9 3.3 24.7 23.0 24.9 28.3 22.3 24.8 26.0 24.9 27.5 27.1 28.1 24.9 497.6 19.2 9.9 5.2 3.6 13.0 28.6 45.2 11.4 7.8 17.6 16.6 7.3 32.9 30.9 33.1 6.2 33.6 4.1 13.5 11.7 53.0 4.7 8.5 19.8 216.3 7.3 10.1 1.6 38.7 38.4 26.6 16.8 13.8 0.0 31.5 253.1 9.1 46.2 8.4 1.9 13.0 42.7 12.6 9.3 5.0 24.5 9.4 17.8 15.9 7.6 19.7 5.2 4.0 3.4 45.6 13.5 22.2 4.2 45.3 16.1 11.8 11.0 6.1 39.5 11.2 26.0 11.2 56.0 24.9 12.6 32.7 4.1 50.0 16.6 33.3 ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 594.7;Late spermatids: 867.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 29.9" "Lineage enriched" "Detected in many" 9 "T-cells: 29.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.1;MCF7: 42.5;OE19: 48.4;RT4: 49.4;SCLC-21H: 66.1;SH-SY5Y: 105.8;SK-BR-3: 52.1;T-47d: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: AB_2684525" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" 15.8 10.4 11.3 5.7 16.2 23.8 21.1 21.5 21.8 16.4 1.2 22.8 13.6 6.8 13.6 9.5 13.7 11.1 44.3 13.4 9.3 16.0 8.8 11.2 13.5 8.0 9.5 1.7 62.7 20.9 19.8 8.2 9.3 22.1 23.5 2.9 37.1 4.9 2.8 12.8 17.8 5.6 5.1 12.4 30.5 24.2 13.3 5.0 14.1 3.3 9.6 13.8 7.4 15.3 0.0 1.5 1.7 0.2 0.2 0.0 4.2 0.0 0.0 0.6 0.2 1.0 47.1 0.3 5.2 0.1 0.9 0.0 0.8 1.9 0.0 0.0 6.8 9.1 0.9 0.0 0.4 9.1 1.8 0.0 3.0 0.0 0.0 0.5 31.5 8.2 26.4 0.0 0.0 42.5 0.4 0.0 9.9 48.4 0.4 0.0 0.0 19.5 19.0 49.4 66.1 105.8 0.0 52.1 0.7 11.6 43.4 14.3 19.8 0.0 0.9 0.2 1.0 14.1 7.5 0.0 0.0 6.9 10.3 1.0 2.4 0.2 0.3 0.8 0.6 0.4 5.4 0.4 2.4 0.7 0.3 0.2 3.4 0.9 0.4 0.6 29.9 1.3 11.3 16.2 21.5 21.8 13.4 9.3 8.0 9.5 9.3 5.1 13.3 15.3 73.4 28.9 24.4 6.5 1.6 20.5 16.2 7.1 9.1 10.4 42.8 28.7 43.2 22.8 20.1 22.0 6.2 2.7 2.1 28.2 43.0 38.4 594.7 34.2 5.8 44.1 77.2 16.4 132.1 74.8 0.8 4.5 56.1 65.4 8.2 11.2 42.1 1.3 23.9 0.0 138.0 80.5 44.7 8.1 9.3 867.0 7.5 9.6 14.2 60.0 6.3 0.8 3.1 49.3 3.9 59.8 53.1 3.0 1.7 53.8 23.8 8.3 17.8 1.7 6.6 1.2 5.6 13.9 9.6 18.4 8.9 2.2 9.5 4.7 41.8 42.7 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 151.9;dendritic cells: 164.6;Hepatocytes: 168.8;NK-cells: 313.1;Plasma cells: 137.2;T-cells: 183.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Cell line enhanced" "Detected in many" "Karpas-707: 324.6;NB-4: 222.3;RPMI-8226: 257.6;U-266/84: 188.8;U-937: 179.0" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" 18.9 7.4 4.8 50.4 4.6 206.5 10.0 4.5 6.4 4.9 4.4 16.1 15.1 3.6 2.8 7.6 6.2 9.0 18.1 4.5 4.6 11.9 73.2 16.0 72.2 4.9 5.0 2.9 15.2 2.9 1.0 4.6 5.0 6.8 11.0 0.9 15.2 2.9 18.0 4.3 28.1 4.4 5.2 85.8 19.5 2.1 5.2 48.6 6.8 11.9 50.6 14.1 4.4 4.6 12.4 5.8 4.2 13.1 6.8 5.3 7.3 7.5 5.1 5.9 5.2 5.3 8.1 0.2 24.9 6.2 0.1 5.4 0.2 5.5 2.0 106.2 3.7 23.8 5.4 22.6 3.4 96.7 102.1 4.8 4.4 7.0 2.6 6.4 2.9 57.1 13.0 324.6 6.9 24.0 13.9 222.3 3.2 31.7 38.3 11.1 2.7 257.6 6.2 11.2 1.3 5.6 6.5 20.4 17.3 1.9 17.7 23.9 4.6 28.0 3.0 31.2 7.6 20.7 188.8 37.3 20.2 179.0 22.1 193.6 395.4 872.4 362.7 287.8 436.2 280.1 343.0 331.7 327.5 271.7 301.5 283.9 1948.5 380.1 417.4 52.9 436.3 614.5 4.8 4.6 4.5 6.4 4.5 4.6 4.9 5.0 5.0 5.2 5.2 4.6 22.6 3.2 29.7 0.7 151.9 8.2 6.5 7.0 10.2 0.3 23.1 20.6 0.1 21.5 9.8 5.5 0.0 12.0 164.6 49.1 62.6 16.9 7.7 10.7 9.4 19.2 5.4 37.4 0.2 35.4 24.7 10.2 16.8 9.9 30.4 5.5 31.1 168.8 24.0 1.7 0.1 33.2 4.1 70.0 50.4 10.0 6.2 52.9 55.2 1.0 127.7 6.4 313.1 0.0 0.1 23.2 43.8 4.1 137.2 12.3 79.9 54.4 9.0 1.2 0.0 7.3 10.7 5.7 0.7 8.3 8.4 4.7 183.3 5.4 36.4 10.2 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 323.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "amygdala: 194.3;basal ganglia: 212.9;cerebral cortex: 323.4;hippocampal formation: 320.5;white matter: 109.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 24: Non-specific - Transcription regulation" "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 32.7 43.3 194.3 29.5 212.9 47.6 27.9 0.0 323.4 37.5 0.0 35.7 21.1 35.1 43.5 26.1 35.7 26.3 42.2 320.5 25.7 22.7 15.8 40.5 31.0 9.7 9.4 45.4 23.3 57.0 67.8 16.3 3.1 29.4 20.8 48.6 24.7 41.0 25.1 37.1 27.9 30.5 0.2 34.1 23.0 6.1 32.3 17.2 27.2 38.9 36.0 32.8 31.5 109.4 46.4 50.7 19.6 12.7 22.1 40.9 9.2 26.6 67.8 23.3 43.9 10.2 32.7 110.0 69.6 38.3 49.1 22.6 21.3 40.5 30.1 40.8 17.7 11.5 14.7 5.7 17.8 18.8 101.3 21.4 19.6 50.9 33.1 95.5 37.8 20.2 5.7 76.6 34.7 57.9 19.6 9.3 17.5 28.8 34.3 12.4 19.4 20.7 27.8 10.5 28.9 67.6 9.8 22.1 32.0 33.2 6.9 7.9 44.3 29.9 31.3 50.1 70.8 54.5 47.3 79.3 138.0 44.3 22.1 117.5 56.9 171.7 70.9 63.0 53.2 35.2 43.1 54.0 48.7 27.0 28.4 42.9 261.1 37.2 73.9 36.8 74.0 63.0 194.3 212.9 0.0 323.4 320.5 25.7 9.7 9.4 3.1 0.2 32.3 109.4 53.7 99.3 64.4 55.8 150.9 33.1 60.6 44.0 20.5 178.3 43.2 43.8 44.1 27.1 58.9 82.8 45.9 34.2 158.5 66.9 21.5 50.2 1.3 59.8 36.8 44.7 168.4 19.6 232.3 74.0 25.7 78.3 31.1 49.5 226.2 25.5 60.3 33.0 44.0 222.1 243.7 29.0 73.2 94.8 109.8 3.7 72.7 98.4 51.6 63.7 120.9 55.0 146.2 39.2 95.8 85.0 50.3 89.5 98.8 71.3 74.6 22.3 112.4 59.5 59.2 68.1 65.2 3.5 6.6 22.2 43.8 143.0 183.9 16.4 17.1 96.9 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 IFITM10 DSPA3 ENSG00000244242 "Interferon induced transmembrane protein 10" A6NMD0 11 1732406-1750595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 2.6;bone marrow: 1.5;brain: 3.2;choroid plexus: 1.8;retina: 1.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 46.0;Bipolar cells: 30.5;granulocytes: 28.5;Hepatic stellate cells: 40.0;Oligodendrocyte precursor cells: 39.7;Respiratory ciliated cells: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.9;hTERT-RPE1: 4.7;MCF7: 4.4;SH-SY5Y: 11.2;SK-MEL-30: 4.0;U-87 MG: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.89e-3)" "unprognostic (2.10e-2)" "unprognostic (1.22e-6)" "unprognostic (6.49e-3)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" "unprognostic (3.66e-1)" "unprognostic (4.09e-1)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-1)" "unprognostic (2.44e-2)" "unprognostic (3.76e-2)" 0.1 2.6 2.1 0.1 2.1 1.5 0.0 3.2 3.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.2 2.4 0.1 0.3 0.2 0.0 2.3 2.2 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 1.5 0.3 0.5 0.2 0.4 0.1 0.0 2.1 0.1 0.0 0.3 2.3 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.2 4.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 11.2 0.0 0.0 4.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.1 3.2 3.0 2.2 2.4 2.3 2.2 2.4 2.1 2.3 2.2 0.3 3.2 0.6 1.0 1.3 2.2 9.3 46.0 14.2 30.5 0.8 1.7 1.9 1.5 16.4 0.0 0.0 1.8 0.4 8.1 1.9 3.9 0.4 1.2 0.5 1.0 0.0 0.0 10.5 2.6 0.6 5.4 1.1 2.7 28.5 0.0 40.0 1.6 20.6 1.7 11.4 0.9 18.3 5.0 1.1 0.6 0.9 9.3 0.0 1.9 2.6 2.1 3.1 39.7 1.0 2.3 4.2 1.5 1.3 1.3 3.3 0.1 49.4 2.3 0.0 2.4 4.0 0.5 1.3 3.2 0.9 2.6 2.5 0.1 1.9 12.7 IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 23.5 15.1 12.2 11.7 12.6 29.1 26.1 12.4 15.2 29.3 14.3 16.3 9.2 27.4 29.0 14.8 38.0 19.0 11.8 12.5 13.5 20.5 7.8 16.9 18.3 12.3 12.8 39.2 15.7 22.5 16.5 17.5 12.8 17.5 17.8 15.1 13.6 23.8 4.7 15.5 11.2 24.3 13.3 15.7 12.2 31.8 14.1 22.8 31.3 9.0 18.9 19.5 18.0 14.2 33.9 25.4 50.3 35.8 41.9 46.4 23.9 20.8 46.1 53.6 51.6 70.5 33.7 18.8 32.8 42.6 43.4 27.7 21.3 37.3 58.6 15.6 20.0 24.8 16.2 65.9 51.4 33.4 16.4 37.8 40.2 34.9 27.0 39.0 42.7 41.4 21.3 26.1 39.9 34.0 46.4 51.5 28.4 22.2 24.9 48.6 57.5 27.8 41.8 32.9 38.8 45.3 63.6 46.7 52.2 25.3 21.8 45.1 26.9 47.3 35.1 26.3 31.1 25.3 26.9 32.8 56.8 24.0 34.8 8.0 22.0 16.8 18.4 20.9 15.0 17.5 14.7 17.5 28.4 15.3 15.4 16.0 6.3 17.4 26.2 21.5 18.6 17.3 12.2 12.6 12.4 15.2 12.5 13.5 12.3 12.8 12.8 13.3 14.1 14.2 21.1 6.4 13.1 11.4 13.7 13.0 12.8 22.4 12.0 11.5 14.1 19.2 2.9 11.5 13.2 7.3 0.0 19.9 16.0 14.8 19.6 26.1 78.4 32.1 19.4 18.1 9.5 23.4 20.5 22.2 19.7 25.3 8.2 10.5 14.5 26.7 23.2 2.6 19.4 8.4 22.5 11.0 14.2 18.2 13.9 20.9 28.6 13.3 17.8 12.2 21.3 22.6 18.6 14.6 25.7 14.8 10.1 38.4 13.5 5.9 5.5 18.3 49.0 12.8 13.1 23.9 24.8 57.3 18.5 12.2 14.9 9.6 12.1 30.4 10.3 10.5 IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 18.6;Cone photoreceptor cells: 31.3;Fibroblasts: 14.7;Leydig cells: 34.8;Microglial cells: 14.0;Oligodendrocyte precursor cells: 17.6;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.4;AF22: 9.4;CAPAN-2: 8.1;EFO-21: 4.5;HSkMC: 5.2;NTERA-2: 7.2;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" 0.9 2.5 5.6 2.4 6.9 0.0 0.5 5.8 2.5 3.4 0.0 0.8 0.5 1.4 4.2 1.6 1.7 4.2 0.9 2.9 7.2 0.1 0.0 0.2 0.6 11.2 9.4 8.5 0.1 0.3 0.9 5.6 6.8 0.4 0.6 0.8 0.5 0.4 10.6 0.8 0.8 1.0 6.9 0.2 1.1 0.6 11.3 0.7 1.9 14.0 0.6 2.1 2.0 4.5 0.0 4.4 9.4 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.5 8.1 0.0 4.5 0.3 0.0 0.0 2.3 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.0 0.0 5.2 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.8 7.2 0.0 0.0 0.0 2.3 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.4 5.4 0.0 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 6.9 5.8 2.5 2.9 7.2 11.2 9.4 6.8 6.9 11.3 4.5 0.2 0.0 0.0 18.6 0.0 2.3 0.0 0.0 0.0 7.7 0.2 0.5 2.2 0.0 0.0 3.7 31.3 0.4 0.1 0.0 0.0 0.4 0.4 0.0 2.1 0.3 0.0 0.0 0.9 0.0 0.6 14.7 1.1 0.0 0.0 8.8 0.0 0.0 0.7 0.0 6.3 0.0 0.0 0.0 2.5 1.4 34.8 0.3 5.4 14.0 0.0 1.0 1.0 17.6 1.0 0.3 0.0 4.1 0.1 0.1 0.0 0.7 0.0 12.2 6.6 29.8 1.0 0.8 2.6 0.1 1.1 0.8 0.3 7.0 0.0 0.0 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHD3-10 "DXP'1, IGHD310" ENSG00000211923 "Immunoglobulin heavy diversity 3-10" 14 105904497-105904527 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 1.3;intestine: 3.7;lymphoid tissue: 4.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "naive B-cell: 5.4" "Lineage enriched" "Detected in single" 55 "B-cells: 5.4" "Cell line enriched" "Detected in single" 12 "NB-4: 1.1" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 4.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-3 "DXP4, IGHD33" ENSG00000211930 "Immunoglobulin heavy diversity 3-3" 14 105914359-105914389 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.3;lymphoid tissue: 2.6;salivary gland: 3.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 62.6" "Lineage enriched" "Detected in single" 626 "B-cells: 62.6" "Group enriched" "Detected in some" 48 "NB-4: 6.9;SH-SY5Y: 2.6" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-1)" "unprognostic (1.75e-1)" 0.0 0.0 0.0 0.9 0.1 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.0 0.0 0.0 1.0 0.0 0.0 1.9 1.6 0.1 0.0 0.1 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 6 "Plasma cells: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Group enriched" "Detected in some" 25 "Daudi: 3.8;K-562: 1.1" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" 2.0 0.0 0.2 0.0 0.5 13.3 20.5 0.2 2.0 48.7 0.1 87.2 0.0 5.4 17.9 18.0 2.1 0.8 0.1 0.2 0.4 1.2 12.0 0.0 7.6 3.8 0.8 7.7 18.9 0.6 0.0 0.0 0.5 15.0 127.5 0.0 0.0 7.1 0.0 0.0 0.0 5.8 0.6 18.8 18.2 0.1 0.5 19.6 5.1 0.0 174.5 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 49.0 1.3 0.4 1.6 0.4 12.6 0.0 0.2 0.2 0.0 0.6 0.0 0.0 17.1 0.2 0.5 0.2 2.0 0.2 0.4 3.8 0.8 0.5 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Cell type enriched" "Detected in some" 226 "Plasma cells: 10423.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cell line enriched" "Detected in some" 6 "MOLT-4: 11.2" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 6.3 0.3 0.0 5.8 0.0 2.5 3.6 0.0 0.0 1.5 0.0 12.0 22.1 1.1 0.2 2.1 1.2 14.5 1.6 0.0 0.0 2.7 0.9 4.5 13.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 14.4 0.0 16.4 0.9 0.0 0.0 18.0 0.2 0.0 47.1 9.9 0.2 0.0 3.7 1.1 0.0 36.5 4.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 6.7 0.5 0.9 0.0 5.5 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 1.4 23.0 0.0 0.0 0.0 1.1 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10423.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 10 "B-cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Cell line enriched" "Detected in single" 7 "MOLT-4: 1.7" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" 1.7 0.7 0.0 16.6 0.0 4.1 7.1 0.0 0.0 5.6 0.1 36.8 14.2 1.9 0.0 5.2 4.5 20.9 1.7 0.0 0.0 2.5 2.3 6.2 4.6 0.0 0.0 0.8 0.3 0.1 0.1 0.0 0.0 0.7 33.1 0.0 30.3 0.1 0.0 0.1 21.7 0.6 0.0 41.4 47.0 0.0 0.0 4.5 2.5 0.0 90.8 3.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;lymphoid tissue: 32.1;salivary gland: 21.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Cell line enhanced" "Detected in single" "HL-60: 1.1" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" 1.7 0.1 0.0 2.0 0.0 8.6 7.2 0.0 0.4 0.7 0.0 17.9 6.9 0.9 0.0 1.2 1.9 4.1 1.2 0.0 0.0 0.8 2.2 4.3 0.0 0.1 0.0 3.3 3.6 0.0 0.1 0.0 0.0 0.5 1.2 0.0 21.0 0.4 0.0 0.1 11.3 1.3 0.0 32.1 6.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cell line enriched" "Detected in some" 818 "Daudi: 1604.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" 0.2 0.0 0.1 5.3 0.0 0.6 0.4 0.0 0.1 1.3 0.0 6.7 6.0 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 7.0 0.0 0.0 0.0 4.0 0.1 0.0 32.2 4.2 0.0 0.0 1.0 0.3 0.0 10.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1604.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 652 "Plasma cells: 65.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cell line enhanced" "Detected in some" "Daudi: 6.6;HBEC3-KT: 7.2;hTEC/SVTERT24-B: 4.1;REH: 4.1" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" 0.5 1.4 0.1 23.3 0.4 11.2 16.7 0.0 0.3 4.8 5.6 38.2 21.8 0.3 0.0 6.8 0.4 5.5 0.2 0.8 0.0 0.1 1.4 6.9 14.0 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.9 22.1 0.1 15.2 0.5 0.1 4.8 13.9 0.8 0.0 12.7 16.9 0.0 0.1 3.8 1.3 0.0 56.7 21.7 0.1 0.0 2.1 0.7 0.3 0.0 0.0 0.0 0.4 0.0 2.2 0.3 1.5 3.0 1.2 6.6 0.0 0.9 1.1 0.3 0.0 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 4.1 2.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.6 0.4 0.0 1.6 4.1 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.6 0.0 1.3 0.2 0.2 0.1 1.2 0.1 0.4 0.4 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 13.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.1 0.4 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Cell line enhanced" "Detected in single" "Daudi: 1.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" 0.4 0.1 0.0 9.3 0.0 1.1 6.7 0.0 0.1 10.2 0.0 9.7 42.8 0.9 0.0 10.5 15.5 0.1 0.1 0.0 0.0 0.3 1.4 10.9 0.9 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 7.1 0.0 5.9 2.0 0.0 0.1 6.2 0.0 0.0 17.8 19.6 0.2 0.0 1.9 1.2 0.1 6.2 34.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 489 "Plasma cells: 1517.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cell line enhanced" "Detected in single" "Daudi: 3.7" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" 1.7 1.4 0.0 21.0 0.0 14.8 13.5 0.0 0.1 10.0 0.0 16.6 6.9 3.0 0.0 35.6 14.4 7.7 2.0 0.0 0.0 1.0 2.9 19.5 65.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.6 21.8 0.0 32.3 21.7 0.0 0.0 31.2 1.6 0.0 44.8 38.6 0.4 0.0 26.3 5.7 0.0 123.3 34.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 134.9 0.0 0.0 0.0 96.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1517.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745407-39802096 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 114.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 5.8" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" 0.3 1.2 2.0 0.2 2.8 0.4 0.9 0.6 1.9 0.7 2.4 0.4 0.3 0.7 1.9 0.2 0.7 0.4 3.3 1.5 2.6 0.4 0.4 0.3 0.4 1.5 1.6 1.0 1.5 0.2 0.6 2.5 1.3 1.4 0.7 1.2 0.5 0.4 0.2 0.5 0.3 0.4 0.7 0.4 0.5 1.1 3.6 0.6 0.6 0.1 0.4 0.4 0.1 1.4 0.7 0.4 2.4 0.6 2.3 1.8 0.6 0.4 0.6 0.6 1.0 0.4 0.7 0.8 0.6 0.9 0.9 0.6 0.8 1.6 1.3 1.3 1.1 0.7 1.9 0.3 1.4 1.0 0.3 1.7 2.9 1.5 1.7 1.2 0.3 0.3 1.4 0.5 0.9 0.9 0.2 0.3 1.3 0.6 0.4 0.4 1.1 0.4 1.0 1.0 1.1 0.3 0.6 1.6 1.0 1.0 5.8 0.6 0.2 1.0 1.2 0.5 1.0 0.5 0.4 0.5 0.6 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 2.8 0.6 1.9 1.5 2.6 1.5 1.6 1.3 0.7 3.6 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.2 0.0 0.0 1.2 1.0 0.8 9.7 0.0 0.1 1.8 0.0 1.6 0.0 0.6 5.9 0.6 12.8 0.0 0.4 0.2 0.0 0.0 2.9 0.2 1.7 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.1 0.4 0.0 0.0 0.0 4.8 0.3 0.1 0.0 0.0 0.0 1.0 0.0 5.0 1.0 0.2 0.2 0.4 0.0 1.4 0.0 6.8 0.1 0.2 0.0 0.0 0.2 0.5 0.2 0.0 0.0 114.1 0.1 1.1 0.4 2.0 IGSF9B "KIAA1030, LINC00947, LOC283174, MIR4697HG" ENSG00000080854 "Immunoglobulin superfamily member 9B" Q9UPX0 11 133896438-133956968 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8;choroid plexus: 20.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 25.2;Inhibitory neurons: 11.6;Oligodendrocyte precursor cells: 30.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 10.0;SCLC-21H: 17.7;SH-SY5Y: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010802 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cell Junctions" "HPA010802: AB_1079194" "unprognostic (9.04e-4)" "unprognostic (1.74e-2)" "unprognostic (7.52e-3)" "unprognostic (4.38e-4)" "unprognostic (8.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.17e-2)" "unprognostic (1.38e-1)" "unprognostic (8.10e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-4)" "unprognostic (3.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (9.14e-4)" "unprognostic (3.12e-3)" 1.0 1.4 9.4 1.4 3.8 0.2 0.8 38.8 30.7 2.2 20.2 4.7 0.5 4.8 3.0 2.8 4.6 1.2 6.7 8.3 0.0 0.4 0.0 0.8 0.7 0.0 0.9 1.0 0.9 0.7 2.6 0.6 1.1 2.6 1.3 9.3 0.8 4.1 4.7 2.3 1.3 4.5 0.0 0.9 1.9 3.3 0.0 0.5 2.5 3.5 0.7 2.6 1.6 0.0 0.0 0.6 1.2 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.1 2.6 1.6 0.7 0.6 0.3 3.7 3.9 0.0 0.1 2.8 3.1 0.0 0.0 0.0 0.1 1.0 5.1 0.1 0.0 0.0 0.5 0.5 0.0 4.7 0.0 0.0 0.0 1.9 0.5 0.4 2.5 10.0 0.0 0.0 0.0 0.0 0.9 0.0 17.7 11.1 0.1 0.2 0.0 3.7 1.8 0.0 0.0 1.2 1.3 1.0 0.9 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 3.8 38.8 30.7 8.3 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 3.4 0.1 0.2 0.0 2.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.4 0.0 0.0 0.9 0.0 0.0 25.2 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 30.7 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.0 0.9 0.0 0.2 0.6 0.0 0.3 0.1 4.8 0.0 0.6 0.1 0.2 0.1 IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.5;Enteroendocrine cells: 49.2;Granulosa cells: 122.4;Intestinal goblet cells: 34.7;Proximal enterocytes: 18.8;Undifferentiated cells: 23.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 16.4;OE19: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.1 2.4 4.9 0.0 22.3 12.2 14.0 0.0 0.3 0.9 0.7 0.0 0.0 0.0 2.4 3.5 1.3 0.0 0.3 0.1 0.4 0.0 0.0 0.5 0.1 0.4 2.4 12.4 0.0 0.0 0.7 0.0 0.0 12.9 0.7 0.2 0.0 15.0 0.1 0.1 0.0 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.4 31.5 0.0 0.1 0.0 6.0 0.5 0.1 49.2 0.0 0.0 3.3 0.0 0.1 12.2 8.9 0.0 122.4 0.0 0.6 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 14.0 0.0 0.0 1.8 18.8 3.2 0.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 23.6 0.3 IKZF3 "Aiolos, ZNFN1A3" ENSG00000161405 "IKAROS family zinc finger 3" Q9UKT9 17 39757718-39864312 "Predicted intracellular proteins, Transcription factors" "B-cell activation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 12.1;lymphoid tissue: 41.0" "Group enriched" "Detected in many" 4 "B-cells: 108.1;dendritic cells: 76.5;granulocytes: 47.9;NK-cells: 121.5;Plasma cells: 80.2;T-cells: 99.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 13.2;T-cells: 28.8" "Cell line enhanced" "Detected in some" "Daudi: 69.0;Karpas-707: 35.6;U-266/70: 41.7;U-266/84: 50.0;U-698: 108.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA024377, HPA073266" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA024377: AB_1859477, HPA073266: " "unprognostic (5.43e-3)" "prognostic favorable (6.85e-6)" "unprognostic (6.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.93e-2)" "prognostic favorable (4.16e-4)" "unprognostic (1.36e-2)" "unprognostic (3.14e-3)" "prognostic favorable (5.42e-4)" "unprognostic (8.03e-3)" "unprognostic (1.65e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (9.13e-2)" "unprognostic (2.20e-1)" "unprognostic (5.51e-2)" "unprognostic (1.05e-3)" 1.0 0.8 0.3 18.8 0.2 5.9 1.8 0.7 0.6 1.5 0.6 3.3 3.5 1.0 0.7 1.5 0.7 3.0 0.5 0.7 0.1 0.6 2.0 3.1 36.5 0.5 0.1 0.7 0.4 0.1 0.2 0.3 0.4 1.0 3.1 0.3 2.2 0.3 0.5 0.9 12.1 0.8 0.1 22.3 6.2 1.6 0.4 23.0 0.9 0.3 41.0 4.5 0.7 1.0 0.2 0.2 0.2 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.3 69.0 0.1 0.0 0.1 0.3 0.1 0.2 0.0 15.6 0.3 4.2 0.4 0.2 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.0 4.1 1.8 35.6 0.0 0.2 6.2 2.4 0.2 3.9 0.1 0.3 0.2 12.7 0.0 4.2 0.4 0.2 1.2 0.5 0.1 0.1 0.2 0.8 0.3 0.3 0.5 0.2 0.1 41.7 50.0 108.1 0.1 0.2 0.1 1.0 0.2 0.8 26.3 0.1 28.8 13.2 11.0 20.3 0.1 11.9 4.5 12.2 1.1 4.5 0.3 0.6 18.9 8.7 0.3 0.2 0.7 0.6 0.7 0.1 0.5 0.1 0.4 0.1 0.4 1.0 1.1 9.6 21.8 0.3 108.1 0.1 2.2 0.0 0.0 1.7 1.2 0.9 4.0 1.5 5.6 1.8 0.0 0.1 76.5 0.2 0.0 0.1 12.8 1.9 0.9 2.4 0.0 4.0 0.6 0.0 0.4 2.3 3.1 3.9 47.9 0.4 4.2 1.2 0.1 0.0 0.4 0.1 0.0 6.3 0.0 11.8 0.0 4.4 0.0 2.8 3.3 0.2 121.5 0.0 0.1 1.2 0.1 0.0 80.2 1.8 0.0 0.3 0.7 1.7 0.0 4.0 1.2 6.3 2.3 0.6 0.1 0.3 99.9 0.1 0.0 1.6 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 44.8;Peritubular cells: 13.2;Sertoli cells: 26.3;Smooth muscle cells: 7.6;Theca cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.3;Karpas-707: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" 1.4 2.2 0.0 1.0 0.0 0.2 2.9 0.5 0.1 3.2 0.0 3.1 0.3 4.3 0.0 1.5 1.1 0.4 1.1 0.0 0.0 0.7 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 2.4 0.1 0.4 2.8 2.1 0.3 0.9 1.3 2.2 0.0 0.6 0.8 3.7 0.0 0.0 0.1 0.2 0.0 1.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.8 44.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.6 1.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 1.0 1.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 26.3 0.6 7.6 0.1 0.1 0.0 0.3 0.0 0.0 9.9 0.0 0.1 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 14.0;Early spermatids: 17.9;Late spermatids: 23.7;Microglial cells: 15.0;Peritubular cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 25.0;AN3-CA: 67.9;NTERA-2: 39.2;SH-SY5Y: 102.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" 1.9 0.8 4.7 0.9 5.7 0.0 7.4 5.2 4.0 6.0 28.0 5.9 0.4 13.5 10.6 2.4 6.4 3.3 1.9 5.5 6.5 5.7 0.2 0.6 0.3 8.9 8.8 7.4 0.9 9.4 2.3 0.3 5.5 5.1 1.8 0.3 6.0 8.5 0.6 2.0 1.0 12.0 6.2 2.5 1.2 9.7 4.8 0.3 0.5 2.6 0.5 2.8 3.3 6.5 4.0 0.8 25.0 67.9 0.1 0.6 4.0 0.4 0.2 0.3 0.8 0.5 1.9 0.0 0.2 1.4 5.3 0.2 4.8 1.0 0.8 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.1 1.0 2.6 0.0 0.5 16.6 1.1 0.6 0.0 0.1 1.4 0.5 0.0 0.1 39.2 2.2 1.9 0.0 9.1 0.0 5.2 1.0 0.6 102.0 1.0 1.5 2.9 8.1 0.9 0.0 0.7 1.3 1.6 1.2 4.2 0.0 0.0 0.1 0.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 5.7 5.2 4.0 5.5 6.5 8.9 8.8 5.5 6.2 4.8 6.5 1.4 0.0 2.3 11.4 0.0 0.9 2.0 3.1 0.0 0.1 1.5 14.0 1.6 1.5 2.4 0.0 0.0 0.3 0.1 0.1 0.0 3.1 17.9 0.5 5.5 4.0 0.0 0.0 0.6 0.2 0.1 10.1 0.0 1.0 0.0 2.0 1.1 0.1 0.1 0.0 0.9 0.3 2.0 0.0 1.2 23.7 11.5 0.6 0.0 15.0 0.0 0.6 0.0 7.5 2.1 0.7 0.7 25.9 0.0 2.9 0.0 5.0 1.8 0.0 0.0 4.8 1.3 10.6 7.5 1.1 0.9 0.1 0.3 6.5 0.3 0.7 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.8;Basal respiratory cells: 115.8;Basal squamous epithelial cells: 60.9;Club cells: 43.0;Early spermatids: 57.0;Late spermatids: 28.8;Squamous epithelial cells: 56.5;Suprabasal keratinocytes: 38.1" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 86.0;HBEC3-KT: 140.0;HHSteC: 91.8;hTCEpi: 555.6;hTERT-HME1: 102.6" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" 2.3 0.2 0.1 0.0 0.2 0.0 10.3 0.1 0.6 24.3 0.1 0.6 0.0 0.2 0.0 110.7 0.4 0.0 0.6 0.1 0.1 0.2 5.4 0.5 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.4 0.2 2.2 0.5 0.0 13.6 0.2 1.0 163.3 0.4 0.0 0.1 0.3 0.5 3.7 0.2 2.0 0.5 0.9 9.5 1.3 66.2 0.2 27.2 0.0 0.1 0.4 15.4 64.9 2.6 0.6 1.8 0.3 1.2 2.7 3.4 0.2 14.9 9.7 1.0 86.0 0.0 140.0 0.7 0.4 0.0 0.3 19.5 0.0 91.8 0.2 0.2 11.5 555.6 4.5 102.6 0.7 0.1 0.1 0.3 0.1 0.0 0.0 0.6 0.0 0.4 2.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 54.6 0.0 2.8 4.7 0.5 0.9 0.0 0.2 1.8 0.5 0.5 0.1 0.2 0.2 8.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.0 0.0 0.7 0.0 36.8 1.7 115.8 60.9 0.0 0.3 0.5 0.4 0.0 43.0 0.0 0.0 1.7 0.8 0.8 0.0 0.9 57.0 0.7 0.4 0.9 0.0 0.0 1.0 0.2 1.4 3.9 0.0 0.8 0.0 0.2 0.0 2.2 0.4 0.0 1.2 0.7 10.2 0.3 6.6 28.8 0.3 0.6 3.6 1.0 1.7 0.0 1.0 1.0 0.2 1.0 0.1 0.7 0.4 1.3 0.2 0.3 5.5 0.0 0.0 0.6 3.6 1.7 1.9 56.5 38.1 1.6 0.6 0.2 0.5 5.3 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Late spermatids: 1.2;Spermatocytes: 2.5;Syncytiotrophoblasts: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 26.3;HBEC3-KT: 10.3;HHSteC: 9.5;hTERT-HME1: 11.5;U-2 OS: 16.8;U-87 MG: 20.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.1 1.8 0.0 2.1 0.0 0.6 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.4 0.5 0.2 0.5 0.3 0.1 0.0 0.2 0.0 0.0 0.4 26.3 0.0 0.0 10.3 2.2 0.0 0.1 0.0 0.0 0.0 9.5 0.0 0.0 7.3 2.9 4.8 11.5 0.6 4.1 0.1 0.0 0.4 1.4 0.0 0.0 1.2 0.0 0.0 6.8 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 2.0 0.5 16.8 0.0 0.8 0.0 0.0 0.0 20.8 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.3 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 2.5 0.6 0.0 0.1 1.1 0.0 0.7 0.0 0.0 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 IL5RA "CD125, CDw125, IL5R" ENSG00000091181 "Interleukin 5 receptor subunit alpha" Q01344 3 3066324-3126613 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.0;fallopian tube: 10.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 28.0;granulocytes: 19.0;Plasma cells: 9.9;Respiratory ciliated cells: 13.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 192 "basophil: 178.4;eosinophil: 355.1" "Lineage enriched" "Detected in many" 255 "granulocytes: 355.1" "Cell line enriched" "Detected in some" 28 "HMC-1: 71.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 910000 "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.38e-3)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (6.13e-3)" "unprognostic (2.66e-1)" "unprognostic (1.54e-3)" "unprognostic (7.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.83e-1)" "unprognostic (1.67e-1)" "unprognostic (9.84e-4)" "unprognostic (4.32e-3)" "unprognostic (3.08e-2)" "unprognostic (6.95e-2)" "unprognostic (2.20e-1)" "unprognostic (7.49e-2)" "unprognostic (4.93e-2)" 0.2 0.2 0.8 0.6 0.7 0.6 1.0 0.6 0.3 1.0 9.0 0.7 1.7 0.4 0.2 0.5 10.7 0.7 1.0 0.8 1.2 0.4 0.1 2.7 0.4 5.0 4.6 0.1 0.4 0.0 1.5 0.1 3.2 1.8 1.1 0.0 0.7 0.1 0.4 0.1 1.6 0.3 4.5 1.8 1.1 1.1 1.2 0.5 0.2 0.0 1.5 1.7 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 2.5 71.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 178.4 0.1 355.1 0.9 0.1 0.1 0.4 1.0 0.7 0.1 1.3 0.3 0.7 1.0 0.0 0.1 0.1 0.1 0.7 0.8 0.7 0.6 0.3 0.8 1.2 5.0 4.6 3.2 4.5 1.2 0.9 0.2 0.0 2.5 0.0 4.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.3 1.5 1.4 0.0 0.0 0.1 2.8 0.0 0.0 0.0 2.4 28.0 0.3 0.1 0.0 0.8 0.7 0.0 0.0 0.2 0.0 0.5 19.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.3 5.7 0.0 0.1 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 9.9 0.8 0.0 0.1 13.9 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;retina: 10.6;testis: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 22.9;Excitatory neurons: 45.0;Muller glia cells: 89.1;Oligodendrocyte precursor cells: 96.0" "Cancer enriched" "Detected in some" 5 "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;JURKAT: 5.7;MOLT-4: 4.3;U-2 OS: 9.6;U-251 MG: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 0.3 0.3 7.0 0.2 6.7 0.5 0.0 0.0 8.0 0.1 0.0 1.6 0.1 0.1 0.4 0.1 0.2 0.3 1.4 8.7 4.4 2.8 0.4 0.4 0.2 0.0 4.8 0.1 0.1 0.0 1.4 0.1 0.2 0.8 0.3 10.6 0.1 1.1 0.1 0.0 0.2 0.7 0.0 0.1 0.1 8.8 12.8 1.1 0.1 0.2 0.2 0.3 0.1 1.5 0.0 0.0 7.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.8 1.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.2 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 4.3 0.0 2.7 0.1 0.0 0.0 0.2 0.5 0.5 0.1 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 9.6 0.0 5.4 1.8 0.0 0.4 1.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 6.7 0.0 8.0 8.7 4.4 0.0 4.8 0.2 0.0 12.8 1.5 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 4.3 0.0 0.6 0.0 6.2 0.0 2.0 0.2 0.0 0.1 12.7 0.0 0.1 0.2 1.2 0.0 45.0 0.2 0.3 0.6 0.0 0.1 0.0 1.7 0.4 1.6 0.1 1.7 17.6 0.0 0.0 0.0 0.0 18.8 0.6 0.2 0.0 5.6 0.6 89.1 0.0 96.0 16.5 0.1 0.2 0.0 0.9 0.0 0.0 4.9 0.0 8.8 0.0 8.8 0.5 4.8 2.0 0.0 0.0 0.3 0.5 0.1 0.3 0.0 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 205.8" "Group enriched" "Detected in many" 7 "Endothelial cells: 150.4;Hepatic stellate cells: 268.4;Leydig cells: 285.2;Peritubular cells: 455.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CACO-2: 16.7;HHSteC: 6.7" HPA061343 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA061343: AB_2684483" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (5.26e-2)" "unprognostic (6.78e-3)" "unprognostic (1.59e-1)" "unprognostic (3.39e-4)" "prognostic favorable (5.72e-4)" "unprognostic (3.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (9.07e-2)" "unprognostic (4.97e-2)" "unprognostic (1.62e-2)" "unprognostic (1.43e-2)" "unprognostic (9.71e-2)" "unprognostic (1.58e-2)" 64.5 51.2 3.1 2.7 6.0 0.7 10.2 7.9 13.1 6.4 9.3 9.5 2.8 16.0 25.4 15.0 43.8 8.3 75.6 7.6 8.7 20.0 23.3 205.8 7.6 9.6 6.0 17.7 11.3 5.7 7.8 33.7 5.6 29.6 4.6 0.5 9.1 48.0 14.4 4.2 8.5 25.7 2.5 13.0 12.7 15.8 4.8 1.7 21.3 13.2 4.0 11.1 7.2 16.6 0.0 0.1 0.0 0.1 1.5 2.1 0.3 0.2 2.1 0.0 0.0 16.7 0.1 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 6.7 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.2 0.2 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.1 0.6 0.0 0.6 0.1 0.0 1.0 0.0 0.6 0.2 0.0 0.7 0.3 0.0 0.2 0.1 0.3 1.6 0.2 0.2 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.4 0.2 0.2 0.8 0.5 0.1 0.3 0.1 0.2 3.1 6.0 7.9 13.1 7.6 8.7 9.6 6.0 5.6 2.5 4.8 16.6 39.4 0.0 3.6 0.0 1.0 2.2 0.1 0.0 1.2 0.0 0.4 0.6 10.0 7.2 2.5 0.0 0.0 0.7 0.3 0.0 0.0 0.0 2.3 0.1 0.8 150.4 1.2 8.0 0.0 0.0 0.4 38.2 0.0 0.0 0.0 0.9 268.4 5.1 0.8 0.0 0.0 0.2 0.0 16.6 4.4 16.0 285.2 0.7 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 455.5 1.5 0.2 0.0 0.1 0.7 0.0 32.9 5.0 19.6 1.3 1.3 0.4 2.3 1.8 1.3 0.2 0.0 0.4 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 6.7" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 22.5 16.9 26.8 12.0 85.5 9.5 17.3 56.9 30.4 29.6 10.9 54.2 19.2 49.5 19.5 29.6 30.7 15.2 75.0 20.4 21.3 14.1 14.6 25.1 8.4 20.5 37.7 19.5 12.8 12.2 14.7 28.8 20.4 24.5 16.7 16.9 13.5 23.6 75.4 22.9 23.4 42.1 17.5 13.9 27.6 22.9 50.5 6.8 14.1 50.3 7.3 35.5 22.7 27.0 35.4 13.7 22.6 21.9 33.8 23.7 18.4 36.4 27.9 23.3 15.4 32.6 14.0 3.1 13.7 38.8 15.1 19.5 24.8 15.2 27.9 10.8 14.4 5.1 17.3 44.7 24.3 12.9 11.9 16.0 14.9 15.0 28.2 18.6 16.3 6.6 7.6 18.2 12.6 28.3 3.6 40.9 10.5 21.0 24.3 7.6 14.9 5.6 19.4 19.9 5.4 18.5 18.3 26.5 22.6 20.5 17.2 30.4 13.7 14.9 17.2 20.1 21.6 3.6 18.4 11.0 14.4 8.6 6.5 6.7 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.3 26.8 85.5 56.9 30.4 20.4 21.3 20.5 37.7 20.4 17.5 50.5 27.0 14.7 9.6 19.7 14.7 4.5 5.4 4.4 1.9 0.0 10.5 7.1 5.3 10.1 4.3 6.4 7.3 0.0 3.9 5.0 24.8 0.0 6.5 12.3 2.8 22.8 10.0 6.1 3.2 33.5 9.2 3.7 5.6 6.6 5.9 8.8 8.6 15.0 17.9 2.9 8.4 25.2 9.9 2.0 7.2 12.0 17.0 7.2 6.9 1.8 19.7 4.1 9.6 0.0 18.1 29.2 12.1 11.5 11.7 2.5 6.5 13.8 4.3 2.5 5.2 6.6 6.5 24.3 6.3 7.3 2.8 5.8 2.5 2.7 10.7 13.9 8.6 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 79.5;Inhibitory neurons: 130.5;Late spermatids: 88.6;Oligodendrocytes: 70.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 91.4;SK-MEL-30: 149.0;SuSa: 181.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 9.9 16.8 53.8 9.9 49.4 4.7 7.6 45.3 63.9 15.7 10.1 15.5 4.6 15.4 22.8 9.3 8.3 6.9 5.9 50.6 135.3 10.5 3.2 9.1 10.7 71.2 57.3 12.3 6.7 7.4 57.1 10.9 75.0 10.9 8.0 32.9 10.8 10.0 11.0 13.7 9.5 13.2 50.3 7.5 8.6 14.8 62.7 7.0 10.5 3.8 13.0 9.2 12.5 55.2 13.5 8.2 91.4 14.3 6.9 10.6 8.5 18.4 9.3 8.4 8.4 12.0 15.2 8.3 7.6 19.7 10.6 14.4 7.9 9.8 11.9 6.0 10.3 6.5 3.9 11.0 13.5 4.4 19.0 9.7 8.6 14.2 13.5 15.7 23.2 6.1 5.7 13.8 20.8 7.0 5.5 15.7 9.2 9.9 12.0 7.0 18.8 2.3 12.5 5.3 6.5 70.2 19.8 7.2 149.0 181.5 4.3 3.4 19.6 9.9 12.2 11.0 17.5 15.2 7.7 4.5 11.0 12.8 32.3 0.9 3.4 1.3 1.0 3.0 1.3 6.7 2.2 1.3 6.2 9.1 2.2 1.1 0.8 3.4 3.6 1.4 5.3 1.9 53.8 49.4 45.3 63.9 50.6 135.3 71.2 57.3 75.0 50.3 62.7 55.2 7.8 6.4 4.8 52.5 21.5 9.1 11.7 7.5 10.2 24.2 6.9 9.5 5.4 1.5 7.8 12.9 16.7 9.3 7.9 15.1 11.7 3.6 58.7 4.3 18.3 8.6 1.2 5.2 79.5 4.5 10.6 7.9 5.1 6.9 2.5 9.7 4.2 3.5 9.9 42.1 130.5 5.6 10.2 6.0 27.8 88.6 5.3 13.1 19.6 34.7 16.3 21.7 6.2 52.8 70.5 6.8 6.6 3.8 4.7 8.2 6.5 24.7 4.0 21.6 6.6 7.8 13.8 22.4 41.0 13.1 10.4 13.3 7.7 19.3 6.5 13.1 IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 7.3;Basal squamous epithelial cells: 12.5;Bipolar cells: 11.5;Excitatory neurons: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA003243: AB_1079877, HPA003445: AB_1079875" 22.0 5.1 82.3 9.7 90.6 2.2 15.4 84.9 165.9 9.2 56.6 49.8 4.5 19.6 6.3 15.4 18.2 12.5 57.2 83.9 73.9 17.8 14.3 19.6 2.2 93.5 88.0 4.4 2.7 1.1 7.3 23.6 92.0 17.7 6.8 14.2 6.5 20.4 27.6 5.7 12.8 25.9 81.5 4.3 18.3 4.7 87.2 2.5 5.7 3.2 1.8 35.8 10.8 110.5 87.9 14.8 28.9 34.4 6.6 6.3 25.1 73.6 17.3 59.4 40.5 55.6 20.9 4.4 46.4 24.6 22.6 34.8 11.3 24.9 48.5 72.7 27.6 0.1 31.2 2.8 7.7 4.2 0.5 6.5 20.8 26.5 31.1 49.3 44.5 4.9 0.0 0.3 27.7 3.9 0.3 0.0 24.2 7.0 31.9 10.2 58.4 0.0 57.6 4.7 5.8 26.8 39.8 16.7 21.8 32.9 9.8 0.8 37.6 34.0 47.5 22.9 101.5 0.3 0.5 0.4 19.1 12.4 92.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.3 90.6 84.9 165.9 83.9 73.9 93.5 88.0 92.0 81.5 87.2 110.5 4.7 6.4 0.0 1.0 0.1 1.5 7.3 0.8 12.5 11.5 0.3 0.9 0.6 0.0 1.4 1.8 6.2 0.0 0.1 0.3 0.0 0.9 2.0 2.1 0.8 5.7 0.0 0.0 11.3 0.6 0.0 3.1 0.0 2.3 2.5 0.0 1.8 0.6 0.0 0.0 4.7 0.2 0.0 0.3 1.2 0.6 0.3 1.2 0.0 0.0 0.6 0.5 0.0 0.0 0.6 1.2 0.0 1.2 0.0 1.3 0.0 4.2 2.4 0.6 0.0 2.5 5.4 0.1 0.4 3.5 0.9 0.0 0.5 0.0 0.2 1.6 IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 7.4;Hofbauer cells: 11.1;Smooth muscle cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cell line enhanced" "Detected in some" "ASC diff: 20.8;BJ: 15.3;BJ hTERT+: 17.6;fHDF/TERT166: 6.9;REH: 6.8" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" 29.7 8.0 64.6 18.2 85.8 1.5 16.1 50.4 53.4 55.4 17.7 67.6 8.5 60.8 16.1 37.5 45.6 33.2 10.1 54.5 54.3 9.3 2.1 13.3 3.7 65.8 71.4 20.2 2.9 2.7 3.8 11.8 54.4 37.9 17.3 1.7 4.1 39.5 6.7 9.3 22.0 69.1 55.2 7.1 33.7 8.2 89.8 2.3 10.2 8.1 1.8 43.8 21.9 48.8 0.1 0.0 4.2 0.0 20.8 4.1 0.2 15.3 17.6 0.0 0.0 0.4 1.7 0.0 0.1 6.9 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.7 0.0 0.1 0.2 0.0 0.2 4.8 0.4 0.0 0.1 0.0 1.2 0.0 0.6 0.1 0.3 0.0 0.1 0.3 0.5 0.0 0.1 6.8 0.0 0.3 0.0 0.0 0.0 3.1 0.0 2.6 0.0 4.4 0.0 0.5 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 6.0 0.0 0.7 2.2 1.7 0.0 3.9 0.0 0.8 0.0 0.0 0.6 0.9 0.0 0.0 24.0 0.0 5.7 0.1 0.0 0.7 64.6 85.8 50.4 53.4 54.5 54.3 65.8 71.4 54.4 55.2 89.8 48.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 IRX3 IRX-1 ENSG00000177508 "Iroquois homeobox 3" P78415 16 54283304-54286787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 89.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 66.7;Breast glandular cells: 133.8;Breast myoepithelial cells: 84.6;Endometrial ciliated cells: 73.0;Glandular and luminal cells: 88.2;Respiratory ciliated cells: 67.3;Squamous epithelial cells: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 119.4;NB-4: 204.4;RPTEC TERT1: 236.4;T-47d: 122.9;THP-1: 201.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066576 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA066576: " "unprognostic (4.21e-3)" "unprognostic (4.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" "unprognostic (9.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (3.15e-2)" "unprognostic (5.40e-2)" "unprognostic (2.39e-1)" "unprognostic (8.20e-2)" "unprognostic (1.25e-1)" 8.2 6.8 3.4 0.4 3.0 0.1 75.6 6.3 1.2 29.7 2.7 0.3 0.4 2.2 36.5 33.0 10.9 0.3 63.1 1.2 5.1 42.6 2.2 36.5 2.0 7.5 8.1 0.9 4.0 27.2 7.2 1.9 6.2 23.2 0.0 1.2 43.2 31.3 22.7 89.3 0.6 1.2 6.2 0.1 22.5 0.5 7.5 1.0 9.3 8.8 4.5 4.8 17.5 5.0 1.1 1.1 15.6 15.1 8.4 3.3 1.7 6.6 14.5 13.9 3.4 4.2 6.8 0.0 2.2 10.0 5.5 29.0 12.6 3.6 18.5 14.3 9.8 0.0 22.2 14.6 0.6 16.7 4.1 2.5 59.7 26.5 12.0 9.8 0.0 19.1 0.0 0.0 119.4 7.7 30.9 204.4 1.1 0.0 0.0 23.2 19.2 0.0 236.4 6.2 10.6 1.9 20.4 51.3 2.6 1.7 122.9 201.8 3.4 57.9 6.4 10.6 5.3 0.0 0.0 0.1 38.0 53.7 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.0 6.3 1.2 1.2 5.1 7.5 8.1 6.2 6.2 7.5 5.0 2.6 19.2 66.7 0.0 0.4 25.0 47.4 25.3 45.5 1.3 133.8 84.6 14.1 0.0 43.2 5.5 0.0 0.1 1.3 0.1 1.9 5.2 0.0 73.0 8.1 5.8 0.0 0.0 0.0 0.2 0.1 18.3 2.0 88.2 0.0 5.5 8.2 7.1 0.3 0.0 0.0 0.0 36.7 1.2 2.7 0.0 0.0 9.0 10.6 0.0 0.2 10.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 25.8 0.0 6.5 67.3 1.2 0.0 32.1 6.4 0.4 1.0 72.8 41.3 0.0 1.1 0.1 0.0 34.0 IRX4 ENSG00000113430 "Iroquois homeobox 4" P78413 5 1877413-1887236 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.8;heart muscle: 14.3;skin 1: 22.5;vagina: 12.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 48.6;Basal squamous epithelial cells: 50.7;Breast myoepithelial cells: 15.6;Prostatic glandular cells: 13.3;Squamous epithelial cells: 26.5;Suprabasal keratinocytes: 20.2" "Group enriched" "Detected in many" 5 "cervical cancer: 5.4;head and neck cancer: 7.3;lung cancer: 1.8;prostate cancer: 6.9;testis cancer: 7.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.8;HaCaT: 16.3;HBEC3-KT: 8.1;MCF7: 8.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "medulla oblongata: 1.2;pons: 1.5" HPA064094 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Vesicles" "HPA064094: " "unprognostic (1.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (7.52e-2)" "unprognostic (7.54e-2)" "unprognostic (4.26e-1)" "unprognostic (1.70e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 3.2 0.7 0.0 3.7 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 14.3 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.9 0.0 1.2 9.9 0.0 0.0 9.5 0.0 0.6 22.5 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 16.3 0.0 8.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 8.3 1.1 0.1 0.1 4.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 3.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.8 0.7 1.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 48.6 2.8 0.1 50.7 0.0 1.4 15.6 6.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.1 26.5 20.2 3.7 0.0 0.0 0.0 1.7 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.5;Extravillous trophoblasts: 391.9;Hepatic stellate cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 615.4;HUVEC TERT2: 1360.8;TIME: 1277.7;U-87 MG: 623.6" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" 114.4 47.1 8.7 136.2 9.2 46.4 69.1 9.2 13.8 64.0 9.7 398.8 15.3 106.1 5.0 72.3 71.1 50.8 113.9 8.5 9.0 26.6 48.6 121.7 17.5 11.3 9.9 39.3 20.9 14.9 10.5 91.6 11.3 141.9 40.6 1.3 24.5 114.9 29.1 50.5 87.6 361.9 10.6 16.3 90.8 4.0 17.1 13.2 40.5 25.7 12.5 386.5 76.9 9.8 65.4 23.9 43.6 0.6 130.8 278.7 113.5 286.0 308.2 300.9 220.6 17.1 15.3 0.5 206.9 308.5 149.1 10.1 12.5 81.4 197.4 0.4 12.2 28.1 31.3 1.1 179.5 88.7 44.4 206.8 39.2 351.9 258.3 615.4 1360.8 15.6 25.6 0.8 165.4 6.4 13.7 99.2 18.1 4.2 19.1 13.7 29.2 6.2 46.9 1.1 0.1 0.6 57.7 4.3 2.2 93.8 7.1 79.9 1277.7 353.0 62.3 85.9 121.5 0.3 3.6 0.7 623.6 83.0 118.5 16.4 64.9 0.5 14.2 27.3 11.2 0.1 10.9 10.9 62.6 0.3 7.7 6.6 89.1 26.4 24.0 3.4 4.9 42.9 8.7 9.2 9.2 13.8 8.5 9.0 11.3 9.9 11.3 10.6 17.1 9.8 58.3 3.2 4.4 1.6 2.7 14.3 3.4 11.3 4.0 1.1 6.1 2.8 16.3 14.3 4.9 0.0 0.0 5.4 19.6 0.0 0.0 34.0 0.3 1.7 32.1 101.5 0.0 3.4 1.4 3.4 391.9 45.0 0.5 3.0 19.7 5.1 88.9 27.1 28.4 0.0 1.2 0.0 2.0 22.8 58.5 0.5 6.5 38.5 10.6 14.0 24.6 0.0 21.6 0.0 0.2 8.8 0.0 4.5 8.7 3.6 0.0 0.2 1.8 1.1 13.1 11.1 30.7 0.2 0.7 1.3 10.7 34.6 14.3 2.4 0.0 2.0 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 118.6;monocytes: 36.8;NK-cells: 152.4;Plasma cells: 46.6;T-cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "HMC-1: 608.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" 4.2 1.4 0.3 36.7 0.5 36.8 2.3 0.3 1.0 2.4 0.5 5.5 6.0 2.3 1.0 2.5 3.0 7.0 1.4 0.3 0.4 2.6 10.6 22.0 62.4 1.6 1.1 1.3 1.0 0.5 1.2 3.0 1.4 2.4 8.6 0.0 5.3 1.4 0.9 1.4 19.7 3.6 0.7 64.9 8.6 1.0 1.6 55.2 3.5 0.9 46.4 6.9 2.3 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.1 0.0 1.1 608.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 134.3 0.0 0.0 43.3 3.5 0.0 0.0 0.0 0.1 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 26.0 0.0 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.1 3.8 0.0 5.3 24.4 17.0 56.6 48.0 27.7 4.8 21.4 42.7 22.3 1.7 9.4 29.7 14.3 24.2 121.7 6.0 15.6 43.6 0.3 0.5 0.3 1.0 0.3 0.4 1.6 1.1 1.4 0.7 1.6 2.1 1.2 6.4 10.5 0.7 19.1 0.8 0.3 0.0 0.0 0.4 1.2 1.0 1.9 0.0 1.9 1.8 0.0 0.2 118.6 0.3 0.0 0.1 0.5 4.1 0.6 2.3 0.0 4.8 3.6 0.0 0.6 1.4 1.1 0.9 5.1 0.1 5.3 4.9 19.3 0.0 2.8 0.2 0.0 30.0 3.4 0.7 0.0 31.5 1.8 15.9 36.8 0.1 152.4 0.5 1.6 0.0 0.0 0.0 46.6 0.1 0.9 0.3 6.7 0.9 0.0 1.2 0.7 0.2 0.2 0.1 0.3 0.7 84.9 0.1 0.0 0.2 ITGB1BP2 CHORDC3 ENSG00000147166 "Integrin subunit beta 1 binding protein 2" Q9UKP3 X 71301750-71305371 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.4;skeletal muscle: 46.1;tongue: 52.9" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 80.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA040721 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA040721: AB_10805827" "unprognostic (1.87e-1)" "unprognostic (2.65e-2)" "unprognostic (6.91e-5)" "unprognostic (1.95e-2)" "unprognostic (7.92e-2)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (9.02e-2)" "unprognostic (4.69e-2)" "unprognostic (2.15e-2)" "unprognostic (4.85e-2)" "unprognostic (3.17e-1)" "unprognostic (3.08e-11)" "unprognostic (4.38e-2)" "unprognostic (3.63e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-1)" 0.7 0.6 0.5 1.5 0.6 1.5 0.5 1.0 0.9 2.4 0.5 6.5 1.0 16.6 3.0 4.1 3.3 2.5 89.4 0.6 0.6 0.8 1.4 1.0 0.9 0.6 0.6 1.6 0.5 0.0 0.5 0.3 0.6 6.0 1.8 1.8 1.3 10.3 46.1 0.6 2.1 16.3 0.5 1.1 2.0 1.3 0.6 1.0 0.7 52.9 0.6 5.5 1.5 0.7 0.5 1.4 2.1 1.8 0.1 0.1 0.4 0.7 1.0 0.5 0.5 0.9 1.1 2.1 0.2 1.1 0.5 0.9 1.9 0.6 1.1 0.7 0.9 1.3 1.5 0.4 0.2 0.4 9.3 1.1 0.7 0.2 0.3 0.4 0.8 2.2 1.0 0.5 1.1 0.4 0.8 2.3 3.1 1.4 0.9 1.4 1.6 0.8 1.0 1.3 1.0 0.3 0.5 0.1 0.6 1.4 0.5 0.3 0.0 0.9 1.8 0.1 0.4 1.8 2.8 3.1 0.2 1.6 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.0 0.9 0.6 0.6 0.6 0.6 0.6 0.5 0.6 0.7 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.7 0.3 0.3 80.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.6 0.1 0.2 0.2 0.8 0.0 0.4 0.2 0.0 0.1 2.3 0.0 0.2 0.0 0.4 1.1 0.8 0.2 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.3 0.1 1.0 0.0 0.5 0.2 0.1 8.6 0.0 0.3 0.1 0.5 0.3 1.1 0.0 0.6 2.5 0.5 0.4 0.0 0.3 0.0 0.1 0.6 0.3 0.1 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "melanoma: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "WM-115: 50.7" HPA000506 Uncertain "Secreted to blood" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "HPA000506: AB_2666007" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (9.73e-3)" "unprognostic (7.24e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-3)" "unprognostic (9.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (4.14e-4)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847840 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 290.2;Inhibitory neurons: 183.1;Microglial cells: 84.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Immune cell enhanced" "Detected in many" "naive B-cell: 13.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.4;HEL: 41.1;HeLa: 74.9;HMC-1: 40.0;U-87 MG: 56.7" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 208.8" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" 10.6 12.0 1.8 11.8 12.0 7.2 17.3 49.9 20.1 11.5 15.6 19.5 4.5 36.5 10.0 10.6 27.1 14.1 10.1 5.9 0.0 13.9 3.9 13.7 11.2 0.0 0.5 25.3 6.7 45.3 16.0 8.0 0.0 21.7 6.3 3.9 16.1 27.9 3.0 5.0 11.5 24.5 0.0 9.2 11.1 4.5 0.0 10.3 31.7 5.3 10.5 27.9 11.8 6.1 0.4 4.1 1.0 3.0 27.7 1.9 11.8 0.9 0.5 1.3 0.8 1.3 1.2 14.5 0.6 1.9 6.5 0.1 2.2 2.6 2.1 76.4 3.2 41.1 74.9 3.5 27.4 17.7 40.0 9.2 4.0 5.8 1.1 7.6 7.2 8.4 7.9 13.9 3.7 1.8 7.2 3.0 2.1 0.5 9.7 4.2 1.0 1.1 1.7 5.5 0.7 19.5 5.4 4.3 4.3 0.9 2.6 20.6 13.5 1.8 4.3 3.7 2.3 17.7 12.0 9.6 56.7 17.0 2.7 5.8 2.0 1.5 2.3 0.9 1.7 6.7 1.6 1.6 2.2 13.4 2.7 1.6 1.8 1.8 0.9 4.7 1.4 1.1 1.8 12.0 49.9 20.1 5.9 0.0 0.0 0.5 0.0 0.0 0.0 6.1 30.1 0.0 31.4 24.8 49.7 3.8 6.1 6.3 11.4 4.0 40.0 29.7 8.0 2.8 11.2 9.2 0.0 0.5 17.8 0.3 3.9 2.4 5.4 9.1 11.9 31.2 3.5 8.4 290.2 5.1 0.5 21.5 20.4 12.7 26.5 22.6 36.0 2.0 4.7 1.7 183.1 1.3 2.0 12.9 17.4 7.9 30.1 23.9 7.2 84.3 14.2 4.3 6.2 25.1 12.7 1.5 1.2 52.6 8.8 5.4 0.3 3.9 13.1 1.5 39.5 8.8 28.2 1.5 2.9 4.9 3.1 1.0 25.7 22.0 0.8 3.3 ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 10 "Early spermatids: 170.7;Late spermatids: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cell line enhanced" "Detected in many" "HEK 293: 30.9;HEL: 32.0;MOLT-4: 34.5;RPMI-8226: 33.0;U-698: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" 3.4 0.4 0.5 2.9 1.0 1.1 3.8 3.2 0.7 0.9 0.3 0.9 1.2 0.5 0.5 1.5 0.8 1.6 1.3 0.5 0.5 0.5 0.5 1.4 3.9 0.9 0.5 0.4 1.4 0.5 0.4 1.2 0.8 2.0 0.9 0.9 7.5 1.5 1.5 0.8 1.7 1.0 0.6 2.6 1.2 27.8 0.6 5.1 0.7 2.0 4.2 1.5 1.2 0.8 0.0 0.0 7.3 0.1 0.8 1.9 8.3 1.6 8.7 7.2 14.1 3.3 0.3 0.0 0.1 3.1 0.1 0.7 25.4 0.0 8.1 15.7 30.9 32.0 0.2 14.4 3.9 0.1 0.0 5.4 0.0 8.3 0.0 0.0 4.7 20.4 0.0 10.6 0.2 0.0 34.5 5.0 10.5 0.0 0.0 22.7 23.1 33.0 0.3 0.0 21.2 14.2 0.0 0.0 0.1 4.4 0.0 5.3 2.4 0.0 0.8 0.1 0.1 15.4 21.4 35.3 4.1 0.0 6.8 0.4 0.2 0.0 10.2 0.2 12.9 1.6 3.3 9.7 1.2 0.4 0.7 4.1 0.1 2.7 0.0 0.5 6.3 2.3 0.5 1.0 3.2 0.7 0.5 0.5 0.9 0.5 0.8 0.6 0.6 0.8 9.4 3.2 0.0 0.0 2.3 0.3 4.8 1.8 2.2 0.7 3.6 2.9 0.7 2.8 3.5 0.0 4.2 0.9 6.9 1.0 0.0 0.1 170.7 0.2 0.6 2.7 0.0 1.7 0.2 0.2 2.3 0.9 0.5 0.1 0.0 0.8 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 2.4 145.2 1.2 1.8 1.8 0.0 0.3 4.3 11.3 0.0 0.0 0.3 0.1 0.7 7.6 3.3 0.0 0.3 0.8 1.7 6.6 0.6 2.9 3.6 2.8 1.7 1.0 0.4 14.8 0.3 0.4 1.3 IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 162.3;esophagus: 298.3;salivary gland: 94.5;skin 1: 160.9;vagina: 235.2" "Cell type enhanced" "Detected in some" "Club cells: 10.4;Squamous epithelial cells: 30.8;Suprabasal keratinocytes: 71.0;Urothelial cells: 13.3" "Group enriched" "Detected in many" 5 "cervical cancer: 44.0;head and neck cancer: 145.4;melanoma: 50.9;urothelial cancer: 47.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "HaCaT: 292.9;RT4: 76.9;SK-BR-3: 86.3" "Not detected" "Not detected" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 4700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Nuclear bodies, Centrosome" "CAB002243: AB_563785, HPA055211: AB_2682739" "unprognostic (3.29e-4)" "unprognostic (1.91e-1)" "unprognostic (2.92e-2)" "unprognostic (2.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 162.3 0.0 0.0 0.0 0.0 18.2 298.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.0 94.5 0.1 0.4 160.9 0.1 0.0 0.0 0.1 0.2 0.1 0.0 3.5 0.1 0.0 36.9 17.4 235.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 292.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 0.0 0.0 0.0 86.3 0.0 0.2 3.6 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 3.1 3.5 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.6 0.0 0.0 30.8 71.0 0.0 0.1 0.0 0.0 13.3 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Kupffer cells: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Cell line enhanced" "Detected in many" "HHSteC: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" 53.5 20.0 23.2 29.3 22.0 78.6 40.2 22.8 28.2 31.6 22.0 31.6 22.5 22.7 3.7 25.4 28.5 27.7 39.1 23.5 24.2 18.9 20.5 47.2 13.1 24.6 22.9 21.6 23.1 8.1 17.3 17.5 22.6 21.8 11.3 16.4 24.2 15.0 21.9 29.1 30.1 20.9 22.6 66.8 23.3 4.7 25.4 4.8 25.1 16.7 10.6 25.3 31.6 21.8 15.5 13.5 2.5 26.8 81.5 60.2 90.5 47.5 51.0 30.4 38.1 33.0 13.5 12.4 23.5 90.7 5.6 59.5 16.7 16.2 13.1 16.7 1.9 17.0 26.0 11.9 167.1 24.1 1.3 106.5 95.2 12.4 30.6 11.9 1.5 13.8 2.2 23.0 27.7 76.4 1.4 39.8 9.1 30.4 8.7 8.2 0.3 34.0 14.8 8.6 2.1 10.4 48.9 69.4 55.1 29.7 66.4 52.1 6.2 38.1 57.5 2.4 7.0 18.7 6.0 28.8 11.5 90.0 19.1 0.1 4.5 4.4 0.0 8.1 0.0 11.8 0.2 0.0 2.4 5.1 0.0 0.0 7.7 0.1 13.2 2.1 0.2 1.4 23.2 22.0 22.8 28.2 23.5 24.2 24.6 22.9 22.6 22.6 25.4 21.8 70.7 12.8 33.5 26.8 9.9 16.4 6.0 5.8 19.9 21.8 26.2 18.2 17.7 12.8 8.1 9.2 10.4 1.4 1.2 20.0 0.0 2.4 0.3 21.6 18.4 21.2 5.4 0.8 18.9 6.6 5.6 49.5 10.2 23.9 2.5 10.1 10.4 8.5 9.7 8.4 20.8 14.9 4.1 87.7 25.7 1.5 18.0 47.3 12.4 14.0 13.8 38.6 2.1 18.1 3.0 8.5 8.2 16.6 9.8 2.6 17.7 3.0 7.4 31.1 6.6 47.2 19.5 0.1 0.9 19.7 8.9 0.3 2.2 5.3 8.7 11.5 JMJD7 ENSG00000243789 "Jumonji domain containing 7" P0C870 15 41828092-41837581 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 5.2;Basal squamous epithelial cells: 1.8;Gastric mucus-secreting cells: 2.0;Squamous epithelial cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 31.2;RT4: 43.5" "Low region specificity" "Detected in all" HPA005726 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA005726: AB_1852017" "unprognostic (2.92e-1)" "unprognostic (7.99e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.77e-1)" "unprognostic (2.42e-1)" "unprognostic (8.74e-3)" "unprognostic (3.13e-1)" "unprognostic (7.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" 6.7 8.4 6.3 4.2 6.2 8.2 9.0 19.9 9.5 13.6 8.0 7.3 4.8 6.5 3.1 35.4 8.6 6.5 11.2 5.8 6.3 10.1 10.3 10.8 7.3 5.8 5.2 11.6 15.9 9.0 9.8 3.0 7.0 14.5 3.0 1.9 21.9 6.8 7.7 33.3 8.0 2.9 5.1 7.9 11.5 6.7 5.9 5.6 15.6 6.6 6.6 11.4 21.0 7.0 7.9 7.5 9.3 2.6 2.5 1.7 5.8 3.1 6.6 5.1 4.1 10.5 5.9 1.0 6.4 2.0 5.3 19.6 4.3 15.6 1.6 7.7 4.6 10.5 10.4 6.5 4.1 5.1 11.0 1.1 13.6 3.4 7.2 4.7 5.8 9.9 7.0 6.2 3.7 10.8 6.6 4.9 4.0 31.2 4.8 2.9 6.3 7.6 11.5 43.5 9.9 3.5 2.6 13.5 4.3 2.7 26.2 5.4 5.4 3.7 8.3 8.0 6.1 10.2 3.7 3.2 4.9 12.4 5.7 6.1 14.8 10.8 14.1 15.8 14.8 7.2 15.7 18.6 10.6 11.1 19.7 15.6 3.9 13.0 15.8 6.7 16.7 12.6 6.3 6.2 19.9 9.5 5.8 6.3 5.8 5.2 7.0 5.1 5.9 7.0 0.1 3.2 5.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.2 2.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 3.4 0.1 0.0 0.6 0.0 0.0 0.0 JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.2;skeletal muscle: 120.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 15.3;EFO-21: 15.0;fHDF/TERT166: 19.1;HeLa: 12.6;SiHa: 12.9" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" 6.0 1.9 0.5 4.5 0.6 0.1 5.7 0.4 0.7 15.1 0.7 63.3 2.1 51.6 2.9 11.9 30.0 3.5 85.2 0.4 0.5 1.4 0.3 5.2 0.2 1.1 1.1 3.9 0.3 0.1 1.2 3.8 0.8 23.8 4.5 0.2 5.8 22.1 120.4 3.8 11.8 27.5 0.9 1.3 16.0 0.8 0.6 0.1 1.5 48.3 0.1 40.5 10.6 0.7 7.5 0.8 0.4 0.0 0.3 0.4 1.5 2.2 4.1 5.4 2.3 15.3 5.9 0.0 15.0 19.1 6.1 10.5 0.0 0.5 2.1 0.0 0.0 0.0 12.6 0.1 0.1 0.3 0.0 0.7 1.1 2.7 3.7 3.3 0.0 0.0 0.0 0.0 7.3 4.3 0.0 0.2 0.3 0.0 0.9 1.7 3.4 0.0 0.4 0.1 0.0 0.1 12.9 3.1 0.1 8.6 10.8 0.1 0.3 2.4 2.7 0.5 4.7 0.1 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.4 0.5 1.1 1.1 0.8 0.9 0.6 0.7 0.2 0.0 0.0 0.3 0.0 6.6 0.5 0.9 0.0 0.0 0.4 5.1 64.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.8 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 0.0 6.6 15.9 12.8 0.0 1.5 0.0 2.0 0.5 0.1 0.0 0.2 0.1 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KBTBD11 "KIAA0711, KLHDC7C" ENSG00000176595 "Kelch repeat and BTB domain containing 11" O94819 8 1973677-2006936 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Proximal enterocytes: 58.0;Proximal tubular cells: 32.2" "Cancer enhanced" "Detected in many" "renal cancer: 14.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;HEK 293: 2.0;MOLT-4: 1.4;REH: 1.8;SCLC-21H: 2.0;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051159 Uncertain Approved "Intermediate filaments" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "Intermediate filaments" "HPA051159: AB_2681367" "unprognostic (1.19e-1)" "unprognostic (2.27e-1)" "unprognostic (1.20e-3)" "unprognostic (2.70e-2)" "unprognostic (2.03e-1)" "unprognostic (6.84e-2)" "unprognostic (2.76e-4)" "unprognostic (2.50e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.75e-2)" "unprognostic (9.53e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-2)" 3.0 6.6 3.6 0.2 5.0 0.0 2.8 2.3 10.8 1.5 0.0 7.0 0.1 0.9 0.0 1.2 2.6 0.0 2.6 7.6 0.7 9.2 7.8 2.7 0.0 6.2 1.9 1.3 3.6 0.1 3.7 0.0 3.4 2.8 0.0 0.0 1.2 0.1 1.1 1.6 9.8 0.0 3.3 7.5 2.0 1.2 2.9 0.0 3.9 0.0 0.0 1.9 1.1 9.3 0.5 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 5.0 2.3 10.8 7.6 0.7 6.2 1.9 3.4 3.3 2.9 9.3 6.1 0.0 8.1 17.6 0.6 1.0 0.4 0.0 0.0 24.3 1.0 0.6 5.2 8.6 0.1 12.9 35.5 0.0 0.6 25.6 25.4 2.0 0.8 0.6 0.4 7.9 6.0 3.6 29.2 3.8 0.2 2.0 1.1 0.7 0.0 1.3 4.2 18.2 3.6 20.2 12.6 13.0 0.0 13.5 1.9 0.3 5.0 8.0 1.8 9.4 15.7 9.6 2.1 9.5 16.3 11.9 10.7 10.5 1.5 3.1 58.0 32.2 1.7 31.3 0.0 15.1 1.3 0.3 3.7 0.0 0.9 0.3 1.0 0.1 19.7 1.4 KBTBD12 "FLJ46299, KLHDC6" ENSG00000187715 "Kelch repeat and BTB domain containing 12" Q3ZCT8 3 127915232-127987671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 13.8;skeletal muscle: 58.8;tongue: 25.8" "Cell type enhanced" "Detected in many" "Astrocytes: 43.4;Early spermatids: 32.0;Excitatory neurons: 29.9;Microglial cells: 74.0" "Cancer enhanced" "Detected in some" "cervical cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 5.1" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.60e-2)" "unprognostic (2.19e-2)" "unprognostic (3.37e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (3.01e-1)" "unprognostic (3.35e-2)" "unprognostic (4.69e-3)" "unprognostic (3.62e-1)" "unprognostic (2.08e-1)" "unprognostic (2.28e-2)" "unprognostic (1.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.41e-2)" "unprognostic (5.70e-2)" "unprognostic (9.49e-2)" 0.3 0.2 1.3 0.3 1.5 0.2 0.2 1.6 1.6 0.2 2.7 1.8 0.8 0.3 0.1 0.7 0.9 0.7 13.8 1.6 0.6 1.2 0.0 0.2 0.1 0.7 0.7 0.1 4.0 0.0 0.5 0.1 0.7 0.5 1.2 0.7 1.9 0.2 58.8 0.3 0.7 0.7 0.5 0.0 2.0 1.0 0.7 0.0 0.0 25.8 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.6 1.6 1.6 0.6 0.7 0.7 0.7 0.5 0.7 1.2 0.0 3.2 3.7 43.4 0.0 0.1 0.1 0.0 0.0 1.0 0.4 0.1 12.1 0.0 1.4 1.8 6.2 0.0 0.1 2.3 1.9 0.1 32.0 1.3 0.0 0.2 2.4 1.7 29.9 9.3 0.0 0.7 7.1 0.8 0.0 0.1 0.0 0.0 0.1 1.7 15.7 5.8 0.0 0.0 1.0 3.2 0.0 0.3 0.0 74.0 0.0 1.6 0.0 3.0 2.2 5.9 5.8 0.0 0.1 0.0 1.4 0.0 1.2 0.9 0.0 1.6 1.0 6.2 5.7 0.0 0.3 0.0 0.0 0.1 1.9 0.1 KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 113.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 115.6;Cone photoreceptor cells: 212.7;Excitatory neurons: 150.6;Inhibitory neurons: 89.9;Rod photoreceptor cells: 386.9" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;CACO-2: 2.2;HL-60: 1.1;hTCEpi: 1.2;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" 10.7 1.5 4.3 0.3 6.6 0.0 2.8 0.0 17.8 1.2 0.0 6.2 0.2 7.3 0.8 1.7 6.0 0.6 1.2 6.6 0.0 0.3 2.4 0.3 0.0 0.0 0.0 0.4 0.3 0.2 2.7 0.1 0.0 2.2 0.6 113.3 1.6 3.1 7.3 0.5 2.0 5.0 0.0 0.3 3.4 0.4 0.0 0.1 0.1 4.4 0.0 3.8 0.9 7.9 0.0 0.0 0.3 0.0 1.4 0.1 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.9 0.7 0.6 0.9 0.0 0.0 0.7 0.0 0.0 0.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.6 0.0 17.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 7.9 20.2 0.0 2.2 7.8 0.5 0.8 0.2 0.0 0.0 115.6 0.9 0.5 3.4 1.5 0.7 0.0 212.7 0.0 0.4 0.0 0.0 0.0 0.7 19.8 2.9 8.0 0.0 0.0 150.6 0.0 0.0 1.4 0.0 4.2 3.8 1.5 0.0 5.7 0.1 18.5 89.9 0.0 0.0 0.0 0.3 0.8 4.4 0.4 0.0 12.2 0.0 38.2 0.0 43.2 3.3 0.1 0.0 34.6 0.1 0.1 0.0 0.2 4.0 386.9 0.0 0.9 7.0 0.2 0.5 0.2 0.3 0.1 0.4 0.2 0.0 0.1 KCNE1 "IsK, JLNS2, LQT5, minK" ENSG00000180509 "Potassium voltage-gated channel subfamily E regulatory subunit 1" P15382 21 34446688-34512210 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.3;fallopian tube: 10.0;heart muscle: 5.4" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 25.0;Endometrial ciliated cells: 23.8;Kupffer cells: 34.6;Macrophages: 20.3;Respiratory ciliated cells: 54.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 1.3;CACO-2: 4.0;HBF TERT88: 1.0" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (8.24e-3)" "unprognostic (9.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.71e-3)" "unprognostic (1.01e-3)" "unprognostic (2.98e-2)" "unprognostic (2.45e-2)" "unprognostic (1.47e-2)" "unprognostic (2.58e-1)" "unprognostic (2.06e-1)" "unprognostic (9.30e-2)" "unprognostic (7.90e-3)" "unprognostic (1.41e-2)" "unprognostic (3.27e-2)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" 0.5 0.1 0.4 0.3 0.3 0.5 0.9 0.4 0.9 0.7 13.3 0.1 0.0 0.3 0.2 0.2 10.0 0.0 5.4 0.5 0.1 1.7 1.1 1.5 0.0 1.0 0.9 0.0 0.0 1.0 0.3 0.1 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.2 1.4 1.0 0.2 1.5 0.9 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.3 0.4 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.2 0.4 0.3 0.4 0.9 0.5 0.1 1.0 0.9 0.6 1.4 0.9 0.3 0.8 3.2 1.8 0.0 0.6 0.8 0.8 3.3 0.0 1.9 1.0 2.0 6.4 0.0 2.8 0.0 25.0 0.0 0.3 0.8 0.0 0.7 4.8 23.8 0.6 1.9 0.0 2.7 1.4 0.4 0.4 1.2 0.5 4.6 0.0 0.0 1.4 7.3 3.7 0.0 1.6 0.0 2.0 34.6 1.2 2.2 0.3 20.3 0.0 1.9 4.5 0.1 0.0 1.5 2.2 0.5 0.1 0.0 0.1 0.4 0.9 0.2 54.2 1.9 0.0 2.1 1.4 0.9 0.1 0.2 0.3 0.0 0.6 0.0 0.1 1.0 KCNH2 "erg1, HERG, Kv11.1, LQT2" ENSG00000055118 "Potassium voltage-gated channel subfamily H member 2" Q12809 7 150944961-150978321 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.3;pituitary gland: 43.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 217.3;Cardiomyocytes: 83.2;Erythroid cells: 76.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 197.7;NB-4: 97.8;SH-SY5Y: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (6.06e-5)" "unprognostic (9.79e-3)" "unprognostic (1.95e-2)" "unprognostic (3.40e-2)" "unprognostic (3.84e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-1)" "prognostic favorable (5.61e-4)" "unprognostic (6.08e-2)" "unprognostic (2.26e-2)" "unprognostic (4.90e-2)" "unprognostic (2.83e-1)" "unprognostic (6.24e-2)" "unprognostic (3.02e-2)" 0.8 3.7 9.8 2.6 8.0 42.3 0.1 13.5 9.0 4.4 4.4 36.1 2.7 16.9 1.7 1.5 7.3 3.2 29.6 5.6 14.8 1.1 0.2 2.0 0.3 23.5 14.7 3.2 3.4 18.1 43.3 1.4 23.0 9.8 1.0 6.7 1.1 8.0 0.2 0.3 8.3 7.8 6.3 1.8 10.9 30.8 17.1 0.4 0.2 0.0 0.1 12.9 2.7 4.1 0.0 0.3 0.9 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 8.0 2.9 0.0 0.2 0.0 3.1 0.0 0.0 0.8 0.4 18.3 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 197.7 0.0 0.0 0.9 1.6 97.8 1.3 0.2 0.0 0.1 0.1 10.1 0.0 0.0 3.8 78.2 0.0 0.1 0.0 1.1 0.0 1.8 0.6 0.0 1.5 0.0 0.0 5.3 0.2 2.1 0.0 11.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 8.0 13.5 9.0 5.6 14.8 23.5 14.7 23.0 6.3 17.1 4.1 0.0 0.0 0.0 1.6 1.6 0.0 0.2 0.1 0.0 217.3 0.4 0.3 83.2 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.0 2.1 2.0 0.5 0.8 0.9 16.3 76.4 5.2 0.2 0.9 5.0 0.5 0.1 26.1 6.3 1.4 0.1 0.3 16.8 13.9 0.7 12.2 0.0 0.3 4.8 2.5 0.0 0.0 2.8 0.0 4.5 0.0 5.5 1.7 0.3 0.0 13.2 1.4 0.1 0.2 0.1 0.4 10.3 0.0 1.7 2.6 2.5 5.1 0.0 0.0 0.3 0.9 0.7 0.3 0.4 KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.8;kidney: 7.0;pituitary gland: 5.3;prostate: 3.9;retina: 4.4" "Group enriched" "Detected in some" 8 "Bipolar cells: 44.8;Cardiomyocytes: 25.6;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 34.6;Proximal enterocytes: 40.3;Proximal tubular cells: 14.1" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 3.3;SH-SY5Y: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.1;olfactory bulb: 2.4;spinal cord: 2.5" HPA061704 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" 0.0 0.1 0.9 0.0 1.1 0.2 0.0 0.9 1.1 0.0 0.3 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.6 7.0 0.0 0.3 0.0 1.6 1.5 0.0 1.3 0.0 5.3 0.1 1.7 3.9 0.2 4.4 0.0 0.0 0.1 0.1 4.8 0.0 1.1 0.1 0.8 1.2 1.5 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.9 1.1 0.6 1.6 1.6 1.5 1.7 1.1 1.5 1.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 44.8 0.0 0.3 25.6 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 3.0 0.6 0.1 1.3 34.6 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.0 0.0 3.4 0.0 0.1 1.8 0.0 0.0 1.1 0.0 0.5 0.1 0.1 1.2 0.0 0.0 1.4 40.3 14.1 0.0 3.1 0.0 0.2 1.0 0.0 0.7 0.0 0.1 0.1 0.1 0.0 0.8 0.1 KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 197.9;Cholangiocytes: 88.6;Proximal tubular cells: 236.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 68.7;GAMG: 103.6;HBEC3-KT: 69.6;RPTEC TERT1: 67.5;RT4: 80.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" 8.7 0.5 0.8 20.7 0.7 14.1 2.8 0.9 6.7 12.7 0.5 0.9 1.5 0.5 11.0 8.5 1.2 30.4 0.8 0.8 0.6 241.6 2.8 42.2 1.2 0.9 0.6 0.3 57.8 0.7 0.4 4.6 1.8 2.6 0.4 0.5 25.5 14.6 0.5 3.0 0.7 2.4 0.3 11.7 40.5 1.8 5.4 1.9 129.5 3.0 1.9 25.1 8.1 1.1 1.6 0.0 0.3 0.6 13.7 68.7 0.6 1.0 4.8 0.0 0.0 0.0 0.6 0.2 0.0 7.5 103.6 23.5 0.0 69.6 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.1 21.0 7.2 17.8 3.8 1.5 3.2 0.1 0.2 0.7 31.6 0.0 0.1 0.2 0.0 0.1 0.7 1.5 0.3 0.7 67.5 80.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.4 3.5 0.2 1.7 0.4 0.1 5.6 4.3 0.4 0.3 19.3 0.1 0.0 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.3 395.3 0.0 0.0 0.4 0.0 4.6 0.8 0.7 0.9 6.7 0.8 0.6 0.9 0.6 1.8 0.3 5.4 1.1 2.9 60.9 197.9 0.0 1.1 2.8 10.4 20.7 13.6 0.0 0.5 0.0 1.6 88.6 33.1 31.3 0.0 0.1 0.0 0.0 17.6 27.8 1.9 0.0 0.0 4.6 0.0 0.0 0.3 8.6 0.8 1.5 15.8 0.1 6.3 0.0 0.7 0.4 0.4 0.0 0.1 0.0 2.0 2.9 3.0 2.2 0.6 5.9 1.8 0.0 2.1 0.0 0.0 0.0 0.1 44.7 0.0 0.0 0.1 0.7 0.0 236.9 7.0 0.0 0.0 1.5 0.8 1.1 1.1 16.8 1.6 0.1 1.7 0.1 0.0 9.0 KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 138.7" "Cell type enhanced" "Detected in many" "Astrocytes: 471.1;Bipolar cells: 409.8;Excitatory neurons: 1023.7;Inhibitory neurons: 635.9;Oligodendrocyte precursor cells: 708.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.4" "Cell line enhanced" "Detected in many" "BJ: 100.8;hTERT-HME1: 115.3;PC-3: 159.6;U-138 MG: 112.6;U-87 MG: 109.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054648: AB_2682556" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (9.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (5.19e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-3)" 10.9 12.6 36.2 8.9 38.0 1.0 15.8 1.0 45.0 54.4 4.2 118.2 7.3 138.7 31.4 33.7 47.8 22.4 3.7 36.4 10.1 11.4 19.2 9.6 7.8 4.8 15.2 13.9 8.0 0.2 26.9 4.8 5.7 48.3 21.1 40.2 42.8 76.1 96.6 5.0 23.3 92.8 1.0 24.1 33.6 5.8 15.6 2.1 3.0 18.7 3.5 44.3 24.6 28.4 0.3 30.3 0.1 0.3 4.6 24.8 0.3 100.8 89.2 23.9 11.8 6.7 0.6 0.0 0.7 75.9 56.8 0.2 0.0 59.0 14.6 60.9 0.6 0.0 0.0 0.0 45.0 0.0 0.4 17.4 10.7 38.3 115.3 84.0 9.8 0.5 0.0 0.0 42.6 1.2 1.9 0.2 1.8 0.2 159.6 0.1 3.6 0.1 15.3 0.2 9.1 1.1 0.0 2.5 0.1 11.9 12.2 0.1 65.4 112.6 12.7 20.6 90.0 0.0 0.2 0.0 109.8 0.1 45.1 0.0 0.1 0.0 0.0 2.4 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.1 36.2 38.0 1.0 45.0 36.4 10.1 4.8 15.2 5.7 1.0 15.6 28.4 0.9 0.0 4.3 471.1 2.8 2.0 71.7 5.7 17.6 409.8 30.4 43.9 3.5 5.7 4.8 1.8 60.5 0.3 0.5 2.8 29.4 3.3 74.4 20.9 17.9 3.4 4.9 0.0 1023.7 10.7 0.2 16.2 0.5 29.7 0.0 1.9 2.5 27.3 10.8 6.7 635.9 59.6 46.8 106.0 3.9 63.1 3.7 36.7 48.0 133.0 4.0 52.3 0.0 708.2 33.9 8.7 1.4 1.2 8.7 64.0 1.4 0.9 0.1 17.2 6.6 20.6 19.2 3.4 2.5 7.7 0.3 0.3 0.7 177.2 1.7 2.4 KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 59.2;intestine: 75.1;smooth muscle: 53.1" "Cell type enriched" "Detected in many" 6 "Peritubular cells: 354.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cell line enhanced" "Detected in some" "REH: 8.8;SK-BR-3: 2.1;U-937: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.06e-2)" "unprognostic (2.70e-4)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (8.88e-2)" "unprognostic (1.61e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (5.37e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (4.31e-2)" "unprognostic (1.04e-2)" 5.7 1.8 2.7 10.5 2.3 1.7 6.9 2.5 2.7 16.8 1.4 75.1 4.3 59.2 6.2 16.6 20.6 7.3 4.2 2.1 2.4 1.4 0.7 4.0 1.7 5.9 4.0 4.0 0.7 0.3 0.5 1.1 6.2 24.5 8.9 1.1 6.8 50.6 1.0 2.9 14.3 53.1 3.4 2.3 21.5 2.7 4.2 1.0 1.4 1.1 1.3 32.6 11.2 3.9 0.1 0.1 1.5 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.3 0.1 1.0 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.1 1.2 0.6 0.2 0.0 0.4 0.2 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.7 0.1 0.7 0.0 0.8 0.3 0.0 0.1 8.8 0.0 0.2 0.0 0.2 0.4 0.2 0.1 2.1 0.0 0.7 0.1 1.0 0.5 0.2 0.3 0.3 0.0 0.4 0.2 0.1 0.1 3.8 0.1 1.3 3.3 0.3 0.1 5.9 0.1 0.2 0.2 0.1 5.7 0.3 0.1 0.1 0.9 0.4 5.1 2.0 0.2 1.0 2.7 2.3 2.5 2.7 2.1 2.4 5.9 4.0 6.2 3.4 4.2 3.9 1.3 0.0 6.3 0.3 1.2 2.0 1.2 0.4 0.0 1.6 2.5 55.1 3.7 4.3 4.5 1.8 6.2 0.5 1.7 0.1 0.0 0.1 0.6 0.6 14.4 3.6 0.0 1.3 0.1 0.4 0.6 9.8 0.0 0.6 19.7 0.4 1.8 0.4 7.4 1.7 0.3 0.2 0.0 18.9 10.9 4.5 38.5 15.6 3.6 4.7 27.8 0.6 2.1 0.0 0.1 0.0 0.0 354.3 0.3 1.3 0.0 0.1 4.5 2.3 46.0 2.2 43.6 0.7 1.2 0.1 1.7 0.5 1.7 1.4 0.0 0.7 KCNQ4 "DFNA2, Kv7.4" ENSG00000117013 "Potassium voltage-gated channel subfamily Q member 4" P56696 1 40783787-40840452 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Hearing, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.1;intestine: 5.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 5.1;Inhibitory neurons: 9.7;Muller glia cells: 4.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 5.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.8;HEK 293: 2.2;K-562: 2.6;MCF7: 1.4;REH: 1.3;THP-1: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018305 Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA018305: AB_1855556" "unprognostic (1.42e-2)" "unprognostic (1.56e-1)" "unprognostic (8.43e-3)" "unprognostic (4.59e-3)" "unprognostic (8.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (5.86e-2)" "unprognostic (4.34e-2)" "unprognostic (6.64e-2)" "unprognostic (1.20e-1)" "unprognostic (7.40e-2)" "unprognostic (5.18e-4)" "unprognostic (2.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (3.44e-2)" 0.9 0.1 0.1 0.3 0.6 0.0 0.6 0.2 1.7 0.9 2.4 5.4 0.4 2.8 0.1 1.0 2.3 0.3 0.6 0.2 0.2 0.1 0.1 0.5 0.0 0.7 5.1 0.5 0.4 0.2 0.3 0.5 0.7 1.1 0.3 0.4 1.4 1.1 3.2 0.6 1.2 1.5 0.8 0.0 1.3 0.2 0.1 0.3 0.2 1.0 0.0 2.3 0.7 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 2.2 0.9 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 1.4 0.3 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.2 0.0 1.1 0.2 0.0 0.6 0.2 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 1.7 0.2 0.2 0.7 5.1 0.7 0.8 0.1 2.0 0.3 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 1.8 1.5 2.1 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 1.2 0.2 0.2 0.1 0.3 1.8 0.8 5.1 0.2 0.0 0.2 0.0 0.4 0.0 0.3 0.0 0.0 2.2 0.0 9.7 1.2 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 4.2 0.0 2.5 1.5 0.6 0.5 0.7 0.3 0.2 0.0 0.0 0.0 0.3 6.6 2.0 2.8 0.2 0.7 1.0 0.4 0.0 0.0 0.1 1.1 0.1 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD10 "BTBD28, MSTP028" ENSG00000110906 "Potassium channel tetramerization domain containing 10" Q9H3F6 12 109448655-109477359 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014273 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA014273: AB_1852159" "unprognostic (7.21e-3)" "unprognostic (3.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.32e-4)" "unprognostic (1.84e-2)" "unprognostic (1.85e-1)" "unprognostic (7.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.45e-1)" "unprognostic (7.72e-2)" "unprognostic (5.76e-2)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" 40.3 23.4 20.5 26.2 19.7 15.4 32.9 17.2 20.3 34.2 32.1 42.5 14.7 43.8 14.0 36.6 27.4 33.0 24.1 19.7 31.0 23.0 11.4 31.9 21.9 21.1 23.1 18.1 12.4 22.2 17.0 25.4 26.6 29.2 33.2 14.3 20.7 44.3 11.5 30.3 22.3 57.0 19.2 23.2 25.8 16.3 30.1 14.9 47.1 11.7 22.8 39.0 29.4 18.9 28.4 27.9 84.6 27.5 67.8 91.2 18.5 59.0 80.2 38.8 38.2 28.1 23.1 27.5 34.0 136.4 19.2 22.0 30.7 51.6 35.9 26.0 22.0 32.3 19.2 19.3 44.5 24.9 26.7 92.2 30.7 50.0 29.3 54.7 89.5 26.4 21.5 11.5 68.0 15.1 29.8 32.9 48.1 12.7 36.0 29.2 37.7 22.6 38.5 48.9 29.5 44.3 35.6 38.8 41.8 47.5 45.2 18.8 70.0 42.3 15.5 24.0 32.8 26.0 52.8 37.1 48.8 20.2 60.5 10.9 9.5 6.4 13.5 14.4 10.1 6.6 8.0 10.0 11.9 6.2 8.8 11.1 6.5 25.1 17.2 9.0 10.0 14.9 20.5 19.7 17.2 20.3 19.7 31.0 21.1 23.1 26.6 19.2 30.1 18.9 21.1 16.0 29.9 6.2 9.0 14.7 20.1 17.4 11.4 5.4 12.1 13.5 11.5 10.0 13.7 5.5 16.7 9.1 19.4 31.5 5.9 15.3 12.2 9.9 17.8 26.8 11.5 6.5 9.8 13.1 12.8 15.5 10.7 12.8 14.0 11.3 24.7 5.3 11.5 8.4 8.1 13.4 10.2 13.6 13.3 11.3 11.5 14.6 16.0 8.4 15.7 2.8 81.4 8.0 9.4 25.9 11.8 18.8 7.5 12.2 6.4 10.5 12.2 4.4 26.3 13.4 32.6 13.5 6.3 10.2 16.6 13.5 10.6 10.4 15.0 18.1 KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 93.0;Alveolar cells type 2: 27.1;Skeletal myocytes: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.4;SCLC-21H: 33.3;SH-SY5Y: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" 16.8 2.3 16.9 0.9 18.4 0.0 3.7 20.1 32.6 4.3 8.0 9.7 0.9 2.9 1.8 6.2 2.0 1.6 2.1 18.2 17.4 1.2 0.7 13.2 0.3 16.7 16.9 2.5 0.8 0.0 13.9 0.3 17.2 4.3 3.6 8.7 1.8 1.1 28.3 1.0 4.3 1.8 18.0 2.0 5.4 4.0 17.7 0.3 0.9 10.4 0.2 6.0 3.6 19.6 0.0 2.1 10.4 0.0 0.8 1.7 0.0 0.2 1.3 1.1 2.7 0.0 0.0 0.0 0.0 0.2 7.0 0.0 1.0 0.0 1.6 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 4.3 0.0 0.9 0.0 1.2 0.0 0.0 1.2 0.0 4.7 0.0 4.8 0.0 0.0 0.0 2.6 0.0 0.2 0.0 33.3 17.8 0.0 0.0 0.2 0.0 0.0 1.1 0.0 5.3 0.8 0.0 1.9 0.0 0.0 0.0 4.7 0.3 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 18.4 20.1 32.6 18.2 17.4 16.7 16.9 17.2 18.0 17.7 19.6 0.4 93.0 27.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 0.7 0.0 0.3 8.4 0.0 0.0 0.0 0.3 0.3 0.6 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 3.6 1.1 0.0 34.3 0.5 1.0 0.1 0.0 0.0 0.1 0.1 3.4 0.0 0.0 KIAA1217 "DKFZP761L0424, ETL4, SKT" ENSG00000120549 KIAA1217 Q5T5P2 10 23694746-24547848 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 108.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 609.1;Inhibitory neurons: 1251.8;Oligodendrocyte precursor cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 82.6;Karpas-707: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004941 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA004941: AB_2130659" "unprognostic (3.60e-2)" "unprognostic (7.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.45e-3)" "unprognostic (1.60e-3)" "unprognostic (2.03e-3)" "unprognostic (1.87e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.69e-1)" "unprognostic (1.84e-3)" "unprognostic (5.27e-2)" "unprognostic (2.44e-1)" "unprognostic (2.97e-1)" "unprognostic (1.22e-1)" 28.4 16.5 9.8 3.5 12.1 0.2 30.5 2.2 9.6 15.7 42.2 13.1 12.9 6.0 13.3 30.9 16.9 14.7 17.8 27.5 2.0 18.0 17.5 14.4 2.6 6.0 11.2 13.1 13.6 42.8 6.5 20.9 5.7 20.5 14.7 23.7 39.2 22.5 108.4 17.6 11.3 3.3 0.5 7.5 17.4 15.7 4.2 12.6 33.6 52.7 9.3 12.1 19.1 17.2 19.5 9.7 3.8 0.1 2.4 6.8 82.6 3.7 6.0 8.6 18.2 16.6 30.3 1.0 18.6 7.6 17.6 31.5 4.7 36.2 9.5 7.2 3.4 0.4 23.1 19.4 4.2 0.0 0.3 25.3 22.8 19.0 5.2 3.9 0.0 1.7 0.0 75.7 4.4 6.8 10.8 0.6 8.5 18.9 8.7 0.8 22.0 16.2 20.1 25.3 2.4 1.3 9.4 31.4 0.0 38.3 15.2 0.0 20.3 13.1 14.1 52.9 4.9 33.4 30.4 0.1 43.4 0.5 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.8 12.1 2.2 9.6 27.5 2.0 6.0 11.2 5.7 0.5 4.2 17.2 149.7 38.5 34.4 27.4 1.0 121.3 74.1 58.0 145.1 13.6 38.8 39.0 39.1 24.3 73.7 33.1 8.4 50.2 0.4 52.5 3.9 32.3 33.7 64.5 19.6 34.4 23.9 0.0 609.1 26.2 21.2 23.3 50.0 85.9 1.3 6.6 25.0 24.8 5.3 0.0 1251.8 22.8 26.4 14.6 7.8 11.3 17.7 1.3 1.8 30.0 0.0 93.6 0.0 255.9 10.3 24.1 22.7 33.1 3.1 36.8 15.4 6.3 36.9 3.1 13.1 19.6 20.4 0.8 1.1 96.4 51.0 65.1 2.2 14.2 19.4 43.7 KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952730-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4;Excitatory neurons: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 39.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Approved Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA018135: AB_1859551" "unprognostic (1.67e-1)" "unprognostic (1.65e-3)" "unprognostic (1.14e-2)" "unprognostic (1.46e-2)" "unprognostic (7.34e-2)" "unprognostic (3.52e-2)" "unprognostic (8.71e-3)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (2.66e-2)" "unprognostic (7.68e-2)" "prognostic favorable (3.19e-6)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (7.54e-2)" "unprognostic (7.87e-2)" 10.7 13.7 12.4 5.1 13.2 0.8 22.5 2.8 17.9 10.3 8.6 16.0 14.4 6.6 5.2 25.9 20.0 14.8 11.3 20.0 7.7 11.0 34.1 12.2 5.5 6.7 8.3 8.5 10.1 10.3 11.2 4.1 3.9 13.2 14.2 15.5 25.9 15.5 25.1 28.0 16.8 6.8 6.5 3.8 12.4 4.9 13.5 15.6 26.6 22.1 8.9 8.9 18.7 5.6 25.2 15.7 3.3 5.9 0.1 0.1 2.6 0.1 0.1 1.4 0.1 12.6 9.0 0.1 11.7 1.1 6.9 29.8 25.5 25.2 1.0 0.2 10.6 0.1 16.7 16.9 3.3 0.1 1.3 0.6 22.4 7.9 24.3 16.6 28.9 0.5 0.3 0.1 3.4 11.6 0.1 0.1 5.2 39.9 8.3 1.1 26.6 4.9 16.3 10.8 8.0 6.7 20.3 14.0 1.3 10.8 7.6 0.2 19.5 1.4 27.0 16.6 4.5 0.1 0.4 0.1 10.0 0.0 4.3 0.2 0.0 0.0 1.8 0.0 0.2 0.0 0.5 1.3 0.0 0.1 0.2 0.8 0.2 0.4 0.0 0.1 0.1 0.3 12.4 13.2 2.8 17.9 20.0 7.7 6.7 8.3 3.9 6.5 13.5 5.6 27.7 12.8 21.9 74.4 1.1 10.8 21.1 16.2 18.2 4.2 25.4 16.5 11.9 25.8 19.2 5.5 22.9 0.2 3.0 62.9 0.0 18.9 2.6 31.2 3.5 28.5 7.2 5.3 67.8 18.9 0.1 4.9 22.4 30.2 1.3 4.2 29.6 47.8 2.4 16.8 22.9 12.3 6.1 1.9 5.9 3.5 7.2 1.6 10.6 43.1 0.6 21.6 0.0 12.5 3.4 21.4 34.1 9.1 0.6 18.2 34.1 8.8 32.0 17.6 0.0 11.0 9.3 6.8 8.8 27.3 14.5 1.0 6.6 6.6 20.1 29.2 KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 63.3;Microglial cells: 67.5;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 75.6;ASC diff: 11.3;ASC TERT1: 16.9;WM-115: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" 5.6 2.1 18.4 6.0 87.7 0.5 3.4 39.2 42.2 13.1 0.0 9.0 2.4 14.6 6.4 5.1 8.7 16.2 11.4 29.0 64.1 4.1 1.2 2.5 5.0 59.2 62.3 13.6 0.9 0.1 2.2 0.1 54.7 6.6 4.2 0.5 5.8 7.3 0.6 1.4 4.2 14.7 18.3 2.7 3.6 2.6 75.3 8.3 2.0 1.7 4.7 5.2 4.8 105.0 3.0 0.3 75.6 0.1 11.3 16.9 0.0 7.6 4.3 0.0 0.0 0.3 2.2 0.0 0.3 2.4 2.5 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.3 0.0 2.2 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 1.4 0.0 0.0 0.0 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 87.7 39.2 42.2 29.0 64.1 59.2 62.3 54.7 18.3 75.3 105.0 0.1 0.0 0.0 63.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 2.5 0.2 0.0 0.0 0.8 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.4 1.1 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.9 3.7 0.2 1.8 67.5 0.0 0.0 0.0 19.6 135.6 0.6 0.0 7.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 1.1 1.2 0.3 0.3 0.2 0.3 0.0 0.0 0.4 0.0 0.0 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KIF1A "ATSV, C2orf20, SPG30, UNC104" ENSG00000130294 "Kinesin family member 1A" Q12756 2 240713761-240824293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 115.0;pancreas: 34.1;pituitary gland: 42.1;retina: 58.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 393.8;Cone photoreceptor cells: 419.1;Horizontal cells: 536.7;Muller glia cells: 116.4;Rod photoreceptor cells: 176.8" "Cancer enhanced" "Detected in many" "glioma: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 62.5;HAP1: 146.0;SCLC-21H: 276.0;SH-SY5Y: 52.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005442 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Centriolar satellite, Cytosol" "HPA005442: AB_1079210" "unprognostic (1.19e-1)" "unprognostic (2.17e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (1.65e-1)" "unprognostic (4.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-2)" "unprognostic (2.06e-2)" "unprognostic (2.60e-1)" "unprognostic (2.54e-1)" "unprognostic (3.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-3)" "unprognostic (3.90e-2)" 0.2 12.4 54.0 1.1 55.6 0.0 0.1 22.4 113.6 0.1 0.0 2.2 0.7 0.3 0.8 0.0 0.2 0.0 13.7 71.8 25.0 0.2 0.4 0.3 0.0 115.0 47.4 0.7 34.1 0.4 42.1 0.0 107.7 5.4 0.5 58.4 0.2 0.2 0.2 1.0 0.8 0.3 10.2 0.4 2.6 11.2 53.9 0.4 0.9 0.1 0.0 0.1 0.6 99.6 0.0 0.2 1.8 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 3.5 0.4 1.4 0.6 146.0 0.0 0.0 8.4 10.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.3 0.0 2.5 0.3 0.0 8.8 0.0 0.0 0.0 0.6 1.2 0.0 0.0 276.0 52.0 0.0 0.8 0.0 0.4 0.4 0.0 2.0 0.0 1.3 0.4 0.0 0.2 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 55.6 22.4 113.6 71.8 25.0 115.0 47.4 107.7 10.2 53.9 99.6 0.0 0.0 0.0 50.9 0.0 0.9 0.1 0.0 0.0 393.8 0.1 0.3 16.8 0.0 0.0 0.0 419.1 0.0 0.0 0.1 0.0 0.5 2.2 1.1 0.2 1.2 34.2 0.0 57.6 25.1 0.0 2.9 4.1 5.0 0.0 1.5 0.0 0.4 0.1 536.7 72.4 0.8 8.2 0.0 0.4 4.1 0.9 0.1 17.8 9.4 0.0 116.4 0.0 18.1 50.3 14.6 0.0 0.4 0.0 10.4 0.0 0.3 0.0 176.8 0.0 0.0 1.0 46.2 20.5 0.0 0.0 0.0 0.0 3.8 0.1 0.5 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIF26A "DKFZP434N178, KIAA1236" ENSG00000066735 "Kinesin family member 26A" Q9ULI4 14 104138723-104180894 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 22.4;Endothelial cells: 11.9;Enteroendocrine cells: 7.7;Hepatic stellate cells: 13.9;Horizontal cells: 18.5;Spermatogonia: 8.1" "Group enriched" "Detected in many" 5 "stomach cancer: 3.8;testis cancer: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 30.6;MCF7: 24.9;NTERA-2: 20.8;REH: 18.8;SCLC-21H: 19.2;SH-SY5Y: 39.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046882, HPA060346" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046882: AB_2679856, HPA060346: AB_2684259" "unprognostic (3.01e-1)" "unprognostic (3.20e-1)" "unprognostic (3.95e-1)" "unprognostic (1.77e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-1)" "unprognostic (5.49e-3)" "unprognostic (1.69e-1)" "unprognostic (1.21e-2)" "unprognostic (3.31e-3)" "unprognostic (5.24e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.78e-4)" "unprognostic (7.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.12e-2)" "unprognostic (4.68e-3)" 5.0 2.3 2.1 0.7 1.3 2.0 4.6 0.5 1.5 5.0 3.0 2.6 0.4 2.4 0.2 1.4 2.6 0.4 5.7 0.8 1.4 3.8 0.6 2.2 0.3 1.3 1.3 4.1 5.7 0.3 2.9 1.8 1.4 0.8 0.4 0.1 1.0 0.8 2.9 2.8 1.9 0.4 0.9 4.2 1.8 2.8 1.8 0.2 1.5 1.0 0.1 2.0 2.1 0.5 0.0 1.7 1.0 3.9 0.0 0.0 6.7 0.3 0.0 0.0 0.0 3.1 0.0 0.0 5.3 0.0 0.7 2.5 3.1 0.0 0.0 0.0 4.9 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 6.7 0.0 0.0 0.0 24.9 0.0 0.0 20.8 0.2 2.0 18.8 7.9 2.0 0.0 0.0 19.2 39.3 4.4 0.6 0.0 2.5 0.4 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.5 1.5 0.8 1.4 1.3 1.3 1.4 0.9 1.8 0.5 22.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.3 0.1 3.2 0.0 0.0 1.8 0.0 1.0 0.0 1.3 1.9 0.7 0.4 0.2 4.4 11.9 7.7 4.8 0.5 0.2 0.8 2.1 0.0 0.2 0.0 0.4 13.9 0.2 2.6 18.5 0.7 2.6 0.0 0.3 1.1 0.1 0.0 0.1 1.8 3.7 0.0 0.2 0.0 0.0 0.1 0.2 1.0 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.2 8.1 1.2 1.7 0.4 0.1 0.3 2.8 0.0 KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 252.2;Early spermatids: 568.4;Excitatory neurons: 267.2;Inhibitory neurons: 249.1;Late spermatids: 702.5;Oligodendrocytes: 270.7" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" 0.5 5.1 41.3 0.6 17.6 0.0 0.5 13.9 65.2 1.4 0.0 1.1 0.3 0.5 3.7 0.1 0.9 0.1 0.6 28.9 13.7 0.2 0.0 0.2 0.3 15.4 9.0 1.6 2.3 0.3 5.5 0.0 24.6 10.4 0.6 7.8 0.2 2.8 0.3 0.3 0.8 0.4 16.3 0.2 0.6 12.1 49.8 0.1 1.3 0.9 0.2 0.6 1.4 32.0 0.0 0.0 17.8 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.0 0.7 0.0 0.2 5.4 0.0 14.1 0.0 1.3 13.7 3.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.7 0.0 0.7 0.0 0.1 0.0 0.8 0.0 0.0 22.4 0.0 9.2 0.0 0.1 0.1 0.0 3.6 117.1 27.1 0.2 0.5 0.2 2.8 0.0 0.0 0.0 0.0 3.3 0.0 3.7 3.0 0.4 0.0 8.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 17.6 13.9 65.2 28.9 13.7 15.4 9.0 24.6 16.3 49.8 32.0 1.8 0.0 0.0 33.6 2.4 1.3 6.1 0.1 2.2 252.2 8.0 3.7 14.9 4.3 0.0 18.4 108.4 0.0 0.8 1.1 0.0 0.3 568.4 0.9 1.6 6.1 129.7 0.0 267.2 0.0 0.1 4.9 2.0 0.2 0.0 1.1 0.7 0.0 0.2 99.3 249.1 2.7 4.1 0.3 1.9 702.5 8.1 0.8 5.4 10.3 0.8 8.5 2.1 125.2 270.7 0.9 3.4 12.8 1.7 35.8 0.1 0.1 0.0 15.1 6.6 1.6 9.1 15.8 10.7 0.2 0.4 0.0 11.9 0.3 4.9 2.3 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLHL21 KIAA0469 ENSG00000162413 "Kelch like family member 21" Q9UJP4 1 6590724-6614607 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 169.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 104.8;Suprabasal keratinocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 21.4;neutrophil: 63.0" "Lineage enriched" "Detected in all" 8 "granulocytes: 63.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051364, HPA059307" Uncertain Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" Centrosome "HPA051364: AB_2681455, HPA059307: " "unprognostic (6.13e-3)" "unprognostic (5.26e-2)" "unprognostic (2.30e-2)" "unprognostic (9.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.39e-2)" "unprognostic (5.77e-3)" "unprognostic (2.28e-1)" "unprognostic (8.52e-2)" "unprognostic (4.85e-2)" "unprognostic (4.02e-1)" "unprognostic (6.33e-3)" "prognostic favorable (1.71e-4)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (9.74e-2)" "unprognostic (4.19e-2)" 30.5 29.5 31.3 12.6 37.3 25.5 24.6 33.6 35.9 27.2 73.1 44.7 6.9 35.3 8.7 36.4 24.2 14.4 53.3 32.1 31.5 28.2 22.2 16.4 9.2 41.0 44.0 28.6 33.3 21.5 30.1 6.9 37.4 31.7 5.0 7.6 33.3 28.3 169.9 37.0 15.9 16.4 30.7 17.2 30.0 15.2 35.5 9.7 18.7 101.3 7.6 46.5 25.0 44.3 25.8 15.1 7.5 24.3 41.5 25.8 19.5 35.5 28.1 23.0 13.7 44.1 16.1 0.9 30.8 21.9 20.7 41.7 16.6 39.2 12.8 54.8 26.8 29.7 27.8 40.3 34.4 17.8 17.5 28.9 13.0 52.3 17.6 21.6 9.9 14.8 33.3 23.1 19.0 8.9 18.4 15.7 13.8 13.1 55.5 28.0 31.3 32.3 13.5 7.8 30.2 7.5 27.8 22.0 62.8 6.5 14.5 21.0 33.3 74.4 9.1 68.9 86.1 26.2 35.2 18.0 72.2 33.1 28.4 8.4 6.2 21.4 7.1 2.6 6.2 4.5 6.6 7.0 3.8 2.6 5.3 5.3 63.0 2.9 2.3 3.4 8.2 6.1 31.3 37.3 33.6 35.9 32.1 31.5 41.0 44.0 37.4 30.7 35.5 44.3 11.6 3.2 5.1 19.6 8.9 71.2 46.9 22.3 63.2 4.1 47.1 44.4 68.3 7.2 10.7 9.2 4.2 5.1 15.6 10.1 7.9 12.0 2.7 19.6 14.9 15.6 3.0 2.1 8.2 12.9 7.0 24.7 31.1 35.3 0.0 6.4 7.1 23.6 5.6 5.0 8.9 5.6 14.2 10.4 30.1 7.6 10.8 17.1 26.6 8.4 7.6 12.2 4.1 6.6 14.1 20.0 7.3 15.1 12.6 43.1 5.3 7.6 14.0 5.9 13.1 32.2 25.2 2.0 10.9 104.8 72.0 6.4 15.3 9.2 5.5 31.3 KLHL42 "Ctb9, KIAA1340, KLHDC5" ENSG00000087448 "Kelch like family member 42" Q9P2K6 12 27780048-27803040 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Peritubular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020979 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA020979: AB_1852559" "unprognostic (4.68e-2)" "unprognostic (1.00e-1)" "unprognostic (3.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (5.46e-2)" "unprognostic (7.38e-3)" "unprognostic (8.82e-2)" "unprognostic (1.50e-2)" "unprognostic (4.92e-2)" "unprognostic (4.89e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" 8.7 7.3 10.8 11.6 12.1 4.6 9.4 8.3 12.7 11.5 1.6 23.0 8.5 19.0 9.6 13.2 13.4 11.7 6.6 13.2 12.3 7.5 6.4 9.2 9.4 9.2 8.9 8.2 21.3 12.3 9.8 14.1 9.3 14.8 12.1 13.9 6.1 18.8 2.6 9.6 10.0 23.1 9.6 8.7 12.2 10.3 11.3 6.6 10.2 2.6 8.1 21.7 9.7 16.1 11.8 14.9 24.2 22.2 25.9 15.9 23.9 22.5 17.0 16.4 17.6 10.5 16.0 14.6 9.5 14.9 12.6 23.8 11.9 15.6 16.4 19.5 14.5 19.4 29.3 6.9 12.0 17.1 15.2 15.7 12.9 14.3 20.4 21.1 18.7 12.0 6.3 8.0 13.3 10.6 11.9 17.1 34.6 7.6 20.6 13.0 22.1 2.8 9.8 19.2 8.4 24.3 16.6 13.2 17.9 33.8 20.0 15.6 30.2 22.8 13.7 27.7 25.1 9.9 5.5 25.5 14.6 11.2 16.2 0.0 0.5 0.2 1.0 0.4 1.0 0.1 1.1 0.7 0.3 0.5 0.8 1.1 0.0 0.8 0.7 0.7 1.8 0.3 10.8 12.1 8.3 12.7 13.2 12.3 9.2 8.9 9.3 9.6 11.3 16.1 16.2 19.2 16.8 33.0 9.3 23.1 12.3 14.9 29.0 49.8 17.0 25.1 9.1 10.0 12.6 7.3 22.9 69.5 13.9 14.6 3.9 8.9 1.7 9.3 28.8 18.8 27.7 16.8 61.5 20.2 19.8 26.2 15.3 23.9 11.4 25.5 19.2 24.7 13.2 35.3 78.9 12.8 12.2 8.8 11.7 6.0 35.1 8.6 28.4 17.8 16.7 73.9 32.0 63.8 95.5 11.2 7.2 172.3 7.6 14.0 8.0 8.8 7.6 25.2 65.7 33.8 34.6 5.0 12.3 13.1 20.5 20.5 14.7 27.9 11.0 7.4 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9557.9;salivary gland: 5487.3" "Group enriched" "Detected in many" 7 "Exocrine glandular cells: 788.4;Intestinal goblet cells: 1317.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 43.8" HPA059690 Approved "Secreted to digestive system" NA NA 10000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 1.4 2.4 0.1 4.0 0.0 0.4 1.8 0.0 0.4 1.9 0.0 68.8 9.6 2.0 0.0 1.3 0.6 0.1 3.0 0.3 0.0 89.4 0.6 0.5 0.5 0.0 0.0 4.7 9557.9 0.4 0.2 1.1 0.0 2.7 53.0 0.0 5487.3 0.1 0.2 26.3 9.7 2.8 0.0 3.3 1.4 0.1 0.0 0.2 2.9 0.2 1.5 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.4 0.2 0.3 0.5 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 0.1 0.4 0.2 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 0.0 9.7 0.0 0.1 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 9.5 0.0 0.0 0.1 4.0 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 18.9 19.5 1.2 2.9 1.2 0.0 1.0 1.1 0.3 0.0 2.5 0.0 0.0 0.0 0.2 62.2 45.0 3.3 0.6 0.1 1.4 0.4 117.1 0.0 0.0 788.4 0.0 7.7 1.5 0.0 8.9 8.8 0.4 0.0 0.6 0.0 0.0 1317.5 14.2 1.6 5.3 0.3 6.2 1.5 5.4 0.0 6.2 0.0 0.0 0.0 0.0 125.8 134.4 0.0 10.9 9.8 57.1 0.3 0.3 0.0 0.0 0.0 1.1 0.3 0.9 1.7 54.0 0.0 2.1 2.5 148.5 3.8 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Basal respiratory cells: 61.4;Club cells: 113.9;Pancreatic endocrine cells: 74.8;Prostatic glandular cells: 68.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 67.2;HaCaT: 158.7;OE19: 68.1" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 8.6 0.6 0.7 0.2 0.4 0.6 6.2 1.2 0.4 111.8 1.0 1.5 0.3 1.7 0.2 412.5 8.6 3.5 1.3 0.3 1.4 0.6 0.3 8.7 0.0 2.6 1.7 19.7 0.6 0.2 1.5 0.2 2.8 7.2 0.6 0.3 55.2 0.5 0.2 65.7 2.6 0.6 0.7 0.2 1.8 6.0 1.0 0.3 0.6 0.1 18.8 0.6 190.6 0.4 21.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 67.2 0.0 6.6 0.0 0.1 158.7 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 68.1 0.6 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.4 0.3 1.4 2.6 1.7 2.8 0.7 1.0 0.4 0.3 32.1 2.6 0.0 0.0 7.5 15.6 61.4 9.1 1.0 12.3 14.0 0.7 8.6 113.9 0.0 0.0 0.0 0.2 1.2 0.0 7.5 0.3 2.1 1.0 1.7 0.0 0.0 0.1 15.4 0.0 6.0 1.1 8.0 0.0 0.1 1.1 0.0 0.1 0.0 0.6 0.0 22.4 0.0 0.6 0.6 11.5 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.5 74.8 0.0 6.0 0.0 68.6 0.0 0.0 15.8 0.5 0.0 0.4 2.6 1.0 1.6 28.0 4.3 0.0 0.5 0.5 0.0 29.6 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.2;salivary gland: 5.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.5;Intestinal goblet cells: 34.6;Late spermatids: 8.8;Spermatocytes: 15.0;Spermatogonia: 9.5" "Group enriched" "Detected in some" 4 "prostate cancer: 3.5;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.2 0.0 5.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.5 0.0 0.0 0.1 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 34.6 0.0 0.0 0.0 8.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 9.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 40 "Prostatic glandular cells: 777.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 3.5;NB-4: 5.6" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.7 1.1 3.2 1.2 2.3 6.4 0.5 5.2 4.3 0.2 2.2 0.4 1.5 0.6 1.1 0.5 0.3 0.2 0.3 2.6 2.2 0.4 0.8 0.5 1.0 2.2 3.1 0.4 0.0 0.8 0.0 0.2 2.9 566.2 0.3 1.7 1.9 0.4 1.0 0.8 1.0 0.1 0.6 0.7 0.5 3.0 2.4 0.0 1.9 0.0 0.2 0.2 0.0 6.3 0.9 0.6 0.3 0.7 0.0 0.4 3.5 0.2 0.1 0.1 0.1 0.3 0.4 1.0 0.1 0.0 0.3 0.9 0.1 0.0 0.1 0.9 0.6 0.0 0.7 0.0 0.0 0.1 1.7 0.2 0.1 0.1 0.2 0.2 0.0 0.6 0.7 0.9 0.2 1.0 0.6 5.6 0.5 0.9 0.0 0.4 0.0 1.6 0.0 1.1 0.5 0.5 0.1 0.7 0.6 0.1 0.5 0.2 0.4 0.6 1.0 2.6 0.9 0.8 1.8 0.4 1.0 0.6 0.7 0.4 0.6 0.5 0.3 0.3 0.2 0.3 0.2 0.3 0.1 0.6 0.2 0.4 1.7 0.4 0.2 0.5 0.1 0.2 3.2 2.3 5.2 4.3 2.6 2.2 2.2 3.1 2.9 0.6 2.4 6.3 0.0 0.0 0.6 0.0 0.2 0.3 10.2 0.0 0.0 0.0 16.1 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.2 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 777.2 0.0 0.1 0.0 0.0 0.0 0.0 1.8 19.3 7.2 0.0 0.9 0.0 0.6 1.7 0.0 12.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 320 "prostate: 8011.8" "Cell type enriched" "Detected in some" 77 "Prostatic glandular cells: 3438.6" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 173 "BEWO: 31.7;NB-4: 27.8;RPMI-8226: 19.3;SH-SY5Y: 10.5;U-2197: 10.7" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 4.3 7.6 0.0 5.6 0.0 0.0 9.0 0.0 0.0 0.5 0.0 2.6 4.8 1.6 14.4 0.2 4.0 0.0 0.5 0.0 0.0 1.4 1.5 1.2 1.7 0.0 0.0 0.3 0.9 0.6 0.2 0.3 0.0 8011.8 1.1 0.0 4.5 25.0 0.3 0.5 3.7 0.0 0.0 0.2 1.0 6.9 0.0 0.0 0.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 12.4 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.4 2.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.1 9.0 0.0 0.0 0.0 1.8 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3438.6 0.1 0.1 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 4.2 0.2 0.4 44.6 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "prostate: 286.4" "Cell type enriched" "Detected in some" 15 "Prostatic glandular cells: 106.1" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.4;HaCaT: 7.9;OE19: 7.3;SK-BR-3: 5.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.5" HPA051839 Enhanced "Secreted in male reproductive system" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.4 2.9 0.4 1.5 0.3 1.1 1.7 1.7 1.2 6.5 0.0 3.0 7.3 4.4 1.1 2.1 0.6 1.0 0.1 0.3 0.8 0.6 1.2 0.3 0.8 1.6 0.8 0.1 0.9 1.0 0.0 0.3 1.6 286.4 3.6 0.5 4.8 2.7 3.5 8.9 5.1 0.3 0.5 0.3 1.9 1.2 0.6 0.1 3.8 1.3 0.8 1.2 0.2 0.5 4.1 1.6 0.2 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.5 6.4 0.4 0.3 0.1 0.2 7.9 0.0 4.2 0.0 1.1 1.1 1.3 3.8 1.4 0.0 1.4 1.7 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.7 3.3 0.0 1.0 0.1 2.0 0.1 7.3 0.3 0.3 0.4 0.9 0.0 2.6 0.0 0.4 0.3 5.1 0.0 0.2 4.0 0.3 0.9 0.2 0.2 1.0 0.2 2.0 0.9 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 1.2 0.3 0.8 1.6 0.8 1.6 0.5 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.6 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.0 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 106.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 3.3 1.0 2.6 KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 9 "dendritic cells: 642.3;NK-cells: 1855.8;T-cells: 790.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" 3.1 1.7 0.7 17.8 0.8 47.4 5.1 0.3 0.8 4.2 0.2 7.7 10.7 1.6 1.4 3.2 1.5 10.7 0.7 0.6 0.7 1.4 11.3 6.7 20.1 0.6 0.6 1.0 0.4 0.2 0.3 1.4 0.6 2.1 8.1 0.1 0.8 1.0 0.7 0.8 20.1 1.6 0.6 28.9 10.1 0.6 0.6 5.7 1.3 0.9 36.4 10.6 1.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.4 0.2 9.5 2.2 1.1 519.7 2.1 2177.1 1.6 307.4 346.1 1.9 1.5 17.1 98.0 10.5 756.7 3.6 3.9 77.9 285.3 0.7 0.8 0.3 0.8 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.8 6.1 0.0 8.9 0.0 19.0 9.7 0.9 0.0 1.2 0.0 5.2 2.5 1.0 4.3 1.3 0.0 0.0 0.4 642.3 1.7 0.0 0.6 0.0 1.9 1.5 6.2 0.0 118.1 0.4 0.0 0.1 7.9 12.2 2.4 0.0 0.0 45.3 10.1 0.9 0.0 0.6 1.0 0.0 36.2 15.8 0.0 0.0 13.2 24.9 0.0 28.1 0.0 1855.8 2.5 0.1 0.0 3.3 0.0 23.0 1.1 0.9 2.0 0.0 0.0 0.0 1.6 4.1 0.0 0.1 1.2 8.8 1.0 790.5 0.0 2.0 1.3 KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 8 "dendritic cells: 104.2;NK-cells: 254.3;T-cells: 100.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Cell line enhanced" "Detected in some" "HeLa: 5.6;Karpas-707: 1.9" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" 0.7 0.5 0.8 2.2 0.8 5.3 2.0 0.6 1.4 0.7 0.4 1.8 1.4 3.1 1.5 1.4 0.9 2.0 0.7 1.0 1.6 0.3 1.8 3.3 3.1 1.4 1.4 0.7 0.8 0.3 0.3 2.2 1.0 0.7 2.0 1.2 1.2 0.4 0.4 1.0 2.6 0.9 1.2 6.7 4.3 0.9 1.8 1.1 0.7 0.0 2.5 1.0 0.6 2.0 0.2 0.8 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.8 0.0 0.6 0.1 0.0 0.2 1.6 0.1 0.3 1.4 0.5 0.4 0.2 1.0 5.6 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.3 0.6 1.9 0.4 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.1 1.7 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.4 0.0 1.9 0.3 0.2 229.2 0.3 29.1 0.6 0.1 40.1 0.3 0.2 0.3 33.2 6.4 367.6 0.6 0.4 0.1 28.6 0.8 0.8 0.6 1.4 1.0 1.6 1.4 1.4 1.0 1.2 1.8 2.0 1.2 0.0 0.6 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.9 1.3 0.5 1.5 0.0 0.0 0.0 0.1 104.2 0.8 0.0 0.1 1.3 0.3 0.4 0.4 1.8 11.2 0.2 0.0 0.0 0.6 3.1 0.4 0.0 0.0 3.9 0.9 0.1 1.7 0.1 2.8 0.0 4.0 0.4 0.4 0.6 2.0 5.4 0.0 1.4 0.0 254.3 1.0 0.0 0.0 1.2 1.2 17.6 0.1 0.6 0.6 0.0 2.0 0.0 0.1 0.8 1.1 0.6 0.5 0.1 0.1 100.2 0.0 0.5 0.4 KLRC2 "CD159c, NKG2-C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;lymphoid tissue: 5.8" "Group enriched" "Detected in some" 6 "dendritic cells: 111.5;Oligodendrocyte precursor cells: 32.6;T-cells: 49.9" "Cancer enriched" "Detected in single" 8 "glioma: 3.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "gdT-cell: 24.6;NK-cell: 84.5" "Group enriched" "Detected in many" 103 "NK-cells: 84.5;T-cells: 24.6" "Cell line enhanced" "Detected in some" "GAMG: 19.1;HEL: 5.8;HeLa: 17.5;HSkMC: 4.1" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (9.05e-4)" "unprognostic (2.54e-2)" "unprognostic (3.77e-2)" "unprognostic (2.51e-3)" "unprognostic (2.83e-1)" "unprognostic (9.49e-4)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (2.88e-1)" "unprognostic (4.00e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-9)" "unprognostic (8.10e-2)" "unprognostic (2.34e-1)" "unprognostic (8.93e-2)" "unprognostic (5.31e-3)" 0.4 0.1 3.9 0.4 3.8 2.2 0.8 3.6 9.4 0.3 2.8 1.3 0.7 0.9 0.0 0.5 0.5 1.1 0.1 3.7 4.1 0.1 0.8 1.0 1.1 4.2 4.2 1.0 0.2 0.0 0.1 0.4 4.1 0.3 0.8 0.3 0.3 0.2 0.0 0.1 1.1 0.0 4.2 5.8 2.3 0.4 3.9 0.3 0.3 0.0 1.3 0.4 0.3 4.7 0.0 0.9 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 19.1 0.0 0.0 2.2 0.0 0.0 0.0 5.8 17.5 0.3 0.0 0.6 0.0 4.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.1 1.2 0.1 0.4 0.0 0.0 0.0 0.0 0.6 2.8 0.1 0.1 0.0 0.0 0.0 24.6 0.0 0.6 0.0 0.0 11.0 0.0 0.0 0.1 9.2 0.5 84.5 0.1 0.0 0.0 4.6 3.9 3.8 3.6 9.4 3.7 4.1 4.2 4.2 4.1 4.2 3.9 4.7 0.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.3 1.2 0.0 0.6 0.0 0.0 0.0 111.5 0.2 0.0 0.2 0.0 0.1 0.1 0.1 9.6 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.2 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 9.2 32.6 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 49.9 1.7 0.3 0.2 KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "dendritic cells: 19.2;Oligodendrocyte precursor cells: 36.2;T-cells: 15.9" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.4;GAMG: 2.8;HEL: 1.3;HeLa: 7.0;HSkMC: 1.2;SuSa: 1.3;U-698: 1.9" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" 0.2 0.1 1.3 0.3 1.4 1.9 0.1 0.7 2.1 0.1 0.2 0.5 0.8 0.5 0.1 0.2 0.2 0.6 0.0 1.3 1.7 0.1 0.5 0.6 1.7 1.7 1.1 0.1 0.1 0.0 0.0 0.1 1.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.3 4.0 0.6 0.2 1.3 0.4 0.1 0.0 0.8 0.1 0.1 2.1 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 1.3 7.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 7.0 0.0 0.0 0.1 8.7 0.6 63.1 0.0 0.0 0.0 3.6 1.3 1.4 0.7 2.1 1.3 1.7 1.7 1.1 1.2 1.3 1.3 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 0.1 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 1.9 0.0 0.0 1.0 36.2 2.3 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.1 KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Cell type enhanced" "Detected in some" "dendritic cells: 22.2;NK-cells: 8.2;Plasma cells: 4.7;T-cells: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cell line enhanced" "Detected in some" "HeLa: 5.5;SuSa: 1.8;U-698: 1.7" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" 0.8 0.7 2.0 2.3 2.1 1.7 1.5 0.9 2.0 0.6 0.2 1.2 1.3 0.8 0.6 0.8 0.5 2.2 0.3 1.6 2.0 0.2 1.2 1.8 4.7 2.2 1.6 0.4 0.1 0.0 0.1 0.5 1.8 0.4 1.3 0.1 1.1 0.1 0.0 0.1 2.6 0.5 1.2 9.4 2.3 0.6 1.9 0.6 0.7 0.0 3.2 0.6 0.5 2.8 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.3 0.0 0.0 5.9 0.0 0.0 0.0 6.7 0.1 4.7 0.0 0.0 0.0 1.8 2.0 2.1 0.9 2.0 1.6 2.0 2.2 1.6 1.8 1.2 1.9 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.4 0.0 0.0 0.4 0.0 8.2 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.1 KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "dendritic cells: 740.2;NK-cells: 1316.2;T-cells: 324.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 512.6;memory CD8 T-cell: 217.7;naive CD8 T-cell: 218.7;NK-cell: 737.5" "Group enriched" "Detected in many" 68 "NK-cells: 737.5;T-cells: 512.6" "Low cell line specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" 1.6 1.4 1.5 2.8 1.1 8.4 1.8 2.1 2.1 1.2 0.0 1.6 1.8 1.2 1.5 1.3 1.1 1.6 1.1 1.6 0.7 0.8 4.1 4.7 6.8 0.4 0.2 1.1 2.2 0.5 4.6 1.3 0.4 0.6 0.9 1.3 1.3 0.6 1.2 0.9 3.4 0.7 0.1 17.0 2.1 1.2 1.0 0.5 1.2 0.2 4.0 2.1 0.8 3.0 0.2 0.1 0.2 0.4 0.4 0.2 0.2 0.7 0.0 0.0 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.3 0.0 0.2 0.0 0.5 0.5 0.4 0.7 0.1 0.5 0.3 0.2 0.1 0.5 0.1 0.3 0.3 0.1 0.3 0.3 1.2 0.0 0.5 0.3 0.3 0.3 0.2 0.4 0.1 0.4 0.3 0.2 0.3 0.6 0.2 0.2 0.6 0.1 0.9 0.2 0.6 0.3 0.5 0.9 0.4 0.1 0.5 0.5 0.3 0.7 0.2 0.4 1.7 0.8 1.1 512.6 2.0 58.1 0.8 3.5 217.7 1.6 0.8 1.3 218.7 9.2 737.5 1.5 2.1 1.3 163.0 1.5 1.1 2.1 2.1 1.6 0.7 0.4 0.2 0.4 0.1 1.0 3.0 7.4 0.0 10.5 1.3 5.8 0.5 1.2 0.2 0.6 0.7 1.7 1.0 2.7 7.2 1.9 0.0 6.2 1.8 740.2 0.4 0.0 0.6 9.0 1.1 1.2 7.7 0.0 24.0 3.1 0.0 1.0 4.5 10.7 1.8 2.5 0.4 15.0 4.3 0.7 1.7 2.0 0.2 0.0 18.3 1.2 12.6 0.3 7.0 5.4 4.7 5.1 0.3 1316.2 1.5 1.8 0.0 0.0 0.7 91.0 1.3 0.2 1.1 1.5 1.0 0.0 2.2 1.7 1.9 3.5 0.3 0.6 0.8 324.9 0.0 0.3 1.4 KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 4 "dendritic cells: 93.7;granulocytes: 118.9;NK-cells: 164.8;T-cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 390.9;MAIT T-cell: 461.3" "Lineage enriched" "Detected in all" 22 "T-cells: 461.3" "Cell line enhanced" "Detected in many" "HEL: 25.1;NTERA-2: 22.1;U-937: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" 4.1 1.7 2.4 3.8 2.6 3.0 2.5 4.3 2.9 1.3 1.4 1.5 1.0 1.2 2.1 1.0 1.0 3.3 2.0 2.1 3.2 1.4 3.0 2.2 10.4 2.5 3.4 1.0 0.5 0.4 1.1 0.6 2.3 1.1 1.9 1.3 1.6 0.7 1.7 1.0 2.2 1.6 1.7 8.8 1.6 1.1 2.6 2.5 1.0 1.8 5.0 2.4 0.8 3.8 0.2 3.1 1.6 2.3 3.0 0.7 1.4 0.5 0.3 0.4 1.1 1.1 1.1 4.9 0.1 0.4 2.1 0.2 3.3 0.5 0.4 3.6 1.9 25.1 0.4 1.6 0.8 1.1 1.6 1.4 0.4 0.5 0.0 0.4 7.6 2.5 1.4 0.4 0.2 0.7 1.0 2.0 22.1 1.0 1.7 1.2 1.0 0.0 0.5 0.4 0.4 4.4 1.1 0.5 1.6 4.3 0.3 1.7 0.8 0.7 1.0 0.6 1.4 1.4 4.1 2.6 1.8 17.3 0.2 17.5 2.6 1.5 390.9 2.9 461.3 4.2 85.1 237.7 8.2 5.0 23.5 147.7 5.7 20.9 5.4 3.9 8.7 99.7 2.4 2.6 4.3 2.9 2.1 3.2 2.5 3.4 2.3 1.7 2.6 3.8 12.7 0.0 4.3 2.9 4.7 0.4 0.4 0.0 4.0 5.0 1.0 0.9 2.8 1.5 0.1 0.0 8.4 1.0 93.7 0.1 1.9 0.7 1.6 0.8 0.6 2.9 1.2 24.6 3.8 0.2 0.5 1.3 0.5 0.5 118.9 0.9 25.7 2.0 3.4 5.0 3.6 0.1 0.0 9.1 1.4 3.1 0.6 3.7 1.8 2.8 5.4 1.8 164.8 9.5 6.2 0.3 0.1 0.0 16.9 0.2 0.3 3.1 0.1 3.9 0.0 2.1 1.0 7.8 7.3 1.3 0.0 0.3 109.3 0.7 0.6 0.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KPNA3 "hSRP1, IPOA4, SRP1gamma, SRP4" ENSG00000102753 "Karyopherin subunit alpha 3" O00505 13 49699320-49792682 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Viral penetration into host nucleus, Virus entry into host cell" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 145.4;tongue: 94.2" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046852, HPA077643" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046852: AB_2679840, HPA077643: " "unprognostic (4.20e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (3.69e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.03e-4)" "unprognostic (6.27e-3)" "unprognostic (6.79e-2)" "unprognostic (9.40e-3)" "unprognostic (1.56e-2)" "unprognostic (4.57e-3)" "unprognostic (3.93e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.78e-2)" "unprognostic (7.83e-2)" "unprognostic (5.68e-3)" "unprognostic (4.60e-3)" 20.8 10.6 13.6 16.9 15.3 29.7 11.7 14.3 19.6 13.7 9.3 17.0 12.3 13.8 11.3 25.4 12.4 14.6 31.9 16.0 15.0 13.8 23.4 17.2 18.4 14.4 13.5 8.3 10.4 12.6 7.1 14.9 14.3 15.8 16.6 33.4 10.4 19.1 145.4 16.2 12.2 25.6 16.1 13.6 13.4 28.5 15.9 19.9 19.2 94.2 20.2 20.1 11.0 17.8 41.3 28.3 53.0 44.6 53.2 58.1 26.6 73.3 60.8 63.5 46.0 86.2 37.6 89.2 14.4 86.6 42.7 47.1 64.1 59.5 105.2 53.8 44.7 65.3 25.4 101.1 51.8 98.7 40.6 42.9 42.3 53.3 69.8 41.7 79.7 36.9 36.7 23.4 88.8 19.1 53.2 53.7 61.4 57.8 19.7 68.6 52.1 27.3 39.1 33.8 22.2 34.8 27.1 33.3 29.5 43.8 19.8 39.3 73.0 46.7 37.5 43.0 49.8 18.8 27.9 76.7 28.4 44.9 47.2 10.3 3.8 3.6 6.7 4.5 9.3 4.9 6.7 6.6 4.2 2.8 6.4 5.9 2.2 6.7 6.0 2.3 8.5 3.4 13.6 15.3 14.3 19.6 16.0 15.0 14.4 13.5 14.3 16.1 15.9 17.8 44.3 67.3 33.8 64.9 35.2 43.1 30.5 21.4 43.9 29.9 23.4 15.0 76.5 21.5 25.7 12.9 33.3 15.5 31.8 26.0 17.6 49.0 316.7 57.4 35.7 44.2 30.5 39.1 90.6 53.7 17.7 30.0 27.0 40.7 33.0 25.4 30.4 36.2 33.1 52.2 83.9 18.4 20.3 37.3 38.7 168.8 22.1 41.9 19.6 55.3 47.1 49.0 35.0 73.4 85.6 51.7 15.0 50.0 36.9 41.7 14.3 28.1 45.8 65.7 26.3 29.1 32.1 66.1 31.8 52.9 49.9 10.5 38.6 61.9 24.9 33.1 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 2789.9;Basal squamous epithelial cells: 8290.4;Squamous epithelial cells: 4637.9" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "HaCaT: 1156.8;hTCEpi: 1001.5" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" 4.7 0.3 0.1 0.2 0.0 0.7 419.1 0.0 0.1 148.2 0.2 1.1 1.5 0.3 2.2 1156.7 32.4 2.8 0.7 0.1 0.0 0.3 0.6 4.3 0.0 0.1 0.1 0.4 1.4 0.0 1.2 0.3 0.1 182.8 1.6 0.0 140.0 4.1 0.7 1319.5 2.3 0.1 0.0 0.3 1.6 8.0 0.1 93.7 0.5 0.0 77.6 9.5 423.3 0.1 56.4 7.4 0.0 0.0 0.0 0.0 0.7 5.3 1.3 0.3 0.2 5.9 20.2 0.0 1.8 0.6 14.0 1156.8 0.0 41.8 0.2 0.6 0.0 0.0 7.7 1.9 0.0 0.1 4.7 0.0 1001.5 2.2 6.9 2.7 3.4 0.0 0.3 0.5 0.2 3.5 0.1 0.5 0.0 3.9 6.2 0.0 0.0 104.9 3.3 5.9 2.6 0.1 1.1 15.0 1.2 0.3 20.3 0.0 18.6 0.3 2.8 0.3 2.2 0.1 0.1 0.0 8.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 6.1 12.8 10.3 0.0 2.7 1309.8 2789.9 1190.9 8290.4 0.6 577.7 670.3 0.8 5.7 287.5 1.8 0.0 0.7 16.9 18.3 1.9 8.5 117.6 4.1 0.7 22.9 4.8 0.0 0.1 7.5 7.7 21.7 4.6 8.2 2.5 0.0 0.0 0.0 0.4 0.0 0.1 10.3 189.2 0.0 61.7 44.4 1.5 17.2 320.2 0.0 0.0 0.2 0.0 0.0 0.1 14.1 10.5 0.4 88.7 872.9 8.6 0.1 57.7 0.6 0.0 0.4 32.1 0.6 0.8 4637.9 193.6 1.2 21.6 0.1 7.2 906.0 KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1328.6;Cytotrophoblasts: 679.8;Prostatic glandular cells: 2203.0;Syncytiotrophoblasts: 3890.8;Urothelial cells: 1590.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "HBEC3-KT: 9.6;Hep G2: 11.0;SuSa: 7.1;T-47d: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" 0.4 0.0 0.0 0.3 0.0 1.1 15.7 0.0 0.0 6.8 0.0 0.1 0.2 1.1 2.1 6.5 3.0 1.5 0.2 0.0 0.0 0.6 1.0 1.4 0.0 0.0 0.0 0.1 3.6 0.1 2.8 15.6 0.0 20.7 0.0 0.6 147.7 0.4 0.3 172.3 0.2 0.0 0.0 3.0 0.2 21.7 0.0 0.4 0.1 0.4 2.5 4.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 7.1 16.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.3 4.6 1328.6 242.1 0.6 0.0 78.0 27.9 0.4 12.8 390.5 3.7 0.0 679.8 1.1 0.1 1.9 462.9 66.2 49.8 7.8 15.1 7.1 0.0 0.5 0.8 109.3 15.0 0.0 66.4 0.0 0.0 0.0 0.0 63.8 0.0 0.3 0.7 57.0 0.0 0.7 10.6 0.6 3.0 5.4 0.0 5.4 15.8 0.0 0.5 0.3 17.7 1.1 0.7 0.0 2203.0 0.0 0.4 275.0 0.2 0.0 0.0 48.4 62.1 0.7 7.9 8.1 3890.8 7.6 0.1 0.9 1590.3 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4054.2;Club cells: 5757.0;Ductal cells: 6457.0;Pancreatic endocrine cells: 5424.3;Respiratory ciliated cells: 3161.5;Urothelial cells: 7112.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 11 "CAPAN-2: 3623.8;EFO-21: 1450.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" 4.9 3.6 0.0 125.5 0.1 2768.7 22.0 0.1 0.5 810.5 2.0 249.1 34.4 14.2 20.5 677.6 52.6 2223.2 3.1 0.0 0.1 31.6 67.8 76.1 1.1 0.3 0.1 1.1 74.8 7.3 21.2 2.6 0.3 74.5 131.0 0.0 1308.3 13.5 1.2 28.1 157.3 11.9 0.1 82.0 363.9 0.5 0.1 14.2 27.1 0.3 199.1 669.9 480.7 0.1 117.7 35.1 0.0 4.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3623.8 0.2 1450.9 0.0 3.7 236.4 0.0 6.9 0.1 5.3 0.0 30.4 0.0 0.8 0.2 0.0 1.1 0.1 230.4 0.0 12.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.9 80.9 0.2 0.2 0.3 0.3 1.0 20.1 0.1 0.1 2.0 65.3 1.0 0.0 8.4 1.8 0.0 2.9 16.9 0.0 2.9 0.6 4.6 4.7 0.2 0.6 2.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 4.7 0.0 0.0 12.1 0.0 0.1 0.1 0.5 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.1 0.2 0.0 20.8 0.0 15.9 0.3 376.6 4054.2 1.8 0.0 38.1 29.3 0.2 1328.2 5757.0 138.0 0.0 0.8 1.2 315.6 0.0 6457.0 2.0 25.6 4.3 11.5 57.9 11.2 0.0 1837.0 0.3 12.2 237.0 52.3 13.4 0.0 2.2 43.2 0.6 0.0 0.0 264.3 956.2 2.7 0.0 15.8 3.4 34.9 0.0 0.0 60.3 0.0 1.0 0.0 0.0 5424.3 183.4 0.0 1.4 420.6 509.8 1.6 3161.5 0.0 0.0 0.0 337.7 0.0 0.3 51.1 0.0 0.3 7.7 0.0 475.5 7112.9 LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86668507-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 1423.0;skeletal muscle: 2945.6;tongue: 1809.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1825.0" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.7;melanoma: 2.5;prostate cancer: 3.6;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 3.0;hTERT-RPE1: 3.3;SCLC-21H: 4.9;SK-MEL-30: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048955 Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 750000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: AB_2680568" "unprognostic (1.60e-1)" "unprognostic (9.01e-2)" "unprognostic (4.87e-2)" "unprognostic (6.92e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-2)" "unprognostic (7.61e-2)" "unprognostic (2.54e-3)" "unprognostic (3.55e-2)" "unprognostic (4.72e-4)" "unprognostic (3.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.16e-1)" 11.1 1.4 12.8 2.8 39.6 0.4 6.5 29.8 29.0 10.1 0.1 36.2 2.4 15.1 4.9 54.5 17.3 3.1 1423.0 14.7 23.3 2.0 0.8 5.1 0.5 55.5 36.9 6.4 1.3 0.5 2.4 2.7 46.2 38.1 5.3 0.7 20.8 25.2 2945.6 4.8 8.8 23.7 26.4 0.6 9.0 4.7 38.4 0.7 5.2 1809.4 0.3 7.0 10.3 78.4 0.1 0.1 0.2 1.7 0.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.4 0.7 0.0 0.0 0.0 0.9 3.0 0.2 0.0 0.0 3.3 0.0 0.3 0.1 1.0 0.0 0.8 0.2 0.1 0.2 0.2 0.2 0.0 1.1 0.0 0.0 0.6 4.9 0.9 0.2 0.1 2.4 0.7 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 39.6 29.8 29.0 14.7 23.3 55.5 36.9 46.2 26.4 38.4 78.4 1.5 0.0 0.0 1.0 0.0 1.0 0.5 0.2 0.0 1.5 0.2 0.3 1825.0 0.0 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.0 23.4 0.1 0.4 15.5 0.0 0.0 4.5 1.1 0.0 31.5 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.0 2.6 0.0 4.1 0.0 1.2 19.6 11.1 0.5 1.8 1.9 0.0 0.7 0.0 1.5 245.1 0.1 0.0 6.8 0.0 0.3 0.0 0.1 0.1 4.1 39.5 48.0 54.9 1.0 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 LDLRAD1 ENSG00000203985 "Low density lipoprotein receptor class A domain containing 1" Q5T700 1 54007298-54018186 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "fallopian tube: 116.2" "Group enriched" "Detected in some" 9 "Endometrial ciliated cells: 98.1;Respiratory ciliated cells: 329.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 2.2;Hep G2: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA052489 Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA052489: AB_2681850" "unprognostic (6.53e-3)" "unprognostic (2.05e-2)" "unprognostic (2.51e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.59e-2)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-1)" "unprognostic (8.07e-3)" "unprognostic (2.43e-1)" "unprognostic (2.86e-1)" "unprognostic (5.23e-1)" "unprognostic (4.27e-2)" 0.0 1.5 0.2 0.1 0.1 0.1 0.6 0.6 0.2 4.4 0.2 0.1 0.0 0.7 0.1 0.6 116.2 0.8 0.0 0.1 0.1 0.1 0.1 6.9 0.1 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.2 0.1 3.4 0.1 0.2 0.3 0.1 0.0 0.0 0.2 1.4 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 2.2 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.2 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.5 0.0 6.4 7.2 0.0 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.1 0.1 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 98.1 0.8 0.7 20.9 0.0 0.1 0.2 0.0 1.1 0.0 2.1 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 12.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.0 0.0 329.7 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "epididymis: 14.8;testis: 55.1" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4203.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Group enriched" "Detected in many" 5 "cerebellum: 2.6;medulla oblongata: 2.4;midbrain: 1.2;pons: 2.8;thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "CAPAN-2: 39.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 6 "cerebellum: 3.9" HPA045425 Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA045425: AB_10960538" "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (1.88e-2)" "unprognostic (4.20e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.26e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.31e-1)" "unprognostic (5.66e-6)" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-2)" 0.1 0.3 0.2 0.0 0.2 0.0 0.3 2.6 0.4 0.3 0.0 0.0 0.6 0.3 14.8 0.8 1.6 0.1 0.0 0.1 0.4 1.0 0.0 0.4 0.0 2.4 1.2 0.6 0.0 0.0 0.5 0.1 2.8 0.2 0.0 1.4 1.9 0.4 0.0 0.4 0.2 0.1 0.4 0.0 0.9 55.1 2.2 0.0 0.6 0.0 0.7 0.1 0.5 0.3 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.6 0.0 3.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.4 1.3 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 2.6 0.4 0.1 0.4 2.4 1.2 2.8 0.4 2.2 0.3 0.0 0.0 2.6 1.0 0.0 0.0 1.2 8.4 4.6 12.1 1.6 0.9 0.0 0.0 6.4 0.0 4.2 0.1 0.0 0.0 0.0 1.9 968.7 0.8 0.1 0.7 0.0 0.0 1.4 0.7 0.1 0.2 0.0 1.1 0.0 0.6 1.1 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 4203.7 12.8 1.1 0.0 0.0 0.0 1.3 0.0 1.0 0.5 6.8 0.1 13.9 0.0 8.5 0.3 4.3 1.6 0.7 6.6 0.0 0.4 15.6 9.7 0.7 0.0 0.4 0.1 0.1 0.3 4.4 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 80.5;Fibroblasts: 94.2;Hepatocytes: 175.2;Langerhans cells: 66.6;Microglial cells: 129.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "K-562: 114.7;RPTEC TERT1: 52.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 24.3 7.2 5.2 3.9 5.1 5.0 20.6 4.9 6.5 21.5 25.0 5.9 3.9 24.6 6.7 9.2 16.1 14.7 6.9 5.3 12.3 7.8 130.4 22.5 9.5 5.2 5.7 25.0 3.0 2.9 11.7 5.3 5.2 9.0 5.1 2.5 11.9 7.3 2.1 15.1 5.6 18.7 6.3 3.2 13.7 3.9 7.7 4.7 10.4 32.1 5.7 9.1 4.8 5.2 3.3 2.0 2.6 2.9 11.5 10.6 9.0 14.2 8.1 4.8 4.5 1.5 7.6 1.4 10.1 18.0 1.3 2.7 2.2 12.3 12.7 17.2 3.7 18.8 7.9 0.3 7.0 1.4 1.6 29.7 6.8 2.9 10.8 36.2 13.9 1.4 114.7 2.2 22.5 0.9 1.4 0.4 4.2 2.0 0.2 0.4 2.2 0.8 52.3 1.4 1.6 26.3 3.5 1.5 4.0 14.9 5.0 5.0 5.3 4.9 10.0 1.1 7.8 3.0 2.2 0.5 10.2 5.3 4.8 4.5 0.8 1.2 0.5 0.6 0.4 0.2 0.4 0.4 0.7 0.1 0.3 0.5 0.4 0.4 0.7 0.5 1.0 0.7 5.2 5.1 4.9 6.5 5.3 12.3 5.2 5.7 5.2 6.3 7.7 5.2 97.7 0.0 11.3 47.0 2.6 35.3 1.9 3.3 2.2 4.0 3.1 3.3 6.6 11.5 4.2 9.2 0.0 1.6 1.6 0.5 3.9 1.5 1.1 2.0 4.4 80.5 0.0 10.3 20.9 1.1 2.6 94.2 2.6 12.8 1.3 2.6 52.5 175.2 2.0 1.7 21.8 0.8 2.0 6.3 66.6 2.3 34.5 6.1 35.6 129.3 3.4 0.4 2.1 29.1 24.5 1.7 1.9 7.5 2.4 7.5 0.7 6.4 2.6 1.0 0.0 41.1 10.3 1.1 1.2 4.1 29.5 2.6 4.7 3.3 0.8 2.1 LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 1529.6;Suprabasal keratinocytes: 5136.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HaCaT: 3.9;OE19: 3.9" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" 6.1 1.0 0.0 0.0 0.0 0.1 7.3 0.0 0.0 490.5 0.0 1.8 0.0 1.0 0.0 1463.3 0.9 0.0 2.6 0.0 0.0 2.1 3.0 2.6 0.0 0.0 0.0 1.4 2.7 0.0 2.2 0.0 0.0 5.0 0.0 0.0 167.2 0.1 10.2 6695.7 1.7 0.0 0.0 22.0 3.0 4.9 0.0 0.2 2.3 0.0 1.6 1.0 834.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1529.6 6.3 253.5 102.4 0.0 1.2 13.3 0.4 0.0 64.4 1.8 0.0 0.0 0.0 0.3 0.0 0.0 5.4 3.1 0.2 3.2 1.2 0.0 0.0 0.2 0.1 3.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 41.3 12.3 0.0 0.3 44.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 2.1 0.3 0.3 9.3 0.0 0.0 1.3 4.2 7.5 1.9 329.6 5136.5 0.0 1.6 0.4 0.1 14.0 LHX6 LHX6.1 ENSG00000106852 "LIM homeobox 6" Q9UPM6 9 122202577-122229626 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Early spermatids: 77.2;Endothelial cells: 32.1;Inhibitory neurons: 46.0;Late spermatids: 225.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 13.2;K-562: 9.8;NB-4: 18.4;PC-3: 12.3;U-87 MG: 9.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 6.5;basal ganglia: 7.1;cerebral cortex: 7.7;hippocampal formation: 7.2;hypothalamus: 2.2" "HPA047854, HPA058319" Approved Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA047854: AB_2680183, HPA058319: " "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (8.06e-2)" "unprognostic (6.18e-2)" "unprognostic (7.72e-2)" "unprognostic (4.49e-2)" "unprognostic (5.83e-2)" "unprognostic (3.47e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" "unprognostic (9.14e-2)" "unprognostic (5.64e-6)" "unprognostic (1.77e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" 15.9 0.8 10.7 1.9 7.1 0.0 11.8 0.0 6.8 4.5 0.0 3.5 1.1 3.5 0.6 2.1 3.5 2.8 5.9 6.5 9.7 1.6 0.2 3.6 1.0 0.0 0.0 2.0 1.1 0.9 0.3 2.7 0.0 2.5 1.3 0.1 2.3 0.8 2.3 2.7 3.4 3.3 0.2 0.1 2.2 5.6 1.3 0.7 3.3 2.8 1.0 5.6 4.0 3.1 2.7 0.0 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 13.2 3.3 0.0 2.8 0.0 1.1 0.0 1.4 3.6 0.0 0.0 2.1 0.1 1.0 0.6 0.0 2.5 0.6 0.0 0.8 0.0 0.2 0.0 4.7 0.7 9.8 0.0 0.0 2.8 0.0 18.4 2.8 0.4 12.3 0.0 6.2 0.0 2.2 0.0 1.9 0.4 3.3 1.0 3.3 0.5 2.7 0.0 0.8 0.8 1.3 0.0 0.2 0.3 0.2 0.2 9.6 4.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.1 0.0 6.8 6.5 9.7 0.0 0.0 0.0 0.2 1.3 3.1 13.7 0.0 0.0 0.7 0.0 0.1 0.2 3.6 1.8 0.0 1.3 1.5 2.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.2 0.2 0.1 32.1 0.0 2.7 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 46.0 0.0 0.0 0.3 0.3 225.9 1.2 0.1 0.0 5.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.9 2.5 6.7 0.5 0.3 0.0 0.0 0.1 0.0 0.2 LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 11.9" "Group enriched" "Detected in some" 8 "Kupffer cells: 42.3;Macrophages: 38.7;monocytes: 39.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.8;non-classical monocyte: 169.2" "Lineage enriched" "Detected in many" 5 "monocytes: 169.2" "Group enriched" "Detected in some" 8 "THP-1: 1.0;U-937: 1.5" NA NA 94000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.52e-2)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (9.46e-3)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.90e-2)" "unprognostic (8.72e-2)" "unprognostic (1.13e-1)" "unprognostic (8.28e-3)" "unprognostic (8.82e-2)" "unprognostic (3.79e-4)" "unprognostic (2.53e-1)" "unprognostic (9.83e-2)" 0.7 0.5 0.3 8.2 0.3 2.6 0.2 0.4 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.3 0.8 0.3 0.2 0.4 0.3 0.9 1.8 1.1 0.9 0.6 0.1 0.2 0.1 0.2 0.4 0.7 0.3 0.6 0.0 0.2 0.2 0.1 0.0 0.5 0.7 0.8 11.9 0.2 0.0 0.7 0.3 0.2 0.6 1.1 2.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 47.0 36.0 0.0 126.8 0.0 0.0 0.0 0.1 32.6 0.1 0.1 0.1 35.8 0.4 169.2 4.2 0.1 22.7 0.3 0.3 0.4 0.3 0.2 0.4 0.9 0.6 0.7 0.8 0.7 1.1 0.1 0.0 1.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 4.9 0.0 0.0 0.0 0.0 42.3 0.7 0.0 0.0 38.7 0.0 2.8 39.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 32.3;dendritic cells: 37.4;Kupffer cells: 87.3;Macrophages: 73.8;Microglial cells: 30.9;monocytes: 39.6;Plasma cells: 34.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 19 "Daudi: 5.6;THP-1: 2.9" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" 2.5 1.6 0.2 7.0 0.2 1.2 1.0 0.2 0.3 0.6 0.2 2.1 0.1 0.4 0.0 0.7 1.5 0.0 0.9 0.2 0.3 1.2 2.2 7.6 5.6 0.6 0.5 0.6 0.7 0.0 0.9 0.1 0.8 1.1 0.4 0.0 1.2 0.2 0.2 0.1 6.0 2.7 0.7 36.1 1.1 0.2 0.7 0.0 0.8 0.0 0.3 2.1 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.1 0.0 1.4 39.3 0.0 2.3 0.0 1.2 5.6 2.4 0.0 0.8 0.2 0.0 63.7 2.2 0.0 5.5 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.5 0.8 0.7 0.7 1.4 0.9 0.0 2.2 0.0 32.3 0.3 0.3 0.0 0.0 0.0 0.3 0.8 1.0 1.5 2.5 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.1 0.2 0.5 0.0 2.5 0.0 2.5 0.7 15.9 0.0 0.1 0.0 0.0 87.3 2.2 0.0 0.0 73.8 0.0 30.9 39.6 0.3 9.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 2.2 LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.1;lymphoid tissue: 222.2" "Cell type enhanced" "Detected in many" "B-cells: 436.9;dendritic cells: 306.6;Kupffer cells: 216.1;monocytes: 188.2;NK-cells: 510.9;T-cells: 264.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 243.0;NB-4: 171.7;SH-SY5Y: 163.3;THP-1: 127.6;U-698: 260.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (2.90e-3)" "unprognostic (2.89e-3)" "unprognostic (6.34e-2)" "unprognostic (6.53e-2)" "unprognostic (8.72e-2)" "unprognostic (2.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.01e-2)" "unprognostic (1.20e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.36e-11)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (6.08e-2)" 12.5 7.9 26.2 106.9 31.3 112.1 8.2 18.8 35.4 12.1 19.1 11.2 13.6 7.8 2.0 6.4 8.9 17.5 9.8 29.9 22.6 17.3 10.4 24.8 222.2 22.9 22.1 7.1 7.1 3.3 10.7 15.5 22.3 16.3 9.4 1.0 12.9 5.5 3.1 6.7 61.0 9.1 21.8 170.8 20.5 14.0 22.8 111.3 9.3 3.4 149.8 20.3 8.2 23.7 0.8 7.7 92.9 22.9 0.8 2.4 2.3 2.6 1.4 9.4 6.4 4.2 1.9 243.0 20.5 11.6 9.4 3.9 20.4 0.9 2.6 84.3 8.7 72.4 1.8 20.6 17.6 95.2 7.6 22.8 1.0 9.6 0.3 11.0 25.5 16.5 6.7 13.8 10.7 1.3 84.7 171.7 50.3 0.0 4.4 34.6 37.4 43.6 13.1 1.0 111.2 163.3 11.8 0.2 22.2 23.9 0.6 127.6 32.2 12.8 28.1 0.7 3.4 2.9 1.0 260.4 1.4 13.3 22.7 2144.2 601.8 1434.7 368.9 716.3 364.8 688.5 512.2 432.9 609.8 855.0 679.3 496.3 1248.9 553.2 783.9 230.5 664.2 991.4 26.2 31.3 18.8 35.4 29.9 22.6 22.9 22.1 22.3 21.8 22.8 23.7 11.0 0.0 4.6 0.7 436.9 7.5 7.7 20.5 2.2 1.9 5.0 7.2 1.0 4.3 8.6 11.0 4.2 1.6 306.6 1.1 5.9 20.5 18.8 2.3 14.2 23.6 22.2 99.2 18.7 8.9 3.6 10.1 5.6 4.2 53.3 15.7 30.4 2.0 137.6 3.3 2.2 2.1 26.4 216.1 93.9 57.5 3.4 148.0 37.4 12.2 188.2 8.4 510.9 3.5 2.9 19.8 4.7 4.9 154.3 17.7 0.4 3.7 2.4 1.1 6.6 2.9 30.5 7.8 7.5 1.1 6.0 1.5 264.3 4.7 2.5 4.3 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Cell line enhanced" "Detected in all" "BEWO: 135.5;hTCEpi: 251.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 20.1 14.4 25.5 39.8 27.3 53.8 30.9 25.8 22.1 26.4 32.6 34.0 21.2 17.0 7.7 71.8 34.2 21.3 14.3 20.8 27.7 27.7 33.0 46.8 23.2 37.8 34.2 21.6 28.8 27.0 21.9 48.0 32.8 36.7 34.7 25.5 50.7 19.1 18.8 71.5 29.3 15.9 32.7 37.5 30.0 19.2 33.6 21.3 42.0 9.2 17.8 25.7 45.3 33.1 26.6 4.4 17.9 10.0 7.6 8.8 135.5 17.2 8.0 16.9 14.2 22.7 12.2 25.8 29.9 26.0 8.1 52.6 20.9 90.3 10.6 19.1 22.8 18.8 21.1 24.7 11.4 35.1 33.1 14.3 251.5 13.7 41.0 114.5 43.6 20.6 10.7 18.2 23.3 20.9 21.5 12.0 16.7 68.3 6.7 28.1 30.0 14.3 19.6 62.3 22.8 20.4 13.0 82.1 35.1 54.8 68.7 13.9 26.6 15.1 23.5 8.3 16.3 10.0 16.2 22.4 9.6 16.4 6.6 5.8 5.1 40.0 3.1 3.5 5.9 2.0 5.7 4.3 1.9 2.4 5.6 4.4 96.9 6.7 1.4 4.4 15.2 4.4 25.5 27.3 25.8 22.1 20.8 27.7 37.8 34.2 32.8 32.7 33.6 33.1 19.5 32.1 17.9 16.3 5.2 35.9 37.7 24.8 59.2 9.4 18.0 23.2 25.1 10.0 32.6 5.5 20.9 69.8 15.3 39.3 3.9 13.0 1.4 49.6 19.2 22.4 13.2 10.3 6.4 45.0 52.4 7.6 48.9 41.6 23.5 8.6 14.3 7.1 18.2 3.3 11.3 42.8 18.3 8.9 8.2 1.6 4.4 13.8 3.6 16.9 5.4 16.6 2.1 2.5 15.5 25.9 21.2 4.5 6.2 27.1 12.0 10.5 36.3 22.8 19.7 7.5 17.2 15.6 18.4 46.1 39.1 115.5 9.3 7.1 51.7 29.9 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.3;Early spermatids: 107.2;Excitatory neurons: 135.5;Inhibitory neurons: 93.1;Late spermatids: 76.9;Spermatocytes: 61.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;ASC TERT1: 31.4;HAP1: 25.2;HDLM-2: 29.6;HL-60: 29.1;NB-4: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" 5.0 3.1 5.5 2.4 6.5 27.9 5.4 22.2 8.0 7.9 1.0 1.9 0.5 8.5 0.5 0.9 3.7 4.0 6.3 6.4 6.0 8.7 17.7 5.1 2.6 1.9 6.9 3.7 0.5 0.9 6.0 5.3 3.1 1.8 0.6 26.6 0.8 0.7 1.0 0.7 2.1 4.6 2.3 4.6 1.1 7.1 6.9 0.7 4.2 2.5 1.2 3.9 4.6 3.6 0.0 0.6 5.0 0.0 21.3 31.4 0.0 12.8 5.9 5.1 1.1 9.9 0.0 0.0 0.0 4.9 0.1 0.0 25.2 0.0 1.5 29.6 7.8 0.0 0.2 15.6 2.6 29.1 0.2 7.8 0.0 0.5 0.5 1.2 4.1 0.0 0.0 0.0 2.3 0.3 0.0 27.0 4.7 0.3 0.1 0.0 18.7 0.0 2.9 4.1 10.2 0.0 0.0 0.0 0.1 0.3 1.1 15.5 0.0 4.0 1.5 2.1 0.1 4.4 0.0 0.0 0.4 0.0 0.2 18.8 5.2 15.8 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 29.8 0.0 0.2 0.0 0.1 1.2 5.5 6.5 22.2 8.0 6.4 6.0 1.9 6.9 3.1 2.3 6.9 3.6 4.8 22.4 5.8 18.6 0.0 0.8 4.8 0.0 0.0 77.3 10.8 3.4 22.8 8.6 0.6 25.8 2.1 0.4 0.2 0.3 9.8 1.3 107.2 1.9 8.9 1.9 1.8 0.4 135.5 0.2 0.1 4.9 0.0 3.5 0.0 0.1 1.8 21.5 2.5 30.3 93.1 0.5 0.0 5.2 0.7 76.9 4.7 4.2 0.0 9.4 6.5 42.6 0.0 23.1 2.7 0.0 1.2 1.5 0.4 2.0 20.1 26.5 0.7 11.2 13.1 5.0 19.2 61.3 1.3 0.0 0.4 0.7 0.6 3.5 1.1 1.8 LINGO2 "LERN3, LRRN6C" ENSG00000174482 "Leucine rich repeat and Ig domain containing 2" Q7L985 9 27948078-28670286 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.5;smooth muscle: 8.8" "Group enriched" "Detected in some" 29 "Excitatory neurons: 1591.2;Inhibitory neurons: 988.0" "Cancer enhanced" "Detected in single" "melanoma: 0.8" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 9 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 9 "NK-cells: 1.0" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;hTERT-HME1: 1.5;SH-SY5Y: 9.1;U-87 MG: 1.6;WM-115: 4.1" "Low region specificity" "Detected in all" "HPA016633, CAB025361" Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB025361: , HPA016633: AB_1853362" "unprognostic (1.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-4)" "unprognostic (9.86e-4)" "unprognostic (7.55e-3)" "unprognostic (2.67e-6)" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.08e-2)" "unprognostic (2.30e-2)" "unprognostic (1.95e-4)" 0.0 0.4 0.5 0.0 0.8 0.2 0.0 0.0 3.3 0.6 0.0 0.1 0.0 7.5 0.9 0.0 0.4 0.9 0.0 2.9 3.0 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.8 0.6 1.7 0.0 0.6 0.0 2.4 0.0 1.5 0.0 0.1 0.0 8.8 0.1 0.1 0.6 1.7 0.4 0.2 2.9 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.2 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 9.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.5 0.8 0.0 3.3 2.9 3.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 34.6 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 17.5 0.4 4.6 0.2 1.8 0.0 1591.2 0.0 0.1 1.4 0.0 0.9 1.3 29.6 0.0 0.0 0.2 0.0 988.0 0.0 0.0 0.0 0.0 16.4 0.0 0.1 0.0 43.1 0.1 0.9 5.2 17.6 20.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.3 2.8 1.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 LMAN1L "ERGIC-53L, ERGL" ENSG00000140506 "Lectin, mannose binding 1 like" Q9HAT1 15 74812716-74825757 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 31.7;lymphoid tissue: 25.7;prostate: 60.9;salivary gland: 20.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Late spermatids: 2.6;Prostatic glandular cells: 10.9;Spermatocytes: 7.3;Spermatogonia: 2.4" "Cancer enriched" "Detected in single" 45 "prostate cancer: 2.2" "Region enhanced" "Detected in many" "cerebellum: 13.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.4" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.51e-1)" "unprognostic (2.44e-1)" "unprognostic (4.26e-2)" "unprognostic (3.09e-1)" 0.0 1.8 0.0 0.2 0.8 0.0 0.0 13.3 0.5 0.1 0.0 0.1 0.1 0.0 0.3 0.6 0.0 0.0 31.7 0.2 0.1 0.0 0.0 0.0 0.3 2.3 0.7 0.0 0.0 0.0 0.2 0.0 2.1 60.9 0.1 4.2 20.7 0.0 0.1 0.1 0.3 0.0 2.1 25.7 4.6 1.2 0.3 0.1 0.0 0.0 0.1 0.1 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 13.3 0.5 0.2 0.1 2.3 0.7 2.1 2.1 0.3 3.5 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.1 0.0 1.3 0.0 0.0 0.4 7.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 LMOD1 "1D, 64kD, D1" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 513.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5;Leydig cells: 125.6;Peritubular cells: 275.3;Rod photoreceptor cells: 70.2;Sertoli cells: 197.2;Smooth muscle cells: 224.3" "Cancer enhanced" "Detected in all" "prostate cancer: 43.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.8;BJ: 21.3;BJ hTERT+: 34.4;fHDF/TERT166: 17.4;HSkMC: 14.5;hTERT-RPE1: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA028325: AB_10600300, HPA028435: AB_10602180, HPA030097: AB_10601223" "unprognostic (3.84e-2)" "unprognostic (5.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (5.64e-1)" "unprognostic (6.35e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.73e-2)" "unprognostic (3.51e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (1.15e-2)" 157.7 52.5 7.8 28.5 9.7 0.0 75.4 5.7 9.1 161.9 5.5 513.9 25.1 309.5 49.7 135.8 194.7 85.5 31.7 6.2 8.0 11.8 5.1 44.3 7.3 13.6 6.5 72.2 8.4 18.2 5.8 35.3 6.8 165.2 46.9 48.0 21.2 242.5 137.5 43.2 115.5 206.6 5.4 18.5 218.6 17.9 9.1 2.5 39.8 45.7 1.6 368.7 111.9 7.2 0.0 0.1 0.4 1.2 15.8 2.0 1.3 21.3 34.4 1.3 1.5 0.1 0.2 0.0 0.7 17.4 0.2 0.3 0.5 0.0 0.4 0.0 1.4 0.0 0.1 0.0 1.5 0.1 0.1 14.5 0.0 1.0 0.0 54.4 0.1 0.0 0.2 0.2 0.7 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.1 0.4 0.1 0.3 0.0 0.5 0.4 9.5 0.7 0.0 0.0 0.1 0.8 0.3 0.0 0.7 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 9.7 5.7 9.1 6.2 8.0 13.6 6.5 6.8 5.4 9.1 7.2 16.1 0.0 1.1 8.5 0.3 1.3 1.0 0.3 0.0 4.8 1.6 40.8 25.1 0.0 0.0 0.0 135.5 1.7 0.0 0.1 0.0 0.0 2.1 2.6 64.5 5.8 0.0 0.0 0.5 0.6 0.3 20.4 0.5 1.2 0.0 0.7 9.3 0.4 1.0 3.3 1.0 0.0 0.0 0.0 2.3 8.2 125.6 0.9 3.6 3.7 0.0 7.3 0.0 4.0 1.0 0.0 0.0 275.3 0.0 0.9 0.0 0.1 0.9 70.2 197.2 5.2 224.3 1.2 0.5 0.8 2.3 1.2 1.3 2.1 0.0 0.4 LNX2 "MGC46315, PDZRN1" ENSG00000139517 "Ligand of numb-protein X 2" Q8N448 13 27545913-27620529 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040698 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Plasma membrane, Cytosol" "HPA040698: AB_10673138" "unprognostic (4.97e-2)" "unprognostic (1.97e-2)" "unprognostic (3.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (1.12e-1)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (9.27e-3)" "unprognostic (4.21e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.09e-13)" "unprognostic (4.18e-3)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.84e-2)" 3.2 6.7 2.0 3.7 2.3 3.8 6.9 5.1 3.0 4.0 6.5 10.7 14.2 3.0 4.8 10.6 4.6 7.9 8.7 2.4 2.8 7.9 20.5 11.5 4.0 1.7 1.8 4.3 19.6 7.1 3.2 3.7 1.7 6.4 10.5 8.0 9.4 4.8 5.9 6.6 13.4 3.8 1.9 3.1 9.9 12.3 2.4 7.8 9.9 5.9 5.1 6.2 6.7 1.9 6.4 3.5 6.5 7.2 6.7 3.1 6.8 5.6 4.9 5.4 4.9 12.7 12.5 9.6 4.7 4.9 9.8 12.0 11.8 15.0 7.0 6.0 4.9 12.3 7.2 9.3 10.5 6.6 7.6 2.6 22.8 3.8 14.7 15.4 9.9 9.9 3.8 3.6 7.9 7.9 10.0 4.4 7.2 29.0 3.9 9.2 12.7 5.0 11.9 11.1 16.7 3.5 7.6 15.4 10.1 8.0 10.7 5.2 12.6 3.1 4.3 3.1 4.6 3.5 6.3 9.9 2.0 6.3 4.4 2.0 0.3 0.9 0.5 0.1 0.7 0.5 0.6 0.7 0.3 0.5 0.6 0.6 0.3 1.1 0.2 0.1 1.0 0.2 2.0 2.3 5.1 3.0 2.4 2.8 1.7 1.8 1.7 1.9 2.4 1.9 4.5 32.1 27.6 9.8 5.6 25.4 27.7 15.8 23.9 8.9 13.3 7.6 11.4 25.8 11.4 20.2 2.1 1.5 5.5 27.8 3.9 10.2 16.4 11.0 2.7 7.2 10.2 18.9 23.2 14.2 8.1 3.2 11.7 14.7 1.3 10.8 9.3 59.2 2.3 5.0 8.0 17.0 8.2 5.0 7.7 7.3 2.8 2.8 10.6 21.5 2.3 4.4 5.2 3.0 6.7 11.0 23.5 3.4 5.4 16.8 17.8 7.8 15.9 16.3 0.0 3.1 3.5 15.6 17.5 14.8 22.0 3.0 5.5 11.1 11.9 20.9 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Respiratory ciliated cells: 129.6;Spermatocytes: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 8.1;HL-60: 8.9;JURKAT: 7.1;NTERA-2: 7.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" 1.5 0.4 1.6 0.6 2.1 1.4 1.1 1.6 2.7 0.9 2.8 0.5 0.2 0.7 0.3 0.2 5.5 0.3 1.1 1.2 2.1 0.7 0.2 1.0 0.8 2.1 2.5 0.8 0.2 0.3 2.8 0.2 2.2 0.6 0.1 5.6 0.3 0.7 0.4 0.5 0.4 0.2 2.1 0.7 0.4 12.8 1.9 0.6 0.9 0.4 0.3 0.4 0.4 1.8 2.3 0.4 0.5 0.0 0.9 3.0 0.0 0.9 1.9 2.4 2.1 0.1 0.0 1.5 0.1 0.6 3.1 0.0 1.8 0.0 0.8 0.4 5.6 8.1 0.2 0.0 0.6 8.9 1.8 0.9 0.4 0.8 0.0 0.1 1.6 7.1 0.2 0.0 0.9 0.0 0.8 1.1 7.7 0.0 2.6 4.0 0.0 0.4 2.1 0.2 4.0 3.1 0.5 0.3 0.0 0.2 0.0 4.2 0.5 0.4 0.0 0.3 0.1 0.1 0.1 1.9 3.5 0.1 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.1 1.6 2.1 1.6 2.7 1.2 2.1 2.1 2.5 2.2 2.1 1.9 1.8 3.9 3.2 2.6 8.5 1.5 0.4 0.9 5.3 0.0 6.9 0.4 0.9 3.2 0.0 12.9 5.5 37.5 0.2 1.6 0.1 1.9 0.5 137.9 33.8 5.8 3.0 4.2 4.2 15.1 0.2 0.3 5.0 0.5 1.0 1.3 1.0 10.4 0.3 2.4 11.8 12.5 0.4 6.1 0.8 1.2 36.3 10.5 1.2 0.0 3.7 3.8 7.4 0.0 9.5 3.6 0.3 0.0 10.5 0.7 0.4 0.0 3.6 129.6 18.8 0.0 3.6 3.7 104.4 9.2 0.1 0.3 0.5 0.9 1.9 0.2 0.4 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 LRRC9 FLJ46156 ENSG00000131951 "Leucine rich repeat containing 9" Q6ZRR7 14 59919713-60063559 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.4;choroid plexus: 12.4;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 112.6;Excitatory neurons: 28.0;Inhibitory neurons: 18.0;Late spermatids: 75.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040965, HPA041381, HPA077675" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "Nucleoplasm, Nuclear bodies" "HPA040965: AB_2677225, HPA041381: AB_2677444, HPA077675: " "unprognostic (1.01e-2)" "unprognostic (2.00e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-3)" "unprognostic (2.80e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (1.91e-2)" "unprognostic (4.82e-2)" "unprognostic (3.45e-3)" "unprognostic (6.06e-2)" "unprognostic (2.62e-3)" "unprognostic (8.54e-3)" "unprognostic (8.30e-2)" "unprognostic (1.67e-2)" "unprognostic (2.29e-2)" 0.3 0.1 0.9 0.0 1.6 0.1 0.0 1.0 0.6 0.0 12.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 5.2 5.4 0.0 0.0 0.7 0.5 0.0 3.7 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 8.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.0 0.6 1.0 1.7 5.2 5.4 3.7 4.3 1.9 5.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.6 1.5 0.1 0.1 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.7 18.0 0.0 0.0 0.0 0.0 75.8 0.9 0.1 0.0 1.9 0.0 0.8 0.0 5.5 2.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 2.9 0.2 0.0 0.0 0.0 10.3 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 LRRIQ1 "FLJ12303, KIAA1801" ENSG00000133640 "Leucine rich repeats and IQ motif containing 1" Q96JM4 12 85036314-85264457 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 11.1;choroid plexus: 18.1;fallopian tube: 13.7;retina: 8.8;testis: 15.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 185.6;Early spermatids: 423.8;Endometrial ciliated cells: 287.5;Late spermatids: 248.1;Respiratory ciliated cells: 381.5;Rod photoreceptor cells: 257.6;Spermatocytes: 190.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 3.1;SH-SY5Y: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046162 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA046162: AB_10963055" "unprognostic (3.55e-2)" "unprognostic (7.81e-2)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (1.01e-2)" "unprognostic (9.69e-2)" "unprognostic (4.81e-2)" "unprognostic (4.05e-3)" "unprognostic (1.52e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-2)" "unprognostic (6.98e-2)" "unprognostic (1.25e-3)" "unprognostic (3.35e-2)" "unprognostic (6.10e-3)" "unprognostic (1.64e-1)" 0.1 0.7 2.8 0.1 3.2 0.0 1.0 1.9 2.5 1.6 18.1 0.1 0.0 1.4 2.4 0.0 13.7 0.4 0.2 2.9 3.8 2.0 0.0 2.6 0.0 11.1 8.5 0.4 0.3 3.0 1.4 0.0 6.5 1.4 0.0 8.8 0.4 0.7 0.0 0.0 0.0 0.6 6.7 0.1 0.2 15.5 3.7 0.1 2.4 0.0 0.0 0.1 0.1 4.3 0.0 0.3 2.0 0.0 0.5 1.3 0.2 0.3 0.2 0.8 0.2 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.6 0.8 0.2 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.0 0.5 1.8 0.8 0.9 1.5 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.4 0.0 3.1 0.0 1.6 2.5 0.1 0.0 0.2 0.4 0.9 0.1 0.1 1.8 0.5 0.7 0.1 0.0 0.5 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.2 1.9 2.5 2.9 3.8 11.1 8.5 6.5 6.7 3.7 4.3 0.2 3.2 4.8 22.2 0.0 0.4 1.6 12.0 0.0 11.1 2.9 3.2 1.3 4.3 49.2 16.5 185.6 0.1 0.0 0.2 9.8 11.3 423.8 287.5 2.1 1.6 11.5 0.0 24.5 1.3 0.0 1.3 0.0 7.1 1.3 3.9 0.0 0.0 0.1 0.0 4.8 0.3 14.2 0.0 0.3 248.1 4.4 1.2 3.6 2.8 0.0 16.7 0.0 1.5 1.8 1.6 0.1 4.1 0.1 3.1 0.0 6.1 381.5 257.6 13.1 2.4 3.3 190.8 46.3 0.0 0.0 0.1 0.3 0.7 0.2 0.3 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LRRN3 "FIGLER5, FLJ11129, NLRR3" ENSG00000173114 "Leucine rich repeat neuronal 3" Q9H3W5 7 111091006-111125454 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.2;thyroid gland: 19.6" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Bipolar cells: 29.2;Cardiomyocytes: 24.8;Excitatory neurons: 81.2;Inhibitory neurons: 46.5;Leydig cells: 56.2;Oligodendrocyte precursor cells: 61.3" "Group enriched" "Detected in many" 7 "glioma: 17.5;thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 32.5;naive CD8 T-cell: 30.9" "Lineage enriched" "Detected in single" 70 "T-cells: 32.5" "Cell line enhanced" "Detected in some" "AF22: 24.7;BJ: 14.7;BJ hTERT+: 31.0;GAMG: 15.6;SH-SY5Y: 43.9;SuSa: 13.6;T-47d: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043820, HPA046792" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA043820: AB_2678687, HPA046792: AB_2679810" "unprognostic (4.93e-2)" "unprognostic (4.55e-2)" "unprognostic (5.92e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-2)" "unprognostic (4.78e-3)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.84e-2)" "unprognostic (4.85e-3)" "unprognostic (1.08e-2)" "unprognostic (3.29e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (7.23e-2)" 7.2 23.2 11.9 1.2 12.8 0.6 1.7 10.4 14.7 2.5 4.3 0.9 0.4 0.5 2.3 1.3 0.7 1.0 8.0 11.9 10.4 0.4 2.2 7.5 3.0 6.8 8.5 6.3 0.9 0.2 3.0 5.8 8.6 2.6 1.0 6.3 1.2 4.9 4.1 0.3 1.4 0.4 7.7 1.4 0.4 14.9 13.2 10.5 19.6 0.5 3.6 0.8 0.9 8.9 0.0 0.1 24.7 3.1 11.2 4.8 0.1 14.7 31.0 1.4 1.2 0.0 0.0 0.1 0.0 0.0 15.6 0.1 1.5 0.0 3.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.3 0.1 0.0 0.1 0.1 6.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.0 43.9 0.0 0.0 0.0 13.6 24.3 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 2.7 2.0 0.0 0.1 32.5 30.9 0.2 0.0 0.1 0.0 0.4 6.1 11.9 12.8 10.4 14.7 11.9 10.4 6.8 8.5 8.6 7.7 13.2 8.9 0.8 0.0 4.3 47.0 0.8 0.0 0.0 0.0 0.0 29.2 0.6 0.8 24.8 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 1.1 0.3 0.5 1.2 1.8 0.0 81.2 0.0 0.5 13.3 1.5 0.5 1.3 0.0 1.1 0.0 0.8 3.3 46.5 0.0 0.0 0.0 0.4 4.4 56.2 0.2 1.8 7.5 0.8 11.0 1.0 61.3 7.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 3.8 0.0 1.6 1.7 1.1 0.4 0.0 0.1 0.4 10.3 0.5 0.0 0.2 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LRTOMT "CFAP111, COMT2, DFNB63, LRRC51, LRTOMT1, LRTOMT2" ENSG00000184154 "Leucine rich transmembrane and O-methyltransferase domain containing" Q96E66 11 72080337-72096895 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 67.1;testis: 49.3" "Group enriched" "Detected in many" 12 "Early spermatids: 574.9;Late spermatids: 2222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" 5.0 4.5 21.1 2.5 21.8 2.1 8.7 19.5 24.2 8.7 25.1 5.4 3.7 7.2 17.1 3.8 67.1 3.4 3.7 19.1 19.2 11.7 7.9 7.7 3.2 23.0 25.7 8.1 8.9 10.3 8.9 5.4 21.4 9.3 7.7 19.7 4.4 5.4 7.5 5.8 3.4 5.7 23.4 4.0 5.5 49.3 21.0 4.5 11.0 4.6 3.6 4.1 3.8 22.0 3.9 13.7 8.9 6.9 7.3 6.7 2.1 4.4 3.6 4.0 3.5 6.6 20.4 5.1 6.6 7.8 9.6 7.3 6.3 10.8 4.5 9.4 6.2 3.5 6.3 4.8 1.3 3.0 3.9 2.9 5.4 6.0 4.6 6.4 1.5 10.2 4.0 7.8 6.0 13.6 9.0 6.0 4.4 22.8 3.6 10.8 8.6 7.7 15.9 4.7 8.2 6.2 8.7 19.4 10.4 6.1 39.6 3.3 6.5 4.0 5.7 11.3 3.1 8.0 9.4 5.8 4.0 2.5 4.5 1.8 1.7 3.5 2.0 1.9 1.9 3.2 2.1 1.6 1.0 3.5 1.8 1.8 6.1 6.6 1.3 2.8 4.6 1.4 21.1 21.8 19.5 24.2 19.1 19.2 23.0 25.7 21.4 23.4 21.0 22.0 4.6 0.0 1.5 3.3 2.5 2.3 7.5 10.0 1.8 3.5 8.4 7.5 2.2 5.7 10.7 3.7 12.5 12.7 1.4 4.4 11.7 7.5 574.9 84.3 3.0 6.5 1.2 3.6 2.0 2.5 7.7 5.3 4.1 7.2 0.0 2.2 3.6 6.0 3.1 6.7 1.9 10.8 10.2 1.6 2.8 2222.2 14.9 3.3 1.8 1.9 1.4 21.3 4.1 2.0 3.6 2.0 2.5 10.1 5.1 6.8 4.0 19.9 113.1 16.6 6.6 6.1 7.9 90.3 28.1 2.2 2.4 13.1 1.7 2.9 3.4 6.5 LSM11 FLJ38273 ENSG00000155858 "LSM11, U7 small nuclear RNA associated" P83369 5 157743712-157760709 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039587 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies" "HPA039587: AB_10796330" "unprognostic (3.99e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (6.90e-2)" "unprognostic (2.32e-2)" "unprognostic (1.90e-1)" "unprognostic (6.61e-3)" "unprognostic (9.68e-3)" "unprognostic (1.70e-1)" "unprognostic (2.89e-2)" "unprognostic (3.77e-2)" "unprognostic (3.57e-1)" "unprognostic (1.62e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (6.11e-2)" "unprognostic (3.01e-2)" 2.0 2.1 3.6 1.9 3.8 1.7 2.2 3.8 4.8 4.3 0.2 6.4 2.3 5.3 1.5 2.2 3.1 2.3 1.2 4.0 2.3 1.3 1.3 1.8 2.1 2.7 3.0 3.4 1.9 1.8 2.2 2.1 3.0 4.3 2.6 7.1 1.8 4.7 1.4 2.2 2.3 3.3 3.0 1.6 2.3 4.1 2.7 1.8 1.2 1.4 2.1 9.8 3.5 3.0 3.2 2.3 6.2 6.6 2.7 3.5 5.4 4.3 1.9 3.6 4.7 6.9 3.1 7.0 4.9 2.5 2.5 3.7 8.1 4.7 3.9 5.0 7.6 2.9 8.6 4.4 1.0 8.7 3.5 1.6 3.1 4.3 4.4 4.0 5.9 5.7 5.5 3.7 3.9 3.0 4.9 5.1 1.8 2.6 6.9 7.7 7.7 2.9 1.8 2.9 3.6 5.7 2.8 3.8 3.8 4.5 3.2 5.3 4.2 6.9 2.7 4.1 6.9 3.0 2.0 6.9 2.8 8.9 3.1 0.4 0.1 0.0 0.2 0.1 0.3 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.4 0.0 0.0 0.2 0.1 3.6 3.8 3.8 4.8 4.0 2.3 2.7 3.0 3.0 3.0 2.7 3.0 3.6 6.4 4.1 2.3 2.7 3.6 3.5 1.3 2.2 26.1 3.3 2.5 2.2 1.5 3.1 3.7 6.2 2.1 4.7 3.1 0.0 1.7 10.6 0.8 3.7 3.2 3.0 1.3 11.7 0.9 4.8 3.6 2.0 1.6 1.3 5.5 3.9 2.2 2.2 8.4 11.8 2.0 0.0 4.2 5.7 15.7 1.5 2.6 0.0 1.0 3.5 2.2 4.1 1.5 2.4 1.8 6.2 4.1 2.4 3.7 2.1 1.5 1.9 7.8 0.0 4.3 9.1 10.5 10.9 1.9 4.3 1.2 2.8 2.1 5.5 4.0 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 1171.6;Squamous epithelial cells: 1913.0;Suprabasal keratinocytes: 3866.1" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "A-431: 162.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" 1.7 47.6 0.6 0.2 0.6 0.0 20.4 0.5 1.4 297.4 0.5 0.9 0.0 0.3 0.0 2074.3 1.0 1.4 0.8 0.6 0.5 0.3 0.8 0.5 0.0 0.5 0.5 0.5 1.0 0.0 1.0 2.5 0.5 15.3 0.2 0.0 235.4 0.3 2.6 850.4 0.5 0.0 0.5 0.5 12.4 0.4 0.5 4.6 0.4 0.0 75.6 65.2 491.2 0.7 162.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.0 0.0 1.3 0.0 0.2 0.0 0.0 4.0 11.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.2 4.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.4 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.1 3.2 0.0 0.0 0.0 1171.6 9.4 244.9 138.3 0.0 14.8 14.1 0.2 0.0 154.0 1.8 0.0 0.9 0.1 0.4 1.9 1.1 0.0 0.4 0.1 10.7 0.0 0.0 0.3 0.2 5.7 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 22.4 0.0 137.3 0.0 0.0 0.8 163.7 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 2.5 18.9 0.0 1.2 12.2 0.0 0.0 0.6 16.1 0.0 0.0 1913.0 3866.1 8.2 4.0 0.0 0.4 164.6 LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1386.5;Extravillous trophoblasts: 4724.2;Granulosa cells: 998.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 627.1;BJ hTERT+ SV40 Large T+ RasG12V: 888.7;MCF7: 878.7" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" 221.7 248.1 95.6 47.9 99.3 120.5 205.6 94.4 133.8 218.1 89.1 80.1 24.8 143.5 36.9 187.1 157.0 85.9 141.1 117.3 92.8 214.6 614.0 232.2 40.6 101.0 89.9 199.3 58.4 23.1 92.5 88.8 92.1 143.1 15.3 4.8 140.4 47.3 38.4 130.2 79.0 50.2 103.5 218.3 72.7 52.4 96.3 56.5 94.7 37.6 30.3 107.6 159.2 91.8 75.8 114.5 2.4 98.9 147.9 267.8 161.4 174.7 504.5 627.1 888.7 1.8 204.3 19.2 122.0 214.8 75.1 216.2 60.2 102.7 72.5 13.4 17.9 76.0 54.1 75.5 106.3 7.0 45.0 230.3 37.4 96.1 42.3 68.5 37.9 32.2 17.9 248.8 45.1 878.7 49.0 56.9 41.0 439.2 34.5 32.2 0.8 98.4 153.8 82.3 94.8 12.8 142.3 216.1 231.9 96.3 236.8 44.7 7.2 26.9 66.4 73.9 0.9 1.0 4.7 1.9 56.6 27.4 96.7 14.0 124.4 15.4 186.5 565.5 71.2 129.5 137.1 123.6 72.8 160.1 75.8 125.7 34.8 272.7 753.3 7.6 121.3 241.1 95.6 99.3 94.4 133.8 117.3 92.8 101.0 89.9 92.1 103.5 96.3 91.8 318.1 22.4 13.4 3.3 141.6 175.5 427.7 528.1 255.6 8.7 301.7 492.0 4.5 255.9 440.5 46.0 0.0 1386.5 149.6 2.4 23.5 298.8 3.8 13.5 233.3 312.0 29.3 76.6 21.4 22.7 4724.2 295.8 43.3 18.9 53.3 998.5 151.0 314.0 365.9 47.1 13.1 20.1 130.2 104.3 225.3 10.0 289.8 176.4 158.3 26.2 111.5 18.7 436.7 5.5 3.6 196.8 0.6 222.3 121.6 240.5 2.0 212.3 112.8 3.6 144.7 34.9 151.6 1.5 45.1 238.6 117.3 534.3 229.6 99.8 14.4 593.7 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 504.7;Squamous epithelial cells: 811.7;Suprabasal keratinocytes: 2306.1;Syncytiotrophoblasts: 715.8;Urothelial cells: 642.9" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 99.5;MCF7: 114.2;RT4: 108.2;SK-BR-3: 158.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" 1.7 3.5 0.7 1.7 0.8 6.6 32.1 0.6 1.0 259.1 1.4 1.1 0.5 7.6 1.8 1066.8 3.5 1.3 1.3 0.7 0.9 2.9 1.2 1.6 2.6 0.7 0.8 8.9 1.3 1.8 2.3 12.3 0.7 11.9 0.7 1.0 183.3 1.3 2.8 669.3 1.6 0.8 0.7 2.1 3.3 1.1 0.8 12.2 1.2 0.2 131.9 55.0 487.0 0.7 38.6 0.6 0.2 0.6 0.3 0.0 15.3 1.5 3.9 1.4 1.9 0.5 42.5 0.4 1.7 1.1 5.6 99.5 0.2 4.4 0.7 0.0 0.3 0.7 4.5 0.8 0.4 0.0 0.9 1.7 37.2 0.2 0.3 1.7 0.0 3.1 0.2 0.1 0.1 114.2 0.9 0.0 0.2 24.3 8.3 0.5 0.0 0.2 1.0 108.2 0.1 0.3 0.5 158.9 1.8 4.7 17.7 0.1 0.0 0.0 0.7 0.5 0.7 0.6 3.0 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.8 0.0 1.1 0.1 2.9 1.1 2.6 0.0 5.5 4.7 2.1 0.0 0.0 0.3 0.9 1.2 0.7 0.8 0.6 1.0 0.7 0.9 0.7 0.8 0.7 0.7 0.8 0.7 0.9 0.0 1.1 0.0 1.3 504.7 102.5 161.2 111.0 0.7 66.6 38.0 0.6 2.8 72.6 14.7 0.0 96.5 2.1 0.9 1.9 1.6 0.1 4.5 4.4 7.5 0.0 0.4 0.0 0.2 87.2 18.1 3.6 24.5 5.7 0.5 0.0 0.3 14.0 3.3 0.1 2.2 24.4 0.3 139.8 0.0 0.6 23.2 147.7 0.0 0.7 4.5 0.0 0.0 0.2 4.7 0.2 0.4 0.0 40.4 0.3 0.7 5.7 0.5 0.0 1.5 10.5 0.1 0.9 811.7 2306.1 715.8 9.6 0.5 1.1 642.9 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Club cells: 102.4;Glandular and luminal cells: 100.5;Pancreatic endocrine cells: 136.4;Respiratory ciliated cells: 93.4;Urothelial cells: 238.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 98.0;CAPAN-2: 22.2;HaCaT: 66.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" 0.6 2.3 1.4 1.3 0.6 1.0 4.3 1.0 1.4 2.9 0.0 2.7 9.8 0.8 0.7 8.8 0.9 2.9 0.2 1.0 0.3 6.6 0.4 5.4 0.9 1.1 0.7 0.1 3.3 0.4 0.3 0.2 1.4 1.0 3.2 0.6 5.6 2.6 0.1 2.9 11.7 0.3 0.2 0.8 4.9 0.5 0.9 0.6 1.1 0.0 3.5 3.9 3.0 1.3 98.0 0.4 0.4 0.0 0.1 0.2 0.9 0.1 0.0 0.0 0.0 21.6 22.2 13.8 1.0 0.0 0.1 66.9 0.2 0.9 0.0 0.1 0.4 13.0 0.3 0.0 0.0 5.5 0.4 0.0 0.7 0.0 0.1 0.2 0.1 0.3 14.2 6.5 0.1 8.1 0.0 1.4 1.0 19.1 0.1 0.0 0.6 10.5 16.5 6.7 0.3 0.5 0.0 7.5 0.1 0.4 3.9 0.2 0.4 0.2 0.2 0.1 0.2 20.1 1.0 5.0 0.1 0.7 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.1 1.4 0.6 1.0 1.4 1.0 0.3 1.1 0.7 1.4 0.2 0.9 1.3 4.1 70.5 57.4 0.7 6.5 2.8 75.8 11.3 2.8 3.3 22.2 7.5 0.6 24.3 102.4 40.5 2.1 0.8 2.2 16.9 7.9 51.4 2.9 59.6 16.3 4.1 38.7 4.2 1.0 63.8 0.2 5.7 18.3 100.5 12.6 0.4 2.2 0.8 4.4 1.7 2.9 19.5 34.6 0.9 3.8 1.2 2.1 11.0 1.8 0.0 8.4 0.3 1.0 0.0 0.9 136.4 20.4 2.6 6.3 72.8 40.2 17.5 93.4 1.3 0.0 0.8 3.6 0.4 0.6 13.2 4.0 0.3 2.9 0.3 17.5 238.8 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 317.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 41.4;SiHa: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 78.0 51.1 99.3 6.5 102.8 0.1 45.7 89.1 117.7 32.3 83.5 46.5 73.5 119.4 55.0 31.4 98.0 17.3 97.8 93.9 149.1 124.2 317.6 33.0 6.1 143.8 134.2 155.4 10.9 15.6 25.9 11.2 125.9 82.9 16.5 13.9 78.5 155.5 114.6 9.9 79.0 103.3 115.8 2.4 23.7 9.0 145.2 3.8 5.6 65.1 7.1 28.3 25.4 115.8 0.0 1.0 0.1 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 5.4 4.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 8.1 41.4 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 3.5 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.1 1.1 78.2 0.0 0.5 0.6 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 99.3 102.8 89.1 117.7 93.9 149.1 143.8 134.2 125.9 115.8 145.2 115.8 5.9 0.0 4.1 53.5 0.4 5.5 0.4 1.2 1.8 1.4 3.5 22.4 120.6 52.9 1.9 5.5 4.2 0.4 0.0 10.2 62.6 20.1 0.4 26.4 81.6 10.3 0.0 2.7 36.9 2.8 0.5 17.0 16.3 6.0 137.8 69.6 7.5 221.1 1.5 15.2 7.6 6.4 12.2 4.3 3.6 2.1 46.0 1.8 7.2 9.4 0.0 27.2 0.0 11.6 1.3 7.9 7.8 95.2 0.3 0.6 178.8 182.6 11.8 1.0 13.1 2.6 18.4 0.3 0.4 2.3 4.0 0.4 5.5 0.5 10.5 0.5 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 431.3;retina: 154.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 717.2;Excitatory neurons: 571.8;Horizontal cells: 647.8;Rod photoreceptor cells: 562.1;Sertoli cells: 769.2;Smooth muscle cells: 461.2" "Cancer enriched" "Detected in all" 5 "glioma: 48.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 301.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Enhanced Cytosol NA NA 180000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB009792: AB_2137420, HPA022275: AB_1853944" "unprognostic (9.96e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (3.70e-1)" "unprognostic (4.67e-3)" "unprognostic (2.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (7.00e-2)" "unprognostic (4.78e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (8.22e-5)" 30.2 19.4 135.6 10.9 127.6 0.1 17.8 181.9 299.9 14.9 0.0 16.9 2.1 16.6 9.5 13.0 11.5 11.0 25.8 138.9 310.5 4.0 2.2 7.1 2.2 392.1 297.1 7.0 3.6 2.5 16.4 10.0 431.3 20.1 5.3 154.9 7.7 25.4 6.0 13.3 7.1 26.4 222.4 1.3 15.3 12.0 332.9 1.5 8.3 9.6 1.3 26.7 11.4 272.0 1.4 62.8 133.5 48.7 80.9 140.1 0.2 32.6 22.7 29.0 34.5 0.5 1.7 0.1 71.8 108.2 87.9 0.6 73.2 2.8 43.3 0.2 12.3 6.7 22.3 18.3 43.6 0.0 5.1 142.1 9.3 116.7 42.8 25.9 91.6 0.2 10.6 0.3 49.5 0.6 0.1 0.0 36.5 0.0 21.3 0.4 16.4 0.1 2.5 0.1 89.9 63.0 28.9 0.3 14.9 109.7 0.2 6.1 301.6 90.7 44.6 69.4 140.3 8.0 0.4 0.2 98.5 0.1 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 135.6 127.6 181.9 299.9 138.9 310.5 392.1 297.1 431.3 222.4 332.9 272.0 45.6 0.0 2.0 85.5 1.5 31.6 71.3 2.3 5.2 240.3 14.3 34.3 366.0 2.8 11.5 9.2 717.2 1.6 0.6 0.0 0.0 12.9 13.2 75.4 116.8 97.8 77.6 0.0 571.8 3.4 1.4 220.6 6.6 27.7 1.3 25.3 42.1 0.8 6.4 647.8 350.7 0.7 18.3 1.3 28.4 23.4 309.7 10.1 80.0 91.8 0.0 406.1 0.0 131.2 269.3 7.1 0.0 384.8 0.5 22.1 0.1 0.9 48.6 562.1 769.2 85.4 461.2 8.9 8.0 1.9 50.6 4.0 4.2 269.9 0.2 20.0 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Cell line enhanced" "Detected in many" "CACO-2: 59.8;HeLa: 69.2;MCF7: 88.5;OE19: 55.3;RT4: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Microtubules "HPA029712: AB_10600303, HPA029713: AB_10601339" "unprognostic (8.68e-3)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.33e-3)" "unprognostic (4.35e-3)" "unprognostic (6.95e-2)" "unprognostic (3.35e-1)" "prognostic favorable (9.22e-4)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (4.61e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.07e-7)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "unprognostic (3.62e-1)" "unprognostic (6.51e-2)" 2.7 8.4 36.6 4.9 81.2 4.8 13.1 53.0 49.8 6.1 0.6 24.6 29.0 2.4 19.5 15.8 10.0 8.2 1.4 40.2 59.8 32.6 17.2 7.0 1.5 78.0 67.2 1.5 25.1 24.9 12.0 6.8 75.8 20.0 23.2 57.3 20.3 6.4 0.8 17.1 26.6 2.4 43.3 1.8 18.7 27.4 63.0 5.1 16.1 0.2 5.1 12.0 9.6 130.4 25.6 39.2 0.3 0.1 0.2 0.2 40.4 0.7 1.2 0.4 0.7 59.8 26.3 0.1 5.3 0.8 6.7 38.2 11.1 34.6 0.7 0.2 24.6 26.6 69.2 0.5 0.3 26.1 3.0 0.1 31.5 0.2 2.4 1.0 0.2 2.0 18.4 0.6 0.1 88.5 0.2 2.6 5.2 55.3 5.7 0.1 1.0 4.8 23.6 68.4 24.4 5.2 27.4 51.7 0.6 9.1 20.5 2.6 0.5 0.1 1.9 0.4 1.7 4.6 6.4 0.2 0.5 10.1 0.7 2.8 2.3 0.0 0.0 1.6 0.3 1.4 0.5 0.0 5.7 1.6 0.1 0.0 12.2 0.7 3.1 0.0 0.2 0.7 36.6 81.2 53.0 49.8 40.2 59.8 78.0 67.2 75.8 43.3 63.0 130.4 4.0 57.7 51.4 117.2 1.9 28.2 48.7 21.7 33.6 367.0 29.5 18.4 3.0 28.6 42.9 18.4 146.0 33.1 0.7 67.9 31.3 35.8 293.9 30.4 5.9 4.9 117.7 35.1 217.1 49.0 23.1 4.4 42.8 60.8 0.0 1.2 0.7 37.0 16.3 304.5 258.6 81.5 22.4 3.2 8.5 53.1 6.8 6.2 17.8 15.0 3.2 50.9 0.0 26.2 1501.2 37.2 51.9 3.4 4.4 56.6 60.7 81.8 56.0 104.7 19.7 2.0 5.2 37.5 23.4 49.0 30.4 76.2 3.4 2.8 64.2 62.8 MAP7D1 "FLJ10350, FLJ39022, PARCC1, RPRC1" ENSG00000116871 "MAP7 domain containing 1" Q3KQU3 1 36155579-36180849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 286.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028075 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA028075: AB_10603778" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (5.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (6.00e-3)" "unprognostic (2.05e-1)" "unprognostic (3.57e-2)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (8.56e-6)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (9.32e-3)" 67.9 23.2 41.7 41.5 60.7 36.2 47.1 50.7 52.2 38.9 0.4 84.1 18.9 50.0 3.9 48.8 34.8 28.8 122.4 40.8 43.5 21.8 7.7 53.2 25.0 74.7 58.2 24.8 14.7 12.5 36.5 24.0 78.4 39.5 9.4 13.0 33.5 28.2 286.0 71.6 31.4 34.0 23.3 33.5 39.3 12.6 67.3 22.6 33.1 106.5 17.6 62.1 41.2 96.2 104.8 60.3 92.7 58.9 55.6 41.9 68.3 102.3 102.8 105.4 92.5 33.9 104.6 43.8 85.7 93.5 57.7 112.3 38.3 139.1 34.4 74.9 34.4 29.7 42.5 13.2 87.3 44.0 73.3 73.4 38.6 142.6 87.8 81.5 72.9 59.8 29.1 65.3 59.3 21.0 81.6 37.2 84.7 14.7 33.5 83.8 68.4 41.5 53.0 35.7 35.7 68.6 58.7 32.3 79.6 49.7 21.6 30.9 138.3 123.6 94.4 105.5 140.6 64.4 20.6 52.5 105.8 29.7 75.9 0.1 0.4 0.4 0.3 0.2 0.4 0.0 0.2 0.2 0.2 0.1 0.5 0.2 1.4 0.1 0.1 0.2 0.1 0.0 41.7 60.7 50.7 52.2 40.8 43.5 74.7 58.2 78.4 23.3 67.3 96.2 40.6 44.8 14.4 12.1 26.5 143.1 147.3 18.4 47.8 35.4 44.0 26.3 172.6 17.2 17.9 23.9 10.4 48.3 58.2 39.9 17.6 43.3 36.9 32.1 38.6 46.7 10.1 16.2 17.4 27.4 111.3 48.0 29.6 60.1 12.7 56.3 30.7 9.7 69.9 48.8 35.1 14.9 10.2 40.6 125.3 77.1 30.7 65.1 32.0 9.4 35.9 32.3 75.2 9.5 62.3 66.1 29.2 47.8 53.2 98.5 63.0 14.3 10.0 39.8 19.7 51.6 55.8 17.6 16.1 62.7 141.8 130.2 59.8 17.0 19.5 157.6 MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.0;pituitary gland: 35.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.8;Enteroendocrine cells: 32.3;Horizontal cells: 99.3;Rod photoreceptor cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 19.3;HEK 293: 11.0;SCLC-21H: 15.7;SH-SY5Y: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA034780: AB_10670283" "unprognostic (7.82e-2)" "unprognostic (7.62e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (5.80e-2)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (5.23e-2)" "unprognostic (9.19e-2)" "unprognostic (8.57e-3)" "unprognostic (8.78e-3)" "unprognostic (6.33e-3)" "unprognostic (6.77e-2)" "unprognostic (1.72e-1)" "unprognostic (5.29e-2)" "unprognostic (4.75e-2)" 1.4 9.2 54.7 0.3 50.2 0.0 1.4 27.5 67.8 1.4 0.0 2.1 0.2 2.1 0.3 1.2 1.5 0.0 0.4 53.7 35.1 0.7 0.5 0.5 0.0 78.0 27.0 7.0 1.8 2.0 35.2 0.3 84.0 1.9 0.1 9.6 2.8 0.2 0.3 1.5 1.0 0.2 18.6 0.8 1.5 7.1 39.4 0.2 1.0 0.1 0.0 0.3 1.0 49.2 0.3 1.1 4.7 4.1 0.4 0.0 3.7 0.0 0.0 1.0 0.6 2.4 0.8 0.6 1.0 0.0 19.3 0.0 6.6 0.0 0.0 0.3 11.0 0.0 0.4 1.2 0.5 0.0 0.8 0.3 5.5 0.0 0.1 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 3.4 0.8 1.8 1.1 0.7 0.0 0.0 0.1 15.7 19.8 3.7 4.6 0.2 0.9 0.9 0.0 0.0 0.1 0.1 0.6 0.0 1.1 3.1 0.5 0.5 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.2 27.5 67.8 53.7 35.1 78.0 27.0 84.0 18.6 39.4 49.2 0.6 3.2 2.0 6.5 0.1 0.4 1.6 0.5 0.6 57.8 2.3 3.9 2.3 2.8 2.7 0.0 16.7 0.2 0.0 0.5 0.0 3.0 0.6 0.7 1.7 0.7 32.3 0.0 15.6 2.5 1.1 0.7 0.0 1.5 0.0 0.5 0.0 0.3 0.1 99.3 13.1 0.5 4.1 0.0 0.4 1.8 5.9 0.3 7.2 3.7 0.2 11.2 0.0 6.0 3.2 0.7 0.1 0.7 0.1 1.2 0.3 0.7 0.3 26.7 0.0 1.3 1.0 3.4 2.7 0.6 0.6 1.1 0.3 0.5 0.6 0.5 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.3;Excitatory neurons: 510.6;Inhibitory neurons: 412.2;Oligodendrocyte precursor cells: 263.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Cell line enhanced" "Detected in many" "Karpas-707: 71.4;RPMI-8226: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019018 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA019018: AB_1853665" "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" 21.3 2.3 12.8 12.5 37.1 45.3 15.9 27.7 19.4 6.0 0.0 7.7 5.1 5.9 2.0 6.4 4.9 17.4 3.8 20.9 10.0 4.4 3.7 12.9 6.1 3.8 0.5 1.7 3.2 1.9 4.0 7.3 5.7 3.5 7.2 1.7 3.7 2.2 3.2 4.3 4.9 11.2 0.5 8.8 5.5 2.1 1.4 7.9 4.6 7.9 4.4 21.3 6.1 13.4 0.3 5.2 3.3 0.1 49.0 19.6 0.2 0.3 25.1 2.3 8.1 0.1 13.3 18.7 19.2 0.0 51.1 0.2 0.4 0.2 2.8 0.0 3.6 11.4 13.3 0.2 6.4 23.6 14.6 7.3 0.0 9.0 32.5 21.2 52.7 7.6 0.3 71.4 18.7 0.6 1.4 17.9 4.1 0.3 20.7 0.9 0.2 73.7 52.7 29.0 10.0 0.5 1.7 0.1 37.1 1.4 0.0 21.8 0.3 9.0 13.9 0.4 4.2 5.0 0.1 0.2 41.8 38.5 9.1 37.0 28.6 13.2 0.1 41.4 0.0 0.6 0.1 0.2 22.3 0.3 0.4 0.0 40.5 0.3 40.6 11.4 0.0 8.5 12.8 37.1 27.7 19.4 20.9 10.0 3.8 0.5 5.7 0.5 1.4 13.4 113.3 3.2 10.8 15.3 3.2 18.1 0.2 6.9 3.4 2.2 1.7 1.1 3.1 0.0 6.6 3.7 0.0 0.3 9.8 0.1 0.0 0.0 27.8 5.5 1.2 97.9 0.0 5.0 510.6 0.2 0.2 18.5 5.6 11.6 63.3 0.1 2.2 0.3 12.2 3.3 412.2 0.0 4.1 42.4 76.5 16.2 0.6 63.5 12.4 67.5 32.9 3.2 2.1 263.4 9.0 1.3 0.0 0.0 2.4 0.8 0.0 0.5 3.5 3.5 0.0 1.8 2.0 1.8 1.4 0.7 13.4 0.3 3.7 0.3 0.0 0.6 MCTP2 "FLJ11175, FLJ33303" ENSG00000140563 "Multiple C2 and transmembrane domain containing 2" Q6DN12 15 94231538-94483952 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 72.8;NK-cells: 97.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Immune cell enhanced" "Detected in many" "neutrophil: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 20.8;HMC-1: 16.4;U-698: 22.4;U-87 MG: 24.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051176, HPA070541" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA051176: AB_2681373, HPA070541: AB_2686277" "unprognostic (1.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.63e-2)" "unprognostic (7.15e-4)" "unprognostic (3.57e-2)" "unprognostic (2.66e-3)" "unprognostic (3.45e-2)" "unprognostic (3.68e-3)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (5.87e-2)" "unprognostic (4.36e-1)" "unprognostic (1.76e-3)" "unprognostic (9.41e-2)" 4.1 3.8 1.0 6.6 1.8 18.0 2.9 0.0 6.8 5.4 0.8 10.6 6.9 1.8 8.6 3.9 4.1 4.5 0.6 1.1 2.8 2.3 1.5 8.7 6.1 0.0 0.3 1.6 5.7 3.5 7.3 19.3 1.0 5.4 12.2 2.6 5.9 4.1 0.1 3.6 6.4 1.6 0.0 21.1 4.7 1.0 1.3 3.0 5.5 0.4 6.2 6.6 3.7 0.6 3.6 0.0 0.1 0.0 0.0 0.0 2.5 1.9 1.1 0.3 0.1 2.4 4.4 10.3 0.5 0.1 0.1 8.0 0.1 6.6 0.0 2.1 0.8 20.8 2.9 1.2 1.4 4.4 16.4 1.1 7.8 0.1 8.2 0.0 0.0 3.6 0.8 5.9 0.0 0.0 2.0 11.4 0.8 3.6 3.7 4.7 0.1 4.0 0.5 10.7 1.9 0.4 0.2 3.4 1.3 0.8 0.0 0.3 0.2 0.1 1.7 0.0 0.0 12.0 0.3 22.4 24.1 11.1 1.2 6.6 0.8 12.1 6.1 0.2 3.0 3.5 1.7 2.8 0.0 3.6 0.7 2.7 32.1 10.9 0.9 0.3 0.1 1.9 1.0 1.8 0.0 6.8 1.1 2.8 0.0 0.3 1.0 0.0 1.3 0.6 1.1 3.2 18.6 1.0 38.9 4.2 12.9 8.6 22.8 15.6 3.8 4.3 1.1 7.2 13.2 3.7 0.0 17.0 72.8 39.4 0.0 3.4 4.0 6.5 3.4 1.8 15.6 35.7 15.6 4.7 7.3 7.8 5.6 6.6 36.2 0.3 1.4 1.4 9.6 0.0 10.3 43.8 8.2 8.7 2.1 4.8 0.3 11.1 1.8 25.3 4.7 0.1 97.9 0.0 0.7 4.2 24.6 0.0 45.8 14.2 18.1 1.9 8.7 0.6 0.0 2.5 1.6 3.4 2.5 15.0 2.3 24.5 26.6 0.5 21.5 19.6 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Cell line enhanced" "Detected in many" "CACO-2: 139.4;OE19: 158.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 41.4 44.4 13.4 5.2 15.4 0.4 29.9 14.5 18.1 8.0 8.5 7.7 21.7 4.2 6.5 28.6 4.2 15.5 18.6 13.1 17.4 3.6 9.8 8.8 4.2 15.0 19.1 10.8 3.4 19.9 12.5 2.9 18.3 8.4 11.0 30.0 10.3 17.2 34.7 14.4 10.4 7.8 13.4 7.3 23.8 16.1 16.8 5.6 6.7 30.5 4.5 15.3 12.0 13.5 29.0 59.1 1.4 0.0 48.0 44.4 0.1 18.4 47.0 19.2 37.1 139.4 24.9 0.0 46.8 43.4 38.2 29.8 43.4 16.4 20.9 0.0 24.4 0.0 33.8 0.0 61.4 14.3 50.3 49.0 32.3 38.7 26.3 32.1 30.4 0.0 20.4 0.1 26.4 32.7 0.0 16.2 0.0 158.3 23.0 0.0 48.5 27.9 56.8 13.7 5.8 14.9 31.2 45.7 1.0 25.0 0.0 34.5 32.4 11.9 14.1 3.9 0.1 10.9 13.3 0.1 0.0 0.0 35.9 0.0 1.6 0.0 0.8 0.3 16.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 13.4 15.4 14.5 18.1 13.1 17.4 15.0 19.1 18.3 13.4 16.8 13.5 0.9 19.2 12.1 71.8 0.6 1.9 5.1 12.5 6.8 17.1 2.5 0.9 41.0 7.2 12.7 5.5 2.1 0.6 0.5 12.7 1.9 12.3 5.5 0.7 6.8 2.3 0.0 0.0 117.1 9.5 0.9 8.5 62.7 0.2 0.0 11.2 4.2 12.1 7.1 13.5 70.6 4.1 8.2 74.4 25.6 6.5 25.7 16.7 0.0 23.4 5.5 100.6 0.0 123.6 38.6 15.0 4.5 37.2 0.5 5.2 15.2 3.1 7.2 7.5 0.0 4.5 8.3 7.5 2.3 22.3 3.4 0.8 1.8 33.6 8.9 3.3 MEAF6 "C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91" ENSG00000163875 "MYST/Esa1 associated factor 6" Q9HAF1 1 37489993-37514766 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029599 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 35: Glandular cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA029599: AB_10599996" "unprognostic (4.95e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.41e-3)" "unprognostic (4.36e-2)" "unprognostic (3.16e-2)" "unprognostic (9.75e-3)" "unprognostic (2.87e-3)" "unprognostic (4.91e-2)" "unprognostic (2.68e-3)" "unprognostic (3.57e-2)" "unprognostic (4.77e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (3.93e-2)" "unprognostic (5.12e-3)" "unprognostic (2.19e-1)" 37.9 31.4 28.8 18.7 30.5 28.4 39.0 23.9 38.5 42.3 23.5 45.2 19.7 36.7 32.0 37.3 35.6 26.9 25.8 30.5 38.4 32.9 29.5 32.9 29.0 25.9 29.6 41.7 38.9 52.4 67.6 20.9 29.8 66.5 20.3 18.8 43.1 45.1 43.3 46.5 31.8 26.4 23.8 26.7 35.5 38.8 34.2 50.5 31.0 25.1 28.0 41.6 38.7 28.1 56.3 11.2 36.0 37.5 42.3 57.9 32.8 49.0 51.8 57.4 47.4 24.0 48.2 45.9 52.4 41.8 39.0 30.4 47.6 43.0 44.5 75.8 55.6 67.4 17.6 44.5 46.1 59.4 46.2 37.6 72.0 53.7 78.5 31.2 49.5 58.7 89.1 36.4 46.2 23.4 61.9 39.5 69.7 36.4 49.3 60.4 53.4 65.0 42.7 26.6 68.2 38.9 61.8 35.2 73.3 23.0 41.1 41.3 39.4 47.3 36.1 58.5 39.4 58.1 88.0 83.7 43.4 77.8 33.4 108.4 71.1 123.0 97.7 61.3 100.3 102.2 87.6 95.8 73.4 101.8 86.0 79.7 33.3 80.3 70.3 62.3 109.9 114.4 28.8 30.5 23.9 38.5 30.5 38.4 25.9 29.6 29.8 23.8 34.2 28.1 71.4 64.1 47.2 30.0 102.9 211.8 179.3 158.5 84.2 44.0 115.7 81.8 28.1 107.2 98.1 108.5 22.9 88.6 94.0 23.0 223.0 96.0 47.0 127.2 53.3 59.4 70.2 83.5 34.1 63.0 58.3 74.2 47.9 89.7 54.3 67.5 75.3 59.9 88.9 20.2 28.9 60.3 146.5 66.3 125.5 103.2 75.8 61.5 131.6 9.4 81.4 71.2 115.4 28.6 36.9 64.2 35.8 81.6 59.4 251.4 52.8 184.2 174.7 42.5 46.0 52.4 79.2 143.7 197.5 91.8 246.6 53.8 111.6 56.5 52.3 120.4 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MESP1 "bHLHc5, MGC10676" ENSG00000166823 "Mesoderm posterior bHLH transcription factor 1" Q9BRJ9 15 89748661-89751310 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 4.5;prostate: 7.3;skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 52.2;Breast myoepithelial cells: 58.9;Distal enterocytes: 40.1;Exocrine glandular cells: 43.0;Spermatocytes: 41.5" "Cancer enriched" "Detected in many" 4 "prostate cancer: 26.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;HDLM-2: 3.1;HEK 293: 3.0;PC-3: 5.7;SCLC-21H: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069981 Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Nucleoli "HPA069981: AB_2686225" "unprognostic (4.17e-2)" "unprognostic (1.52e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (4.83e-2)" "unprognostic (7.21e-2)" "unprognostic (2.68e-2)" "unprognostic (4.95e-3)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (8.38e-2)" "unprognostic (2.06e-1)" "unprognostic (2.24e-3)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (7.03e-2)" 4.5 1.4 2.4 0.0 2.7 0.1 3.0 1.7 3.5 0.5 0.5 1.4 0.1 0.1 0.0 0.3 0.2 0.0 1.3 2.7 2.1 0.7 0.8 0.2 0.0 1.7 1.5 0.2 1.2 0.2 1.0 0.0 1.9 7.3 0.0 0.2 2.1 0.1 4.5 0.2 0.5 0.0 1.2 0.1 0.5 1.3 2.6 0.0 0.5 0.3 0.0 0.3 0.4 2.0 3.5 1.3 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 1.3 0.0 0.4 0.0 0.2 0.0 0.0 3.1 3.0 0.1 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.1 0.5 0.8 0.0 0.0 5.7 0.1 0.0 0.8 0.0 0.0 2.6 0.1 0.7 1.1 0.8 0.0 0.0 0.4 0.0 0.0 0.2 2.0 0.6 1.3 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.7 1.7 3.5 2.7 2.1 1.7 1.5 1.9 1.2 2.6 2.0 1.7 0.0 1.1 2.6 2.9 0.3 2.8 5.1 0.6 11.6 52.2 58.9 6.3 17.2 33.9 1.8 10.4 3.0 3.2 40.1 11.7 18.6 5.3 0.3 0.3 2.1 6.1 3.0 2.8 43.0 0.2 3.5 0.5 0.9 4.5 22.1 4.2 12.8 2.0 8.4 3.0 7.4 12.2 1.6 2.1 2.1 1.2 2.5 7.2 1.0 2.1 19.2 2.1 1.5 1.7 4.8 17.9 0.0 4.6 35.7 7.2 16.2 8.7 20.6 0.0 4.0 3.7 41.5 21.7 2.0 0.3 0.3 2.2 18.0 15.5 6.2 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 270.4;skeletal muscle: 310.5;tongue: 337.6" "Cell type enriched" "Detected in all" 7 "Cardiomyocytes: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB079902: AB_2724683, HPA030554: AB_10603018" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-2)" "unprognostic (8.36e-2)" "unprognostic (9.71e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (3.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.43e-1)" "unprognostic (3.55e-1)" "prognostic favorable (2.36e-8)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" "unprognostic (8.84e-3)" "unprognostic (2.12e-1)" 34.7 31.4 39.9 20.9 42.4 26.7 31.8 39.1 41.4 29.3 17.4 59.7 41.9 37.0 12.7 57.3 26.2 21.8 270.4 34.7 43.0 36.5 58.5 31.1 19.8 41.1 44.8 27.0 22.5 76.7 28.7 27.6 40.6 36.3 38.1 35.0 32.2 62.3 310.5 58.9 46.3 41.2 43.5 31.5 44.9 25.4 48.8 26.1 56.1 337.6 30.4 51.2 36.2 40.5 93.6 54.0 52.6 72.7 59.7 47.2 58.8 76.0 66.1 96.5 72.6 88.7 51.8 68.8 74.8 92.6 60.6 80.5 101.7 156.1 90.6 60.6 75.4 94.5 81.8 54.2 53.8 114.2 51.9 57.0 105.1 133.1 124.5 40.1 66.2 26.4 106.1 53.6 69.7 30.2 60.2 15.2 39.7 57.8 77.4 68.2 95.8 58.5 44.9 61.4 68.2 44.6 88.4 81.0 74.6 41.4 43.8 49.2 71.2 63.1 58.3 88.4 71.2 59.0 86.4 120.7 69.0 99.6 69.8 10.4 11.5 7.6 8.9 14.0 10.2 6.7 6.7 7.9 9.7 4.8 5.0 6.2 16.2 6.2 18.3 4.2 8.1 15.7 39.9 42.4 39.1 41.4 34.7 43.0 41.1 44.8 40.6 43.5 48.8 40.5 18.1 22.4 15.8 16.6 10.2 22.8 9.4 18.9 19.9 26.7 17.4 16.4 336.9 7.2 14.9 14.7 12.5 15.1 12.5 39.2 21.5 13.6 4.7 8.9 12.1 18.5 18.0 32.4 21.5 20.4 15.5 17.3 17.3 12.8 10.8 12.8 11.7 46.3 16.0 30.3 24.5 22.2 18.3 23.9 9.7 8.0 7.2 19.1 17.8 8.4 17.3 14.6 8.2 11.1 16.7 18.5 16.8 15.1 10.9 13.9 41.8 14.3 12.9 21.0 13.1 16.0 16.5 25.9 15.6 25.1 30.1 25.2 10.3 12.5 26.4 16.6 MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" 8.4 22.6 9.2 3.4 8.0 1.8 10.7 7.2 12.0 8.0 6.4 22.6 13.5 8.3 4.1 16.1 8.4 2.5 21.8 8.8 6.7 27.5 44.6 7.6 2.8 10.8 7.1 6.7 18.8 12.3 17.8 1.5 9.4 19.2 3.3 1.5 19.6 5.4 23.5 17.8 15.4 1.2 5.4 10.8 15.6 6.3 9.5 2.3 23.9 6.1 1.7 9.7 9.2 7.0 16.2 21.7 5.4 4.6 5.9 4.4 17.6 5.1 5.3 2.8 4.2 7.3 11.2 23.3 17.3 4.8 5.6 15.5 2.5 12.1 0.5 11.0 44.0 7.5 19.9 18.3 11.0 3.6 9.9 6.5 22.3 1.8 7.7 12.1 7.3 16.0 14.2 6.2 6.8 53.7 9.0 18.9 14.3 22.9 36.9 9.9 2.8 41.7 13.2 9.5 39.1 19.7 13.0 31.6 11.3 3.4 33.1 5.2 7.9 3.7 9.9 4.2 7.1 6.0 2.6 8.1 8.0 11.3 6.5 1.8 7.4 3.8 3.9 6.7 3.7 4.9 3.9 4.0 11.0 2.5 3.5 3.6 0.4 3.8 3.6 19.2 4.4 4.1 9.2 8.0 7.2 12.0 8.8 6.7 10.8 7.1 9.4 5.4 9.5 7.0 3.0 3.2 3.7 6.5 8.0 6.0 10.3 17.3 8.6 8.2 18.8 14.5 9.3 30.0 11.8 27.6 10.4 16.5 3.7 31.3 37.2 17.6 0.6 5.1 3.9 3.8 19.8 8.2 6.2 21.0 15.0 4.0 16.3 7.4 0.0 9.7 3.3 27.6 15.5 16.8 6.2 19.6 24.4 7.0 3.2 1.8 4.4 6.4 8.8 1.9 7.5 14.8 6.2 2.5 3.8 15.7 19.1 4.9 14.8 12.8 33.1 63.6 3.2 10.0 0.0 7.0 3.4 3.8 11.7 19.0 7.1 9.3 3.5 16.9 27.1 9.8 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" 9.6 5.8 8.2 9.3 14.8 6.2 10.2 15.7 10.3 18.4 8.0 38.6 6.4 28.4 3.1 46.6 13.6 6.4 10.7 8.7 9.8 8.7 7.0 11.7 5.9 19.7 16.8 4.8 18.5 10.6 4.4 17.3 17.4 17.0 4.6 0.8 17.8 24.0 10.8 36.6 12.5 19.7 14.1 7.2 44.0 10.8 15.3 5.4 10.0 5.2 7.1 25.4 26.0 22.2 25.4 13.7 13.0 15.4 10.4 11.9 59.9 32.3 17.5 34.8 25.3 17.3 13.1 10.8 10.5 22.2 22.7 65.0 9.1 69.9 17.2 21.2 31.3 5.7 11.6 16.7 24.0 11.6 11.8 11.3 101.2 42.5 70.1 10.4 22.1 4.9 8.9 8.1 22.7 10.6 2.9 6.7 5.0 12.9 12.1 16.6 27.4 6.1 8.1 53.0 9.6 8.5 19.3 19.7 20.2 15.4 10.8 10.9 34.3 61.1 47.3 37.8 27.5 9.4 3.7 7.2 55.2 5.8 29.0 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.3 0.5 0.3 0.5 0.3 0.2 0.5 0.5 0.1 0.6 0.1 0.4 8.2 14.8 15.7 10.3 8.7 9.8 19.7 16.8 17.4 14.1 15.3 22.2 10.9 0.0 7.8 1.3 4.8 7.5 10.1 12.8 23.9 0.7 7.3 7.9 11.9 7.2 9.5 5.5 0.0 31.0 7.8 7.7 1.9 10.5 18.1 11.3 5.4 12.2 3.5 1.3 0.7 10.2 26.3 4.3 27.5 6.8 1.3 5.8 6.4 5.9 8.7 5.0 4.4 3.9 6.1 4.4 3.4 28.8 1.8 4.3 1.8 1.0 7.2 0.7 7.2 2.5 17.8 15.4 2.2 4.1 6.4 13.6 4.4 2.7 6.0 0.7 0.0 3.5 9.4 5.5 2.2 27.2 9.1 39.4 5.2 1.5 3.7 15.2 MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 14 "OE19: 1667.9;SK-BR-3: 502.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "HPA056650: , HPA061344: AB_2684484" "unprognostic (2.48e-1)" "unprognostic (3.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (8.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-3)" "unprognostic (2.22e-3)" 29.1 35.9 33.4 17.5 35.4 27.0 31.5 36.2 44.8 31.1 34.2 42.4 26.3 29.0 14.6 47.3 27.2 12.1 49.5 32.5 35.3 57.2 53.7 29.6 20.2 34.5 34.8 18.5 40.7 21.6 39.6 13.5 34.5 46.3 12.8 4.8 46.2 13.8 47.2 35.0 37.5 9.5 32.9 36.2 48.5 41.3 35.4 13.9 37.0 5.3 13.7 31.0 32.0 37.2 38.8 59.7 13.4 34.5 16.3 12.0 16.2 40.7 21.4 24.2 23.6 12.9 27.2 28.1 55.5 15.1 39.0 47.1 15.6 13.8 8.2 58.2 65.8 26.5 29.8 36.5 28.2 33.9 39.2 10.8 23.3 11.7 12.0 18.8 15.6 52.9 38.2 48.9 14.7 22.5 70.1 38.2 12.5 1667.9 26.4 32.2 23.6 56.8 12.2 21.8 43.6 41.7 40.8 502.3 70.7 12.0 66.1 48.1 41.5 16.4 41.8 78.9 47.1 62.3 62.8 55.1 64.5 41.1 32.4 138.5 76.2 107.3 80.1 100.9 43.4 109.2 56.2 72.3 54.5 88.3 43.9 63.1 132.9 58.7 104.2 79.4 94.6 119.9 33.4 35.4 36.2 44.8 32.5 35.3 34.5 34.8 34.5 32.9 35.4 37.2 59.8 44.8 64.2 7.8 60.9 60.2 138.1 185.1 95.6 25.7 127.0 114.2 59.6 82.9 129.3 99.3 4.2 150.2 69.1 226.6 303.3 137.0 136.2 81.6 48.7 58.9 188.8 72.0 11.0 176.1 74.4 50.9 76.5 77.3 81.8 43.8 54.7 118.9 148.0 35.3 9.6 178.3 254.3 101.3 42.8 76.7 42.3 81.3 138.7 12.2 80.1 90.7 130.7 4.5 20.8 216.8 283.7 49.7 54.0 194.8 188.5 224.9 122.1 17.3 46.0 31.5 61.1 108.5 68.0 131.7 70.3 266.1 65.4 51.7 128.1 204.0 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Collecting duct cells: 12.9;Endometrial ciliated cells: 36.7;Endometrial stromal cells: 8.9;Respiratory ciliated cells: 18.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 6.7 3.7 2.1 1.2 3.5 2.4 4.4 0.4 4.2 5.7 10.6 4.6 1.3 5.4 8.4 2.9 11.5 5.6 4.7 1.9 1.8 4.9 2.1 9.5 1.2 2.8 4.5 8.9 3.4 4.8 5.6 3.3 2.2 5.9 2.1 2.1 3.1 8.1 2.3 3.2 2.2 5.9 1.8 1.2 3.2 9.0 2.4 1.2 6.7 3.5 0.9 4.3 3.7 2.5 2.4 6.0 3.1 9.5 2.7 10.3 4.5 3.5 6.0 2.6 2.2 0.0 4.4 0.0 3.9 2.3 3.6 2.6 2.1 2.0 2.5 0.0 3.5 1.9 3.2 0.0 3.3 2.7 1.3 5.3 3.1 7.7 1.5 0.2 3.8 1.7 19.2 1.1 2.2 0.0 1.5 0.8 8.9 8.5 1.4 0.4 0.0 0.6 7.1 1.2 5.7 7.7 2.3 12.5 1.3 3.5 6.4 2.0 2.3 0.1 1.4 2.7 1.5 2.5 3.5 0.0 4.9 0.1 11.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.1 3.5 0.4 4.2 1.9 1.8 2.8 4.5 2.2 1.8 2.4 2.5 5.2 9.6 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 1.8 12.9 0.0 2.3 0.5 0.0 3.9 2.8 0.0 36.7 8.9 2.3 0.0 0.0 0.0 1.3 4.1 2.7 0.0 3.9 2.5 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.4 18.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.2 4.1 0.0 0.0 MIOS "FLJ20323, MIO, Sea4, Yulink" ENSG00000164654 "Meiosis regulator for oocyte development" Q9NXC5 7 7566875-7608932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042928, HPA052223" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA042928: AB_10795610, HPA052223: AB_2681768" "unprognostic (8.09e-3)" "unprognostic (1.25e-2)" "unprognostic (6.93e-2)" "prognostic favorable (6.51e-4)" "unprognostic (3.42e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (1.44e-2)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.28e-6)" "unprognostic (1.03e-1)" "unprognostic (1.10e-2)" "unprognostic (7.67e-3)" "unprognostic (2.72e-1)" 10.0 9.5 7.0 15.2 6.6 18.8 14.5 12.1 8.7 12.3 26.8 11.3 8.8 9.9 10.4 22.9 10.8 9.9 11.9 5.7 9.3 12.6 17.3 11.7 22.4 6.7 7.4 13.3 17.3 28.1 8.9 11.6 6.1 21.7 13.0 18.8 13.5 11.2 85.5 18.1 9.3 12.2 6.7 15.3 13.4 19.2 7.2 16.2 9.3 51.1 29.9 13.9 14.3 8.2 42.4 18.8 21.8 26.4 17.1 35.9 18.3 32.9 26.8 20.6 20.6 23.2 16.5 37.1 9.9 19.7 55.3 37.6 23.1 24.2 27.0 14.8 19.5 9.5 22.5 16.1 24.3 40.1 10.2 30.9 29.0 18.3 46.2 20.1 18.2 12.4 47.2 29.4 88.0 29.1 9.2 17.0 45.3 21.3 19.8 27.4 33.4 36.3 19.0 21.3 23.0 37.2 17.7 49.1 19.3 40.5 26.7 35.1 15.7 31.3 33.2 17.4 27.7 25.9 30.9 33.2 27.6 23.0 37.2 0.0 5.4 8.8 4.3 9.9 3.6 10.1 4.6 4.2 7.6 8.8 6.0 4.9 0.6 5.4 5.0 4.5 5.1 4.0 7.0 6.6 12.1 8.7 5.7 9.3 6.7 7.4 6.1 6.7 7.2 8.2 8.2 9.6 11.9 18.6 30.3 12.1 14.8 6.6 15.4 8.2 13.2 10.8 18.2 12.8 9.2 7.3 12.5 16.8 12.2 9.0 17.6 11.7 38.5 22.7 11.4 7.5 4.2 15.6 22.9 17.5 8.7 9.3 16.3 18.6 9.5 15.4 6.8 17.0 15.5 11.8 21.0 7.2 4.1 22.7 12.2 57.9 5.9 18.4 7.2 27.2 10.1 9.4 13.4 23.1 18.2 14.1 11.3 7.5 19.4 24.9 6.7 11.3 11.0 17.0 13.1 13.1 9.3 36.0 30.4 24.8 18.9 21.2 15.3 15.3 11.1 19.7 MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "kidney: 700.9" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 4564.6" "Cancer enriched" "Detected in many" 16 "renal cancer: 56.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 24.9;Hep G2: 5.7;Karpas-707: 12.8;U-266/70: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039451, HPA039562" Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039451: AB_2676513, HPA039562: AB_2676574" "unprognostic (2.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-3)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.85e-2)" "unprognostic (9.83e-2)" "prognostic favorable (2.60e-6)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.23e-2)" 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.8 0.5 0.0 0.2 0.8 0.2 0.0 0.2 0.1 0.0 5.3 0.0 0.2 0.2 700.9 0.4 0.0 0.7 0.2 0.2 0.0 1.2 0.0 0.1 0.1 0.3 0.5 0.0 0.1 0.3 0.1 0.0 0.3 0.2 0.0 0.1 0.2 1.1 0.2 0.2 0.2 14.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.2 0.1 2.0 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.6 0.4 0.0 0.2 0.2 0.0 0.0 24.9 0.0 0.2 0.4 5.7 2.8 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 1.1 0.1 12.8 0.0 1.2 0.0 0.1 0.2 0.5 0.4 0.1 0.1 0.1 2.6 0.1 0.1 0.3 0.0 0.0 0.6 0.5 0.1 1.4 0.0 0.0 0.5 0.1 0.1 7.8 0.7 0.3 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.0 1.7 0.0 13.0 0.8 0.9 0.1 0.0 0.6 0.7 0.8 0.1 1.5 0.0 99.3 0.0 0.0 0.3 0.3 424.6 0.0 0.0 0.1 0.2 0.2 1.2 0.0 0.0 0.9 0.1 0.3 0.0 0.2 0.0 0.1 0.4 0.3 0.1 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 23.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 4564.6 0.0 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.3 7.8 0.0 0.1 0.9 MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.9;salivary gland: 122.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 125.0;Alveolar cells type 2: 389.7;Gastric mucus-secreting cells: 251.8;granulocytes: 187.3;Intestinal goblet cells: 189.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 142.9;MCF7: 255.4;SK-BR-3: 234.5;SK-MEL-30: 182.2;U-87 MG: 236.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" 13.2 1.4 0.6 2.4 0.7 0.1 56.9 0.7 1.6 69.3 1.3 20.4 8.8 18.1 8.9 6.4 18.0 31.0 69.2 1.1 0.7 4.3 39.0 62.7 0.6 1.1 1.0 11.8 16.1 9.0 2.1 1.9 0.8 135.9 21.7 0.3 122.0 13.0 6.6 11.6 15.2 2.8 0.6 0.2 98.1 2.5 0.8 0.9 39.9 2.5 1.2 22.1 21.9 0.9 0.3 133.7 0.3 0.3 58.5 39.5 0.4 26.8 31.5 14.7 18.5 1.1 101.1 0.2 0.1 49.6 51.0 0.3 0.1 0.9 13.0 0.1 0.3 0.1 0.1 0.0 23.3 0.1 0.7 48.1 14.7 43.4 56.2 75.6 0.1 0.0 0.1 0.3 142.9 255.4 0.4 0.6 0.4 105.4 77.1 0.5 0.1 0.2 0.5 3.2 1.5 0.2 0.1 234.5 182.2 0.7 61.5 1.7 26.8 80.1 2.3 0.9 38.0 0.2 0.2 0.2 236.0 0.1 63.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 1.6 1.1 0.7 1.1 1.0 0.8 0.6 0.8 0.9 12.3 125.0 389.7 0.0 0.8 4.1 17.3 6.0 0.0 0.0 95.6 59.7 63.2 52.9 64.2 12.9 0.0 0.4 0.7 34.9 1.9 12.0 0.2 9.5 10.1 10.1 14.4 0.0 0.2 41.3 0.3 4.5 251.8 17.5 187.3 0.2 1.4 28.8 1.2 0.0 0.1 189.0 32.6 0.8 2.9 0.7 8.4 7.4 30.2 5.6 0.6 0.0 0.0 0.0 0.0 58.1 22.4 3.0 0.8 54.4 9.1 0.6 48.5 0.0 0.0 3.1 3.7 0.3 0.6 1.2 2.4 0.7 6.1 0.4 30.5 38.6 MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favorable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 15.5 51.2 17.8 6.3 18.3 5.8 15.8 18.8 26.9 12.4 18.6 15.8 13.0 10.7 21.2 29.1 13.0 6.0 30.0 17.0 18.8 32.8 103.6 14.9 6.2 22.2 19.0 18.9 23.0 9.8 20.5 4.9 21.3 26.5 7.9 7.3 17.1 6.3 21.1 18.2 14.0 5.6 19.0 12.4 17.7 12.6 18.9 5.5 22.1 16.2 6.5 14.1 14.7 22.9 32.2 22.3 22.2 17.6 8.8 17.7 11.3 7.1 16.2 10.3 10.8 25.8 29.5 21.0 19.9 8.0 19.1 32.9 14.6 54.9 4.6 8.2 60.9 8.6 15.9 42.1 31.3 18.4 7.2 24.0 33.5 22.2 9.7 12.3 9.7 16.4 27.5 15.5 7.3 74.7 16.6 29.2 27.3 3.3 31.6 13.6 8.7 53.9 45.3 30.3 34.1 14.8 15.8 29.2 12.7 6.2 60.5 50.5 5.4 8.6 3.6 6.1 10.4 11.9 9.6 24.0 19.0 22.2 23.9 7.4 7.2 1.0 15.3 10.0 12.2 13.6 11.1 12.1 11.3 17.8 15.2 14.6 1.9 11.2 10.9 9.2 5.8 10.3 17.8 18.3 18.8 26.9 17.0 18.8 22.2 19.0 21.3 19.0 18.9 22.9 25.1 35.3 80.8 9.8 20.4 10.3 33.1 105.6 17.1 32.9 59.6 47.0 52.3 60.1 68.9 42.3 29.2 55.4 15.2 33.6 150.6 49.7 41.3 23.8 10.0 22.1 33.0 34.1 6.4 71.3 37.6 24.7 28.5 16.5 16.5 34.3 28.5 225.3 34.8 104.3 8.5 50.4 71.2 20.4 10.2 82.9 40.4 13.5 26.6 4.7 25.1 30.6 30.9 6.6 21.5 29.7 30.0 30.5 18.1 31.8 61.9 143.6 62.1 29.7 13.1 17.9 26.3 26.0 15.8 44.7 19.7 61.8 16.1 121.1 56.6 30.3 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 273.3;Proximal enterocytes: 372.4;Proximal tubular cells: 125.7;Syncytiotrophoblasts: 126.0" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 684.4;BJ hTERT+: 1116.9;HSkMC: 651.1" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 103.9 1.0 0.7 4.5 17.3 11.5 38.5 1.5 1.9 22.7 0.3 1.9 333.5 13.3 22.5 2.3 1.9 13.4 4.3 0.1 0.6 302.5 56.1 27.6 10.3 9.3 2.3 0.9 1.2 0.5 0.6 73.0 10.9 79.6 3.4 0.1 6.1 44.5 20.3 1.9 289.7 1.5 0.9 7.9 1.6 1.3 4.6 16.6 1.2 23.5 12.3 6.0 7.6 0.4 0.1 0.0 0.9 0.3 280.1 684.4 1.6 160.3 1116.9 82.2 209.8 0.0 0.3 172.9 0.1 130.1 107.4 0.5 5.2 6.1 201.3 0.0 0.8 0.0 0.1 0.2 229.6 0.0 0.0 651.1 1.0 40.4 308.1 89.4 59.5 0.4 0.2 0.3 135.1 0.7 0.4 1.0 6.1 0.5 1.1 303.3 139.9 1.6 5.2 1.9 0.5 1.5 0.1 0.5 31.9 68.3 0.2 0.2 165.8 356.4 0.8 115.7 27.9 0.1 0.0 217.3 42.5 0.1 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 139.4 0.0 0.0 1.1 0.0 0.0 0.7 17.3 1.5 1.9 0.1 0.6 9.3 2.3 10.9 0.9 4.6 0.4 5.9 9.6 13.0 0.3 2.3 0.8 74.1 2.5 0.0 0.0 1.5 64.1 1.6 21.5 11.2 22.0 0.0 82.1 6.9 0.0 9.8 0.2 0.5 6.2 273.3 6.6 0.0 0.0 2.2 0.0 57.8 40.6 0.0 5.7 2.5 0.0 2.9 53.2 8.9 0.0 8.1 9.9 2.0 3.1 1.2 0.5 4.1 10.7 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.6 13.8 1.2 0.1 40.0 372.4 125.7 1.6 0.0 0.0 17.4 11.1 0.2 0.5 0.1 0.3 126.0 2.5 0.1 12.6 33.6 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "urinary bladder: 12.9" "Cell type enriched" "Detected in some" 12 "Basal respiratory cells: 426.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 17.9;PC-3: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 12.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 17.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 426.0 0.0 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.8 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Excitatory neurons: 24.6;Horizontal cells: 15.2;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.0;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.3;CACO-2: 56.0;EFO-21: 15.8;RPTEC TERT1: 24.6;U-2 OS: 17.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 3.4 1.0 6.1 0.5 5.8 0.7 0.5 40.0 8.1 0.7 3.5 0.7 2.1 1.3 0.1 0.3 2.2 0.6 0.6 6.0 5.6 7.8 0.5 4.7 0.4 4.4 5.6 0.4 5.8 0.3 3.8 0.2 5.4 1.7 0.2 2.5 0.5 4.2 0.3 1.2 1.4 2.0 2.7 0.4 0.6 0.4 7.2 0.0 0.7 0.1 0.0 0.4 0.3 4.8 0.6 36.3 0.1 0.2 0.2 0.0 1.0 1.9 2.3 3.8 2.0 56.0 9.7 0.0 15.8 2.5 1.2 0.6 8.5 0.0 1.6 0.2 0.3 1.9 1.2 0.6 0.0 0.1 0.4 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.1 0.5 0.4 0.5 0.1 0.2 13.6 0.1 2.4 0.1 0.2 0.0 24.6 0.1 14.1 9.7 2.5 0.7 0.3 2.9 0.5 0.3 0.6 7.4 17.7 1.8 0.7 0.3 0.2 0.1 1.6 0.2 1.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 6.1 5.8 40.0 8.1 6.0 5.6 4.4 5.6 5.4 2.7 7.2 4.8 0.3 16.0 1.5 5.2 0.0 0.1 0.2 0.0 0.0 3.9 0.2 0.8 0.5 8.6 1.3 1.8 0.0 0.1 0.1 0.7 5.9 8.5 0.6 0.8 0.3 1.4 0.0 0.0 24.6 0.9 0.1 0.6 0.0 0.5 0.0 0.1 0.4 0.4 0.0 15.2 38.4 0.1 0.0 0.6 0.0 0.0 0.3 0.1 1.8 10.3 0.0 0.2 0.0 12.5 12.0 1.9 0.1 0.0 0.0 0.4 2.3 11.4 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.1 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 219.1;Kupffer cells: 408.5;Langerhans cells: 241.7;Macrophages: 412.0;monocytes: 1118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Group enriched" "Detected in some" 14 "NB-4: 151.8;THP-1: 282.7;U-937: 185.5" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" 24.2 14.9 2.7 82.4 2.8 292.9 6.0 2.9 4.4 6.3 3.2 6.7 3.7 4.0 1.4 7.4 5.7 26.6 4.3 2.6 3.1 3.6 11.5 47.3 15.6 5.2 4.3 2.2 4.8 3.7 1.6 20.4 4.3 3.8 7.7 12.1 5.7 3.5 3.8 5.1 7.7 20.7 5.1 107.8 4.5 5.1 4.2 14.4 3.8 19.0 14.5 23.4 1.8 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 282.7 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 185.5 0.0 155.4 1354.4 243.8 2.6 534.3 3.7 33.5 1.6 1.9 616.5 15.3 1.6 1.4 6012.8 2.8 270.6 9.6 1.5 1099.5 2.7 2.8 2.9 4.4 2.6 3.1 5.2 4.3 4.3 5.1 4.2 5.4 2.6 35.3 56.0 0.0 34.7 2.4 0.0 0.0 0.0 1.2 1.1 3.4 0.9 5.7 9.3 0.0 0.0 0.9 5.9 0.0 0.0 0.0 0.4 0.1 0.1 5.0 0.0 22.3 0.0 0.4 1.3 6.5 0.5 0.1 44.1 0.0 3.9 2.2 219.1 0.0 0.1 0.0 0.0 408.5 241.7 3.3 1.2 412.0 1.8 33.7 1118.9 136.1 26.8 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 1.7 8.0 4.8 13.1 1.5 8.2 0.9 0.3 0.4 2.3 1.0 11.7 0.0 0.0 0.1 MOB2 HCCA2 ENSG00000182208 "MOB kinase activator 2" Q70IA6 11 1469457-1501247 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046313 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Nucleoplasm, Cytosol" "HPA046313: AB_10959882" "unprognostic (5.02e-1)" "unprognostic (5.71e-2)" "unprognostic (6.24e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.30e-2)" "unprognostic (1.06e-3)" "unprognostic (3.06e-2)" "unprognostic (1.77e-1)" "unprognostic (2.80e-2)" "unprognostic (5.30e-2)" "unprognostic (2.87e-1)" "prognostic favorable (2.02e-4)" "unprognostic (2.67e-1)" "unprognostic (8.56e-2)" "unprognostic (9.78e-2)" "unprognostic (1.15e-1)" 32.3 19.6 34.7 19.2 36.3 24.2 28.3 37.8 39.7 27.4 36.2 61.1 18.0 30.7 36.5 51.9 34.4 27.8 43.5 35.3 36.5 18.6 20.0 24.7 26.8 36.1 36.8 28.1 32.8 34.9 11.2 25.7 36.5 32.5 34.8 14.6 35.2 42.3 50.9 50.0 28.6 49.0 36.1 25.1 27.9 14.2 37.1 34.1 24.2 70.4 27.0 39.9 31.6 37.8 29.3 31.2 18.3 15.7 44.2 30.8 17.1 22.5 30.9 40.4 31.8 20.1 39.0 20.9 16.7 50.6 26.0 34.8 28.1 48.6 24.3 28.8 44.3 16.0 11.7 26.2 30.2 21.2 24.2 25.1 57.9 21.9 25.3 32.7 43.6 27.0 26.3 21.2 20.7 20.6 27.4 37.7 23.0 54.3 29.4 19.9 19.0 22.2 34.4 26.9 34.6 37.3 27.3 34.0 27.9 23.0 15.9 21.3 37.7 25.6 13.1 8.3 14.5 21.6 22.3 21.8 17.9 20.3 19.8 9.7 8.7 11.9 16.2 9.2 13.6 8.1 14.1 13.7 10.6 11.0 11.6 10.2 7.1 12.1 13.4 7.5 15.3 10.6 34.7 36.3 37.8 39.7 35.3 36.5 36.1 36.8 36.5 36.1 37.1 37.8 84.8 6.4 10.0 6.5 20.2 82.2 30.1 39.4 12.0 18.4 27.8 33.3 14.8 12.8 18.4 7.3 12.5 31.1 64.5 58.6 27.4 33.5 24.3 18.9 17.7 58.2 20.9 36.2 15.2 38.5 31.0 23.3 16.8 29.2 24.8 20.3 33.9 9.0 26.4 43.7 10.9 32.8 32.6 18.2 39.3 12.1 23.9 28.1 56.9 11.2 29.4 21.5 81.4 6.6 14.8 39.6 63.2 51.1 17.0 48.6 54.3 23.9 12.9 21.4 85.5 20.8 68.3 29.8 41.1 13.7 82.0 59.4 36.4 20.2 27.7 37.6 MOB3B "C9orf35, FLJ13204, MOB1D, MOBKL2B" ENSG00000120162 "MOB kinase activator 3B" Q86TA1 9 27325209-27529814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 431.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5;myeloid DC: 2.7;naive B-cell: 2.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 16.0;HAP1: 16.7;K-562: 49.9;SK-BR-3: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (6.96e-3)" "unprognostic (9.60e-2)" "unprognostic (5.10e-3)" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (1.02e-1)" "unprognostic (1.87e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (7.57e-3)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "prognostic favorable (2.33e-10)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.99e-2)" 5.7 1.7 10.0 3.9 23.8 0.7 6.2 19.3 14.4 7.1 11.7 12.1 17.5 9.6 5.1 3.6 7.9 4.9 1.4 8.5 13.5 7.4 1.4 6.7 4.0 23.7 19.4 26.0 3.6 0.5 1.1 4.6 22.8 2.2 13.1 7.4 3.4 2.9 5.9 6.3 15.6 6.3 19.2 8.1 5.6 3.2 19.2 3.6 5.4 5.3 5.6 3.6 4.7 30.4 3.4 2.5 7.6 0.0 1.9 0.1 16.0 0.0 0.1 0.1 0.1 1.9 0.0 0.1 3.2 0.0 0.0 10.9 16.7 13.2 0.0 7.7 2.6 4.9 9.8 0.1 0.0 0.0 1.0 3.4 13.7 0.0 2.5 0.0 0.0 0.0 49.9 0.1 0.0 0.0 0.0 0.0 9.8 6.3 0.9 3.3 0.7 0.1 4.6 6.4 0.1 2.4 2.7 19.8 4.7 9.9 1.3 0.0 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.5 0.0 0.5 0.0 0.0 0.8 0.0 2.5 0.0 0.0 2.7 2.9 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.3 10.0 23.8 19.3 14.4 8.5 13.5 23.7 19.4 22.8 19.2 19.2 30.4 6.9 3.2 4.1 13.7 22.1 22.7 7.7 7.6 40.9 2.1 6.7 12.6 1.5 27.1 4.3 11.0 0.0 22.1 0.4 83.3 9.8 16.4 1.0 6.5 20.1 8.7 2.4 1.7 81.7 21.0 56.0 20.8 21.4 9.2 1.3 1.9 4.6 3.1 5.4 1.7 88.9 26.9 12.2 13.2 30.6 3.1 15.8 20.4 16.0 76.8 10.8 65.3 2.1 79.4 431.9 10.6 26.1 16.1 1.2 6.5 50.3 10.5 2.7 1.3 0.0 4.5 19.2 2.2 5.0 8.4 9.5 11.8 1.6 7.7 36.8 6.9 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 48.2;liver: 25.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.8;Hepatocytes: 79.6;Intestinal goblet cells: 36.2;Proximal enterocytes: 159.6;Undifferentiated cells: 32.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 4.5;RPMI-8226: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028834 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.0 0.0 0.0 1.9 0.2 0.0 1.4 0.0 0.1 0.1 0.0 13.9 44.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 12.6 0.0 0.2 0.2 0.0 0.6 48.2 0.7 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.3 1.5 0.2 0.0 0.0 0.0 0.0 73.8 0.0 0.0 0.0 0.1 0.0 0.0 2.4 2.7 0.0 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.4 79.6 0.0 0.0 0.0 36.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 21.3 0.0 0.0 0.6 159.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.4 0.1 MON1B "HSRG1, KIAA0872, SAND2" ENSG00000103111 "MON1 homolog B, secretory trafficking associated" Q7L1V2 16 77190835-77202398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046285 Approved Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA046285: AB_10959467" "unprognostic (1.73e-2)" "unprognostic (9.99e-2)" "unprognostic (9.97e-2)" "prognostic favorable (6.90e-4)" "unprognostic (1.94e-1)" "unprognostic (7.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-2)" "unprognostic (9.78e-2)" "unprognostic (2.42e-2)" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "prognostic favorable (9.42e-5)" "unprognostic (2.21e-2)" "unprognostic (3.62e-2)" "unprognostic (8.34e-3)" "unprognostic (1.75e-1)" 12.9 9.6 19.3 17.2 25.5 15.7 9.0 20.8 18.9 11.1 9.4 15.6 16.3 10.6 12.0 13.2 10.8 13.2 10.5 18.1 19.1 10.6 12.4 12.6 18.3 24.9 24.0 8.8 13.7 17.5 8.3 8.1 21.2 19.7 13.1 21.0 13.9 10.2 11.4 13.6 16.0 9.7 20.6 15.2 13.7 5.6 22.6 15.3 19.7 7.7 15.5 11.8 7.1 23.0 14.8 35.7 15.0 15.5 16.0 15.9 20.5 14.6 17.4 13.0 13.9 20.9 22.4 26.9 24.1 11.9 23.3 29.8 15.7 14.5 11.5 19.6 17.9 19.0 12.7 20.5 22.4 20.9 52.5 15.7 28.5 19.3 17.2 14.0 24.5 24.7 25.6 9.0 11.3 29.9 26.3 24.6 15.5 19.9 9.6 34.0 10.3 30.4 14.9 11.9 22.4 18.8 25.5 10.2 17.6 10.7 23.3 30.6 26.2 16.2 18.5 18.4 13.0 30.0 21.4 72.9 28.7 21.4 20.3 17.8 9.7 16.6 9.5 16.3 9.8 6.0 7.6 8.8 8.3 7.0 5.6 7.2 21.7 10.3 11.1 4.7 9.9 9.0 19.3 25.5 20.8 18.9 18.1 19.1 24.9 24.0 21.2 20.6 22.6 23.0 19.4 38.5 34.8 1.6 17.3 7.5 10.0 12.7 8.0 15.0 16.6 14.4 12.6 12.8 19.8 14.7 18.8 10.5 16.9 42.3 3.9 14.0 17.8 13.1 15.6 20.7 24.0 16.2 1.9 19.5 12.4 12.6 21.9 20.0 12.7 17.4 19.6 28.4 13.2 8.4 3.0 27.9 10.2 32.0 7.8 14.1 9.0 18.7 8.8 4.7 26.1 21.5 26.8 3.0 5.0 20.0 18.7 10.1 13.8 21.0 23.8 11.7 14.6 23.5 19.7 21.6 11.0 10.4 5.3 14.6 9.5 16.8 17.2 10.9 23.5 18.8 MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916675-167937072 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2288.1;Late spermatids: 5134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA056091: AB_2683035" "unprognostic (3.25e-1)" "unprognostic (6.82e-2)" "unprognostic (8.79e-3)" "unprognostic (4.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-3)" "unprognostic (1.44e-3)" "unprognostic (1.08e-2)" "unprognostic (9.13e-2)" "unprognostic (2.39e-1)" "unprognostic (6.95e-2)" "unprognostic (5.43e-2)" "unprognostic (1.67e-1)" 53.6 89.9 32.3 15.8 37.1 63.3 50.7 34.2 39.0 34.3 35.0 80.3 47.8 30.6 15.8 38.8 34.5 19.6 174.0 36.8 35.6 148.1 266.6 35.1 14.0 31.8 33.4 35.3 52.4 35.6 73.5 13.8 31.6 89.3 33.7 28.4 55.3 16.0 162.1 42.5 65.8 14.8 31.5 28.9 140.4 240.4 34.9 20.1 32.3 66.3 15.0 43.0 35.4 34.4 40.7 43.2 14.6 32.3 31.5 26.2 4.1 70.2 26.9 23.7 27.2 92.3 19.6 75.0 49.4 29.1 21.4 31.4 17.0 28.1 20.3 98.3 34.5 33.2 34.1 60.7 22.4 38.1 21.9 19.6 23.6 41.8 21.8 20.0 20.3 52.5 39.6 34.9 38.7 18.1 52.4 31.4 26.2 73.7 45.2 27.8 31.3 54.7 155.0 30.5 25.8 28.4 41.6 39.1 34.3 29.2 73.9 38.9 30.4 27.8 24.8 45.3 29.9 61.2 65.9 74.5 73.5 28.6 14.6 95.0 33.1 92.5 44.1 30.5 45.7 50.2 51.6 45.8 58.7 41.3 48.6 46.7 61.4 55.6 38.5 40.2 81.3 84.2 32.3 37.1 34.2 39.0 36.8 35.6 31.8 33.4 31.6 31.5 34.9 34.4 81.6 35.3 43.7 14.4 75.0 126.1 157.7 213.8 52.9 54.5 167.2 166.9 428.0 513.3 119.2 130.6 22.9 468.6 78.2 267.5 1025.2 206.1 2288.1 153.3 38.5 75.0 331.5 388.3 23.5 145.5 55.3 119.3 112.1 98.3 88.2 332.1 55.3 679.5 159.6 45.4 19.9 326.4 146.5 77.1 113.3 5134.8 106.2 93.9 120.9 15.9 272.9 123.8 76.2 13.0 16.8 100.5 237.2 112.8 84.7 245.6 516.2 974.3 175.3 69.7 65.7 90.3 147.1 788.0 170.5 75.3 114.4 343.1 94.9 705.0 415.5 173.9 MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Excitatory neurons: 213.6;Inhibitory neurons: 271.3;Oligodendrocyte precursor cells: 158.8;Oligodendrocytes: 279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.1;HUVEC TERT2: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" 22.7 9.9 18.0 5.3 23.2 0.2 13.2 20.3 20.6 14.3 21.7 16.1 2.8 17.8 15.3 7.6 17.5 11.7 29.8 18.0 20.4 18.8 85.7 11.1 3.9 19.8 22.4 25.6 4.6 11.3 10.7 24.7 20.3 19.2 5.3 33.0 6.3 23.2 19.9 3.8 6.4 18.6 21.4 11.1 7.6 11.5 17.7 4.3 11.7 31.3 1.8 12.6 9.9 35.3 16.1 21.2 58.1 26.0 39.2 35.4 11.8 15.9 16.4 13.8 13.1 0.0 0.0 0.0 4.5 39.6 14.2 0.3 17.3 8.8 22.3 0.0 10.2 10.5 21.9 3.9 20.8 0.1 5.4 26.5 3.6 9.7 6.6 35.3 53.5 0.0 0.3 0.1 12.5 4.2 0.0 0.2 24.9 0.0 9.0 0.0 14.2 0.0 13.7 8.5 7.2 26.9 12.6 2.8 15.5 39.7 8.1 0.1 42.8 14.1 2.7 4.7 12.4 0.0 0.0 0.0 6.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 23.2 20.3 20.6 18.0 20.4 19.8 22.4 20.3 21.4 17.7 35.3 70.9 32.1 7.9 121.5 0.2 5.1 10.1 4.8 3.4 30.9 8.6 15.6 109.7 1.5 14.7 7.3 39.6 16.1 0.4 0.1 1.9 4.2 4.2 27.0 12.4 44.6 1.8 2.1 213.6 2.0 22.9 27.4 1.5 6.3 1.3 39.5 42.5 74.4 5.8 26.9 271.3 0.2 6.1 0.6 6.8 3.7 24.2 0.9 17.8 60.9 0.6 40.2 0.0 158.8 279.6 1.8 0.0 33.8 0.1 12.9 0.0 16.4 36.6 25.4 39.5 35.1 40.8 6.7 13.9 0.1 4.0 10.8 0.8 7.6 0.0 4.7 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSLNL "C16orf37, MPFL" ENSG00000162006 "Mesothelin like" Q96KJ4 16 769428-783370 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CAPAN-2: 11.2;HeLa: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (5.26e-4)" "unprognostic (3.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.38e-2)" "unprognostic (1.54e-1)" "unprognostic (3.73e-3)" "unprognostic (6.50e-2)" "unprognostic (2.09e-1)" "unprognostic (5.36e-2)" "unprognostic (2.16e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9384.0" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 10715.4" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 25.6;NB-4: 21.6;RPMI-8226: 11.3;SH-SY5Y: 6.1;SK-BR-3: 5.9;U-2197: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" NA NA 6000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" 5.1 4.5 0.0 3.0 0.0 0.1 20.5 0.0 0.0 3.2 0.0 2.8 10.3 0.3 45.1 12.3 4.6 3.0 0.5 0.0 0.0 1.8 1.8 29.9 0.2 0.0 0.0 0.3 2.3 0.2 0.5 0.6 0.0 9384.0 0.1 0.0 31.9 0.6 0.4 39.7 2.3 0.0 0.0 0.7 552.3 10.1 0.0 1.0 0.7 0.0 10.0 7.2 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 25.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 21.6 0.2 0.0 0.0 0.0 0.0 11.3 0.0 1.6 1.0 6.1 0.0 5.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.3 0.0 195.9 586.4 0.0 0.0 6.4 1.3 0.0 4.3 2203.2 0.0 0.0 2.1 0.1 0.3 0.0 0.1 48.9 0.6 0.0 10.7 0.0 0.0 0.1 0.2 0.4 9.5 404.2 0.2 1.3 0.0 0.0 1.2 0.2 0.0 0.0 0.8 419.1 0.0 0.0 78.8 0.3 30.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.8 29.6 0.0 0.8 10715.4 0.3 0.0 570.6 0.0 0.0 0.0 271.0 0.5 1.4 0.0 0.4 1.5 14.3 0.0 0.1 192.4 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943293 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 275.6;monocytes: 178.7;Proximal tubular cells: 496.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1414.9;neutrophil: 3051.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 3051.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153" "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" 28.1 15.1 26.2 31.8 27.3 96.3 21.3 27.8 28.4 17.5 25.8 36.7 29.4 29.5 11.2 45.3 33.5 23.2 47.3 25.6 26.8 80.3 234.2 30.4 17.7 29.3 28.0 16.4 149.6 14.8 14.5 13.2 27.1 32.0 17.4 2.7 16.5 29.2 76.0 31.1 27.5 36.8 27.5 67.0 33.3 17.7 28.5 13.7 12.5 93.6 12.2 40.8 20.1 27.1 23.6 59.1 21.3 50.4 39.9 17.0 36.4 27.8 36.0 41.2 35.6 96.2 25.5 22.7 90.6 33.5 36.0 37.9 36.3 25.2 12.8 127.7 41.1 17.5 20.5 154.9 36.1 49.3 40.3 32.0 21.9 29.6 6.0 12.9 41.9 28.8 28.2 12.3 22.3 131.2 28.2 82.7 29.2 42.7 33.5 40.3 29.3 106.0 66.0 37.2 20.5 26.9 32.3 35.6 17.3 13.9 38.7 87.9 24.8 12.3 33.7 24.3 16.7 32.0 53.4 42.4 12.5 47.4 22.0 493.5 412.0 1414.9 31.9 194.8 32.2 28.0 26.5 26.7 171.2 28.3 20.5 22.7 3051.8 42.2 182.9 73.2 45.9 226.7 26.2 27.3 27.8 28.4 25.6 26.8 29.3 28.0 27.1 27.5 28.5 27.1 24.9 9.6 13.4 3.9 10.0 6.5 9.1 21.5 8.0 6.5 27.9 21.3 36.1 32.9 14.9 33.1 4.2 33.3 12.3 69.1 93.9 65.9 5.9 23.9 13.4 15.4 60.3 21.5 0.8 111.2 121.4 13.7 11.7 17.0 4.5 12.2 20.7 275.6 63.5 8.4 1.2 38.6 34.6 59.2 21.2 13.9 9.3 37.9 16.0 2.8 178.7 22.5 25.7 1.5 2.9 66.0 62.8 23.0 13.0 16.3 97.3 496.8 37.9 4.2 0.0 8.1 22.8 28.9 8.7 11.1 9.5 38.6 10.6 14.8 33.5 21.9 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1949.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Respiratory ciliated cells: 168.3;Syncytiotrophoblasts: 665.9" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enriched" "Detected in single" 7 "basal ganglia: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;K-562: 11.7;SK-BR-3: 18.0;SuSa: 12.0;U-266/70: 7.8;U-266/84: 21.1" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in many" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" 0.1 0.3 0.4 0.0 4.5 0.0 15.4 0.0 0.6 6.5 1.1 0.0 0.0 0.4 1949.7 17.4 6.7 0.1 0.0 0.3 0.0 24.1 0.1 12.3 0.1 0.0 0.0 0.0 7.8 0.0 1.4 14.8 0.1 0.9 0.0 0.0 52.2 6.8 0.0 29.4 0.0 0.0 0.0 0.0 1.0 0.2 0.0 3.6 75.7 0.0 7.7 2.5 11.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.6 0.0 18.0 0.0 12.0 0.2 0.0 0.0 0.0 3.1 0.0 0.0 7.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 109.0 32.5 0.0 0.1 3.4 12.5 7.5 4.6 0.0 43.0 6.9 0.0 0.0 55.1 49.7 0.0 68.7 0.0 0.0 31.3 4.6 0.6 39.8 5.4 0.7 0.0 0.0 0.2 0.0 19.2 1.3 0.0 53.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 8.2 0.0 0.6 0.2 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 168.3 0.0 0.0 0.0 2.2 0.2 0.2 26.5 29.7 665.9 0.4 0.0 0.0 12.6 MUC16 "CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.2;cervix: 15.9;fallopian tube: 5.9;salivary gland: 6.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 40.3;Club cells: 81.8;Endometrial ciliated cells: 74.3;Glandular and luminal cells: 157.8;Ionocytes: 99.7;Respiratory ciliated cells: 197.4" "Cancer enriched" "Detected in many" 4 "ovarian cancer: 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 23.3;HeLa: 45.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB055172, HPA065600" Enhanced "Secreted in other tissues" NA NA 25000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB055172: AB_2148831, HPA065600: AB_2732736" "unprognostic (8.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.37e-2)" "unprognostic (3.07e-1)" "unprognostic (1.76e-2)" "unprognostic (3.01e-3)" "unprognostic (3.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (2.60e-8)" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "unprognostic (3.68e-3)" 7.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.9 0.0 0.0 0.0 2.1 0.0 0.3 5.9 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 6.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.6 2.8 0.0 0.0 7.7 0.0 0.0 0.0 0.1 0.0 0.0 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.5 0.3 0.1 40.3 0.0 0.0 4.1 0.9 3.4 1.5 81.8 0.0 0.0 2.1 0.2 0.0 0.0 0.2 14.3 74.3 14.8 1.2 0.0 0.0 0.4 0.0 0.4 1.0 0.0 157.8 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 99.7 0.3 0.0 16.4 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 197.4 0.0 0.0 0.0 8.6 0.3 0.2 0.0 0.3 3.3 0.6 0.0 0.0 0.7 MUC4 ENSG00000145113 "Mucin 4, cell surface associated" Q99102 3 195746765-195811973 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 19.2;intestine: 31.1;prostate: 14.8;vagina: 15.0" "Cell type enhanced" "Detected in many" "Club cells: 193.7;Distal enterocytes: 185.1;Gastric mucus-secreting cells: 163.1;Intestinal goblet cells: 193.3;Respiratory ciliated cells: 336.1;Undifferentiated cells: 174.5;Urothelial cells: 319.4" "Cancer enhanced" "Detected in many" "cervical cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "basal ganglia: 3.4" "HPA005895, CAB013536" Approved "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB013536: , HPA005895: AB_1079427" "unprognostic (4.16e-3)" "unprognostic (1.00e-2)" "unprognostic (6.79e-2)" "unprognostic (1.11e-2)" "unprognostic (3.03e-2)" "unprognostic (5.16e-2)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (3.19e-1)" "unprognostic (4.22e-3)" "unprognostic (6.68e-3)" "unprognostic (5.30e-2)" "unprognostic (2.43e-3)" "unprognostic (3.19e-1)" "unprognostic (6.78e-2)" "unprognostic (3.46e-3)" "unprognostic (9.97e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.1 5.4 0.0 31.1 0.0 0.0 0.0 19.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.8 0.0 7.8 0.0 0.0 0.0 3.4 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.2 1.2 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 6.4 15.6 0.3 2.1 0.0 18.5 82.1 0.6 0.0 25.7 2.9 2.5 0.0 193.7 0.0 0.0 0.1 0.3 185.1 0.0 1.6 3.5 6.2 0.2 0.7 16.4 0.0 0.9 5.2 4.3 0.6 163.1 5.1 2.5 0.1 0.0 0.0 0.1 0.0 1.0 193.3 40.7 0.0 0.0 0.7 0.0 1.8 0.0 1.0 0.0 0.0 0.0 0.0 0.2 37.5 64.3 0.4 0.8 12.4 1.1 0.2 336.1 0.0 0.0 0.5 11.1 2.1 1.9 0.4 0.0 0.1 1.2 2.3 174.5 319.4 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711016 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 203.7;Muller glia cells: 365.7;Rod photoreceptor cells: 163.8;Theca cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 663.8" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA044819: AB_10964134, HPA075316: " "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (3.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (8.33e-2)" "unprognostic (5.39e-3)" "unprognostic (4.67e-3)" "unprognostic (6.21e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.80e-5)" 189.2 244.3 111.9 53.4 175.1 13.5 133.5 114.5 136.5 149.4 263.7 310.7 37.5 268.3 208.8 157.0 181.0 103.6 526.4 123.4 118.4 83.0 29.9 124.9 31.8 130.3 122.7 185.4 90.3 235.7 48.8 102.8 125.3 154.3 76.1 514.6 62.0 314.8 68.8 73.0 89.4 284.4 122.1 149.7 124.0 115.7 115.4 44.6 272.1 75.9 33.3 250.5 123.1 120.4 19.1 56.1 82.4 155.3 424.0 384.4 41.0 263.8 212.8 188.8 182.8 75.1 2.9 0.5 116.8 368.0 196.8 75.7 92.5 146.5 306.4 1.4 91.7 48.7 39.2 126.8 258.4 22.9 5.9 241.1 171.2 219.3 178.7 421.8 282.0 12.3 35.2 1.2 440.8 5.3 2.9 15.9 26.5 30.0 156.7 43.2 322.2 16.5 153.1 4.8 28.8 207.3 78.5 1.0 152.6 231.6 51.5 29.3 348.5 422.7 90.1 174.3 282.6 24.5 4.9 1.4 663.8 9.9 62.5 1.3 2.8 0.5 4.0 0.8 3.1 2.3 2.1 4.5 2.1 0.4 1.3 2.9 1.1 5.4 0.3 2.4 0.5 3.4 111.9 175.1 114.5 136.5 123.4 118.4 130.3 122.7 125.3 122.1 115.4 120.4 128.3 16.0 14.6 8.5 2.0 10.3 27.0 15.0 13.6 142.0 9.4 42.5 117.3 2.8 10.3 31.3 95.9 1.4 62.6 1.3 1.9 25.5 3.5 48.7 203.7 56.1 6.7 0.8 19.3 4.1 8.1 97.2 2.0 63.9 2.5 64.7 52.5 4.2 3.5 111.0 27.9 7.5 10.2 5.0 13.3 12.4 101.2 7.4 14.2 10.3 1.3 365.7 6.2 15.1 8.9 6.5 0.3 143.3 11.0 21.2 1.6 8.1 10.2 163.8 13.1 132.1 83.6 2.3 10.7 6.0 8.8 0.8 19.7 218.5 1.5 21.1 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69367726 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;breast: 5.3;esophagus: 9.6;stomach 1: 6.0" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 199.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 172.8;A549: 83.5;CAPAN-2: 24.3;U-2 OS: 36.1" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" 5.4 0.1 0.0 0.6 0.0 0.1 5.3 0.0 0.0 1.8 0.0 0.5 0.3 0.0 0.7 9.6 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 4.1 0.2 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 3.9 0.0 172.8 83.5 0.0 0.0 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.5 24.3 0.5 6.3 0.0 0.1 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.1 8.5 0.0 2.4 0.2 0.1 3.8 0.1 0.1 0.2 3.4 6.8 0.0 0.1 3.5 0.6 0.2 0.0 0.0 0.0 2.4 0.6 0.0 2.9 0.7 1.6 0.1 36.1 0.0 1.4 0.3 1.7 0.2 0.2 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.0 0.8 0.8 3.8 0.0 0.0 30.7 37.7 0.4 0.0 17.6 3.7 0.0 0.0 0.9 7.8 0.0 12.6 12.7 1.2 0.1 0.5 0.0 0.0 0.0 9.4 0.4 3.4 23.9 1.5 0.0 0.1 0.0 0.2 2.4 0.0 0.0 1.3 2.0 0.0 0.0 6.9 0.3 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 199.3 22.3 0.0 3.9 1.4 0.0 0.0 1.5 0.0 0.0 0.1 2.9 0.0 0.4 3.4 1.3 0.1 0.4 0.0 2.7 8.5 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYL6 "ESMLC, MLC1SM, MLC3NM" ENSG00000092841 "Myosin light chain 6" P60660 12 56158346-56163496 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046859, HPA063034" Approved NA NA 60000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.89e-1)" "unprognostic (3.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" "unprognostic (2.04e-1)" "unprognostic (2.86e-2)" "unprognostic (8.33e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (2.01e-1)" 2247.0 1427.5 830.7 1207.0 830.7 1756.5 1977.9 864.2 962.6 1767.3 901.0 5900.2 1027.9 2971.8 1635.0 1777.8 2197.9 905.8 1153.9 809.9 863.8 1915.8 1172.0 1946.7 882.9 900.5 874.9 1155.2 1032.8 1466.7 747.7 1441.7 869.2 2037.5 2360.3 927.1 1167.6 2912.2 411.1 1090.1 1867.5 4209.9 858.5 1547.8 2128.0 494.6 899.3 1151.3 1316.7 578.7 1404.7 3041.7 1685.0 869.9 1924.9 1739.1 3199.3 958.8 2063.5 2065.5 1755.8 4056.4 4162.8 5469.7 3191.3 2738.5 1720.0 735.0 2274.3 5778.4 1417.7 1222.8 1995.9 2846.0 3556.8 1423.1 666.5 1311.5 2481.7 1536.9 1512.2 913.8 2304.1 2389.9 2013.5 3242.3 1263.1 4706.8 4854.4 867.2 708.1 2121.5 4585.6 2052.1 1291.6 1402.8 1629.5 1071.6 1746.1 1027.3 1265.3 932.9 5125.1 2361.7 1169.2 862.9 4456.0 1380.0 760.4 2312.4 2148.7 2383.0 5212.3 1486.3 1011.6 2077.3 2746.8 635.3 1150.3 867.7 1953.3 1168.9 1578.1 11449.4 4509.8 13302.4 3191.2 5016.0 2404.9 2844.7 2828.6 2994.0 4747.3 2558.5 2020.7 2528.3 8440.7 2233.9 6531.2 5167.0 4209.8 14776.8 830.7 830.7 864.2 962.6 809.9 863.8 900.5 874.9 869.2 858.5 899.3 869.9 2044.5 1733.9 1161.8 16.0 704.4 2114.0 2470.4 2988.3 746.1 278.4 896.3 1394.8 672.8 946.5 2016.5 1475.0 316.9 1704.4 1144.5 2568.2 2406.5 4126.7 292.4 1134.2 1714.2 1628.1 1017.3 857.4 15.6 4820.4 2604.5 1264.0 871.6 1676.6 994.3 1307.8 1328.6 887.8 3370.3 80.8 19.8 1572.3 1845.3 1148.3 2472.8 910.7 1064.0 1872.2 1469.2 39.4 4426.3 820.8 1195.7 17.6 31.3 6222.1 2715.8 2775.1 892.8 1762.1 3007.9 2956.9 1870.9 763.7 1735.5 685.8 3305.2 76.2 115.0 1139.6 2066.1 1929.9 1191.9 1039.1 1406.1 2558.6 MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 8015.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 860.2;Cardiomyocytes: 1856.1;Peritubular cells: 1891.9;Sertoli cells: 2143.1;Smooth muscle cells: 2525.7;Theca cells: 881.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 783.3;BJ: 1047.3;fHDF/TERT166: 844.3;hTERT-RPE1: 645.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 76.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" 944.6 948.6 61.6 347.0 76.7 5.2 649.5 63.3 132.2 1083.0 104.6 8015.9 270.5 2897.3 238.2 999.8 1643.3 364.3 2294.5 61.4 63.1 352.2 116.6 617.9 56.4 66.3 66.3 717.2 82.0 45.4 91.2 160.3 66.1 2347.4 345.8 22.8 200.7 2248.7 164.3 289.2 1287.7 2107.8 62.0 274.3 1946.4 260.7 66.5 27.4 431.7 111.4 23.2 4176.1 943.6 63.3 79.4 1.3 60.3 1.2 783.3 298.6 264.5 1047.3 450.9 541.3 349.9 612.3 9.1 0.2 535.6 844.3 120.6 29.4 0.2 2.4 125.7 0.9 0.2 16.7 114.4 57.3 500.4 0.4 17.7 420.8 54.4 359.9 1.6 645.9 19.2 0.0 2.4 28.0 461.7 0.2 0.3 7.8 24.0 16.1 5.6 0.4 0.0 5.8 4.6 5.8 0.6 4.1 11.1 26.6 0.6 257.5 232.9 15.6 137.0 510.9 220.1 75.5 1.0 0.8 4.0 2.3 194.3 0.8 0.6 0.0 0.1 2.2 0.0 0.0 0.0 0.9 0.0 0.1 0.3 0.2 0.0 0.0 1.9 0.2 0.0 0.4 0.0 7.2 61.6 76.7 63.3 132.2 61.4 63.1 66.3 66.3 66.1 62.0 66.5 63.3 325.3 394.2 52.3 0.0 6.6 60.7 320.2 167.1 21.6 1.4 36.8 860.2 1856.1 24.3 50.8 90.1 0.0 37.0 6.3 0.1 27.4 310.3 9.3 13.1 419.9 179.7 0.0 5.7 0.2 116.0 78.3 410.4 10.2 9.3 15.2 234.3 169.9 2.7 32.0 1.7 0.1 1.2 14.2 5.0 76.6 55.4 331.8 111.7 72.9 30.9 19.4 230.4 6.2 0.0 0.5 47.9 2.5 1891.9 6.4 156.9 105.5 42.1 31.8 6.1 2143.1 65.9 2525.7 16.3 9.5 6.5 53.4 26.8 14.7 881.1 2.0 61.9 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYOM1 ENSG00000101605 "Myomesin 1" P52179 18 3066807-3219968 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "heart muscle: 412.8;skeletal muscle: 845.6;tongue: 435.6" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 1346.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HAP1: 13.5;HMC-1: 3.5;HSkMC: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014305, HPA049193" Enhanced NA NA 33000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA014305: AB_1854257, HPA049193: AB_2680670" "unprognostic (2.51e-1)" "unprognostic (2.08e-3)" "unprognostic (2.19e-3)" "unprognostic (8.01e-3)" "unprognostic (8.94e-2)" "unprognostic (4.31e-2)" "unprognostic (9.10e-2)" "unprognostic (1.59e-1)" "unprognostic (9.27e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-1)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (9.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" 15.1 2.2 7.5 1.3 9.0 0.6 4.1 7.8 6.4 3.0 3.4 14.1 1.9 6.4 2.9 14.1 6.8 14.6 412.8 5.7 11.5 1.5 24.7 1.5 1.3 11.1 12.0 2.9 11.5 0.4 1.6 1.6 11.3 12.4 2.4 2.0 5.3 4.5 845.6 1.6 4.6 11.9 8.6 0.9 3.2 5.7 8.0 0.8 2.8 435.6 0.7 7.6 2.4 8.6 0.0 0.1 0.2 0.0 0.7 0.7 0.3 0.4 0.5 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.0 13.5 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.0 3.5 6.2 0.3 0.2 0.0 0.3 0.0 0.2 0.0 0.4 0.2 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.2 0.0 0.6 0.0 0.2 7.5 9.0 7.8 6.4 5.7 11.5 11.1 12.0 11.3 8.6 8.0 8.6 1.2 0.0 0.5 49.0 1.7 1.7 2.3 0.7 0.0 2.1 1.0 0.8 1346.0 27.1 1.2 0.0 2.1 0.9 2.7 7.4 0.0 0.6 11.7 1.1 0.4 12.0 0.0 0.8 3.5 6.3 0.1 27.4 6.6 1.0 0.0 3.4 2.5 19.1 0.3 1.7 7.1 0.7 4.1 1.3 2.1 14.1 2.1 1.3 0.0 7.5 1.5 0.2 2.1 24.6 13.5 1.5 88.9 4.1 0.1 0.8 0.5 0.3 2.1 1.6 6.6 24.6 40.8 4.4 5.4 0.1 1.3 2.2 1.3 1.3 0.6 0.6 MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 588.9" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 481.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 137.3;hTERT-HME1: 24.0;HUVEC TERT2: 28.3;OE19: 47.5;RT4: 25.1;TIME: 33.1" HPA039827 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" 65.3 54.7 2.0 2.6 2.4 4.0 22.3 6.3 1.8 17.3 1.3 18.1 16.8 29.4 1.8 41.4 4.7 4.8 588.9 1.8 2.5 5.7 2.4 31.8 6.0 6.7 2.8 5.1 35.1 0.6 1.7 56.6 7.7 19.8 11.8 1.3 18.3 38.2 11.6 9.6 15.4 17.2 1.6 12.4 23.4 2.5 3.5 1.4 3.7 15.5 8.6 84.1 26.9 1.7 6.0 1.7 0.0 10.5 2.3 0.1 3.2 0.9 8.6 1.4 1.7 7.3 4.1 0.1 0.7 0.0 8.9 2.6 0.0 4.4 1.7 0.0 0.2 137.3 1.7 0.1 0.4 0.0 0.1 0.0 3.1 0.3 24.0 0.1 28.3 0.2 1.9 0.0 0.7 2.3 0.0 0.1 0.1 47.5 2.4 0.0 11.4 0.3 0.0 25.1 0.0 4.1 0.6 5.9 0.0 1.2 7.9 0.1 33.1 0.1 2.6 0.4 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.0 3.4 2.0 0.0 0.5 0.0 0.8 0.0 0.2 2.4 2.0 2.4 6.3 1.8 1.8 2.5 6.7 2.8 7.7 1.6 3.5 1.7 22.9 9.6 0.6 0.0 0.3 0.0 10.2 0.0 0.0 0.3 3.0 1.0 481.4 5.7 0.6 25.8 0.0 4.4 0.0 26.9 7.9 32.5 0.1 1.1 3.0 15.1 1.8 1.3 0.0 18.9 2.4 9.8 7.1 3.5 0.0 65.1 4.6 0.2 1.4 0.0 0.0 7.9 0.0 7.9 0.0 0.7 4.7 8.7 0.0 0.0 3.4 0.6 0.0 0.0 0.0 21.5 24.9 17.0 0.0 11.0 18.1 0.3 0.7 0.2 0.0 0.2 8.1 0.0 1.6 0.0 0.0 1.2 0.2 13.2 6.6 22.4 NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 142.2;Kupffer cells: 115.8;Langerhans cells: 109.9;Proximal enterocytes: 167.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 672.4;non-classical monocyte: 583.3" "Lineage enriched" "Detected in all" 5 "monocytes: 672.4" "Cell line enhanced" "Detected in many" "U-2197: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" 19.0 14.6 9.2 30.0 10.0 18.5 37.4 10.9 10.8 23.0 14.1 61.8 30.9 12.9 9.1 28.4 16.4 15.7 19.9 9.5 13.3 40.6 68.4 23.0 48.4 11.2 11.1 8.2 7.6 11.7 7.7 19.4 11.7 70.9 69.9 32.7 31.5 11.4 8.6 22.8 60.7 15.4 9.5 63.8 18.5 3.4 13.2 16.3 15.9 13.0 27.9 20.0 18.4 14.5 11.9 26.6 1.1 0.7 62.4 62.8 1.1 17.5 11.6 11.8 4.0 9.3 41.1 1.0 8.9 43.5 0.4 23.1 34.8 13.4 7.1 17.0 1.3 8.4 19.4 22.6 14.3 31.4 29.6 16.0 10.0 10.3 3.5 18.4 19.1 18.7 9.6 35.9 10.6 43.5 20.2 20.5 13.5 53.4 10.5 13.5 0.4 55.6 12.4 6.7 15.9 2.3 18.1 56.2 5.4 1.8 63.3 54.1 28.8 0.7 1.5 78.6 0.8 8.8 3.8 5.9 14.8 44.5 7.4 48.6 270.1 110.3 62.0 672.4 67.5 58.8 78.4 61.8 143.2 40.4 65.2 54.5 90.3 35.5 583.3 53.2 114.6 233.7 9.2 10.0 10.9 10.8 9.5 13.3 11.2 11.1 11.7 9.5 13.2 14.5 10.6 0.0 7.3 7.2 31.2 11.3 18.8 5.7 4.0 11.5 31.3 14.2 4.4 25.8 10.9 5.5 18.8 24.6 19.5 142.2 13.7 5.7 0.5 12.1 18.1 14.6 48.0 10.8 17.7 8.4 19.2 28.2 3.1 11.9 15.2 3.5 18.5 37.2 39.7 11.8 27.4 45.4 8.2 115.8 109.9 0.0 10.5 80.3 17.8 7.5 77.8 7.7 16.5 5.0 4.8 4.1 46.7 7.5 16.8 55.4 167.7 12.4 27.7 86.9 0.0 31.8 16.7 1.1 0.9 15.9 18.9 13.3 34.8 9.1 24.4 14.0 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 588.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.8;fHDF/TERT166: 7.8;HHSteC: 20.2;HSkMC: 13.5;SCLC-21H: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 13.9 3.2 4.4 6.6 4.1 21.1 12.1 4.7 6.0 23.5 7.0 18.4 19.8 18.8 4.6 7.3 15.2 9.4 10.5 3.9 4.1 7.4 2.6 10.9 10.9 4.7 4.3 16.6 2.3 2.0 6.0 2.3 4.6 13.8 7.1 1.9 4.9 11.5 2.7 5.4 99.3 10.5 4.6 15.3 8.2 8.7 4.4 3.4 5.7 4.1 6.9 12.7 14.5 4.0 0.0 0.0 0.1 0.2 0.5 5.8 1.0 2.3 0.0 2.8 1.3 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.2 0.1 0.9 0.4 0.0 0.2 3.5 20.2 0.0 0.0 13.5 0.0 2.7 0.0 0.1 3.6 0.1 0.0 0.3 0.0 0.2 0.2 0.7 0.0 0.1 0.1 0.1 0.0 1.0 0.2 0.0 10.5 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.8 0.0 0.1 0.1 182.0 21.2 35.9 29.6 14.6 15.8 25.7 23.8 14.8 16.3 29.8 27.0 15.0 3.7 80.2 8.8 0.7 45.2 24.6 4.4 4.1 4.7 6.0 3.9 4.1 4.7 4.3 4.6 4.6 4.4 4.0 19.1 0.0 0.0 0.0 8.0 3.6 3.4 5.6 6.2 2.0 0.8 9.1 1.8 1.5 0.4 0.0 0.0 0.2 9.8 31.3 3.9 0.1 0.8 0.4 5.8 11.1 1.2 2.5 0.3 0.8 0.3 11.4 1.1 0.2 19.7 4.3 16.8 0.4 2.8 10.1 0.4 21.0 2.0 5.6 5.7 2.6 11.8 5.2 16.0 1.0 17.3 12.2 41.2 1.0 0.1 0.2 50.0 18.0 1.1 0.5 588.6 0.5 0.5 0.9 0.0 8.3 11.1 1.6 3.5 1.3 3.3 0.4 11.1 3.9 11.8 0.4 NACAD KIAA0363 ENSG00000136274 "NAC alpha domain containing" O15069 7 45080437-45088969 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.2;pituitary gland: 24.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Oligodendrocytes: 23.1;Peritubular cells: 12.0" "Group enriched" "Detected in many" 7 "glioma: 12.1;testis cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 33.4;SCLC-21H: 25.6;SH-SY5Y: 17.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020981, HPA079208" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" Cytosol Nucleoplasm "HPA020981: AB_2670549, HPA079208: " "unprognostic (5.54e-6)" "unprognostic (1.89e-1)" "unprognostic (8.55e-4)" "unprognostic (7.06e-3)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.61e-1)" "unprognostic (6.91e-2)" "unprognostic (1.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.17e-2)" "unprognostic (8.17e-3)" "unprognostic (2.76e-2)" "unprognostic (7.72e-3)" "unprognostic (2.72e-3)" "unprognostic (9.22e-2)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" 3.3 5.2 23.4 1.2 50.2 0.1 3.2 54.2 42.1 6.2 0.0 8.3 0.7 7.9 0.8 2.0 5.5 1.8 4.5 26.3 34.6 2.1 0.2 2.5 0.7 58.9 48.3 8.9 1.0 0.8 24.3 1.9 58.6 4.3 0.8 3.7 1.7 3.0 1.2 1.7 3.0 4.3 32.7 1.6 3.9 3.7 57.4 0.3 1.3 1.0 0.3 5.0 4.6 84.2 0.0 0.0 2.5 0.1 1.6 0.7 0.1 2.9 3.5 7.7 4.8 0.2 0.1 0.0 2.2 5.1 33.4 0.2 2.2 1.9 2.7 0.0 0.8 0.0 1.7 0.0 1.8 0.0 0.0 1.6 0.0 3.3 0.3 4.1 2.4 0.0 0.0 3.5 2.0 0.0 0.0 0.0 2.3 0.0 2.2 0.0 0.9 0.0 0.3 0.0 25.6 17.7 0.0 0.1 0.1 6.7 0.0 0.1 0.9 0.0 0.0 0.2 0.5 1.8 1.0 0.0 1.5 0.0 5.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.4 50.2 54.2 42.1 26.3 34.6 58.9 48.3 58.6 32.7 57.4 84.2 0.3 0.0 0.0 6.8 0.0 0.6 3.5 0.9 1.2 5.5 0.4 1.8 6.0 0.0 0.2 1.8 0.0 0.1 0.4 0.1 0.0 0.6 2.9 0.5 3.1 0.9 1.2 0.0 4.4 0.2 0.1 3.9 1.1 1.2 1.3 3.9 0.7 0.0 0.1 32.0 5.2 0.0 0.0 0.0 0.0 4.9 6.8 0.7 1.8 1.9 1.0 2.7 0.0 3.0 23.1 0.1 0.0 12.0 0.1 2.3 0.0 0.4 0.8 2.8 6.6 5.3 4.2 1.5 1.4 0.2 0.1 0.1 0.3 9.6 0.1 0.9 NACC2 "BEND9, BTBD14A, BTBD31, MGC23427" ENSG00000148411 "NACC family member 2" Q96BF6 9 136006537-136095289 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 120.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047924, HPA052962" Approved Approved Nucleoli,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA047924: AB_2680212, HPA052962: AB_2681998" "unprognostic (1.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-2)" "unprognostic (8.73e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (9.25e-3)" "unprognostic (2.25e-2)" "unprognostic (1.23e-1)" "unprognostic (4.92e-2)" "unprognostic (1.15e-2)" "unprognostic (2.23e-1)" "prognostic favorable (8.28e-5)" "prognostic favorable (8.63e-4)" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (4.12e-2)" 12.3 11.4 80.9 8.7 100.0 2.0 8.0 115.6 74.1 9.7 26.5 32.7 6.2 20.9 4.1 8.5 12.8 7.2 16.7 52.8 81.0 7.5 9.6 9.5 3.4 113.2 104.9 7.7 7.6 4.6 6.4 2.6 112.3 11.8 3.8 4.9 7.9 17.3 17.0 4.5 9.9 15.6 85.8 8.1 13.6 6.5 120.6 1.0 5.8 6.8 2.0 23.2 7.3 91.9 6.1 32.7 3.6 49.0 15.4 8.6 4.5 14.6 9.7 4.6 1.6 14.0 10.6 0.0 17.1 23.2 7.4 23.3 7.9 7.9 1.5 18.6 7.1 4.1 33.3 17.6 15.6 0.0 7.4 14.4 7.2 4.3 4.3 18.8 13.0 0.0 12.8 0.1 9.0 20.5 0.0 11.6 11.0 9.7 20.2 0.0 3.8 10.0 19.2 6.9 1.2 1.5 20.6 17.0 18.2 16.2 17.4 37.9 21.6 12.3 13.9 10.5 10.1 0.1 0.0 0.3 16.2 1.4 25.2 1.9 2.2 0.8 0.8 1.7 0.3 0.0 0.3 0.7 1.2 0.0 0.2 0.2 2.7 0.2 1.7 0.1 0.2 0.8 80.9 100.0 115.6 74.1 52.8 81.0 113.2 104.9 112.3 85.8 120.6 91.9 14.3 12.8 5.0 69.9 0.8 4.6 4.9 9.0 3.4 3.4 6.7 5.6 28.5 7.2 7.9 5.5 0.0 0.7 7.0 12.4 0.0 12.6 76.2 18.9 9.8 18.5 2.4 1.7 2.5 13.4 2.1 10.9 7.7 6.0 2.5 1.5 17.9 33.2 7.8 3.3 21.1 4.4 0.0 38.4 8.0 305.5 18.0 16.6 5.4 21.5 45.3 17.1 12.3 40.7 45.1 18.3 9.2 19.2 2.1 11.8 6.7 13.6 12.5 1.9 26.3 14.0 15.8 2.4 12.6 6.8 5.1 0.4 5.7 1.4 5.3 7.6 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Enhanced Nucleoplasm No No 410000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favorable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 39.4 28.9 16.2 49.3 15.0 67.8 36.5 13.8 18.2 49.9 29.8 133.5 52.2 28.5 33.5 51.4 29.4 34.2 46.3 15.1 17.0 32.8 67.0 45.9 59.5 16.2 17.2 26.2 67.6 20.4 42.5 31.7 18.4 106.4 129.2 8.3 120.0 19.7 34.2 29.2 47.8 29.0 15.1 53.3 76.1 27.2 17.2 18.8 27.3 17.4 60.5 47.5 41.5 17.2 387.9 111.8 32.5 94.5 64.0 68.8 70.5 120.9 93.7 96.3 78.3 134.8 53.6 118.1 57.2 133.3 101.9 134.1 61.0 103.6 80.0 95.7 91.0 70.3 128.4 271.9 176.3 80.3 55.3 58.4 69.1 102.9 116.4 111.8 104.3 57.9 129.9 119.8 71.2 265.0 54.1 114.9 56.2 277.5 143.3 103.4 89.0 121.5 78.2 116.6 65.7 34.4 77.8 414.4 107.2 35.8 137.6 85.3 274.2 74.8 72.5 193.4 125.8 110.7 99.3 45.7 88.4 95.9 59.6 30.9 190.9 29.5 34.9 237.6 53.4 55.6 45.5 36.8 194.7 54.9 48.8 33.7 77.4 38.9 217.0 178.8 58.3 91.4 16.2 15.0 13.8 18.2 15.1 17.0 16.2 17.2 18.4 15.1 17.2 17.2 46.7 28.9 54.9 3.6 57.0 70.1 134.0 183.0 30.7 11.4 61.6 45.5 25.3 42.9 206.3 22.0 18.8 86.7 50.2 234.3 70.5 49.4 42.8 63.4 37.9 63.4 64.9 18.7 6.7 100.7 159.2 50.6 99.4 55.8 43.8 29.5 34.2 33.6 160.0 10.1 7.2 362.7 95.6 67.7 107.6 71.5 32.3 89.8 129.9 6.5 53.1 14.1 14.4 2.0 3.1 70.9 181.0 26.4 141.1 213.6 66.5 68.3 204.5 8.0 13.1 32.9 91.3 10.5 21.9 42.0 61.7 150.8 50.6 44.6 260.1 223.3 NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.4;retina: 40.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Excitatory neurons: 27.9;Horizontal cells: 62.2;Inhibitory neurons: 57.1" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cell line enhanced" "Detected in some" "AF22: 13.6;HAP1: 13.2;NTERA-2: 24.0;SuSa: 20.7;U-2197: 16.1" "Low region specificity" "Detected in all" HPA026075 Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA026075: AB_1854301" "unprognostic (7.18e-2)" "unprognostic (1.81e-2)" "unprognostic (9.26e-2)" "unprognostic (4.83e-4)" "unprognostic (3.06e-1)" "unprognostic (1.28e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.75e-3)" "unprognostic (5.01e-2)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-4)" 2.5 13.4 65.2 2.8 53.3 1.2 2.6 46.9 103.4 19.3 11.2 3.2 1.5 12.1 5.6 1.3 10.0 5.4 11.3 50.5 62.9 3.3 1.3 1.8 2.5 45.3 62.7 16.7 1.3 1.0 18.1 1.5 54.4 4.4 2.4 40.9 1.4 5.3 0.4 1.7 2.0 8.2 40.6 4.6 1.4 16.6 46.9 1.1 5.6 1.2 1.3 3.5 2.8 47.5 0.0 0.2 13.6 9.9 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 7.6 0.3 0.1 13.2 0.0 0.0 0.0 0.3 6.4 0.0 0.2 0.7 0.0 0.4 6.1 0.0 0.6 6.2 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 24.0 0.0 5.7 0.0 10.5 0.0 0.4 0.1 0.1 1.4 0.0 0.0 0.2 20.7 0.0 0.7 0.0 7.5 10.9 16.1 0.7 10.2 4.5 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.7 0.0 2.6 0.9 0.0 0.0 4.1 2.9 0.1 3.1 0.0 0.0 0.8 0.9 65.2 53.3 46.9 103.4 50.5 62.9 45.3 62.7 54.4 40.6 46.9 47.5 0.8 0.0 0.0 11.8 0.3 0.6 0.3 0.0 0.0 41.8 0.2 1.9 8.3 0.0 0.6 0.0 6.2 0.2 0.8 0.0 17.6 0.1 1.2 0.3 9.9 1.4 0.0 1.3 27.9 0.0 0.2 7.6 0.0 0.3 5.7 7.4 1.1 0.0 0.4 62.2 57.1 0.0 0.0 0.0 0.9 2.2 11.8 0.3 5.4 9.4 0.2 16.6 0.0 16.6 21.2 0.2 0.0 19.5 0.1 0.0 0.0 0.5 1.5 12.9 0.0 6.6 4.0 5.7 7.4 0.0 0.4 0.3 1.6 16.4 0.0 0.0 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.2;Paneth cells: 32.7;Respiratory ciliated cells: 32.0" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB017782, HPA043704" Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB017782: , HPA043704: AB_2678625" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.6 1.5 0.5 5.4 0.7 3.2 5.9 0.8 0.9 6.5 0.8 14.2 11.7 2.4 15.2 2.5 4.4 3.6 1.8 0.5 0.7 5.7 10.4 3.5 6.0 1.2 0.7 2.9 1.8 1.1 1.0 4.1 0.8 7.3 12.8 0.3 1.9 2.9 0.4 2.4 8.9 3.6 0.8 4.1 4.9 1.8 0.8 4.6 2.1 1.5 6.7 4.5 1.3 1.0 22.6 2.7 2.5 3.3 6.3 6.3 5.3 8.0 8.5 8.8 10.2 4.0 4.7 11.0 6.2 5.2 8.1 3.6 4.5 5.4 8.9 10.3 2.3 7.6 3.0 3.0 6.0 3.3 9.7 5.2 6.5 6.0 0.5 2.2 7.9 9.3 6.6 2.9 10.0 4.0 9.8 10.3 2.4 17.8 3.4 4.9 2.5 4.3 9.3 12.6 1.3 1.7 0.3 9.5 5.5 5.2 7.7 9.7 8.5 5.3 3.1 8.0 1.3 2.0 4.0 9.3 4.6 7.5 2.4 5.4 4.6 9.4 3.3 5.3 2.4 4.4 3.4 3.4 6.1 3.9 3.2 3.9 8.2 6.3 5.4 3.5 6.3 2.7 0.5 0.7 0.8 0.9 0.5 0.7 1.2 0.7 0.8 0.8 0.8 1.0 4.6 0.0 3.6 0.7 4.7 0.4 0.8 9.1 1.2 0.0 3.5 1.9 1.6 0.0 11.3 5.5 0.0 5.9 2.3 24.2 1.9 5.7 10.8 3.9 3.2 3.0 3.6 0.8 0.8 6.9 7.7 2.1 3.6 2.8 2.5 1.1 2.2 12.7 7.2 0.0 0.2 10.7 8.2 6.3 2.6 2.2 4.1 5.3 3.6 1.9 4.9 2.5 4.1 0.0 0.5 5.8 32.7 5.7 2.6 2.3 12.7 16.6 32.0 0.0 0.0 0.7 3.4 4.2 0.6 2.2 0.6 10.9 4.1 3.2 8.4 2.5 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 453.4;skin 1: 273.2;vagina: 181.7" "Cell type enriched" "Detected in some" 12 "monocytes: 563.9" "Group enriched" "Detected in many" 4 "cervical cancer: 42.8;head and neck cancer: 48.5;melanoma: 28.3;urothelial cancer: 33.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enriched" "Detected in some" 10 "SK-BR-3: 30.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in some" HPA052812 Approved NA NA 400000 "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA052812: AB_2681960" "unprognostic (3.56e-3)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.59e-3)" "unprognostic (3.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.37e-3)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (2.04e-2)" "unprognostic (1.90e-1)" "unprognostic (6.37e-6)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-1)" 0.3 0.2 1.3 2.1 0.9 1.0 6.3 1.9 1.8 97.0 0.0 0.4 2.0 0.6 0.8 453.4 1.1 0.8 0.4 1.0 0.8 2.8 0.2 0.4 2.7 1.0 0.9 0.4 8.8 1.4 0.4 1.1 1.3 1.4 1.9 1.7 54.0 1.2 0.9 273.2 0.7 0.5 0.9 1.4 0.5 0.5 1.0 4.1 0.6 0.0 124.9 5.2 181.7 1.4 0.2 0.2 1.1 0.2 0.1 0.7 2.4 0.1 0.0 0.1 0.2 0.5 0.5 0.7 2.3 0.4 0.2 1.0 1.7 0.7 0.5 0.0 0.4 0.2 0.9 0.1 0.2 0.5 0.3 0.5 0.5 0.1 0.3 0.3 0.3 0.5 0.4 0.2 0.3 0.1 0.2 0.2 0.7 0.2 0.2 0.2 0.4 0.4 0.1 0.6 0.6 1.0 2.9 30.8 0.2 0.9 0.4 0.9 0.2 0.2 0.2 0.2 0.5 0.2 0.2 0.6 0.6 0.2 0.5 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 1.3 0.9 1.9 1.8 1.0 0.8 1.0 0.9 1.3 0.9 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 1.6 8.5 0.0 0.3 4.7 2.4 0.3 0.0 30.8 3.7 0.0 0.4 0.2 0.1 0.0 2.7 0.0 0.7 0.4 0.2 0.0 0.0 0.0 2.3 3.1 1.0 0.0 2.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 6.1 0.0 4.7 0.2 0.0 0.7 1.8 0.0 563.9 0.3 0.0 0.0 0.0 4.2 0.7 0.0 1.2 1.1 0.0 0.1 1.6 0.0 0.0 0.1 2.0 0.1 0.5 7.3 7.1 11.1 0.2 0.1 0.0 46.4 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NECAB1 EFCBP1 ENSG00000123119 "N-terminal EF-hand calcium binding protein 1" Q8N987 8 90791741-90959393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 59.4;choroid plexus: 24.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 374.6;Oligodendrocytes: 307.8" "Cancer enhanced" "Detected in many" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 4.0;MOLT-4: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210" Enhanced Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB068208: AB_2665671, CAB068209: AB_2665672, CAB068210: AB_2665673, HPA023252: AB_1848013, HPA023629: AB_1848014, HPA025963: AB_1848015, HPA031262: AB_2673815" "unprognostic (8.09e-3)" "unprognostic (3.78e-1)" "unprognostic (8.17e-3)" "unprognostic (5.96e-5)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-3)" "unprognostic (8.38e-2)" "unprognostic (1.78e-3)" "unprognostic (2.60e-1)" "unprognostic (2.25e-2)" "unprognostic (2.57e-2)" "unprognostic (2.19e-3)" "unprognostic (4.45e-3)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (5.39e-3)" 2.2 3.5 20.5 0.9 28.2 2.4 1.6 6.7 59.4 3.3 24.3 8.3 0.6 5.5 3.1 2.2 3.4 1.8 9.0 33.2 20.0 2.3 0.2 5.4 0.4 8.4 12.7 3.2 0.3 0.5 3.8 1.7 7.2 3.3 0.1 0.9 1.3 0.8 0.3 1.7 1.6 0.2 12.4 1.4 2.9 4.8 27.1 0.0 2.0 0.1 0.0 4.5 2.4 41.2 0.1 0.1 1.4 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.0 0.0 0.0 2.7 4.0 1.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 3.9 0.0 1.0 2.8 2.8 0.0 3.7 4.2 2.2 0.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.8 2.8 0.1 0.0 1.4 1.7 0.0 0.1 1.0 2.5 2.4 0.0 1.0 3.8 2.4 2.0 2.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 20.5 28.2 6.7 59.4 33.2 20.0 8.4 12.7 7.2 12.4 27.1 41.2 0.8 19.2 69.7 20.9 0.0 0.5 0.2 0.1 0.0 4.8 0.2 0.8 64.0 0.0 2.5 12.9 0.0 0.0 0.4 0.1 0.0 0.0 4.4 0.4 2.2 3.4 0.0 12.2 374.6 0.2 0.0 6.4 0.0 0.2 1.3 0.2 0.7 0.0 0.1 0.0 63.5 0.0 0.0 0.0 0.6 1.4 2.5 0.3 3.6 38.4 0.0 0.4 0.0 17.6 307.8 0.1 0.0 2.2 0.1 0.1 0.0 9.0 0.0 0.5 6.6 1.0 6.1 4.6 2.2 0.1 0.9 0.0 0.2 0.5 0.0 0.0 NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA044785: AB_2679086, HPA070595: AB_2732158, HPA071786: AB_2732186" "unprognostic (8.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.19e-5)" "unprognostic (3.13e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (6.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" 10.2 55.9 20.1 2.2 21.2 1.5 10.4 18.9 33.9 11.8 20.4 14.4 13.6 9.1 6.9 8.9 10.9 4.5 45.7 21.7 21.2 13.3 13.3 11.1 2.3 23.3 19.1 41.2 19.1 17.5 10.3 3.9 24.4 27.2 4.4 6.5 13.6 7.8 60.3 6.9 10.6 3.7 16.6 6.5 30.5 10.6 23.2 1.9 19.2 31.7 1.7 14.6 10.0 22.3 8.2 7.1 5.1 10.5 4.0 7.8 24.6 11.2 4.2 7.1 6.2 33.2 5.3 9.1 26.2 6.6 16.7 9.7 5.3 3.3 2.6 3.2 7.7 8.7 30.7 39.3 10.5 2.1 8.0 9.7 4.8 6.6 2.1 7.6 4.8 4.8 12.6 4.8 9.3 12.5 3.3 8.6 2.2 8.7 17.5 9.7 13.3 15.9 6.6 6.1 32.4 9.0 26.1 28.7 12.0 5.6 36.6 10.4 4.0 8.6 12.4 11.3 12.7 17.7 7.8 17.1 16.9 4.0 3.8 0.0 1.3 1.8 0.3 1.3 0.9 0.2 0.6 0.3 1.2 0.9 0.4 0.1 0.0 1.2 3.5 0.0 1.6 0.6 20.1 21.2 18.9 33.9 21.7 21.2 23.3 19.1 24.4 16.6 23.2 22.3 5.4 16.0 45.5 14.7 4.1 3.1 6.5 2.7 8.6 19.4 20.5 11.6 29.9 10.0 5.9 5.5 8.4 20.6 3.8 22.5 33.2 3.7 93.1 5.7 7.2 2.4 19.9 4.0 13.0 7.5 26.1 12.5 26.5 5.4 3.8 14.0 2.2 9.1 8.9 8.4 14.5 16.2 4.1 6.0 6.2 54.0 26.4 5.5 12.4 1.0 3.6 18.2 2.1 6.0 4.5 4.4 15.1 23.7 11.7 14.2 45.9 12.2 3.8 20.8 6.6 9.2 12.1 20.5 20.6 9.3 3.1 20.7 5.4 23.9 20.0 10.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NEFH "NF-H, NFH" ENSG00000100285 "Neurofilament heavy" P12036 22 29480218-29491390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 544.0;prostate: 245.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 20.9;monocytes: 34.6;Prostatic glandular cells: 44.0;Spermatogonia: 29.5;Theca cells: 49.7" "Cancer enriched" "Detected in many" 4 "prostate cancer: 130.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 5 "monocytes: 4.7" "Cell line enriched" "Detected in many" 5 "SiHa: 182.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1241.2" "CAB007786, HPA061615" Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "CAB007786: AB_598179, HPA061615: AB_2684568" "prognostic favorable (2.33e-6)" "unprognostic (6.17e-3)" "unprognostic (9.74e-2)" "unprognostic (3.20e-2)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (2.63e-4)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (6.42e-2)" "unprognostic (5.85e-2)" "unprognostic (6.64e-3)" "unprognostic (1.57e-3)" "unprognostic (1.54e-1)" "unprognostic (2.59e-1)" "unprognostic (1.31e-2)" "unprognostic (1.47e-1)" 0.6 21.1 17.7 1.6 18.9 0.6 1.4 143.1 544.0 0.6 0.0 1.4 0.4 0.5 0.7 0.3 0.5 0.4 0.4 7.8 57.3 0.9 0.3 0.4 0.9 494.1 56.2 20.0 0.3 0.9 15.4 0.6 376.1 245.9 0.5 39.6 0.9 0.6 0.3 0.2 0.9 1.0 58.3 1.2 0.6 7.7 172.9 0.7 0.3 0.3 1.0 0.4 1.2 147.3 0.0 0.0 2.4 0.6 0.1 0.3 1.8 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.8 1.9 9.5 0.1 0.0 0.0 0.0 9.0 34.2 0.1 24.2 0.0 1.4 0.2 10.5 3.5 0.0 0.5 0.0 0.0 1.3 0.0 28.0 0.0 11.7 0.0 12.0 1.2 17.4 0.0 0.0 0.1 0.1 1.9 0.0 0.0 1.5 19.5 182.2 0.1 0.0 5.9 0.0 9.9 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.0 0.4 2.7 0.8 0.1 0.5 0.4 0.6 0.0 0.1 0.5 0.0 0.2 4.7 0.1 0.2 0.6 17.7 18.9 143.1 544.0 7.8 57.3 494.1 56.2 376.1 58.3 172.9 147.3 0.7 0.0 0.0 3.9 1.0 0.1 1.0 0.1 2.2 3.2 1.4 5.3 0.9 1.5 0.0 1.8 2.1 1.4 1.6 0.5 0.0 0.2 0.4 0.3 7.7 1.0 0.0 5.9 13.6 0.4 1.1 2.4 0.0 0.8 1.3 8.8 0.0 0.0 5.6 8.4 20.9 0.0 0.0 4.2 2.3 1.0 5.9 5.2 1.8 5.6 34.6 3.6 0.0 2.0 2.6 0.3 0.0 3.0 1.7 44.0 0.2 1.0 0.0 9.9 6.6 1.3 2.0 4.4 29.5 3.0 0.1 0.4 1.7 49.7 0.2 0.7 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 777.3;Oligodendrocyte precursor cells: 606.7;Peritubular cells: 438.5;Skeletal myocytes: 513.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" 23.0 12.4 28.4 5.2 37.7 10.0 15.1 75.9 24.6 18.3 31.8 14.2 7.2 8.9 11.7 18.8 15.6 14.3 16.9 28.4 31.3 10.8 40.5 8.4 5.1 51.5 33.4 15.7 13.5 10.9 5.4 4.3 34.9 15.0 9.1 4.2 17.5 11.6 13.8 8.7 6.4 13.2 37.3 9.4 9.7 5.8 33.6 8.6 27.4 15.8 6.8 13.8 10.3 27.1 5.0 6.8 1.0 74.2 31.8 20.2 0.2 1.6 5.1 1.6 2.4 0.4 4.8 10.9 4.8 2.7 0.7 7.2 3.1 15.4 0.9 23.4 6.6 0.4 15.2 4.8 7.3 1.2 1.8 25.7 14.9 6.8 27.6 5.5 19.1 3.0 5.1 16.9 1.5 3.6 0.3 0.3 2.9 6.9 6.6 1.1 6.9 18.2 4.3 13.1 4.8 5.7 4.1 28.2 10.3 0.8 30.2 0.5 15.5 1.3 8.5 15.2 3.1 1.2 3.1 0.1 1.7 0.2 1.7 3.2 2.7 1.5 1.9 1.9 2.9 0.6 2.3 3.0 1.3 0.3 2.2 2.7 0.1 0.5 2.5 1.0 0.1 1.8 28.4 37.7 75.9 24.6 28.4 31.3 51.5 33.4 34.9 37.3 33.6 27.1 232.1 35.3 44.7 777.3 4.4 85.0 68.8 72.1 220.9 42.6 140.7 107.4 192.9 148.7 68.1 47.8 2.1 5.7 8.1 28.4 27.4 38.0 28.9 85.8 69.8 132.7 25.2 163.7 142.3 47.8 1.1 265.6 30.5 68.2 27.3 11.6 197.0 304.5 14.8 42.1 125.7 46.8 36.7 60.8 42.6 26.4 408.8 19.2 46.2 259.5 14.9 150.2 5.2 606.7 431.3 20.8 37.6 438.5 8.0 53.0 19.1 109.9 82.6 6.9 144.7 513.1 133.7 5.0 13.5 148.4 76.3 1.6 15.0 34.9 69.7 57.1 NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.4;esophagus: 2.3;retina: 2.1;skin 1: 3.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 7.9;Spermatocytes: 5.1;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 58.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 37: Myocytes - Muscle contraction" "Nuclear bodies" Nucleoplasm "HPA055238: AB_2682752" "unprognostic (2.20e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (9.55e-2)" "unprognostic (2.80e-3)" "unprognostic (1.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-1)" 0.0 0.0 2.0 0.0 1.4 0.0 0.1 5.9 2.1 0.3 0.2 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 3.2 4.0 0.0 0.0 0.2 0.0 3.8 5.1 0.0 0.0 0.0 0.2 0.0 7.4 0.2 0.0 2.1 0.4 0.1 0.2 3.3 0.0 0.0 2.5 0.0 0.2 0.4 6.7 0.0 0.0 0.0 0.0 0.0 0.7 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 5.9 2.1 3.2 4.0 3.8 5.1 7.4 2.5 6.7 3.0 0.0 0.0 0.0 0.3 0.0 2.8 2.8 3.3 14.8 3.9 0.0 0.6 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 1.8 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.5 7.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.4 0.0 3.5 0.3 5.1 3.4 7.0 2.3 0.0 0.0 0.0 0.0 0.4 NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 164.1" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.1" "Cell line enhanced" "Detected in many" "HDLM-2: 83.8;Karpas-707: 85.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA028172: AB_10599602, HPA028231: AB_10601886, HPA028657: AB_10601680" "unprognostic (4.61e-3)" "unprognostic (3.45e-2)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-3)" "unprognostic (9.01e-3)" "unprognostic (4.38e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (4.52e-4)" 18.2 7.8 1.4 38.9 1.6 8.8 24.0 1.5 1.9 14.8 3.1 104.7 8.5 24.2 6.2 61.2 22.1 27.7 164.1 1.5 2.0 3.3 2.7 18.1 11.3 3.9 2.4 4.9 85.7 4.2 2.1 6.2 3.1 59.6 15.9 0.8 100.6 43.1 60.9 8.8 18.5 41.0 2.8 12.3 58.9 1.9 2.2 12.2 15.3 41.2 17.3 105.8 14.6 3.2 42.0 0.5 0.2 0.1 28.0 42.2 1.6 21.1 42.9 17.7 22.3 0.0 17.3 0.0 13.6 54.2 4.6 46.0 2.4 1.5 28.4 83.8 3.2 17.5 8.2 0.0 65.2 57.2 19.1 39.1 65.3 52.1 62.4 12.6 0.1 6.3 4.2 85.5 0.5 0.2 1.9 10.0 11.1 0.0 4.3 13.3 9.9 0.8 24.5 0.8 2.3 2.1 0.4 0.1 29.9 7.0 9.0 17.9 3.3 35.0 0.1 6.3 43.5 71.1 30.2 8.7 68.8 23.4 35.3 20.4 3.6 10.9 5.1 2.1 4.4 1.0 4.7 5.0 5.2 0.3 0.4 1.8 72.1 5.7 0.8 0.5 11.9 2.2 1.4 1.6 1.5 1.9 1.5 2.0 3.9 2.4 3.1 2.8 2.2 3.2 20.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 692.7 0.0 0.0 0.0 0.0 0.4 52.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.2 24.7 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.4 27.4 0.0 0.0 0.0 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NIPAL3 "DJ462O23.2, NPAL3" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Oligodendrocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" 8.4 7.4 49.6 8.4 67.3 8.4 12.9 67.7 58.5 9.6 25.8 13.8 11.3 6.2 11.7 15.9 14.6 8.9 12.8 43.6 58.1 13.8 3.5 13.9 11.6 61.8 58.6 7.2 17.1 21.9 7.3 3.5 65.0 55.9 14.4 27.7 15.2 7.6 5.9 14.0 12.7 12.3 56.1 7.8 14.8 4.9 65.0 13.2 29.2 11.9 13.1 8.0 10.4 88.5 32.4 12.1 1.1 4.2 18.9 20.7 4.5 101.8 71.7 35.0 26.2 4.5 36.4 15.4 30.2 55.2 7.3 31.5 12.5 37.1 37.3 29.5 38.1 16.0 18.5 5.4 17.7 14.2 14.4 20.7 36.1 22.3 75.7 34.8 12.2 27.5 9.5 9.7 22.4 7.2 11.5 6.6 8.3 15.4 34.0 5.5 0.1 17.1 41.6 10.1 44.6 4.3 13.1 19.5 26.9 8.6 26.0 10.6 17.9 31.5 6.7 10.9 22.9 29.4 24.1 5.4 21.4 26.8 28.8 16.9 5.8 7.9 16.7 5.7 16.9 22.1 28.8 22.5 11.2 20.1 38.9 24.8 2.5 15.6 4.2 14.6 31.8 16.0 49.6 67.3 67.7 58.5 43.6 58.1 61.8 58.6 65.0 56.1 65.0 88.5 17.1 48.1 27.5 8.8 15.4 9.2 13.5 25.7 14.8 50.3 15.9 12.2 25.9 15.7 24.7 40.5 110.5 3.8 32.1 25.0 3.9 13.1 3.6 11.0 3.5 10.2 18.7 26.1 29.3 15.5 4.7 7.4 16.8 18.3 13.3 10.5 9.3 3.8 4.5 13.5 32.2 16.7 16.2 7.0 7.8 8.0 4.1 5.5 14.2 10.3 8.6 18.7 23.7 24.6 91.8 22.6 22.6 5.3 16.0 34.5 33.2 4.5 16.5 53.6 0.0 4.4 5.9 2.6 6.0 20.0 16.3 4.2 25.3 8.2 17.2 20.9 NIPSNAP3B FLJ11275 ENSG00000165028 "Nipsnap homolog 3B" Q9BS92 9 104764129-104777764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.4;tongue: 19.5" "Cell type enhanced" "Detected in many" "Adipocytes: 11.8;Cardiomyocytes: 21.6;Excitatory neurons: 10.7;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "REH: 3.0;SH-SY5Y: 2.1;THP-1: 2.2;U-266/70: 2.3" HPA042491 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042491: AB_2678023" "unprognostic (1.72e-2)" "unprognostic (1.47e-2)" "unprognostic (9.76e-2)" "unprognostic (1.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (1.41e-3)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (4.25e-5)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (5.61e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (4.81e-2)" 6.6 5.1 1.8 1.1 1.9 0.7 4.3 1.2 2.2 2.3 1.6 1.1 0.5 3.1 3.4 1.0 1.9 1.3 12.8 1.9 2.0 1.5 0.5 1.4 1.5 1.5 1.5 3.3 1.9 1.0 2.7 3.0 1.6 2.7 0.9 2.5 1.4 3.6 20.4 1.3 1.2 1.6 1.2 2.0 1.1 1.0 1.8 0.8 2.0 19.5 1.8 0.9 1.5 1.5 0.0 0.3 0.4 0.1 0.4 0.4 0.7 0.1 0.2 0.2 0.1 0.3 0.3 0.8 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.0 0.5 1.4 1.2 0.1 0.4 0.2 0.4 0.4 0.1 0.3 0.0 0.5 0.1 0.7 1.2 0.0 0.0 0.2 0.6 1.2 0.2 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.9 2.1 1.2 0.0 0.1 0.2 1.1 2.2 0.1 0.2 0.4 0.2 0.1 2.3 0.8 0.2 0.0 0.2 0.0 2.8 0.0 0.6 0.0 0.1 0.1 0.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 1.8 1.9 1.2 2.2 1.9 2.0 1.5 1.5 1.6 1.2 1.8 1.5 11.8 0.0 1.1 2.0 8.5 0.4 1.5 0.8 1.2 4.0 0.9 1.7 21.6 0.0 0.3 3.7 0.0 0.8 0.1 0.0 5.9 0.7 0.0 2.2 2.0 3.4 1.2 5.9 10.7 0.2 0.2 3.9 2.6 1.2 1.3 2.5 6.1 0.3 6.2 0.0 9.8 0.3 4.1 0.9 3.9 0.9 2.5 3.0 0.0 16.9 4.1 1.2 0.0 4.5 1.1 0.2 0.0 6.8 2.3 0.3 0.0 0.4 3.2 0.5 0.0 2.0 3.7 0.8 1.1 1.7 0.9 0.8 1.1 0.8 0.2 0.2 NKD1 ENSG00000140807 "NKD inhibitor of WNT signaling pathway 1" Q969G9 16 50548396-50649249 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.6" "Cell type enhanced" "Detected in many" "Microglial cells: 45.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 27.4;Smooth muscle cells: 13.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;CACO-2: 13.6;Hep G2: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041352, HPA049413" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center" "HPA041352: AB_2677428, HPA049413: AB_2680753" "unprognostic (1.58e-3)" "unprognostic (1.24e-2)" "unprognostic (1.94e-1)" "unprognostic (6.02e-3)" "unprognostic (5.59e-3)" "unprognostic (9.80e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (5.25e-3)" "unprognostic (2.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (6.88e-4)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (3.30e-2)" "unprognostic (3.44e-2)" 1.7 0.7 7.3 0.7 7.9 0.1 1.0 7.1 4.6 2.5 2.1 4.8 1.1 6.0 4.2 3.2 4.7 2.8 0.5 4.0 5.5 1.6 0.6 6.8 0.4 9.3 12.8 2.9 1.2 0.2 0.4 1.9 7.2 3.5 1.4 0.7 0.5 2.7 0.3 2.0 2.0 5.7 7.0 1.5 2.1 1.1 14.6 0.7 0.3 0.2 0.5 2.2 1.2 7.7 0.0 0.1 6.3 0.5 2.4 0.0 0.2 0.0 0.0 0.0 0.0 13.6 0.3 0.0 0.2 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.7 0.7 0.0 36.5 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.1 1.4 0.5 0.6 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 7.1 4.6 4.0 5.5 9.3 12.8 7.2 7.0 14.6 7.7 0.3 0.0 0.0 4.2 0.2 1.5 1.2 0.2 0.0 2.1 0.3 0.8 0.8 0.0 0.5 0.0 6.2 2.5 0.7 0.2 0.0 0.4 7.4 0.5 2.0 0.9 1.8 0.4 0.4 0.4 0.4 3.8 1.5 0.7 0.0 3.7 0.4 1.7 0.4 0.0 1.0 0.5 0.0 0.0 3.0 2.2 1.8 0.8 8.8 45.9 0.2 6.7 0.0 57.3 27.4 0.3 0.0 3.4 0.5 0.9 0.2 0.1 0.1 0.8 13.1 0.4 13.4 1.1 7.1 0.6 1.1 2.3 2.4 0.0 0.5 1.4 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NKX3-1 "BAPX2, NKX3.1, NKX3A" ENSG00000167034 "NK3 homeobox 1" Q99801 8 23678697-23682938 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 303.3" "Group enriched" "Detected in many" 6 "Basal prostatic cells: 51.0;Prostatic glandular cells: 124.8" "Cancer enriched" "Detected in many" 65 "prostate cancer: 392.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 54.0;neutrophil: 51.6" "Lineage enriched" "Detected in many" 21 "granulocytes: 54.0" "Cell line enhanced" "Detected in many" "GAMG: 25.7;SiHa: 26.1;U-138 MG: 25.8;U-251 MG: 23.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA025693, HPA078571" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA025693: AB_1854522, HPA078571: AB_2732384" "unprognostic (1.47e-2)" "unprognostic (4.03e-2)" "unprognostic (2.67e-1)" "unprognostic (5.87e-2)" "unprognostic (2.56e-6)" "unprognostic (6.90e-3)" "unprognostic (1.13e-1)" "unprognostic (4.11e-3)" "unprognostic (9.42e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.37e-2)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" 1.7 3.9 1.0 1.5 1.2 2.2 2.1 1.4 1.4 1.1 0.9 1.4 1.4 1.5 1.3 3.7 1.8 1.1 2.6 1.2 1.6 1.4 4.1 1.4 1.2 1.8 1.5 2.8 1.8 1.0 0.9 0.8 1.6 303.3 0.5 1.7 62.0 1.8 3.2 0.4 1.0 1.9 1.7 0.8 1.4 24.0 1.5 0.5 0.7 3.9 1.6 2.9 1.9 1.4 4.9 3.7 0.0 8.7 3.1 0.7 7.1 6.7 4.2 13.8 16.2 2.1 5.5 0.0 1.0 5.0 25.7 1.2 3.5 7.6 10.9 0.0 1.8 3.4 2.6 5.5 6.0 0.0 1.2 1.2 2.0 14.0 0.8 8.5 0.7 20.1 0.2 0.0 5.5 1.6 11.8 1.0 2.0 0.0 2.6 0.0 5.5 0.5 0.8 5.7 1.6 0.4 26.1 4.8 0.4 9.9 3.5 0.5 0.9 25.8 9.1 2.0 23.0 0.0 0.0 0.0 12.5 2.6 3.2 10.2 0.0 54.0 1.0 0.1 0.2 2.2 0.4 1.0 0.1 1.8 1.4 2.5 51.6 0.6 0.1 0.0 0.0 0.3 1.0 1.2 1.4 1.4 1.2 1.6 1.8 1.5 1.6 1.7 1.5 1.4 6.0 3.2 5.3 0.0 4.1 5.6 51.0 4.1 4.6 3.7 13.5 6.5 9.8 1.5 4.7 0.0 8.4 0.3 0.3 1.0 0.0 2.7 2.7 1.3 2.0 6.8 6.6 0.0 0.4 7.0 1.4 9.1 5.1 2.2 0.0 0.8 4.6 4.9 0.3 3.3 0.4 1.2 2.0 0.3 9.4 6.1 2.1 2.5 1.8 0.0 0.6 4.9 0.0 0.5 0.1 5.2 0.1 6.4 1.0 124.8 0.4 0.7 1.4 4.5 0.0 11.4 5.1 1.8 2.1 2.5 2.0 0.3 2.5 0.8 1.1 12.2 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 NLRC5 "CLR16.1, FLJ21709, NOD27" ENSG00000140853 "NLR family CARD domain containing 5" Q86WI3 16 56989485-57083531 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.6;lymphoid tissue: 32.8" "Cell type enhanced" "Detected in many" "dendritic cells: 35.8;Distal enterocytes: 43.2;Gastric mucus-secreting cells: 41.8;NK-cells: 39.1;T-cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 94.2;NB-4: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060405, HPA074724" Supported Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Centrosome "HPA060405: AB_2684277, HPA074724: " "unprognostic (9.66e-2)" "prognostic favorable (9.69e-4)" "unprognostic (1.64e-2)" "unprognostic (1.23e-2)" "unprognostic (3.12e-1)" "unprognostic (9.27e-3)" "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "unprognostic (2.24e-2)" "prognostic favorable (2.30e-4)" "unprognostic (2.69e-1)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.99e-2)" "unprognostic (3.91e-2)" "unprognostic (5.06e-2)" "unprognostic (2.75e-3)" 5.8 3.6 2.4 24.1 2.9 34.6 2.9 2.1 2.6 2.7 1.2 8.5 6.0 4.2 1.5 5.5 2.7 8.4 4.1 1.8 2.5 2.4 2.6 11.3 28.9 7.4 3.1 2.8 2.6 3.0 4.8 2.7 5.5 2.9 6.8 0.7 8.6 2.5 3.1 13.6 8.8 6.0 3.3 32.8 9.2 1.2 4.1 10.6 2.8 4.8 17.3 7.0 2.7 3.7 11.3 2.1 0.3 0.8 0.7 3.6 0.1 6.1 9.4 19.1 18.4 0.0 19.0 22.9 4.5 10.0 7.5 7.3 2.4 0.6 2.1 1.0 0.7 94.2 21.8 2.3 6.5 3.3 5.4 7.0 0.2 15.6 1.7 6.1 7.5 3.2 0.1 4.5 4.0 0.4 5.2 51.8 0.1 0.3 2.0 24.5 6.9 9.4 2.1 0.9 0.7 0.8 12.4 1.1 2.6 0.0 1.3 12.3 9.7 9.1 3.2 33.7 5.1 9.0 5.0 23.9 16.3 6.9 1.7 7.2 3.8 12.6 5.8 1.9 3.5 4.6 3.4 5.7 1.5 2.7 2.1 2.3 8.5 2.3 2.3 1.1 4.1 3.0 2.4 2.9 2.1 2.6 1.8 2.5 7.4 3.1 5.5 3.3 4.1 3.7 29.8 0.0 11.2 6.2 28.0 6.8 0.9 1.1 2.2 0.9 3.1 2.8 5.3 0.0 3.6 5.5 0.0 0.1 35.8 43.2 0.0 5.6 0.5 5.1 8.5 16.9 8.4 4.8 0.5 8.4 0.2 3.4 41.8 16.7 9.5 2.2 7.9 5.5 4.5 0.0 0.8 20.7 4.1 16.2 5.4 0.5 0.9 14.2 0.0 26.2 17.8 0.2 39.1 1.5 4.5 9.4 14.1 0.4 14.7 2.3 3.0 0.9 2.5 1.3 0.0 3.7 6.4 0.1 0.1 3.3 9.9 0.1 42.2 7.8 15.9 3.5 NLRP8 "CLR19.2, NALP8, NOD16, PAN4" ENSG00000179709 "NLR family pyrin domain containing 8" Q86W28 19 55947832-55988629 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056989 Uncertain NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056989: AB_2683301" "unprognostic (2.43e-2)" "unprognostic (3.35e-1)" "unprognostic (3.13e-1)" "unprognostic (6.96e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NPAS4 "bHLHe79, Le-PAS, NXF, PASD10" ENSG00000174576 "Neuronal PAS domain protein 4" Q8IUM7 11 66421004-66426707 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 170.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 10.2;Horizontal cells: 11.8;Rod photoreceptor cells: 5.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "cerebellum: 170.4;cerebral cortex: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 4.9;cerebellum: 5.0;cerebral cortex: 7.5;hippocampal formation: 4.6;olfactory bulb: 3.8" HPA039255 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA039255: AB_10674282" "unprognostic (7.81e-2)" "unprognostic (9.93e-2)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.78e-3)" "unprognostic (4.97e-1)" "unprognostic (7.84e-2)" "unprognostic (1.85e-2)" "unprognostic (3.29e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-1)" "unprognostic (4.24e-1)" "unprognostic (3.21e-2)" 0.2 0.2 0.8 0.4 2.9 0.0 0.1 170.4 55.3 0.8 0.5 2.7 0.1 3.3 0.1 0.3 1.3 0.1 0.2 4.2 8.6 0.1 0.1 0.1 0.0 2.2 1.6 0.3 0.3 0.0 19.3 0.0 3.6 1.2 0.1 0.1 0.1 0.7 0.0 0.1 0.5 1.3 0.1 0.0 1.1 0.1 1.2 0.0 0.1 0.2 0.0 1.1 0.5 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 170.4 55.3 4.2 8.6 2.2 1.6 3.6 0.1 1.2 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.2 0.1 0.4 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.8 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 397.0;Endothelial cells: 307.2;Enteroendocrine cells: 281.6;Hepatic stellate cells: 406.2;Intestinal goblet cells: 589.1" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.0;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.0" "Cell line enhanced" "Detected in many" "MCF7: 138.4;RPMI-8226: 132.8;T-47d: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" 129.5 45.7 140.8 12.2 128.1 3.4 133.0 110.6 181.3 130.5 55.0 93.1 23.4 121.6 4.3 53.7 148.6 24.9 149.1 143.3 143.1 75.9 23.7 115.4 13.0 138.9 142.3 68.2 81.2 23.0 266.0 21.1 131.3 260.5 13.4 9.2 137.4 35.1 34.0 56.4 72.1 16.9 120.7 145.2 126.2 35.3 142.9 2.9 68.4 12.4 3.9 97.9 90.5 114.7 33.6 41.9 10.1 67.1 23.7 23.8 2.8 68.7 23.0 16.9 6.7 17.1 18.5 30.3 50.7 28.6 4.6 122.4 8.6 20.5 1.6 25.0 40.4 13.6 123.7 12.9 33.3 11.9 0.3 16.5 31.9 8.7 17.9 43.1 43.6 13.2 0.7 0.8 3.5 138.4 1.0 1.1 21.1 111.0 68.1 19.9 0.0 132.8 28.6 22.7 77.2 50.0 18.4 65.3 46.5 3.6 140.1 17.9 73.9 12.4 21.6 84.1 21.0 0.1 0.4 1.4 17.7 1.2 10.5 0.0 0.6 0.9 12.3 0.1 14.7 0.1 19.0 18.9 1.1 0.0 0.5 3.1 0.0 0.2 0.1 3.4 15.9 3.3 140.8 128.1 110.6 181.3 143.3 143.1 138.9 142.3 131.3 120.7 142.9 114.7 397.0 0.0 7.7 64.3 3.4 23.6 77.6 15.0 31.3 97.5 174.0 139.7 18.3 71.4 19.8 29.5 16.7 1.1 5.5 122.2 0.0 52.5 1.8 39.0 27.7 307.2 281.6 19.3 71.7 66.0 1.3 61.2 153.9 101.3 0.0 9.2 406.2 1.9 22.2 62.2 64.7 589.1 18.3 21.0 20.0 6.9 161.2 6.6 30.2 37.5 3.0 38.5 1.0 38.2 39.0 33.0 106.0 145.6 1.4 234.9 37.5 0.7 7.5 62.0 39.5 23.9 38.9 2.8 19.0 15.9 23.7 1.8 12.3 9.1 98.1 103.1 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" 84.6 95.7 81.4 75.9 104.4 32.7 82.6 52.1 176.7 112.4 72.4 133.0 134.9 180.7 150.9 133.9 135.0 97.2 196.4 122.6 65.6 126.5 74.0 110.5 48.7 42.9 42.2 79.1 96.6 167.2 47.1 123.1 39.8 170.8 142.0 135.5 101.0 204.4 51.2 68.1 124.9 298.4 28.5 71.8 96.4 69.2 60.4 42.6 112.4 70.1 69.4 140.6 84.9 87.9 101.9 179.1 100.9 74.5 201.6 180.7 141.1 229.1 373.5 258.3 228.4 122.4 317.7 58.7 133.0 331.2 319.2 411.1 164.4 191.3 147.6 105.6 109.3 46.7 83.3 110.2 143.1 72.6 124.9 149.1 165.2 167.4 100.7 254.8 139.5 52.0 26.7 65.2 187.2 81.2 32.4 45.3 93.5 127.3 63.3 52.1 115.8 49.9 353.7 148.3 61.6 19.2 222.4 122.4 151.3 249.6 110.9 97.7 159.0 199.7 133.8 116.0 135.8 56.5 113.8 51.4 185.8 111.0 140.0 5.9 13.5 13.8 6.4 18.5 5.2 3.8 3.6 5.9 5.3 2.9 3.6 4.2 28.0 3.9 14.8 5.5 4.3 13.6 81.4 104.4 52.1 176.7 122.6 65.6 42.9 42.2 39.8 28.5 60.4 87.9 67.1 76.9 66.0 72.1 18.3 65.0 27.0 43.3 51.2 93.0 50.5 45.7 106.9 48.6 60.6 82.8 50.1 7.0 28.8 133.8 1.9 18.1 3.7 73.4 46.7 44.6 103.0 7.4 216.6 24.0 9.2 64.5 41.3 92.1 28.4 33.9 50.0 43.1 25.0 38.7 162.7 90.9 42.7 77.4 46.6 9.9 15.2 61.8 42.7 86.2 43.4 41.2 12.3 63.8 67.4 41.4 66.7 38.4 20.2 26.9 52.3 20.7 92.1 49.7 19.7 35.5 74.0 11.7 10.8 61.9 54.6 6.8 23.9 35.3 52.6 30.7 NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adrenal gland: 122.6;brain: 423.9;prostate: 332.8" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 56.7;Prostatic glandular cells: 100.6" "Cancer enriched" "Detected in many" 187 "prostate cancer: 1214.9" "Region enriched" "Detected in all" 7 "hypothalamus: 423.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 34 "SH-SY5Y: 700.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 30700000 21000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "CAB016733: , CAB034368: AB_2298657, HPA036636: , HPA044572: AB_2678996, HPA056798: AB_2630371" "unprognostic (2.00e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (4.15e-1)" "unprognostic (3.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "unprognostic (6.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" 1.8 122.6 32.8 12.8 59.0 5.6 2.2 11.0 39.1 1.3 11.3 2.9 9.7 0.3 0.3 2.3 0.5 1.1 0.8 31.7 423.9 0.5 0.2 0.3 0.0 24.2 25.1 0.5 8.8 0.1 4.7 0.0 15.2 332.8 1.9 4.4 0.3 3.9 0.2 0.2 13.1 1.2 18.8 0.0 8.8 1.1 29.2 0.2 0.9 0.2 0.0 1.4 23.8 33.1 0.0 0.0 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.5 1.4 2.0 0.0 0.2 20.5 0.0 0.6 0.0 0.0 0.8 700.2 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 59.0 11.0 39.1 31.7 423.9 24.2 25.1 15.2 18.8 29.2 33.1 0.0 0.0 0.0 2.0 0.5 0.1 1.3 0.0 0.0 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 13.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 56.7 0.0 0.0 0.0 0.0 16.1 0.3 0.7 1.8 1.0 0.0 0.8 0.0 2.0 1.9 0.3 0.0 0.4 0.0 100.6 0.0 0.0 0.0 0.7 0.0 15.6 0.3 2.4 2.8 0.0 0.0 5.1 0.3 0.0 0.0 2.0 NPY4R "PP1, PPYR1, Y4" ENSG00000204174 "Neuropeptide Y receptor Y4" P50391 10 46461099-46465958 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.3;intestine: 6.0;skin 1: 3.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Region enhanced" "Detected in single" "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "A549: 28.6" HPA027863 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "HPA027863: AB_10602819" "unprognostic (2.26e-6)" "unprognostic (2.94e-1)" "unprognostic (8.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-3)" "unprognostic (1.98e-1)" "unprognostic (2.64e-3)" "unprognostic (6.58e-2)" "unprognostic (9.79e-2)" 0.5 0.0 0.3 0.7 0.1 0.0 0.2 0.6 0.2 0.1 0.0 4.9 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.7 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.6 1.3 6.0 0.0 0.0 0.0 0.0 3.0 1.2 1.0 0.3 0.0 1.9 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 28.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 5.9 0.0 0.4 0.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.2 0.2 0.4 0.5 0.5 0.6 0.3 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NRGN RC3 ENSG00000154146 Neurogranin Q92686 11 124739942-124747210 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "brain: 1158.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 245.6;Macrophages: 214.7;Smooth muscle cells: 60.5" "Cancer enhanced" "Detected in all" "glioma: 39.8" "Region enhanced" "Detected in many" "cerebral cortex: 1158.0" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "dendritic cells: 1.8;granulocytes: 2.5;monocytes: 3.6" "Cell line enhanced" "Detected in many" "HEL: 154.7;PC-3: 122.8" "Group enriched" "Detected in all" 9 "amygdala: 785.5;basal ganglia: 687.3;cerebral cortex: 1219.9;hippocampal formation: 641.9;white matter: 422.3" "Group enriched" "Detected in all" 6 "basal ganglia: 2940.0;cerebral cortex: 4703.6;hippocampal formation: 2490.2" "CAB006908, HPA038171" Enhanced NA NA 5300000 "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB006908: , HPA038171: AB_2675878" "unprognostic (1.37e-1)" "unprognostic (8.24e-3)" "unprognostic (3.95e-2)" "unprognostic (1.45e-2)" "unprognostic (3.49e-2)" "unprognostic (5.33e-3)" "unprognostic (1.02e-2)" "unprognostic (9.16e-2)" "unprognostic (2.87e-2)" "unprognostic (3.72e-3)" "unprognostic (4.14e-3)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.52e-5)" "unprognostic (8.29e-2)" "unprognostic (2.12e-1)" "unprognostic (4.06e-2)" "unprognostic (4.03e-2)" 13.8 4.4 119.9 7.8 563.0 36.3 9.1 0.0 1158.0 9.6 0.0 6.1 1.9 10.5 2.7 4.4 12.4 5.2 19.7 282.2 0.0 29.6 6.5 55.2 3.5 0.0 0.0 9.5 2.7 0.4 11.6 5.8 0.0 6.3 1.5 1.1 3.4 2.5 3.7 4.1 6.3 4.9 0.0 55.8 4.8 7.0 0.0 1.5 11.8 4.3 1.6 8.0 7.8 627.0 13.5 11.2 44.8 51.2 0.6 0.2 1.5 6.4 3.8 5.7 3.5 7.7 20.3 38.1 22.4 1.4 14.5 4.2 8.8 15.4 2.4 6.4 24.9 154.7 4.9 4.5 0.2 3.8 47.4 0.3 0.0 4.7 1.1 4.4 29.4 13.2 8.7 15.0 4.7 51.3 0.2 2.1 16.1 7.7 122.8 21.6 21.5 3.6 3.2 9.0 8.2 16.3 8.6 27.8 1.8 8.7 25.7 41.3 31.2 21.8 16.0 9.1 16.8 3.6 0.6 0.3 15.2 39.9 27.5 1.7 3.6 0.9 0.1 2.1 0.2 0.2 0.2 0.0 1.8 0.4 0.2 0.2 2.5 0.1 1.3 0.5 0.0 6.8 119.9 563.0 0.0 1158.0 282.2 0.0 0.0 0.0 0.0 0.0 0.0 627.0 12.5 0.0 41.9 35.9 4.3 3.6 0.9 0.6 0.6 5.3 2.1 2.7 2.3 1.5 0.1 0.0 0.0 1.6 4.7 2.2 3.9 0.9 3.1 1.7 1.4 20.8 6.0 5.5 245.6 0.2 2.7 3.8 1.5 1.5 1.3 0.9 15.7 1.0 13.0 0.0 14.4 1.7 0.0 43.4 15.2 7.2 0.6 214.7 5.4 42.2 45.4 0.1 25.7 29.7 33.4 0.3 0.3 0.7 3.4 0.6 0.3 0.1 0.2 1.8 19.7 1.6 60.5 3.6 6.5 1.3 1.4 0.1 4.6 0.8 2.2 1.6 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NT5DC1 "dJ486I3.1, MGC24302, NT5C2L1" ENSG00000178425 "5'-nucleotidase domain containing 1" Q5TFE4 6 116100851-116249497 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 117.6" "Cell type enriched" "Detected in all" 4 "Oligodendrocytes: 429.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030352, HPA079264" Uncertain Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 37: B-cells - Transcription" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA030352: AB_2154066, HPA079264: " "unprognostic (1.30e-1)" "unprognostic (2.92e-1)" "prognostic favorable (2.61e-4)" "unprognostic (1.14e-1)" "unprognostic (3.13e-2)" "unprognostic (7.80e-2)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (2.31e-2)" "unprognostic (4.61e-1)" "unprognostic (1.47e-1)" "prognostic favorable (7.49e-7)" "unprognostic (1.41e-1)" "unprognostic (8.53e-2)" "unprognostic (2.79e-1)" "unprognostic (9.63e-2)" 19.5 24.0 11.4 12.7 24.6 10.0 19.2 22.7 15.0 10.4 117.6 19.8 29.5 9.1 22.4 16.5 20.6 15.7 25.9 11.0 16.3 28.2 42.6 16.7 21.4 24.1 20.9 13.2 22.2 23.8 9.6 8.3 24.1 28.3 19.9 11.2 22.7 16.6 21.5 10.7 26.8 11.3 21.0 13.5 21.6 10.6 19.3 14.5 28.3 23.2 22.4 15.8 9.4 40.9 24.7 20.3 17.7 23.7 19.2 11.6 31.0 17.7 40.3 27.4 32.2 29.4 24.8 50.3 37.4 15.9 29.7 38.7 12.1 28.1 23.8 78.4 26.7 21.0 16.7 31.0 20.9 46.8 1.9 21.7 22.2 17.6 15.0 59.2 24.7 30.0 26.6 27.5 34.8 25.3 9.0 16.3 16.2 54.1 27.0 52.3 48.3 27.2 25.5 29.2 11.8 17.6 37.9 28.7 26.5 19.4 26.6 9.3 21.6 12.3 20.8 23.7 35.6 40.2 59.2 39.8 29.3 31.0 22.4 14.5 18.2 33.2 20.2 10.5 31.4 41.3 29.8 25.4 24.6 30.1 28.2 24.3 12.9 23.1 12.7 12.4 32.4 19.7 11.4 24.6 22.7 15.0 11.0 16.3 24.1 20.9 24.1 21.0 19.3 40.9 15.4 64.1 45.7 62.3 37.9 26.1 37.9 66.5 29.6 14.0 30.3 23.6 44.2 25.8 44.5 18.4 27.1 41.6 24.9 19.1 64.6 39.6 19.8 32.9 10.7 21.7 26.5 16.2 96.1 40.8 30.4 14.0 26.5 19.0 23.5 16.2 33.5 49.3 31.8 45.4 70.1 30.6 30.5 29.2 14.2 8.3 19.0 18.5 19.6 54.4 49.6 19.8 10.3 29.7 429.4 28.8 19.6 20.7 25.3 28.0 54.6 57.4 76.7 20.2 32.9 29.2 23.9 17.2 28.5 27.4 21.5 25.6 23.8 18.3 35.9 31.5 NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 80.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.2;Excitatory neurons: 36.6;Oligodendrocyte precursor cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol "Secreted - unknown location" NA NA "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Mitochondria Cytosol "HPA041634: AB_10795597" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (2.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.57e-1)" "unprognostic (2.19e-1)" "unprognostic (2.45e-2)" "unprognostic (5.43e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.60e-3)" "unprognostic (7.42e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.11e-4)" 2.9 4.0 14.2 1.9 12.0 17.5 3.3 0.0 13.3 9.3 0.0 80.5 1.0 23.1 5.0 5.2 3.7 1.4 1.9 23.3 7.8 2.0 5.0 2.8 1.3 1.5 1.8 2.9 3.5 0.8 4.5 1.5 1.4 7.5 7.7 2.3 4.1 5.4 7.8 2.5 4.7 6.8 1.2 1.6 6.6 3.1 8.9 0.6 1.9 3.3 1.2 21.7 5.7 4.8 3.6 6.5 3.6 4.2 5.1 4.0 6.8 5.9 3.5 4.1 2.6 4.4 0.9 6.1 1.1 7.0 4.5 4.1 5.2 11.7 5.9 4.5 4.2 7.6 2.5 5.2 2.8 4.1 1.9 3.5 2.5 5.3 22.7 8.3 2.4 3.0 12.2 3.0 9.2 3.3 3.6 6.6 4.5 5.2 6.9 4.9 6.3 2.3 6.5 2.4 4.9 2.0 4.9 5.4 7.1 3.3 3.1 3.8 3.2 4.0 4.8 5.5 11.9 2.7 3.5 4.4 3.8 6.2 6.0 0.4 0.5 0.0 0.6 0.6 1.2 1.3 0.9 0.5 1.5 1.4 0.7 0.6 0.9 0.6 0.4 1.9 0.2 0.3 14.2 12.0 0.0 13.3 23.3 7.8 1.5 1.8 1.4 1.2 8.9 4.8 1.4 0.0 2.3 3.9 2.7 4.5 21.9 3.0 21.6 2.0 5.6 7.4 3.8 2.8 2.1 1.8 0.0 5.2 2.7 5.8 0.0 2.1 12.1 14.0 11.9 1.7 41.2 1.3 36.6 2.0 4.7 3.8 7.7 19.4 0.0 3.7 0.7 5.3 1.8 10.1 24.4 11.4 10.2 4.1 6.5 10.5 5.0 2.8 0.0 6.5 2.9 0.8 1.0 29.1 2.7 2.7 2.2 8.2 2.7 13.0 1.1 2.1 6.9 5.0 0.0 5.6 5.7 0.4 3.1 9.0 4.4 4.1 2.5 4.1 9.2 9.8 NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 35.6;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 15.4;Breast myoepithelial cells: 24.3;Club cells: 9.5;Cytotrophoblasts: 13.6;Urothelial cells: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 31.1;HBEC3-KT: 11.7;hTCEpi: 50.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 4.3 0.7 0.0 0.0 0.1 3.7 10.8 2.5 0.0 1.0 0.1 0.0 0.1 0.0 3.5 0.0 0.1 0.2 0.2 0.0 0.0 1.6 3.2 0.1 20.1 0.0 0.0 8.2 7.1 17.1 31.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.9 1.5 2.5 1.1 6.5 9.6 0.1 3.9 0.2 0.3 2.1 0.0 0.0 9.3 0.0 0.0 0.1 0.0 3.4 13.8 0.0 3.5 0.0 0.5 31.1 0.1 11.7 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 50.4 0.0 1.6 3.1 0.0 0.1 0.0 0.2 0.4 1.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 8.8 0.0 0.1 0.7 0.1 0.0 4.3 8.0 0.1 0.2 1.8 3.5 0.2 9.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 7.0 35.6 24.0 15.4 0.0 3.4 24.3 0.4 0.0 9.5 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 5.7 0.0 0.0 0.0 0.9 0.0 1.3 1.7 3.1 2.7 0.3 0.1 0.0 11.9 NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 198.6;Hepatic stellate cells: 369.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 513.8;hTERT-HME1: 205.8;PC-3: 189.6;TIME: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" 24.4 17.3 6.4 5.7 7.5 0.1 72.9 4.4 10.5 26.5 12.0 16.5 12.0 12.7 15.3 15.6 34.4 22.4 66.8 8.9 5.7 107.6 26.7 70.2 2.9 5.9 8.7 86.1 62.5 13.3 7.6 11.9 5.7 42.4 18.1 0.6 32.6 59.1 12.6 8.8 17.5 15.0 6.1 181.5 48.7 12.1 6.2 6.2 14.4 19.9 6.5 49.5 14.4 8.7 26.7 71.3 2.0 0.1 28.5 45.0 3.0 49.7 513.8 67.1 78.2 56.1 48.8 0.0 3.5 105.3 88.1 42.2 0.6 15.3 34.0 0.0 4.3 2.3 12.7 11.1 1.7 0.0 0.1 1.1 43.5 75.0 205.8 72.9 133.3 0.4 0.0 0.1 25.4 20.0 0.2 0.3 1.1 7.9 189.6 0.2 0.6 0.1 64.8 133.4 0.3 0.6 60.5 77.1 1.3 2.3 22.2 0.1 289.3 25.9 9.5 101.3 5.2 0.1 0.1 0.0 5.9 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.5 4.4 10.5 8.9 5.7 5.9 8.7 5.7 6.1 6.2 8.7 31.9 41.7 123.2 6.2 3.8 4.7 120.5 15.2 39.3 1.8 77.6 55.4 44.8 44.3 30.8 198.6 0.0 6.2 1.3 4.4 5.9 36.7 10.3 36.4 3.2 35.5 0.0 2.7 28.1 28.0 3.6 33.7 23.0 28.1 1.3 25.9 369.5 10.2 0.4 0.0 70.6 37.2 4.1 26.3 3.7 3.8 2.1 2.6 7.2 20.6 0.6 0.3 0.0 112.6 1.8 36.7 4.0 3.4 0.9 108.9 1.5 84.3 38.0 0.2 26.3 119.0 73.9 1.9 0.6 5.9 2.3 1.6 3.3 1.4 6.4 127.0 NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132161676-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 40.4;brain: 74.6;retina: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Bipolar cells: 69.6;Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 108.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "basal ganglia: 74.6" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "HL-60: 6.8;HMC-1: 16.2;NB-4: 39.0;U-937: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071290 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA071290: AB_2686381" "unprognostic (5.01e-2)" "unprognostic (2.95e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.73e-2)" "unprognostic (2.87e-1)" "unprognostic (4.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-2)" "prognostic favorable (6.06e-4)" "unprognostic (9.30e-12)" "unprognostic (1.66e-1)" "unprognostic (3.23e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" 0.6 1.9 18.6 1.1 74.6 40.4 0.2 13.3 25.6 0.8 0.0 0.5 1.2 0.5 0.3 0.3 0.5 0.8 5.5 17.6 6.5 0.7 0.3 2.9 1.4 11.5 5.4 0.2 1.0 4.4 1.7 0.5 14.7 6.2 0.2 26.7 0.8 1.1 0.4 0.4 0.8 0.3 5.0 3.9 0.6 2.1 11.4 0.5 0.4 1.4 0.4 0.8 0.6 11.5 0.0 0.5 0.2 0.6 0.6 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.2 0.0 0.0 1.1 0.2 0.1 0.1 0.0 0.9 6.8 16.2 0.1 0.0 0.2 0.1 1.4 0.0 1.3 0.0 0.0 0.5 0.2 0.3 39.0 1.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 4.6 4.2 0.2 0.0 0.1 0.0 0.0 0.6 0.1 0.9 2.8 3.6 0.1 0.1 0.0 0.0 1.3 10.0 1.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 18.6 74.6 13.3 25.6 17.6 6.5 11.5 5.4 14.7 5.0 11.4 11.5 0.8 0.0 0.6 34.9 0.5 0.3 0.6 0.0 0.6 69.6 0.1 1.0 3.0 0.0 0.6 0.0 171.0 0.1 5.0 0.0 0.0 0.3 1.4 0.6 2.4 1.3 0.0 0.4 8.1 0.0 0.0 1.9 0.0 1.1 1.3 0.9 0.7 0.1 0.7 1.7 3.6 0.2 0.0 0.3 0.3 1.3 0.6 1.2 1.8 8.4 0.9 20.3 3.1 11.1 21.5 0.1 0.0 1.2 2.0 2.3 0.0 0.1 0.0 108.3 6.6 2.4 1.8 0.5 0.2 0.2 0.3 0.1 1.2 4.3 0.1 0.3 NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693694-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA044186: AB_10968571, HPA063605: AB_2685058" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (3.14e-1)" "prognostic favorable (2.79e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (6.12e-3)" "unprognostic (6.81e-2)" "prognostic favorable (1.02e-6)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (6.81e-3)" 19.7 46.4 43.1 12.0 44.8 22.2 21.5 43.6 52.5 23.1 45.6 28.5 21.7 21.4 15.3 28.9 23.4 8.4 58.2 44.1 42.0 43.4 64.1 17.2 17.9 45.3 43.2 22.7 24.6 20.4 39.9 8.0 41.9 34.8 11.9 14.5 26.6 14.7 25.0 25.2 29.2 8.5 43.3 33.7 30.1 22.8 44.3 18.2 30.8 16.9 13.1 22.7 21.8 45.7 14.7 23.8 21.2 28.7 15.7 12.1 19.4 17.2 12.9 20.4 12.8 26.9 11.6 15.2 24.4 20.7 10.3 16.8 23.1 23.4 9.5 22.6 38.9 16.8 21.1 32.8 17.0 24.4 19.2 18.7 21.3 17.2 10.7 13.9 15.1 22.6 31.2 18.5 20.1 57.3 36.8 36.0 33.6 24.4 27.0 50.9 22.4 24.2 24.8 18.0 41.8 31.5 25.1 25.9 11.7 16.5 38.4 56.4 20.0 16.7 25.3 39.8 15.9 32.1 20.5 26.1 10.4 32.3 34.8 56.6 54.3 96.2 52.6 48.2 63.1 60.7 63.4 62.8 50.2 65.3 74.0 63.5 68.2 63.9 53.5 83.6 78.3 98.1 43.1 44.8 43.6 52.5 44.1 42.0 45.3 43.2 41.9 43.3 44.3 45.7 23.3 16.0 22.4 14.4 32.6 14.0 19.7 37.4 27.9 52.1 36.0 36.2 52.6 24.3 28.0 42.3 10.4 53.8 43.6 47.7 109.5 28.7 5.2 28.7 33.6 21.4 43.1 23.1 10.2 30.9 31.8 24.0 30.5 29.0 27.9 31.7 17.9 41.8 40.9 47.1 11.8 51.7 89.5 18.3 18.7 8.7 31.4 20.8 30.2 3.7 43.3 83.5 34.0 9.5 15.0 30.0 48.5 50.0 33.0 17.9 77.8 98.2 20.1 58.3 46.0 14.2 22.8 14.8 34.7 24.9 16.6 49.1 43.6 58.0 51.4 17.6 NUPR2 NUPR1L ENSG00000185290 "Nuclear protein 2, transcriptional regulator" A6NF83 7 56114681-56116417 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "testis: 354.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 15101.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 13.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 5.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 5.1" "Cell line enhanced" "Detected in many" "RPMI-8226: 11.9" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (9.52e-2)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (1.50e-2)" "prognostic favorable (9.53e-5)" "unprognostic (1.66e-1)" "unprognostic (8.44e-2)" "unprognostic (2.74e-1)" "unprognostic (5.44e-2)" 2.2 3.3 7.3 0.3 7.4 1.0 2.6 8.4 9.2 1.8 5.3 0.9 1.2 0.7 3.0 0.7 1.6 0.4 1.2 7.3 8.1 18.2 2.3 1.0 0.6 6.6 6.7 1.3 4.0 3.3 12.7 0.7 7.1 6.5 0.7 2.6 7.7 5.7 1.5 1.4 0.7 0.6 6.5 0.7 6.0 354.9 8.7 1.3 15.4 1.0 0.6 0.6 0.8 6.5 1.0 3.1 1.4 4.0 3.6 1.5 0.5 0.2 1.4 0.7 0.4 0.4 2.2 0.4 4.7 0.1 1.5 0.3 1.9 0.5 0.9 0.7 6.0 2.4 1.4 2.7 1.9 0.8 0.3 2.8 2.0 1.0 4.4 1.7 1.3 3.1 3.0 2.5 1.4 3.3 1.3 3.1 1.3 1.2 3.3 1.1 1.6 11.9 2.3 0.5 3.9 3.6 1.9 0.5 5.4 4.6 1.2 0.7 1.0 0.6 1.7 0.9 0.7 3.8 4.8 4.6 2.4 3.0 1.1 2.0 0.3 0.6 0.3 0.0 0.5 0.4 1.8 0.5 0.4 0.5 5.1 1.4 0.1 0.4 0.5 0.8 0.5 0.8 7.3 7.4 8.4 9.2 7.3 8.1 6.6 6.7 7.1 6.5 8.7 6.5 0.2 0.0 1.5 0.0 0.2 0.0 21.3 0.0 2.2 1.4 39.6 41.3 0.0 0.0 1.8 90.1 0.0 9.6 0.5 1.4 422.6 3.6 3765.4 3.9 0.1 6.7 14.6 0.0 0.0 1.8 1.7 0.9 9.7 2.4 1.3 0.1 0.0 0.0 0.6 16.8 0.0 3.0 0.0 0.0 0.0 15101.8 94.1 5.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.5 68.4 0.0 24.8 0.1 3.2 2.9 0.8 85.5 0.0 1.5 112.8 53.3 2.7 0.0 2.9 0.6 0.0 2.0 20.4 NWD1 ENSG00000188039 "NACHT and WD repeat domain containing 1" Q149M9 19 16719847-16817963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "choroid plexus: 192.4" "Group enriched" "Detected in some" 4 "Astrocytes: 41.4;Endometrial ciliated cells: 83.9;Respiratory ciliated cells: 92.0" "Cancer enriched" "Detected in many" 6 "prostate cancer: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075476 Approved Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Cytosol" "HPA075476: " "unprognostic (5.29e-3)" "unprognostic (3.08e-2)" "unprognostic (3.05e-2)" "prognostic favorable (2.55e-4)" "unprognostic (2.49e-1)" "unprognostic (4.20e-4)" "unprognostic (6.54e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.94e-2)" "unprognostic (1.76e-1)" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (5.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.25e-1)" 0.0 0.0 5.4 0.0 6.2 0.1 0.2 7.6 4.9 1.3 192.4 0.5 0.0 0.2 0.4 0.2 12.6 0.2 0.0 12.2 5.2 0.2 0.0 1.3 0.0 6.2 8.8 0.0 1.5 0.0 0.7 0.0 6.1 6.8 0.1 1.1 1.3 1.8 0.0 0.2 0.0 0.0 3.2 0.0 0.8 0.2 10.1 0.2 0.7 0.0 0.0 0.1 0.0 3.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.4 6.2 7.6 4.9 12.2 5.2 6.2 8.8 6.1 3.2 10.1 3.7 0.0 0.0 1.5 41.4 0.3 0.3 1.7 3.5 0.0 0.2 0.5 0.3 0.9 0.0 4.5 0.0 0.0 0.1 0.0 0.4 0.0 0.1 17.9 83.9 0.8 0.3 1.2 0.0 2.4 0.0 0.2 0.3 0.0 3.7 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.6 2.0 0.0 0.4 3.3 0.6 0.3 0.0 0.0 0.0 8.9 0.0 1.5 1.2 0.2 0.4 0.0 0.0 4.0 0.0 0.1 92.0 0.6 0.0 1.1 1.4 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.4 1.4 NXPH4 NPH4 ENSG00000182379 "Neurexophilin 4" O95158 12 57216794-57226449 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;skin 1: 19.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.5;Cytotrophoblasts: 29.0;Muller glia cells: 18.5;Suprabasal keratinocytes: 10.4;Syncytiotrophoblasts: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 76.8;RH-30: 62.3;RPMI-8226: 43.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in brain" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.08e-2)" "unprognostic (4.84e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (6.21e-4)" "prognostic unfavorable (5.42e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (3.07e-1)" "unprognostic (1.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (7.83e-2)" "unprognostic (2.73e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-3)" 2.5 0.6 6.3 0.3 4.1 0.4 0.7 8.3 3.6 2.3 0.6 0.1 0.0 0.0 0.2 3.0 0.1 0.0 2.7 8.3 13.8 0.7 0.8 0.3 0.5 13.3 7.1 0.0 1.5 1.7 0.3 2.7 18.4 4.4 0.0 5.0 4.0 0.0 0.2 19.4 0.2 0.1 7.5 0.4 0.1 1.2 7.1 0.1 0.4 0.0 0.3 0.1 2.8 5.0 18.1 1.4 0.4 76.8 8.6 2.2 7.1 4.9 11.5 2.1 2.7 5.0 0.9 19.4 7.6 5.1 3.2 16.2 10.3 2.4 0.6 3.4 20.6 0.1 0.6 0.3 7.4 0.7 2.5 2.0 4.0 2.0 3.2 2.5 0.0 1.2 0.8 20.0 1.5 18.6 0.0 0.0 0.7 0.4 13.5 1.0 62.3 43.1 0.0 3.2 12.3 0.7 11.0 22.5 23.2 0.2 22.4 0.6 0.0 5.4 17.8 2.3 5.8 10.8 2.3 6.9 3.5 9.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.1 8.3 3.6 8.3 13.8 13.3 7.1 18.4 7.5 7.1 5.0 0.8 0.0 0.0 0.7 8.0 14.5 0.4 1.1 3.4 4.7 0.7 0.9 0.8 0.0 0.7 0.0 8.4 29.0 0.3 0.1 0.0 0.8 0.0 0.1 0.4 0.5 7.2 0.0 0.7 0.0 1.9 1.1 0.5 0.1 0.0 1.1 0.0 0.1 2.0 1.7 1.4 0.0 2.0 0.0 0.8 0.0 0.0 0.4 3.6 0.0 0.0 18.5 0.0 0.0 0.1 0.6 0.0 0.4 0.3 3.3 0.0 0.0 1.0 0.5 0.0 2.4 3.6 0.7 4.5 1.8 10.4 29.3 0.4 0.0 0.0 0.4 OAZ3 ENSG00000143450 "Ornithine decarboxylase antizyme 3" Q9UMX2 1 151762899-151771334 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 244.7" "Cell type enriched" "Detected in many" 5 "Late spermatids: 12007.9" "Cancer enhanced" "Detected in many" "prostate cancer: 3.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030136, HPA045808" Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA030136: AB_2673331, HPA045808: " "unprognostic (2.12e-1)" "unprognostic (3.86e-1)" "unprognostic (1.53e-1)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.01e-2)" "unprognostic (1.48e-3)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (2.89e-1)" "unprognostic (8.05e-6)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (2.50e-2)" "unprognostic (8.36e-2)" 1.5 1.6 2.3 1.6 2.3 0.6 2.4 4.2 2.7 0.6 1.5 1.3 0.7 0.5 2.6 1.7 0.9 0.8 1.1 2.6 2.3 1.6 2.8 1.4 1.5 2.7 2.2 0.3 2.1 4.3 2.7 0.6 2.8 15.3 1.6 2.7 8.2 1.3 2.9 1.2 1.2 0.5 1.9 1.3 1.4 244.7 2.3 0.6 3.3 0.9 0.6 1.1 1.0 2.3 0.9 1.8 1.0 2.5 0.8 2.4 2.3 1.9 0.4 1.7 0.7 1.0 2.3 0.8 1.5 0.6 1.2 0.9 1.0 1.7 0.5 5.8 5.3 0.8 3.2 1.5 1.0 0.4 0.9 3.8 1.0 1.9 2.3 1.1 2.6 2.3 1.2 2.8 1.9 7.7 0.7 1.3 2.5 3.6 1.9 0.4 0.8 1.3 0.3 2.3 1.2 2.8 0.8 3.7 3.6 2.3 8.2 2.1 2.3 1.0 0.5 1.9 1.0 4.0 7.5 2.0 1.3 1.2 2.7 0.6 0.8 0.1 0.3 0.4 0.3 0.3 0.3 0.6 1.0 0.2 0.3 0.6 0.4 0.7 1.5 0.3 0.7 0.4 2.3 2.3 4.2 2.7 2.6 2.3 2.7 2.2 2.8 1.9 2.3 2.3 2.3 0.0 1.7 0.3 0.3 0.8 2.6 1.8 1.8 0.5 16.0 6.2 1.4 0.0 2.2 0.0 2.1 1.7 0.9 4.2 1.9 2.4 2386.5 3.4 0.6 5.3 3.6 0.4 0.4 3.1 3.0 1.0 1.5 1.5 1.3 0.5 1.8 3.1 4.8 0.0 0.3 7.4 2.0 4.2 1.6 12007.9 46.0 5.1 1.8 0.0 1.8 1.7 0.0 0.0 0.3 3.3 4.9 42.5 1.6 20.4 5.7 7.4 3.2 1.6 0.0 0.4 0.8 67.6 31.8 1.2 0.6 1.5 0.6 1.4 2.7 3.2 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 14.5" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 4.5;Excitatory neurons: 6.7;Extravillous trophoblasts: 8.0;Glandular and luminal cells: 9.8;Inhibitory neurons: 10.1;Leydig cells: 4.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.1 0.1 7.3 0.0 14.5 0.0 0.0 1.3 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 5.4 0.0 0.0 0.1 0.0 5.8 1.7 0.0 0.0 0.0 0.0 0.2 5.1 1.6 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 6.9 0.1 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 14.5 1.3 8.3 3.9 5.4 5.8 1.7 5.1 0.3 6.9 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 4.5 0.6 0.1 0.0 0.0 6.7 0.0 8.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 OR2C3 "OR2C4, OR2C5P, OST742" ENSG00000196242 "Olfactory receptor family 2 subfamily C member 3" Q8N628 1 247524677-247536440 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 2.4;granulocytes: 1.3;Late spermatids: 3.7;Spermatocytes: 2.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Immune cell enriched" "Detected in single" 5 "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA058578 Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA058578: AB_2683761" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.03e-1)" 0.0 0.1 0.2 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 1.3 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OR7A5 HTPCR2 ENSG00000188269 "Olfactory receptor family 7 subfamily A member 5" Q15622 19 14826241-14835185 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.9;epididymis: 4.5;parathyroid gland: 7.0" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.3" "Cancer enriched" "Detected in single" 8 "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053823 Uncertain NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA053823: AB_2682274" "unprognostic (3.26e-4)" "unprognostic (1.44e-1)" "unprognostic (7.46e-2)" "unprognostic (6.19e-3)" "unprognostic (4.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (6.78e-2)" "unprognostic (2.01e-7)" "unprognostic (6.45e-2)" "unprognostic (9.64e-2)" "unprognostic (6.44e-2)" "unprognostic (2.47e-3)" 0.0 0.1 0.8 0.0 2.7 0.0 0.7 2.7 2.0 0.1 0.4 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.9 1.5 0.0 0.0 0.0 0.0 3.0 1.8 0.0 0.0 7.0 1.3 0.0 3.3 0.5 0.0 0.0 0.2 0.6 0.0 0.7 0.0 0.0 0.9 0.0 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 2.7 2.0 0.9 1.5 3.0 1.8 3.3 0.9 2.5 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 OSBPL3 "KIAA0704, ORP-3, ORP3, OSBP3" ENSG00000070882 "Oxysterol binding protein like 3" Q9H4L5 7 24796540-24981634 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Excitatory neurons: 176.1;Inhibitory neurons: 272.2;Microglial cells: 94.6;Plasma cells: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000691, HPA048401" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoli "HPA000691: AB_1854814, HPA048401: AB_2680386" "unprognostic (3.57e-1)" "unprognostic (1.14e-1)" "unprognostic (6.11e-3)" "unprognostic (3.89e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.57e-3)" "unprognostic (4.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (2.34e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.06e-2)" 2.6 1.2 3.6 6.8 4.2 4.1 3.9 2.8 5.9 10.2 3.8 5.9 9.3 2.2 0.8 7.6 5.1 5.0 2.6 3.9 4.4 16.0 1.2 8.6 11.3 3.8 3.7 5.2 1.9 14.1 2.0 3.9 3.5 2.2 6.0 1.3 3.7 2.5 3.3 10.3 7.6 3.7 3.1 6.8 8.5 2.8 4.5 8.3 9.8 2.0 14.4 13.3 6.5 5.1 40.2 10.7 7.8 14.4 17.3 34.5 17.5 44.5 49.3 20.4 32.1 27.0 52.0 22.2 6.2 47.8 26.9 34.6 23.6 33.4 31.4 13.5 9.8 5.3 16.4 20.4 24.5 15.3 113.8 17.0 27.2 26.7 31.8 26.0 31.0 19.0 28.4 30.1 34.9 0.0 9.4 18.7 15.3 38.1 13.7 7.5 21.6 9.1 20.4 28.2 1.6 16.1 30.3 21.5 6.7 23.0 11.1 1.5 37.1 9.1 17.9 49.4 33.7 20.7 32.8 55.6 19.5 24.7 102.0 5.8 1.9 1.5 8.5 1.7 7.3 3.3 5.3 5.6 3.3 1.6 1.8 3.5 0.4 7.7 1.2 2.3 9.5 2.5 3.6 4.2 2.8 5.9 3.9 4.4 3.8 3.7 3.5 3.1 4.5 5.1 2.2 0.0 26.1 123.1 18.3 12.1 8.0 8.8 21.6 0.3 3.8 4.4 5.5 5.7 22.2 25.8 0.0 8.4 13.2 3.8 3.9 3.5 0.3 24.6 2.3 3.6 1.8 11.1 176.1 3.9 2.1 3.1 19.4 31.9 0.0 0.4 3.6 0.5 10.8 0.0 272.2 1.7 20.3 12.7 9.3 0.3 0.6 13.2 16.0 94.6 7.8 4.8 14.4 44.2 3.6 24.4 4.5 0.0 91.7 5.2 3.3 0.5 53.1 0.2 0.0 3.4 4.6 0.5 5.0 16.5 8.0 4.0 18.5 20.3 4.5 16.5 OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" 24.2 13.5 18.1 24.3 43.3 32.5 21.1 9.7 22.5 22.6 12.3 11.2 9.3 22.3 7.7 24.4 10.5 18.4 14.0 15.3 13.7 36.4 19.2 19.6 30.9 11.7 13.4 17.4 14.0 13.0 5.6 18.2 14.0 14.9 11.7 14.2 13.5 12.7 10.7 28.7 13.0 18.9 9.1 26.7 16.0 16.6 13.1 33.7 14.3 11.5 32.0 19.1 10.2 16.6 36.5 22.8 49.7 35.5 67.5 94.8 31.6 54.7 76.3 34.2 31.1 33.2 14.6 50.8 30.4 65.3 21.5 14.9 37.2 31.6 51.3 43.6 33.3 136.0 21.0 19.8 41.7 87.2 53.1 50.4 58.7 51.2 63.3 61.8 30.0 29.1 95.0 22.7 57.3 25.0 58.8 41.4 24.3 13.2 22.6 30.4 67.7 29.3 26.4 30.3 27.2 28.4 46.7 16.6 34.0 38.9 13.0 52.4 70.6 55.0 27.5 57.5 29.7 22.7 38.4 54.6 21.0 47.9 32.8 134.8 50.8 74.1 29.2 37.4 27.9 45.3 31.2 24.6 46.9 40.8 27.9 23.2 195.7 36.0 44.5 54.9 41.1 31.8 18.1 43.3 9.7 22.5 15.3 13.7 11.7 13.4 14.0 9.1 13.1 16.6 63.5 57.7 58.3 54.5 87.8 116.2 65.7 39.6 114.9 49.7 68.4 55.5 42.5 25.8 36.1 51.5 89.6 34.8 111.3 13.6 60.7 53.9 47.4 29.0 102.6 68.7 9.5 63.5 246.3 55.2 28.7 98.0 28.5 44.1 254.8 36.3 52.1 45.9 77.1 42.1 248.6 25.8 40.7 98.0 127.0 22.1 65.9 142.0 35.6 79.6 149.3 50.2 125.7 113.6 92.9 104.0 28.3 82.8 56.8 54.6 23.9 180.2 37.4 37.3 46.0 79.3 83.1 66.2 129.9 89.9 124.5 48.2 105.3 58.4 20.0 62.4 OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.5;testis: 2.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 14.3;Inhibitory neurons: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Daudi: 5.5" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" 0.2 0.2 0.7 0.3 1.2 0.1 0.2 0.0 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.9 0.5 0.1 0.2 4.5 0.1 0.0 0.6 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.6 0.1 2.4 0.7 0.0 1.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 1.2 0.9 0.5 0.0 0.6 0.1 0.1 0.7 0.5 0.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.7 0.0 0.0 14.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706421 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 189.0;retina: 92.2" "Group enriched" "Detected in some" 7 "Collecting duct cells: 7.3;Rod photoreceptor cells: 16.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "REH: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.59e-2)" "unprognostic (3.74e-1)" "unprognostic (8.03e-2)" "unprognostic (9.77e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.84e-2)" "unprognostic (3.06e-1)" "unprognostic (9.27e-2)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" 0.0 0.0 0.1 0.0 0.3 0.4 3.4 0.8 0.2 0.1 0.1 0.0 0.0 0.2 189.0 0.1 0.3 0.0 0.0 0.0 0.1 5.3 0.0 2.4 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 92.2 0.8 5.8 0.4 9.1 0.1 0.0 0.1 0.0 0.5 0.5 0.8 0.0 0.0 0.0 0.1 0.9 0.2 0.7 3.4 0.0 0.3 0.0 0.0 0.0 0.5 0.8 0.6 0.1 0.3 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.2 0.2 2.7 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.2 0.0 0.1 0.7 0.4 1.0 0.1 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.1 1.3 0.1 0.0 0.0 7.3 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.1 0.0 0.7 0.0 16.6 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 OVOL2 "bA504H3.3, CHED, CHED1, HOVO2, ZNF339" ENSG00000125850 "Ovo like zinc finger 2" Q9BRP0 20 17956979-18059188 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 7.1;stomach 1: 7.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 24.4;Spermatocytes: 37.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.6;CACO-2: 4.1;CAPAN-2: 7.3;HaCaT: 5.4;OE19: 10.0;SCLC-21H: 8.3;SK-BR-3: 5.4" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.9;hippocampal formation: 3.3" HPA038531 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA038531: AB_10673012" "unprognostic (2.85e-2)" "unprognostic (5.13e-2)" "unprognostic (2.41e-2)" "unprognostic (7.35e-2)" "unprognostic (2.14e-1)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (2.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-4)" "unprognostic (4.77e-3)" "unprognostic (2.92e-1)" "unprognostic (2.57e-2)" "unprognostic (3.76e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 2.8 0.0 0.1 1.5 0.0 3.5 2.9 0.3 0.5 5.3 1.0 0.3 0.0 0.0 0.0 1.1 0.0 1.5 0.0 0.0 0.0 0.0 4.5 0.4 1.2 0.1 0.0 4.1 1.3 0.0 7.1 0.7 0.0 6.7 2.3 0.0 0.0 0.0 7.9 1.4 0.0 0.1 3.3 0.0 0.2 1.2 3.7 0.0 5.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.1 7.3 0.0 1.0 0.0 0.3 5.4 1.0 1.3 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 10.0 0.1 0.0 0.0 2.1 0.1 2.6 8.3 0.0 0.0 5.4 0.0 0.1 2.8 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.4 8.4 0.3 0.1 8.3 11.4 4.8 4.0 0.0 14.6 11.7 1.4 8.6 8.8 1.8 0.0 1.7 0.2 17.1 0.0 8.4 18.6 24.4 1.3 0.3 3.6 0.0 3.3 10.9 3.2 0.2 17.9 18.4 0.0 0.0 0.0 0.0 0.1 1.7 1.7 15.5 10.2 0.0 0.7 7.4 0.3 0.5 0.0 0.0 0.0 0.7 0.0 1.0 0.3 16.9 10.5 0.4 0.0 12.9 12.0 1.6 6.4 0.0 0.0 0.0 0.7 37.9 0.7 4.9 9.8 0.1 0.4 0.0 12.3 15.1 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 OXNAD1 MGC15763 ENSG00000154814 "Oxidoreductase NAD binding domain containing 1" Q96HP4 3 16265160-16350299 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.0;Inhibitory neurons: 62.8;T-cells: 90.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 81.0" "Lineage enriched" "Detected in all" 4 "T-cells: 81.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036830, HPA059160" Approved Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA036830: AB_2675338, HPA059160: AB_2683936" "unprognostic (4.49e-2)" "unprognostic (7.41e-3)" "unprognostic (2.71e-3)" "unprognostic (2.38e-3)" "unprognostic (4.65e-2)" "unprognostic (3.23e-2)" "unprognostic (1.46e-1)" "unprognostic (2.31e-2)" "unprognostic (1.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.46e-1)" "unprognostic (8.08e-2)" "prognostic favorable (1.00e-7)" "unprognostic (2.22e-2)" "unprognostic (1.03e-1)" "unprognostic (6.95e-3)" "prognostic favorable (7.63e-4)" 5.8 4.0 2.0 11.4 3.3 8.9 4.8 2.4 3.7 2.7 3.7 8.5 12.2 3.0 2.5 5.4 3.4 5.0 9.0 1.8 2.4 8.7 16.9 4.2 17.0 2.3 2.4 3.0 3.7 7.3 2.4 3.6 2.5 2.9 7.2 4.6 4.4 2.6 14.9 4.1 14.1 2.8 1.3 7.1 7.3 4.4 2.8 18.1 5.6 10.1 12.1 5.4 3.3 3.4 8.3 12.0 7.6 12.0 8.8 7.8 29.7 8.8 6.5 11.8 9.5 17.2 8.2 11.8 5.4 5.5 6.5 5.9 15.9 14.3 11.2 21.6 10.5 17.4 9.6 9.3 9.1 28.3 10.2 5.8 10.5 19.2 9.2 3.7 9.3 12.0 24.1 27.3 5.2 14.7 16.6 14.8 16.3 12.4 13.8 14.6 9.3 20.7 8.0 9.9 5.4 7.5 9.8 16.3 14.0 8.2 10.4 16.1 4.2 7.7 9.8 8.5 14.4 9.9 19.0 19.0 9.1 24.3 10.5 0.1 3.8 3.1 22.6 5.4 30.3 5.5 34.6 24.5 6.0 4.3 81.0 61.8 3.4 19.3 5.4 4.6 20.4 19.3 2.0 3.3 2.4 3.7 1.8 2.4 2.3 2.4 2.5 1.3 2.8 3.4 4.9 0.0 8.6 35.6 8.9 2.4 5.4 7.9 6.2 5.8 5.7 3.4 12.8 7.2 4.7 7.3 6.2 10.2 29.4 8.9 31.3 9.8 40.2 3.9 5.5 4.4 3.0 16.2 67.0 6.2 8.1 5.1 11.2 3.9 20.8 5.8 3.9 23.3 8.5 3.3 62.8 7.6 6.1 5.2 3.6 31.7 3.1 6.3 5.4 17.8 10.2 5.8 41.2 36.2 42.1 7.5 2.9 1.9 20.8 5.0 21.2 15.7 7.2 11.7 6.6 6.1 6.8 9.0 11.7 7.5 3.4 5.1 90.0 7.8 11.5 6.5 P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.7;skeletal muscle: 50.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.5;Distal enterocytes: 18.0;Pancreatic endocrine cells: 18.9;Proximal enterocytes: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.6" "Group enriched" "Detected in many" 12 "granulocytes: 57.6;monocytes: 20.2" "Cell line enhanced" "Detected in many" "HaCaT: 32.8;HL-60: 30.8;MCF7: 25.1;NB-4: 26.1;PC-3: 24.5;SK-BR-3: 29.6;THP-1: 76.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" 0.8 3.8 1.4 1.8 1.6 15.8 1.7 1.3 1.0 6.9 1.1 3.3 2.7 0.5 0.3 29.7 1.4 0.7 10.0 1.3 1.8 2.7 3.9 3.5 0.1 2.1 1.9 0.4 0.7 4.8 1.6 2.0 1.6 2.1 2.8 1.2 6.2 1.2 50.2 6.0 5.9 0.5 1.3 3.9 1.1 1.2 2.6 0.2 8.8 31.3 2.8 2.2 19.0 1.4 7.2 6.7 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 17.2 5.4 0.0 10.4 0.4 0.0 32.8 0.9 15.2 0.0 0.0 0.6 2.3 0.6 3.2 0.1 30.8 0.0 0.0 6.8 2.3 0.5 0.0 1.4 0.0 1.4 0.0 0.0 25.1 0.1 26.1 0.4 6.8 24.5 0.0 0.0 1.1 2.4 17.9 0.0 0.0 0.5 29.6 0.0 0.2 12.9 76.5 10.2 0.0 0.3 0.0 0.0 1.0 0.4 0.0 0.0 5.6 0.0 0.5 6.6 57.6 0.0 20.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.0 13.5 0.0 0.0 2.5 1.4 1.6 1.3 1.0 1.3 1.8 2.1 1.9 1.6 1.3 2.6 1.4 0.7 3.2 0.5 0.0 0.2 3.7 8.6 13.2 1.2 0.7 2.8 0.5 6.1 5.7 10.3 0.0 0.0 16.5 0.0 18.0 1.9 5.8 6.0 1.4 0.1 1.5 0.0 0.8 0.0 6.3 1.3 0.7 0.5 0.8 0.0 1.2 0.0 5.2 2.6 0.0 0.0 5.1 0.0 3.7 0.7 8.8 0.0 4.5 0.0 0.0 2.8 6.0 0.0 0.0 0.1 18.9 10.9 0.0 0.2 5.3 14.2 0.3 2.8 0.4 0.0 0.8 1.4 0.1 0.1 12.6 7.2 10.9 0.1 0.1 3.0 11.7 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cell line enhanced" "Detected in many" "GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 4.9 41.6 2.8 4.9 3.1 1.0 6.5 3.0 3.1 17.0 1.8 24.0 2.7 17.6 18.5 11.0 8.0 4.8 8.8 3.3 4.8 51.3 7.0 28.7 2.4 7.6 4.7 16.1 3.6 2.3 8.2 9.2 6.7 37.6 10.4 19.3 4.9 26.5 1.2 17.8 6.7 32.4 5.2 54.8 23.9 4.2 4.9 5.2 3.0 1.7 2.0 11.9 19.9 8.3 46.9 18.2 35.1 0.2 0.6 1.4 42.1 48.7 19.3 7.8 12.6 15.0 18.0 0.1 27.1 8.6 120.2 109.9 0.1 65.3 16.3 0.4 6.2 0.1 12.1 0.3 35.4 0.2 0.3 16.9 21.4 15.2 5.4 73.5 1.4 0.1 0.1 0.4 12.3 1.1 0.1 0.4 11.0 31.3 3.7 0.1 7.1 2.8 109.8 77.5 2.5 0.3 66.1 3.7 29.3 51.1 0.1 0.7 24.4 45.9 16.8 0.4 8.9 3.4 0.2 0.5 10.6 0.2 60.2 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.1 0.0 28.9 0.0 0.2 2.8 3.1 3.0 3.1 3.3 4.8 7.6 4.7 6.7 5.2 4.9 8.3 5.7 48.1 80.3 19.2 1.0 0.0 7.7 0.0 13.6 2.3 1.6 9.9 1.0 2.8 3.1 44.1 4.2 42.0 9.5 19.8 5.9 4.7 19.6 2.0 27.3 10.5 0.0 2.7 55.6 0.8 14.7 10.3 8.6 1.5 1.3 124.1 32.5 0.8 11.4 10.1 60.4 0.5 0.0 3.2 0.0 14.9 4.7 5.6 0.0 91.8 0.8 44.5 0.0 43.7 4.4 30.6 1.9 0.0 0.2 15.1 0.0 26.2 0.0 1.2 0.0 10.9 45.2 0.5 0.9 13.5 0.0 38.6 0.7 74.3 2.1 3.9 PABPC1L2A RBM32A ENSG00000186288 "Poly(A) binding protein cytoplasmic 1 like 2A" Q5JQF8 X 73077276-73079512 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;prostate: 2.5" "Group enriched" "Detected in some" 10 "Early spermatids: 14.3;Late spermatids: 48.5" "Cancer enriched" "Detected in single" 15 "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.5" HPA041573 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "HPA041573: AB_2677556" "unprognostic (4.30e-2)" "unprognostic (2.19e-1)" "unprognostic (3.22e-1)" 0.0 1.0 4.6 0.0 3.9 0.0 0.0 2.3 6.3 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 3.7 6.1 0.0 0.0 0.0 0.0 2.6 2.7 0.0 0.0 0.1 2.0 0.0 2.5 2.5 0.0 1.1 1.8 0.2 0.0 0.0 0.1 0.0 0.8 0.2 0.0 1.7 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.9 2.3 6.3 3.7 6.1 2.6 2.7 2.5 0.8 4.3 3.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 48.5 0.3 0.0 0.0 0.0 0.0 0.5 0.0 3.0 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PABPC1L2B RBM32B ENSG00000184388 "Poly(A) binding protein cytoplasmic 1 like 2B" Q5JQF8 X 73002939-73006106 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.2;pituitary gland: 2.1;prostate: 2.7;salivary gland: 2.1;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Excitatory neurons: 2.2;Inhibitory neurons: 2.7;Oligodendrocytes: 1.7" "Cancer enriched" "Detected in single" 23 "prostate cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" HPA041573 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA041573: AB_2677556" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (3.31e-1)" 0.0 0.6 2.6 0.0 1.7 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.3 3.4 0.0 0.0 0.0 0.0 1.6 1.0 0.0 0.0 0.0 2.1 0.0 0.8 2.7 0.0 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 0.2 5.2 1.3 3.4 1.6 1.0 0.8 0.1 2.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205128-17246007 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "esophagus: 109.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.8;Extravillous trophoblasts: 14.0;Squamous epithelial cells: 5.6;Urothelial cells: 22.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.2;EFO-21: 2.1;HaCaT: 1.5;RPTEC TERT1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA062294 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA062294: AB_2684741" "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavorable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 0.0 109.5 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.2 0.0 0.0 11.5 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.4 1.4 18.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 4.2 0.0 2.1 0.1 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.6 0.9 0.0 0.0 14.8 0.0 3.9 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 14.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.8 0.0 0.0 0.6 0.3 0.0 0.0 0.3 0.2 0.1 5.6 0.0 0.7 0.0 0.1 0.6 22.5 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 17.0;urinary bladder: 25.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Ionocytes: 6.1;Squamous epithelial cells: 1.1;Urothelial cells: 7.9" "Cancer enriched" "Detected in many" 4 "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 14.0;RT4: 17.4;T-47d: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 17.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.9 3.4 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 25.6 3.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 14.0 0.0 1.4 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.5 0.1 0.1 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 7.9 PAK1IP1 "bA421M1.5, FLJ20624, hPIP1, MAK11, PIP1, WDR84" ENSG00000111845 "PAK1 interacting protein 1" Q9NWT1 6 10694972-10709782 "Predicted intracellular proteins" "Ribosome biogenesis" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030111, HPA030112" Supported Supported Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli "HPA030111: AB_2732454, HPA030112: AB_10603125" "unprognostic (9.41e-2)" "unprognostic (3.79e-1)" "unprognostic (1.67e-2)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.35e-6)" "unprognostic (7.23e-2)" "unprognostic (9.29e-3)" "unprognostic (1.06e-3)" "unprognostic (2.14e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (7.02e-8)" "unprognostic (8.14e-2)" "unprognostic (2.04e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" 13.5 10.3 5.6 7.6 5.7 10.6 12.4 5.7 8.1 9.3 5.5 8.4 4.2 10.3 7.2 16.3 8.4 5.2 9.6 5.7 6.2 9.3 11.3 7.3 7.8 5.7 6.0 8.0 9.6 5.7 6.7 7.0 5.9 37.8 7.3 4.9 9.2 5.7 15.2 8.8 7.1 8.1 5.8 8.2 7.8 5.7 5.9 7.0 7.5 9.7 9.6 11.5 9.9 6.9 35.3 13.7 17.2 29.9 21.3 19.4 24.9 22.4 18.7 33.7 32.9 30.2 15.4 35.6 54.9 19.4 41.4 18.4 35.8 29.2 48.1 20.9 23.3 19.4 12.4 35.2 31.1 54.5 24.3 17.9 25.2 32.6 55.3 11.1 22.9 19.2 60.2 10.0 28.3 21.2 27.4 49.5 37.4 32.7 24.1 27.9 22.4 55.0 24.4 21.0 25.7 22.4 16.8 42.7 51.1 28.9 18.9 19.6 19.6 26.9 19.5 29.2 56.4 23.3 68.7 38.9 11.0 36.3 51.7 2.0 8.1 2.9 9.4 12.4 9.6 10.0 8.3 9.4 11.7 7.2 11.1 13.5 0.4 9.9 10.3 13.7 5.9 6.8 5.6 5.7 5.7 8.1 5.7 6.2 5.7 6.0 5.9 5.8 5.9 6.9 22.6 19.2 12.3 8.8 18.5 66.4 54.2 47.3 30.1 13.2 18.6 28.3 18.6 17.2 35.0 11.0 4.2 24.9 24.8 10.3 19.6 43.3 12.4 26.0 35.0 24.1 5.4 31.1 9.9 26.9 32.0 32.0 14.8 34.3 35.5 16.6 15.0 21.7 36.6 13.5 10.9 12.7 42.7 16.1 12.6 8.4 21.5 18.2 12.4 6.5 22.1 12.0 12.3 9.5 12.5 31.3 7.7 20.7 18.2 56.5 5.1 27.0 17.7 11.8 6.6 40.9 31.4 27.3 44.2 29.3 49.9 17.5 16.3 23.1 24.0 28.6 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537370-9839076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.0;retina: 4.7" "Group enriched" "Detected in some" 4 "Breast myoepithelial cells: 6.5;Glandular and luminal cells: 2.0;Granulosa cells: 5.8" "Cancer enhanced" "Detected in single" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 4.6;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.0 1.9 3.6 0.0 4.8 0.0 0.4 12.0 8.4 0.1 0.0 0.0 0.0 0.2 0.6 0.2 0.0 1.2 0.0 5.5 0.7 0.2 0.7 0.0 0.0 0.3 1.4 0.0 1.3 0.0 1.2 0.0 0.4 0.4 0.0 4.7 0.3 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.2 2.1 0.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.8 12.0 8.4 5.5 0.7 0.3 1.4 0.4 0.2 2.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.5;retina: 63.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Oligodendrocytes: 62.0;Rod photoreceptor cells: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" 4.3 8.1 54.4 6.9 80.8 15.7 4.3 80.0 65.3 3.6 32.7 6.5 6.2 2.3 0.5 11.3 3.7 6.9 9.3 55.1 56.4 3.9 3.4 7.9 8.7 93.0 77.4 0.7 11.9 38.4 2.1 2.6 85.9 11.8 5.6 63.7 22.7 1.4 17.6 16.1 6.3 3.5 68.1 7.9 10.5 3.2 74.6 11.0 3.3 27.9 10.3 2.5 4.6 124.5 36.9 30.9 34.4 49.5 5.6 10.0 11.3 13.9 16.6 24.9 23.5 18.8 38.3 36.8 18.3 16.1 17.5 50.8 36.1 21.7 10.4 38.8 16.3 11.5 63.6 25.4 0.6 24.1 39.2 2.4 11.3 13.5 3.5 12.6 16.7 30.7 22.5 95.6 21.7 73.8 35.1 25.8 29.1 55.3 21.6 69.5 45.0 117.6 17.5 12.4 77.3 36.0 51.2 48.5 37.3 4.6 51.6 37.2 10.3 43.0 26.3 20.0 19.8 42.2 30.7 49.3 19.1 32.4 48.4 0.0 0.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 3.6 0.2 0.0 0.3 54.4 80.8 80.0 65.3 55.1 56.4 93.0 77.4 85.9 68.1 74.6 124.5 4.8 0.0 0.0 13.4 2.0 3.1 1.6 2.6 2.2 14.9 5.2 5.2 1.1 12.8 7.8 0.0 58.4 2.2 2.0 5.1 0.0 5.2 0.8 3.0 1.5 4.5 4.2 12.6 8.9 11.3 8.9 2.0 2.6 5.2 2.5 4.6 3.9 0.3 13.3 6.7 4.5 5.5 6.1 7.6 4.6 3.6 0.6 7.2 5.4 2.8 2.2 27.8 2.1 4.5 62.0 9.5 2.5 0.0 5.5 5.0 2.2 1.0 11.0 153.4 0.0 0.3 3.5 1.5 6.3 4.1 5.1 0.5 1.8 1.0 10.9 1.0 PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 19.2;B-cells: 88.4;dendritic cells: 38.6;granulocytes: 19.6;NK-cells: 21.6;Plasma cells: 18.6;T-cells: 31.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.6;JURKAT: 5.1;REH: 3.5;THP-1: 3.7;TIME: 8.9" "Low region specificity" "Detected in single" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 3.7 1.2 3.1 25.7 2.7 23.1 1.8 4.2 3.8 1.7 1.2 3.8 2.6 1.9 1.3 2.0 2.0 4.4 1.7 2.1 1.2 1.7 3.2 9.0 44.4 1.8 2.3 0.7 0.8 0.2 0.7 2.5 1.7 1.8 4.8 2.2 2.2 1.1 6.0 1.2 42.1 1.9 0.7 67.2 4.1 2.5 2.0 8.3 3.0 1.9 50.3 4.5 1.6 3.6 0.3 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.7 0.3 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.7 0.1 7.6 0.5 0.3 0.1 0.5 0.3 1.5 0.1 0.3 0.1 0.2 1.7 5.1 0.2 1.3 0.0 0.3 2.3 0.4 0.4 0.1 0.1 3.5 0.2 0.3 0.0 0.6 0.5 0.3 0.1 0.1 0.1 0.3 0.5 3.7 8.9 0.2 0.6 0.3 0.2 0.6 0.4 1.6 0.4 0.2 0.1 1.8 0.2 0.1 7.2 0.3 5.8 9.4 4.4 5.4 0.8 9.3 3.8 4.8 0.5 3.9 0.7 1.0 4.2 2.2 3.1 2.7 4.2 3.8 2.1 1.2 1.8 2.3 1.7 0.7 2.0 3.6 0.8 19.2 15.9 0.0 88.4 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 2.1 0.0 0.0 0.1 38.6 0.1 0.0 0.0 0.2 0.3 0.1 1.2 0.0 7.4 0.1 0.0 0.1 2.7 2.6 0.3 19.6 0.0 2.2 0.6 8.3 0.0 0.2 0.0 0.0 5.1 1.4 0.2 0.0 6.4 1.8 6.5 4.7 0.0 21.6 0.0 0.1 0.1 0.0 0.0 18.6 0.0 0.0 0.1 10.5 0.0 0.0 0.7 0.4 0.1 1.6 0.4 0.0 0.3 31.1 0.0 0.0 0.0 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 56.9;dendritic cells: 51.7;granulocytes: 60.1;Hofbauer cells: 66.7;Kupffer cells: 87.3;Langerhans cells: 53.4;Macrophages: 91.9;monocytes: 62.0;T-cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HL-60: 116.4;NB-4: 44.9;THP-1: 64.7;U-937: 53.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" 3.5 2.9 3.7 26.7 3.5 49.7 1.8 4.4 7.1 2.6 4.0 3.1 3.6 2.4 0.6 2.5 2.2 6.2 1.3 3.8 4.7 1.8 3.1 10.4 30.1 8.2 4.9 0.8 1.4 0.5 1.3 3.0 6.9 2.1 3.4 0.2 2.6 1.1 1.2 1.7 12.7 2.9 5.9 28.9 4.4 1.7 7.9 18.4 1.9 0.4 26.8 4.7 1.5 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 116.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 16.8 44.9 0.1 0.0 0.0 9.2 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 64.7 0.0 0.0 11.5 0.2 0.0 0.3 0.0 0.3 0.0 53.9 1.9 12.5 62.0 71.3 13.9 57.6 13.9 21.4 8.0 15.2 49.2 20.4 8.9 10.3 72.2 13.1 65.9 33.3 12.1 44.6 3.7 3.5 4.4 7.1 3.8 4.7 8.2 4.9 6.9 5.9 7.9 9.4 1.3 6.4 14.0 1.0 56.9 2.4 0.1 0.0 0.6 0.2 0.7 1.5 1.1 0.0 3.1 0.0 0.0 0.6 51.7 0.1 0.0 0.0 4.2 3.7 0.4 2.9 0.0 10.1 3.9 0.2 0.7 2.3 3.6 2.5 60.1 0.0 3.9 1.3 66.7 0.0 2.9 0.0 0.0 87.3 53.4 2.7 0.0 91.9 5.4 10.3 62.0 0.0 26.8 0.0 1.4 0.0 0.0 0.0 15.9 0.0 0.0 0.5 1.5 0.2 0.0 0.5 0.4 1.1 0.8 0.4 1.8 1.0 48.3 0.0 0.1 0.1 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 24.5;Theca cells: 26.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.6 1.1 3.7 7.1 19.8 8.8 2.1 1.0 5.3 2.5 3.1 2.4 3.4 2.1 3.9 3.3 6.1 2.0 1.1 2.7 1.7 3.7 1.4 3.2 13.7 1.9 1.9 1.9 3.6 2.4 4.6 1.0 1.8 10.0 2.3 11.9 2.9 1.4 0.8 4.1 4.5 1.2 0.3 4.1 3.0 16.1 3.2 22.9 5.1 0.2 7.8 2.1 2.2 5.2 7.4 9.9 12.9 16.7 1.1 1.9 17.4 7.0 2.2 6.3 8.8 8.1 7.4 3.8 1.4 1.5 13.8 17.9 15.1 6.1 4.6 15.6 13.8 10.6 19.1 14.4 0.8 14.7 16.0 0.9 4.7 6.5 1.9 2.6 4.6 16.2 14.0 5.2 4.5 8.0 17.5 15.4 14.6 8.8 5.9 27.5 13.3 4.7 2.5 16.0 23.1 7.0 3.9 8.0 3.2 6.8 6.7 10.5 6.1 8.8 7.7 11.1 9.6 6.8 7.4 18.1 5.4 10.9 8.2 4.4 0.6 0.5 1.0 0.4 0.9 4.5 3.9 3.5 0.8 3.9 2.3 2.6 0.8 1.9 0.7 0.4 4.1 2.2 3.7 19.8 1.0 5.3 2.7 1.7 1.9 1.9 1.8 0.3 3.2 5.2 2.3 3.2 7.9 2.6 8.5 2.7 1.2 1.6 2.2 2.6 3.5 4.3 3.1 2.8 1.9 3.7 4.2 0.9 2.2 3.1 0.0 1.5 14.9 13.9 1.6 8.5 0.0 13.3 12.5 2.0 1.7 2.7 3.6 4.4 3.8 11.7 17.5 1.5 2.0 1.7 6.1 3.5 0.0 4.7 2.0 3.5 5.9 2.1 12.4 3.7 2.7 2.1 7.2 0.5 2.6 0.9 1.0 24.5 4.7 1.7 1.9 1.4 12.3 18.7 0.0 2.1 2.1 16.1 12.7 2.6 1.4 0.3 19.1 26.5 3.9 0.9 PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Alveolar cells type 2: 60.6;Club cells: 39.0;Collecting duct cells: 57.0;Endometrial ciliated cells: 55.7;Glandular and luminal cells: 98.3;Pancreatic endocrine cells: 47.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 75.0" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 36.3;RPTEC TERT1: 30.3;RT4: 33.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 72.3" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: AB_2685663, HPA066960: AB_2685755, HPA069079: AB_2686079" "unprognostic (1.81e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (7.60e-2)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-3)" "unprognostic (2.99e-2)" "prognostic favorable (1.47e-5)" "unprognostic (3.05e-3)" "unprognostic (6.72e-3)" "unprognostic (2.21e-2)" "unprognostic (2.43e-1)" 3.4 7.2 6.8 3.6 5.4 3.5 18.1 75.0 5.3 8.4 25.3 12.2 8.9 5.8 26.5 19.3 8.3 7.1 45.2 3.8 9.2 27.5 12.4 10.0 2.9 12.8 9.0 6.8 12.4 20.0 10.9 3.5 14.2 12.3 11.1 15.8 20.0 7.9 45.4 22.4 9.3 3.5 11.5 3.1 10.2 5.1 9.1 4.0 13.1 16.1 6.2 7.9 13.2 9.5 36.3 7.0 2.3 3.2 1.3 3.3 29.5 2.1 2.8 2.2 3.0 12.5 13.2 0.2 9.1 4.4 18.7 21.1 5.1 18.9 3.8 3.5 8.8 0.2 10.4 11.3 2.9 0.1 0.2 1.2 19.7 3.7 8.0 5.3 1.2 0.0 0.0 0.0 1.9 12.6 0.1 0.1 12.0 16.4 1.9 0.1 2.8 5.2 30.3 33.4 6.1 2.0 8.8 29.4 7.7 23.7 23.7 0.3 0.3 1.8 4.3 0.2 4.2 1.4 2.7 4.8 1.7 0.0 0.5 0.4 0.0 7.2 1.2 0.1 2.3 1.2 2.0 1.7 0.0 1.1 2.6 1.7 0.6 2.6 0.1 0.2 1.9 0.6 6.8 5.4 75.0 5.3 3.8 9.2 12.8 9.0 14.2 11.5 9.1 9.5 6.4 86.6 60.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 35.0 29.8 0.0 0.0 39.0 57.0 0.0 4.3 3.8 0.0 5.9 37.6 0.0 55.7 8.6 1.6 0.0 0.0 0.0 26.4 0.7 5.5 0.0 98.3 1.3 14.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 2.7 0.0 0.0 35.7 27.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 26.4 10.3 1.7 0.0 0.0 PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.2;dendritic cells: 19.1;NK-cells: 51.5;Plasma cells: 15.7;T-cells: 29.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cell line enriched" "Detected in some" 28 "U-266/70: 124.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" 0.9 1.1 0.8 7.7 1.1 7.7 1.3 0.6 0.8 0.3 1.5 2.1 2.4 1.1 1.7 0.6 1.4 2.3 0.7 0.7 0.8 0.5 1.7 3.9 17.2 1.8 1.1 0.9 0.6 0.4 0.2 1.0 1.1 0.8 2.5 0.1 2.5 0.6 0.3 2.7 3.2 0.8 0.9 13.9 3.2 0.5 1.2 3.6 0.7 0.0 10.8 2.1 0.2 1.4 0.2 0.0 0.0 0.1 0.0 1.1 2.8 0.1 0.4 0.9 0.9 0.6 1.2 0.9 0.1 0.3 1.8 1.3 0.1 0.2 0.5 2.1 0.0 1.2 0.0 0.1 0.5 0.5 0.7 1.2 0.1 0.5 0.3 0.2 0.0 1.4 0.2 4.5 0.3 0.3 0.1 1.4 0.4 0.1 0.1 1.8 0.0 0.5 0.1 0.4 0.1 0.0 0.0 1.3 0.1 0.2 0.1 0.9 0.6 0.3 0.0 0.8 0.0 124.9 4.3 0.4 1.2 3.1 0.4 1.5 0.3 2.6 21.6 0.7 3.2 3.3 6.0 17.7 0.7 3.5 3.6 12.8 1.6 2.7 0.5 0.6 0.9 3.7 0.8 1.1 0.6 0.8 0.7 0.8 1.8 1.1 1.1 0.9 1.2 1.4 1.4 3.2 1.7 1.6 29.2 0.9 0.6 0.5 0.6 0.0 0.6 0.6 11.7 0.0 0.4 0.0 0.0 0.2 19.1 2.0 0.0 0.4 0.3 2.4 1.0 1.8 0.0 3.0 0.3 0.6 0.5 1.9 8.2 0.8 0.0 1.2 1.4 1.0 2.0 0.0 0.4 1.4 0.0 4.8 2.3 0.0 0.3 5.6 0.0 3.7 5.2 0.0 51.5 0.5 1.3 0.4 0.3 0.0 15.7 0.6 2.2 0.4 8.5 0.0 0.0 1.0 2.6 0.1 0.4 1.4 0.9 0.3 29.8 1.8 0.9 1.3 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDH8 "ARCADLIN, PAPC" ENSG00000136099 "Protocadherin 8" O95206 13 52842889-52848641 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "brain: 28.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 18.2;Excitatory neurons: 24.8;Inhibitory neurons: 18.6;Muller glia cells: 25.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Region enhanced" "Detected in many" "hippocampal formation: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AF22: 23.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010509 Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" Cytosol "HPA010509: AB_10601384" "unprognostic (3.50e-3)" "unprognostic (6.48e-2)" "unprognostic (1.40e-1)" "unprognostic (9.11e-4)" "unprognostic (2.12e-2)" "unprognostic (1.97e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "unprognostic (3.59e-1)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" 0.0 0.0 5.8 0.0 12.1 0.0 0.0 0.0 19.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 4.5 0.0 0.0 0.0 0.0 1.1 1.2 0.0 0.0 0.0 1.4 0.0 1.3 1.0 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.0 5.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 12.1 0.0 19.7 28.4 4.5 1.1 1.2 1.3 5.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.1 2.1 0.0 0.0 18.2 0.4 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 24.8 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 18.6 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 3.7 0.0 25.8 0.0 2.5 2.2 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.4 0.1 2.7 2.8 0.0 0.0 0.0 0.0 0.0 0.1 1.1 PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.1;Early spermatids: 8.1;Horizontal cells: 13.5;Peritubular cells: 8.6;Spermatocytes: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.4;SiHa: 12.0;U-2197: 8.5" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" 3.1 2.8 2.3 0.8 3.2 0.1 3.5 2.1 4.0 6.0 0.0 4.6 0.3 7.0 2.4 2.0 4.3 1.9 4.4 2.6 1.3 2.1 1.2 3.0 0.4 1.5 2.3 4.7 4.0 3.6 6.2 1.1 0.7 3.1 0.9 2.3 3.6 1.9 1.6 4.4 1.6 2.6 1.6 2.0 1.9 2.5 3.1 0.4 2.2 1.5 0.3 3.5 3.5 3.3 0.0 0.0 3.3 6.3 5.4 6.4 0.4 0.5 5.5 0.5 1.7 0.1 1.0 0.3 4.5 1.5 2.9 0.3 0.7 1.0 0.5 0.0 0.1 0.0 1.3 0.1 0.2 0.3 0.2 1.2 4.7 0.1 0.2 4.8 0.6 0.2 0.0 5.8 2.3 0.5 0.4 0.0 0.4 0.0 1.1 3.8 4.1 0.0 0.1 0.2 7.6 14.4 12.0 0.3 1.3 0.5 6.1 0.5 1.7 2.2 1.9 8.5 2.2 0.0 0.1 0.1 4.5 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.1 4.0 2.6 1.3 1.5 2.3 0.7 1.6 3.1 3.3 4.1 0.0 4.8 0.0 0.0 0.4 1.1 3.1 0.0 15.1 1.6 2.4 3.3 0.0 3.1 1.8 0.0 0.0 0.2 0.3 0.0 0.9 8.1 0.8 6.3 3.9 3.5 0.0 0.0 2.4 0.0 5.0 0.0 0.9 0.0 1.3 3.3 1.3 0.1 13.5 0.0 0.6 4.1 0.0 0.7 2.1 3.4 0.3 0.0 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.5 8.6 0.0 0.5 0.0 0.8 0.6 1.3 0.0 6.3 3.9 8.0 0.1 0.7 2.8 0.0 0.2 2.5 0.3 0.7 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 9.7;Endometrial stromal cells: 8.2;Fibroblasts: 9.5;Horizontal cells: 8.4;Peritubular cells: 6.4;Skeletal myocytes: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.7;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" 3.2 2.1 2.7 0.7 3.0 0.0 3.4 3.3 3.7 3.6 0.3 2.0 0.6 5.4 3.8 1.5 4.0 2.4 2.3 3.2 4.2 1.5 0.3 2.1 0.4 5.0 3.7 4.2 8.5 1.4 2.7 0.1 5.7 2.4 0.9 1.6 2.1 1.9 1.6 1.3 0.9 3.3 5.0 0.7 1.3 0.5 2.7 0.4 1.5 2.1 0.2 2.1 2.1 6.7 0.0 0.0 0.3 1.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.7 5.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 3.0 3.3 3.7 3.2 4.2 5.0 3.7 5.7 5.0 2.7 6.7 9.7 0.0 0.5 0.0 0.0 1.1 0.4 0.2 0.6 4.9 2.6 3.8 1.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 8.2 4.3 0.0 0.0 0.0 1.7 0.0 9.5 0.0 0.3 0.0 0.1 3.6 0.0 0.1 8.4 0.0 0.0 2.0 0.0 1.1 0.0 1.5 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 0.6 0.0 6.4 0.0 0.7 0.0 0.0 2.5 0.6 0.0 8.7 4.0 1.4 0.5 0.0 2.0 0.0 0.0 0.5 0.0 0.4 PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Early spermatids: 38.4;Late spermatids: 27.3;Spermatocytes: 24.5" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.9;EFO-21: 4.8;U-138 MG: 3.2;U-2197: 9.6;U-87 MG: 3.3;WM-115: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" 1.7 0.7 0.5 0.9 0.6 0.0 2.0 0.6 1.6 2.9 0.0 1.5 0.4 4.5 1.6 0.3 2.6 1.5 1.6 1.0 0.7 1.0 0.3 2.0 0.2 1.7 1.2 2.3 0.4 0.3 2.4 0.2 1.2 1.1 0.4 1.4 0.6 1.0 0.4 0.7 0.8 3.1 0.9 0.7 0.7 2.0 0.6 0.2 1.0 0.6 0.2 1.3 1.5 1.0 0.0 0.0 0.4 0.4 3.9 1.9 0.0 0.2 0.5 0.1 0.1 0.0 0.1 0.0 4.8 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 1.4 1.0 0.3 0.0 0.8 0.0 2.1 0.0 0.7 3.2 0.6 9.6 0.1 0.0 0.0 0.0 3.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 1.6 1.0 0.7 1.7 1.2 1.2 0.9 0.6 1.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 4.9 0.2 0.5 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 38.4 0.3 2.4 1.1 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 1.7 0.0 0.0 6.1 0.0 0.0 27.3 0.9 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.3 6.6 3.4 2.1 24.5 0.7 0.0 0.9 0.1 0.0 0.3 0.0 0.0 PCDHB9 "PCDH-BETA9, PCDH3H" ENSG00000177839 "Protocadherin beta 9" Q9Y5E1 5 141187127-141191541 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Bipolar cells: 20.2;Horizontal cells: 10.1;Skeletal myocytes: 6.3" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;ASC diff: 10.3;ASC TERT1: 9.4;SH-SY5Y: 14.3" HPA013445 Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "HPA013445: AB_1855054" "unprognostic (1.85e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-1)" "unprognostic (8.97e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.12e-1)" "unprognostic (6.78e-3)" "unprognostic (1.34e-2)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (1.86e-4)" "unprognostic (1.71e-1)" "unprognostic (9.80e-2)" "unprognostic (1.17e-1)" "unprognostic (8.01e-2)" 1.0 0.8 0.6 0.1 1.0 0.1 1.2 1.1 1.9 1.5 0.0 1.1 0.1 2.0 1.8 0.3 1.3 0.7 1.1 1.4 0.2 0.5 0.2 1.1 0.1 0.3 0.6 2.0 0.7 1.1 2.4 0.5 0.4 0.6 0.2 1.2 1.0 0.3 0.4 0.8 0.4 1.2 0.3 0.3 0.5 0.8 0.9 0.2 0.6 1.0 0.1 0.8 0.9 0.9 0.0 0.0 0.9 6.0 10.3 9.4 0.2 0.1 3.5 0.4 0.5 0.0 1.0 0.4 3.9 0.2 2.8 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.9 0.0 0.0 1.8 0.0 0.1 0.0 2.7 3.1 0.9 0.6 0.7 0.3 0.0 0.4 2.8 5.4 0.0 0.6 0.1 2.1 14.3 0.6 0.1 1.0 0.4 2.6 0.2 0.9 5.2 0.5 4.7 1.2 0.0 0.0 0.0 3.1 0.2 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 1.0 1.1 1.9 1.4 0.2 0.3 0.6 0.4 0.3 0.9 0.9 1.8 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 20.2 0.5 1.4 0.2 1.5 1.3 1.8 0.0 0.0 0.0 0.2 0.0 0.4 1.0 0.2 2.8 1.3 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.1 0.0 0.0 1.8 0.2 0.1 10.1 0.0 0.1 0.0 0.3 0.0 0.4 1.5 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 1.9 0.0 0.2 0.0 0.3 0.0 0.7 0.0 6.3 1.8 1.0 0.2 0.3 0.0 0.0 0.1 0.3 0.0 0.1 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 647.3;seminal vesicle: 1280.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 600.9;Distal tubular cells: 645.6;Horizontal cells: 1398.2;Proximal tubular cells: 941.2" "Cancer enhanced" "Detected in many" "prostate cancer: 41.7;thyroid cancer: 48.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 215.9;T-47d: 64.7" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: AB_1855086" "unprognostic (6.82e-2)" "prognostic favorable (9.76e-4)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.63e-1)" "prognostic favorable (1.85e-7)" "unprognostic (9.00e-2)" "unprognostic (2.99e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" 5.2 52.9 197.6 2.0 647.3 0.0 8.4 166.2 202.0 180.9 509.6 135.5 5.1 126.9 365.6 228.2 10.2 4.2 4.6 121.8 175.9 52.1 0.5 0.6 0.2 75.6 299.1 3.5 6.2 19.7 8.8 2.0 70.2 323.4 32.4 385.3 21.3 1280.1 0.6 14.8 6.0 54.6 64.1 2.6 7.1 0.9 491.1 7.9 227.7 0.0 1.0 468.0 128.6 85.5 0.0 0.0 3.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 2.3 1.9 0.0 0.0 0.0 0.0 215.9 0.5 0.0 0.3 0.3 0.0 34.8 0.0 0.2 64.7 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.6 647.3 166.2 202.0 121.8 175.9 75.6 299.1 70.2 64.1 491.1 85.5 0.0 0.0 1.5 15.3 2.9 3.1 0.4 0.0 0.0 600.9 0.4 0.4 8.8 2.8 0.0 77.3 62.6 0.3 0.0 0.1 645.6 0.4 1.3 0.0 0.2 5.0 1.2 0.0 71.3 0.2 0.3 1.5 0.0 0.0 0.0 0.4 0.0 0.1 0.2 1398.2 21.5 0.2 0.0 0.0 7.5 0.4 9.6 7.0 21.4 8.4 0.0 68.4 0.0 7.5 11.9 0.8 0.2 0.4 0.0 4.4 0.0 941.2 0.0 200.0 0.0 0.0 77.4 3.4 9.5 0.0 6.0 2.9 2.2 0.5 0.5 1.0 PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Bipolar cells: 82.8;Inhibitory neurons: 34.0;Sertoli cells: 19.7;Squamous epithelial cells: 23.5;Urothelial cells: 39.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RT4: 13.8;T-47d: 8.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" 2.7 0.4 14.1 0.8 71.7 0.1 1.8 19.6 33.2 4.0 0.9 5.6 1.7 1.8 2.6 18.8 2.1 2.0 0.8 6.8 14.7 0.9 4.0 4.6 0.2 39.7 23.3 2.2 0.5 0.4 84.3 0.3 39.8 11.0 2.5 39.2 1.9 16.4 0.4 5.6 2.8 6.6 28.1 0.3 2.0 1.8 15.2 2.0 0.7 1.5 2.6 35.6 17.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 13.8 1.9 0.0 0.0 0.2 0.0 0.2 8.9 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 14.1 71.7 19.6 33.2 6.8 14.7 39.7 23.3 39.8 28.1 15.2 13.9 0.0 3.2 6.4 2.0 0.0 0.0 35.8 8.3 12.5 82.8 3.2 1.0 0.2 0.0 7.6 0.0 6.2 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.1 1.3 1.9 0.2 4.6 0.3 1.3 0.0 0.0 0.9 0.1 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 3.5 0.0 5.0 1.4 0.2 0.0 1.9 0.0 2.5 0.0 0.6 0.9 5.9 19.7 0.0 10.0 1.3 1.5 23.5 0.3 1.8 0.0 0.0 0.0 39.9 PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 189.7;Inhibitory neurons: 81.9;NK-cells: 82.4;Oligodendrocyte precursor cells: 149.3;Proximal enterocytes: 99.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 2447.1;neutrophil: 626.3" "Lineage enriched" "Detected in all" 18 "granulocytes: 2447.1" "Cell line enhanced" "Detected in many" "BEWO: 32.6;HaCaT: 46.9;RH-30: 30.4;RPTEC TERT1: 42.5;U-2 OS: 66.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 290000 "Cluster 41: Basophils - Cellular respiration" "Cluster 45: Intestine - Brush border" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" 17.6 4.2 6.6 5.9 6.6 2.3 6.9 22.2 23.8 9.0 0.0 10.2 25.0 7.1 9.6 8.5 6.9 8.6 5.3 7.4 7.8 3.8 1.7 6.1 2.7 21.7 17.3 13.5 3.0 5.9 2.3 9.4 20.0 3.3 8.4 6.0 3.5 3.0 3.0 3.6 26.4 6.6 23.0 3.3 3.3 6.3 5.3 9.1 4.8 5.4 2.5 5.3 8.8 2.4 2.5 1.8 5.1 3.4 3.2 1.0 32.6 4.7 0.4 0.3 0.0 18.7 2.0 0.8 1.3 0.6 0.1 46.9 2.4 1.4 0.3 0.6 4.1 6.3 4.5 1.6 0.8 1.9 2.8 6.0 0.4 1.0 0.5 0.3 9.6 3.1 7.5 2.4 3.3 11.5 7.4 11.1 22.8 4.3 1.9 1.3 30.4 1.9 42.5 2.9 0.7 0.5 7.1 1.5 0.5 9.5 2.6 8.0 7.6 1.5 66.5 3.8 2.0 0.7 0.3 1.0 5.1 2.7 25.7 2447.1 43.1 192.4 100.0 25.9 85.2 92.3 100.8 93.7 21.8 116.5 98.2 125.2 626.3 135.5 51.6 135.0 96.9 10.1 6.6 6.6 22.2 23.8 7.4 7.8 21.7 17.3 20.0 23.0 5.3 2.4 41.1 6.4 7.2 189.7 0.1 6.5 3.5 8.6 13.6 4.8 0.7 2.0 5.8 11.5 14.3 5.5 0.0 2.1 9.6 47.3 0.0 8.2 19.0 6.0 35.1 19.5 1.2 0.0 33.5 6.1 34.3 26.6 9.7 10.6 0.0 32.1 15.0 0.9 2.9 55.5 81.9 10.2 6.1 4.1 3.9 39.4 20.5 7.5 1.8 70.3 11.4 30.3 82.4 149.3 5.8 10.1 18.5 25.2 0.4 2.9 99.2 4.2 23.4 1.4 19.7 9.1 11.4 1.0 1.9 6.2 3.0 2.5 6.2 5.6 23.9 0.9 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2;retina: 12.1;testis: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 23.5;Early spermatids: 29.1;Late spermatids: 90.1;Muller glia cells: 30.1;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 41.9" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 22.2;HEL: 25.7;Hep G2: 10.2;NTERA-2: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.1 0.8 12.1 0.2 12.2 0.8 0.1 10.6 12.8 0.7 7.5 1.2 0.3 1.6 0.6 0.8 2.2 0.4 2.9 13.2 9.8 0.2 0.0 0.7 0.0 9.5 10.2 1.4 1.5 0.0 1.3 1.3 9.8 0.8 0.2 12.1 0.1 2.4 0.0 0.1 0.6 2.5 8.6 0.2 0.2 13.4 11.4 0.5 0.0 0.0 0.0 0.3 0.3 12.9 0.0 0.0 10.3 0.1 0.0 0.0 0.1 0.0 0.9 0.3 0.1 22.2 0.0 0.0 5.2 0.0 0.0 1.0 4.2 0.0 0.0 0.0 0.1 25.7 0.0 10.2 0.1 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 3.9 0.5 11.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 7.2 5.8 0.0 0.0 0.5 7.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.4 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 12.1 12.2 10.6 12.8 13.2 9.8 9.5 10.2 9.8 8.6 11.4 12.9 0.0 0.0 0.0 23.5 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.5 1.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.8 29.1 10.7 0.2 0.1 1.8 1.3 5.6 0.0 0.0 0.4 0.0 0.2 4.5 5.8 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 90.1 0.3 0.9 0.0 3.7 0.3 30.1 0.0 23.6 41.9 0.2 0.0 2.6 0.1 0.1 0.0 0.5 6.4 1.6 0.0 0.0 1.0 1.8 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.1 PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 4 "Plasma cells: 9.5;T-cells: 34.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;MOLT-4: 2.4;RPMI-8226: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" 1.2 0.3 0.0 3.2 0.2 0.9 0.4 0.0 0.1 0.6 0.2 0.8 0.3 0.4 0.0 0.8 0.6 0.3 6.7 0.1 0.1 0.7 0.4 1.8 16.1 0.1 1.4 0.2 0.3 0.0 1.5 0.0 0.2 0.7 0.1 0.0 1.0 0.2 0.1 0.3 3.8 0.2 0.1 7.0 1.8 0.3 0.4 3.1 1.5 0.0 4.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 4.8 0.2 8.7 12.4 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 4.3 2.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 1.4 0.2 0.1 0.4 0.2 0.4 0.0 0.6 0.0 3.6 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.6 0.0 34.7 0.0 0.0 0.1 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018469: AB_1855116, HPA027094: AB_10601387" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.32e-2)" "unprognostic (5.07e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.07e-5)" "unprognostic (1.44e-1)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (8.22e-2)" "prognostic favorable (4.23e-4)" 20.8 22.0 19.1 27.1 21.6 22.9 23.0 21.6 24.3 18.9 16.6 27.3 17.0 24.1 37.2 36.8 22.5 21.3 30.6 18.4 21.3 28.4 18.5 18.4 25.3 21.8 24.7 21.1 11.4 23.4 10.5 23.4 21.7 27.0 28.9 21.1 16.9 23.2 58.8 36.8 17.3 38.6 20.8 17.0 17.6 22.8 22.1 22.4 21.4 34.3 34.0 33.1 17.5 22.2 41.8 58.7 59.9 52.2 19.3 27.4 67.5 51.3 32.5 92.9 58.1 74.2 25.5 68.6 74.0 62.3 122.3 34.2 76.0 50.2 74.0 110.6 65.8 72.0 31.8 89.7 50.8 77.3 73.2 29.8 92.0 82.0 52.3 24.2 58.9 52.8 61.1 43.8 70.7 74.6 75.8 117.7 77.9 45.6 86.6 72.5 63.2 48.0 58.2 98.7 55.9 49.6 41.0 54.7 59.0 48.6 42.3 53.0 45.8 56.4 60.1 44.8 72.2 26.4 54.1 68.3 34.4 90.5 45.7 82.3 64.8 80.2 63.1 124.4 72.8 92.5 95.0 70.4 114.9 78.1 97.7 75.4 7.0 93.9 161.7 64.0 113.6 87.3 19.1 21.6 21.6 24.3 18.4 21.3 21.8 24.7 21.7 20.8 22.1 22.2 37.4 19.2 25.2 1.6 39.5 65.6 36.6 79.2 52.9 13.0 24.8 36.2 40.9 18.6 46.1 14.7 6.2 70.8 61.5 16.0 60.7 50.6 37.0 38.9 26.6 30.2 19.8 21.7 2.3 39.1 51.2 22.6 19.4 34.6 92.9 25.4 12.5 17.0 59.7 11.8 2.0 24.0 89.5 17.8 80.7 14.3 14.6 54.4 35.6 3.7 104.3 19.7 40.2 2.0 4.5 31.8 18.6 33.4 27.7 33.2 19.7 77.9 28.1 16.5 52.6 23.8 54.1 5.5 66.9 63.2 57.5 52.4 91.8 24.5 31.3 32.4 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178072777 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.3;parathyroid gland: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8" HPA034560 Approved "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.3 0.3 0.8 0.1 2.0 0.2 1.7 1.9 1.2 0.6 0.6 0.5 0.8 1.2 0.4 0.0 0.3 0.4 0.3 0.6 2.1 0.5 6.3 0.0 0.0 2.5 2.1 0.4 1.1 9.8 0.9 0.0 2.7 5.2 0.4 1.4 1.4 0.8 4.4 0.1 0.5 1.1 3.7 0.1 0.4 2.8 1.9 0.1 1.3 1.3 0.0 0.0 0.1 3.2 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.2 1.6 0.0 0.6 2.4 0.3 0.1 1.4 0.0 0.0 0.0 0.9 1.1 0.1 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.2 0.2 0.4 0.1 0.6 0.0 0.3 0.2 0.0 0.2 0.0 0.5 0.0 0.3 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.8 2.0 1.9 1.2 0.6 2.1 2.5 2.1 2.7 3.7 1.9 3.2 0.1 0.0 0.0 2.3 0.2 0.6 1.4 0.1 0.0 1.7 4.2 0.8 0.0 1.5 0.1 0.0 0.0 0.1 0.3 0.8 0.0 0.8 37.0 0.3 0.2 0.6 6.7 2.7 1.6 6.7 0.0 0.6 0.0 0.2 0.0 0.0 1.4 11.1 0.1 0.0 8.2 0.9 6.1 1.2 2.1 46.4 1.5 0.3 0.0 0.0 0.0 4.7 0.0 6.0 14.9 2.3 0.0 0.7 0.0 5.4 0.6 1.3 0.1 1.0 0.0 2.0 0.6 6.8 6.9 0.0 1.3 0.3 0.3 0.3 1.3 1.0 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1071.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.4 1.8 19.2 2.5 43.0 0.0 4.3 21.4 39.9 0.7 0.0 3.0 1.4 2.4 6.0 6.4 10.5 1.5 58.5 18.9 24.2 4.2 0.1 4.9 0.6 29.4 27.9 3.8 2.6 0.3 1.3 3.2 27.7 2.0 1.8 7.4 1.8 3.2 0.6 0.4 3.3 5.0 16.4 0.6 4.0 3.8 28.6 1.6 3.1 4.0 0.1 9.8 1.4 68.9 0.3 5.8 15.5 0.0 0.6 0.4 0.2 44.4 18.3 20.8 17.1 0.0 0.0 0.0 0.2 148.3 0.0 1.2 0.0 0.0 27.1 0.0 0.0 1.3 1.4 0.0 0.1 0.0 31.9 1.9 0.0 4.3 0.2 44.9 7.1 0.0 0.1 0.1 1.7 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 22.5 0.0 6.8 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.2 22.8 8.6 0.4 77.9 0.4 0.0 0.0 2.4 0.5 105.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 43.0 21.4 39.9 18.9 24.2 29.4 27.9 27.7 16.4 28.6 68.9 1.2 0.0 0.0 7.5 0.1 0.0 0.7 0.1 1.2 69.5 2.8 17.1 136.0 0.0 0.7 1.8 52.1 0.0 0.1 0.0 0.0 4.8 53.4 0.2 0.1 3.9 0.0 0.0 70.8 0.4 0.0 8.7 0.0 0.4 8.8 0.2 0.0 0.0 0.1 3.3 169.2 0.0 59.0 0.0 0.2 50.3 0.3 0.5 0.0 15.9 0.0 0.9 0.0 196.6 1071.4 0.2 0.0 0.4 0.1 0.2 0.0 0.0 2.2 4.7 0.0 0.9 9.4 1.3 1.2 0.2 0.0 0.0 0.1 1.2 0.0 0.0 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77428256 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Astrocytes: 64.9;Excitatory neurons: 183.1;Horizontal cells: 69.0;Inhibitory neurons: 276.5;Muller glia cells: 86.5;Oligodendrocyte precursor cells: 190.5" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 13.6;HeLa: 34.8;SK-BR-3: 11.1" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA036911: AB_2675378, HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 20.9 4.8 24.2 1.0 28.6 0.4 14.0 4.8 24.6 17.4 0.0 5.6 2.0 26.4 6.3 2.0 28.7 4.3 23.7 25.5 32.5 15.6 2.3 5.2 1.2 20.5 15.9 4.2 7.9 0.8 12.5 23.8 18.8 19.0 1.2 22.5 10.5 11.9 0.7 2.0 3.3 17.7 9.9 0.8 5.5 3.0 36.7 0.3 124.7 0.8 1.0 4.0 4.9 17.2 0.1 4.9 0.8 0.3 1.5 0.0 0.5 1.5 13.6 0.2 0.1 1.4 0.1 0.3 0.1 0.1 0.2 0.6 0.2 0.0 0.2 0.2 0.7 0.4 34.8 0.3 0.0 0.4 0.5 0.8 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.0 0.2 0.5 0.8 0.8 0.2 0.1 0.6 0.9 0.4 0.0 0.2 5.4 1.0 2.3 11.1 0.7 0.7 1.8 0.9 0.5 0.3 0.3 0.2 0.5 0.7 0.5 0.4 1.2 0.5 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 24.2 28.6 4.8 24.6 25.5 32.5 20.5 15.9 18.8 9.9 36.7 17.2 0.8 3.2 2.8 64.9 0.3 0.4 2.0 0.1 0.0 10.8 5.8 3.0 28.0 2.8 1.6 1.8 54.2 0.0 0.2 0.1 0.0 2.3 6.8 15.3 2.1 4.5 4.9 0.0 183.1 0.0 0.1 3.8 0.0 7.9 1.3 1.8 2.9 0.1 0.4 69.0 276.5 1.0 0.0 1.0 1.6 5.1 5.9 0.9 1.8 10.3 0.1 86.5 0.0 190.5 45.5 0.2 0.4 0.0 0.3 29.1 0.2 0.7 0.7 5.8 6.6 1.8 7.7 1.1 2.6 0.5 1.1 0.0 0.1 8.8 1.2 4.2 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 4781.7;tongue: 1519.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 228.9;Ductal cells: 332.7;Melanocytes: 124.5;Peritubular cells: 196.0;Skeletal myocytes: 428.3;Smooth muscle cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 115.6;RH-30: 26.9;U-266/70: 111.2;U-266/84: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Cytosol "HPA004749: AB_1855150" "unprognostic (2.75e-1)" "unprognostic (3.85e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (9.46e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.97e-7)" "unprognostic (1.64e-3)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.78e-3)" 36.3 11.5 12.7 25.7 13.3 0.0 34.5 16.8 14.8 22.7 10.9 201.2 20.8 235.3 59.1 216.2 97.5 40.1 314.0 12.0 15.7 13.9 7.7 55.2 10.7 19.9 14.2 38.1 18.7 0.8 20.7 18.8 13.8 87.0 32.5 11.2 56.3 148.1 4781.7 12.1 69.0 127.6 17.9 24.5 95.8 8.2 14.6 4.1 32.7 1519.6 26.2 141.1 40.8 14.2 0.0 0.0 0.9 0.0 0.3 0.0 0.8 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 0.0 15.1 0.0 0.8 4.7 13.5 0.0 0.0 8.7 0.0 2.6 0.0 12.3 9.1 0.0 0.0 0.0 115.6 0.0 0.0 0.1 2.4 0.0 1.0 0.0 26.9 0.3 0.0 0.0 17.6 13.3 0.0 0.0 7.3 2.8 0.6 0.0 7.9 0.0 7.6 0.1 7.1 111.2 34.8 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 13.3 16.8 14.8 12.0 15.7 19.9 14.2 13.8 17.9 14.6 14.2 22.4 9.6 6.0 37.2 2.6 8.9 11.4 0.7 12.5 12.1 72.8 105.7 228.9 5.7 2.2 0.0 12.5 2.5 0.6 0.2 0.0 332.7 0.4 1.4 0.8 39.0 3.5 0.0 2.5 16.7 2.7 82.9 1.1 1.1 0.0 1.3 67.5 0.9 1.6 5.0 0.5 0.5 2.0 1.8 11.7 2.6 19.6 2.3 124.5 1.0 3.2 36.4 0.0 6.6 2.6 31.2 0.0 196.0 7.3 12.2 0.0 0.2 3.2 44.3 105.2 428.3 131.4 4.0 12.6 2.4 7.1 12.2 2.5 2.4 0.3 3.9 PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 570.3;skeletal muscle: 661.5" "Cell type enhanced" "Detected in many" "Ductal cells: 164.8;Exocrine glandular cells: 242.1;Pancreatic endocrine cells: 320.1;Peritubular cells: 223.0;Sertoli cells: 164.3;Smooth muscle cells: 157.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 177.1;eosinophil: 121.2;neutrophil: 438.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 438.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Actin filaments, Focal adhesion sites" "HPA018794: AB_1855155, HPA048815: AB_2680530" "unprognostic (7.70e-3)" "unprognostic (3.75e-2)" "unprognostic (9.27e-3)" "prognostic unfavorable (5.45e-4)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (9.18e-3)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (7.24e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (6.19e-10)" "unprognostic (6.72e-3)" "unprognostic (3.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.68e-2)" 74.3 26.7 23.0 74.5 27.2 50.3 58.2 18.8 39.8 183.7 30.2 570.3 31.5 489.5 28.8 64.5 236.0 45.0 79.9 22.3 27.6 52.8 16.0 84.7 15.1 23.9 23.4 94.2 15.1 9.6 66.3 33.2 24.9 245.3 24.9 5.7 42.3 200.7 661.5 38.0 111.7 177.6 20.8 84.5 156.1 37.6 28.5 11.5 37.1 70.5 7.6 315.4 125.0 20.5 115.8 25.8 120.7 89.4 32.5 59.9 118.9 232.4 132.8 128.9 89.0 50.9 109.6 20.4 220.4 156.4 69.5 59.5 19.7 160.6 30.3 27.5 27.6 73.6 92.2 52.6 83.6 38.8 237.3 132.0 29.1 115.6 51.5 191.9 85.4 18.3 52.4 15.3 102.5 103.9 7.0 88.6 75.7 23.2 108.8 144.4 101.3 14.0 89.1 29.6 17.5 35.8 91.5 16.9 44.6 39.9 24.3 31.3 292.9 153.8 168.1 60.5 211.7 4.0 4.7 24.1 73.3 44.2 35.7 177.1 46.7 121.2 5.3 22.9 6.3 9.6 3.1 7.2 26.7 5.3 3.0 4.0 438.7 2.3 29.3 1.9 7.0 23.9 23.0 27.2 18.8 39.8 22.3 27.6 23.9 23.4 24.9 20.8 28.5 20.5 36.6 0.0 0.6 11.1 7.5 14.5 47.1 106.8 6.2 6.3 7.6 65.3 21.0 4.3 20.9 25.8 14.6 12.5 4.4 5.5 25.4 164.8 27.0 7.5 44.8 51.0 3.5 9.4 13.9 242.1 53.3 65.0 9.7 7.3 17.2 18.6 51.0 1.6 64.0 8.4 7.4 2.1 36.7 16.6 18.3 49.3 44.7 44.9 10.6 5.6 31.0 16.2 1.0 2.0 1.7 320.1 33.6 223.0 3.2 30.4 1.0 15.7 13.2 22.6 164.3 24.6 157.7 11.6 38.7 12.2 15.8 14.1 10.8 18.2 3.1 25.3 PDXDC1 KIAA0251 ENSG00000179889 "Pyridoxal dependent decarboxylase domain containing 1" Q6P996 16 14974591-15139339 "Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 483.6;Late spermatids: 733.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047369, HPA049121, HPA051484" Approved Enhanced "Golgi apparatus,Vesicles" NA NA 9600 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus, Vesicles" "HPA047369: AB_2680015, HPA049121: AB_2680641, HPA051484: AB_2681502" "unprognostic (3.67e-2)" "unprognostic (4.99e-1)" "unprognostic (1.97e-3)" "unprognostic (1.84e-1)" "unprognostic (9.08e-2)" "unprognostic (2.18e-1)" "unprognostic (6.47e-3)" "unprognostic (4.97e-2)" "unprognostic (2.43e-1)" "unprognostic (2.74e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "prognostic favorable (3.13e-4)" "unprognostic (4.58e-2)" "unprognostic (8.11e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 33.3 37.9 4.9 20.9 5.0 12.9 33.1 14.7 6.5 35.7 7.9 61.3 52.5 31.9 17.0 43.4 29.2 20.8 39.1 6.0 4.1 47.6 104.5 34.6 13.4 6.2 4.7 31.1 70.4 27.1 63.2 23.5 7.5 55.8 47.8 13.4 80.5 25.2 52.0 27.8 61.1 18.5 1.2 31.8 56.7 113.2 7.2 11.7 42.9 16.5 15.0 39.1 34.7 5.7 21.4 30.9 31.1 26.1 16.9 20.4 51.4 19.6 17.4 14.3 19.7 38.0 45.3 40.7 42.0 26.5 20.5 34.0 22.1 20.1 20.5 25.0 30.2 24.7 51.8 100.2 44.3 19.7 56.4 21.5 20.4 25.0 20.9 28.0 15.3 21.6 18.5 26.0 34.1 52.2 12.9 10.4 15.3 20.8 11.7 19.9 12.9 48.6 22.7 33.9 31.9 22.8 52.6 30.0 50.9 19.7 121.0 30.3 23.8 11.0 10.0 12.3 25.7 24.2 25.1 39.3 22.7 16.4 35.8 2.9 7.8 11.6 9.4 7.7 10.8 8.3 6.8 7.7 11.7 9.0 8.2 8.1 1.0 7.5 6.2 5.4 6.6 8.2 4.9 5.0 14.7 6.5 6.0 4.1 6.2 4.7 7.5 1.2 7.2 5.7 29.6 38.5 64.6 32.7 33.0 38.2 42.2 21.6 18.8 32.1 57.9 27.8 45.7 58.6 52.9 29.5 31.3 51.7 30.6 149.8 27.4 38.2 483.6 48.1 41.7 35.1 161.2 33.2 80.7 58.3 56.5 36.0 71.9 75.3 39.3 42.1 27.5 123.6 30.5 40.4 68.3 216.7 24.4 33.1 16.8 733.8 49.0 30.9 26.6 31.9 27.5 19.7 39.1 55.8 45.0 46.5 114.4 45.5 45.4 58.1 115.6 53.4 48.3 47.4 46.0 24.0 28.0 142.3 72.7 24.6 42.6 80.7 33.9 21.2 127.2 76.5 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.9;seminal vesicle: 17.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 371.6;Inhibitory neurons: 125.6;Oligodendrocyte precursor cells: 561.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-266/70: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042101: AB_2732496" "unprognostic (6.74e-2)" "unprognostic (6.86e-2)" "unprognostic (3.82e-2)" "unprognostic (2.88e-2)" "unprognostic (1.49e-1)" "unprognostic (5.34e-2)" "unprognostic (2.48e-2)" "unprognostic (1.38e-2)" "unprognostic (8.19e-2)" "unprognostic (7.85e-3)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-3)" "unprognostic (1.80e-1)" "unprognostic (7.33e-2)" "unprognostic (1.41e-3)" 1.2 0.9 1.5 1.1 2.5 0.0 1.9 0.1 2.3 2.2 0.0 10.9 0.8 0.9 2.2 3.8 2.2 1.7 0.4 1.5 0.9 0.5 0.6 0.3 0.0 1.3 3.3 1.9 0.4 0.1 0.4 4.0 2.2 6.6 3.1 1.0 0.3 17.8 0.3 0.5 2.9 2.5 1.3 0.2 3.3 2.4 1.4 0.0 0.3 1.9 0.3 3.9 2.6 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 0.1 2.3 1.5 0.9 1.3 3.3 2.2 1.3 1.4 1.9 0.1 0.0 0.0 37.5 0.3 0.8 0.0 0.0 2.8 9.8 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.3 0.0 0.0 371.6 0.0 0.2 17.3 1.1 0.0 0.0 19.8 1.4 0.0 0.4 0.0 125.6 0.0 0.0 0.0 0.3 1.6 28.0 0.2 0.0 5.6 0.0 0.4 0.0 561.9 13.7 0.0 0.0 56.4 1.2 0.1 0.0 0.0 0.7 1.1 0.0 0.1 5.7 0.1 0.2 0.8 0.6 0.4 0.0 34.1 0.0 0.1 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Excitatory neurons: 162.1;Oligodendrocyte precursor cells: 513.2;Oligodendrocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.8" "Cell line enhanced" "Detected in all" "TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 13.8 4.4 8.9 5.8 13.3 9.1 9.5 5.5 8.8 11.3 1.0 7.8 5.9 7.4 6.4 5.2 5.7 10.0 16.2 8.2 8.4 5.0 3.8 18.0 6.8 6.4 7.8 7.5 4.8 5.4 2.9 16.7 5.8 6.0 8.1 13.7 5.5 7.3 6.7 6.7 7.3 9.9 4.9 29.4 4.9 9.9 11.8 4.7 6.3 8.5 4.7 9.0 7.5 11.7 5.4 7.8 18.1 4.3 33.4 35.7 6.3 28.6 19.7 14.9 14.9 6.3 4.7 4.1 5.0 41.4 5.7 2.6 14.6 4.5 16.9 4.2 7.6 7.7 12.2 3.8 12.2 4.6 3.9 27.6 4.3 28.8 4.8 16.3 42.3 6.6 10.0 4.0 16.1 2.2 2.6 4.9 8.4 3.7 2.1 5.3 10.8 3.0 4.4 9.6 4.0 4.9 11.2 2.3 18.6 19.7 1.7 3.2 52.1 31.5 15.2 13.2 12.2 6.3 9.5 5.9 5.5 10.5 17.3 0.1 0.2 0.4 0.2 0.0 0.4 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 1.8 0.1 0.2 0.0 0.2 8.9 13.3 5.5 8.8 8.2 8.4 6.4 7.8 5.8 4.9 11.8 11.7 48.3 147.4 46.8 101.9 12.6 21.9 7.5 5.6 2.2 18.4 6.1 5.8 46.9 10.0 29.2 1.8 12.5 3.1 12.3 23.9 0.0 6.9 15.1 22.9 19.5 41.2 3.0 10.8 162.1 5.4 2.0 35.6 15.8 10.1 17.7 6.3 31.8 6.0 18.9 20.2 84.4 11.9 2.0 21.3 34.7 13.6 19.9 20.2 12.4 124.6 8.5 28.1 10.3 513.2 338.1 9.8 10.7 16.1 7.0 8.3 15.7 3.7 41.6 20.1 13.1 23.0 37.7 13.6 13.7 5.8 18.0 6.3 8.2 22.6 12.3 7.2 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PERCC1 ENSG00000284395 "Proline and glutamate rich with coiled coil 1" A0A1W2PR82 16 1431078-1434441 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "prostate: 1.8;stomach 1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 56 "SCLC-21H: 33.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 4.0" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 7: SCLC-21H - Neuronal signaling" 0.1 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.6 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 33.3 0.4 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3312.8;Squamous epithelial cells: 3451.4;Suprabasal keratinocytes: 5828.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in many" "hTCEpi: 1024.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" 27.1 9.3 7.0 9.9 7.1 1.5 131.0 7.8 8.6 201.6 13.7 40.9 50.2 23.2 47.9 782.9 61.2 37.9 53.9 6.8 8.1 21.9 93.7 27.0 3.3 9.2 7.8 6.4 33.1 40.6 13.1 38.7 8.6 60.7 38.4 8.7 295.9 46.8 5.7 1115.1 52.0 19.8 7.8 1.4 65.1 3.1 9.3 23.3 24.6 16.3 149.4 60.2 426.4 6.3 81.5 80.3 3.7 11.3 60.0 63.1 172.7 115.5 129.8 17.6 12.9 64.8 143.1 1.5 45.5 37.5 144.0 268.4 15.6 207.6 4.5 126.9 64.6 1.5 70.7 69.8 42.6 1.7 1.0 44.3 1024.8 2.2 111.8 91.7 71.3 5.8 2.4 31.3 3.0 53.4 1.5 4.6 34.4 174.6 47.1 1.5 28.6 0.9 108.2 94.0 29.3 3.7 141.2 68.7 59.6 90.7 36.4 18.4 82.6 29.4 12.1 31.7 2.1 11.1 17.4 1.3 23.0 1.5 65.5 39.8 0.0 0.0 4.3 0.0 7.6 2.0 5.3 3.8 0.0 1.0 0.6 2.3 0.3 0.1 0.0 0.0 8.9 1.3 7.0 7.1 7.8 8.6 6.8 8.1 9.2 7.8 8.6 7.8 9.3 6.3 13.9 211.5 84.2 0.7 8.1 3312.8 1415.8 1383.2 1110.4 3.3 371.4 305.0 137.7 260.2 728.5 154.5 16.7 994.5 17.6 374.8 62.6 588.0 2.1 1013.4 78.1 71.8 147.2 13.9 1.2 305.1 990.1 83.8 197.2 777.1 10.8 0.5 21.4 171.3 82.0 3.3 2.1 185.0 736.5 3.8 259.2 2.7 10.5 12.8 350.4 12.2 10.3 29.1 3.1 2.0 0.5 655.0 316.7 2.6 43.2 789.2 355.0 10.6 743.5 28.3 6.6 15.4 82.6 2.4 1.4 3451.4 5828.3 824.0 67.2 73.5 218.6 1546.6 PEX11G ENSG00000104883 "Peroxisomal biogenesis factor 11 gamma" Q96HA9 19 7476875-7497449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.4;testis: 29.0" "Cell type enhanced" "Detected in many" "Early spermatids: 85.3;Late spermatids: 69.6;Proximal enterocytes: 37.0;Proximal tubular cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA069817 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "HPA069817: AB_2686207" "unprognostic (2.26e-2)" "unprognostic (6.44e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.60e-4)" "unprognostic (1.01e-1)" "unprognostic (4.09e-3)" "prognostic favorable (3.27e-4)" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" "unprognostic (2.32e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.83e-9)" "unprognostic (1.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.19e-2)" 4.6 12.1 2.9 1.4 4.7 1.2 5.3 3.3 3.5 3.7 2.4 5.1 6.5 2.9 2.3 4.9 3.6 1.6 2.5 2.9 3.2 8.5 26.4 3.4 1.0 3.7 3.9 3.3 5.4 4.0 4.3 0.9 3.5 6.4 1.5 1.1 4.8 1.9 2.1 5.9 5.7 0.7 3.4 5.0 5.0 29.0 3.5 1.0 6.4 0.9 0.4 4.3 3.6 4.9 1.9 3.6 0.8 3.2 2.5 1.4 4.7 1.0 0.7 0.8 0.8 1.3 6.3 1.1 5.9 0.5 1.4 3.3 0.6 1.1 0.3 0.5 1.3 0.7 1.0 0.3 2.2 0.1 3.7 2.9 1.3 0.8 1.1 0.6 0.5 3.1 1.7 0.1 1.0 1.0 0.6 0.7 0.2 3.0 2.1 0.1 0.2 0.1 2.2 2.4 2.3 2.1 1.6 0.3 0.5 0.5 5.2 1.2 0.0 0.1 0.5 3.1 0.1 1.9 1.3 0.6 0.5 0.1 0.6 24.5 3.9 16.0 1.6 3.9 1.1 2.5 1.1 0.6 3.5 4.1 1.2 0.9 12.8 7.9 3.5 2.3 0.4 2.4 2.9 4.7 3.3 3.5 2.9 3.2 3.7 3.9 3.5 3.4 3.5 4.9 3.8 0.0 9.2 2.3 1.0 3.2 4.3 15.9 5.2 2.6 10.2 9.4 2.1 7.2 8.1 3.7 2.1 3.0 0.4 12.6 17.6 9.3 85.3 16.5 4.2 3.7 5.4 0.4 0.6 3.6 3.1 5.2 7.7 6.9 0.0 7.6 4.6 35.9 18.1 0.0 0.9 11.4 16.2 7.5 0.4 69.6 4.4 3.5 3.6 1.0 1.8 7.0 0.0 1.5 3.6 4.5 9.6 3.8 0.9 3.2 37.0 41.5 29.3 3.2 6.6 3.2 4.0 22.4 3.1 5.8 2.7 1.4 1.1 11.6 11.3 3.8 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 277.0" "Cell type enhanced" "Detected in many" "Early spermatids: 459.8;Late spermatids: 516.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1900000 "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018257: AB_10960391, HPA056484: AB_2683147" "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.55e-4)" "prognostic unfavorable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 35.0 11.5 41.6 41.5 39.3 14.4 23.5 13.8 49.9 26.3 61.7 43.8 48.8 55.5 5.6 67.1 34.9 34.1 128.6 60.4 65.0 44.6 4.7 19.1 32.5 30.7 50.9 19.1 15.9 15.2 29.9 15.5 58.0 35.6 30.7 277.0 39.8 62.0 70.4 40.3 59.6 44.1 8.3 19.1 36.8 141.1 47.0 29.7 38.5 21.0 21.2 64.7 42.8 31.7 314.8 420.2 25.9 0.6 26.8 56.9 336.9 187.2 66.6 186.2 222.8 444.5 320.4 37.0 147.8 134.9 174.9 243.0 141.7 292.3 173.1 102.1 111.0 132.0 189.1 24.2 65.2 53.7 203.4 27.0 61.2 190.0 96.0 273.7 367.8 153.7 37.0 1.3 195.7 239.8 182.5 44.4 42.9 133.9 149.3 138.8 46.9 150.1 185.7 115.9 69.5 64.7 133.7 111.0 172.0 307.8 93.7 80.3 449.2 124.6 65.3 380.5 199.3 195.4 200.1 135.7 331.0 98.0 78.5 30.8 8.5 2.9 26.8 4.2 21.2 13.7 26.2 25.0 14.5 15.3 9.6 15.4 1.3 26.7 1.6 22.5 37.6 16.5 41.6 39.3 13.8 49.9 60.4 65.0 30.7 50.9 58.0 8.3 47.0 31.7 30.5 3.2 7.0 128.6 14.8 28.7 58.5 96.8 14.8 40.4 10.3 7.7 147.4 8.6 57.9 64.4 54.2 7.8 16.3 72.6 43.0 115.7 459.8 41.2 9.0 36.0 37.2 10.3 49.4 10.8 205.8 25.9 35.7 63.8 55.9 25.8 14.6 0.7 33.9 42.1 25.9 23.1 124.1 7.6 31.4 516.3 7.5 14.3 19.6 15.0 15.4 113.1 16.5 16.1 6.7 116.8 57.2 6.8 14.2 80.9 53.2 5.9 62.6 133.4 13.1 43.2 34.6 149.4 3.5 25.1 22.6 26.5 28.8 11.2 28.9 64.2 PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 5241.0;monocytes: 4824.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" 573.1 365.8 278.0 1133.4 302.0 1613.0 397.0 323.2 333.0 393.7 289.2 970.2 764.0 734.4 346.4 582.7 500.9 372.7 343.8 281.8 301.5 460.9 661.6 559.2 1357.9 347.3 325.4 247.7 246.4 311.3 198.9 581.1 348.6 419.4 808.4 71.8 346.9 601.4 337.9 449.8 772.9 1034.7 315.2 910.8 675.1 116.2 366.2 1197.6 269.2 238.7 1440.0 842.6 425.0 355.2 3019.5 4276.8 1461.5 1205.2 778.8 977.1 1972.7 2416.8 1970.4 2568.6 1923.7 1684.1 1181.1 2476.9 1892.0 2542.0 1453.6 1825.4 1383.6 3040.5 2049.6 3560.1 2355.1 2516.6 2034.3 2225.8 2144.0 1630.4 5006.0 1152.4 1331.9 1957.6 1939.8 1477.6 2361.3 1646.4 1488.6 1736.7 3150.5 1815.0 2469.9 3448.0 2095.2 1474.7 2297.3 2451.9 2035.1 1494.6 2491.7 1909.8 564.0 1586.2 1910.5 1180.9 1679.7 1226.8 1121.0 1359.7 2731.7 2136.6 1675.1 1512.3 3969.3 931.3 1070.7 1799.3 1834.4 1949.7 3316.4 8100.1 8206.3 13914.4 9850.0 10858.8 6780.3 5722.0 8185.7 9586.6 9920.0 4970.0 5238.0 7604.7 9387.0 9112.1 13547.4 7809.7 11245.6 23570.1 278.0 302.0 323.2 333.0 281.8 301.5 347.3 325.4 348.6 315.2 366.2 355.2 561.8 112.2 176.1 12.1 1070.6 1806.0 873.2 3658.3 1003.3 25.0 767.4 914.1 147.6 457.5 1020.0 741.2 0.0 1911.0 1725.6 1733.8 992.0 1866.6 19.7 313.4 546.1 806.6 603.7 713.5 7.1 1625.2 5241.0 599.9 733.4 422.7 486.5 291.2 637.5 754.3 4094.2 38.7 6.4 1399.7 1452.6 1434.3 2934.8 31.0 263.8 1854.7 873.4 21.5 4824.7 99.8 3216.3 9.0 37.2 2933.5 1585.7 375.0 927.8 1238.2 1472.2 1671.2 559.4 17.8 506.2 282.3 1838.4 97.4 355.4 1170.1 1513.5 1682.8 1804.7 410.7 1355.5 1177.9 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavorable (8.78e-4)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 23.6 21.0 12.0 18.1 12.9 9.3 18.0 20.2 15.2 24.4 19.6 18.0 15.8 17.1 34.5 12.3 13.4 24.6 14.3 9.7 10.5 13.6 38.3 16.8 11.2 10.9 10.2 22.7 46.1 13.3 28.2 47.5 13.1 51.0 23.4 26.8 35.8 20.3 6.7 10.9 18.2 18.5 6.6 11.5 24.9 32.3 11.1 8.2 25.6 8.6 15.2 19.0 12.3 15.9 35.1 23.4 41.8 51.0 68.9 72.9 48.9 118.1 82.9 55.2 83.3 60.1 16.1 18.3 24.7 112.3 53.0 20.1 38.4 49.5 104.6 14.6 37.8 22.7 41.9 105.0 77.6 22.6 11.2 46.2 40.1 96.6 120.0 55.5 64.6 12.1 74.9 19.6 61.0 39.1 3.7 14.7 18.8 31.8 31.6 16.2 92.5 11.3 42.0 36.0 16.9 26.3 34.8 28.5 20.9 61.8 27.0 25.5 94.2 38.3 21.2 74.9 60.5 36.5 16.1 13.0 29.7 17.7 58.4 10.8 4.1 2.7 2.6 3.5 3.9 4.6 2.8 3.4 3.6 2.5 4.5 4.7 1.8 3.5 4.5 4.2 2.1 2.3 12.0 12.9 20.2 15.2 9.7 10.5 10.9 10.2 13.1 6.6 11.1 15.9 14.3 28.9 27.7 14.4 13.0 15.8 29.2 28.5 5.7 16.4 19.9 15.0 6.8 15.7 36.1 11.0 10.4 32.4 12.7 15.9 7.9 31.7 67.7 17.0 35.1 13.8 16.1 6.9 25.1 49.6 71.1 46.1 23.9 36.4 5.1 25.4 14.3 32.6 17.6 8.4 29.4 35.5 18.3 6.0 8.7 20.9 33.5 8.6 10.6 15.9 10.1 25.9 2.1 41.2 36.8 37.9 19.7 18.4 44.1 56.5 16.1 23.2 22.2 21.1 6.6 22.1 26.6 75.5 34.2 11.6 15.6 64.4 10.1 12.2 17.6 25.6 PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell adhesion, Glucose metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.2;Endothelial cells: 36.6;Hepatic stellate cells: 39.3;Microglial cells: 124.6;Sertoli cells: 52.6;Smooth muscle cells: 35.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Group enriched" "Detected in some" 5 "hTERT-RPE1: 28.7;PC-3: 56.5;RH-30: 38.8;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" 28.9 61.0 3.7 12.6 4.1 0.0 21.0 5.8 3.8 51.7 3.3 269.4 15.4 154.0 40.8 98.6 96.5 19.6 126.1 3.1 4.1 11.5 5.1 14.6 5.8 4.6 4.0 19.8 2.7 5.0 4.3 5.8 4.3 159.0 34.2 8.0 6.7 214.0 37.5 11.1 72.0 132.5 4.7 10.8 65.2 3.0 4.6 2.9 13.1 30.5 2.9 216.7 40.6 4.6 0.2 0.2 0.0 0.0 0.7 0.0 0.3 8.2 6.3 3.8 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 9.2 0.0 9.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 28.7 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.7 0.0 0.0 56.5 0.0 38.8 1.8 1.5 0.0 0.0 0.2 0.1 47.8 2.8 1.2 0.0 0.0 0.1 0.0 5.7 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 3.7 4.1 5.8 3.8 3.1 4.1 4.6 4.0 4.3 4.7 4.6 4.6 21.6 0.0 1.7 0.7 0.2 2.3 5.6 0.0 0.6 25.3 0.2 1.5 107.2 2.8 1.8 12.9 4.2 0.0 0.1 0.1 1.9 0.1 1.8 3.7 2.8 36.6 0.0 4.0 1.4 0.0 0.2 12.4 0.0 1.1 0.0 18.7 39.3 0.1 0.1 0.0 1.7 2.7 0.0 4.0 2.8 0.5 8.1 2.1 3.6 124.6 1.0 8.3 0.0 1.0 2.3 0.1 0.1 4.9 0.0 2.1 0.8 1.2 0.8 1.9 52.6 1.7 35.9 0.1 0.2 0.4 2.4 0.0 0.6 30.0 1.6 1.5 PHF21B "BHC80L, FLJ34161, PHF4" ENSG00000056487 "PHD finger protein 21B" Q96EK2 22 44881162-45010005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.9" "Cell type enhanced" "Detected in some" "Astrocytes: 96.6;Cone photoreceptor cells: 22.9;Horizontal cells: 28.6;Late spermatids: 41.9;Oligodendrocyte precursor cells: 29.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 11.2;AN3-CA: 10.0;JURKAT: 8.8;SCLC-21H: 8.7;SH-SY5Y: 37.5;U-2 OS: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053834, HPA074665" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA053834: AB_2682276, HPA074665: " "unprognostic (1.04e-1)" "unprognostic (7.76e-2)" "unprognostic (2.00e-1)" "unprognostic (7.44e-2)" "unprognostic (1.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (1.86e-3)" "unprognostic (2.02e-1)" "unprognostic (9.35e-2)" "unprognostic (2.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.22e-1)" 0.2 1.2 6.7 0.1 7.9 0.0 0.4 4.8 6.1 9.0 1.5 0.2 0.1 3.2 0.4 0.4 2.5 0.1 0.9 5.1 5.1 2.6 0.0 0.1 0.0 8.5 8.3 4.0 0.5 0.9 18.9 0.0 5.2 5.2 0.0 6.1 0.3 0.5 0.2 0.1 0.2 0.7 4.4 0.1 0.6 5.4 6.8 0.2 2.0 0.3 0.0 0.2 3.2 4.7 0.0 0.0 11.2 10.0 0.0 0.0 0.7 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.1 2.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.6 0.0 0.0 8.8 0.0 0.0 0.1 0.9 1.3 0.0 6.7 0.0 0.4 0.0 2.6 0.2 0.0 0.1 8.7 37.5 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.5 8.5 0.0 0.2 0.4 0.0 5.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 7.9 4.8 6.1 5.1 5.1 8.5 8.3 5.2 4.4 6.8 4.7 0.0 0.0 0.0 96.6 0.0 0.1 0.6 0.0 0.0 14.1 0.0 0.3 2.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 1.9 0.0 16.2 0.1 3.2 0.4 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.0 0.0 0.1 28.6 9.1 0.0 0.0 0.0 0.0 41.9 0.6 0.1 0.0 5.6 0.0 5.0 0.0 29.1 9.3 0.1 0.0 1.9 0.0 1.7 0.0 0.0 0.7 23.3 0.0 1.1 0.5 1.2 2.9 0.0 0.0 0.0 0.3 1.9 0.0 0.1 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 158.7;Spermatocytes: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA034726: AB_10602191, HPA034727: AB_2674302" "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favorable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 5.0 2.8 1.9 2.4 1.9 2.9 10.6 4.1 1.6 4.7 3.7 5.8 6.4 5.3 4.2 3.2 6.0 4.0 2.7 1.6 2.8 5.6 3.6 3.3 3.0 1.4 1.8 6.0 5.1 7.2 4.6 3.0 1.5 13.0 5.8 7.2 8.5 4.7 3.4 3.5 6.4 3.1 1.7 2.5 4.7 13.7 2.4 3.0 9.8 1.6 3.0 3.8 2.8 1.9 6.6 1.8 4.6 6.2 8.5 2.7 17.8 2.8 1.9 4.3 4.7 6.3 4.9 6.4 6.1 2.1 8.9 5.0 6.2 3.4 3.5 9.5 7.0 6.4 6.1 11.0 5.6 5.3 5.6 4.9 6.3 4.9 6.5 3.6 3.9 8.9 10.8 6.4 2.7 6.0 3.7 6.8 6.0 4.2 2.3 3.6 2.8 5.1 6.8 19.6 19.1 6.5 5.8 3.1 6.8 5.5 8.4 3.2 2.3 4.7 4.3 4.2 3.1 6.2 6.0 5.7 5.5 3.2 5.1 0.1 0.7 1.0 3.3 0.9 4.6 6.5 3.6 3.2 0.9 8.8 4.7 4.6 1.3 9.8 0.9 4.2 4.4 1.4 1.9 1.9 4.1 1.6 1.6 2.8 1.4 1.8 1.5 1.7 2.4 1.9 6.1 3.2 3.6 0.0 6.8 2.5 10.3 5.4 2.8 8.7 15.2 11.0 4.1 5.7 4.7 3.7 6.2 8.8 2.5 7.0 9.8 7.6 158.7 10.6 5.0 4.3 15.0 6.9 0.0 11.1 9.3 6.9 15.3 3.3 0.0 5.7 2.5 3.7 2.8 6.7 0.0 6.6 12.2 0.6 1.6 35.9 4.7 2.0 3.6 0.0 1.0 6.4 1.0 0.0 0.0 6.4 6.8 4.9 3.8 6.5 12.7 12.2 13.4 10.2 0.0 6.7 9.3 68.9 13.9 4.5 4.3 5.5 5.7 8.8 7.5 5.5 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600286 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autism spectrum disorder, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA031624: AB_10601046" "unprognostic (1.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (3.47e-2)" "unprognostic (8.25e-3)" "unprognostic (8.69e-3)" "unprognostic (3.26e-3)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (6.17e-3)" "unprognostic (1.39e-1)" "prognostic favorable (2.68e-7)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (7.00e-2)" "unprognostic (3.73e-1)" 15.4 34.2 19.9 8.2 23.6 27.2 19.2 23.4 26.4 25.9 22.5 14.2 12.6 14.0 36.6 14.0 15.5 13.6 15.1 19.4 23.4 34.7 23.9 13.7 11.9 23.9 22.4 23.8 29.2 66.7 13.6 12.5 23.9 28.9 11.6 47.6 26.2 16.0 32.2 19.9 16.1 10.9 22.6 16.5 19.6 20.7 22.7 11.8 28.8 24.7 13.3 16.4 14.4 27.4 24.5 15.6 14.7 30.3 32.1 12.3 12.4 13.3 16.1 18.2 17.7 25.4 8.3 16.5 12.9 9.1 30.4 17.5 26.3 18.9 20.1 25.4 34.8 17.3 12.4 26.1 25.2 12.8 19.9 17.9 23.8 13.7 21.0 5.6 11.8 28.5 39.7 11.5 13.3 21.4 18.8 21.4 2.7 33.8 41.9 6.3 14.8 9.9 19.6 20.0 18.3 22.1 10.1 19.4 33.8 10.8 22.0 12.5 6.1 18.1 23.2 23.8 15.8 21.9 15.2 11.2 13.9 27.1 25.7 42.0 24.8 52.5 44.9 35.1 58.5 61.8 46.5 41.8 25.4 72.0 48.3 45.0 12.1 51.5 45.7 29.6 48.2 35.0 19.9 23.6 23.4 26.4 19.4 23.4 23.9 22.4 23.9 22.6 22.7 27.4 14.8 3.2 14.1 5.5 23.6 20.6 20.4 37.1 19.4 35.5 22.8 25.9 4.9 22.8 17.8 22.0 35.5 29.8 28.7 9.5 29.4 22.3 12.1 20.3 10.5 16.1 7.2 13.2 8.0 37.1 28.7 20.8 9.2 10.9 7.0 13.4 13.9 14.6 22.7 26.9 10.4 14.9 26.4 7.6 12.9 9.4 21.5 12.3 35.6 7.5 7.0 96.6 23.7 8.5 10.3 24.3 10.6 21.1 31.2 26.8 29.4 31.3 12.2 45.5 0.0 22.7 18.7 78.8 59.5 17.7 20.9 56.4 20.7 34.6 14.1 18.2 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700468 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Phagocytosis" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "U-2197: 75.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Approved Nucleoplasm,Cytosol No No "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017168: AB_1855395" "unprognostic (1.20e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.36e-3)" "prognostic favorable (7.28e-5)" "unprognostic (7.03e-2)" "unprognostic (4.02e-3)" "unprognostic (5.80e-3)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-3)" "prognostic favorable (2.32e-4)" "unprognostic (1.51e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" 22.1 15.6 30.7 11.5 36.6 3.4 19.2 19.4 66.4 24.0 0.0 62.2 8.6 44.9 7.6 20.3 29.8 8.2 32.2 40.2 5.0 15.8 8.7 22.6 6.5 13.3 7.7 22.2 18.0 10.7 20.6 11.2 12.9 33.9 4.5 13.2 18.1 25.1 17.7 16.0 24.1 16.0 0.0 22.4 29.7 61.4 19.5 5.3 21.1 4.8 4.2 39.4 24.7 33.2 18.9 18.0 13.4 18.0 25.5 21.0 20.3 36.1 22.4 15.2 12.3 16.1 5.2 7.8 13.6 39.0 16.5 16.4 6.5 11.7 6.2 28.7 11.9 9.0 15.0 13.1 22.0 9.4 26.7 23.7 9.9 12.4 4.1 9.9 25.6 11.5 14.1 13.5 14.4 15.7 11.2 6.6 14.4 6.8 24.6 21.4 7.2 11.2 11.5 15.9 13.7 12.0 18.7 10.1 11.1 16.6 7.9 14.1 57.3 21.3 11.8 75.1 17.0 16.0 14.3 3.5 27.6 19.2 15.0 1.0 0.7 0.0 0.7 0.5 0.2 0.6 0.5 0.4 0.8 0.3 0.2 0.4 0.5 0.5 0.8 0.5 0.4 0.6 30.7 36.6 19.4 66.4 40.2 5.0 13.3 7.7 12.9 0.0 19.5 33.2 20.3 6.4 5.0 8.8 6.2 5.4 3.0 6.1 7.4 56.8 9.6 6.6 7.5 7.2 3.0 16.5 37.5 7.8 10.6 12.2 1.9 7.9 11.6 6.4 29.0 22.1 8.4 2.1 30.6 7.1 7.4 10.7 7.1 11.6 1.3 10.7 16.1 4.0 15.7 30.3 17.9 9.7 6.1 19.6 13.2 24.0 14.9 15.5 5.4 22.5 15.0 14.3 11.3 9.0 6.8 12.1 13.2 24.0 5.7 4.4 7.2 6.4 4.1 26.8 13.1 8.4 10.4 18.6 11.8 7.8 6.8 16.4 8.0 11.9 7.2 5.3 PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 8.7;Spermatogonia: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 93.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Mitochondria" "HPA036587: AB_2732473, HPA036588: AB_10673502, HPA057508: AB_2683452" "unprognostic (1.43e-1)" "unprognostic (9.46e-2)" "unprognostic (2.59e-3)" "unprognostic (2.22e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-3)" "unprognostic (1.96e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-4)" "unprognostic (6.89e-2)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" 3.3 1.1 5.5 2.8 5.3 24.3 3.6 4.9 5.0 4.4 3.4 5.8 5.8 3.7 2.3 1.6 3.6 4.6 2.8 5.6 4.7 3.2 1.3 2.7 3.9 4.5 4.4 3.4 11.3 0.4 2.2 2.0 4.5 2.5 6.0 6.7 8.8 2.6 1.0 1.7 6.3 2.0 4.5 3.7 5.1 13.3 4.9 3.0 2.0 1.0 2.7 3.3 3.0 5.4 0.2 0.1 0.4 0.0 6.6 4.3 0.5 0.5 0.3 0.2 0.9 0.7 0.6 0.0 0.4 2.8 0.2 0.0 0.9 0.0 0.2 2.7 0.3 0.2 0.6 0.0 2.5 6.5 0.1 1.5 0.0 0.5 0.0 0.1 0.1 0.5 0.3 0.0 1.1 0.4 0.3 93.2 0.1 9.2 0.6 0.4 0.0 0.0 2.1 0.0 0.4 0.3 0.4 0.9 0.4 0.3 0.0 20.7 1.2 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 9.9 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 5.5 5.3 4.9 5.0 5.6 4.7 4.5 4.4 4.5 4.5 4.9 5.4 1.1 0.0 0.5 3.3 0.2 1.3 0.2 0.4 0.0 0.6 1.3 1.3 3.5 7.2 1.4 0.0 0.0 4.0 0.2 4.1 1.9 6.2 4.7 0.7 0.7 0.6 0.0 0.4 5.4 2.0 0.5 1.6 7.7 1.3 0.0 0.9 0.7 0.0 1.7 0.0 4.9 8.7 0.0 3.0 1.7 2.1 0.3 1.7 0.0 3.7 2.0 0.7 1.0 5.0 6.0 3.0 4.9 1.2 0.1 0.5 4.4 0.6 1.7 3.3 0.0 2.2 1.3 1.2 12.0 0.6 0.1 1.0 0.3 0.3 5.3 0.1 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 345.0;Extravillous trophoblasts: 176.8;Paneth cells: 248.9;Proximal enterocytes: 195.6;Undifferentiated cells: 142.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 151.3;CAPAN-2: 102.6;HaCaT: 199.1;hTCEpi: 126.9;MCF7: 94.9;SK-BR-3: 148.0" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" 1.1 0.1 0.3 3.7 0.2 0.0 9.1 0.2 0.6 50.2 0.1 34.3 31.1 1.4 4.7 294.4 7.5 4.9 0.8 0.3 0.3 4.2 0.8 9.7 0.1 0.6 0.2 0.3 27.4 9.1 15.8 10.9 0.6 19.8 10.2 0.0 52.8 5.0 1.0 223.0 28.6 0.5 0.2 0.2 29.1 0.7 0.3 2.5 12.8 0.1 8.8 9.2 104.3 0.3 151.3 28.8 0.0 0.6 0.1 0.2 60.3 1.2 1.0 3.1 1.6 59.2 102.6 0.1 6.0 1.1 6.4 199.1 0.0 75.1 0.5 0.1 36.9 0.1 18.0 41.7 0.6 0.0 0.3 0.5 126.9 0.5 30.8 0.5 0.5 0.0 45.3 0.9 0.4 94.9 0.5 0.2 0.3 75.6 49.1 0.8 0.3 0.6 1.6 29.9 41.1 0.7 42.7 148.0 0.2 1.8 53.8 0.4 5.4 1.0 5.2 2.7 0.8 0.2 0.4 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.6 0.3 0.3 0.6 0.2 0.6 0.2 0.3 0.3 0.2 16.0 13.0 0.0 1.1 72.1 52.0 56.1 54.7 0.2 27.7 26.5 1.1 11.5 36.8 12.9 0.0 133.8 0.4 345.0 0.0 83.8 0.0 16.1 1.8 1.8 21.7 0.0 0.2 62.9 176.8 2.3 91.3 27.4 13.4 0.4 0.0 0.3 13.2 0.0 0.0 95.1 36.7 0.3 6.5 0.4 0.9 0.9 1.8 0.0 2.0 0.6 0.0 0.0 0.0 140.2 248.9 0.0 0.2 63.5 195.6 0.9 17.9 0.2 0.0 0.0 2.8 0.2 1.7 114.1 88.7 109.7 1.6 0.0 142.9 60.4 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 78.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.5;Distal enterocytes: 21.7;Gastric mucus-secreting cells: 18.3;Glandular and luminal cells: 17.1;Suprabasal keratinocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 11.1;RT4: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.0 0.0 0.1 0.4 0.3 0.3 2.4 0.1 0.1 5.7 0.0 6.4 6.7 0.0 1.6 5.7 0.1 0.1 0.3 0.1 0.0 7.8 0.2 12.2 0.1 0.0 0.0 0.0 0.1 2.9 1.7 0.1 0.0 4.3 3.8 0.2 2.6 0.4 2.9 78.1 4.2 0.1 0.0 0.1 2.4 0.1 0.0 4.4 1.9 0.5 0.3 1.2 11.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 11.1 0.1 0.0 0.0 0.0 0.0 8.3 0.4 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 74.5 0.0 0.0 5.5 2.7 1.3 0.6 0.0 1.2 0.3 2.9 0.0 0.5 5.5 0.0 1.7 0.0 21.7 3.9 0.4 0.0 7.3 1.0 0.1 0.0 0.0 0.0 1.3 0.7 0.1 18.3 17.1 2.5 0.0 0.0 0.0 0.1 0.0 0.0 7.7 4.1 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 0.0 0.3 3.1 10.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 5.6 13.8 1.2 0.6 0.0 6.7 2.0 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 132.7;ovary: 47.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 75.3;Cone photoreceptor cells: 70.9;Leydig cells: 81.4;Peritubular cells: 73.4;Sertoli cells: 263.0;Smooth muscle cells: 63.1" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053361 Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 8.9 1.5 8.7 1.4 10.9 0.0 3.4 10.5 14.4 1.2 22.1 33.7 0.7 1.8 0.9 4.4 6.4 2.0 132.7 9.1 9.7 0.1 6.1 8.0 0.6 10.2 10.9 47.6 0.9 0.0 0.8 4.7 9.2 14.9 2.3 18.9 2.7 7.7 0.5 1.7 3.0 3.3 9.5 1.6 6.3 10.1 11.8 0.0 2.4 0.3 1.2 17.6 1.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 10.9 10.5 14.4 9.1 9.7 10.2 10.9 9.2 9.5 11.8 8.6 0.7 0.0 0.5 25.8 0.0 0.4 0.0 0.0 0.0 11.6 0.2 1.3 75.3 0.0 0.0 0.0 70.9 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.1 0.0 0.0 0.2 0.0 0.1 30.8 0.0 0.0 0.0 6.7 10.8 0.1 0.3 0.0 0.2 0.0 0.0 1.2 0.7 4.9 81.4 0.5 0.0 1.9 0.0 30.8 0.0 0.5 0.1 0.0 0.0 73.4 0.0 1.3 0.0 0.0 0.0 32.1 263.0 0.5 63.1 0.6 0.7 0.0 0.4 0.3 0.1 0.0 0.0 0.1 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Bipolar cells: 224.8;Muller glia cells: 221.7;Rod photoreceptor cells: 196.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 183.3;HMC-1: 84.2;REH: 75.1;U-698: 403.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 9.0 4.2 69.4 33.0 141.3 30.3 8.5 706.3 105.2 5.0 347.5 8.6 17.3 8.6 22.5 4.6 5.5 13.4 4.3 40.1 122.6 23.4 14.3 9.4 66.8 301.3 122.7 1.6 3.9 2.8 1.2 8.2 207.3 2.8 7.0 0.5 7.1 3.4 1.9 4.0 19.4 8.8 241.5 34.8 8.7 2.0 283.3 10.0 6.9 3.6 72.0 10.1 3.9 437.2 1.4 3.2 0.6 2.9 0.2 0.2 4.0 0.3 0.4 2.3 0.8 0.9 8.1 183.3 30.1 0.2 7.4 4.2 4.0 0.5 1.4 1.4 2.1 22.1 0.4 0.3 1.2 22.3 84.2 0.3 1.8 1.3 1.0 0.3 4.2 8.1 2.5 15.0 0.4 5.7 2.6 55.5 3.1 2.3 1.3 75.1 0.1 23.7 0.5 3.9 1.4 0.4 5.0 1.6 1.5 3.9 3.3 67.7 1.1 0.4 3.2 0.4 0.6 35.2 61.4 403.4 0.3 30.0 1.6 9.4 12.1 76.2 1.9 16.1 0.9 51.1 0.6 2.9 10.7 49.6 0.8 1.9 65.7 41.3 36.8 7.0 0.5 6.9 69.4 141.3 706.3 105.2 40.1 122.6 301.3 122.7 207.3 241.5 283.3 437.2 187.0 12.8 54.0 0.0 138.3 2.9 1.6 2.3 1.8 224.8 139.5 113.0 7.2 28.6 13.1 16.5 104.3 13.6 94.0 0.4 13.7 2.6 20.5 65.5 88.0 61.7 21.5 23.2 0.7 0.0 2.2 30.6 16.8 86.6 40.4 29.0 37.1 43.2 27.7 101.0 0.8 2.7 65.1 47.4 9.4 30.7 11.1 46.7 8.8 95.5 21.8 221.7 47.4 2.0 1.3 0.1 9.8 4.9 138.6 3.5 5.5 5.9 6.9 196.2 6.6 28.0 51.9 4.8 2.9 3.0 2.3 11.1 48.2 8.7 1.9 6.5 PLCL2 "KIAA1092, PLCE2" ENSG00000154822 "Phospholipase C like 2" Q9UPR0 3 16802651-17090604 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 27.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 212.5;Extravillous trophoblasts: 73.0;Inhibitory neurons: 163.7;Microglial cells: 124.6;Oligodendrocyte precursor cells: 121.7;Oligodendrocytes: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 21.1;Daudi: 24.7;HAP1: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047616, HPA061728" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA047616: AB_2680105, HPA061728: " "unprognostic (2.95e-2)" "unprognostic (8.09e-2)" "unprognostic (3.96e-2)" "unprognostic (6.35e-2)" "unprognostic (1.59e-1)" "unprognostic (3.83e-3)" "unprognostic (1.83e-1)" "unprognostic (9.31e-2)" "unprognostic (3.22e-2)" "unprognostic (8.72e-2)" "unprognostic (5.93e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.98e-10)" "unprognostic (2.01e-1)" "unprognostic (1.78e-1)" "unprognostic (2.70e-1)" "unprognostic (9.97e-2)" 7.8 11.8 2.8 5.8 5.0 10.0 5.9 13.7 4.0 4.2 1.1 5.6 6.6 6.6 2.5 1.3 4.3 4.1 21.1 3.3 1.6 7.4 5.6 4.8 10.2 3.6 1.7 12.5 6.7 0.8 6.0 3.8 4.1 3.1 5.7 2.1 2.8 1.4 27.1 1.9 8.3 4.2 0.8 12.9 5.4 3.9 1.7 5.9 3.7 7.7 7.7 2.6 3.1 2.9 0.0 1.9 2.5 0.0 9.3 21.1 2.0 1.8 5.0 0.8 2.0 0.0 1.8 24.7 0.0 1.6 1.0 0.0 24.8 0.9 1.8 11.8 5.2 0.0 2.6 0.0 0.3 3.8 2.7 3.4 0.2 6.9 0.0 1.5 4.3 8.1 5.8 9.4 0.0 0.0 4.3 0.4 5.0 0.0 2.6 9.4 0.0 13.5 0.0 0.4 8.0 3.6 1.0 3.0 0.7 1.7 0.0 4.0 4.4 1.2 1.7 1.1 4.2 8.9 0.0 15.7 1.3 5.2 0.9 0.9 0.8 1.9 2.1 0.9 2.6 1.4 2.0 2.9 1.0 1.3 1.9 2.1 1.8 6.5 1.2 0.5 1.5 1.1 2.8 5.0 13.7 4.0 3.3 1.6 3.6 1.7 4.1 0.8 1.7 2.9 8.6 0.0 2.2 8.1 17.5 1.0 0.9 1.1 1.2 11.5 0.6 0.4 38.6 11.5 1.1 3.7 4.2 2.5 34.1 12.5 7.9 2.6 1.1 7.5 4.1 6.6 3.6 7.0 212.5 9.2 73.0 7.8 17.3 2.1 2.5 5.6 5.7 6.4 7.8 16.8 163.7 9.8 0.0 8.7 4.6 1.5 19.6 13.8 0.0 124.6 12.3 1.2 39.1 121.7 72.2 2.9 22.6 19.2 18.2 0.5 9.5 10.9 1.3 1.8 6.6 9.6 5.0 2.5 5.4 0.3 0.6 49.8 24.2 6.5 5.4 0.6 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;brain: 16.7;lymphoid tissue: 11.3" "Cell type enriched" "Detected in many" 7 "dendritic cells: 284.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3621.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3621.6" "Group enriched" "Detected in some" 4 "HMC-1: 127.3;RPMI-8226: 85.5;THP-1: 191.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2900000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.4 1.0 5.1 5.7 4.7 13.4 1.5 7.0 7.1 1.0 0.4 0.8 3.8 1.0 0.2 0.6 1.8 2.4 0.5 4.5 7.3 0.8 0.5 1.8 11.3 15.7 6.8 0.5 1.1 1.2 2.1 0.8 10.3 1.7 0.5 0.5 3.5 1.8 0.3 0.6 5.1 0.5 13.9 10.4 2.8 0.6 9.4 2.8 0.6 0.0 9.4 1.9 0.4 16.7 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 127.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 10.7 0.1 0.0 0.1 30.0 0.1 85.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 191.5 0.0 0.1 0.3 0.1 0.2 0.4 0.0 0.1 0.2 1.6 0.3 4.6 43.0 699.5 1.0 188.4 1.9 222.7 0.8 1.2 545.8 198.4 1.7 0.4 9.8 25.4 297.9 3621.6 1.0 72.9 5.1 4.7 7.0 7.1 4.5 7.3 15.7 6.8 10.3 13.9 9.4 16.7 0.8 0.0 0.0 0.3 34.7 0.4 0.1 0.0 0.0 2.7 0.6 2.8 1.4 0.0 0.0 0.0 0.0 0.2 284.8 0.0 0.0 0.0 0.7 0.1 0.3 2.7 0.0 5.5 0.1 0.0 0.4 1.1 1.1 0.4 3.8 0.0 0.0 0.0 30.6 1.7 0.1 0.0 0.0 1.3 32.0 4.7 0.0 38.0 5.4 22.5 11.3 0.1 2.1 0.5 0.1 0.0 0.0 0.0 2.3 0.1 0.0 0.1 0.0 1.1 6.6 1.6 0.3 1.6 1.6 0.0 0.4 0.3 2.2 0.0 0.1 0.0 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Gastric mucus-secreting cells: 40.8;Microglial cells: 48.7;Oligodendrocytes: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 2.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 116.4;HaCaT: 75.2;OE19: 58.6;RT4: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: AB_10671746, HPA066103: AB_2732738" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (4.30e-2)" "unprognostic (2.51e-2)" "unprognostic (6.95e-3)" "unprognostic (2.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (3.13e-2)" "prognostic favorable (1.89e-15)" "unprognostic (9.74e-2)" "unprognostic (1.17e-2)" "unprognostic (4.81e-1)" "unprognostic (2.65e-2)" 10.3 1.7 10.0 5.5 11.9 0.6 13.3 9.6 7.0 11.2 26.5 18.3 27.3 4.1 3.8 46.0 9.1 7.3 24.0 7.5 14.3 26.4 16.7 8.0 2.3 11.5 17.9 12.7 15.2 17.6 4.2 9.0 11.8 7.0 16.9 27.4 21.5 5.3 2.2 14.1 25.4 3.6 7.3 1.8 23.7 10.1 21.2 4.0 10.9 2.2 6.6 14.0 18.3 10.3 14.2 12.7 11.9 5.5 0.7 0.0 20.7 0.1 0.4 4.9 9.0 22.6 116.4 0.2 5.4 1.9 0.7 75.2 16.9 0.2 3.5 4.2 16.2 39.7 11.2 13.5 0.3 0.1 0.5 0.6 6.4 0.0 0.4 10.7 0.0 14.3 1.7 0.4 2.0 8.7 8.8 0.3 6.1 58.6 12.4 11.5 0.0 3.0 10.9 109.9 8.3 0.9 16.7 44.3 0.6 22.3 11.3 4.1 3.3 0.2 4.1 3.2 2.8 7.6 2.4 16.2 0.1 0.8 0.1 0.1 0.1 3.7 0.3 0.0 2.0 0.1 0.3 0.2 0.1 0.0 0.1 0.2 0.3 0.1 0.0 0.4 0.0 0.2 10.0 11.9 9.6 7.0 7.5 14.3 11.5 17.9 11.8 7.3 21.2 10.3 8.2 3.2 17.0 111.0 0.6 0.6 1.1 1.4 0.6 2.3 6.9 6.1 8.7 7.2 8.6 11.0 25.0 6.7 0.2 12.0 3.9 6.1 16.3 20.5 2.3 4.7 0.0 1.3 19.3 6.0 0.9 1.0 40.8 22.9 2.5 16.1 2.2 2.9 1.8 0.0 26.2 6.5 0.0 1.0 1.4 6.1 0.6 2.7 0.0 48.7 0.8 4.3 1.0 15.6 37.9 10.7 4.1 0.4 1.8 0.8 9.2 10.6 8.0 9.7 0.0 1.0 1.2 0.5 0.5 12.3 0.4 6.0 1.2 2.1 3.1 6.4 PLEKHB2 "EVT2, FLJ20783" ENSG00000115762 "Pleckstrin homology domain containing B2" Q96CS7 2 131104847-131353709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075014 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA075014: AB_2732275" "unprognostic (1.99e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "unprognostic (8.78e-2)" "unprognostic (5.18e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (9.33e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.72e-8)" "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.14e-2)" "unprognostic (2.65e-1)" 27.0 55.5 52.7 38.3 55.4 64.8 26.1 61.4 56.2 25.4 53.4 59.9 46.8 16.6 30.7 30.3 26.7 29.7 33.5 57.8 73.1 111.8 22.4 44.4 37.0 64.8 69.4 11.7 20.8 88.5 26.2 31.0 81.3 34.6 60.9 81.1 26.0 26.3 35.6 23.5 56.2 25.9 56.8 42.5 58.5 36.1 60.0 31.2 48.7 30.6 34.5 38.3 18.2 63.1 85.3 65.4 48.6 38.1 37.4 36.2 79.2 94.4 80.0 88.9 73.8 140.0 83.4 68.2 97.5 92.0 64.4 58.8 89.0 81.5 98.8 40.0 48.6 119.4 31.0 81.4 51.9 115.4 88.8 31.9 67.2 105.2 96.9 54.6 71.1 36.5 57.5 53.0 166.9 46.7 71.4 57.0 73.9 80.8 99.1 52.5 37.7 72.7 138.6 89.7 60.3 39.7 29.6 166.3 107.6 64.9 23.6 89.0 86.6 89.2 60.4 76.7 86.5 51.2 85.6 46.5 130.8 76.6 82.8 27.5 54.9 29.0 24.4 69.2 23.9 15.5 18.2 23.2 52.7 17.1 19.4 23.2 32.3 26.5 78.2 18.7 23.6 48.3 52.7 55.4 61.4 56.2 57.8 73.1 64.8 69.4 81.3 56.8 60.0 63.1 37.8 60.9 53.9 14.4 50.0 114.3 35.6 47.2 64.9 85.6 57.6 26.5 28.6 34.3 59.5 64.4 125.1 44.9 59.5 174.4 158.5 62.4 66.4 108.8 44.2 57.2 56.8 44.2 38.9 43.1 51.0 29.6 62.2 164.1 58.9 25.4 31.4 20.9 106.3 101.0 41.5 67.6 128.1 111.0 169.5 22.1 14.3 117.9 76.5 26.2 86.2 46.0 49.4 15.1 32.0 81.5 68.4 24.0 35.8 58.6 120.2 193.4 52.1 78.8 13.1 26.1 35.9 92.3 65.9 97.6 140.4 92.9 59.1 51.0 76.1 70.7 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHH1 KIAA1200 ENSG00000054690 "Pleckstrin homology, MyTH4 and FERM domain containing H1" Q9ULM0 14 67533290-67589612 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 158.0" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 10.2;BEWO: 9.7;RT4: 10.2;SK-MEL-30: 12.0;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047707, HPA051964" Uncertain Approved Centrosome NA NA "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "HPA047707: AB_2680126, HPA051964: AB_2681675" "unprognostic (2.47e-2)" "unprognostic (9.57e-2)" "unprognostic (3.94e-2)" "prognostic favorable (8.03e-5)" "unprognostic (4.74e-1)" "unprognostic (9.15e-3)" "unprognostic (8.43e-5)" "unprognostic (1.54e-2)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.85e-1)" "prognostic favorable (4.03e-7)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.26e-4)" 0.9 4.0 20.9 1.3 72.6 0.0 2.5 44.6 51.6 2.9 0.0 6.7 11.7 1.4 8.3 1.2 3.4 2.1 0.7 24.9 31.9 2.1 0.4 0.7 0.1 78.9 59.7 0.2 7.7 9.5 4.3 1.1 71.2 10.3 6.7 7.3 22.8 2.3 0.9 4.3 9.3 0.8 36.8 0.9 6.3 1.8 59.7 1.1 38.9 0.4 0.3 1.4 0.9 158.0 5.3 1.2 2.0 10.2 0.2 0.0 9.7 0.0 0.0 0.1 0.1 3.2 1.6 0.0 1.6 0.0 0.9 2.3 3.6 0.9 0.1 0.3 3.5 0.0 1.8 2.1 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 1.3 4.0 0.0 0.0 7.6 0.0 0.2 3.0 6.0 0.6 0.1 0.3 1.5 1.1 10.2 2.7 2.5 0.9 1.9 12.0 4.7 9.7 2.1 0.0 0.8 3.6 1.0 0.6 0.0 0.0 0.0 0.5 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 72.6 44.6 51.6 24.9 31.9 78.9 59.7 71.2 36.8 59.7 158.0 0.1 3.2 6.4 19.9 0.7 0.1 0.7 3.1 1.2 16.7 5.8 6.0 3.6 2.8 3.4 9.2 39.6 3.0 1.4 21.2 3.9 2.2 0.6 19.1 2.0 0.7 7.3 0.0 13.4 4.0 0.3 0.6 29.0 18.0 0.0 67.7 0.0 0.2 0.8 3.3 21.9 16.9 0.0 0.6 0.3 0.7 0.3 1.5 3.6 12.2 0.0 4.6 0.0 34.2 607.7 2.9 7.7 0.4 0.0 4.1 12.8 1.7 3.9 36.6 0.0 1.5 1.0 0.7 1.6 2.3 2.3 10.7 0.3 2.0 16.4 1.2 PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.6;Pancreatic endocrine cells: 38.5;Prostatic glandular cells: 37.9;Squamous epithelial cells: 19.2;Urothelial cells: 52.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 15.1;HaCaT: 26.0;SK-BR-3: 16.6" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" 0.4 1.6 0.0 0.7 0.1 0.4 1.7 0.0 0.1 11.5 0.0 0.6 0.9 0.4 0.3 54.9 0.9 0.7 0.2 0.0 0.0 2.1 0.9 1.1 0.3 0.0 0.0 0.1 1.1 0.5 0.3 0.4 0.0 3.6 0.1 0.0 10.2 1.2 2.1 46.0 0.8 0.1 0.0 1.2 2.0 0.4 0.1 0.1 0.7 0.0 1.6 7.5 24.2 0.0 15.1 1.4 0.0 1.0 0.1 0.7 2.5 6.8 1.7 4.1 1.1 2.0 11.3 0.0 3.2 3.0 5.7 26.0 0.2 4.5 0.7 5.0 1.0 0.0 5.6 3.3 0.6 0.3 0.2 0.2 3.8 2.9 1.6 3.7 0.5 0.0 0.3 4.0 0.2 8.3 0.0 0.3 0.5 2.4 11.0 0.1 0.0 5.6 4.3 4.2 0.1 0.1 7.5 16.6 1.0 0.4 3.2 0.0 3.2 5.3 2.3 0.5 4.6 3.2 0.1 0.1 6.8 2.5 3.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 1.1 0.0 1.9 4.6 29.6 5.0 1.8 0.5 3.8 1.8 0.9 0.0 6.4 0.0 0.0 7.1 1.0 1.9 0.0 13.8 0.0 3.0 1.1 0.7 0.0 0.0 0.0 14.0 2.0 0.9 3.1 8.2 0.0 0.0 0.7 0.3 1.1 3.3 0.0 0.0 8.2 0.3 1.4 0.0 0.0 0.9 1.8 0.0 1.9 0.2 0.0 0.0 0.0 38.5 3.3 0.0 2.5 37.9 0.0 0.1 5.2 0.2 0.0 0.2 1.0 0.0 0.7 19.2 17.3 9.9 2.8 0.0 0.1 52.9 PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 202.3" "Cell type enhanced" "Detected in many" "Early spermatids: 245.9;Langerhans cells: 159.2;Late spermatids: 390.5;Macrophages: 147.9;monocytes: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA061018: AB_2684416" "unprognostic (1.41e-2)" "unprognostic (7.04e-3)" "unprognostic (2.01e-2)" "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-2)" "unprognostic (8.33e-2)" "unprognostic (3.84e-2)" "unprognostic (3.18e-2)" "unprognostic (8.71e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.47e-11)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (6.52e-2)" 27.7 43.2 49.9 53.9 50.1 17.9 22.6 52.8 61.6 32.3 45.5 202.3 17.8 50.7 5.2 17.5 43.5 20.6 59.3 49.5 47.9 15.9 8.7 34.9 49.5 49.8 48.1 28.1 5.1 4.1 14.9 15.1 48.0 45.5 11.5 4.2 11.0 16.2 39.6 11.2 58.4 40.4 48.9 59.9 55.8 83.2 48.0 33.9 13.0 15.2 26.0 97.5 23.6 48.9 14.3 3.4 46.3 36.0 14.4 12.7 3.8 24.8 32.9 31.8 28.1 1.0 0.4 0.4 4.7 28.5 23.9 1.2 23.3 1.1 10.3 86.7 12.1 2.8 1.9 8.9 27.1 20.0 77.7 18.5 1.0 39.8 6.2 30.6 30.6 38.5 5.4 35.9 43.9 6.7 76.0 40.0 43.7 0.0 6.4 68.1 25.2 16.2 5.6 4.1 28.8 46.9 2.0 0.2 18.7 22.1 2.4 19.4 43.4 20.8 24.1 21.9 30.1 14.0 0.4 9.2 83.4 0.2 8.2 2.6 25.9 0.5 5.6 24.8 6.0 20.0 8.2 5.9 20.1 17.2 5.6 4.7 30.9 4.1 23.4 27.3 6.7 9.2 49.9 50.1 52.8 61.6 49.5 47.9 49.8 48.1 48.0 48.9 48.0 48.9 23.5 35.3 8.9 32.3 65.1 21.5 92.7 2.9 4.6 7.9 11.8 17.9 36.4 2.8 2.9 0.0 0.0 1.7 97.5 0.5 1.9 8.8 245.9 17.9 50.2 58.9 17.8 4.2 13.5 7.8 3.3 29.4 4.6 22.0 5.7 24.5 42.5 1.8 107.1 8.4 24.3 0.9 10.2 85.5 159.2 390.5 17.4 147.9 24.9 21.5 151.1 34.0 23.7 9.0 1.6 10.7 0.0 24.5 23.7 50.1 0.2 0.5 1.3 6.2 72.3 7.5 105.0 122.5 17.5 2.9 14.2 1.5 45.6 8.6 0.4 23.0 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 1563.4;skeletal muscle: 507.3" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 2452.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005597, HPA026900" Enhanced NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.59e-4)" 40.1 12.3 1.5 12.3 3.0 0.6 15.9 2.9 4.0 31.7 2.0 148.7 13.6 121.7 21.8 43.9 81.9 92.2 1563.4 1.6 1.6 15.0 1.2 15.4 2.7 1.8 2.0 20.4 3.2 1.3 1.5 0.3 1.8 35.1 24.4 0.2 5.3 37.0 507.3 8.3 41.6 128.4 1.5 3.0 34.1 4.3 2.2 1.0 12.7 230.2 0.9 44.1 22.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 3.0 2.9 4.0 1.6 1.6 1.8 2.0 1.8 1.5 2.2 2.0 4.5 0.0 0.0 0.3 0.2 4.2 0.2 0.0 1.2 1.8 0.4 0.6 2452.8 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 108.2 0.2 0.7 21.4 0.0 0.0 1.0 0.0 0.0 49.1 0.5 0.1 0.0 0.1 0.7 0.1 0.1 0.0 0.9 0.0 0.0 0.0 4.7 25.0 0.9 0.4 3.6 1.0 0.0 0.0 0.0 2.0 1.1 0.1 0.0 11.7 0.0 0.7 0.0 0.0 0.0 0.3 276.1 16.7 248.0 9.2 0.8 0.3 1.6 0.0 0.8 0.0 0.0 0.4 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 264.5;Prostatic glandular cells: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.2;memory B-cell: 211.8;naive B-cell: 305.9" "Group enriched" "Detected in all" 7 "B-cells: 305.9;granulocytes: 80.2" "Cell line enhanced" "Detected in all" "RPMI-8226: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 12.6 18.6 12.5 21.5 13.0 16.6 24.4 15.8 16.1 29.4 36.5 30.2 41.6 16.1 81.7 13.9 28.3 27.9 8.6 12.6 14.4 27.6 33.0 16.0 28.1 12.7 13.5 18.6 114.5 13.7 52.4 14.0 12.4 74.5 35.5 8.5 85.7 30.5 4.8 10.7 40.3 11.4 11.5 28.0 46.1 7.8 13.5 10.2 29.2 3.0 32.3 21.2 14.1 13.0 15.1 29.7 17.4 35.7 33.2 32.1 23.9 42.1 52.7 21.0 27.3 13.8 22.7 1.0 35.1 43.8 30.5 16.5 14.5 30.9 18.2 9.6 9.3 26.6 13.1 40.5 56.3 7.8 30.8 25.3 31.5 29.4 38.3 37.2 34.7 34.9 1.3 67.2 25.9 31.2 17.7 13.0 26.5 61.2 10.0 19.1 12.8 140.0 53.3 19.4 13.6 20.8 17.3 26.5 25.4 15.4 56.9 15.0 21.2 14.8 13.1 25.2 11.3 41.5 29.4 4.5 41.0 20.5 26.1 80.2 12.9 23.4 13.4 13.7 23.0 211.8 17.8 17.7 12.2 305.9 8.8 8.5 8.0 22.4 19.7 26.0 18.0 17.0 12.5 13.0 15.8 16.1 12.6 14.4 12.7 13.5 12.4 11.5 13.5 13.0 22.2 9.6 46.2 0.0 110.8 0.0 81.8 0.0 25.6 5.9 49.4 42.3 0.0 32.9 21.7 75.4 16.7 45.1 14.8 12.4 43.0 68.0 30.6 70.3 27.3 27.9 44.9 9.9 0.0 89.9 43.5 41.5 50.4 54.8 31.5 38.1 17.5 23.4 36.5 62.2 0.0 62.6 0.0 10.1 0.0 8.9 17.7 23.0 0.0 0.0 12.0 37.4 18.6 0.0 0.0 57.2 31.1 9.4 264.5 146.3 74.3 24.9 55.4 3.6 13.1 22.8 18.9 31.4 12.3 20.8 0.0 88.1 25.2 18.5 44.1 59.1 PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.2;Late spermatids: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "HDLM-2: 99.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA018096: AB_1855609" "unprognostic (2.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.03e-1)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (4.38e-2)" "unprognostic (6.95e-3)" "unprognostic (1.33e-1)" "unprognostic (5.26e-2)" "unprognostic (9.06e-2)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.99e-4)" "unprognostic (2.56e-1)" "unprognostic (2.28e-2)" "unprognostic (2.87e-2)" "unprognostic (5.88e-2)" 3.6 6.6 3.8 6.2 4.0 1.5 7.3 7.0 5.0 5.0 8.7 9.3 10.5 4.0 12.7 7.4 3.3 4.6 2.8 4.3 3.3 5.4 18.9 3.4 8.2 3.4 3.6 4.0 17.2 7.7 4.7 7.1 3.6 16.4 9.9 5.1 7.7 4.8 1.9 8.2 11.4 3.4 3.3 6.0 11.3 5.9 3.3 6.1 7.1 1.5 8.4 5.2 5.1 3.5 8.2 8.3 8.8 10.9 6.9 7.7 8.8 5.5 7.1 4.4 5.0 2.2 5.3 7.9 2.2 5.5 10.9 10.0 6.2 7.8 4.6 99.2 5.9 15.7 8.7 11.3 6.3 5.7 11.4 8.5 6.2 3.4 7.5 5.8 6.6 8.8 2.7 8.1 5.6 8.8 5.4 15.0 8.1 8.2 2.9 5.3 0.0 6.1 7.6 9.3 22.0 11.1 6.5 5.8 3.5 10.8 8.2 12.7 7.8 3.9 3.3 5.3 3.6 1.7 6.4 2.0 6.1 4.1 3.7 6.8 4.1 3.5 3.1 3.7 3.6 2.6 5.6 4.8 4.2 3.3 9.6 6.9 1.8 4.2 4.4 3.2 8.6 4.1 3.8 4.0 7.0 5.0 4.3 3.3 3.4 3.6 3.6 3.3 3.3 3.5 2.8 6.4 2.7 0.0 2.6 0.0 2.5 0.0 2.8 7.5 4.2 2.7 0.0 5.7 1.3 1.8 2.1 18.6 2.9 9.7 1.9 11.0 82.2 2.1 3.4 3.0 10.9 2.1 0.0 13.9 2.9 2.3 7.1 5.3 0.0 4.1 4.2 15.3 6.5 3.3 0.0 7.3 0.0 4.7 0.0 46.3 2.8 1.7 0.0 0.0 3.0 4.6 3.1 0.0 0.0 10.8 6.5 4.9 1.5 7.5 13.4 2.8 0.0 4.9 0.0 1.7 1.8 0.5 1.1 4.6 0.0 10.4 3.4 3.5 5.1 3.1 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 40.9;Excitatory neurons: 29.0;Extravillous trophoblasts: 63.9;Granulosa cells: 46.9;Syncytiotrophoblasts: 49.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AN3-CA: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.2 43.7 1.9 48.8 0.0 0.6 6.5 53.3 1.3 4.8 81.7 3.4 6.5 1.7 14.0 4.1 2.6 6.5 49.8 40.8 1.9 0.2 0.6 0.0 19.6 22.8 0.9 0.3 0.5 1.8 2.0 21.1 17.2 3.8 7.9 0.4 37.6 2.0 1.8 13.4 15.7 15.0 0.2 15.9 8.8 65.1 1.4 0.3 0.3 0.1 27.4 2.2 28.5 0.3 0.1 0.4 33.9 0.0 0.0 3.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.3 0.4 0.3 0.2 0.7 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.7 0.0 0.1 2.7 0.9 0.3 0.4 0.0 0.2 1.2 0.0 0.2 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 48.8 6.5 53.3 49.8 40.8 19.6 22.8 21.1 15.0 65.1 28.5 0.0 0.0 0.0 18.9 0.0 0.6 0.4 40.9 0.0 21.6 0.3 0.9 3.0 0.0 18.0 0.0 22.9 13.5 0.1 1.7 0.0 0.4 0.3 0.3 4.4 0.3 0.0 0.0 29.0 0.4 63.9 0.5 0.0 0.3 0.0 46.9 0.0 0.0 2.4 0.0 24.2 1.1 12.2 0.0 0.0 0.8 0.0 0.3 1.8 1.0 0.0 3.2 0.0 11.1 13.2 2.9 0.1 0.4 0.0 0.3 20.3 0.4 2.6 19.4 0.0 0.0 4.0 0.6 0.9 0.0 0.6 49.5 0.1 0.6 0.4 1.0 PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" 50.9 88.9 127.6 33.3 134.7 35.4 49.7 131.2 168.4 62.8 129.3 74.7 40.6 45.6 77.3 40.5 60.6 41.6 98.4 127.8 137.5 106.5 191.5 55.5 40.9 133.9 130.9 47.1 46.1 93.4 49.5 46.9 134.1 87.4 54.7 26.7 60.6 55.3 85.1 44.9 51.1 36.4 128.7 58.7 81.6 45.6 137.8 45.8 90.0 93.6 37.6 64.2 45.4 134.7 53.2 68.3 49.1 77.0 72.2 60.6 90.0 32.7 70.3 76.1 85.0 112.9 51.2 61.7 63.7 55.0 83.5 53.6 95.4 61.4 52.9 128.0 119.4 90.0 119.5 169.4 78.7 58.9 38.6 83.0 59.8 51.9 15.0 51.0 83.2 48.0 67.8 78.3 68.4 152.2 77.6 139.5 49.0 121.3 69.3 75.1 49.5 51.8 88.3 79.2 47.4 39.9 23.6 156.9 94.6 52.0 52.4 56.4 51.5 31.4 53.7 37.5 45.5 32.4 35.7 69.0 79.9 95.8 38.8 142.4 111.4 151.9 97.7 114.3 94.2 223.1 105.7 117.7 106.4 187.2 116.4 111.2 31.3 136.2 109.4 99.0 150.0 132.2 127.6 134.7 131.2 168.4 127.8 137.5 133.9 130.9 134.1 128.7 137.8 134.7 84.5 70.5 91.2 30.0 58.2 55.2 91.5 179.2 82.6 54.5 130.1 162.4 154.5 128.7 127.8 196.8 6.2 172.9 48.2 292.0 508.7 70.6 13.5 125.9 116.5 66.9 121.3 56.3 44.9 49.8 105.3 88.5 99.9 114.1 57.1 97.0 83.2 250.4 136.7 35.3 47.4 186.3 187.2 85.3 59.6 16.5 103.2 66.2 136.9 20.6 79.6 168.8 51.5 19.6 32.8 37.7 143.6 124.1 74.6 93.4 162.7 326.7 148.5 41.6 92.1 60.0 128.6 42.5 50.6 113.9 62.4 77.3 52.5 97.2 228.1 117.5 PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 84.2;Peritubular cells: 84.7;Spermatocytes: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003817, HPA015007" Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Focal adhesion sites" "HPA003817: AB_1079646, HPA015007: AB_1855502" "unprognostic (2.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (7.49e-5)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.90e-1)" "unprognostic (5.35e-2)" "unprognostic (3.63e-1)" "unprognostic (5.58e-2)" "unprognostic (4.58e-2)" "unprognostic (1.67e-3)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (2.23e-3)" "prognostic unfavorable (4.51e-5)" 35.5 30.2 75.0 20.3 80.5 8.8 20.6 55.5 85.6 37.6 34.7 56.7 13.9 46.3 54.6 23.4 38.1 24.6 23.3 77.3 90.0 27.8 4.9 15.5 16.4 62.1 62.5 53.4 9.2 8.0 53.1 21.4 62.9 48.8 16.5 59.9 10.9 89.3 12.0 9.8 24.9 52.3 66.9 19.2 26.0 71.0 78.4 19.0 18.5 10.4 12.5 41.7 26.6 70.3 48.2 42.8 72.3 54.1 53.1 56.0 29.9 49.8 27.8 44.5 32.5 40.6 29.2 1.1 33.8 60.7 42.4 31.6 56.0 29.4 45.7 45.7 34.7 27.2 35.8 30.7 56.8 15.3 41.6 49.8 35.1 53.4 33.5 87.4 68.1 28.7 23.9 29.3 61.2 117.6 30.5 37.1 21.8 24.6 149.0 47.5 45.0 1.1 58.8 1.5 85.4 65.5 87.5 19.9 40.4 43.6 97.0 25.6 66.5 89.3 71.7 54.9 41.1 25.7 42.9 14.2 88.3 21.4 30.3 2.9 1.8 4.7 8.5 3.5 5.8 2.8 10.9 8.7 3.9 3.1 10.4 10.0 1.6 5.6 5.3 0.6 14.2 7.3 75.0 80.5 55.5 85.6 77.3 90.0 62.1 62.5 62.9 66.9 78.4 70.3 13.1 6.4 3.0 21.9 8.8 3.8 6.8 5.0 6.2 48.6 7.0 7.5 19.9 2.8 4.1 14.7 12.5 7.5 10.4 6.7 15.6 10.1 84.2 32.2 30.6 13.5 18.7 3.0 31.4 6.7 11.3 20.5 14.3 10.2 16.5 16.6 20.0 1.6 15.6 58.9 28.9 5.4 14.2 6.8 25.9 57.6 32.6 18.8 19.6 12.2 14.1 65.2 10.3 17.1 21.7 30.2 1.4 84.7 10.9 7.4 1.6 26.6 23.1 49.1 72.3 31.2 44.1 87.2 44.4 4.7 3.8 6.0 20.0 43.8 2.5 3.7 PNMA3 "MA3, MA5, MGC132756, MGC132758" ENSG00000183837 "PNMA family member 3" Q9UL41 X 153056409-153060467 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 37.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 42.1;Inhibitory neurons: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.2;SCLC-21H: 1.0" "Low region specificity" "Detected in all" HPA047920 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047920: AB_2680210" "unprognostic (1.66e-2)" "unprognostic (8.97e-3)" "unprognostic (8.70e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (9.43e-2)" "unprognostic (3.10e-3)" "unprognostic (1.16e-1)" "unprognostic (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (6.20e-2)" "unprognostic (7.62e-4)" "unprognostic (1.93e-1)" "unprognostic (5.92e-3)" "unprognostic (2.93e-3)" "unprognostic (7.25e-2)" "unprognostic (7.84e-2)" "unprognostic (2.07e-2)" 0.2 1.3 4.3 0.8 5.2 0.3 0.2 1.5 9.4 0.3 0.3 0.4 0.2 0.3 37.3 0.3 1.6 0.2 1.4 5.0 5.4 1.4 0.4 0.4 1.5 5.5 3.6 0.5 0.3 0.6 9.3 0.1 5.4 0.5 0.1 2.1 0.3 0.4 0.1 0.4 2.2 0.1 2.0 2.5 0.4 8.9 5.9 0.5 1.2 0.2 1.3 0.2 0.3 5.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 1.5 9.4 5.0 5.4 5.5 3.6 5.4 2.0 5.9 5.5 0.1 0.0 0.0 9.4 0.3 0.3 0.0 0.0 0.0 7.5 0.2 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.0 0.0 42.1 0.0 0.0 0.2 0.0 0.0 0.0 3.5 0.4 0.0 0.1 6.7 38.6 0.0 0.0 0.9 0.3 1.4 1.2 0.4 0.0 3.7 0.1 3.4 1.0 9.5 2.7 0.0 0.0 0.4 0.2 0.2 0.0 3.8 0.0 2.9 0.0 0.0 0.3 0.1 2.1 0.0 0.0 0.0 1.0 0.7 0.0 0.1 PNPLA7 "C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2" ENSG00000130653 "Patatin like phospholipase domain containing 7" Q6ZV29 9 137459952-137550402 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 23.6;Inhibitory neurons: 21.5;Oligodendrocytes: 21.0" "Cancer enhanced" "Detected in many" "prostate cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.0;T-reg: 1.2" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 1.2" "Cell line enriched" "Detected in some" 22 "HMC-1: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009130 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "Centriolar satellite" "HPA009130: AB_2268411" "unprognostic (1.49e-1)" "unprognostic (1.40e-2)" "unprognostic (3.61e-3)" "unprognostic (2.38e-2)" "unprognostic (3.68e-2)" "unprognostic (6.69e-3)" "unprognostic (2.72e-3)" "unprognostic (5.14e-4)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "prognostic favorable (2.24e-5)" "unprognostic (1.09e-1)" "unprognostic (2.23e-3)" "unprognostic (2.42e-1)" "unprognostic (6.80e-2)" "unprognostic (8.81e-2)" "unprognostic (3.45e-3)" 9.6 7.0 5.2 2.2 5.3 2.1 11.3 1.9 8.6 17.6 1.2 10.8 2.2 12.3 1.0 2.7 13.0 3.7 6.9 6.6 2.6 6.3 14.0 4.7 4.4 4.6 2.6 21.5 17.9 2.0 8.9 0.6 3.6 22.5 1.4 1.3 15.9 2.7 17.3 14.3 8.4 1.6 2.2 7.0 16.3 2.6 4.2 1.4 17.3 3.4 1.4 10.5 7.6 5.9 0.1 1.0 0.2 0.3 0.8 0.5 0.4 0.8 0.8 0.2 0.2 0.1 0.5 0.6 0.8 0.4 0.4 0.3 0.1 0.0 0.0 1.6 0.9 0.8 1.0 0.3 0.5 0.4 83.7 1.2 0.1 0.3 0.0 1.4 0.1 0.1 0.1 2.3 0.1 1.6 0.2 1.6 0.0 1.2 0.9 2.0 1.3 2.8 0.1 0.3 1.6 0.4 0.1 0.6 0.3 0.2 3.7 1.2 0.6 0.0 0.1 0.4 0.1 0.8 0.2 0.2 1.2 0.8 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.2 1.0 0.3 0.2 0.0 0.0 0.0 0.1 1.2 0.2 5.2 5.3 1.9 8.6 6.6 2.6 4.6 2.6 3.6 2.2 4.2 5.9 3.0 9.6 5.9 56.2 4.8 1.5 1.1 0.9 2.2 2.5 6.5 8.3 3.9 4.3 2.6 1.8 6.2 0.2 2.1 6.6 0.0 0.7 0.5 1.7 4.8 1.2 17.3 0.8 23.6 0.0 0.3 3.6 12.2 3.8 7.0 1.2 2.5 10.2 2.6 5.0 21.5 9.2 0.0 4.5 1.0 0.6 4.4 1.2 0.0 9.4 1.3 2.5 1.0 11.6 21.0 0.6 7.1 1.9 1.6 2.5 3.8 1.0 1.6 9.6 0.0 2.3 2.1 3.1 4.0 0.9 3.3 0.0 2.3 0.6 2.0 0.7 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 PODXL2 "endoglycan, PODLX2" ENSG00000114631 "Podocalyxin like 2" Q9NZ53 3 127629185-127672802 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.6;pituitary gland: 59.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 96.3;Early spermatids: 73.5;Horizontal cells: 82.4;Late spermatids: 153.1;Spermatogonia: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPMI-8226: 118.1;SCLC-21H: 167.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024934, HPA042265" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "CAB024934: , HPA042265: AB_2677920" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (7.02e-2)" "unprognostic (1.07e-2)" "unprognostic (9.74e-2)" "unprognostic (1.79e-2)" "unprognostic (8.97e-3)" "unprognostic (1.81e-1)" "unprognostic (3.89e-1)" "unprognostic (2.67e-1)" "unprognostic (4.05e-3)" "unprognostic (3.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.67e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-3)" 3.8 17.3 45.0 2.7 39.9 1.8 8.8 34.1 50.9 2.9 1.9 9.4 7.2 4.4 2.3 4.2 4.3 4.5 4.1 42.3 65.6 7.2 1.6 2.0 2.2 49.2 50.9 11.2 13.5 5.3 59.0 1.0 54.6 13.1 8.2 21.6 24.9 2.0 3.2 7.6 6.7 1.8 32.9 2.0 14.1 30.8 53.6 1.9 5.5 1.8 2.7 3.1 2.8 40.5 0.3 13.8 37.5 89.2 0.0 0.0 55.2 4.3 0.2 7.9 1.6 28.7 1.5 34.0 33.3 0.6 12.1 0.2 30.9 0.0 0.7 0.2 63.3 0.7 30.9 29.3 1.2 78.1 75.7 1.5 6.6 0.2 0.0 20.9 2.2 0.2 45.6 0.2 2.9 17.6 0.3 0.3 56.2 7.9 66.6 0.2 1.0 118.1 10.9 3.9 167.0 94.0 40.9 86.3 77.2 3.7 22.0 39.2 0.4 0.2 17.2 1.5 27.3 0.2 0.0 26.9 0.9 50.1 25.1 0.0 0.0 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.6 0.5 0.1 45.0 39.9 34.1 50.9 42.3 65.6 49.2 50.9 54.6 32.9 53.6 40.5 1.6 0.0 1.1 10.4 3.4 5.5 3.7 1.3 9.1 96.3 17.5 18.4 0.5 4.3 1.7 9.2 31.3 2.2 4.4 14.3 1.9 6.8 73.5 8.7 2.5 2.2 63.5 5.5 21.3 20.1 5.9 8.2 25.0 12.3 1.3 9.5 0.7 0.7 1.3 82.4 57.7 23.2 4.1 1.3 2.8 153.1 8.7 1.6 21.4 5.6 8.1 19.0 6.2 29.1 12.5 12.9 16.7 5.7 10.4 9.9 10.8 2.9 1.7 49.9 6.6 3.8 9.8 20.4 80.4 10.0 5.5 1.5 3.3 7.5 21.8 3.1 POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102798976 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Extravillous trophoblasts: 23.3;Fibroblasts: 3.8;Hofbauer cells: 3.3;Syncytiotrophoblasts: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.9" "Group enriched" "Detected in many" 5 "NK-cells: 3.9;T-cells: 2.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 44000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" 4.6 2.3 1.5 3.1 2.2 1.6 3.3 2.2 2.4 5.6 1.6 3.5 1.3 11.1 4.3 2.6 4.3 8.1 4.8 1.5 1.5 4.6 7.7 3.4 2.4 1.8 1.7 6.5 1.6 2.8 2.1 12.2 1.9 2.7 2.7 3.4 1.8 4.2 0.8 2.3 2.1 12.5 1.7 3.6 2.4 1.5 1.9 1.9 2.9 2.5 1.9 6.0 3.2 2.7 8.1 6.0 36.8 35.5 37.0 28.5 9.0 21.4 16.4 19.5 33.5 17.1 11.5 0.0 16.7 17.6 10.0 13.3 26.6 10.9 19.5 3.4 22.1 9.8 16.3 18.8 32.1 25.4 34.5 27.0 12.3 14.8 14.2 29.1 43.0 12.3 16.3 0.0 10.5 9.0 11.4 20.8 23.5 11.5 17.9 0.0 26.3 9.5 53.7 0.7 5.5 33.7 21.0 5.6 12.3 30.5 16.1 10.9 13.3 12.8 9.3 14.7 21.6 7.4 14.4 0.0 25.2 0.0 22.6 0.0 0.0 0.0 1.4 0.0 2.4 0.2 0.7 1.1 0.6 0.0 0.2 0.7 0.0 3.9 0.0 0.0 0.9 0.2 1.5 2.2 2.2 2.4 1.5 1.5 1.8 1.7 1.9 1.7 1.9 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 23.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;testis: 2.6" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Excitatory neurons: 77.7;Inhibitory neurons: 42.7;Oligodendrocyte precursor cells: 22.1;Oligodendrocytes: 26.8;Spermatocytes: 23.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035939, HPA035940" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035939: AB_2674875, HPA035940: AB_2674876" "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 2.4 0.6 0.3 0.0 0.4 0.0 1.0 0.2 0.5 0.3 0.0 0.3 0.1 0.3 0.7 0.1 0.4 0.3 0.3 0.3 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.2 0.4 0.1 0.4 0.1 0.0 0.6 0.0 0.2 0.5 0.2 0.4 0.3 0.3 0.1 0.0 0.3 0.3 2.6 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.4 0.0 0.6 0.0 0.3 1.7 0.5 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.2 0.7 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 32.3 1.0 0.9 1.0 0.6 0.6 4.2 3.0 1.5 3.6 1.5 1.7 0.0 0.0 0.2 0.6 0.2 3.9 0.4 8.3 4.2 2.0 1.9 4.8 0.8 77.7 1.0 0.3 2.0 1.5 2.1 0.0 5.5 3.3 1.1 0.7 3.3 42.7 0.0 2.0 1.3 1.0 14.1 4.4 1.3 0.0 15.0 0.7 2.5 1.0 22.1 26.8 0.5 1.1 3.8 1.5 1.0 0.3 0.8 1.9 3.8 0.0 2.9 1.1 23.4 10.4 0.5 1.6 0.0 1.8 4.1 0.3 1.3 POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 405.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 272.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024255 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" 3.6 2.1 0.6 3.8 0.5 0.3 3.3 0.8 0.9 7.9 1.3 95.3 2.8 12.5 2.6 2.0 9.6 10.9 405.4 0.5 0.5 2.4 1.0 2.5 6.7 0.6 0.6 2.0 1.3 8.4 1.3 1.4 0.6 16.3 6.2 0.9 3.3 49.2 77.7 2.8 12.2 24.0 0.5 2.8 10.7 1.0 0.6 1.5 2.4 96.9 2.5 35.3 6.0 0.5 0.1 0.2 0.5 0.0 0.2 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 24.8 0.0 0.0 0.6 2.5 0.0 0.3 0.0 0.2 0.1 0.2 0.1 1.0 0.0 0.2 0.2 0.3 0.5 0.5 0.0 0.7 0.3 0.0 0.4 0.1 0.5 0.4 0.0 0.4 0.8 0.2 0.0 0.2 1.3 0.2 0.7 0.1 0.6 0.5 0.8 0.9 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 4.7 0.0 0.5 1.0 0.6 0.4 0.3 0.5 0.0 3.1 0.9 3.0 272.7 0.0 0.9 0.0 0.0 0.5 2.3 0.4 0.0 0.5 0.3 0.6 0.5 6.4 3.0 0.0 0.8 0.2 0.1 8.0 0.5 0.3 1.3 1.6 1.4 0.2 1.6 1.7 1.2 0.8 0.0 1.0 2.3 0.8 1.2 1.6 0.0 2.8 1.8 1.2 0.0 1.0 1.9 0.5 0.2 1.9 0.0 0.8 0.7 0.3 1.9 2.4 59.2 5.9 11.1 1.0 0.3 0.1 0.6 1.2 1.6 0.6 0.3 0.2 POPDC3 "bA355M14.1, MGC22671, POP3" ENSG00000132429 "Popeye domain containing 3" Q9HBV1 6 105157900-105180014 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;skeletal muscle: 96.3;tongue: 29.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 42.8;Early spermatids: 88.0;Excitatory neurons: 16.6;Late spermatids: 18.2;Oligodendrocytes: 15.0;Skeletal myocytes: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 25.9;RH-30: 15.8;SH-SY5Y: 15.4;U-87 MG: 14.2;WM-115: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012514 Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA012514: " "unprognostic (2.17e-1)" "unprognostic (2.15e-2)" "unprognostic (3.65e-1)" "unprognostic (1.14e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.79e-4)" "unprognostic (2.81e-1)" "unprognostic (1.69e-1)" "unprognostic (5.12e-3)" "unprognostic (2.37e-1)" "unprognostic (2.83e-9)" "unprognostic (6.25e-2)" "unprognostic (1.24e-1)" "unprognostic (3.75e-3)" "unprognostic (1.33e-2)" 0.5 0.3 5.1 0.3 6.8 0.0 0.2 5.8 10.0 0.5 4.8 2.5 0.1 0.9 1.5 1.8 0.4 0.7 23.0 6.2 6.2 0.2 0.0 0.1 0.1 6.3 6.4 0.2 0.1 0.1 4.4 0.7 6.2 0.8 0.0 0.5 1.3 0.3 96.3 0.2 0.5 0.0 6.3 0.0 3.2 3.9 6.0 0.0 0.2 29.6 0.0 1.3 0.4 9.7 1.3 1.6 0.5 0.2 2.7 6.8 0.6 2.9 2.5 4.5 5.2 0.0 1.6 0.1 1.1 5.5 25.9 0.0 1.7 1.5 3.6 0.0 4.1 0.0 1.1 0.0 0.1 0.0 0.0 2.3 0.3 7.5 1.0 1.4 0.3 0.1 3.4 7.0 12.8 0.0 0.0 1.5 3.0 0.0 6.3 0.5 15.8 0.0 0.0 0.0 7.5 15.4 0.0 0.1 11.5 1.4 0.0 6.2 6.5 3.4 0.0 2.1 10.7 0.0 0.0 0.0 14.2 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.8 5.8 10.0 6.2 6.2 6.3 6.4 6.2 6.3 6.0 9.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 42.8 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 88.0 1.5 1.0 0.4 0.0 0.0 16.6 0.0 1.2 2.0 0.0 5.6 0.0 0.1 0.0 0.0 0.3 0.0 4.9 0.0 2.0 0.0 0.0 18.2 0.6 0.7 0.0 2.8 2.0 0.0 0.0 0.5 15.0 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 32.0 3.5 2.9 5.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 POTEG "A26C2, CT104.4, POTE-14, POTE14, POTE14alpha" ENSG00000187537 "POTE ankyrin domain family member G" Q6S5H5 14 19402486-19434341 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "prostate: 1.1" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.1" "Cancer enhanced" "Detected in single" "prostate cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.01e-1)" "unprognostic (1.51e-1)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (2.69e-2)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (2.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 7.6 15.0 4.7 11.1 3.5 2.9 4.1 4.5 10.6 2.7 3.1 5.0 7.6 3.7 11.3 2.9 7.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 POTEH "A26C3, ACTBL1, CT104.7, POTE22" ENSG00000198062 "POTE ankyrin domain family member H" Q6S545 22 15690026-15721631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "prostate: 2.1;testis: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Testis - DNA repair" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.66e-2)" "unprognostic (1.02e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POTEI POTE2beta ENSG00000196834 "POTE ankyrin domain family member I" P0CG38 2 130459455-130509707 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.2;prostate: 2.5;testis: 3.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.3;Breast myoepithelial cells: 1.5;Cardiomyocytes: 1.9;Prostatic glandular cells: 1.9;Spermatocytes: 5.8;Spermatogonia: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;BEWO: 1.4;K-562: 2.0;MCF7: 1.2;RPMI-8226: 1.2;U-2 OS: 3.7;U-266/70: 1.2" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (2.52e-3)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "unprognostic (1.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (8.59e-2)" "unprognostic (2.67e-1)" "unprognostic (2.22e-3)" "unprognostic (5.52e-2)" "unprognostic (1.47e-1)" "unprognostic (3.38e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.0 0.0 0.0 0.0 0.0 1.7 0.8 0.0 0.1 0.0 0.1 0.1 0.6 2.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.2 3.3 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 1.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.3 0.5 0.0 0.0 0.0 3.7 0.1 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.1 0.2 1.0 1.7 0.8 0.6 3.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.3 1.5 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.9 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.1 0.7 0.0 0.0 0.0 0.2 5.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 POTEM "ACT, P704P, POTE14beta" ENSG00000222036 "POTE ankyrin domain family member M" A6NI47 14 18967434-19003752 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "prostate: 18.7" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;K-562: 4.2;U-2 OS: 7.4" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "unprognostic (6.16e-2)" 0.1 0.2 0.7 0.2 0.3 0.2 0.3 0.4 0.8 0.2 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.3 0.5 0.1 0.0 0.2 0.2 0.4 0.1 0.3 0.2 0.1 0.0 0.4 0.4 18.7 0.1 1.1 0.3 0.1 0.2 0.5 0.1 0.1 0.0 0.3 0.2 4.1 0.3 0.1 0.6 0.1 0.1 0.1 0.0 0.9 0.7 0.7 0.3 0.6 0.1 0.1 3.2 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.4 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.2 0.3 1.0 1.0 0.0 0.3 0.8 0.1 0.2 0.4 0.0 0.2 0.1 0.1 4.2 1.8 0.2 0.7 0.4 0.3 0.8 0.0 0.5 0.3 0.3 0.8 0.2 0.2 0.2 1.1 0.3 1.7 0.1 0.9 2.1 0.2 0.5 0.3 7.4 0.4 0.3 0.8 1.5 0.1 0.2 0.3 0.4 0.7 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.7 0.3 0.4 0.8 0.3 0.5 0.4 0.1 0.4 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PPFIA3 "KIAA0654, LPNA3, MGC126567, MGC126569" ENSG00000177380 "PTPRF interacting protein alpha 3" O75145 19 49119544-49151026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;pituitary gland: 45.0;skin 1: 42.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 40.8;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 23.1;PC-3: 36.1;SK-BR-3: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043567, HPA050340" Enhanced Uncertain "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli fibrillar center, Vesicles" "HPA043567: AB_2678558, HPA050340: AB_2681096" "prognostic unfavorable (3.09e-4)" "unprognostic (4.70e-2)" "unprognostic (5.14e-3)" "prognostic favorable (8.65e-4)" "unprognostic (3.46e-1)" "prognostic favorable (6.46e-7)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.27e-1)" "unprognostic (8.36e-2)" "unprognostic (9.41e-3)" "unprognostic (5.21e-3)" "unprognostic (8.52e-2)" "unprognostic (1.00e-2)" "unprognostic (1.22e-2)" "unprognostic (1.52e-1)" "unprognostic (3.92e-2)" "unprognostic (1.32e-1)" 2.0 4.5 16.4 0.8 18.8 0.2 2.7 11.7 28.6 4.6 0.0 6.6 3.0 2.2 0.3 14.1 1.9 0.6 3.1 18.2 11.4 3.1 2.7 2.9 0.8 10.1 8.7 1.3 4.7 2.1 45.0 0.4 9.9 5.6 1.0 3.7 5.3 0.6 1.4 42.3 3.7 0.4 3.5 2.2 2.4 4.2 11.7 2.4 2.8 0.2 1.1 1.4 8.1 16.6 3.3 3.3 3.3 8.0 0.1 0.0 6.0 0.4 0.4 1.5 2.2 2.2 1.3 7.3 4.3 0.4 2.4 1.7 5.0 0.7 0.4 7.9 10.8 4.6 3.5 1.7 0.4 1.9 11.4 0.4 1.8 1.0 0.5 0.7 0.0 12.1 9.0 11.2 0.1 14.2 2.3 3.2 1.4 23.1 36.1 7.6 6.5 3.6 0.5 1.6 7.2 9.5 1.3 29.7 3.3 0.0 16.5 4.4 0.7 1.7 6.1 1.1 0.2 21.0 18.2 5.4 1.7 7.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 18.8 11.7 28.6 18.2 11.4 10.1 8.7 9.9 3.5 11.7 16.6 15.7 0.0 0.6 8.5 0.8 7.1 8.0 3.5 11.4 40.8 10.4 6.1 4.2 8.6 3.0 5.5 14.6 0.5 3.6 19.3 19.6 2.7 1.2 1.3 3.6 15.2 26.5 2.7 19.9 4.4 2.1 3.4 3.6 2.4 0.0 2.7 23.2 8.6 2.5 43.7 21.5 26.3 8.2 2.2 2.4 1.7 5.6 2.7 16.0 2.8 0.0 16.2 0.0 10.6 2.7 1.9 13.7 3.8 1.2 18.2 15.0 4.6 0.9 17.9 0.0 0.6 5.5 2.5 5.9 8.7 11.8 0.5 0.7 13.2 20.4 6.3 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755854-58985179 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 39.2;retina: 22.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.9;Horizontal cells: 77.4;Inhibitory neurons: 288.4;Oligodendrocyte precursor cells: 109.1" "Cancer enhanced" "Detected in some" "glioma: 2.7;prostate cancer: 3.0" "Group enriched" "Detected in many" 4 "cerebral cortex: 31.6;hippocampal formation: 39.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 12.2;HAP1: 19.9;MOLT-4: 9.9;SCLC-21H: 9.1;SH-SY5Y: 18.7;THP-1: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.1 5.5 5.3 0.1 4.8 0.0 0.1 1.0 31.6 0.2 0.0 0.1 0.1 0.3 0.9 0.0 1.5 0.1 1.0 39.2 7.3 0.7 1.0 0.2 0.2 1.9 4.2 0.2 0.6 0.3 1.3 0.0 3.2 1.4 0.0 22.3 0.2 0.0 0.0 0.0 0.2 0.3 0.3 0.2 0.5 6.7 8.0 0.2 0.1 0.1 0.2 0.1 0.1 2.3 0.0 0.1 12.2 0.6 0.0 0.0 0.9 0.0 0.0 0.9 1.4 0.0 0.0 8.0 0.1 0.1 2.7 0.0 19.9 0.0 0.5 0.2 5.9 0.0 0.2 0.0 1.3 0.6 2.6 0.3 1.6 0.1 0.0 0.6 0.0 4.9 2.1 0.0 0.0 3.6 9.9 0.0 3.5 0.0 1.0 0.0 1.5 0.0 0.0 0.0 9.1 18.7 0.3 0.0 1.3 0.1 0.0 8.7 0.0 0.0 2.2 0.0 2.9 0.1 0.1 5.4 0.3 0.0 2.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 4.8 1.0 31.6 39.2 7.3 1.9 4.2 3.2 0.3 8.0 2.3 0.1 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 22.0 0.1 0.4 3.3 0.0 1.8 0.0 31.3 0.0 0.0 0.1 0.0 0.0 30.8 3.9 0.1 0.3 3.0 0.0 220.9 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.4 0.1 77.4 288.4 0.0 0.0 0.3 0.0 17.6 0.0 0.1 0.0 5.6 0.0 4.2 0.0 109.1 38.4 0.0 0.2 0.4 0.0 1.3 0.0 0.1 0.0 13.8 0.0 0.0 0.5 12.1 2.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643994-62935150 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;parathyroid gland: 42.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 123.5;Glandular and luminal cells: 81.6;Inhibitory neurons: 162.1;Microglial cells: 89.9;Oligodendrocytes: 341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 80.6;HMC-1: 62.7;SK-BR-3: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB020694: , HPA044244: AB_2678871, HPA058777: AB_2683816" "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" "unprognostic (9.51e-2)" "unprognostic (8.61e-3)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (5.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" "unprognostic (5.53e-3)" "unprognostic (2.19e-1)" "prognostic favorable (2.72e-5)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" "unprognostic (8.04e-3)" "unprognostic (1.14e-1)" 2.2 1.5 12.0 1.2 12.7 3.1 4.9 30.0 16.0 7.5 5.7 2.4 3.1 6.2 6.7 0.6 6.5 6.7 2.4 13.3 15.7 10.6 3.4 2.7 1.2 11.1 11.3 9.6 3.9 42.4 8.2 6.5 14.9 13.4 3.0 26.7 11.4 6.0 1.1 0.8 1.7 1.5 7.8 0.9 5.7 0.9 16.5 4.3 3.2 1.3 1.7 2.1 0.3 16.2 1.2 12.4 2.2 0.2 0.5 0.0 26.5 2.9 2.9 1.8 0.6 80.6 5.7 0.0 2.7 1.4 1.8 1.6 8.7 0.2 1.1 0.2 4.3 15.2 2.4 18.4 0.1 4.6 62.7 0.1 0.3 0.0 0.7 1.9 0.3 2.7 4.0 0.0 1.3 9.5 1.5 2.2 15.9 4.1 5.9 2.1 5.6 23.0 18.1 28.3 6.9 0.0 5.0 35.6 12.1 8.5 19.6 2.7 0.2 0.5 1.5 0.2 0.9 3.3 21.4 4.1 0.2 0.1 1.2 2.9 0.7 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.1 0.6 0.0 0.0 0.1 12.0 12.7 30.0 16.0 13.3 15.7 11.1 11.3 14.9 7.8 16.5 16.2 4.6 6.4 4.7 25.5 1.0 0.1 0.3 3.0 0.0 9.4 9.5 3.4 2.4 12.8 5.9 16.5 27.1 22.2 0.0 0.7 3.9 4.2 8.5 27.6 25.3 6.5 9.0 3.8 123.5 6.3 2.1 1.3 7.7 81.6 14.5 0.3 9.7 6.1 6.1 11.8 162.1 2.0 6.1 1.6 2.1 10.1 0.9 2.1 3.6 89.9 2.1 6.4 0.0 41.7 341.4 4.5 2.1 1.5 0.5 4.3 0.1 8.5 14.0 10.9 0.0 0.6 1.7 0.0 0.5 0.5 0.1 6.8 1.3 2.8 2.4 0.5 PPP1R12A "M130, MBS, MYPT1" ENSG00000058272 "Protein phosphatase 1 regulatory subunit 12A" O14974 12 79773563-79935460 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 353.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041296, HPA071956" Approved Supported "Actin filaments,Cytosol" NA NA 270000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments, Cytosol" "HPA041296: AB_2677394, HPA071956: AB_2732192" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-1)" "unprognostic (5.60e-3)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (1.61e-1)" "unprognostic (9.69e-3)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-3)" "unprognostic (5.50e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" 31.5 18.6 21.2 32.3 26.6 57.5 21.7 25.3 65.3 34.1 15.0 73.3 22.8 66.2 31.1 71.2 40.9 36.6 28.0 27.7 20.3 18.2 14.2 24.6 31.9 14.3 14.5 27.4 11.0 18.5 11.2 41.6 14.2 67.6 35.4 14.6 19.0 84.8 20.5 17.6 27.6 83.7 14.1 30.8 29.2 23.5 20.7 34.3 24.9 27.2 27.8 64.5 27.7 27.0 42.9 36.5 49.3 28.5 36.8 36.2 45.8 84.0 46.5 53.1 35.2 34.9 20.7 36.9 33.4 113.8 21.4 33.4 38.6 32.9 63.8 51.3 24.3 98.2 40.5 24.1 29.1 64.8 59.5 30.7 24.3 53.6 49.1 60.1 37.2 36.7 41.1 43.0 57.0 27.7 71.4 34.3 39.1 18.8 25.2 57.9 54.4 27.8 31.4 66.6 23.8 17.9 66.3 23.2 28.5 45.1 32.4 30.9 56.8 56.3 29.9 40.1 48.2 28.3 27.8 48.6 19.2 36.3 49.3 155.1 44.4 197.4 62.8 47.5 56.5 56.8 59.7 66.8 41.8 52.8 47.3 61.3 187.2 98.2 70.4 35.3 69.6 46.3 21.2 26.6 25.3 65.3 27.7 20.3 14.3 14.5 14.2 14.1 20.7 27.0 108.4 76.9 65.9 168.5 79.7 84.5 69.0 59.1 57.5 82.2 30.7 69.0 127.4 32.9 61.5 53.3 35.5 66.7 113.4 44.9 15.6 50.9 111.3 47.5 113.6 93.6 44.9 66.3 240.4 40.0 82.0 82.4 42.8 81.2 121.4 66.6 55.0 27.5 78.0 102.6 135.4 37.7 44.7 57.5 100.8 64.2 86.3 92.8 60.5 132.1 112.0 52.2 120.5 353.9 132.9 55.9 42.7 147.4 60.7 52.0 34.3 26.3 41.0 61.4 210.4 74.6 332.7 133.4 89.8 50.9 81.1 83.7 119.7 81.5 41.3 63.6 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PPP1R12C "AAVS1, DKFZP434D0412, LENG3, MBS85, p84, p85" ENSG00000125503 "Protein phosphatase 1 regulatory subunit 12C" Q9BZL4 19 55090914-55117637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 96.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043532 Approved NA NA 29000 "Cluster 24: B-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "HPA043532: AB_10961273" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (8.52e-3)" "unprognostic (7.92e-2)" "unprognostic (3.24e-2)" "unprognostic (2.78e-2)" "unprognostic (3.21e-3)" "unprognostic (5.40e-2)" "unprognostic (2.99e-1)" "unprognostic (1.20e-1)" "prognostic favorable (4.10e-5)" "unprognostic (9.60e-2)" "unprognostic (3.01e-3)" "unprognostic (8.36e-2)" "unprognostic (3.15e-1)" "unprognostic (3.01e-1)" "unprognostic (2.68e-3)" 103.0 67.3 86.5 49.6 80.5 55.8 96.2 71.7 102.8 158.4 91.4 298.6 61.1 200.7 26.0 80.6 143.2 26.2 283.7 86.6 79.2 96.3 85.8 107.0 44.8 93.3 83.0 104.6 86.3 36.5 108.3 36.8 86.5 137.9 19.4 15.4 60.4 57.7 43.4 75.0 135.9 58.4 69.9 138.9 132.2 150.8 87.1 28.9 85.8 22.3 23.1 173.6 101.4 80.6 52.9 66.7 36.2 43.8 39.8 24.1 84.0 58.8 41.9 35.3 38.9 24.1 37.6 77.9 25.0 33.8 36.0 49.7 12.6 23.2 12.0 63.6 120.7 52.0 67.5 40.2 82.0 38.1 90.1 37.8 29.0 35.1 22.4 29.2 39.7 39.8 40.3 87.1 32.6 32.7 45.4 55.3 26.2 34.8 67.6 62.0 29.9 31.4 32.4 89.2 47.0 37.4 42.1 35.7 37.9 17.9 22.9 76.6 82.9 86.0 41.5 43.1 62.3 43.0 37.7 42.8 78.4 77.5 54.2 0.0 1.5 2.6 1.1 1.2 0.8 1.3 1.0 0.9 0.9 2.5 0.8 1.1 1.6 0.6 2.4 1.5 0.7 0.7 86.5 80.5 71.7 102.8 86.6 79.2 93.3 83.0 86.5 69.9 87.1 80.6 28.2 22.4 15.5 19.9 9.6 11.5 5.1 4.6 1.8 31.3 11.4 12.2 50.3 8.6 8.6 11.0 22.9 6.2 20.4 31.9 1.9 8.4 19.4 9.2 25.4 23.2 5.3 6.5 15.1 15.1 10.3 18.6 33.1 15.1 6.3 96.2 23.6 17.4 15.7 37.0 16.7 18.7 8.2 24.4 16.5 9.1 17.1 20.2 17.8 12.2 14.2 19.1 11.3 10.6 16.2 13.3 20.1 25.6 13.0 7.6 17.1 7.9 7.8 21.7 39.5 15.6 45.5 19.7 13.4 8.9 8.2 10.1 13.2 28.5 13.2 8.7 PPP1R14A "CPI-17, PPP1INL" ENSG00000167641 "Protein phosphatase 1 regulatory inhibitor subunit 14A" Q96A00 19 38251237-38256532 "Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 492.0;intestine: 450.3" "Cell type enhanced" "Detected in many" "Adipocytes: 332.5;Granulosa cells: 435.0;Leydig cells: 341.1;Peritubular cells: 656.0;Sertoli cells: 979.5;Smooth muscle cells: 465.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 299.4;naive B-cell: 283.9;plasmacytoid DC: 246.9" "Group enriched" "Detected in many" 24 "B-cells: 299.4;dendritic cells: 246.9" "Group enriched" "Detected in some" 4 "A549: 164.1;EFO-21: 112.2;K-562: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005044, CAB009803, HPA042097, HPA054534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 880000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear bodies" "CAB005044: AB_562091, CAB009803: AB_2168720, HPA042097: AB_2677846, HPA054534: AB_2682518" "unprognostic (5.40e-2)" "unprognostic (4.00e-3)" "unprognostic (4.02e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-1)" "unprognostic (8.92e-3)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.25e-5)" "prognostic unfavorable (7.12e-4)" "unprognostic (4.13e-1)" "unprognostic (5.81e-2)" "unprognostic (2.22e-2)" 134.0 144.2 175.2 22.1 347.5 2.9 111.9 321.5 226.5 149.7 63.2 450.3 18.6 273.5 5.2 47.6 153.7 14.8 94.6 175.2 219.6 53.3 17.9 163.1 2.6 402.3 322.9 125.1 31.1 2.8 12.6 34.1 336.3 142.0 12.6 0.3 19.0 86.1 27.5 28.6 82.1 57.2 222.0 101.2 140.3 77.6 365.3 1.7 25.8 12.3 1.4 301.6 106.1 492.0 0.0 164.1 0.4 0.0 1.0 0.0 6.1 10.8 0.0 0.1 0.0 12.8 0.2 0.0 112.2 1.0 0.0 0.5 13.6 0.2 0.0 1.4 0.0 25.5 0.0 0.0 4.6 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 64.5 0.3 0.0 0.8 0.0 0.3 4.9 0.0 0.0 0.2 2.4 0.4 0.4 0.0 3.5 0.2 0.0 0.0 0.1 9.2 0.0 0.4 0.4 0.0 0.8 0.4 0.0 0.4 0.0 0.5 0.2 0.0 0.1 11.3 0.6 1.2 0.1 0.7 0.2 299.4 0.2 0.4 44.3 283.9 0.6 0.1 1.7 8.7 0.2 246.9 0.2 21.6 175.2 347.5 321.5 226.5 175.2 219.6 402.3 322.9 336.3 222.0 365.3 492.0 332.5 0.0 1.1 1.3 29.9 9.6 3.0 1.2 3.4 0.4 8.8 209.8 19.6 2.8 0.7 0.0 0.0 48.3 48.7 32.7 0.0 0.7 14.1 15.4 239.5 108.5 1.8 34.7 0.5 10.9 7.4 66.8 2.0 10.8 3.8 435.0 224.5 2.3 9.5 0.0 0.6 0.4 0.0 5.6 24.6 42.1 341.1 41.4 8.8 14.0 66.1 0.5 4.1 3.5 155.6 2.2 2.6 656.0 4.8 2.4 3.8 0.3 0.0 1.6 979.5 8.7 465.2 9.9 46.2 0.6 8.0 26.4 3.7 66.0 0.4 1.2 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633071 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 908.0;tongue: 448.5" "Group enriched" "Detected in many" 8 "Astrocytes: 201.8;Cardiomyocytes: 232.0;Hepatocytes: 64.2;Muller glia cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 41.9;HHSteC: 51.7;hTERT-RPE1: 85.4;LHCN-M2: 102.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027041 Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027041: AB_1855649" "unprognostic (2.11e-1)" "unprognostic (1.86e-3)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.15e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.38e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-3)" "unprognostic (5.63e-3)" "unprognostic (1.59e-2)" "unprognostic (5.48e-3)" "unprognostic (8.44e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" 14.1 12.2 39.3 3.4 51.5 0.0 9.9 39.8 44.6 97.1 21.4 16.2 4.0 10.3 12.0 106.8 10.2 14.4 170.5 40.1 42.9 11.6 164.2 12.3 1.4 44.1 55.1 10.2 18.7 4.5 5.7 15.6 43.9 29.1 4.1 83.2 28.4 35.7 908.0 17.0 5.8 15.4 39.6 3.0 17.5 2.5 42.4 0.5 2.7 448.5 6.2 19.8 136.7 38.0 0.0 6.6 1.8 26.8 11.9 5.6 0.0 29.8 23.2 12.0 12.8 0.0 2.2 0.0 1.2 28.0 4.8 1.6 0.7 3.2 22.0 0.0 0.1 0.4 41.9 4.8 51.7 0.0 0.0 19.1 5.2 7.6 0.4 85.4 3.0 0.0 14.4 0.0 102.5 1.0 0.0 0.0 1.7 0.0 0.0 0.0 6.4 0.0 1.1 26.2 0.9 1.8 0.0 0.0 0.0 0.0 0.2 4.5 20.3 5.3 5.2 7.0 4.3 0.2 0.6 0.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 51.5 39.8 44.6 40.1 42.9 44.1 55.1 43.9 39.6 42.4 38.0 2.4 0.0 0.0 201.8 0.4 4.6 9.3 0.8 0.6 9.7 4.8 2.5 232.0 1.5 0.2 3.7 0.0 0.2 0.0 0.3 7.9 3.1 0.1 0.3 0.7 3.5 10.1 0.0 1.7 11.4 0.5 11.9 0.0 0.6 0.0 0.4 2.5 64.2 1.4 18.5 3.0 0.5 2.0 1.6 1.5 0.1 2.8 0.6 12.4 5.6 0.0 133.1 0.0 3.5 0.5 4.0 0.1 7.5 0.0 2.5 0.0 1.8 0.4 12.8 0.0 9.4 18.6 0.7 1.7 5.4 4.0 0.3 0.7 0.1 0.1 0.7 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease variant, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.1" "Cell type enhanced" "Detected in all" "Excitatory neurons: 933.8;Inhibitory neurons: 403.0;Oligodendrocyte precursor cells: 348.3" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 94000 "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 24.7 17.5 48.5 15.7 144.1 17.2 20.5 63.2 125.6 17.0 0.0 19.5 11.6 11.8 13.1 14.4 13.8 13.3 9.2 97.4 25.0 11.2 17.0 19.9 14.7 14.6 11.0 17.9 9.4 8.9 9.0 13.0 15.7 66.0 16.1 27.6 22.2 38.4 51.2 22.9 12.9 15.5 24.7 14.5 22.4 10.6 23.9 12.8 13.2 29.0 18.3 20.7 16.0 54.3 48.3 33.8 9.3 18.0 50.4 37.9 15.8 51.9 47.8 19.8 21.6 18.3 59.0 22.4 20.9 47.6 25.6 23.5 33.3 69.6 34.9 56.0 15.1 35.4 45.8 25.2 36.8 59.0 17.8 39.6 35.6 45.3 51.4 39.1 38.8 14.5 14.4 61.1 33.5 58.0 12.2 44.2 15.4 55.7 20.7 22.1 83.2 26.5 20.0 38.3 71.5 26.2 43.1 35.4 24.6 12.5 32.3 33.4 42.1 48.7 54.8 44.7 34.7 28.5 31.5 40.1 26.6 31.5 13.1 82.5 31.0 73.5 35.7 33.1 41.6 74.1 33.2 34.8 28.2 62.8 15.5 31.0 123.7 65.1 45.1 51.9 25.3 21.1 48.5 144.1 63.2 125.6 97.4 25.0 14.6 11.0 15.7 24.7 23.9 54.3 143.3 76.9 58.6 284.1 96.8 168.8 36.2 29.5 34.7 89.8 93.8 51.8 25.0 38.6 21.9 31.3 39.6 39.6 81.4 60.0 33.2 21.3 3.2 39.3 56.2 100.8 127.4 32.0 933.8 31.6 84.0 75.6 59.1 42.8 35.4 22.1 53.2 39.7 38.3 18.5 403.0 44.2 14.2 61.8 135.3 8.4 65.0 58.2 92.5 281.1 64.3 21.2 56.7 348.3 139.1 53.3 115.4 60.9 63.8 127.6 23.9 51.9 25.3 82.9 13.1 66.9 67.5 12.7 26.5 27.9 172.0 27.5 69.1 76.2 55.9 39.5 PRAC1 "C17orf92, PRAC" ENSG00000159182 "PRAC1 small nuclear protein" Q96KF2 17 48721719-48722518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "intestine: 206.4;prostate: 109.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 326.1;Enteroendocrine cells: 908.1;Intestinal goblet cells: 717.3;Paneth cells: 328.7;Undifferentiated cells: 624.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 291.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 32 "PC-3: 379.0" HPA047871 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA047871: AB_2680195" "unprognostic (7.59e-2)" "unprognostic (2.43e-2)" "unprognostic (2.04e-1)" 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.2 0.3 4.4 0.1 106.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 109.0 206.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 12.4 12.8 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 379.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.1 0.4 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 1.0 0.0 110.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 326.1 0.0 0.0 0.7 0.0 0.0 0.4 908.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 328.7 0.0 0.0 101.9 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.9 0.0 624.3 63.1 PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.7;prostate: 13.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.2;Distal enterocytes: 17.5;Early spermatids: 32.9;Enteroendocrine cells: 31.9;Intestinal goblet cells: 15.5;Late spermatids: 60.5;Prostatic glandular cells: 20.2;Undifferentiated cells: 22.7;Urothelial cells: 30.1" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 49.3;REH: 20.0" "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.3 9.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.4 2.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.5 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 49.3 20.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.2 0.0 2.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 32.9 0.0 0.0 0.1 31.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.3 60.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.4 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 22.7 30.1 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cell line enhanced" "Detected in many" "Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 6.6 2.1 1.6 20.0 1.6 20.3 6.8 5.5 1.8 15.7 3.1 15.2 9.2 17.2 1.3 55.2 5.5 12.7 1.7 1.5 2.8 2.5 4.5 10.1 15.9 3.2 1.8 4.9 1.9 2.5 1.4 5.1 2.7 3.4 17.2 1.3 9.3 2.4 4.3 9.1 12.6 5.5 2.4 13.6 15.2 1.2 2.9 4.2 9.0 2.2 27.8 19.6 20.2 3.4 1.4 0.5 1.1 0.0 1.6 2.1 0.2 7.2 23.3 2.3 3.7 1.4 9.2 2.0 0.4 13.8 0.3 0.5 0.0 3.6 2.5 21.7 0.1 0.4 4.9 0.0 3.6 0.8 1.6 2.3 11.6 3.3 9.7 0.7 2.9 1.0 1.4 212.1 0.4 0.0 0.1 0.5 0.8 1.4 0.0 0.5 0.0 42.4 2.1 0.3 0.0 0.3 1.0 0.9 0.0 1.6 1.0 2.4 1.5 3.1 1.8 2.1 7.2 81.5 57.0 4.9 5.1 1.3 2.1 2.4 0.8 11.1 22.1 1.2 34.0 2.5 20.5 20.2 0.5 1.0 1.8 11.3 12.5 4.7 0.3 0.4 29.4 2.6 1.6 1.6 5.5 1.8 1.5 2.8 3.2 1.8 2.7 2.4 2.9 3.4 93.1 0.0 5.1 0.3 42.1 19.5 8.6 15.0 3.4 0.6 2.8 3.4 1.5 0.0 19.1 3.7 52.1 0.7 199.8 129.8 0.0 0.3 0.9 15.9 101.0 41.1 1.8 6.1 1.8 0.2 0.7 18.5 19.4 62.6 3.8 9.9 6.4 2.5 19.8 0.0 19.2 15.0 10.2 38.0 199.2 0.3 0.0 64.5 37.4 23.4 30.4 0.5 89.6 0.5 0.1 7.8 103.7 1.2 786.9 4.0 3.2 0.3 13.0 1.1 0.0 5.3 30.1 0.5 2.3 43.9 41.5 0.7 184.3 1.6 8.7 91.9 PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Early spermatids: 75.6;Inhibitory neurons: 31.9;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Cell line enhanced" "Detected in many" "U-266/84: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" 3.0 4.0 1.8 1.6 2.0 3.5 3.0 3.2 2.0 5.2 4.2 3.2 1.3 6.0 2.8 2.2 4.6 2.4 3.0 1.6 3.2 1.9 0.4 4.2 0.9 4.1 4.0 10.3 4.8 8.6 3.9 3.5 4.0 4.1 2.9 4.7 1.8 4.3 1.6 1.5 1.8 4.4 4.7 2.4 2.1 3.6 2.9 1.4 5.8 3.0 0.8 2.9 3.3 4.4 2.2 3.4 7.8 0.1 4.5 9.3 9.2 4.7 9.9 4.7 4.2 4.4 1.2 0.4 1.2 6.2 4.5 0.1 0.0 1.0 6.0 0.0 1.4 2.9 3.1 0.3 4.9 10.0 0.1 6.6 2.9 3.3 4.1 4.3 3.4 1.2 0.0 14.2 5.7 0.4 1.5 0.1 5.7 0.8 2.7 0.0 9.3 6.1 1.6 0.0 1.4 6.2 0.0 0.1 0.9 4.0 6.4 4.1 1.4 0.2 2.7 4.8 4.6 13.0 19.7 0.1 3.6 0.1 3.6 0.1 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 1.8 2.0 3.2 2.0 1.6 3.2 4.1 4.0 4.0 4.7 2.9 4.4 7.1 12.8 5.6 51.2 0.5 1.7 2.7 2.4 9.1 9.1 1.1 2.4 8.2 2.8 3.8 1.8 8.4 1.0 0.2 1.5 1.9 2.3 75.6 1.4 9.4 6.3 3.6 0.0 25.0 2.5 2.6 9.6 2.6 1.4 2.5 15.5 3.6 0.0 0.8 0.0 31.9 3.6 4.1 0.3 0.7 31.0 8.7 0.6 1.8 23.4 0.2 7.6 0.0 52.8 8.0 1.5 0.8 9.4 0.7 2.6 0.1 0.2 1.8 7.5 6.6 10.1 6.6 8.2 3.5 4.6 1.7 0.5 1.2 14.9 3.0 0.7 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8;Excitatory neurons: 307.7;Inhibitory neurons: 122.2;Microglial cells: 64.6;Oligodendrocyte precursor cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Cell line enriched" "Detected in many" 18 "HBEC3-KT: 1015.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" 6.3 3.0 3.7 5.2 5.0 1.7 5.0 0.0 7.2 12.5 0.0 4.2 2.6 12.1 1.6 2.4 6.4 10.0 13.8 4.2 0.0 5.0 1.7 9.5 4.6 0.1 1.3 12.5 2.0 1.4 2.0 5.3 0.0 5.1 2.2 4.2 7.8 5.6 3.9 4.7 2.4 12.7 0.0 14.8 2.9 6.0 3.9 1.6 7.9 4.6 3.4 5.5 6.3 1.0 7.7 4.4 17.0 0.5 12.4 13.1 0.5 11.0 5.2 3.0 5.1 0.5 16.0 0.5 31.4 1.6 0.0 2.9 12.5 1015.4 3.5 0.6 6.4 17.5 0.9 0.4 1.7 0.3 0.2 19.3 7.5 12.7 1.7 1.8 39.7 0.3 1.8 3.1 2.9 0.3 0.1 0.5 56.1 0.1 18.0 0.2 0.7 0.1 21.1 0.7 4.4 3.0 0.3 0.7 0.7 13.7 0.3 35.1 2.9 0.9 13.4 14.0 14.2 0.9 0.6 6.1 0.2 10.7 0.6 2.6 1.8 0.4 0.2 1.0 0.7 7.6 0.2 0.2 1.0 11.5 0.4 0.2 2.4 0.5 0.6 1.6 0.2 0.9 3.7 5.0 0.0 7.2 4.2 0.0 0.1 1.3 0.0 0.0 3.9 1.0 6.9 16.0 8.2 8.8 13.2 2.7 5.3 7.3 4.0 13.5 4.0 2.2 5.7 14.3 2.6 1.8 2.1 0.6 0.2 0.0 0.0 3.8 72.8 5.2 43.0 8.1 0.0 0.4 307.7 2.6 0.2 19.2 3.6 8.6 1.3 59.1 14.6 0.1 0.6 8.4 122.2 0.0 2.0 0.9 2.3 25.4 9.9 1.2 7.2 64.6 1.1 2.7 0.0 114.6 5.3 3.9 0.1 24.8 3.1 1.0 0.0 3.3 0.3 4.5 0.0 3.8 7.9 5.1 4.8 1.9 1.4 0.7 1.1 18.6 0.0 0.8 PRICKLE3 LMO6 ENSG00000012211 "Prickle planar cell polarity protein 3" O43900 X 49174802-49186528 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 60.8;Late spermatids: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA000998 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA000998: AB_1079258" "unprognostic (9.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.97e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-2)" "unprognostic (3.78e-2)" "unprognostic (1.14e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (2.28e-3)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.84e-5)" 4.3 3.8 2.3 3.5 2.5 2.1 4.0 2.5 2.9 4.8 4.2 3.7 3.0 4.0 1.7 10.2 4.7 2.9 5.7 2.1 2.4 2.5 3.1 4.0 3.3 2.7 2.7 2.6 5.1 4.0 2.1 3.8 2.7 4.6 3.0 0.6 4.5 5.8 11.6 12.0 3.5 3.3 2.9 3.8 4.0 1.1 2.7 3.4 3.9 10.5 4.5 5.1 6.6 3.0 17.7 20.3 0.5 1.7 8.4 9.1 19.0 6.8 10.2 5.1 7.9 6.2 10.9 0.0 6.1 8.4 1.6 24.8 15.6 25.1 2.3 21.9 8.4 7.4 12.2 4.7 12.2 5.0 24.3 8.3 19.3 6.4 15.7 3.3 5.3 4.5 12.4 6.6 8.6 27.8 6.0 7.4 3.0 10.6 21.7 8.3 5.3 9.8 6.7 24.7 3.4 0.0 9.4 8.6 6.7 6.0 17.4 5.6 6.2 0.1 8.0 7.2 2.6 11.6 8.3 4.1 8.0 6.6 0.1 2.4 8.3 9.2 2.3 9.1 3.2 7.0 3.1 3.8 7.5 4.1 2.5 2.6 4.7 3.0 12.1 3.5 4.2 5.1 2.3 2.5 2.5 2.9 2.1 2.4 2.7 2.7 2.7 2.9 2.7 3.0 2.7 0.0 1.5 1.0 4.2 15.2 5.5 13.7 10.8 0.3 1.4 2.2 1.5 0.0 6.6 1.8 2.1 3.2 1.0 1.9 1.9 3.4 60.8 2.7 2.0 3.2 1.2 2.5 0.2 2.7 6.8 2.8 6.6 2.4 0.0 1.7 1.4 1.4 2.5 0.0 0.1 3.3 8.2 1.3 8.1 100.8 1.5 2.8 8.8 0.0 2.9 0.9 1.0 2.0 1.0 2.2 2.7 0.7 3.2 4.8 1.7 2.0 3.3 0.2 0.0 1.5 2.6 0.4 0.5 15.9 19.0 3.3 2.2 2.2 2.5 4.6 PRIM2 PRIM2A ENSG00000146143 "DNA primase subunit 2" P49643 6 57314805-57646850 "Plasma proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 30.6" "Cell type enhanced" "Detected in many" "Microglial cells: 70.3;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046566 Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA046566: AB_2679701" "unprognostic (1.24e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (3.08e-1)" "unprognostic (6.24e-2)" "prognostic unfavorable (3.44e-5)" "unprognostic (2.31e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.00e-5)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.89e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (2.04e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" 4.3 3.3 3.9 6.6 4.6 15.0 6.9 6.0 4.3 5.6 6.9 6.9 6.0 7.2 6.9 4.3 6.2 4.3 3.3 3.9 5.6 3.9 5.0 4.8 10.6 4.2 4.7 7.2 4.0 3.9 1.9 7.5 4.4 30.6 8.4 4.0 4.2 5.6 2.3 5.8 5.2 8.0 2.8 5.5 4.8 6.5 4.5 15.3 4.4 2.4 11.8 5.8 4.1 7.1 44.8 17.7 34.1 37.6 16.8 29.5 27.3 53.1 48.8 57.0 74.7 26.6 21.1 39.4 27.7 66.6 39.6 27.9 30.2 29.2 71.6 35.1 24.2 47.6 22.7 43.0 7.3 43.5 27.4 12.1 12.0 61.0 20.3 14.2 26.9 44.1 46.2 38.9 48.3 28.2 49.8 37.6 22.0 37.1 17.2 34.7 46.9 31.2 21.0 20.7 24.5 19.2 31.5 15.9 21.3 38.9 33.3 47.4 17.9 54.7 55.5 106.2 44.2 14.4 29.3 47.2 26.6 50.5 30.4 0.7 1.9 1.8 4.1 3.7 4.3 3.5 3.5 5.4 3.0 4.0 2.8 5.7 1.4 5.2 4.2 5.1 4.7 2.1 3.9 4.6 6.0 4.3 3.9 5.6 4.2 4.7 4.4 2.8 4.5 7.1 5.9 0.0 2.7 30.0 11.2 4.0 6.7 4.1 11.4 5.6 6.2 4.2 1.1 2.8 4.6 3.7 12.5 17.0 15.1 4.3 3.9 5.1 10.3 4.9 7.1 5.0 1.2 26.5 38.0 5.2 22.0 6.9 4.1 6.0 12.0 13.7 4.2 3.5 9.3 6.7 32.6 6.5 10.2 6.6 6.4 3.7 6.5 7.0 0.0 70.3 7.3 4.8 17.5 56.8 54.5 4.9 5.3 6.8 12.7 7.1 4.4 1.8 4.1 5.6 19.7 4.9 6.8 10.1 11.2 8.7 3.0 5.7 13.6 8.0 8.6 5.3 PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556124-151877125 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 143.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 208.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 178.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.46e-2)" "unprognostic (9.29e-2)" "unprognostic (1.76e-1)" "unprognostic (4.33e-3)" "unprognostic (7.13e-2)" "unprognostic (8.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.80e-1)" "unprognostic (3.61e-2)" "unprognostic (4.52e-1)" 27.1 7.7 21.7 12.8 20.3 8.1 18.4 16.7 22.8 16.2 11.1 25.8 24.4 19.8 14.3 16.2 17.9 12.8 143.0 23.7 21.1 22.5 36.1 14.2 11.6 19.3 17.4 10.9 10.9 9.2 9.5 16.1 19.7 25.3 18.9 2.9 15.0 19.5 15.0 13.5 26.2 16.5 15.8 17.6 26.7 12.8 18.5 7.9 16.6 21.7 9.8 47.9 17.5 19.6 46.6 13.6 9.1 10.6 36.4 28.6 14.4 21.5 19.5 22.7 22.3 8.6 52.5 0.0 34.0 28.9 178.2 13.9 5.7 22.4 30.0 15.8 6.2 11.5 1.8 0.9 60.8 8.5 11.4 16.5 49.7 21.8 21.0 34.1 40.2 14.9 4.1 5.6 66.2 17.2 3.5 6.7 9.7 18.8 37.5 5.6 6.9 9.7 39.2 10.9 38.5 6.7 10.7 19.9 10.0 22.9 4.0 13.6 52.8 5.0 4.3 2.8 13.1 3.5 5.1 0.0 63.5 29.8 45.9 26.2 9.3 10.9 5.3 7.0 4.1 9.6 4.9 4.8 6.5 4.0 4.8 7.3 11.1 4.4 6.4 6.0 2.9 5.3 21.7 20.3 16.7 22.8 23.7 21.1 19.3 17.4 19.7 15.8 18.5 19.6 19.2 6.4 19.8 37.5 24.8 10.6 39.9 25.0 19.9 22.3 20.6 14.5 122.3 8.6 22.9 46.0 8.4 3.9 43.8 29.5 64.6 14.1 49.3 75.1 16.9 20.4 13.1 3.8 208.5 22.7 31.2 24.9 21.9 98.1 22.2 4.6 18.9 76.8 17.7 3.3 85.2 34.5 105.8 57.2 48.2 35.8 7.5 50.9 16.0 73.1 62.9 14.7 37.0 39.2 4.4 27.5 21.9 7.9 23.4 45.7 77.7 19.7 14.2 6.1 13.1 6.9 27.3 4.0 32.3 12.8 10.9 50.6 27.3 5.0 28.0 45.2 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 110.2;Excitatory neurons: 146.3;Granulosa cells: 712.1;Theca cells: 271.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 70.7;Daudi: 99.8;K-562: 61.4;U-698: 254.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 135.8 44.9 10.7 4.8 12.1 14.2 51.3 5.7 17.5 8.0 5.3 11.1 3.6 6.9 4.4 11.2 7.0 4.9 15.5 13.2 9.5 8.8 2.5 7.6 3.8 6.2 10.2 26.4 8.7 6.5 11.4 15.1 8.3 9.2 6.9 7.5 9.9 4.4 1.5 3.7 11.5 5.1 6.9 16.7 9.1 13.6 7.8 2.6 3.5 6.1 4.0 20.3 6.2 10.1 0.1 1.5 9.1 70.7 36.8 0.0 0.1 3.6 11.5 3.0 2.7 0.0 0.2 99.8 0.8 2.3 8.6 0.1 7.1 0.0 5.5 2.8 7.9 33.3 0.1 0.0 10.3 0.6 4.5 0.5 0.0 0.3 0.0 3.1 42.9 5.4 61.4 2.9 0.1 7.5 14.0 0.4 17.3 0.0 2.8 4.0 0.2 0.0 0.1 0.1 11.6 16.7 5.4 1.2 3.9 22.9 2.1 7.0 24.4 3.5 9.2 0.0 7.1 2.1 0.1 254.8 2.5 17.5 33.9 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 10.7 12.1 5.7 17.5 13.2 9.5 6.2 10.2 8.3 6.9 7.8 10.1 39.6 3.2 1.5 9.8 1.9 2.4 1.6 2.1 0.6 33.5 27.9 10.5 35.9 12.8 5.1 7.3 10.4 0.1 3.7 1.7 0.0 2.5 7.9 1.8 16.2 17.4 0.0 110.2 146.3 0.0 0.6 17.5 3.6 0.9 4.5 712.1 19.2 0.0 1.6 5.0 71.9 1.9 4.1 19.6 26.4 8.5 29.8 64.1 17.8 15.9 17.0 6.4 3.1 60.8 10.9 0.1 2.1 53.0 2.0 3.5 0.0 0.8 5.4 11.9 19.7 5.4 57.7 2.5 6.5 0.7 2.4 0.0 3.7 271.7 2.7 4.6 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB034225: AB_1564157, HPA055687: AB_2682886" "unprognostic (6.75e-3)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (7.06e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-3)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (9.31e-3)" "unprognostic (2.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" 9.0 7.7 4.7 11.1 5.1 25.5 9.1 7.0 6.2 7.6 4.4 12.8 10.6 9.0 9.0 11.6 7.2 6.0 8.9 4.8 4.3 9.0 9.5 12.2 13.4 6.7 5.2 6.9 15.5 5.7 7.7 21.0 5.9 10.6 13.7 9.9 13.6 6.2 10.1 15.8 12.4 7.8 5.1 12.8 10.9 12.7 5.0 14.0 10.0 7.2 14.6 8.5 9.4 6.9 16.0 12.2 37.3 25.9 12.5 10.0 59.1 14.8 13.0 14.6 15.5 39.0 24.3 37.1 11.7 14.5 19.7 26.9 40.5 26.6 23.8 56.6 33.1 54.7 13.4 27.1 28.5 57.7 32.4 13.3 31.4 23.2 52.3 9.0 24.2 41.9 27.6 21.8 15.7 27.8 35.2 30.6 55.8 31.4 13.0 36.6 39.6 23.3 14.6 24.6 21.0 24.2 10.4 26.8 21.7 28.9 28.8 32.9 22.2 8.4 13.5 16.7 18.9 20.2 22.6 39.7 13.6 31.5 16.8 4.6 1.9 0.4 2.8 1.6 3.1 2.0 2.8 3.0 2.2 1.4 2.4 2.6 0.5 4.2 2.5 2.5 1.7 2.7 4.7 5.1 7.0 6.2 4.8 4.3 6.7 5.2 5.9 5.1 5.0 6.9 9.5 3.2 15.3 13.7 11.7 7.0 5.2 4.6 8.0 11.7 8.4 7.6 6.2 5.7 5.6 0.0 8.4 19.3 19.4 12.7 1.9 7.3 16.8 9.0 9.4 10.0 11.4 6.3 16.8 13.5 18.5 6.4 11.2 12.1 12.0 12.5 8.6 6.0 10.4 16.8 12.7 16.3 0.0 16.3 8.0 5.6 6.5 9.9 5.4 12.2 9.9 4.5 13.4 14.1 27.3 15.0 19.2 4.9 16.9 11.2 6.5 3.6 6.0 9.5 0.0 7.8 7.2 14.0 11.6 10.5 7.2 26.8 11.5 5.2 14.8 8.1 PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "retina: 641.4" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 260.6;Rod photoreceptor cells: 482.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.0;ASC TERT1: 3.4;fHDF/TERT166: 5.3;HHSteC: 7.8;HSkMC: 6.0;LHCN-M2: 3.5" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" 1.1 0.8 2.1 0.5 1.5 0.0 0.5 0.4 1.8 2.0 0.1 2.2 0.4 2.1 1.8 0.7 1.3 1.1 1.5 3.1 2.1 1.4 0.2 1.5 0.1 0.9 1.0 3.1 2.3 4.3 2.5 0.9 1.2 1.5 0.8 641.4 0.7 1.1 13.2 0.3 1.4 1.9 0.4 0.8 1.2 3.7 2.7 0.2 4.1 2.9 0.1 1.2 1.1 1.2 0.0 0.0 0.0 0.0 3.0 3.4 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 7.8 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.2 0.0 0.1 0.0 2.1 1.5 0.4 1.8 3.1 2.1 0.9 1.0 1.2 0.4 2.7 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 39.3 0.1 0.0 0.9 0.0 0.1 0.0 260.6 0.1 0.0 0.0 3.9 0.3 0.2 0.1 0.9 2.3 0.0 0.0 2.3 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.4 0.2 0.0 11.8 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.9 0.0 42.6 1.0 0.5 0.6 0.5 0.0 1.9 0.0 0.2 0.0 0.2 0.0 482.7 0.0 0.9 0.8 2.3 0.5 0.1 0.3 0.1 0.0 1.3 0.0 0.1 PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.3;Basal squamous epithelial cells: 145.1;Prostatic glandular cells: 153.9;Squamous epithelial cells: 141.8;Suprabasal keratinocytes: 141.5;Urothelial cells: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Cell line enhanced" "Detected in many" "HaCaT: 52.7;hTCEpi: 28.0;SK-BR-3: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" 1.1 1.6 0.7 2.0 0.9 4.6 7.2 0.7 0.8 7.5 2.1 6.9 7.5 1.4 6.1 23.4 5.4 3.4 1.3 0.7 1.5 13.3 22.6 6.4 1.1 1.1 0.9 0.3 3.9 2.9 2.8 5.8 1.1 6.3 6.3 0.2 10.0 6.0 1.1 20.8 7.4 0.9 0.7 3.0 5.4 0.5 1.0 3.6 5.5 1.4 6.6 6.8 13.7 1.3 13.2 0.4 0.1 0.1 0.3 0.0 5.4 0.1 6.5 1.5 2.6 6.2 12.7 0.1 0.4 0.0 3.3 52.7 1.3 3.2 0.4 0.4 8.7 2.7 1.8 0.4 0.0 0.9 2.4 0.4 28.0 0.5 0.1 2.2 0.0 0.0 0.0 0.7 0.5 5.9 1.1 6.0 0.6 10.7 1.5 0.1 0.0 1.6 9.6 16.5 1.8 0.1 8.8 22.0 2.8 1.6 16.0 12.8 0.1 0.6 0.8 2.9 1.3 5.8 4.3 0.1 1.6 7.5 2.5 0.8 2.3 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 0.2 0.1 0.1 11.9 0.2 0.8 0.2 0.1 0.5 0.7 0.9 0.7 0.8 0.7 1.5 1.1 0.9 1.1 0.7 1.0 1.3 4.2 28.9 23.0 1.0 2.8 124.3 92.5 53.6 145.1 0.1 43.0 21.1 1.0 95.8 33.9 47.8 0.0 24.4 1.7 46.8 7.9 31.5 0.7 75.5 7.4 10.2 13.8 2.5 0.3 36.3 16.8 3.6 25.0 81.9 0.0 6.0 8.9 57.1 8.1 1.7 0.3 34.7 24.4 50.0 15.4 0.3 0.3 12.6 12.4 4.7 40.2 0.1 0.0 1.0 0.1 26.4 19.5 1.5 6.9 153.9 48.3 21.4 51.1 0.2 6.6 2.5 8.8 2.4 4.1 141.8 141.5 82.0 2.6 0.2 47.0 167.4 PRRT1B "DSPD2, IFITMD8" ENSG00000283526 "Proline rich transmembrane protein 1B" A0A1B0GWB2 9 131545514-131558620 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 6.4;lung: 4.1;pancreas: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A549: 14.7;BEWO: 9.6;MCF7: 3.9;T-47d: 7.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" 0.0 0.0 0.2 0.0 0.9 0.0 0.2 0.6 0.5 0.5 0.1 1.4 0.4 0.2 0.0 0.0 6.4 0.7 0.0 0.1 0.1 0.5 2.9 4.1 0.0 0.2 0.2 0.0 4.2 1.5 0.1 0.0 0.1 2.5 1.6 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.7 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.1 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.1;Oligodendrocyte precursor cells: 111.6;Oligodendrocytes: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cell line enhanced" "Detected in many" "CACO-2: 75.9;CAPAN-2: 94.3;HEL: 56.2" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" 5.4 22.2 21.7 4.5 28.7 0.9 7.6 24.9 27.2 12.9 16.1 9.9 17.7 15.8 7.4 5.5 9.8 14.8 10.9 22.4 24.6 4.8 2.8 4.3 4.2 26.7 24.0 20.2 4.6 13.4 11.4 2.9 28.0 7.8 11.3 16.5 9.7 8.2 1.3 1.8 17.1 9.8 25.8 3.2 17.5 2.2 23.7 6.8 5.3 2.8 3.2 7.4 6.3 37.1 19.5 41.3 30.2 12.4 4.9 24.4 0.0 20.2 15.1 14.2 19.3 75.9 94.3 0.0 3.1 23.7 1.2 10.7 34.7 0.0 22.0 0.0 1.4 56.2 7.6 0.1 14.6 0.0 0.0 7.1 0.2 7.7 0.0 13.3 22.6 2.2 18.6 10.5 6.8 0.5 8.8 0.1 20.9 3.3 0.7 9.7 0.1 0.2 12.7 0.5 21.5 0.9 19.3 0.1 0.0 0.6 1.1 4.3 12.2 6.3 15.5 23.1 12.2 0.9 0.0 0.0 16.8 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 4.4 0.0 0.1 0.0 0.9 21.7 28.7 24.9 27.2 22.4 24.6 26.7 24.0 28.0 25.8 23.7 37.1 3.5 0.0 0.5 136.1 0.7 2.7 4.6 5.4 2.8 10.2 1.1 5.8 8.6 7.2 3.9 3.7 2.1 1.0 0.8 3.8 5.9 5.8 1.4 1.5 27.3 2.8 5.4 3.0 38.2 0.5 4.9 20.6 12.2 2.2 0.0 25.1 7.5 0.1 7.2 6.7 43.0 7.3 0.0 0.9 3.1 1.0 12.2 7.8 3.6 24.4 1.5 45.8 0.0 111.6 148.2 2.3 2.1 9.8 1.3 1.1 12.2 0.1 1.1 15.9 0.0 16.4 10.4 3.4 6.3 0.4 2.8 0.8 1.0 22.7 11.6 1.5 PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.6;intestine: 110.9" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 918.7" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 51.1;LHCN-M2: 83.2;RH-30: 71.5;RPTEC TERT1: 40.1" "Low region specificity" "Detected in all" "HPA022470, HPA031079" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Nucleoplasm, Nucleoli" "HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" 11.3 23.2 26.9 11.9 82.9 2.9 5.2 49.5 54.7 16.6 0.0 110.9 7.1 50.6 18.5 34.0 29.4 16.4 8.9 26.9 48.4 15.4 1.9 5.1 2.8 90.0 52.8 4.7 4.3 4.0 30.9 4.0 76.4 47.6 18.5 39.0 14.6 64.8 16.7 5.4 27.7 55.3 31.7 4.4 37.1 4.9 53.1 0.9 2.6 56.8 2.5 69.2 14.4 120.6 0.0 0.0 1.5 0.0 51.1 25.8 0.2 1.8 3.6 6.6 14.7 0.4 0.0 0.3 3.9 4.5 13.6 0.0 0.1 0.0 18.0 0.4 2.9 6.3 3.7 0.0 8.5 0.1 0.3 28.7 0.1 26.7 0.7 15.1 14.4 0.4 0.0 20.8 83.2 0.1 4.6 1.8 4.0 0.0 0.0 0.5 71.5 0.3 40.1 0.0 17.4 0.0 0.0 0.3 4.9 2.8 0.1 0.7 11.9 14.2 0.7 34.9 1.2 22.2 3.2 0.0 11.5 0.3 0.0 0.3 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.2 26.9 82.9 49.5 54.7 26.9 48.4 90.0 52.8 76.4 31.7 53.1 120.6 0.4 0.0 1.1 27.7 0.0 2.3 0.4 0.5 0.0 47.5 1.2 3.4 11.1 0.0 1.0 11.0 0.0 0.0 1.6 3.5 1.9 0.0 12.6 37.7 4.7 3.7 54.3 0.0 152.4 0.5 0.2 2.9 3.1 34.7 0.0 0.1 21.8 0.2 3.2 15.2 65.4 36.4 4.1 3.1 3.1 30.0 0.9 2.3 5.4 13.1 1.7 9.9 2.1 134.7 918.7 0.4 8.8 1.5 0.1 5.1 9.9 20.3 17.0 6.5 0.0 27.2 9.6 4.3 4.2 0.0 1.4 0.0 0.7 0.5 5.2 0.6 PSD4 "EFA6B, TIC" ENSG00000125637 "Pleckstrin and Sec7 domain containing 4" Q8NDX1 2 113157325-113209396 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 51.2;Proximal enterocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 9.8;NB-4: 9.3" "Low region specificity" "Detected in single" "HPA034722, HPA077847" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA034722: AB_10669730, HPA077847: " "unprognostic (1.87e-3)" "unprognostic (1.32e-2)" "unprognostic (2.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.21e-2)" "unprognostic (1.13e-3)" "prognostic favorable (9.91e-5)" "unprognostic (6.56e-2)" "unprognostic (4.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-2)" "prognostic favorable (4.00e-4)" "unprognostic (8.12e-2)" "unprognostic (2.41e-1)" "unprognostic (3.60e-3)" 1.7 13.7 1.4 3.1 1.3 3.7 3.9 0.5 1.2 2.3 0.7 7.0 2.0 0.7 4.0 10.8 1.7 1.3 0.8 1.0 1.0 5.2 21.2 5.8 3.9 1.0 0.8 0.5 11.6 3.0 3.4 0.9 1.1 8.7 1.9 0.5 11.3 1.2 0.6 9.0 17.7 0.4 0.9 23.3 12.4 1.5 1.5 5.9 10.1 0.3 4.0 3.7 4.2 0.9 5.7 1.0 0.3 0.1 0.0 0.0 6.1 0.4 2.2 0.4 0.5 1.5 8.1 9.8 1.2 0.2 1.7 7.4 0.0 2.0 0.1 8.3 0.1 4.1 0.8 2.2 0.1 6.9 6.9 0.1 1.9 0.2 0.5 0.9 0.0 3.8 3.9 4.1 0.0 3.2 7.1 9.3 0.1 1.8 1.1 0.1 0.1 4.3 0.4 1.4 0.5 0.0 0.7 5.1 0.0 0.2 1.6 5.6 0.1 0.3 0.2 0.2 1.6 5.0 4.0 3.0 0.9 3.3 0.1 1.7 0.9 1.7 2.0 0.6 1.7 1.0 1.5 1.8 0.6 1.2 1.7 1.9 3.9 2.4 0.7 1.5 1.1 1.4 1.4 1.3 0.5 1.2 1.0 1.0 1.0 0.8 1.1 0.9 1.5 0.9 0.9 19.2 12.0 7.5 28.6 12.7 10.4 7.6 13.1 0.3 22.5 11.2 1.8 11.5 5.8 33.1 0.0 20.7 41.6 39.1 0.0 21.3 0.3 9.0 1.6 2.1 7.2 13.0 0.9 23.6 11.2 3.0 31.1 20.4 3.8 2.9 2.9 51.2 12.1 3.3 1.7 10.7 4.1 13.8 17.0 0.9 0.9 14.3 1.8 2.8 13.8 10.1 47.4 2.5 0.2 23.1 17.8 0.0 18.3 15.8 50.3 7.1 4.6 0.4 0.0 3.0 1.7 0.2 1.1 17.4 15.8 7.5 28.2 1.7 18.6 11.1 PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 860.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" 32.9 40.9 67.8 46.9 72.1 62.0 27.4 83.9 89.1 45.8 52.6 40.8 23.1 57.5 36.0 26.2 42.9 30.8 34.4 71.5 79.2 32.6 22.3 32.8 80.7 65.2 66.4 86.0 17.1 30.3 52.2 39.5 64.4 36.3 30.9 154.4 19.1 41.0 38.6 26.0 34.4 43.2 65.1 54.7 28.5 81.6 68.1 129.7 37.1 29.5 69.3 31.2 32.3 72.2 117.5 76.5 254.7 187.4 54.0 65.2 56.7 138.3 98.1 121.7 143.6 32.1 59.5 248.1 31.4 73.5 68.2 32.0 160.1 75.0 174.9 164.8 96.6 860.4 194.9 60.8 65.1 101.7 91.7 54.8 21.0 102.1 74.4 121.0 108.0 115.2 144.4 134.1 80.2 42.8 211.5 250.9 395.2 2.7 117.2 194.7 138.8 50.7 68.3 40.5 161.1 176.7 123.7 54.0 67.1 157.5 54.5 134.9 76.7 88.0 88.6 66.7 133.2 57.1 85.3 221.8 70.2 100.8 51.6 13.7 2.6 5.4 6.1 2.0 7.7 11.0 12.5 8.8 3.0 17.5 18.7 11.6 8.4 9.5 5.7 3.1 12.9 2.4 67.8 72.1 83.9 89.1 71.5 79.2 65.2 66.4 64.4 65.1 68.1 72.2 93.7 54.5 31.9 27.4 98.1 31.9 49.1 8.1 48.9 231.0 22.0 35.6 57.8 31.5 23.1 47.8 66.7 122.7 82.1 24.7 62.6 9.5 95.5 92.9 62.5 84.8 38.1 160.1 73.4 8.5 76.2 74.8 23.0 35.1 15.2 104.2 65.3 18.0 32.1 138.0 76.9 34.1 2.0 36.5 45.9 58.5 125.9 45.8 40.9 20.6 47.9 162.2 83.4 49.8 67.6 3.6 20.6 134.3 60.4 19.6 14.1 54.5 42.1 279.1 124.9 85.2 89.8 217.9 243.8 34.5 21.2 41.3 111.6 68.6 45.8 20.3 PSMC3 "TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: AB_1079706" "unprognostic (2.01e-2)" "unprognostic (5.08e-3)" "unprognostic (9.43e-2)" "unprognostic (8.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.71e-2)" "unprognostic (8.99e-3)" "unprognostic (1.63e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" 85.3 86.1 106.8 64.7 117.3 96.1 77.9 105.3 131.0 73.7 105.8 110.2 52.2 89.9 62.5 88.7 69.0 44.0 172.1 107.8 106.3 73.8 117.7 76.2 65.3 108.6 114.7 58.2 81.4 74.1 55.4 78.8 111.0 74.2 59.1 30.9 73.0 69.8 292.0 103.4 64.0 77.5 104.6 67.8 87.7 74.7 115.2 90.6 69.4 162.9 76.5 80.8 71.7 107.0 223.7 248.2 233.5 173.3 109.6 117.3 226.5 181.5 267.4 445.7 313.8 223.3 126.8 179.5 110.1 230.1 195.7 218.3 206.7 237.7 199.0 269.4 268.1 173.1 301.1 218.5 141.4 203.7 177.0 131.4 126.1 181.6 202.5 98.4 253.8 182.7 249.2 164.7 276.0 497.0 259.5 258.4 229.5 280.7 296.1 269.3 458.8 157.3 209.5 165.2 170.0 147.1 148.7 206.9 116.2 98.2 255.7 209.8 181.3 253.7 321.1 363.8 474.7 176.5 220.0 209.2 262.4 201.7 325.1 111.5 154.3 121.8 160.8 194.6 146.7 146.8 132.9 147.8 160.6 122.4 116.5 118.6 33.9 173.3 211.6 160.0 191.0 254.7 106.8 117.3 105.3 131.0 107.8 106.3 108.6 114.7 111.0 104.6 115.2 107.0 81.5 57.7 42.0 3.9 59.5 86.3 112.8 198.5 50.7 41.2 61.4 64.1 217.6 81.5 103.7 68.0 16.7 265.9 60.0 143.9 152.6 199.2 152.5 72.0 75.7 96.0 64.5 136.6 6.4 202.6 257.9 100.4 54.0 70.1 75.3 79.2 77.1 144.2 158.2 37.0 5.3 111.5 75.3 62.4 80.0 217.6 88.6 62.5 99.6 1.9 132.0 120.2 74.2 3.0 5.2 214.2 110.8 100.1 96.3 102.8 127.7 191.3 76.9 47.4 118.3 75.1 193.3 147.0 63.6 51.3 77.3 352.9 61.8 74.1 117.6 101.6 PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 60.0;Enteroendocrine cells: 60.0;Hofbauer cells: 42.5;Kupffer cells: 41.8;Macrophages: 41.8;monocytes: 51.1;NK-cells: 91.6;T-cells: 68.4;Theca cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 55.1;HL-60: 14.4;NB-4: 20.9;THP-1: 14.7;U-937: 59.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" 6.0 2.6 2.8 11.7 2.7 56.6 2.3 2.7 3.1 2.0 3.4 3.3 2.5 1.6 0.1 2.0 3.1 2.9 2.4 2.7 2.8 3.4 3.4 10.4 13.5 3.1 3.1 1.0 1.3 0.2 1.6 1.8 3.0 2.9 0.8 0.1 2.4 1.0 1.5 1.8 9.4 1.4 3.1 33.9 2.9 0.7 3.6 4.2 2.9 1.0 5.5 4.3 2.7 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 55.1 0.0 0.0 0.0 3.3 0.0 14.4 0.1 0.2 0.1 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 20.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 4.0 0.6 0.0 0.1 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.1 0.0 0.0 1.3 2.4 0.1 59.8 0.0 4.8 71.5 71.4 39.9 33.5 30.8 13.3 27.2 32.7 59.0 18.5 14.3 22.3 85.3 41.6 38.3 5.2 27.0 42.2 2.8 2.7 2.7 3.1 2.7 2.8 3.1 3.1 3.0 3.1 3.6 3.1 1.1 0.0 5.1 1.0 19.2 9.3 1.2 0.4 0.0 1.1 0.9 1.1 1.9 0.0 2.5 0.0 0.0 0.3 60.0 3.1 0.0 0.0 9.6 0.3 0.3 0.8 60.0 4.8 0.4 0.2 0.7 1.9 0.0 0.3 2.5 0.1 2.2 0.9 42.5 0.0 0.1 6.1 2.0 41.8 36.5 18.6 0.9 41.8 7.2 0.0 51.1 0.2 91.6 5.5 1.0 0.1 2.5 2.6 8.5 0.3 0.3 0.4 0.0 0.4 0.0 0.8 3.1 0.2 1.2 0.2 4.8 0.5 68.4 78.1 0.3 1.2 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTGES3L ENSG00000267060 "Prostaglandin E synthase 3 like" 17 42968088-42980433 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "heart muscle: 41.4;skeletal muscle: 124.3;tongue: 95.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.6;Cone photoreceptor cells: 8.4;Early spermatids: 13.1;Spermatocytes: 8.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "THP-1: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (9.77e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (4.66e-2)" "unprognostic (2.36e-2)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (6.23e-2)" "unprognostic (2.80e-4)" "unprognostic (9.24e-2)" "unprognostic (3.03e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (6.25e-2)" "unprognostic (4.08e-2)" 0.9 0.6 1.9 1.4 3.1 3.0 1.1 2.1 2.8 1.5 1.8 13.2 1.4 8.2 1.4 3.4 2.5 1.6 41.4 1.9 1.5 0.6 0.3 0.7 1.1 1.6 1.5 0.6 0.5 0.4 1.3 0.5 1.8 2.9 2.8 1.7 2.4 3.4 124.3 1.0 2.5 7.2 1.1 0.7 3.4 2.2 1.5 0.6 0.8 95.1 0.9 5.7 1.2 2.4 0.8 0.6 1.9 2.8 0.1 0.3 1.6 1.2 0.5 1.0 0.6 1.7 0.7 0.7 0.5 0.5 1.0 1.6 1.4 1.5 1.9 0.5 0.7 4.3 3.1 3.1 0.1 0.8 7.1 0.5 1.1 2.2 1.8 0.7 0.3 3.1 1.8 1.4 2.1 0.7 2.8 2.1 1.8 2.2 0.6 1.4 6.3 0.7 1.7 1.5 1.5 4.9 1.3 3.4 2.0 2.2 1.9 16.7 0.4 2.0 1.8 0.6 1.2 3.0 2.1 0.8 0.3 1.0 0.7 0.9 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.5 0.3 0.1 4.1 0.1 0.4 1.9 3.1 2.1 2.8 1.9 1.5 1.6 1.5 1.8 1.1 1.5 2.4 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.8 1.5 1.3 45.6 0.0 0.1 0.0 8.4 0.1 2.9 1.4 0.0 1.4 13.1 1.2 0.4 1.0 1.8 0.0 0.0 0.2 0.6 2.4 0.0 1.1 0.0 0.8 0.7 0.1 1.1 0.0 0.0 0.9 0.0 0.6 0.7 4.5 0.6 2.1 0.0 0.0 1.7 0.8 1.0 0.0 0.0 0.7 2.8 0.4 0.0 0.7 1.1 0.5 0.9 2.6 0.0 2.7 2.5 8.2 3.4 0.0 0.0 0.1 0.2 4.8 1.1 0.3 PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in many" "Club cells: 14.3;Fibroblasts: 22.7;Inhibitory neurons: 10.4;Langerhans cells: 10.6;Microglial cells: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "ASC TERT1: 271.2;HSkMC: 85.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" 9.9 3.4 0.6 5.7 0.4 0.0 7.2 0.1 1.8 4.6 0.3 2.0 1.0 17.9 2.4 0.9 4.6 6.9 1.7 1.9 2.7 3.9 1.3 2.5 1.2 0.7 0.5 4.6 0.9 0.0 0.2 8.1 1.8 3.1 2.7 0.2 4.7 2.0 2.1 5.2 2.4 16.7 0.4 0.6 1.6 1.4 3.5 0.1 0.8 20.1 4.3 11.9 4.4 0.2 0.0 0.0 1.0 0.0 26.5 271.2 0.0 20.5 20.0 7.0 2.7 0.0 0.0 0.0 0.0 12.4 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 85.7 0.0 1.8 17.6 18.3 0.1 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.1 0.0 15.9 0.0 0.0 0.0 2.4 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 5.9 8.5 4.7 2.1 1.6 1.1 0.0 0.0 0.5 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.8 1.9 2.7 0.7 0.5 1.8 0.4 3.5 0.2 1.2 0.0 8.0 0.3 0.0 6.4 0.0 1.0 0.0 1.2 0.2 0.0 0.4 5.7 14.3 9.2 0.0 0.1 0.0 0.0 3.9 4.2 8.5 0.4 0.6 0.6 0.0 0.0 0.4 0.0 0.0 22.7 0.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 10.4 0.0 0.0 0.0 10.6 9.3 5.6 0.4 5.4 17.8 0.0 0.3 0.0 0.0 0.2 0.0 1.1 0.4 0.2 0.1 0.0 0.3 6.3 0.0 6.6 7.1 1.4 1.1 0.2 0.1 4.7 0.3 0.5 0.3 0.0 0.0 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 63.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 26.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 29.4;RPTEC TERT1: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA038343: AB_10671741, HPA046728: AB_2679776" "prognostic unfavorable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 4.0 2.2 7.1 1.7 1.0 0.1 7.5 0.0 2.6 6.6 8.5 9.5 12.4 2.2 17.7 13.2 10.1 2.7 21.1 3.2 5.2 23.0 29.5 5.7 1.1 0.3 14.7 0.6 14.8 10.7 2.9 7.3 1.6 5.9 10.1 2.5 8.5 5.1 63.5 30.1 12.9 1.4 0.4 0.3 9.7 3.2 26.7 3.6 10.1 46.9 4.4 4.2 7.2 0.4 11.1 13.5 0.5 3.5 0.0 0.0 21.1 2.3 0.0 2.9 3.2 7.2 17.7 0.0 2.4 0.1 7.3 25.8 3.7 15.2 2.9 6.2 8.2 0.0 6.2 7.5 0.1 0.0 0.1 0.2 16.0 3.6 7.7 1.2 0.0 4.5 0.0 0.1 0.2 14.0 19.3 3.3 1.6 29.4 10.0 0.1 4.4 0.3 34.0 21.1 8.6 1.8 5.9 21.8 0.0 7.1 12.5 1.8 0.1 1.0 8.2 1.4 0.0 10.4 18.2 0.0 11.2 0.0 7.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 7.1 1.0 0.0 2.6 3.2 5.2 0.3 14.7 1.6 0.4 26.7 0.4 0.4 16.0 28.4 0.7 0.5 11.9 25.9 19.3 4.0 13.4 7.8 8.6 48.6 24.3 24.7 31.3 0.0 23.6 0.1 30.0 17.6 14.5 21.5 27.6 3.1 3.3 13.1 0.0 16.1 19.2 23.7 1.8 15.8 38.4 1.3 0.9 4.6 36.3 2.6 0.0 5.2 18.7 8.2 0.0 1.8 18.5 1.2 0.8 3.6 1.0 0.7 0.3 1.0 0.5 0.6 29.1 24.0 1.9 0.2 26.1 27.9 19.2 28.4 2.2 6.6 3.2 6.0 1.6 10.4 7.0 20.6 10.8 0.8 0.4 18.4 29.0 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 24.2;intestine: 68.6;stomach 1: 23.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.6;Gastric mucus-secreting cells: 60.1;Paneth cells: 94.9;Proximal enterocytes: 113.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 11.8;K-562: 15.0;OE19: 30.9;SK-MEL-30: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042300 Approved Mitochondria NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 1.3 16.9 1.7 3.6 4.4 0.0 0.6 5.2 3.0 0.8 0.9 27.9 67.7 0.7 0.1 0.3 0.5 24.2 1.1 1.7 3.4 0.2 13.3 0.1 0.1 7.1 4.9 0.3 4.6 0.1 5.1 0.1 5.7 0.2 21.2 1.3 0.1 0.0 0.0 0.1 68.6 2.1 3.8 22.2 23.6 0.8 4.8 0.0 0.1 0.0 0.1 5.7 0.6 7.2 6.9 4.2 0.0 1.6 1.3 3.6 0.1 0.1 3.6 0.7 1.4 1.8 9.5 0.0 0.3 0.6 8.2 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.1 4.9 11.8 0.0 4.8 1.0 2.9 2.3 3.6 0.4 0.2 0.0 15.0 0.6 0.0 0.0 0.0 0.3 0.0 30.9 9.8 0.0 0.0 0.5 0.0 0.0 0.4 1.0 0.0 4.2 22.4 0.0 0.0 1.9 0.0 1.0 1.4 0.5 0.1 0.0 3.7 0.0 1.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 4.4 5.2 3.0 1.7 3.4 7.1 4.9 5.7 3.8 4.8 7.2 0.3 0.0 0.0 0.0 0.4 1.8 2.8 1.9 0.0 0.1 0.2 0.3 0.6 21.5 3.8 1.8 0.0 0.0 0.0 123.6 0.0 15.5 0.0 1.2 1.0 0.5 4.8 0.0 0.8 25.8 0.1 1.1 60.1 0.5 0.0 4.1 0.7 5.7 0.2 16.8 0.7 20.8 0.0 0.0 1.1 0.3 0.0 0.4 0.0 1.0 0.6 0.2 1.0 0.0 5.8 26.9 94.9 0.0 0.4 3.4 113.1 0.0 4.5 0.5 0.0 3.1 1.8 0.3 0.2 0.0 1.1 0.1 0.5 3.6 18.7 19.7 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 167.5;Microglial cells: 189.3;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" NA NA 670000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 6.0 3.2 10.2 20.5 13.8 29.5 6.1 6.9 14.9 6.2 18.5 10.2 9.4 2.4 7.8 1.9 4.1 7.1 2.7 10.0 12.7 13.9 11.9 10.0 15.5 9.7 11.7 1.6 6.1 15.8 10.1 7.6 12.4 7.9 8.7 8.1 10.1 7.0 2.4 4.2 14.5 5.9 6.0 23.3 14.6 2.3 18.5 7.0 19.6 2.7 11.0 6.9 2.1 14.7 7.6 28.3 12.1 7.0 1.9 4.1 4.2 7.5 5.5 12.9 9.2 2.0 40.8 6.9 51.8 19.1 19.6 6.0 19.0 2.0 14.9 46.6 5.4 1.9 34.9 2.8 12.1 2.7 41.5 3.2 0.6 3.8 1.0 31.7 7.8 0.5 2.6 4.4 4.7 17.0 0.1 17.3 9.7 25.7 4.4 1.6 1.6 4.0 52.6 11.1 7.9 2.5 20.2 12.0 19.4 8.9 13.0 20.3 25.7 9.9 10.8 20.5 23.4 1.1 1.7 11.4 11.7 8.0 37.3 0.7 1.1 2.8 1.6 2.0 1.0 0.8 0.9 1.2 0.8 0.5 0.7 0.9 9.5 1.0 4.7 1.5 1.0 0.8 10.2 13.8 6.9 14.9 10.0 12.7 9.7 11.7 12.4 6.0 18.5 14.7 1.5 9.6 16.7 43.1 11.3 0.3 9.8 0.8 0.6 13.6 8.3 4.1 3.7 17.2 13.0 38.6 6.2 1.9 32.7 35.5 0.0 7.4 5.5 13.5 2.2 4.5 12.6 3.2 81.0 5.0 0.6 4.0 22.4 22.9 13.9 2.5 5.0 15.6 30.0 10.1 167.5 10.1 2.0 74.2 5.7 8.2 0.3 40.2 1.8 189.3 36.0 10.3 21.6 239.8 167.7 11.8 28.0 0.4 12.9 25.3 37.6 13.5 4.9 1.3 0.0 3.3 4.9 0.2 4.8 0.5 0.3 1.9 22.0 2.3 7.6 8.2 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;pancreas: 98.1" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 131.1;Excitatory neurons: 439.6;Inhibitory neurons: 433.4;Oligodendrocyte precursor cells: 138.2" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 23.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "AF22: 45.5;HDLM-2: 42.0;MOLT-4: 22.1;NB-4: 43.0;SCLC-21H: 23.8;SH-SY5Y: 25.4;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 3.8 16.5 29.4 2.7 34.3 1.3 2.9 0.0 49.9 2.1 0.0 7.7 8.3 3.0 4.2 1.9 10.8 7.6 3.1 35.2 22.7 3.9 1.6 4.8 3.4 7.9 3.1 8.7 98.1 1.0 41.0 2.1 3.4 17.3 6.1 9.2 12.9 3.6 1.2 0.8 6.7 2.1 0.1 13.4 40.2 6.2 14.1 1.6 8.7 1.9 2.5 4.2 2.1 20.5 0.1 0.4 45.5 3.6 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 4.0 0.0 1.2 0.5 9.4 0.3 1.0 0.0 0.0 42.0 0.8 0.0 0.0 7.3 1.1 0.0 0.1 2.0 0.8 0.1 0.5 0.3 0.0 3.4 0.1 0.3 0.0 0.7 22.1 43.0 5.7 13.7 3.2 0.0 2.7 0.2 0.2 0.0 23.8 25.4 0.0 0.1 0.0 0.0 0.0 20.9 6.2 9.2 4.3 0.1 1.5 0.3 0.1 0.0 27.7 17.4 6.8 14.1 1.5 2.8 1.3 0.2 0.5 3.5 2.1 1.4 2.1 4.2 2.4 1.4 23.6 2.4 0.0 0.6 5.3 1.3 29.4 34.3 0.0 49.9 35.2 22.7 7.9 3.1 3.4 0.1 14.1 20.5 40.7 3.2 12.9 16.3 18.4 2.3 12.7 1.3 4.0 30.2 1.9 2.2 3.1 10.0 9.1 40.5 10.4 0.4 8.7 5.9 35.2 22.9 51.9 8.7 2.5 26.3 131.1 6.6 439.6 13.1 0.4 13.0 41.8 0.8 19.0 14.1 44.3 0.8 44.5 11.8 433.4 43.3 6.1 7.0 11.3 19.3 12.5 7.9 12.4 27.2 5.7 67.3 15.5 138.2 11.0 7.3 7.0 19.5 5.4 15.0 6.5 3.8 52.6 8.0 26.3 1.4 7.0 62.8 16.3 4.8 1.4 0.7 14.8 32.7 9.7 24.8 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 732.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 159.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 19.9 16.7 71.6 31.5 161.3 73.1 15.8 112.3 109.2 46.7 20.4 23.3 10.6 23.5 8.4 11.3 17.5 15.5 17.8 84.1 115.0 18.2 11.6 20.6 43.0 158.2 131.3 18.3 15.7 21.2 13.4 29.7 154.1 12.8 10.5 35.6 14.8 11.7 18.8 14.3 19.3 18.7 82.1 25.2 16.3 12.4 119.0 13.7 63.1 14.3 44.9 19.5 30.2 320.5 13.7 6.9 6.8 12.0 79.7 70.0 17.8 22.6 42.5 19.7 27.3 4.0 3.1 74.7 5.1 33.6 28.4 4.2 18.7 13.2 21.8 18.5 12.5 13.1 11.3 5.8 87.5 112.8 22.5 57.4 31.6 24.6 42.0 72.5 17.8 49.1 15.7 26.1 35.7 5.3 26.2 122.2 7.8 4.1 19.7 40.7 9.4 13.4 12.6 8.0 6.0 4.0 14.2 11.0 19.0 10.7 34.8 122.9 17.9 24.9 11.0 48.5 23.9 19.4 21.6 73.7 36.2 159.3 10.7 39.5 44.6 69.1 23.8 37.2 20.7 62.6 17.1 20.3 41.8 69.6 15.3 17.5 73.5 21.6 57.1 32.1 21.1 32.0 71.6 161.3 112.3 109.2 84.1 115.0 158.2 131.3 154.1 82.1 119.0 320.5 20.1 9.6 6.3 28.4 59.8 14.1 5.8 5.6 7.4 31.0 5.9 7.1 13.1 7.2 6.0 23.9 20.9 19.7 31.7 8.3 33.2 7.1 69.7 9.1 33.0 14.2 7.8 19.3 33.8 5.7 6.8 41.5 6.1 16.0 19.7 15.2 16.4 7.5 13.6 20.2 53.7 5.0 2.0 24.5 31.1 38.3 30.7 25.2 17.8 30.0 28.6 32.7 30.9 79.4 732.6 3.0 5.5 25.2 17.6 6.0 8.7 12.2 6.4 22.2 19.7 18.7 18.2 16.8 21.9 10.1 13.1 35.2 16.9 18.3 5.0 3.9 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 PYCR1 P5C ENSG00000183010 "Pyrroline-5-carboxylate reductase 1" P32322 17 81932384-81942412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis, Stress response" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 111.8;salivary gland: 121.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.8;Extravillous trophoblasts: 63.8;Intestinal goblet cells: 83.4;Prostatic glandular cells: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 4.2" "Group enriched" "Detected in many" 8 "B-cells: 4.2;dendritic cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047660 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 30: Mammary glandular cells - Lactation" "HPA047660: AB_2680115" "unprognostic (1.12e-2)" "unprognostic (2.13e-2)" "unprognostic (7.04e-2)" "unprognostic (7.27e-2)" "unprognostic (9.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (2.80e-1)" "unprognostic (9.36e-3)" "unprognostic (6.65e-2)" "unprognostic (3.02e-3)" "unprognostic (7.12e-2)" "prognostic unfavorable (7.33e-12)" "unprognostic (7.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.12e-2)" "unprognostic (5.92e-2)" 7.5 4.1 13.8 13.8 14.1 12.5 17.4 13.2 15.2 24.2 9.6 23.8 14.3 10.6 2.5 18.7 9.7 8.9 10.0 12.5 14.4 6.3 8.7 13.6 6.9 16.1 13.9 7.5 111.8 1.9 21.6 11.7 14.8 25.5 14.4 0.9 121.1 7.8 11.5 6.3 12.5 12.2 12.7 8.0 42.4 15.1 15.8 2.6 8.5 2.0 6.7 12.0 10.3 14.2 107.4 111.9 62.7 228.3 36.7 69.0 117.2 176.0 85.4 54.7 73.7 129.3 116.9 163.2 38.0 188.9 33.3 45.8 148.2 67.1 32.7 42.4 18.6 96.5 56.5 350.8 213.8 64.8 70.6 58.5 129.8 68.2 178.7 64.8 95.5 129.4 314.0 147.2 35.1 376.4 68.1 49.5 52.8 291.9 170.1 0.9 105.6 205.5 49.9 38.7 237.7 167.2 36.9 203.6 219.5 46.3 210.0 117.1 70.1 53.7 201.8 91.4 66.3 183.4 141.3 156.2 57.2 0.8 178.1 0.0 0.1 0.0 0.2 0.2 0.4 4.2 0.7 0.2 1.3 1.8 1.6 1.2 0.0 0.3 0.0 1.9 0.3 1.1 13.8 14.1 13.2 15.2 12.5 14.4 16.1 13.9 14.8 12.7 15.8 14.2 2.3 0.0 3.9 2.3 9.1 7.0 11.4 12.2 4.6 0.3 50.6 29.5 0.6 1.5 7.2 3.7 0.0 2.0 2.3 17.2 0.0 13.3 13.8 3.4 14.6 4.7 10.8 27.8 0.9 63.8 63.8 24.9 35.7 13.8 4.5 13.9 2.5 1.8 5.0 3.3 1.4 83.4 8.2 0.0 5.4 32.4 7.5 0.8 8.8 0.0 0.7 0.5 0.0 3.5 0.7 48.0 19.5 3.8 34.1 59.6 1.2 1.9 1.3 0.2 0.0 3.3 17.8 28.2 16.9 8.0 6.0 3.8 1.9 15.5 43.1 8.6 PYGM GSD5 ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64759974 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 65 "skeletal muscle: 8468.3;tongue: 3594.2" "Cell type enhanced" "Detected in many" "Astrocytes: 29.7;Cardiomyocytes: 47.5;Late spermatids: 49.2;Peritubular cells: 44.0;Skeletal myocytes: 64.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 8.1" "Cell line enhanced" "Detected in some" "HSkMC: 3.7;NB-4: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced NA NA 10000000 "Cluster 10: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA056003: AB_2683006" "unprognostic (3.33e-1)" "unprognostic (6.03e-3)" "unprognostic (3.87e-4)" "unprognostic (1.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (2.92e-1)" "unprognostic (3.88e-1)" "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (6.33e-6)" "unprognostic (3.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-2)" "unprognostic (5.68e-2)" 15.2 3.0 35.4 2.1 30.1 1.2 7.7 55.5 29.4 5.8 15.5 25.5 1.5 10.4 6.4 92.2 14.6 3.8 70.8 26.8 26.1 2.4 1.2 2.7 2.2 48.8 30.4 4.0 1.6 0.3 1.7 1.4 39.6 25.6 3.6 2.9 50.0 26.3 8468.3 4.2 7.0 14.7 44.9 3.3 6.9 6.7 47.3 1.3 5.2 3594.2 1.2 16.7 5.2 38.1 0.1 0.0 0.7 0.1 0.5 0.7 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 0.2 0.0 0.3 0.4 0.1 3.7 0.2 0.2 0.1 0.0 0.0 1.1 0.7 0.6 0.0 1.1 0.7 2.2 0.7 0.1 0.1 0.4 0.7 0.1 0.0 0.1 0.2 0.0 0.2 0.3 0.4 0.4 0.3 0.4 0.3 0.0 0.4 0.1 0.0 1.0 1.4 0.4 0.0 0.1 0.0 8.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 1.1 0.0 0.1 0.1 1.3 0.0 0.2 0.2 0.1 35.4 30.1 55.5 29.4 26.8 26.1 48.8 30.4 39.6 44.9 47.3 38.1 2.4 0.0 2.3 29.7 3.0 0.8 0.6 0.2 5.2 3.5 2.9 4.7 47.5 0.0 0.8 0.0 4.2 0.6 1.9 1.0 0.0 0.1 11.7 1.6 5.2 2.0 0.0 0.0 0.2 0.0 0.2 5.1 1.1 4.0 0.0 0.8 1.8 0.0 0.5 0.0 0.2 0.9 0.0 0.6 1.3 49.2 16.4 2.3 0.0 1.0 0.5 9.9 4.1 0.5 0.4 0.3 0.2 44.0 0.3 1.3 0.6 0.0 0.1 1.3 6.6 64.3 12.8 1.2 0.9 2.5 0.6 0.1 2.9 0.9 1.1 0.3 PYHIN1 "IFIX, MGC23885" ENSG00000163564 "Pyrin and HIN domain family member 1" Q6K0P9 1 158930796-158977059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 23.1" "Group enriched" "Detected in many" 5 "dendritic cells: 165.9;NK-cells: 324.4;T-cells: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "gdT-cell: 97.3;MAIT T-cell: 56.3;memory CD4 T-cell: 40.8;memory CD8 T-cell: 74.7;naive CD8 T-cell: 45.1;NK-cell: 36.8;T-reg: 67.3" "Group enriched" "Detected in many" 5 "NK-cells: 36.8;T-cells: 97.3" "Cell line enriched" "Detected in some" 6 "U-698: 49.1" "HPA051224, HPA055373" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli Nucleoplasm "HPA051224: AB_2681394, HPA055373: " "unprognostic (1.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.93e-3)" "unprognostic (2.64e-3)" "unprognostic (3.99e-2)" "unprognostic (3.57e-3)" "unprognostic (2.44e-3)" "unprognostic (2.10e-2)" "unprognostic (1.52e-1)" "unprognostic (1.47e-3)" "unprognostic (3.94e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-6)" "unprognostic (1.83e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-2)" "unprognostic (4.45e-3)" 2.3 0.6 0.2 8.3 0.3 5.5 1.2 0.2 0.4 1.0 0.4 1.7 1.6 1.1 0.8 0.8 0.9 3.8 0.6 0.3 0.4 0.7 3.2 3.7 23.1 0.7 0.3 0.8 0.3 0.2 0.3 0.9 0.6 1.0 2.1 0.1 1.6 0.5 0.3 0.5 5.4 0.7 0.2 13.9 2.7 0.4 0.5 3.7 1.4 0.6 12.5 3.3 0.8 1.2 0.0 0.0 0.0 0.0 0.7 0.4 0.6 0.0 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.1 0.1 0.0 0.0 0.9 0.0 49.1 0.0 7.7 0.0 1.5 0.3 0.4 97.3 0.4 56.3 14.8 40.8 74.7 0.3 8.7 13.5 45.1 3.5 36.8 0.5 0.6 67.3 21.0 0.2 0.3 0.2 0.4 0.3 0.4 0.7 0.3 0.6 0.2 0.5 1.2 1.3 12.8 2.8 1.0 17.0 0.4 0.6 0.0 0.0 0.5 1.2 0.9 0.6 0.0 2.0 3.7 0.0 0.1 165.9 0.1 0.0 0.1 0.3 0.5 0.3 1.2 0.0 7.4 0.5 0.0 0.0 2.7 2.6 0.2 2.5 0.1 3.9 1.2 2.7 0.0 0.5 0.0 0.0 5.0 1.5 0.3 0.0 3.5 1.8 6.5 2.3 0.5 324.4 0.0 0.2 0.0 0.0 0.0 37.9 0.6 0.0 0.6 5.3 1.1 0.0 0.7 0.7 0.1 0.2 0.1 0.6 0.1 104.7 0.0 0.2 0.4 QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 55.5;Cytotrophoblasts: 193.9;Extravillous trophoblasts: 156.7;Hofbauer cells: 96.1;Syncytiotrophoblasts: 187.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 58000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 61.1 58.8 20.0 57.2 21.3 96.6 89.5 23.5 18.5 58.3 34.2 104.8 101.6 45.5 58.5 102.5 71.0 48.3 72.0 18.4 21.1 57.1 51.1 52.3 75.8 23.8 21.0 69.0 73.9 78.1 33.0 76.7 23.0 60.4 121.0 21.4 103.2 61.1 156.1 105.0 84.6 60.2 22.7 60.1 75.0 30.0 23.0 92.3 53.2 146.2 118.8 72.8 58.1 24.6 95.9 97.8 128.0 197.4 146.4 180.8 159.2 90.5 188.2 160.5 152.9 123.0 113.5 257.1 61.4 136.7 95.3 119.9 166.3 137.8 111.4 78.2 148.0 206.4 156.0 216.1 91.2 187.2 130.9 184.8 123.1 127.4 108.1 175.3 184.7 144.6 95.3 112.4 118.0 89.2 130.7 154.9 116.1 159.0 122.9 76.0 123.7 200.6 108.5 163.9 48.7 161.6 85.4 211.0 147.8 122.7 184.4 205.5 137.6 82.8 127.3 131.7 117.9 111.9 176.5 142.9 88.4 156.3 60.3 30.7 84.3 25.8 44.5 104.1 57.4 62.2 54.1 47.0 127.0 49.9 46.6 49.0 8.0 71.8 94.5 57.4 82.1 81.2 20.0 21.3 23.5 18.5 18.4 21.1 23.8 21.0 23.0 22.7 23.0 24.6 15.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 193.9 11.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 156.7 14.7 0.0 0.0 0.0 0.0 0.0 0.0 96.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 187.0 2.0 0.0 0.0 0.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB15 ENSG00000139998 "RAB15, member RAS oncogene family" P59190 14 64945814-64973226 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.3;Inhibitory neurons: 28.0;Intestinal goblet cells: 35.2" "Cancer enhanced" "Detected in all" "testis cancer: 83.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "HAP1: 128.1;RH-30: 151.2;RT4: 116.1;SK-BR-3: 116.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041177 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Centriolar satellite" "HPA041177: AB_10794547" "unprognostic (9.80e-2)" "unprognostic (1.42e-2)" "unprognostic (1.53e-1)" "unprognostic (4.94e-2)" "unprognostic (6.29e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (7.14e-2)" "unprognostic (3.12e-1)" "unprognostic (4.25e-2)" "unprognostic (2.79e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-2)" "unprognostic (2.82e-2)" 2.8 4.9 30.0 6.2 35.0 0.8 8.4 28.2 43.2 7.3 13.4 13.5 12.7 4.2 5.6 4.3 4.7 6.2 33.4 38.9 22.6 19.3 21.2 9.9 3.8 21.2 20.7 2.2 12.6 39.4 9.6 16.1 28.6 10.9 20.2 5.8 36.5 4.6 10.0 7.2 13.1 11.8 17.2 2.8 10.9 1.7 25.5 7.7 6.7 1.2 3.0 17.9 5.0 31.5 10.9 57.0 20.3 20.3 4.5 6.4 57.6 6.7 9.3 13.5 11.8 26.8 28.4 0.6 3.9 16.5 6.2 10.9 128.1 1.3 9.5 3.6 6.2 12.3 1.1 23.5 0.6 0.6 7.5 4.4 2.5 5.9 1.2 3.5 42.6 29.2 0.4 2.0 23.9 61.8 15.2 11.3 45.8 65.6 8.2 18.5 151.2 1.0 15.8 116.1 65.4 12.7 3.4 116.7 15.0 23.6 33.2 11.8 11.2 11.5 49.0 5.5 8.7 0.6 0.4 5.8 2.4 0.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.9 0.1 0.0 30.0 35.0 28.2 43.2 38.9 22.6 21.2 20.7 28.6 17.2 25.5 31.5 1.7 6.4 3.9 5.9 0.8 2.5 3.2 1.3 0.6 2.9 12.4 7.4 22.2 4.3 4.2 16.5 0.0 24.7 5.0 5.5 3.9 7.9 0.5 6.6 2.8 3.7 1.2 0.0 51.3 12.2 16.0 2.0 2.6 13.6 1.3 4.1 4.6 8.7 2.7 11.8 28.0 35.2 0.0 0.3 1.3 1.1 0.3 0.9 0.0 4.7 1.0 2.0 1.0 10.6 4.9 13.0 5.5 1.5 0.2 5.6 2.9 5.9 1.3 2.9 0.0 2.4 5.2 0.9 0.4 1.6 1.1 17.9 1.5 1.5 12.0 14.1 RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 22.3;Peritubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC TERT1: 97.2;U-2197: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA029135: AB_10602070, HPA029136: AB_10601794" "unprognostic (8.78e-2)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.55e-2)" "unprognostic (5.33e-3)" "unprognostic (6.41e-2)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "unprognostic (9.12e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-3)" 9.6 6.1 8.6 13.2 9.0 0.8 7.8 10.9 9.6 45.9 6.1 59.7 7.0 52.6 14.1 19.9 14.5 26.9 12.3 8.5 15.2 7.3 4.1 10.6 4.5 8.7 8.7 10.8 2.9 5.7 3.4 27.6 9.5 38.7 15.9 3.9 3.9 55.7 6.1 4.8 10.8 75.0 9.2 2.2 11.6 5.1 9.7 3.2 32.6 10.4 4.1 46.7 14.7 11.5 15.6 6.1 21.6 15.3 32.3 97.2 19.8 44.9 77.4 38.6 39.7 13.4 7.3 3.1 13.6 72.3 19.3 5.5 22.7 16.4 45.6 11.6 10.5 11.3 9.4 10.6 19.8 5.9 1.6 36.5 18.6 48.1 44.7 18.7 20.3 6.6 17.6 9.3 43.4 13.2 5.2 6.3 8.1 10.3 8.2 5.7 31.7 4.7 26.8 10.7 11.2 7.6 22.5 10.6 11.6 26.8 9.7 6.8 27.4 59.6 18.5 177.4 26.6 8.0 9.3 7.6 33.5 12.5 30.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.0 8.6 9.0 10.9 9.6 8.5 15.2 8.7 8.7 9.5 9.2 9.7 11.5 2.9 12.8 5.0 6.8 0.7 4.1 1.6 2.0 5.7 2.5 4.0 3.0 3.4 1.5 1.6 0.0 2.1 11.5 1.7 2.4 0.0 3.4 2.4 6.5 15.5 2.6 1.2 4.8 13.0 2.9 10.7 22.3 1.1 6.2 0.0 3.7 4.6 3.4 4.2 1.7 12.3 1.4 2.0 0.8 3.1 2.5 19.9 1.4 5.4 11.2 7.7 4.4 0.0 8.0 5.3 2.6 0.1 30.5 0.5 3.5 0.6 6.1 5.3 0.9 0.0 17.2 14.5 6.6 7.8 4.1 5.1 13.7 0.8 4.0 1.6 1.8 RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 44.1" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Gastric mucus-secreting cells: 178.4;granulocytes: 246.6;Late spermatids: 209.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 63.3;hTCEpi: 46.6;hTERT-HME1: 56.0;U-87 MG: 165.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: AB_1856000" "unprognostic (1.59e-1)" "unprognostic (5.20e-2)" "unprognostic (9.89e-3)" "unprognostic (7.51e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-3)" "unprognostic (6.82e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.39e-2)" "unprognostic (1.20e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (5.75e-1)" "unprognostic (1.29e-1)" 0.3 2.6 7.9 1.1 10.2 1.0 11.9 0.0 11.9 3.0 0.0 4.9 5.1 0.8 0.4 14.0 1.1 3.8 0.1 13.3 5.2 0.3 1.3 7.2 0.5 0.0 0.1 0.2 4.1 2.3 1.0 1.1 0.6 20.5 5.3 1.0 14.0 1.0 0.2 15.6 4.9 0.9 0.1 1.7 44.1 4.5 2.6 1.4 0.3 0.5 5.2 6.2 5.2 3.3 7.8 22.4 0.8 0.0 1.5 19.3 0.0 1.7 13.5 1.8 1.3 0.0 8.6 1.3 0.1 3.9 16.7 14.5 0.2 9.0 0.5 0.0 0.5 63.3 5.0 0.0 2.6 3.4 7.0 15.3 46.6 25.5 56.0 21.1 1.2 0.3 0.0 3.9 16.1 7.9 0.2 7.4 0.2 14.0 14.7 0.0 0.0 0.3 4.1 28.9 0.2 10.3 2.2 13.4 0.0 0.1 8.3 0.3 0.3 18.8 0.6 9.8 2.0 0.4 0.0 0.0 165.2 35.6 0.9 0.6 0.0 0.1 2.2 0.0 0.5 0.0 0.7 1.1 0.0 0.0 0.2 1.0 0.2 2.6 0.0 0.0 0.0 1.6 7.9 10.2 0.0 11.9 13.3 5.2 0.0 0.1 0.6 0.1 2.6 3.3 0.3 48.1 37.6 3.3 0.9 25.6 8.6 18.2 8.0 2.4 59.8 25.3 0.5 8.6 36.9 5.5 2.1 6.5 15.0 5.7 1.9 7.2 259.3 30.9 4.4 1.9 4.2 3.4 101.0 41.0 4.5 2.0 178.4 64.0 246.6 0.4 2.5 0.9 0.6 6.7 75.8 31.3 20.3 0.6 2.7 209.9 2.1 38.1 7.2 2.8 2.1 1.4 29.9 98.5 2.6 34.0 18.6 0.4 3.2 78.9 3.0 0.0 15.8 0.4 6.6 0.3 2.2 7.9 1.4 79.2 49.2 2.9 13.9 0.5 7.9 42.2 RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.6;skin 1: 44.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.4;Basal respiratory cells: 74.8;Cytotrophoblasts: 94.5;Melanocytes: 131.6;Suprabasal keratinocytes: 98.5;Syncytiotrophoblasts: 54.7" "Cancer enhanced" "Detected in all" "melanoma: 73.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 87.7;hTCEpi: 308.0;hTERT-HME1: 271.4;SK-MEL-30: 175.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.1" HPA071701 Uncertain "Nuclear bodies,Mitochondria" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies, Mitochondria" "HPA071701: " "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (2.66e-2)" "unprognostic (1.36e-2)" "unprognostic (7.95e-2)" "unprognostic (3.96e-4)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "unprognostic (9.34e-2)" "unprognostic (1.00e-2)" "unprognostic (8.23e-2)" "prognostic favorable (8.26e-4)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" 2.6 27.8 0.4 1.4 0.4 1.6 8.6 0.3 0.8 11.8 6.3 1.9 2.4 4.7 6.7 48.6 5.6 6.0 1.1 0.7 0.6 4.5 1.8 5.8 1.7 0.5 0.7 3.3 1.6 1.8 2.8 14.7 0.5 2.4 1.3 2.9 7.7 6.4 0.6 44.3 2.3 3.6 0.4 1.6 1.6 2.5 0.8 3.5 7.9 0.4 17.9 8.7 23.5 0.6 10.7 1.4 0.3 0.5 0.4 2.4 0.6 6.5 26.1 10.4 19.0 4.7 4.8 0.5 6.3 6.9 1.2 71.2 5.7 87.7 14.1 1.3 5.1 54.0 6.2 0.0 1.0 0.6 0.6 2.2 308.0 1.4 271.4 13.0 12.3 1.0 0.3 0.9 0.0 0.0 0.7 18.4 8.2 0.7 0.1 0.5 0.1 0.8 20.0 40.6 1.9 1.2 0.3 0.1 175.6 6.2 15.7 4.6 6.7 0.0 4.6 0.0 1.1 1.5 6.5 0.2 1.7 2.2 1.2 0.0 0.8 0.1 1.5 0.6 0.8 0.0 0.4 1.8 1.6 0.0 0.1 0.8 0.6 18.0 1.3 4.4 1.0 0.7 0.4 0.4 0.3 0.8 0.7 0.6 0.5 0.7 0.5 0.4 0.8 0.6 1.0 0.0 6.7 0.7 0.1 46.4 15.9 74.8 21.1 0.1 6.9 9.7 0.2 8.6 25.0 0.0 0.0 94.5 2.7 0.5 3.9 1.7 0.0 2.1 0.9 2.7 0.0 5.5 0.6 1.1 10.5 9.1 3.1 2.3 16.5 5.3 1.1 0.0 17.5 0.0 0.4 0.3 14.2 1.6 21.2 0.1 3.4 3.9 131.6 3.7 6.3 0.6 1.0 2.0 0.1 2.6 2.6 1.2 0.1 9.5 2.1 5.3 7.4 6.4 0.0 0.6 5.3 0.1 5.9 38.1 98.5 54.7 2.7 5.9 2.5 23.3 RAB3B ENSG00000169213 "RAB3B, member RAS oncogene family" P20337 1 51907956-51990700 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 31.0;pituitary gland: 10.6;prostate: 11.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Alveolar cells type 2: 103.2;Enteroendocrine cells: 293.8;Pancreatic endocrine cells: 92.8" "Group enriched" "Detected in many" 6 "prostate cancer: 19.4;testis cancer: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 48.4;fHDF/TERT166: 45.8;TIME: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003159, CAB023293" Enhanced Approved "Cell Junctions" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Cell Junctions" "CAB023293: , HPA003159: AB_1856005" "unprognostic (1.10e-1)" "unprognostic (2.20e-3)" "unprognostic (5.43e-3)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (1.38e-2)" "unprognostic (1.20e-2)" "unprognostic (8.77e-3)" "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-2)" "unprognostic (2.02e-3)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" 0.0 3.0 11.3 0.6 8.6 0.2 0.7 2.9 14.9 0.0 0.0 1.6 0.7 0.1 0.2 0.0 0.2 1.3 0.0 10.9 23.0 0.5 0.7 0.0 0.1 11.4 17.5 1.5 1.0 0.0 10.6 1.6 31.0 11.0 2.3 1.7 0.2 0.1 0.5 1.9 0.9 0.3 2.3 0.1 1.2 0.3 19.5 0.2 0.0 0.0 0.1 0.1 0.1 3.4 1.8 8.5 1.2 1.3 0.2 2.3 0.2 125.8 48.4 24.8 12.0 10.4 3.7 0.6 2.0 45.8 3.6 0.1 15.4 13.0 41.7 0.0 1.1 0.1 0.6 3.4 2.1 0.0 0.1 1.1 0.4 41.1 9.4 15.4 7.8 1.1 0.4 0.4 27.9 0.3 0.1 0.1 19.9 2.4 1.2 0.3 0.2 0.2 4.0 0.8 4.3 1.1 0.1 0.3 0.1 24.6 0.2 0.3 97.9 24.0 8.8 0.5 41.5 0.2 0.6 0.4 21.9 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 11.3 8.6 2.9 14.9 10.9 23.0 11.4 17.5 31.0 2.3 19.5 3.4 1.4 147.4 103.2 0.3 1.1 2.4 6.2 0.3 0.0 5.0 2.2 3.4 0.7 12.8 27.9 0.0 2.1 0.5 0.4 2.0 3.9 4.0 2.4 1.5 1.3 8.2 293.8 0.0 6.6 18.4 0.3 13.9 3.6 1.4 7.6 27.9 0.7 2.7 0.3 0.0 48.1 14.7 14.2 1.3 1.2 1.3 0.6 3.7 1.8 1.0 1.0 31.2 1.0 1.5 1.5 92.8 1.4 1.2 2.3 18.8 1.4 0.2 29.5 3.7 0.0 4.1 4.8 10.4 4.3 0.0 1.4 4.0 3.3 1.1 1.6 2.7 RAB3D "D2-2, GOV, RAB16, RAD3D" ENSG00000105514 "RAB3D, member RAS oncogene family" O95716 19 11322068-11346270 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.5;skin 1: 53.1" "Cell type enhanced" "Detected in many" "monocytes: 53.1;Squamous epithelial cells: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 47.3;Karpas-707: 45.6;MCF7: 54.6;SK-BR-3: 68.8" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 73.1" "CAB018067, HPA063283" Approved Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB018067: AB_606903, HPA063283: AB_2684976" "unprognostic (4.71e-3)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (4.17e-3)" "unprognostic (7.27e-3)" "unprognostic (1.55e-1)" "unprognostic (2.80e-1)" "unprognostic (8.76e-2)" "unprognostic (9.92e-2)" "unprognostic (4.45e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (9.15e-2)" "unprognostic (1.34e-1)" 5.5 3.4 11.5 5.1 9.9 17.6 12.2 8.5 13.0 15.0 6.3 8.1 8.1 7.3 6.1 34.1 8.7 3.9 3.6 16.1 13.0 5.8 1.8 8.7 2.4 20.7 10.8 4.2 68.5 4.4 4.7 7.2 23.4 17.1 8.6 1.7 30.1 8.1 2.5 53.1 6.1 8.8 12.2 8.8 19.5 1.4 15.2 4.7 6.2 4.2 9.1 7.0 15.2 14.1 1.5 14.2 4.4 17.7 7.1 12.3 0.9 1.3 3.8 2.5 2.5 5.1 0.5 0.6 16.0 8.6 4.7 19.1 7.5 11.9 2.2 7.8 1.1 5.8 6.7 5.8 4.4 3.1 13.2 5.3 47.3 2.1 5.1 6.5 20.5 4.3 2.1 45.6 0.8 54.6 2.2 6.9 3.7 28.7 14.4 2.1 0.0 16.1 22.0 14.2 4.9 9.5 4.3 68.8 9.3 6.0 41.1 35.1 7.9 2.4 0.8 11.4 0.2 15.5 21.3 3.2 8.4 19.0 2.6 123.5 84.1 95.6 3.2 51.4 5.6 2.2 3.2 2.6 35.5 2.2 2.2 2.7 169.1 1.6 41.3 0.9 5.7 26.3 11.5 9.9 8.5 13.0 16.1 13.0 20.7 10.8 23.4 12.2 15.2 14.1 10.0 6.4 17.2 4.6 4.0 15.7 4.5 13.7 12.5 0.7 23.6 14.1 4.3 10.0 19.1 14.7 0.0 8.0 4.4 5.7 11.7 4.8 0.5 5.4 6.6 9.7 18.6 5.9 9.2 25.6 6.6 5.4 23.0 14.0 12.7 4.1 17.9 1.5 9.4 0.0 5.4 29.3 4.1 40.0 2.4 0.2 4.4 16.0 8.8 5.6 53.1 5.3 2.1 1.0 1.3 12.7 5.8 4.9 8.5 11.7 1.4 3.6 1.8 0.4 6.6 3.3 8.5 0.1 2.5 47.8 37.8 10.4 3.9 3.8 15.4 5.9 RAB3IP "FLJ22548, RABIN3, RABIN8" ENSG00000127328 "RAB3A interacting protein" Q96QF0 12 69738860-69823204 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 210.4;Early spermatids: 287.3;Late spermatids: 453.9;Oligodendrocyte precursor cells: 261.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039794 Uncertain Approved "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA039794: AB_10960557" "unprognostic (4.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.66e-2)" "unprognostic (8.57e-2)" "unprognostic (3.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (7.10e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.16e-2)" "unprognostic (1.24e-1)" "prognostic favorable (5.68e-13)" "unprognostic (6.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (3.37e-1)" 3.7 15.9 17.7 6.4 22.0 25.6 19.9 79.7 16.9 8.4 51.6 21.7 19.2 5.5 44.3 8.6 15.2 15.1 18.3 18.7 18.9 48.5 16.6 14.9 13.6 25.7 21.7 3.1 22.8 26.9 20.2 12.0 26.2 20.8 22.6 88.6 12.8 9.7 9.7 11.8 22.4 4.9 12.1 6.8 18.4 74.7 19.7 12.7 16.2 14.3 15.3 11.8 4.8 25.6 44.1 23.5 14.3 22.9 6.9 3.1 41.0 4.3 9.9 16.9 22.6 67.3 19.1 34.1 13.9 2.3 21.9 33.0 14.7 22.9 29.0 51.7 25.6 25.3 8.4 32.9 6.4 29.9 15.4 7.4 23.3 15.6 52.4 17.5 24.8 44.4 12.1 30.3 9.6 46.8 30.3 12.8 35.7 46.1 25.7 35.3 22.2 35.9 55.1 53.5 56.7 10.2 16.7 28.0 6.4 57.0 47.6 11.1 7.4 7.2 18.3 3.0 20.3 14.2 63.4 156.9 17.5 18.3 11.2 1.8 5.2 7.2 4.2 1.9 8.5 9.2 7.5 6.8 5.6 8.6 9.3 9.1 6.9 7.8 2.3 5.1 12.6 4.4 17.7 22.0 79.7 16.9 18.7 18.9 25.7 21.7 26.2 12.1 19.7 25.6 4.0 60.9 51.1 19.6 17.7 23.6 55.6 28.8 19.4 210.4 44.6 13.0 50.2 85.8 48.8 51.5 110.5 21.7 6.4 33.1 37.2 64.6 287.3 79.7 5.2 8.7 40.8 14.1 22.6 31.8 8.2 6.4 39.3 119.7 2.5 19.3 7.1 16.5 3.5 28.6 186.1 39.3 46.8 1.9 7.5 453.9 4.4 8.0 5.4 9.4 16.6 96.6 4.1 261.9 104.1 51.1 38.6 3.8 25.9 77.9 46.1 82.1 54.4 95.8 6.6 31.8 12.3 48.9 37.7 24.2 29.8 8.5 15.1 3.5 45.8 76.7 RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;breast: 2.5;parathyroid gland: 3.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 10.3;Oligodendrocytes: 3.3" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.5;HMC-1: 2.2;REH: 5.4;T-47d: 3.2;U-266/70: 2.1" HPA059131 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (8.62e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-1)" 0.1 0.6 1.4 0.1 2.2 0.0 2.5 0.7 1.9 1.9 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 1.3 1.6 0.1 0.0 0.0 0.0 1.2 1.2 0.1 0.0 3.6 0.2 0.3 1.3 1.7 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.7 0.5 0.0 0.9 1.6 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.1 0.5 3.2 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 0.7 1.9 1.3 1.6 1.2 1.2 1.3 0.7 1.6 3.6 0.1 0.0 0.0 0.3 0.1 0.8 0.3 0.3 0.0 0.0 0.9 0.1 10.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.1 1.7 1.0 0.0 0.0 0.7 0.0 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.3 0.4 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.0 0.6 0.7 0.0 0.1 0.0 0.0 0.6 1.4 1.4 1.3 0.0 1.1 0.5 0.1 0.1 0.1 0.3 RAB6D "RAB6CL, WTH3DI" ENSG00000233087 "RAB6D, member RAS oncogene family" Q53S08 2 131361111-131364142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 7.4" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Cancer enhanced" "Detected in some" "prostate cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 2.2" HPA059131 Uncertain Approved "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (4.19e-2)" "unprognostic (8.54e-2)" "unprognostic (1.16e-1)" "unprognostic (3.03e-2)" "unprognostic (4.08e-1)" "unprognostic (4.79e-2)" "unprognostic (4.41e-2)" "unprognostic (1.01e-1)" "unprognostic (1.87e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-1)" "unprognostic (2.55e-2)" "unprognostic (2.61e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.12e-1)" 0.0 0.2 0.6 0.1 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.9 0.2 0.1 0.3 0.0 0.1 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 7.4 0.0 0.0 0.5 1.4 0.8 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.2 0.0 0.0 1.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.3 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.8 0.6 0.9 0.3 0.2 0.5 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RAB9B RAB9L ENSG00000123570 "RAB9B, member RAS oncogene family" Q9NP90 X 103822327-103832257 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 21.3;Cardiomyocytes: 79.0;Excitatory neurons: 28.4;Inhibitory neurons: 18.7;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 37.7;Peritubular cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 4.5;MOLT-4: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061932 Approved "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061932: AB_2684640" "unprognostic (1.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (7.28e-5)" "unprognostic (5.81e-2)" "unprognostic (3.89e-2)" "unprognostic (8.40e-2)" "unprognostic (1.42e-2)" "unprognostic (8.34e-2)" "unprognostic (8.29e-2)" "unprognostic (3.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.21e-4)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" 1.8 2.8 6.4 0.9 6.6 0.1 1.3 8.1 7.2 3.0 0.0 6.5 1.0 5.0 2.4 8.3 6.8 2.4 21.5 6.2 8.8 0.4 0.1 0.7 0.6 4.0 3.6 7.2 1.0 3.9 5.1 0.2 6.8 7.1 2.2 5.2 1.1 9.5 9.4 0.5 1.7 9.8 3.7 0.5 2.2 1.8 8.8 1.5 1.4 5.6 0.4 7.0 1.6 4.7 0.0 0.0 2.9 1.5 0.8 0.1 0.1 0.7 1.8 1.8 1.7 0.2 0.0 0.1 1.7 1.5 1.1 0.0 0.5 0.1 1.6 0.1 1.9 0.1 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.8 0.0 1.8 0.1 4.5 0.0 1.1 0.1 1.3 3.7 0.0 0.5 0.0 0.5 3.2 3.3 0.1 1.0 0.3 3.0 2.1 0.2 0.1 0.6 0.5 0.3 0.2 0.1 0.1 0.5 1.0 0.6 0.1 0.0 0.2 1.6 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.8 0.0 0.1 0.1 0.0 6.4 6.6 8.1 7.2 6.2 8.8 4.0 3.6 6.8 3.7 8.8 4.7 1.0 0.0 2.4 8.5 0.7 0.4 0.7 0.1 0.6 21.3 1.6 1.9 79.0 0.0 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.5 0.0 0.3 0.7 2.4 7.7 1.3 28.4 1.0 0.3 4.1 0.0 0.2 4.5 2.8 0.7 0.0 0.3 0.0 18.7 0.7 0.0 0.0 0.4 0.9 6.5 0.2 0.0 1.9 0.0 32.2 2.1 37.7 6.2 1.0 2.5 30.1 0.1 0.2 0.1 0.2 0.8 3.6 6.6 2.3 5.0 0.8 0.9 0.5 0.3 0.0 0.2 4.7 0.6 0.2 RABEP2 "FLJ23282, FRA" ENSG00000177548 "Rabaptin, RAB GTPase binding effector protein 2" Q9H5N1 16 28904421-28936526 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047641 Approved Supported Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA047641: AB_2680111" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.84e-4)" "unprognostic (2.46e-1)" "unprognostic (1.42e-1)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (1.26e-3)" "unprognostic (5.86e-2)" "prognostic favorable (1.24e-6)" "unprognostic (7.50e-2)" "unprognostic (8.20e-2)" "unprognostic (1.08e-1)" "unprognostic (5.92e-3)" 7.3 21.5 7.3 25.1 8.8 11.5 9.3 8.2 9.2 11.0 10.7 15.0 16.8 8.4 2.7 18.7 7.0 6.6 16.8 6.5 7.9 19.2 10.6 10.1 46.7 10.7 8.5 6.3 17.9 11.5 16.4 5.3 8.4 28.6 4.6 3.5 17.5 7.0 6.5 23.6 28.3 3.4 7.9 47.9 14.4 6.2 8.2 5.3 13.9 3.2 9.4 12.5 12.3 8.5 13.5 21.1 5.6 10.5 3.3 4.7 10.1 15.5 9.2 10.9 10.7 15.9 12.0 27.7 23.7 6.5 4.4 17.8 2.2 9.9 2.1 9.5 9.9 10.5 17.0 21.7 6.5 7.7 32.1 7.9 8.0 13.5 2.4 6.3 15.5 7.4 4.9 9.7 8.5 31.9 9.5 17.8 7.3 5.4 11.4 33.6 5.1 17.4 7.5 17.5 8.6 11.1 7.6 34.8 7.0 1.2 27.6 15.9 27.5 16.4 8.4 12.1 15.6 15.3 5.0 20.7 17.3 18.2 12.6 0.9 2.8 2.4 3.5 2.9 2.4 12.1 2.5 3.2 3.7 15.0 2.2 2.1 0.7 5.5 3.3 2.2 2.2 2.8 7.3 8.8 8.2 9.2 6.5 7.9 10.7 8.5 8.4 7.9 8.2 8.5 11.5 3.2 10.0 4.9 42.4 5.1 14.7 14.6 17.6 11.1 13.3 11.0 1.9 11.5 12.9 20.2 35.5 26.1 21.0 35.0 17.6 16.0 0.7 9.2 8.2 14.2 17.3 6.5 4.8 20.9 7.1 9.0 23.0 10.0 18.4 12.1 7.9 4.2 12.4 15.2 6.5 33.7 18.3 8.4 11.3 1.3 4.1 10.5 10.6 9.4 11.6 8.6 22.6 5.0 8.4 20.0 44.1 6.4 21.4 15.4 32.3 11.6 8.0 43.4 13.1 7.9 9.6 4.3 6.0 16.6 8.4 22.0 14.5 22.6 26.7 19.0 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 RAC3 ENSG00000169750 "Rac family small GTPase 3" P60763 17 82031678-82034204 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 45.0;Extravillous trophoblasts: 152.1;Spermatogonia: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "CACO-2: 230.8;HEK 293: 274.7;NB-4: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047820 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA047820: AB_2680167" "unprognostic (3.48e-2)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (1.62e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (3.36e-2)" "unprognostic (1.57e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-2)" "unprognostic (3.67e-1)" "unprognostic (4.39e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.25e-3)" 12.3 5.0 22.8 1.8 20.8 7.7 13.7 26.3 29.5 5.3 9.3 4.8 3.4 2.8 7.3 10.9 3.8 3.0 3.0 19.7 24.5 9.4 20.7 4.0 1.7 23.3 22.3 4.8 4.7 9.3 22.8 5.6 27.0 11.1 1.4 2.8 18.1 4.2 0.8 12.4 3.7 1.3 15.3 1.9 11.8 28.1 26.5 2.2 9.8 0.2 1.5 3.1 7.6 20.6 11.1 15.1 45.6 63.1 9.7 18.2 50.5 7.8 7.2 26.1 22.3 230.8 21.4 5.8 11.5 4.8 1.7 15.6 43.0 17.8 4.1 3.6 274.7 64.6 20.2 16.7 47.0 28.0 12.2 27.5 13.0 3.5 12.0 19.5 60.3 33.8 103.1 30.2 10.8 35.6 7.3 156.4 61.4 39.2 27.6 47.6 4.5 27.7 20.0 5.4 109.8 111.5 4.1 57.2 55.7 16.1 58.6 40.7 21.6 10.8 9.8 5.5 12.1 14.6 9.9 4.4 6.6 17.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 22.8 20.8 26.3 29.5 19.7 24.5 23.3 22.3 27.0 15.3 26.5 20.6 1.6 0.0 0.0 2.3 0.9 8.7 16.3 12.2 19.9 5.3 36.9 45.0 0.2 4.3 3.6 5.5 0.0 30.0 1.8 3.3 21.5 9.8 19.1 5.9 5.4 2.3 3.0 6.9 5.2 3.3 152.1 10.7 8.2 12.6 4.5 17.8 1.4 11.3 9.7 6.7 8.3 5.1 22.4 0.0 2.6 16.6 5.6 0.9 14.2 0.0 2.0 6.0 0.0 3.5 2.0 5.5 2.4 1.9 2.6 16.4 4.2 26.0 2.4 7.3 0.0 0.8 5.3 2.2 58.0 15.8 7.5 14.1 3.1 8.6 5.2 8.4 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RALGDS "RalGEF, RGDS, RGF" ENSG00000160271 "Ral guanine nucleotide dissociation stimulator" Q12967 9 133097720-133149334 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 24.0;MAIT T-cell: 9.7;memory CD4 T-cell: 10.9;memory CD8 T-cell: 17.6;naive CD8 T-cell: 9.1;NK-cell: 9.0;T-reg: 20.8" "Group enriched" "Detected in many" 7 "NK-cells: 9.0;T-cells: 24.0" "Cell line enhanced" "Detected in all" "HDLM-2: 152.4;SH-SY5Y: 92.0" "HPA025961, CAB032582" Approved Uncertain Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB032582: AB_2238105, HPA025961: AB_2671795" "unprognostic (1.01e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.35e-2)" "unprognostic (7.92e-3)" "unprognostic (8.20e-2)" "unprognostic (7.95e-2)" "unprognostic (5.09e-2)" "unprognostic (2.20e-1)" "unprognostic (8.91e-2)" "unprognostic (2.88e-1)" "unprognostic (2.69e-3)" "unprognostic (5.03e-2)" "unprognostic (9.54e-3)" "unprognostic (5.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" 36.8 29.7 68.3 20.2 88.1 41.8 35.5 76.3 75.8 22.2 34.7 28.2 17.3 19.0 12.8 40.5 23.9 31.3 26.8 66.8 66.5 14.8 13.4 35.7 27.6 91.3 87.5 33.0 22.9 16.6 68.5 10.9 84.4 25.0 10.1 7.3 31.8 20.3 32.5 62.3 25.2 13.6 73.5 22.2 21.4 6.1 86.1 15.8 23.5 16.3 16.9 38.8 29.6 117.9 7.5 10.9 22.2 27.8 8.3 12.1 18.7 8.8 13.0 8.8 5.7 9.5 16.1 11.3 8.0 15.1 13.4 33.8 22.7 16.1 2.9 152.4 16.3 9.6 22.0 13.8 10.8 15.6 16.9 14.2 22.1 4.7 9.7 23.7 18.2 21.7 19.3 68.4 8.3 24.6 22.2 15.0 15.3 33.3 27.6 22.2 5.4 18.9 10.8 13.0 70.1 92.0 10.5 15.4 14.0 8.6 16.0 15.9 9.5 9.8 10.3 7.4 6.1 3.2 9.2 14.0 8.6 17.4 11.2 2.3 0.6 0.9 24.0 0.3 9.7 1.7 10.9 17.6 0.8 0.5 2.4 9.1 0.4 9.0 0.3 0.8 20.8 6.1 68.3 88.1 76.3 75.8 66.8 66.5 91.3 87.5 84.4 73.5 86.1 117.9 83.9 32.1 11.3 43.4 17.2 55.4 46.3 19.5 40.5 16.6 55.5 40.5 7.2 12.8 21.4 9.2 12.5 5.5 45.7 40.6 3.9 11.4 0.6 100.2 11.7 54.1 37.0 14.3 34.1 6.7 4.5 21.8 26.0 93.1 15.8 26.9 36.4 3.8 12.5 62.2 29.8 14.4 22.4 9.8 51.1 1.8 13.4 33.6 23.2 12.2 4.9 16.3 46.4 32.2 86.4 11.5 31.5 9.1 26.5 43.9 26.7 2.5 34.5 9.3 0.0 43.7 15.4 2.5 5.1 47.6 101.4 5.9 41.6 19.6 17.6 116.6 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAP1A "KREV-1, SMGP21" ENSG00000116473 "RAP1A, member of RAS oncogene family" P62834 1 111542218-111716691 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" Neurogenesis Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 494.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.37e-3)" "unprognostic (7.49e-2)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.88e-2)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" "unprognostic (6.10e-2)" "unprognostic (4.98e-3)" "unprognostic (1.54e-2)" "unprognostic (1.84e-1)" "unprognostic (3.44e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (3.08e-1)" 91.6 59.9 45.4 101.8 55.6 81.4 57.5 55.4 71.1 52.2 41.6 160.2 67.8 53.8 82.2 107.5 51.6 63.3 93.9 42.9 52.1 70.8 98.1 77.3 114.0 57.7 53.3 41.3 36.0 123.4 32.9 65.5 59.5 67.9 94.4 26.9 66.3 96.4 89.4 38.7 75.1 89.5 56.3 89.5 78.9 17.9 49.9 76.7 65.2 86.6 123.6 100.8 45.4 67.9 162.8 25.1 61.1 36.1 121.7 116.7 56.5 105.7 112.2 75.0 84.4 83.3 65.9 132.0 72.5 133.1 48.2 57.6 56.5 79.4 138.9 494.7 58.7 96.0 61.4 51.9 124.0 101.4 95.7 76.0 90.9 83.5 86.8 69.7 100.3 73.9 73.8 142.3 104.6 74.4 52.7 128.0 36.2 72.1 66.5 56.9 129.4 65.9 120.2 80.9 43.3 30.8 129.9 75.6 99.3 61.9 38.3 127.9 94.5 60.2 77.2 76.2 104.4 151.2 54.7 145.4 83.9 152.7 161.1 15.6 22.1 21.1 17.0 23.6 20.0 16.4 29.0 25.9 26.2 10.6 21.5 20.9 48.4 22.1 21.6 13.0 29.0 19.0 45.4 55.6 55.4 71.1 42.9 52.1 57.7 53.3 59.5 56.3 49.9 67.9 107.5 67.3 83.1 36.2 104.8 123.9 103.5 65.2 31.9 17.4 49.3 33.1 122.6 41.5 60.0 46.0 4.2 70.5 117.8 134.2 158.5 73.4 28.1 27.6 39.9 118.4 40.8 149.7 73.1 69.8 76.1 78.4 56.6 38.8 85.6 24.8 97.1 60.3 209.2 50.5 78.1 130.8 46.8 245.4 265.5 14.4 63.3 193.6 101.4 182.7 179.7 71.4 148.3 62.4 203.4 74.9 88.3 78.2 119.2 125.1 104.7 133.8 40.4 11.7 118.3 80.5 141.5 26.0 10.9 42.1 101.7 82.1 168.3 89.6 84.0 152.7 RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.1;Distal tubular cells: 72.4;Excitatory neurons: 82.0;Horizontal cells: 92.5;Intestinal goblet cells: 112.6;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 46.3;OE19: 162.8;SCLC-21H: 52.1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" 0.6 80.8 74.0 2.6 118.6 0.8 4.4 24.6 91.9 7.5 0.0 19.7 12.4 1.9 1.9 7.5 4.2 24.9 9.5 76.2 34.5 152.4 36.1 14.2 1.0 35.8 22.0 1.6 106.2 57.1 37.9 2.1 32.8 12.8 17.3 27.3 88.7 0.8 0.2 3.5 21.7 0.7 15.8 1.2 110.8 3.6 32.4 0.5 162.8 0.3 0.9 4.0 3.4 67.3 6.2 46.3 0.5 3.6 0.0 0.0 0.8 0.0 0.1 0.1 0.0 4.3 6.4 0.1 4.6 0.2 30.2 7.9 4.4 0.3 0.1 1.0 2.3 2.2 4.3 22.1 0.7 0.0 6.6 0.3 3.1 0.0 0.0 0.0 0.0 22.1 29.6 1.1 0.0 15.6 7.7 0.7 2.8 162.8 7.0 4.3 1.2 1.1 10.2 3.4 52.1 9.3 7.7 27.4 8.9 1.8 2.7 5.2 0.1 0.0 3.1 0.0 0.1 0.6 0.1 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.0 118.6 24.6 91.9 76.2 34.5 35.8 22.0 32.8 15.8 32.4 67.3 0.0 9.6 29.3 10.4 0.5 1.3 1.1 1.1 0.6 64.1 8.5 5.6 5.1 25.8 4.5 14.7 0.0 0.2 0.1 4.3 72.4 25.1 0.8 3.1 0.6 0.4 6.7 4.0 82.0 28.8 1.4 1.0 17.3 8.0 0.0 6.2 0.4 8.5 0.3 92.5 45.8 112.6 6.1 0.6 0.3 0.3 0.0 0.6 16.0 3.7 0.6 11.5 0.0 51.8 18.6 15.3 17.2 0.0 0.2 5.0 6.0 13.5 1.2 7.3 0.0 0.0 0.7 1.0 3.6 0.5 1.1 1.5 0.3 2.5 7.7 2.6 RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.7;pancreas: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 132.8;Inhibitory neurons: 67.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 12 "amygdala: 10.6;basal ganglia: 13.6;cerebral cortex: 11.0;hippocampal formation: 17.9;white matter: 11.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022148, HPA022896" Approved Supported "Nuclear membrane,Cytosol" NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Cytosol" "HPA022148: AB_1849474, HPA022896: AB_1849476" "unprognostic (1.85e-3)" "unprognostic (1.02e-2)" "unprognostic (8.92e-2)" "unprognostic (5.39e-1)" "unprognostic (4.04e-2)" "unprognostic (3.92e-1)" "unprognostic (6.52e-5)" "unprognostic (1.18e-2)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.66e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.36e-6)" "unprognostic (3.44e-2)" "unprognostic (6.38e-2)" "unprognostic (9.33e-2)" "unprognostic (7.50e-2)" 1.8 6.4 10.6 4.1 13.6 27.7 4.4 0.9 11.0 3.9 0.0 7.9 8.7 4.1 1.1 3.1 8.1 4.0 14.5 17.9 1.1 5.2 0.6 3.5 2.9 0.0 0.0 4.6 37.3 4.2 5.1 4.9 0.0 3.8 8.1 7.2 10.9 4.7 0.8 3.3 8.2 3.3 0.0 3.9 22.4 3.2 0.0 2.8 2.5 2.0 2.5 2.0 2.5 11.9 8.1 9.9 1.9 8.1 0.0 0.0 15.9 10.7 5.0 1.3 1.2 21.9 3.5 3.0 2.9 1.4 13.5 11.0 6.4 20.0 0.4 0.0 6.9 3.7 14.1 9.9 1.9 0.8 3.9 0.5 17.0 5.5 13.9 7.2 0.2 3.7 21.4 1.4 0.0 9.1 3.1 2.0 11.7 3.9 9.5 13.4 6.9 7.8 5.9 4.1 21.6 52.3 15.5 15.8 6.9 7.4 7.8 2.3 2.4 9.1 14.3 1.6 9.1 0.0 0.0 1.2 0.5 6.9 15.1 0.9 1.4 2.1 2.8 2.7 1.1 0.2 0.9 2.1 1.0 0.2 0.1 1.0 4.2 1.9 3.9 1.7 1.0 1.4 10.6 13.6 0.9 11.0 17.9 1.1 0.0 0.0 0.0 0.0 0.0 11.9 1.5 6.4 2.5 13.7 5.6 2.0 6.6 1.8 1.2 23.6 9.9 7.6 20.2 11.5 2.8 12.9 33.3 7.5 27.2 15.2 9.8 6.0 6.1 9.2 6.8 1.6 48.1 0.8 132.8 12.0 6.0 2.2 18.8 9.2 6.3 3.0 3.6 0.8 3.4 37.0 67.9 21.7 8.2 11.1 4.3 8.3 1.8 11.0 3.6 47.8 12.0 2.1 35.0 8.0 4.2 12.4 24.1 1.5 6.4 16.5 5.7 0.8 4.2 4.6 0.0 7.9 2.5 0.4 3.4 2.8 0.4 3.4 8.2 1.5 14.0 11.3 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2400.4;liver: 1994.6;pancreas: 1482.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 659.2;Hepatocytes: 2819.0;Muller glia cells: 785.1" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Group enriched" "Detected in many" 6 "AF22: 132.9;Hep G2: 213.8;HHSteC: 172.9;NTERA-2: 411.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 75000000 460000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" 525.6 2400.4 61.0 87.4 62.1 0.4 295.6 56.2 70.2 522.4 321.7 386.8 53.2 359.2 55.9 78.7 408.5 116.5 212.7 62.0 63.3 271.9 1994.6 466.8 109.8 65.9 73.6 626.3 1482.0 627.1 104.1 59.0 63.3 262.5 78.3 33.9 56.2 114.7 18.3 60.4 185.9 103.0 64.8 149.5 180.0 26.9 64.5 9.8 85.0 34.6 63.1 265.3 380.7 66.7 0.0 0.1 132.9 0.3 0.0 0.0 2.1 11.9 25.2 4.2 17.2 1.2 8.2 1.1 15.0 2.9 1.3 0.5 0.0 0.0 0.0 2.4 0.5 0.6 23.6 213.8 172.9 2.2 0.4 36.4 0.0 0.0 0.0 2.8 0.0 0.4 0.4 0.4 4.2 0.9 2.1 2.4 411.9 1.2 0.0 0.1 17.1 0.4 2.8 1.1 0.6 1.2 2.3 0.1 0.4 1.9 0.6 0.0 0.0 0.4 1.8 0.8 0.6 1.4 0.9 1.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 5.4 0.0 0.0 61.0 62.1 56.2 70.2 62.0 63.3 65.9 73.6 63.3 64.8 64.5 66.7 47.1 67.3 32.0 9.4 7.0 35.1 80.7 16.8 15.9 7.0 26.2 39.0 75.0 381.8 45.0 82.8 2.1 10.1 1.9 172.6 103.7 19.8 3.7 39.9 128.7 27.1 97.4 32.0 0.4 659.2 4.3 469.6 8.2 16.4 12.0 207.5 84.6 2819.0 11.6 10.1 0.4 233.9 541.2 53.8 42.4 19.3 454.2 8.9 44.4 7.5 1.0 785.1 0.0 9.0 0.3 209.1 107.4 194.9 1.2 82.0 1.2 269.1 29.8 25.4 13.1 302.5 181.1 4.9 5.2 4.4 28.8 14.6 12.3 307.5 418.7 31.9 RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 59.8;salivary gland: 28.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 36.8;Excitatory neurons: 14.0;Gastric mucus-secreting cells: 57.1;Oligodendrocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 15.3;EFO-21: 19.3;REH: 22.3;RPMI-8226: 50.0;RPTEC TERT1: 19.0;U-698: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" 0.0 15.4 10.9 1.2 13.8 0.5 1.0 0.5 19.1 3.5 1.1 1.7 0.4 0.1 0.1 22.6 1.6 0.3 0.0 23.6 4.0 17.2 0.1 0.2 1.1 1.7 4.3 0.0 1.1 59.8 5.0 0.2 1.8 0.2 1.1 0.5 28.5 3.9 0.0 11.4 0.5 0.0 0.6 0.2 10.6 0.7 7.7 0.2 10.1 0.0 2.7 0.2 5.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 15.3 19.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 4.3 0.0 0.0 0.6 5.5 0.0 22.3 0.0 50.0 19.0 0.0 0.5 0.0 0.0 7.2 0.0 0.1 2.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 13.8 0.5 19.1 23.6 4.0 1.7 4.3 1.8 0.6 7.7 12.1 0.0 0.0 0.0 1.3 0.8 0.5 0.0 0.4 0.0 0.5 2.4 2.0 4.3 2.8 1.0 36.8 0.0 1.1 0.0 1.9 0.0 1.4 0.1 1.8 0.6 0.3 1.2 0.0 14.0 0.0 0.2 0.3 57.1 4.6 2.5 0.0 0.0 0.0 0.4 0.0 1.0 4.8 0.0 0.0 5.5 0.2 0.0 1.2 1.8 0.0 1.0 2.7 0.0 0.0 46.5 5.2 3.3 0.0 0.6 0.0 0.1 5.2 0.5 0.0 0.0 0.0 0.2 0.1 0.7 4.6 1.1 1.2 0.4 0.1 3.3 0.6 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 101.7;Gastric mucus-secreting cells: 356.8;Prostatic glandular cells: 106.4;Respiratory ciliated cells: 100.6;Urothelial cells: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 53.2;RT4: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" 1.1 1.6 16.2 2.8 15.4 3.6 17.6 21.2 21.9 2.9 18.0 15.2 6.3 2.7 10.2 7.1 6.3 12.6 1.1 13.9 9.2 5.3 2.4 8.2 1.5 10.0 6.3 1.5 23.1 5.3 3.9 3.4 9.8 15.2 15.2 5.1 15.3 3.8 1.9 3.8 8.6 1.1 1.0 1.5 41.0 4.0 9.8 3.4 25.9 0.0 3.5 13.8 2.3 24.7 14.0 15.5 1.8 1.5 0.3 0.5 5.6 1.0 0.2 1.6 3.9 8.7 16.9 2.3 13.7 0.4 11.0 16.3 0.3 0.4 1.9 1.4 17.3 1.9 11.9 2.2 0.2 1.7 1.6 0.3 6.7 7.6 0.2 2.1 0.1 2.4 2.5 16.8 0.2 27.2 2.3 1.8 10.5 53.2 6.1 2.5 4.8 6.0 18.0 38.5 5.6 8.3 2.8 26.8 1.1 6.7 22.9 2.0 2.6 2.6 14.6 2.1 1.7 11.3 10.1 1.4 5.8 1.0 3.0 6.5 2.0 1.9 3.7 1.4 3.5 3.9 3.5 2.9 1.1 5.3 3.8 3.3 9.8 3.6 1.6 3.8 2.9 0.7 16.2 15.4 21.2 21.9 13.9 9.2 10.0 6.3 9.8 1.0 9.8 24.7 0.7 76.9 101.7 0.3 1.1 0.8 5.4 7.9 4.0 1.1 61.3 21.1 0.6 42.9 59.7 9.2 4.2 5.5 0.5 61.8 7.9 35.4 0.6 39.7 7.9 4.5 3.6 0.8 1.0 37.4 10.3 5.7 356.8 88.2 22.1 0.4 0.7 1.7 0.8 0.0 0.6 85.7 48.8 0.0 0.4 2.1 0.3 4.2 1.8 4.7 1.6 0.1 0.0 0.0 0.2 46.2 40.0 0.0 1.5 106.4 10.4 8.3 100.6 1.3 0.0 0.7 2.8 0.5 4.8 28.2 0.9 7.5 3.1 1.2 35.7 107.7 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RASL10A RRP22 ENSG00000100276 "RAS like family 10 member A" Q92737 22 29312933-29319679 "Enzymes, Predicted intracellular proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 28.7" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Breast glandular cells: 35.9;Breast myoepithelial cells: 58.3;Excitatory neurons: 35.1;Rod photoreceptor cells: 19.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 3.4;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.6;NB-4: 2.5;U-2 OS: 1.1;U-266/70: 2.7;U-266/84: 1.0" "Group enriched" "Detected in many" 6 "amygdala: 33.7;basal ganglia: 16.7;cerebral cortex: 36.0;hippocampal formation: 26.3;white matter: 15.3" "Group enriched" "Detected in many" 4 "cerebral cortex: 35.6;hippocampal formation: 27.8" HPA056169 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA056169: AB_2683053" "unprognostic (1.94e-1)" "unprognostic (2.51e-4)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (7.99e-2)" "unprognostic (9.42e-2)" "unprognostic (1.61e-2)" "unprognostic (5.00e-4)" "unprognostic (2.44e-1)" "unprognostic (7.00e-4)" "unprognostic (3.12e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (3.61e-3)" 0.9 1.4 26.6 0.3 23.2 0.1 2.0 6.3 28.7 0.4 5.3 0.7 0.3 0.6 0.1 0.4 0.6 0.1 3.8 24.5 13.4 1.2 0.9 1.2 0.1 9.3 11.6 0.2 0.4 0.1 5.0 0.2 10.4 2.0 0.0 2.6 1.0 0.1 0.7 0.7 1.1 0.0 9.0 1.2 0.5 1.8 13.3 0.1 1.1 0.1 0.1 0.5 0.3 16.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.4 0.0 2.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.5 0.5 0.2 0.1 0.0 1.1 0.0 0.1 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 23.2 6.3 28.7 24.5 13.4 9.3 11.6 10.4 9.0 13.3 16.2 3.9 0.0 0.0 17.9 0.4 0.4 0.6 0.0 0.0 6.8 35.9 58.3 1.1 1.5 0.0 0.0 6.2 0.2 1.0 0.7 0.0 0.0 1.3 0.8 0.3 3.1 0.0 0.0 35.1 0.0 4.7 0.5 1.5 1.4 0.0 0.5 7.9 0.5 1.1 0.0 4.4 1.1 0.0 2.6 5.8 0.5 0.3 2.7 0.0 4.7 0.2 3.3 0.0 3.0 3.9 0.1 0.1 0.0 0.3 1.7 0.2 0.1 0.2 19.6 0.0 13.4 0.5 1.5 3.9 0.3 0.6 0.5 0.5 0.6 0.4 0.2 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RBFOX3 "FOX-3, HRNBP3, NeuN" ENSG00000167281 "RNA binding fox-1 homolog 3" A6NFN3 17 79089345-79516148 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.2;intestine: 97.4;urinary bladder: 80.5" "Group enriched" "Detected in many" 7 "Excitatory neurons: 320.4;Inhibitory neurons: 163.9;Skeletal myocytes: 124.4" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Group enriched" "Detected in many" 4 "cerebellum: 217.2;cerebral cortex: 118.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 16.1;NTERA-2: 14.2;SCLC-21H: 22.4;U-2 OS: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030790, HPA075862, CAB078782" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB078782: , HPA030790: AB_10602305, HPA075862: " "unprognostic (2.84e-1)" "unprognostic (1.88e-1)" "unprognostic (4.10e-2)" "unprognostic (9.23e-3)" "unprognostic (8.85e-2)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (7.72e-2)" "unprognostic (1.50e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.22e-15)" "unprognostic (8.92e-3)" "unprognostic (1.92e-1)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" 0.5 0.9 11.8 0.4 29.7 0.6 0.3 217.2 118.3 3.0 0.0 97.4 1.5 39.9 3.1 9.6 3.6 0.0 0.3 23.6 0.0 0.3 0.2 0.6 0.1 12.3 1.1 1.3 0.5 0.9 7.5 0.0 13.4 22.3 2.4 3.4 0.2 24.4 0.5 0.5 9.1 9.5 0.0 0.5 4.2 7.5 0.0 0.0 0.3 0.0 0.0 80.5 8.2 40.2 0.0 16.1 0.2 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 14.2 0.0 0.2 0.3 0.7 0.1 0.0 0.0 22.4 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.9 0.0 0.4 0.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.8 29.7 217.2 118.3 23.6 0.0 12.3 1.1 13.4 0.0 0.0 40.2 0.5 0.0 0.0 5.9 0.2 2.0 8.1 0.0 0.0 11.5 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 5.7 0.3 0.4 7.5 0.0 0.0 320.4 0.0 0.1 11.8 0.0 0.7 0.0 0.1 0.0 0.2 0.1 5.0 163.9 0.0 0.0 0.6 5.5 10.1 0.3 7.6 5.4 10.3 0.0 1.2 2.1 11.1 4.8 0.0 0.0 10.5 0.0 15.2 0.0 0.1 0.0 3.1 0.0 124.4 7.5 2.4 26.4 0.0 1.4 0.1 2.3 0.1 0.0 2.8 RBM24 "dJ259A10.1, FLJ30829, RNPC6" ENSG00000112183 "RNA binding motif protein 24" Q9BX46 6 17281361-17293871 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 142.1;skeletal muscle: 313.0;tongue: 105.7" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 193.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 58.7;RH-30: 59.7;T-47d: 28.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA066927, HPA067231" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA066927: AB_2685750, HPA067231: AB_2685808" "unprognostic (9.05e-3)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-3)" "unprognostic (1.53e-1)" "unprognostic (4.54e-4)" "unprognostic (3.34e-2)" "unprognostic (1.33e-2)" "unprognostic (2.97e-3)" "unprognostic (3.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-2)" "unprognostic (3.06e-2)" "unprognostic (1.08e-2)" "unprognostic (2.33e-4)" 5.4 0.5 3.7 1.7 4.1 0.1 3.7 0.1 5.7 13.9 2.5 9.7 1.6 31.2 16.8 7.4 24.0 2.6 142.1 4.5 4.9 0.9 1.1 1.3 0.5 1.6 1.9 2.1 0.2 2.1 5.5 0.6 0.7 9.9 7.4 0.4 4.1 5.8 313.0 1.4 3.6 29.3 0.6 1.2 2.1 4.2 3.0 0.8 2.1 105.7 0.3 8.8 3.6 2.2 1.5 9.3 12.0 0.0 0.0 0.0 0.0 18.7 6.8 12.4 13.0 0.0 1.1 0.0 5.7 13.4 19.5 0.0 11.5 0.4 22.3 0.0 0.4 0.0 1.0 6.4 0.5 0.0 1.1 6.4 0.0 2.4 0.5 15.8 1.6 0.0 0.0 0.0 58.7 2.8 0.0 0.2 4.1 0.0 1.4 0.1 59.7 0.0 0.0 0.0 7.8 0.9 0.2 0.0 0.2 9.3 28.2 0.4 0.0 4.2 10.0 0.0 16.2 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 4.1 0.1 5.7 4.5 4.9 1.6 1.9 0.7 0.6 3.0 2.2 1.1 0.0 0.0 0.0 0.0 1.1 0.2 1.1 0.0 2.3 3.2 0.8 193.2 0.0 1.8 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.6 33.5 13.6 1.5 4.8 0.0 11.6 0.0 13.4 6.4 0.0 9.9 1.3 0.5 0.4 0.0 0.3 1.7 6.6 4.5 0.0 0.0 0.7 1.9 0.0 0.3 1.8 1.9 0.0 0.7 0.0 0.5 0.4 0.3 2.2 0.7 0.0 0.3 0.0 0.6 21.9 0.0 6.6 23.9 19.7 0.4 7.3 0.2 1.0 0.8 0.5 0.0 3.0 0.1 RBM38 "dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D" ENSG00000132819 "RNA binding motif protein 38" Q9H0Z9 20 57391396-57409333 "Predicted intracellular proteins" "Cell cycle, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 136.4;skeletal muscle: 221.7" "Cell type enhanced" "Detected in many" "B-cells: 110.9;dendritic cells: 156.9;Erythroid cells: 280.4" "Cancer enhanced" "Detected in all" "ovarian cancer: 95.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 140.6;U-698: 150.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB017036 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB017036: " "unprognostic (1.03e-1)" "prognostic favorable (3.64e-7)" "unprognostic (3.71e-2)" "unprognostic (7.73e-3)" "unprognostic (4.16e-2)" "unprognostic (4.85e-2)" "unprognostic (1.53e-2)" "unprognostic (4.37e-3)" "unprognostic (3.04e-1)" "unprognostic (9.04e-3)" "unprognostic (3.90e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.13e-2)" "unprognostic (2.29e-1)" "prognostic favorable (1.63e-4)" "unprognostic (1.83e-1)" 11.7 10.7 6.7 26.6 9.4 136.4 12.8 13.3 10.3 18.8 15.1 96.6 8.7 38.4 0.9 16.8 28.9 5.1 72.6 5.9 6.4 16.3 16.4 21.0 43.4 8.6 11.5 27.8 10.8 1.9 12.2 5.5 8.0 27.0 4.1 0.6 19.7 11.9 221.7 9.1 39.8 8.7 6.6 65.8 23.0 38.1 9.4 26.6 9.4 32.7 12.2 42.9 13.6 7.9 20.1 20.4 9.7 25.1 0.0 1.6 56.3 6.5 1.6 13.5 3.5 84.2 20.6 140.6 54.1 1.9 13.2 18.3 8.0 8.0 2.1 29.0 34.5 118.0 7.6 52.6 6.0 57.8 54.2 1.9 3.8 5.7 1.1 1.9 9.2 52.5 100.9 24.6 1.6 87.8 42.7 58.5 36.9 10.7 25.5 82.0 23.6 114.2 10.1 9.2 40.9 26.3 15.2 50.5 24.7 8.7 28.3 79.4 17.0 4.4 42.6 6.0 27.6 60.1 86.8 150.7 1.1 40.3 4.2 0.0 0.5 2.2 3.1 1.8 1.9 3.2 2.5 2.1 1.0 3.3 3.0 2.8 0.7 3.5 1.7 1.3 4.7 2.1 6.7 9.4 13.3 10.3 5.9 6.4 8.6 11.5 8.0 6.6 9.4 7.9 13.9 3.2 5.2 10.1 110.9 9.1 28.3 7.9 13.6 1.0 15.8 21.0 42.5 8.6 6.6 1.8 0.0 1.9 156.9 41.6 9.8 6.2 4.2 54.2 5.2 11.9 62.8 280.4 2.5 5.0 5.8 8.8 12.2 21.5 8.8 31.5 10.4 6.0 9.6 0.0 1.3 56.4 12.2 8.1 18.9 4.0 4.4 27.6 1.8 2.8 5.8 12.8 54.6 4.5 4.6 5.9 35.4 6.0 52.8 18.8 2.8 16.4 22.5 1.4 6.6 20.6 7.6 2.4 13.2 9.1 8.4 2.3 81.0 13.3 34.0 18.5 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Group enriched" "Detected in many" 4 "Granulosa cells: 5988.6;Theca cells: 3228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SH-SY5Y: 835.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" 23.7 377.1 64.6 18.4 65.2 1.3 49.5 64.9 72.7 53.8 251.4 30.3 32.3 180.2 64.2 35.4 390.2 182.9 60.1 65.5 67.8 46.9 140.8 26.8 18.6 83.1 69.0 1366.7 632.7 46.8 257.8 63.6 64.7 44.8 14.2 23.2 50.2 41.3 15.2 31.3 26.2 119.3 68.2 47.0 29.3 56.1 75.2 9.4 23.0 15.5 12.0 65.7 24.3 67.5 7.8 2.9 7.4 164.2 0.3 0.0 0.9 0.1 0.0 0.0 0.1 0.4 76.1 0.0 53.8 0.1 2.6 0.1 38.2 0.5 0.0 0.1 5.3 0.1 2.7 75.5 155.1 0.2 0.1 3.0 0.0 0.1 0.0 160.9 0.0 0.0 0.2 29.9 0.2 0.0 0.2 0.5 18.4 0.2 0.0 0.1 32.0 0.5 0.1 0.1 19.6 835.4 35.3 0.1 0.1 13.9 3.2 1.1 0.0 0.3 120.0 0.2 0.3 0.6 0.5 0.5 1.3 0.0 2.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 64.6 65.2 64.9 72.7 65.5 67.8 83.1 69.0 64.7 68.2 75.2 67.5 24.8 32.1 5.9 8.8 3.5 17.6 53.5 91.9 2.8 26.3 70.4 47.8 21.4 77.2 30.3 23.9 2.1 3.2 1.0 0.1 13.7 1013.0 4.8 199.6 961.4 103.8 43.1 13.5 0.5 1042.7 6.2 158.8 19.9 58.1 0.0 5988.6 343.7 6.9 16.5 3.3 0.3 2.3 42.7 10.6 3.4 16.2 27.1 25.1 8.8 5.6 13.5 159.9 0.0 4.0 16.0 563.0 0.0 4.5 2.9 56.6 2.6 4.7 10.3 7.2 26.3 220.9 534.7 11.6 4.9 6.2 34.9 3.8 10.2 3228.5 2.7 32.7 RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 324.1;RPTEC TERT1: 232.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA056999: AB_2683306" "unprognostic (1.65e-1)" "unprognostic (7.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.23e-3)" "unprognostic (8.66e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-2)" "unprognostic (3.47e-3)" "unprognostic (4.63e-2)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (2.88e-2)" "unprognostic (1.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.52e-1)" "unprognostic (4.91e-2)" "unprognostic (2.16e-3)" 238.3 96.7 22.3 43.8 28.0 1.4 194.8 20.2 24.1 196.9 26.7 350.6 25.2 200.7 90.0 99.9 200.5 95.4 174.7 17.3 25.2 218.7 108.9 119.6 23.3 23.1 27.6 190.0 68.8 68.6 33.0 105.0 28.7 182.6 46.6 10.4 92.1 193.7 31.2 56.6 107.7 171.9 18.7 56.7 159.8 45.4 33.2 23.5 140.7 31.6 20.0 323.4 134.0 18.9 0.7 54.5 58.5 0.4 324.1 96.4 145.8 74.8 101.8 90.2 74.6 76.2 31.2 0.5 39.3 96.7 82.5 29.9 68.0 54.4 107.9 0.1 14.6 1.8 24.7 80.5 139.4 0.5 12.0 112.8 13.8 86.7 11.5 100.8 52.8 2.5 0.5 0.4 44.6 32.6 0.3 1.2 150.9 62.3 34.6 3.5 16.2 4.7 232.2 88.9 1.1 11.6 7.7 55.2 37.7 192.3 11.7 0.0 48.8 44.3 4.2 77.3 12.8 0.1 0.2 0.4 72.8 0.2 20.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 22.3 28.0 20.2 24.1 17.3 25.2 23.1 27.6 28.7 18.7 33.2 18.9 104.0 54.5 98.9 36.6 4.5 9.3 61.8 22.7 14.2 6.7 45.8 64.3 114.4 75.8 48.5 141.6 2.1 108.7 4.1 1.8 113.5 100.0 104.7 31.2 86.3 69.7 1.8 5.0 6.4 94.8 184.8 66.7 18.8 48.2 10.1 18.0 44.3 55.2 39.9 0.0 5.2 0.1 20.3 1.9 10.2 31.5 171.2 4.3 14.2 71.2 2.1 1.0 1.0 2.0 1.6 67.0 0.0 180.2 0.5 101.5 2.0 242.2 30.9 5.7 111.7 6.6 149.9 35.3 22.0 27.8 8.0 41.2 4.4 28.1 1.0 151.7 RBPMS2 ENSG00000166831 "RNA binding protein, mRNA processing factor 2" Q6ZRY4 15 64739891-64775589 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 300.8;intestine: 147.2" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 215.3" "Cancer enriched" "Detected in all" 4 "testis cancer: 37.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.0;AN3-CA: 55.4;HEL: 86.2;NTERA-2: 76.4;SuSa: 86.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" "unprognostic (1.07e-2)" "unprognostic (6.79e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (4.51e-2)" "unprognostic (6.41e-2)" "unprognostic (5.86e-2)" "unprognostic (2.21e-2)" "unprognostic (4.47e-2)" "prognostic favorable (1.48e-4)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 20.0 4.9 5.2 6.7 6.1 1.6 12.5 2.7 4.7 18.4 14.7 147.2 6.0 53.1 7.5 20.3 30.8 9.9 300.8 3.7 4.3 17.8 13.9 7.6 1.0 3.3 5.0 10.6 2.7 16.5 4.1 7.7 3.0 27.5 8.1 2.0 2.5 45.8 5.6 4.9 30.2 37.6 2.9 4.4 51.9 6.4 12.6 2.5 13.8 4.9 0.6 94.0 14.4 3.2 0.0 6.3 39.0 55.4 0.0 0.0 5.9 1.2 0.2 7.0 1.6 4.9 0.5 0.0 5.2 1.1 6.5 0.0 28.8 0.0 2.6 0.0 9.0 86.2 9.5 9.9 3.7 0.0 0.7 0.1 0.0 4.4 0.0 1.5 0.7 1.9 0.5 0.0 0.5 2.9 0.0 0.3 76.4 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 13.5 8.5 0.1 1.6 86.5 7.9 0.3 0.0 0.0 28.4 3.7 3.7 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 5.2 6.1 2.7 4.7 3.7 4.3 3.3 5.0 3.0 2.9 12.6 3.2 3.1 0.0 0.0 0.0 1.1 0.8 0.3 0.0 0.6 0.3 0.5 0.5 215.3 0.0 0.0 3.7 0.0 0.6 2.0 0.0 9.8 0.4 4.7 0.4 3.4 6.4 0.0 7.4 0.3 1.6 1.1 11.1 5.1 0.7 0.0 0.9 2.9 8.5 0.3 0.0 0.2 0.0 0.0 1.3 1.3 1.0 3.7 10.4 1.8 1.0 0.2 3.3 9.2 0.0 0.0 1.2 0.0 6.4 0.0 1.5 0.0 31.0 0.0 1.7 46.0 1.7 51.0 0.8 14.1 0.3 1.1 3.1 0.7 1.0 0.0 0.2 RCAN3 DSCR1L2 ENSG00000117602 "RCAN family member 3" Q9UKA8 1 24502351-24541040 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 33.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 88.0;Enteroendocrine cells: 82.1;T-cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 38.2" "Lineage enriched" "Detected in all" 7 "T-cells: 38.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034533, HPA064289" Enhanced Approved "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli fibrillar center" "HPA034533: AB_10601481, HPA064289: AB_2685232" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (4.01e-2)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "unprognostic (4.20e-3)" "unprognostic (3.41e-3)" "unprognostic (3.66e-2)" "unprognostic (6.42e-2)" "unprognostic (2.47e-1)" "unprognostic (1.72e-3)" "unprognostic (7.44e-2)" "unprognostic (3.52e-3)" "unprognostic (9.83e-2)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "unprognostic (4.71e-2)" 3.7 1.9 3.3 12.3 4.0 7.0 7.1 27.0 4.7 4.5 3.2 6.7 6.9 3.0 6.4 12.4 14.4 5.5 3.4 1.8 7.3 3.9 1.7 8.0 19.9 9.3 7.3 0.6 15.7 6.3 6.3 2.1 9.3 33.8 6.7 11.5 11.6 2.3 1.8 11.2 6.1 3.5 4.5 9.3 17.2 2.1 6.6 16.1 12.3 3.0 19.5 7.0 6.0 6.9 17.6 13.9 0.2 4.3 3.5 8.4 15.6 11.8 6.4 9.5 9.0 4.3 23.0 13.1 10.8 19.9 7.4 16.4 12.0 14.8 10.2 12.9 7.3 1.4 3.8 13.1 2.2 4.6 11.5 2.9 10.8 3.8 4.6 7.9 1.9 16.2 2.0 0.5 4.1 6.3 12.1 6.7 17.7 13.4 10.2 4.7 0.2 0.4 6.9 17.9 35.6 8.8 9.7 12.0 37.2 7.9 12.8 8.9 13.6 11.2 13.2 0.6 8.2 18.2 22.8 17.5 4.5 18.0 12.9 3.5 1.8 2.2 1.2 1.0 10.0 5.2 24.9 9.0 3.0 5.1 33.1 17.7 0.6 4.0 0.4 2.1 38.2 7.9 3.3 4.0 27.0 4.7 1.8 7.3 9.3 7.3 9.3 4.5 6.6 6.9 19.7 19.2 13.3 0.0 32.4 14.1 27.3 8.9 11.4 43.0 29.9 36.8 6.4 25.8 15.8 20.2 64.6 4.0 18.9 16.4 13.7 19.0 1.2 88.0 6.8 8.6 82.1 2.5 1.6 28.2 10.3 6.0 26.5 34.1 16.5 14.8 7.1 2.2 8.5 25.2 6.7 14.4 14.2 8.4 28.0 0.0 1.8 23.0 30.2 5.6 31.5 9.1 6.2 0.0 21.2 43.2 11.3 1.2 22.0 53.9 4.3 1.0 67.7 34.5 0.0 4.7 10.4 0.7 17.5 26.9 21.7 5.3 106.8 0.1 12.2 26.3 RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.7;Fibroblasts: 105.1;Leydig cells: 38.2;Peritubular cells: 44.8;Smooth muscle cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cell line enhanced" "Detected in many" "AN3-CA: 166.6;ASC diff: 283.3;ASC TERT1: 175.4;BJ: 353.8;BJ hTERT+ SV40 Large T+ RasG12V: 179.6;fHDF/TERT166: 304.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" 67.9 35.3 15.8 33.6 17.2 6.8 48.2 15.5 24.1 78.8 23.5 43.5 39.9 47.4 4.4 11.4 41.4 25.2 56.7 16.0 19.1 41.2 62.3 40.8 8.7 17.4 17.0 50.0 16.4 3.9 20.7 31.1 19.0 32.4 11.4 1.4 19.1 12.1 11.7 25.3 43.2 25.7 16.8 65.9 23.4 17.2 24.5 4.0 26.4 7.5 4.1 43.2 46.3 18.8 3.2 4.3 2.7 166.6 283.3 175.4 1.9 353.8 86.5 122.0 179.6 4.2 1.3 1.3 19.5 304.0 1.3 0.3 6.8 0.5 49.2 0.1 2.5 19.5 1.5 9.1 105.7 0.1 43.0 119.5 0.2 93.2 0.4 3.2 43.8 2.3 8.7 1.0 87.8 2.9 0.1 2.0 1.4 8.8 24.5 0.5 3.9 4.0 1.4 0.0 1.7 10.5 0.3 1.1 0.3 2.8 1.3 11.5 121.4 1.7 52.4 135.3 0.1 14.9 44.5 2.6 7.9 9.6 13.4 0.0 0.2 1.6 0.7 0.0 0.7 0.4 1.7 0.6 0.4 0.2 6.8 2.3 2.5 1.8 0.3 0.2 1.6 1.1 15.8 17.2 15.5 24.1 16.0 19.1 17.4 17.0 19.0 16.8 24.5 18.8 12.0 0.0 6.1 4.6 2.8 18.6 0.6 2.9 3.4 0.8 1.7 3.3 2.1 1.5 0.8 1.8 0.0 2.5 1.4 10.5 1.9 1.6 2.2 1.5 54.7 10.6 1.2 0.0 1.0 0.5 5.0 105.1 6.6 1.6 1.3 7.0 27.1 3.7 22.6 1.7 1.1 7.6 0.0 11.4 23.2 3.0 38.2 11.9 10.6 10.3 3.1 0.6 0.0 1.5 0.8 1.5 7.9 44.8 4.8 0.9 13.1 0.6 0.9 0.8 13.1 37.5 66.5 6.5 6.8 2.8 13.9 6.2 2.2 17.2 8.0 0.4 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 343.8" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 15 "basophil: 86.7" "Lineage enriched" "Detected in many" 39 "granulocytes: 86.7" "Cell line enhanced" "Detected in many" "K-562: 44.7;U-266/70: 42.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: AB_10965790, HPA040868: AB_10963549, HPA066145: " "unprognostic (2.39e-1)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (6.24e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-2)" "unprognostic (8.24e-2)" "unprognostic (4.72e-2)" "unprognostic (2.42e-4)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-2)" 2.3 1.8 1.4 1.8 1.4 11.6 3.6 1.6 2.0 1.7 0.4 2.1 2.9 2.2 1.2 2.3 4.2 1.6 3.4 1.4 2.3 1.2 1.8 1.0 2.9 1.7 1.1 1.9 1.7 40.0 0.9 1.5 1.6 5.3 3.0 4.2 1.7 1.3 1.0 2.2 2.1 2.7 0.8 1.0 5.0 343.8 2.2 7.4 0.9 1.3 2.6 2.0 1.6 2.1 11.3 6.5 10.1 4.5 4.2 7.5 3.4 7.6 8.4 8.2 8.9 4.7 10.0 7.0 11.5 6.7 5.7 5.7 7.7 3.4 8.5 6.5 4.9 11.7 10.2 6.7 0.8 17.2 16.4 3.8 1.5 9.7 12.4 3.5 2.8 0.0 44.7 29.8 20.5 15.1 2.8 13.5 5.5 4.6 6.6 14.0 18.8 12.6 2.5 4.0 8.6 9.7 7.3 9.6 2.4 2.9 16.2 14.8 1.4 6.1 5.4 8.2 9.3 42.5 31.1 2.7 12.6 22.3 5.6 86.7 0.4 5.7 0.3 0.1 0.4 0.0 0.4 0.4 0.7 0.0 0.1 0.3 0.4 2.2 0.2 0.2 1.8 0.4 1.4 1.4 1.6 2.0 1.4 2.3 1.7 1.1 1.6 0.8 2.2 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 0.0 1.3 0.0 0.0 3.2 0.8 0.0 0.0 1.6 0.0 2.8 1.6 0.6 0.0 0.0 0.0 1.5 2.4 1.5 0.0 1.7 1.3 26.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.5 4.7 0.0 0.0 RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;retina: 3.0" "Group enriched" "Detected in some" 7 "Early spermatids: 9.1;Hepatic stellate cells: 8.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.5;HMC-1: 2.7;Karpas-707: 3.0;SH-SY5Y: 3.7;SiHa: 1.8;THP-1: 3.5" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (4.54e-1)" "unprognostic (6.63e-8)" "unprognostic (3.14e-3)" "unprognostic (1.89e-1)" 0.1 2.9 2.5 0.2 2.3 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.3 0.1 0.0 1.3 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.5 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.1 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 2.5 2.3 0.0 10.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.4 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 10.2;prostate: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 17.6;Inhibitory neurons: 8.6" "Cancer enriched" "Detected in single" 15 "prostate cancer: 5.6" "Region enriched" "Detected in many" 4 "cerebral cortex: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (3.81e-2)" "unprognostic (4.05e-2)" "unprognostic (8.29e-2)" "unprognostic (9.66e-3)" "unprognostic (2.54e-1)" "unprognostic (9.90e-2)" "unprognostic (2.59e-1)" "unprognostic (6.02e-3)" "unprognostic (2.22e-2)" "unprognostic (3.44e-2)" "unprognostic (8.64e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.04e-4)" "unprognostic (6.02e-2)" "unprognostic (3.28e-2)" "unprognostic (5.62e-7)" "unprognostic (3.50e-2)" 0.0 0.5 1.5 0.0 1.9 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 0.0 0.1 1.7 0.7 0.3 0.0 0.0 0.1 0.0 1.7 3.8 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 10.2 2.3 0.9 1.7 0.7 1.7 0.0 1.0 1.6 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.7 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 164.4" "Group enriched" "Detected in some" 4 "dendritic cells: 23.8;Early spermatids: 18.1;NK-cells: 52.5;T-cells: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 393.6;neutrophil: 516.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 516.3" "Group enriched" "Detected in many" 5 "MOLT-4: 26.3;U-937: 61.0" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA035979: AB_10673227" "unprognostic (1.48e-4)" "unprognostic (2.75e-4)" "unprognostic (4.44e-2)" "unprognostic (1.11e-4)" "unprognostic (3.10e-1)" "unprognostic (2.93e-4)" "unprognostic (4.92e-2)" "unprognostic (2.06e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-1)" "unprognostic (4.25e-2)" "unprognostic (3.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-2)" "unprognostic (1.26e-1)" "unprognostic (1.07e-3)" 3.8 3.1 0.1 7.6 0.2 164.4 0.5 2.0 0.8 0.3 0.3 1.2 4.1 3.1 0.0 1.9 0.9 4.6 2.8 0.2 0.0 1.5 1.3 4.8 11.5 0.6 0.1 3.9 3.4 0.1 0.5 1.7 1.0 1.4 1.1 10.6 4.6 0.2 3.0 5.6 4.1 0.6 0.1 19.8 2.4 3.8 0.1 8.4 3.1 0.9 8.1 3.8 0.5 1.1 1.6 0.5 5.8 2.5 0.0 0.0 2.5 1.8 0.0 0.0 0.0 1.3 1.1 1.9 0.4 0.0 1.0 2.8 0.0 0.0 0.0 2.0 3.6 0.9 2.5 0.3 0.0 3.4 3.8 0.0 0.0 0.0 0.0 2.9 0.0 2.0 2.1 3.0 0.0 1.0 26.3 3.6 0.4 0.6 0.8 9.3 2.0 1.4 0.0 1.7 1.8 2.7 1.7 3.7 0.6 3.1 1.2 2.0 2.5 3.2 1.9 2.2 1.1 5.3 0.8 1.3 1.9 61.0 1.6 98.0 2.9 393.6 57.4 20.8 59.6 6.5 74.1 66.2 5.4 5.2 104.6 93.8 516.3 35.2 84.6 0.7 114.2 37.4 0.1 0.2 2.0 0.8 0.2 0.0 0.6 0.1 1.0 0.1 0.1 1.1 0.7 0.0 4.4 0.3 5.9 0.9 0.0 0.0 0.0 0.5 0.4 0.5 0.5 1.5 1.3 0.0 2.1 0.0 23.8 0.0 0.0 2.4 18.1 0.1 0.3 0.3 0.0 8.8 0.4 1.7 0.1 0.6 2.6 0.2 1.3 0.1 0.4 0.3 0.1 1.7 0.5 0.0 0.0 1.6 0.7 2.0 0.0 3.5 1.8 0.0 2.5 0.0 52.5 0.5 0.4 2.2 0.0 0.0 3.4 0.0 0.0 0.3 0.0 2.8 0.0 0.3 0.5 5.9 0.0 0.0 0.3 0.0 51.8 0.1 0.1 0.1 RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 25.4" "Cell type enriched" "Detected in some" 4 "Macrophages: 527.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.1" "Group enriched" "Detected in some" 5 "HEL: 60.2;HL-60: 46.7;NB-4: 43.6;U-937: 39.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 340000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "HPA028727: AB_2797219, HPA045780: AB_10962728" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (8.66e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-2)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.30e-3)" "unprognostic (8.21e-3)" "unprognostic (2.81e-4)" "unprognostic (1.73e-2)" "unprognostic (9.91e-2)" 4.3 2.3 0.7 14.1 0.6 13.2 2.3 0.9 0.7 2.4 0.9 2.4 2.9 1.0 0.5 1.9 1.3 5.3 0.8 0.6 1.2 1.0 5.3 4.1 8.4 1.5 1.0 0.8 0.8 0.4 0.3 2.2 1.5 1.1 2.9 0.6 0.7 1.0 0.9 0.4 5.8 2.9 1.3 25.4 1.9 0.4 0.8 4.2 0.8 3.1 4.4 4.8 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.2 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 39.9 0.0 195.5 50.7 353.1 0.8 66.7 6.8 0.1 0.8 1.3 51.0 0.2 0.1 0.2 164.8 0.6 82.1 12.0 0.0 94.4 0.7 0.6 0.9 0.7 0.6 1.2 1.5 1.0 1.5 1.3 0.8 1.6 0.3 6.4 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.0 1.8 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 16.0 0.0 0.0 0.0 0.8 0.0 0.0 24.7 0.0 5.7 1.1 7.3 0.0 0.0 0.0 0.0 124.9 27.3 0.8 0.3 527.4 0.0 15.9 128.3 0.1 28.8 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.3 1.5 0.3 13.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 7.6 0.0 0.1 0.0 RGS2 G0S8 ENSG00000116741 "Regulator of G protein signaling 2" P41220 1 192809039-192812275 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Translation regulation" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 1871.8;Langerhans cells: 637.8;Macrophages: 621.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 3268.4;neutrophil: 4374.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 4374.2" "Cell line enhanced" "Detected in many" "hTCEpi: 141.8;hTERT-HME1: 96.8;Karpas-707: 94.0;PC-3: 226.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013385 Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA013385: AB_2668827" "prognostic favorable (2.43e-4)" "unprognostic (9.75e-2)" "unprognostic (1.28e-3)" "unprognostic (4.43e-2)" "unprognostic (1.79e-1)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (6.49e-2)" "prognostic unfavorable (2.90e-5)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.16e-1)" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" 129.3 353.8 36.4 241.4 40.7 565.0 126.8 41.8 82.6 67.2 56.7 328.5 142.7 217.4 96.0 256.2 149.2 189.5 73.0 43.6 47.7 53.6 66.3 123.6 37.1 50.3 43.9 137.4 513.3 12.5 198.7 100.1 46.0 182.2 110.1 36.9 27.5 222.4 10.0 37.3 104.9 505.9 41.0 192.1 113.4 18.8 47.5 47.3 22.8 63.7 17.3 259.8 71.7 42.1 0.0 20.1 25.4 2.4 48.9 7.7 1.5 9.9 12.4 3.2 3.4 17.9 11.8 1.7 2.8 9.3 2.5 9.7 16.7 17.5 2.9 2.6 12.3 4.8 12.9 0.4 21.5 12.1 2.8 8.1 141.8 6.5 96.8 18.1 23.9 9.1 4.4 94.0 10.0 0.3 6.6 16.8 34.0 1.9 226.6 6.7 5.9 5.4 16.9 16.3 9.4 47.4 7.1 0.5 11.8 26.0 0.7 6.0 6.7 4.8 4.5 5.2 5.2 55.4 1.7 5.3 67.3 2.4 17.8 3268.4 517.9 754.6 14.3 200.8 32.1 6.4 10.2 10.4 118.8 3.3 5.2 6.6 4374.2 2.3 362.7 16.0 6.7 310.2 36.4 40.7 41.8 82.6 43.6 47.7 50.3 43.9 46.0 41.0 47.5 42.1 22.3 51.3 195.9 6.8 187.2 42.3 47.3 45.0 6.2 18.7 138.5 44.1 69.4 7.2 46.1 136.1 18.8 227.6 145.1 27.0 0.0 33.5 24.6 6.9 51.5 38.6 349.2 3.2 6.6 30.3 24.5 125.8 38.7 7.5 1871.8 2.3 18.5 3.1 374.4 21.9 8.4 96.9 42.7 345.0 637.8 18.3 16.4 621.2 88.9 8.4 305.0 41.5 25.7 3.5 2.4 14.8 60.3 62.8 135.9 36.3 141.5 2.5 20.4 39.0 0.0 61.4 55.5 4.2 16.9 6.1 31.1 124.2 346.1 16.6 32.3 11.3 RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 619.6;Late spermatids: 1623.3" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" 2.7 0.9 1.7 0.0 2.4 0.0 0.6 1.0 1.5 1.4 10.4 0.3 0.0 2.9 1.1 0.3 10.6 1.2 0.3 1.1 3.9 0.2 0.1 1.7 0.3 5.9 7.4 7.3 0.5 0.0 1.1 0.5 3.7 1.3 0.1 1.0 0.1 2.3 0.1 0.6 0.1 1.5 3.7 0.0 0.1 61.3 5.3 0.1 0.3 0.1 0.3 0.4 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.3 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.0 1.5 1.1 3.9 5.9 7.4 3.7 3.7 5.3 2.9 0.1 0.0 0.0 14.4 0.0 2.2 0.0 1.6 0.6 1.2 1.2 0.8 0.8 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 619.6 58.1 14.2 0.7 0.0 0.0 2.3 0.0 0.2 8.6 0.5 0.8 0.0 1.3 0.0 0.0 0.2 0.0 1.6 0.0 4.1 0.0 2.9 1623.3 131.4 0.4 0.0 6.5 0.0 10.9 0.0 20.1 2.5 0.0 0.0 62.8 0.0 0.0 0.0 0.0 77.2 0.2 0.0 0.4 1.6 70.9 11.1 0.1 2.0 0.8 0.4 8.3 0.0 0.1 RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Sertoli cells: 5114.5;Smooth muscle cells: 1592.3" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1303.0;OE19: 692.4;SH-SY5Y: 4234.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" 138.1 312.4 75.5 29.7 87.2 0.1 58.4 84.2 136.5 160.5 73.1 95.7 64.5 73.7 63.1 71.8 65.5 142.7 238.2 65.9 90.7 88.1 34.1 55.5 33.8 95.6 89.1 19.5 30.6 83.3 45.4 19.9 108.2 75.1 42.9 15.3 27.8 190.0 116.5 21.8 75.8 278.0 68.8 16.7 93.5 40.5 99.6 21.2 164.7 236.8 39.4 136.1 60.5 83.7 0.4 0.0 62.9 8.0 1.3 3.0 2.6 1.1 4.4 2.0 1.3 5.3 1.6 0.5 9.2 1.1 0.7 0.4 0.8 0.8 3.3 3.0 1.0 1.3 0.9 0.1 2.6 0.8 0.7 2.0 1.9 2.1 2.6 14.3 1303.0 0.3 0.2 1.2 4.7 0.0 0.9 2.2 38.7 692.4 1.4 0.4 0.1 3.6 0.7 0.0 5.2 4234.9 0.9 0.0 1.5 185.8 0.0 1.3 5.3 1.0 2.3 0.9 2.0 1.5 1.2 0.4 1.4 0.2 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.2 0.1 0.2 0.4 0.4 0.1 0.2 0.1 0.0 0.2 0.1 75.5 87.2 84.2 136.5 65.9 90.7 95.6 89.1 108.2 68.8 99.6 83.7 458.3 3.2 5.6 61.4 1.7 17.1 6.0 1.0 0.6 1.8 9.8 12.1 0.0 0.0 7.3 1.8 4.2 1.5 2.4 0.3 1.9 1.0 32.7 3.4 11.6 353.7 0.0 0.0 24.4 1.1 0.8 43.0 223.3 8.1 1.3 0.9 0.0 0.0 1.2 0.0 60.5 0.2 0.0 0.0 26.3 17.0 6.8 11.9 23.2 80.6 0.6 2.6 0.0 25.1 69.7 3.9 0.2 2.6 0.4 12.7 0.2 2.5 5.9 5.8 5114.5 44.9 1592.3 5.7 1.7 5.2 12.6 1.2 5.8 5.5 0.2 7.0 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 74.6;Club cells: 44.8;Distal enterocytes: 52.2;Ionocytes: 46.8;Oligodendrocytes: 53.9;Pancreatic endocrine cells: 53.0;Urothelial cells: 49.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 12.7;CAPAN-2: 41.7;HaCaT: 21.7;RT4: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 2.2 0.4 4.1 1.7 8.8 0.4 2.0 5.6 7.1 4.3 0.3 18.0 1.3 0.6 0.2 24.4 1.1 3.4 7.7 4.0 4.9 0.9 0.4 1.0 0.8 10.0 9.5 0.3 0.6 0.3 1.3 1.1 7.3 1.8 18.0 1.1 7.8 0.5 0.5 16.6 0.8 1.1 4.1 0.4 15.7 7.3 7.4 0.7 0.7 0.0 7.1 9.7 12.8 11.4 12.7 4.3 0.4 0.2 0.2 1.2 1.2 0.7 0.1 0.9 0.1 0.9 41.7 0.3 3.0 6.3 4.2 21.7 0.0 7.1 0.6 0.3 0.2 0.2 2.9 2.5 0.5 0.1 0.5 0.9 1.0 6.0 0.1 4.0 1.0 0.4 0.0 0.4 0.9 0.0 0.1 0.3 0.2 1.3 1.2 0.2 0.2 0.0 0.0 40.4 0.4 0.3 5.0 11.4 0.4 0.6 5.6 0.4 0.9 4.4 0.5 0.3 0.3 0.4 0.5 0.5 4.1 0.8 0.2 1.5 0.6 0.4 0.2 0.4 0.1 0.7 0.2 0.1 0.7 0.3 0.2 0.2 1.7 0.3 0.2 0.7 0.3 0.3 4.1 8.8 5.6 7.1 4.0 4.9 10.0 9.5 7.3 4.1 7.4 11.4 1.3 0.0 0.5 11.1 0.7 17.7 8.0 74.6 5.2 2.7 3.9 2.4 0.4 5.7 44.8 3.7 0.0 0.4 0.2 52.2 0.0 12.4 3.9 4.7 3.4 1.4 2.4 0.0 19.0 15.8 0.3 2.1 27.5 8.4 4.5 1.6 1.8 0.0 0.2 1.7 21.9 17.3 46.8 0.0 2.7 1.0 0.6 0.4 1.8 4.7 0.6 1.3 0.0 10.6 53.9 53.0 22.3 0.0 0.2 13.4 0.2 0.3 33.2 1.8 6.6 1.2 4.0 0.3 0.1 19.0 28.4 0.7 0.5 0.2 30.2 49.9 RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Cell type enriched" "Detected in many" 21 "Squamous epithelial cells: 1544.7" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.8;hTCEpi: 2.0;RT4: 1.2" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" 1.3 2.1 5.3 0.0 5.4 0.0 0.8 4.9 6.9 823.5 3.9 0.5 0.0 0.6 0.0 4022.4 0.7 0.7 1.4 5.1 4.9 117.4 3.4 0.3 0.0 4.8 4.9 0.8 3.2 0.0 4.3 0.0 4.8 3.4 0.0 2.5 593.6 0.8 1.0 14.6 0.9 0.3 5.1 0.6 3.5 1.3 5.0 0.8 0.5 0.0 461.7 3.7 1728.8 5.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.3 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.4 4.9 6.9 5.1 4.9 4.8 4.9 4.8 5.1 5.0 5.2 0.0 0.0 0.0 2.0 0.3 1.3 28.9 22.9 6.2 1.0 0.9 0.5 0.7 0.0 47.6 14.7 0.0 0.0 0.0 0.6 15.6 1.5 2.0 0.0 0.1 0.7 0.0 0.0 6.0 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 2.0 0.0 0.7 1.4 0.0 1.5 0.0 0.0 0.0 64.4 0.0 4.0 0.3 0.7 4.8 0.0 0.0 34.8 0.0 0.0 1.6 2.8 0.0 0.0 5.4 1.5 0.1 1544.7 17.8 0.0 0.3 0.0 0.2 70.5 RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Cell type enhanced" "Detected in many" "B-cells: 273.0;dendritic cells: 90.5;granulocytes: 141.8;NK-cells: 64.9;Plasma cells: 183.1;T-cells: 223.6" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 126.3;HMC-1: 92.5;JURKAT: 123.7;MOLT-4: 179.4;U-266/70: 65.5;U-266/84: 56.8;U-698: 116.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" 2.2 0.9 0.7 36.4 0.6 62.9 13.2 0.5 0.8 2.9 0.6 6.3 4.8 1.6 0.9 2.9 1.5 6.4 0.7 0.6 0.8 1.2 2.7 5.7 86.0 1.1 1.3 0.9 1.4 0.4 0.7 0.9 0.9 2.7 5.6 0.0 3.9 0.9 0.6 1.2 20.6 1.5 1.0 42.6 8.2 0.7 0.8 98.2 1.8 0.3 85.2 10.6 1.6 1.0 0.2 0.4 0.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 126.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 2.6 0.0 18.8 0.1 0.0 0.0 21.1 92.5 1.5 0.0 0.0 0.0 0.1 0.1 123.7 1.4 1.2 0.0 0.0 179.4 13.3 2.3 0.0 0.4 19.1 0.3 4.3 0.0 0.0 0.1 0.1 0.3 0.8 0.2 0.1 5.7 0.5 0.5 0.0 0.5 0.1 0.2 65.5 56.8 116.3 0.1 4.4 0.1 210.3 1.1 168.7 112.2 0.8 99.3 164.3 176.9 151.1 1.9 212.1 274.3 220.5 8.4 74.2 1.2 26.1 268.4 124.1 0.7 0.6 0.5 0.8 0.6 0.8 1.1 1.3 0.9 1.0 0.8 1.0 2.9 3.2 9.9 0.3 273.0 7.1 1.4 0.3 1.8 0.0 11.1 6.7 1.1 1.5 2.9 0.0 0.0 0.1 90.5 0.3 0.0 0.1 0.6 0.6 0.5 2.3 0.0 23.4 0.3 0.0 0.2 3.6 9.7 1.0 141.8 0.0 1.8 0.2 2.2 0.0 0.3 0.4 0.0 4.4 16.2 0.7 0.0 28.4 56.9 8.4 11.3 0.0 64.9 0.5 0.1 0.0 0.1 0.0 183.1 1.4 0.0 0.4 1.0 0.0 0.0 2.0 2.0 0.3 0.2 0.3 7.0 0.3 223.6 0.1 0.3 2.0 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.8;skin 1: 129.8;vagina: 92.2" "Cell type enhanced" "Detected in many" "Paneth cells: 142.3;Squamous epithelial cells: 375.0;Suprabasal keratinocytes: 283.0;Urothelial cells: 275.1" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-BR-3: 328.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053343 Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" 0.5 0.1 0.9 0.2 0.9 0.2 16.0 1.1 1.8 26.3 0.5 2.8 0.6 0.7 9.5 211.8 2.7 0.5 0.1 1.0 1.1 5.5 0.2 2.3 0.2 2.1 0.8 0.3 16.3 2.2 3.0 3.2 2.4 16.6 2.6 0.0 44.3 2.4 0.2 129.8 0.6 0.1 0.8 0.1 1.2 0.3 1.9 2.6 0.5 0.0 23.3 20.7 92.2 0.9 1.6 9.7 0.1 2.7 0.2 0.0 5.2 0.1 0.8 0.4 0.2 4.0 4.4 0.0 2.4 0.0 0.3 77.9 4.5 0.6 0.2 10.5 12.5 0.5 11.3 0.6 0.0 0.5 0.0 0.3 6.0 0.3 0.1 0.4 0.1 2.3 2.1 0.5 0.0 27.2 0.6 2.3 1.7 19.3 3.7 4.0 0.4 1.8 5.1 34.3 4.0 0.8 8.0 328.9 0.2 0.5 40.9 0.3 0.1 0.0 1.1 0.2 0.3 0.0 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.1 1.8 1.0 1.1 2.1 0.8 2.4 0.8 1.9 0.9 0.6 0.0 3.2 0.3 0.5 84.1 42.5 80.9 19.9 0.0 75.2 48.5 0.9 2.8 103.0 29.5 0.0 60.7 1.9 43.1 13.7 107.5 0.0 18.5 1.9 2.5 22.7 0.0 1.5 56.2 6.0 2.0 7.1 25.5 1.3 0.4 0.0 0.0 4.6 0.0 0.5 54.7 67.1 0.0 13.3 0.0 0.0 0.8 32.0 0.0 3.6 0.0 0.0 0.0 0.3 13.8 142.3 0.7 0.1 89.8 1.0 0.9 26.2 0.0 0.0 0.2 7.3 0.0 0.9 375.0 283.0 42.4 1.9 0.0 66.3 275.1 RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.0;Endometrial ciliated cells: 90.2;Gastric mucus-secreting cells: 94.8;Glandular and luminal cells: 108.8;Muller glia cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 52.4;OE19: 50.7;RPTEC TERT1: 52.9;SK-BR-3: 54.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA051749: AB_2681589" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.08e-3)" "unprognostic (2.32e-1)" "unprognostic (5.07e-3)" "unprognostic (3.01e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.22e-8)" "unprognostic (3.74e-2)" "unprognostic (4.44e-2)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" 3.0 0.8 5.5 4.4 5.9 0.0 12.7 5.8 6.6 8.4 7.8 23.6 21.7 5.4 2.4 1.2 15.0 13.6 1.5 5.2 5.8 14.5 19.6 4.1 1.3 6.3 6.9 1.7 12.4 16.9 4.8 8.2 6.1 27.1 19.0 20.2 19.4 2.2 0.3 10.5 17.8 1.8 5.1 0.9 35.2 0.7 7.2 1.9 5.4 0.9 2.6 11.5 1.1 6.4 28.6 52.4 4.9 8.6 1.0 0.1 24.5 6.6 5.0 10.0 10.5 45.9 28.6 0.0 41.1 3.7 8.8 13.5 15.9 5.8 12.4 13.2 9.7 3.2 5.9 17.9 6.6 0.0 4.1 1.2 11.5 8.4 4.7 7.6 1.3 1.2 7.2 0.0 3.0 24.4 0.1 2.9 10.5 50.7 8.4 0.0 6.0 5.6 52.9 14.0 11.0 5.8 11.2 54.5 13.4 13.9 15.2 1.4 0.7 0.1 12.7 3.6 11.2 6.3 4.6 2.1 1.6 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.9 5.8 6.6 5.2 5.8 6.3 6.9 6.1 5.1 7.2 6.4 0.3 22.4 1.1 20.2 3.9 1.3 6.3 6.2 7.4 1.9 30.4 15.4 0.9 17.2 14.7 12.9 12.5 18.2 2.1 61.0 3.9 31.0 0.4 90.2 11.1 1.1 4.8 0.0 1.3 13.1 6.8 6.4 94.8 108.8 1.3 0.2 3.3 13.0 1.9 0.0 1.4 22.2 18.3 3.0 0.0 0.3 2.1 1.6 1.8 4.7 0.0 76.8 0.0 9.5 1.6 33.8 52.6 1.2 6.1 23.5 11.7 19.8 51.9 10.1 0.0 0.6 3.7 0.0 1.4 3.8 1.8 3.4 1.1 0.0 23.3 36.1 RIMS4 "C20orf190, dJ781B1.3" ENSG00000101098 "Regulating synaptic membrane exocytosis 4" Q9H426 20 44751808-44810546 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.9" "Cell type enhanced" "Detected in some" "Granulosa cells: 110.3;Horizontal cells: 38.7;Inhibitory neurons: 14.4;Sertoli cells: 26.3" "Cancer enhanced" "Detected in many" "breast cancer: 6.6;glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 19.3;MCF7: 13.4;SCLC-21H: 39.9;SH-SY5Y: 20.4;SiHa: 14.0;U-2 OS: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060928 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA060928: AB_2684387" "unprognostic (1.54e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (9.46e-2)" "unprognostic (2.97e-1)" "unprognostic (1.90e-2)" "unprognostic (4.63e-3)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (4.21e-3)" "unprognostic (1.70e-1)" "unprognostic (8.60e-3)" "unprognostic (3.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" 0.4 1.1 17.6 0.2 22.8 0.0 1.1 6.9 35.9 7.2 0.0 0.6 0.1 1.9 0.4 0.5 8.1 0.6 0.6 22.5 12.1 0.1 0.0 0.9 0.1 15.5 9.2 6.1 0.0 0.0 12.0 0.0 10.6 2.5 0.5 2.9 1.1 0.9 1.0 0.4 0.4 2.6 7.7 0.0 1.8 10.5 10.9 0.2 5.0 1.6 0.4 0.1 1.5 20.1 0.0 0.5 0.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.9 0.1 2.0 0.0 19.3 0.2 0.0 0.0 8.2 0.0 0.8 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 13.4 0.1 0.0 3.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 39.9 20.4 14.0 0.0 0.2 0.5 6.1 0.7 0.0 0.0 9.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 22.8 6.9 35.9 22.5 12.1 15.5 9.2 10.6 7.7 10.9 20.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.1 0.1 1.8 0.0 11.3 0.0 0.0 0.4 0.0 0.4 0.0 110.3 0.0 0.0 0.1 38.7 14.4 0.8 0.0 0.0 0.0 2.9 7.2 0.2 0.0 0.0 0.0 1.0 0.0 2.0 0.6 0.1 0.1 13.2 0.0 0.0 0.0 0.0 0.0 1.4 26.3 0.2 1.2 1.2 5.7 0.0 0.1 0.0 0.0 0.5 0.5 0.0 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 72.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 52.3;Endometrial ciliated cells: 76.5;Gastric mucus-secreting cells: 61.2;Glandular and luminal cells: 174.2;Squamous epithelial cells: 71.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.2;GAMG: 41.2;HaCaT: 47.5;hTCEpi: 31.4;RPTEC TERT1: 28.3;RT4: 30.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA030942 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.6 0.0 0.1 0.4 0.0 0.6 4.3 0.0 0.1 11.8 3.7 3.1 9.7 1.1 2.4 72.2 5.8 5.2 1.5 0.1 0.1 11.5 19.1 4.2 0.1 0.3 0.6 0.1 14.3 7.4 10.8 2.3 0.1 10.7 2.0 0.6 14.8 9.8 0.0 21.5 13.6 0.1 0.1 0.0 15.5 2.0 0.1 7.8 7.9 0.0 5.2 6.3 22.3 0.1 14.3 9.0 0.0 0.0 0.0 0.0 13.7 0.1 0.1 0.2 0.2 23.5 32.2 0.0 13.3 2.9 41.2 47.5 0.7 19.2 0.0 0.0 9.4 0.0 6.9 8.8 0.0 0.0 0.0 0.0 31.4 0.2 4.2 0.0 0.0 14.3 0.0 0.0 0.0 10.3 2.0 0.0 0.8 9.3 26.1 0.0 0.0 2.3 28.3 30.8 4.5 0.3 15.5 15.7 15.1 1.3 9.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 4.2 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.1 0.1 0.1 28.9 9.1 0.0 0.1 15.8 27.4 24.0 52.3 0.0 13.0 12.4 1.1 17.2 28.0 3.7 0.0 8.3 0.3 22.8 9.8 12.4 1.5 76.5 16.9 0.9 22.7 0.0 0.0 10.4 5.1 0.6 61.2 174.2 2.5 0.0 0.0 17.0 1.0 0.0 0.0 14.2 16.2 0.6 1.4 1.6 0.0 0.9 7.2 0.0 0.0 0.4 0.0 0.0 0.0 19.0 11.8 0.0 0.0 24.0 26.5 13.5 22.2 0.9 0.0 0.0 1.3 1.4 2.5 71.2 15.2 2.5 1.5 0.0 11.2 24.1 RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334930-5339876 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "prostate: 23.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Enteroendocrine cells: 4.8;Prostatic glandular cells: 10.6;Spermatocytes: 2.4;Spermatogonia: 3.1" "Cancer enriched" "Detected in some" 106 "prostate cancer: 67.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.2" "Secreted to blood" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 35: Glandular cells - Unknown function" "unprognostic (7.12e-6)" "unprognostic (2.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (4.08e-4)" "unprognostic (8.15e-2)" "unprognostic (2.89e-4)" "unprognostic (8.82e-3)" "unprognostic (3.23e-2)" "unprognostic (3.23e-2)" "unprognostic (1.53e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 0.2 0.0 0.5 1.0 0.8 0.2 2.8 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.6 1.6 0.7 0.2 0.1 4.8 1.7 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.4 10.6 0.0 0.4 1.0 0.8 0.0 0.2 0.1 2.4 3.1 0.0 0.1 1.1 1.6 0.1 0.2 0.3 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824095 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 8.9 5.0 7.7 4.6 7.3 7.5 7.5 16.1 9.0 7.1 6.1 9.0 3.4 12.2 4.1 5.7 7.9 4.7 24.9 7.7 6.8 5.6 5.1 5.9 5.0 6.3 6.8 5.5 5.3 6.8 5.3 3.5 6.6 7.3 3.7 13.9 5.9 5.2 32.1 6.1 5.5 11.1 5.7 5.0 5.8 3.9 7.5 5.0 6.1 25.3 4.7 7.9 5.6 7.1 11.0 4.5 5.4 3.9 9.6 12.5 4.2 8.1 15.1 5.9 7.1 4.9 3.8 7.7 9.0 11.7 5.7 7.5 6.0 5.5 6.3 7.7 3.9 6.1 5.9 4.6 6.1 9.7 13.7 7.3 4.8 6.0 7.1 6.7 7.7 5.9 6.1 12.2 10.8 8.3 7.1 6.0 6.8 7.0 9.4 6.7 5.4 6.4 11.6 3.6 5.3 7.4 6.6 8.0 6.3 6.6 8.9 9.1 9.4 8.4 6.6 5.1 8.7 10.2 10.3 8.0 4.2 6.4 5.4 6.4 1.0 1.6 1.4 0.8 1.2 1.5 1.0 1.4 0.8 1.2 1.0 1.4 0.7 1.6 0.8 1.1 1.0 0.7 7.7 7.3 16.1 9.0 7.7 6.8 6.3 6.8 6.6 5.7 7.5 7.1 168.4 16.0 29.2 61.7 43.5 20.6 32.6 24.4 23.9 101.3 35.9 29.1 152.5 38.6 27.0 18.4 114.7 26.8 155.6 13.2 33.2 44.8 68.5 52.9 45.4 72.3 27.1 60.6 91.2 80.3 28.7 60.8 28.1 55.8 31.7 39.1 71.7 33.1 37.2 82.4 77.6 23.5 28.5 41.5 36.2 25.3 39.4 38.9 39.2 84.3 71.0 64.4 90.6 81.4 83.9 52.4 18.8 80.9 90.5 76.0 22.5 46.6 29.6 111.1 59.2 60.2 53.5 76.5 63.7 23.7 18.0 19.8 75.7 65.2 23.6 40.2 RNF165 "Ark2C, ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;retina: 18.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.0;Cone photoreceptor cells: 100.1;Excitatory neurons: 47.4;Horizontal cells: 80.8;Inhibitory neurons: 34.4;NK-cells: 41.2;Oligodendrocyte precursor cells: 35.7;Rod photoreceptor cells: 49.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 10.1;HaCaT: 7.3;HeLa: 7.5;RPMI-8226: 6.4;SCLC-21H: 13.9;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA041615: AB_2677582, HPA047798: AB_2680158" "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 0.6 0.5 3.1 0.3 3.7 0.3 0.7 7.6 6.4 0.6 0.0 0.4 0.0 0.2 1.9 1.2 1.2 0.3 1.0 4.7 0.2 1.6 5.2 0.3 0.2 0.0 0.3 0.0 0.3 2.4 4.1 0.2 0.0 2.2 0.1 18.2 0.8 1.3 1.5 1.2 0.3 0.1 0.1 2.0 0.2 0.5 1.3 0.9 4.0 0.8 0.4 0.3 0.5 1.9 1.6 0.1 10.1 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 7.3 0.5 1.0 0.0 0.0 1.1 0.1 7.5 0.0 0.0 3.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 2.3 0.0 0.2 0.0 0.0 2.6 0.9 1.7 0.4 1.3 2.7 0.6 6.4 0.7 2.2 13.9 13.2 2.0 0.0 0.0 0.9 0.3 0.5 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 3.1 3.7 7.6 6.4 4.7 0.2 0.0 0.3 0.0 0.1 1.3 1.9 9.1 3.2 1.7 1.6 0.3 2.7 9.5 12.9 28.5 44.0 2.9 7.2 8.4 1.5 2.8 0.0 100.1 0.2 10.0 0.2 3.9 0.0 3.8 1.5 9.3 5.0 0.0 0.0 47.4 0.0 0.3 2.4 0.0 0.6 0.0 0.0 1.8 8.9 0.1 80.8 34.4 0.0 2.0 1.9 1.3 5.1 2.5 0.4 1.8 1.9 0.3 5.0 41.2 35.7 1.8 0.1 0.0 4.1 0.4 5.0 0.1 0.1 0.6 49.1 0.0 4.5 0.7 0.4 0.9 3.7 2.0 0.3 3.2 3.2 0.0 2.4 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.4;kidney: 11.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 15.9;Club cells: 9.8;Endometrial ciliated cells: 13.4;Glandular and luminal cells: 20.5;Ionocytes: 22.4;Proximal tubular cells: 26.4;Respiratory ciliated cells: 13.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 18.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057675 Uncertain NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA057675: AB_2683499" "unprognostic (1.23e-2)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.95e-6)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.51e-4)" "unprognostic (5.50e-2)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (2.53e-3)" 0.1 0.1 0.3 0.4 0.2 0.0 1.0 0.2 0.4 1.5 0.2 0.5 0.4 1.2 16.4 4.9 1.3 5.7 0.1 0.2 0.1 11.5 0.2 0.3 0.0 0.2 0.2 0.3 0.3 0.1 2.0 0.0 0.2 1.0 0.4 1.2 6.8 0.3 0.0 0.4 0.3 0.0 0.3 0.1 3.4 5.0 0.4 0.0 0.4 0.0 0.1 0.3 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.2 0.1 0.2 0.2 0.2 0.3 0.4 0.3 0.3 0.0 0.0 0.3 0.5 0.0 0.4 15.9 0.0 0.6 3.8 2.9 0.4 5.7 9.8 5.5 0.0 0.0 0.2 0.9 1.9 0.2 0.2 13.4 1.1 0.5 8.4 0.0 0.0 0.9 0.1 0.2 4.6 20.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 22.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 2.2 0.7 0.4 0.0 0.5 0.2 26.4 13.0 3.3 0.0 0.4 0.6 3.3 0.7 1.4 0.0 0.0 0.3 0.1 1.5 1.0 RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781696 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.5;Late spermatids: 257.6;Spermatocytes: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA018955: AB_1858500, HPA021123: AB_1858501" "unprognostic (3.31e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.40e-2)" "prognostic favorable (6.24e-5)" "unprognostic (2.88e-2)" "unprognostic (9.01e-2)" "unprognostic (3.49e-1)" "unprognostic (1.73e-2)" "unprognostic (1.06e-2)" "unprognostic (3.69e-3)" 14.3 12.3 14.3 12.8 15.9 15.6 13.1 12.6 14.6 13.2 10.0 25.5 8.1 21.9 8.2 12.3 15.8 8.7 21.7 13.8 17.5 10.0 10.1 12.8 17.0 14.9 15.4 16.5 14.9 13.9 15.4 7.7 14.8 14.6 5.8 7.2 11.4 13.7 19.6 13.3 17.9 15.0 12.8 19.2 14.6 30.1 16.2 12.8 12.7 11.9 11.5 16.4 10.9 14.3 22.0 23.6 17.0 32.8 21.6 14.6 11.5 20.7 19.3 17.6 15.8 16.7 12.3 17.3 11.4 22.0 38.7 17.1 13.6 15.3 10.3 11.4 19.3 12.5 13.6 18.0 27.7 19.5 25.3 21.4 20.4 16.2 14.6 18.4 15.0 19.2 28.4 12.9 18.9 35.2 8.8 44.7 25.7 13.1 20.0 26.1 23.4 12.2 13.9 13.9 14.1 25.3 11.8 33.9 13.2 15.3 14.2 28.2 20.5 24.9 39.9 25.2 22.8 11.4 9.0 16.0 19.6 21.7 37.4 3.5 7.7 24.2 10.1 8.3 9.4 8.3 9.3 8.7 6.3 8.8 10.9 11.3 13.2 12.7 8.7 7.1 8.3 6.9 14.3 15.9 12.6 14.6 13.8 17.5 14.9 15.4 14.8 12.8 16.2 14.3 33.4 6.4 23.9 34.9 33.6 16.6 20.8 11.9 15.9 36.4 16.1 17.8 33.3 8.6 13.6 12.9 52.1 14.1 47.7 10.3 25.4 17.6 145.5 14.6 33.7 29.7 6.0 8.8 50.2 13.7 12.9 26.7 16.3 16.9 19.6 34.0 26.4 15.1 22.9 28.6 61.7 15.4 6.1 23.0 29.3 257.6 37.3 23.1 12.4 49.6 37.0 30.2 56.7 46.3 64.2 15.6 7.0 30.1 20.3 24.2 13.0 14.9 13.7 48.5 26.3 46.0 30.0 159.8 124.2 12.9 16.2 15.2 40.2 22.8 11.8 15.2 RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.9;Basal respiratory cells: 96.2;Club cells: 55.7;Prostatic glandular cells: 57.2;Urothelial cells: 233.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.5;U-266/84: 3.6" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" 1.1 0.8 0.0 0.0 0.1 0.0 8.6 0.1 0.3 16.8 0.0 0.6 0.2 0.6 0.0 24.5 1.4 0.1 0.3 0.1 0.1 0.4 0.2 1.9 0.0 0.2 0.0 1.3 1.7 0.1 1.4 0.0 0.2 7.2 0.0 0.5 15.8 0.1 0.4 63.3 0.5 0.0 0.0 0.2 8.3 1.6 0.1 0.0 0.4 0.0 0.4 3.9 21.6 0.1 1.2 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.2 1.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 0.9 0.3 0.2 0.0 0.4 0.0 0.5 0.0 4.5 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.8 3.6 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.3 3.2 2.7 0.0 0.0 17.8 79.9 96.2 42.1 0.5 23.7 28.6 0.3 7.2 55.7 0.0 0.0 0.0 0.8 1.8 0.0 6.4 0.6 3.6 2.4 1.1 0.0 0.0 0.0 3.3 0.0 1.2 17.3 20.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 14.2 0.0 2.1 0.0 1.2 0.4 3.6 0.0 0.6 0.0 0.0 0.0 0.0 24.2 2.2 1.2 0.0 57.2 0.1 0.0 13.0 0.4 0.0 0.0 3.0 0.1 0.4 11.3 23.9 0.7 0.6 0.0 0.9 233.1 ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 309.4;Inhibitory neurons: 1518.9;Oligodendrocyte precursor cells: 348.3;Oligodendrocytes: 479.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" 12.4 8.6 12.7 10.7 13.7 0.2 4.9 4.3 9.5 13.4 0.0 7.8 3.1 9.5 7.2 12.3 4.7 7.7 6.7 7.8 10.8 3.1 3.6 7.6 9.3 8.8 16.3 16.4 1.9 1.8 7.4 7.8 9.9 12.9 6.0 3.9 5.4 11.9 4.5 20.5 4.3 10.5 7.5 9.0 4.8 10.3 15.5 13.3 4.8 5.4 18.2 13.9 11.1 12.4 0.2 26.9 25.7 41.3 35.0 22.8 1.4 21.1 28.0 16.3 13.8 0.6 11.5 0.0 0.1 26.2 13.0 10.9 31.5 21.6 20.5 0.4 39.1 16.4 51.4 43.4 8.4 0.3 4.1 38.3 28.9 61.9 29.1 30.5 16.5 0.0 2.2 49.0 16.8 13.1 0.0 0.1 32.8 7.9 9.6 0.9 27.2 0.3 0.1 8.9 19.7 13.7 45.5 9.9 16.2 24.6 31.8 0.4 0.3 54.1 23.4 32.7 36.1 1.7 0.0 0.0 49.2 0.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 12.7 13.7 4.3 9.5 7.8 10.8 8.8 16.3 9.9 7.5 15.5 12.4 4.3 3.2 11.0 81.0 1.9 33.1 20.6 17.9 39.9 11.7 4.1 3.6 3.6 0.0 9.0 7.3 4.2 9.7 0.0 0.1 0.0 0.5 23.9 1.6 23.2 14.3 1.2 4.0 309.4 0.2 8.3 34.6 3.6 2.3 1.3 5.1 16.1 0.3 1.5 1.7 1518.9 1.4 22.4 2.6 10.0 65.9 19.9 1.5 14.2 51.5 1.9 5.7 0.0 348.3 479.3 0.2 5.1 24.5 1.3 20.5 4.9 0.4 2.9 1.0 13.1 24.7 16.8 2.7 7.0 30.3 33.8 5.6 0.9 71.1 2.6 52.7 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 RPS4Y2 RPS4Y2P ENSG00000280969 "Ribosomal protein S4 Y-linked 2" Q8TD47 Y 20756108-20781032 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 1.9;testis: 1.1" "Cell type enhanced" "Detected in some" "B-cells: 3.5;Basal keratinocytes: 3.2;Basal prostatic cells: 3.5;Langerhans cells: 3.4;Prostatic glandular cells: 2.1;Spermatogonia: 2.6;Suprabasal keratinocytes: 5.8" "Cancer enriched" "Detected in single" 9 "prostate cancer: 1.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.4" "Cell line enriched" "Detected in single" 5 "U-266/84: 2.0" HPA000857 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "HPA000857: AB_1079849" "unprognostic (1.50e-2)" "unprognostic (3.63e-1)" "unprognostic (6.39e-6)" "unprognostic (5.92e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.2 0.1 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.2 3.5 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.1 2.6 0.0 5.8 0.3 0.4 0.0 0.0 1.3 RPS6KL1 "MGC11287, RSKL2" ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903951-74923302 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Cone photoreceptor cells: 83.4;Horizontal cells: 40.4;Rod photoreceptor cells: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 17.5;SCLC-21H: 25.1;SK-BR-3: 19.7;U-266/70: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA027451: AB_10599304, HPA027794: AB_10602098" "unprognostic (2.71e-2)" "unprognostic (9.33e-3)" "unprognostic (3.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.44e-2)" "unprognostic (7.49e-4)" "unprognostic (2.06e-1)" "unprognostic (1.54e-1)" "unprognostic (4.09e-3)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.03e-2)" "unprognostic (7.52e-2)" 3.7 4.5 22.4 1.1 23.1 3.0 4.1 21.6 29.4 1.9 17.6 6.7 2.2 4.1 4.8 2.9 2.5 1.8 13.7 23.4 21.2 4.8 4.2 2.5 1.4 20.8 21.3 0.9 7.9 1.3 18.8 0.5 20.5 3.8 3.2 20.6 3.1 3.0 19.1 2.3 3.1 4.0 19.3 3.2 2.5 13.9 21.7 0.6 4.3 4.2 1.1 3.4 1.7 22.9 3.3 0.5 1.3 4.4 0.2 0.0 6.3 0.7 0.2 1.6 0.4 5.8 2.4 0.1 4.5 1.1 0.7 0.4 1.9 0.1 1.6 0.0 0.6 2.7 1.2 4.8 5.7 3.2 17.5 0.5 3.5 2.3 0.0 0.0 7.9 0.0 3.2 0.9 0.1 10.7 0.1 1.1 1.3 1.0 5.1 2.0 0.1 9.7 2.3 0.0 25.1 3.8 0.4 19.7 3.4 2.7 1.5 2.1 5.8 0.1 0.2 4.0 0.0 13.8 8.1 6.9 1.8 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.1 0.0 0.0 0.3 0.7 0.8 0.0 0.0 0.0 2.3 0.0 0.1 22.4 23.1 21.6 29.4 23.4 21.2 20.8 21.3 20.5 19.3 21.7 22.9 2.6 0.0 0.0 10.4 0.9 0.8 2.7 1.2 0.6 72.3 4.3 3.9 6.1 0.0 0.8 3.7 83.4 1.7 2.0 2.4 1.9 1.3 7.7 0.8 0.6 2.6 6.7 5.2 24.5 6.2 1.7 1.0 0.5 0.7 0.0 0.7 1.1 2.6 3.7 40.4 19.7 2.1 4.1 0.3 1.3 7.4 2.1 1.0 3.6 3.7 0.0 5.0 3.1 15.6 15.1 3.8 1.6 2.6 0.5 2.1 1.5 1.9 4.5 73.6 6.6 3.8 3.1 27.0 22.9 1.2 1.3 1.4 1.0 1.5 3.1 1.6 RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 46.0;Excitatory neurons: 70.1;Inhibitory neurons: 66.3;Microglial cells: 32.8;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Enhanced Vesicles,Lysosomes NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Lysosomes" "CAB013514: AB_2533523, HPA064306: AB_2685240" "unprognostic (5.09e-3)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (9.75e-2)" "unprognostic (3.34e-3)" "unprognostic (1.17e-2)" "unprognostic (9.63e-2)" "unprognostic (8.80e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-2)" 5.9 4.6 3.5 4.4 3.3 4.1 3.6 2.0 4.4 4.3 0.1 5.7 4.8 5.6 1.8 4.5 4.5 2.9 6.1 3.8 2.6 3.1 3.4 4.2 3.3 3.3 2.8 4.8 5.5 5.3 4.0 3.6 3.3 4.5 2.4 2.6 4.6 5.0 14.1 5.1 4.5 4.6 2.0 3.8 4.4 4.0 3.5 4.4 3.6 7.0 2.7 5.4 3.6 3.2 16.2 34.7 6.8 12.9 9.5 7.0 15.5 12.7 9.5 17.9 12.4 21.5 13.8 13.3 10.1 12.9 13.8 11.6 10.5 15.7 8.9 5.6 19.6 20.8 16.8 21.2 8.9 19.8 15.3 12.3 9.9 17.3 9.1 5.9 16.6 15.7 24.9 4.6 8.6 8.8 12.4 7.8 7.4 9.2 24.0 10.2 12.9 11.2 4.6 17.8 13.4 17.4 14.4 22.9 14.9 6.6 16.3 14.5 9.6 37.1 17.8 11.6 15.7 8.9 3.9 12.6 22.4 10.1 23.6 0.0 0.1 0.0 0.5 0.3 0.3 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.0 0.1 0.2 0.0 1.0 0.4 3.5 3.3 2.0 4.4 3.8 2.6 3.3 2.8 3.3 2.0 3.5 3.2 4.3 0.0 3.9 46.0 8.5 3.2 3.0 2.4 4.6 6.8 4.2 3.3 4.5 5.7 1.6 5.5 4.2 4.4 7.2 3.8 1.9 3.6 6.7 3.9 5.4 4.3 6.0 4.8 70.1 3.8 5.9 4.8 8.2 4.9 2.5 7.5 2.2 7.5 4.7 11.8 66.3 3.1 6.1 5.7 3.2 10.9 3.1 6.7 1.8 32.8 1.7 4.3 2.1 50.8 66.2 4.7 3.5 5.3 9.4 4.5 4.6 2.7 2.0 7.0 0.0 5.5 4.1 4.5 3.5 5.1 3.0 4.4 9.3 6.0 5.6 3.8 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RTP5 "C2orf85, CXXC11, FLJ33590, Z3CXXC5" ENSG00000188011 "Receptor transporter protein 5 (putative)" Q14D33 2 241869600-241873823 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "brain: 32.9" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Inhibitory neurons: 4.1;Late spermatids: 2.8;Oligodendrocyte precursor cells: 17.6" "Cancer enriched" "Detected in single" 10 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "MOLT-4: 1.3;SCLC-21H: 2.6" "Low region specificity" "Detected in all" HPA050902 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" "HPA050902: AB_2681268" "unprognostic (3.26e-2)" "unprognostic (5.38e-4)" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "unprognostic (9.40e-4)" "unprognostic (8.68e-3)" "unprognostic (2.04e-1)" "unprognostic (6.34e-4)" "unprognostic (3.30e-1)" "unprognostic (9.01e-3)" "unprognostic (3.91e-1)" "unprognostic (9.08e-8)" "unprognostic (1.81e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.72e-2)" 0.3 0.0 25.8 0.1 10.0 0.3 0.1 0.0 18.9 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 29.7 32.9 0.1 0.1 0.5 0.5 5.1 17.3 0.0 0.0 0.0 0.1 0.0 16.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 6.2 1.4 0.3 0.4 25.4 0.3 0.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 10.0 0.0 18.9 29.7 32.9 5.1 17.3 16.3 6.2 25.4 1.3 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.8 0.0 0.4 0.0 1.0 0.0 0.0 0.0 17.6 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 RUNDC3B "RPIB9, RPIP9" ENSG00000105784 "RUN domain containing 3B" Q96NL0 7 87627548-87832296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.3;brain: 6.3;liver: 5.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 167.5;Inhibitory neurons: 170.9;Microglial cells: 108.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.2;HEK 293: 1.0;SCLC-21H: 2.7;SH-SY5Y: 1.2;U-138 MG: 1.0;U-266/70: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056968, HPA057155, HPA075760" Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA056968: AB_2683292, HPA057155: AB_2683353, HPA075760: " "unprognostic (2.49e-1)" "unprognostic (1.99e-1)" "unprognostic (2.12e-1)" "unprognostic (1.83e-1)" "unprognostic (2.20e-2)" "unprognostic (1.77e-3)" "unprognostic (1.19e-2)" "unprognostic (4.16e-2)" "unprognostic (2.56e-1)" "unprognostic (1.19e-1)" "unprognostic (9.42e-5)" "unprognostic (4.44e-1)" "prognostic favorable (2.62e-6)" "unprognostic (1.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.32e-1)" "unprognostic (9.55e-2)" 0.4 7.3 3.1 0.1 2.9 0.0 0.6 6.3 3.9 1.4 0.0 1.3 2.8 1.9 0.6 0.5 1.0 0.9 0.7 2.0 3.7 1.9 5.6 0.4 0.2 2.5 1.5 1.2 0.1 0.3 0.2 0.0 2.2 0.6 1.5 1.7 0.3 0.4 0.1 0.5 2.5 2.1 0.8 0.1 0.1 1.9 4.0 0.1 0.2 0.1 0.2 0.5 0.3 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.0 0.0 0.5 0.4 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.7 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.9 6.3 3.9 2.0 3.7 2.5 1.5 2.2 0.8 4.0 1.3 15.3 0.0 0.0 5.5 0.6 4.8 0.1 0.1 2.2 7.9 1.0 1.1 2.5 7.2 0.1 0.0 6.2 0.5 0.9 12.2 1.9 1.1 4.6 5.6 0.5 30.8 0.0 2.7 167.5 0.2 0.8 1.1 0.0 2.0 0.0 0.7 1.4 18.9 0.1 11.8 170.9 2.9 0.0 0.0 2.3 1.7 4.1 0.6 3.6 108.7 0.2 0.7 4.1 15.1 5.7 0.6 6.5 1.5 0.1 0.2 18.2 11.6 0.2 8.0 0.0 0.3 2.0 21.2 18.8 0.4 3.0 1.2 0.8 1.6 4.2 0.1 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193357-83198935 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 52.3;Spermatocytes: 65.2" "Cancer enhanced" "Detected in all" "prostate cancer: 11.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030105: AB_10599826, HPA030106: AB_10600896, HPA030107: AB_10601009" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "prognostic favorable (3.82e-5)" "prognostic favorable (1.38e-4)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-3)" "unprognostic (2.59e-2)" 2.9 6.9 7.1 2.1 7.0 0.5 3.2 6.1 8.1 3.4 6.3 2.9 2.5 3.3 9.4 1.7 3.8 4.6 4.4 6.9 7.9 4.5 5.9 2.8 2.5 5.6 6.0 4.0 9.6 4.0 5.6 2.5 5.9 11.5 2.5 4.7 6.0 4.7 2.3 1.9 2.7 3.2 5.7 2.9 3.9 8.9 8.4 1.8 6.2 4.0 2.6 2.6 1.8 6.1 2.1 1.9 4.4 8.3 5.2 3.7 3.0 4.8 10.1 3.5 4.2 2.8 1.1 1.6 3.8 5.8 8.0 2.1 3.7 2.8 5.4 2.0 3.8 1.9 3.0 6.2 8.0 0.5 1.5 4.9 4.6 4.4 9.2 11.5 6.6 4.5 3.1 2.8 4.3 3.1 0.7 1.5 1.5 1.9 1.9 2.4 9.1 1.0 7.4 2.4 1.5 5.3 2.9 4.5 4.4 6.3 2.8 2.9 7.1 2.4 1.5 3.5 2.1 6.2 2.7 0.9 2.8 0.8 2.9 0.3 0.9 0.0 1.2 0.8 1.8 1.9 1.7 1.7 1.0 1.0 2.2 2.1 0.3 0.4 2.2 3.5 2.2 1.0 7.1 7.0 6.1 8.1 6.9 7.9 5.6 6.0 5.9 5.7 8.4 6.1 2.4 0.0 6.7 9.8 4.2 3.7 3.6 5.3 3.4 5.6 3.7 3.2 5.4 2.8 3.3 1.8 0.0 7.7 3.9 2.4 5.9 8.9 52.3 4.8 4.5 3.5 5.4 0.4 10.8 9.1 3.3 6.5 3.6 4.0 0.0 7.0 5.0 6.8 5.0 1.7 11.2 6.1 8.2 1.6 2.5 14.8 9.0 2.2 8.8 3.7 3.8 11.0 0.0 13.6 4.5 5.8 2.5 6.0 11.2 8.7 4.1 13.3 4.9 5.0 6.6 7.0 5.2 65.2 10.5 1.2 2.4 5.7 2.9 6.3 3.4 2.8 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 995.4;Pancreatic endocrine cells: 1307.3;Prostatic glandular cells: 1141.1;Squamous epithelial cells: 1028.7;Suprabasal keratinocytes: 908.8;Theca cells: 1528.4;Urothelial cells: 1522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1369.9;SK-BR-3: 1618.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" 166.8 79.1 81.3 61.9 79.8 0.8 159.7 78.6 98.0 333.0 70.8 139.7 121.5 78.4 19.8 2477.7 68.2 81.6 122.3 79.8 80.1 219.0 209.9 161.3 28.4 104.2 80.9 83.4 41.0 76.6 42.0 71.8 84.9 77.8 105.0 7.0 438.1 38.1 51.7 474.9 109.8 79.0 84.8 118.5 100.4 60.3 103.4 25.0 72.4 52.1 205.0 163.2 713.3 84.6 670.4 318.1 16.0 36.7 102.5 386.8 42.8 367.9 341.4 302.7 265.2 315.4 366.1 0.3 577.5 553.0 69.0 479.6 1.1 839.2 175.3 1.9 0.6 0.4 260.5 90.8 117.5 0.2 0.9 182.7 787.6 731.6 567.9 390.9 1369.9 0.0 8.5 0.8 677.3 918.7 0.9 1.4 69.0 1171.0 887.9 0.9 187.4 1.8 1150.3 236.1 0.8 1.9 267.6 1618.0 55.7 140.5 504.7 3.5 743.9 178.2 289.5 171.5 848.6 0.5 3.5 2.4 525.0 0.9 122.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 81.3 79.8 78.6 98.0 79.8 80.1 104.2 80.9 84.9 84.8 103.4 84.6 275.6 38.5 25.5 10.4 6.8 633.9 995.4 531.6 157.6 0.5 225.4 191.3 33.0 124.4 290.6 108.5 2.1 20.3 4.4 500.7 72.4 610.9 4.9 50.9 172.5 293.5 139.0 16.0 0.0 193.9 8.7 112.2 96.8 128.5 19.1 154.1 365.9 132.7 5.0 0.0 0.1 286.4 164.8 15.7 95.4 17.4 67.1 7.4 112.1 5.6 7.2 72.5 0.0 7.5 0.7 1307.3 610.0 61.3 5.6 1141.1 353.3 169.7 48.6 2.1 6.6 70.9 91.2 8.0 1.3 1028.7 908.8 8.2 12.9 1528.4 320.2 1522.5 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 92.9;Early spermatids: 92.3;Late spermatids: 184.9;Syncytiotrophoblasts: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.0" "Group enriched" "Detected in many" 8 "granulocytes: 45.0;T-cells: 12.4" "Cell line enhanced" "Detected in many" "BEWO: 29.4;Daudi: 54.1;U-266/70: 38.9;U-698: 57.3;WM-115: 38.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" 7.7 2.5 1.9 6.4 1.8 1.2 5.5 1.7 1.8 10.4 1.9 4.8 1.8 8.3 2.7 3.3 8.4 6.2 6.6 1.6 2.0 3.1 5.6 13.7 10.9 2.8 1.9 5.6 2.9 2.5 3.0 18.5 2.2 6.9 2.4 1.2 4.1 2.3 0.8 5.4 4.8 4.2 2.0 1.9 4.3 13.2 2.1 1.4 3.4 1.3 10.9 8.3 7.0 2.9 3.0 0.4 3.4 6.9 18.2 22.2 29.4 4.4 8.9 1.9 4.1 1.9 1.7 54.1 5.1 8.2 2.3 1.7 1.2 2.1 1.3 5.5 2.7 1.2 1.2 1.3 6.1 1.4 1.1 12.2 1.1 3.8 1.3 5.3 0.2 2.6 1.3 11.1 1.3 2.5 0.6 2.5 3.4 0.9 1.7 3.8 1.4 2.0 1.6 2.5 2.4 4.7 2.5 1.5 3.8 2.6 1.2 1.3 0.4 6.9 2.2 15.9 1.3 38.9 19.6 57.3 2.6 2.7 38.6 45.0 2.8 0.6 7.2 2.4 8.9 0.3 9.2 7.0 2.6 0.5 3.7 3.8 0.7 3.6 1.0 0.4 12.4 2.0 1.9 1.8 1.7 1.8 1.6 2.0 2.8 1.9 2.2 2.0 2.1 2.9 2.0 0.0 1.1 0.3 2.0 0.0 4.6 0.0 1.2 0.6 8.3 4.6 0.6 2.8 0.6 1.8 2.1 92.9 5.4 0.0 0.0 3.6 92.3 8.6 21.5 2.0 2.4 0.0 0.3 3.3 18.1 17.7 0.0 18.1 0.0 2.0 3.9 7.6 13.2 0.0 0.9 0.5 0.0 3.1 0.0 184.9 22.1 7.2 0.0 0.0 4.0 7.1 3.1 6.6 0.5 2.7 0.3 13.2 2.6 4.9 0.0 0.9 0.0 0.5 13.1 2.0 4.6 1.5 1.2 2.0 0.0 68.4 4.2 1.1 0.2 4.1 S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.6;lymphoid tissue: 61.1" "Cell type enhanced" "Detected in some" "B-cells: 62.3;dendritic cells: 76.7;monocytes: 33.7;NK-cells: 140.1;T-cells: 64.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 24.0;HL-60: 32.2;NB-4: 31.7;REH: 89.2;U-937: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" 4.6 1.0 0.3 10.7 0.2 19.6 2.8 0.1 2.4 1.0 0.2 2.3 1.1 0.9 0.0 2.3 2.3 1.0 1.6 0.2 0.1 1.7 1.6 11.9 16.5 0.3 0.1 0.3 0.7 0.1 0.3 1.4 0.6 1.3 0.2 0.0 1.2 0.1 0.6 0.8 13.6 0.5 0.2 61.1 4.9 0.2 0.5 4.8 2.9 0.7 4.8 2.8 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.9 0.3 0.0 0.0 0.3 0.0 0.1 0.0 24.0 0.0 10.2 0.2 0.0 0.0 32.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 31.7 0.0 0.3 0.0 89.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 3.5 0.0 30.4 0.0 53.2 28.3 81.0 31.1 32.5 27.2 32.3 37.9 29.9 20.4 39.3 31.6 30.2 120.8 16.3 44.7 18.1 67.6 21.6 0.3 0.2 0.1 2.4 0.2 0.1 0.3 0.1 0.6 0.2 0.5 0.1 6.3 3.2 4.6 0.0 62.3 1.3 0.2 0.8 0.0 0.0 0.4 0.3 0.4 1.5 1.9 1.8 0.0 0.2 76.7 0.2 0.0 0.1 0.1 0.4 0.1 4.1 0.0 17.0 0.0 0.2 0.2 0.5 3.1 0.3 5.7 0.0 6.8 0.8 25.2 0.0 0.0 0.0 0.0 27.6 8.3 0.0 0.0 27.8 1.8 0.0 33.7 0.0 140.1 0.0 0.0 0.1 0.0 0.0 27.7 0.3 0.0 0.3 2.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 1.4 0.0 64.0 0.0 0.0 0.6 SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23328826-23433740 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5;Excitatory neurons: 86.3;Inhibitory neurons: 108.2;Oligodendrocyte precursor cells: 76.4;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" 4.8 4.4 4.7 4.0 10.0 5.6 4.3 7.2 16.1 4.8 0.0 8.0 0.9 6.2 2.7 3.7 5.8 2.2 8.7 7.6 3.0 3.2 2.2 4.8 4.3 8.4 5.2 4.7 4.8 15.2 6.8 1.3 9.4 7.6 1.5 4.6 6.6 2.3 14.0 2.4 5.0 4.9 2.0 8.5 5.1 6.8 10.3 4.2 2.6 13.1 3.6 9.9 4.4 11.4 8.1 10.5 21.3 6.5 6.5 24.3 3.1 18.1 23.2 6.9 5.7 5.0 4.2 5.5 7.4 38.8 9.0 1.6 30.7 10.8 22.5 12.9 12.6 20.7 8.1 7.4 4.8 38.1 7.9 7.8 2.5 44.3 21.2 9.7 23.1 17.0 12.1 2.6 31.6 3.8 13.6 14.6 17.5 2.8 8.2 16.0 38.7 16.7 12.0 0.9 15.4 14.8 10.0 3.6 7.8 9.7 1.9 10.0 49.8 21.1 17.4 11.5 34.6 5.0 5.7 13.3 10.1 13.2 18.7 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.4 0.7 0.2 0.3 0.0 0.3 0.0 0.3 0.7 0.1 4.7 10.0 7.2 16.1 7.6 3.0 8.4 5.2 9.4 2.0 10.3 11.4 10.3 0.0 1.3 70.5 14.5 6.1 5.4 2.0 6.8 16.5 8.2 8.0 21.3 1.5 1.4 1.8 0.0 0.4 15.3 0.2 0.0 9.0 13.1 5.6 28.1 11.6 1.2 9.7 86.3 10.4 1.5 17.4 3.1 3.3 2.5 18.8 3.6 0.7 3.4 25.2 108.2 0.4 2.0 4.9 19.4 11.6 4.1 8.1 8.8 19.7 3.9 13.6 6.2 76.4 111.0 16.7 0.2 5.3 12.9 8.1 0.0 1.3 1.2 5.3 13.1 45.6 20.9 20.5 9.5 5.3 5.1 0.0 18.1 20.0 0.8 2.9 SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA 37000 "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.27e-1)" 43.9 34.7 33.1 18.7 33.9 21.5 38.9 30.2 39.9 47.8 29.7 115.7 9.9 58.5 4.9 53.0 44.5 14.7 44.3 34.2 34.3 29.4 32.4 39.5 23.1 33.4 33.5 36.4 29.3 22.1 27.2 21.6 33.4 38.5 15.8 11.0 31.0 22.3 53.6 41.3 43.2 27.6 30.5 51.8 59.1 76.6 35.6 36.5 50.8 17.7 24.9 68.1 42.3 34.4 126.7 71.6 189.2 81.8 57.9 68.8 51.3 180.7 130.3 154.7 192.7 76.0 61.6 131.4 72.6 112.0 89.6 49.4 179.6 93.2 141.0 138.4 172.0 117.4 45.2 62.7 68.4 142.3 81.7 64.0 42.2 75.4 72.0 58.9 142.2 141.3 138.7 51.3 135.9 68.0 127.1 396.8 87.3 116.0 68.5 171.7 110.2 47.9 56.2 77.1 59.9 79.3 126.8 87.9 79.3 84.3 70.8 75.9 72.7 71.0 103.8 47.0 161.9 97.0 352.1 206.5 44.7 108.7 98.5 55.3 37.6 21.7 41.6 34.7 45.2 37.2 50.4 43.2 45.2 29.6 69.9 54.6 18.9 63.8 23.6 30.1 69.4 65.3 33.1 33.9 30.2 39.9 34.2 34.3 33.4 33.5 33.4 30.5 35.6 34.4 29.2 9.6 18.7 11.4 24.1 25.6 32.6 33.2 16.5 20.1 19.2 16.3 21.9 15.7 18.6 12.9 6.2 77.7 20.5 18.5 11.7 41.6 13.1 13.3 34.4 39.4 19.2 36.6 20.9 34.9 107.2 30.8 17.3 22.0 15.2 40.2 22.1 21.0 57.6 20.2 21.8 25.2 42.7 17.2 25.0 19.1 15.5 19.2 46.2 10.3 48.5 25.8 41.2 10.6 16.3 38.1 20.1 18.8 26.3 32.6 11.4 15.6 7.2 16.6 52.6 16.5 39.0 151.3 113.7 22.4 24.6 57.5 33.5 35.4 32.5 30.5 SALL3 ZNF796 ENSG00000256463 "Spalt like transcription factor 3" Q9BXA9 18 78980275-79002677 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;prostate: 6.0;vagina: 8.0" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Bipolar cells: 14.7;Cone photoreceptor cells: 47.9;Horizontal cells: 25.2;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in some" 6 "glioma: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;HEK 293: 2.7;NTERA-2: 9.5;SuSa: 1.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.5" "Low region specificity" "Detected in many" HPA016656 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "HPA016656: AB_1856546" "unprognostic (3.96e-2)" "unprognostic (3.41e-3)" "unprognostic (8.16e-2)" "unprognostic (1.87e-2)" "unprognostic (2.37e-1)" "unprognostic (4.23e-1)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (5.86e-3)" 0.0 0.0 5.7 0.0 6.2 0.0 0.0 5.8 5.7 1.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 5.2 8.2 3.3 0.0 0.0 0.0 9.0 6.5 0.0 0.0 0.0 1.2 0.0 7.2 6.0 0.0 1.8 0.7 0.1 0.0 0.0 0.0 0.0 9.4 0.0 0.0 1.3 6.3 0.0 0.0 0.0 0.0 0.4 8.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 6.2 5.8 5.7 5.2 8.2 9.0 6.5 7.2 9.4 6.3 7.5 0.2 0.0 0.0 25.5 0.0 0.0 7.4 0.0 0.0 14.7 0.0 0.1 1.8 0.0 0.0 1.8 47.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 25.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 4.8 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 1.8 6.6 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.3 SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "dendritic cells: 157.0;NK-cells: 271.9;Plasma cells: 43.7;T-cells: 84.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.8;HDLM-2: 3.4;hTEC/SVTERT24-B: 2.2;hTERT-RPE1: 1.9;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" 1.1 2.3 1.4 4.0 2.0 4.2 0.9 0.6 1.6 2.9 0.6 1.2 0.7 4.4 1.9 0.7 1.5 2.3 0.5 2.9 1.2 1.1 1.7 3.3 10.4 0.8 2.0 1.8 1.2 0.1 4.8 0.7 0.9 0.7 2.3 1.4 0.7 0.4 0.8 0.5 1.4 1.7 0.4 9.3 1.6 3.2 1.9 6.3 0.8 0.7 4.2 1.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.3 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.3 0.0 2.2 0.1 1.9 0.2 0.4 0.1 0.0 0.2 0.0 0.1 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.5 113.8 0.4 90.0 2.5 39.8 102.1 0.6 0.3 28.8 68.9 2.3 128.4 0.6 0.6 41.7 41.4 1.4 2.0 0.6 1.6 2.9 1.2 0.8 2.0 0.9 0.4 1.9 0.4 1.1 0.0 2.3 1.3 2.3 0.4 0.0 0.0 0.6 3.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 157.0 1.6 0.0 0.2 25.4 1.0 2.1 0.8 3.6 6.6 12.1 0.0 0.0 0.7 0.0 0.5 1.3 14.8 2.9 0.4 0.0 0.0 5.7 0.3 0.0 3.4 1.4 6.7 0.6 1.8 5.4 12.2 2.3 0.0 271.9 1.5 0.6 0.0 1.5 1.9 43.7 0.0 0.1 0.6 0.7 0.4 0.0 0.3 1.4 2.3 1.6 0.2 0.4 0.0 84.3 2.0 0.5 0.1 SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.7;Distal enterocytes: 104.6;NK-cells: 109.2;Paneth cells: 171.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 28.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 66.7;GAMG: 66.0" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA021318: AB_2183383, HPA021319: AB_1856554" "unprognostic (3.66e-2)" "unprognostic (5.35e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (8.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (4.76e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (8.31e-5)" "unprognostic (6.00e-2)" "prognostic unfavorable (8.40e-7)" "unprognostic (5.91e-2)" "unprognostic (1.37e-2)" "unprognostic (2.18e-2)" "unprognostic (3.64e-1)" 4.1 3.6 1.1 13.2 1.0 9.9 3.5 1.1 1.0 8.0 1.4 11.0 7.5 3.5 2.9 39.1 3.0 7.2 2.4 1.1 1.6 3.2 3.7 7.7 15.8 2.8 1.5 5.8 1.6 1.0 0.9 7.0 2.0 2.0 11.3 0.3 4.3 2.4 0.6 1.9 7.7 4.0 2.9 17.7 10.7 1.0 2.1 20.7 2.0 2.3 15.9 7.0 8.3 2.5 28.5 3.6 1.0 0.2 12.0 15.2 0.3 10.9 45.2 51.0 66.7 0.2 30.9 11.9 16.8 27.1 66.0 32.6 0.1 10.0 17.1 40.5 1.3 17.3 18.0 0.0 5.4 19.5 23.1 6.8 14.1 16.8 4.6 2.8 7.7 13.1 1.2 28.6 10.9 0.1 29.2 15.9 0.1 0.0 7.9 9.5 9.2 13.5 0.3 3.6 4.4 0.4 8.4 3.3 9.1 0.1 1.0 9.5 33.8 11.8 4.2 36.0 6.0 16.9 3.4 10.8 12.3 11.2 12.1 21.8 4.2 15.7 8.3 8.1 7.7 5.6 6.4 7.3 3.6 5.9 6.7 6.1 17.8 8.8 12.8 2.5 8.8 3.2 1.1 1.0 1.1 1.0 1.1 1.6 2.8 1.5 2.0 2.9 2.1 2.5 43.9 9.6 3.7 0.7 53.4 2.3 8.2 40.2 4.0 1.4 4.4 5.1 1.2 5.7 33.7 14.7 0.0 1.9 92.7 104.6 0.0 23.5 0.1 21.1 18.5 29.0 3.0 19.4 0.4 12.3 7.1 14.6 37.8 7.0 43.6 21.8 12.1 1.2 11.5 6.7 1.5 34.9 20.3 29.9 9.6 0.7 15.2 32.7 3.6 21.5 41.6 2.2 109.2 2.0 2.4 50.4 171.0 12.4 35.9 7.0 12.6 2.3 37.5 0.1 13.1 14.4 12.6 0.2 0.0 21.1 1.8 0.4 69.4 25.4 5.6 34.3 SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1;esophagus: 8.5;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 10.8;Oligodendrocyte precursor cells: 29.7;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 122.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA044154: AB_10959464" "unprognostic (3.68e-2)" "unprognostic (9.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-8)" "prognostic unfavorable (5.88e-4)" "unprognostic (8.33e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-7)" "unprognostic (4.37e-3)" "unprognostic (4.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" 0.5 0.3 6.9 2.4 5.1 2.0 1.3 4.7 5.4 1.2 1.3 3.7 4.3 0.4 0.0 8.5 0.3 0.2 0.2 5.4 4.5 1.2 0.2 0.5 2.7 7.1 6.8 0.1 0.4 0.0 0.5 0.9 5.7 3.1 1.8 0.1 4.1 0.1 0.1 6.2 4.3 0.4 5.0 2.2 2.4 0.5 6.8 2.3 0.3 0.0 2.5 0.4 2.3 7.0 52.1 27.5 10.7 32.0 0.3 0.7 57.1 8.4 5.7 8.8 4.1 52.5 23.2 53.8 26.5 4.1 8.2 72.3 33.6 9.7 2.0 37.4 38.9 23.6 32.7 59.6 0.2 27.0 39.2 0.1 1.5 3.0 5.8 2.3 14.4 27.1 33.1 23.7 2.6 122.1 7.8 72.7 19.9 119.2 61.9 82.9 40.7 60.1 10.9 14.8 55.2 32.7 32.2 89.1 12.2 2.4 71.9 51.1 9.4 7.9 26.6 24.0 41.9 8.2 25.5 26.3 18.4 31.8 25.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.9 5.1 4.7 5.4 5.4 4.5 7.1 6.8 5.7 5.0 6.8 7.0 0.5 0.0 0.0 0.7 1.9 4.2 0.7 0.5 0.6 0.2 5.0 5.2 1.3 0.0 1.1 0.0 0.0 2.8 1.6 5.4 1.9 0.3 0.0 1.6 0.8 0.9 0.0 3.6 0.2 0.0 3.5 1.1 6.1 6.0 0.0 3.3 1.4 0.0 3.1 0.0 0.2 10.8 0.0 2.8 1.5 0.1 0.0 2.2 0.0 0.0 1.5 0.5 0.0 29.7 5.6 0.6 4.0 0.0 1.8 2.1 0.5 0.0 0.1 0.6 0.0 0.2 1.0 0.0 1.4 5.8 2.7 0.5 1.3 0.6 12.1 1.1 SASH1 "dJ323M4.1, KIAA0790, SH3D6A" ENSG00000111961 "SAM and SH3 domain containing 1" O94885 6 148272304-148552048 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis, Palmoplantar keratoderma, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 194.8;Astrocytes: 426.7;Microglial cells: 179.9;Oligodendrocyte precursor cells: 186.5;Oligodendrocytes: 328.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "classical monocyte: 1.2;intermediate monocyte: 2.6;non-classical monocyte: 1.3" "Lineage enriched" "Detected in single" 26 "monocytes: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 198.0;ASC TERT1: 74.7;fHDF/TERT166: 73.4;HUVEC TERT2: 75.0;WM-115: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029947, HPA029949" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA029947: AB_10598915, HPA029949: AB_10602280" "unprognostic (9.71e-2)" "unprognostic (4.74e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.55e-2)" "unprognostic (4.79e-3)" "unprognostic (6.69e-2)" "unprognostic (4.76e-2)" "unprognostic (2.06e-1)" "unprognostic (8.65e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-1)" "unprognostic (2.13e-3)" "unprognostic (5.45e-2)" "unprognostic (3.53e-1)" "unprognostic (8.04e-3)" "unprognostic (1.54e-1)" 76.1 6.1 45.5 6.6 62.5 0.3 47.6 58.2 35.4 24.5 10.3 18.1 6.8 13.6 5.1 45.2 15.9 19.7 17.0 40.0 43.0 15.0 9.3 26.5 6.2 72.1 60.0 6.5 9.5 14.2 5.1 30.3 59.4 11.6 9.8 15.4 19.8 9.2 17.9 31.0 11.8 16.1 49.1 13.7 9.5 4.6 65.1 5.1 39.0 22.5 7.8 13.8 27.9 59.3 4.8 2.9 23.6 7.9 198.0 74.7 3.9 27.3 65.6 20.2 30.7 6.2 5.7 0.0 14.1 73.4 10.1 5.7 7.3 6.7 16.9 0.0 5.3 0.0 13.6 5.7 6.1 0.0 1.3 35.1 6.8 30.6 8.3 8.3 75.0 0.0 0.4 0.1 19.1 5.5 0.0 0.0 6.9 2.6 3.8 0.0 16.8 0.2 15.1 15.1 0.9 0.0 8.4 30.8 21.5 6.1 2.4 14.0 65.6 19.7 4.0 63.1 5.9 0.0 0.0 0.0 31.6 0.0 95.6 0.0 1.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 45.5 62.5 58.2 35.4 40.0 43.0 72.1 60.0 59.4 49.1 65.1 59.3 194.8 16.0 21.7 426.7 0.6 41.0 6.2 5.1 29.6 21.9 17.7 24.0 18.5 5.7 18.3 46.0 6.2 20.6 0.8 4.4 7.9 3.1 0.8 45.3 36.2 104.7 4.8 0.0 16.4 2.4 59.5 66.5 8.2 40.1 2.5 2.3 60.3 8.1 8.8 3.3 120.7 5.3 10.2 42.4 18.5 1.6 18.3 15.6 42.7 179.9 4.9 100.4 0.0 186.5 328.6 1.5 2.9 28.2 1.3 6.4 2.3 15.0 15.5 4.7 78.9 49.9 73.2 0.5 3.7 46.3 33.0 32.7 1.6 3.1 7.2 7.4 SBDS "CGI-97, FLJ10917, SDS, SWDS" ENSG00000126524 "SBDS ribosome maturation factor" Q9Y3A5 7 66987680-66995587 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2042.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028891 Approved Supported Nucleoplasm,Cytosol NA NA 190000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA028891: AB_10601500" "prognostic unfavorable (1.49e-4)" "unprognostic (1.87e-2)" "unprognostic (5.73e-2)" "unprognostic (1.71e-3)" "unprognostic (8.06e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.07e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (6.99e-2)" "unprognostic (7.84e-3)" "unprognostic (4.59e-1)" "unprognostic (1.04e-2)" "unprognostic (9.38e-3)" "unprognostic (1.83e-1)" "unprognostic (2.30e-1)" "unprognostic (5.06e-3)" 139.1 107.5 136.1 57.9 152.1 157.2 113.7 151.2 168.3 97.3 115.8 143.6 127.8 117.2 83.3 128.6 99.2 84.9 238.0 133.1 148.4 117.8 126.8 113.8 43.8 156.2 142.3 90.1 89.3 145.0 87.4 106.2 155.0 107.9 111.6 90.3 80.7 122.6 374.0 92.0 114.2 128.2 152.6 57.3 104.6 60.9 143.4 38.8 107.0 263.3 52.5 113.9 90.7 169.7 168.3 68.9 59.9 54.6 212.7 157.9 67.0 281.4 225.4 206.1 157.1 143.1 83.0 62.2 209.7 253.5 136.3 80.1 101.7 164.3 219.4 59.8 136.4 31.1 125.9 86.6 188.9 78.1 40.8 144.0 215.1 157.0 269.8 105.9 129.2 39.7 227.2 65.0 324.2 100.0 41.8 112.4 67.2 227.3 165.9 31.3 132.6 129.3 218.1 73.6 91.7 63.7 142.3 235.5 194.3 131.0 176.2 64.8 176.4 276.5 96.7 142.5 205.4 40.6 51.4 141.0 95.7 125.5 157.4 75.5 33.2 61.4 64.7 37.7 81.7 62.8 82.7 75.2 33.4 59.9 104.4 85.7 13.0 51.8 35.1 45.4 80.2 62.2 136.1 152.1 151.2 168.3 133.1 148.4 156.2 142.3 155.0 152.6 143.4 169.7 169.9 304.5 128.0 10.7 101.6 464.2 466.2 213.2 145.7 73.7 118.5 154.0 286.6 108.7 160.3 92.0 12.5 130.5 98.0 270.9 262.2 177.4 583.0 93.0 131.2 153.2 101.9 51.3 12.5 165.7 232.1 197.7 96.8 128.2 150.0 29.7 138.5 102.1 107.0 58.9 15.3 221.9 142.4 47.2 238.1 2042.9 127.1 74.8 256.1 11.2 66.5 161.9 30.9 7.5 36.0 300.0 242.2 168.5 117.5 267.2 359.3 264.6 75.6 56.8 164.3 512.9 266.2 86.3 47.9 129.9 430.0 398.5 144.5 132.2 165.4 318.5 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.7;brain: 353.6" "Cell type enhanced" "Detected in many" "Astrocytes: 248.4;Oligodendrocyte precursor cells: 892.7;Oligodendrocytes: 513.6" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 69.2;RPTEC TERT1: 90.1" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favorable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" 6.8 156.7 226.1 3.7 283.7 2.9 5.7 302.5 260.4 10.6 85.2 12.9 4.5 12.5 97.6 5.8 18.7 9.3 8.1 212.6 277.4 33.1 2.5 15.0 3.0 353.6 272.7 93.7 40.9 18.7 31.4 7.5 291.0 12.7 4.0 70.2 18.0 24.3 1.3 8.2 6.0 12.0 314.1 4.5 10.6 33.3 255.6 10.6 35.5 4.2 4.4 7.7 8.7 316.2 11.2 7.1 36.0 18.6 19.7 12.5 0.6 69.2 33.9 29.7 22.8 0.5 1.7 22.5 23.5 14.5 8.0 19.9 10.6 7.6 37.0 4.4 4.7 1.0 8.1 0.7 2.9 10.0 6.9 10.0 30.6 5.9 5.2 30.5 48.4 25.8 1.3 2.2 15.6 4.4 42.6 2.1 2.6 0.2 5.0 35.6 21.5 17.9 90.1 11.2 20.1 11.5 11.4 0.5 6.8 3.5 1.3 5.0 59.5 31.5 18.1 11.9 18.9 6.0 2.5 2.2 15.3 10.5 9.0 1.9 0.6 0.1 3.9 0.2 2.5 0.2 0.8 2.3 0.3 0.4 0.7 2.6 0.7 1.1 0.4 0.7 0.2 1.2 226.1 283.7 302.5 260.4 212.6 277.4 353.6 272.7 291.0 314.1 255.6 316.2 1.4 44.8 3.9 248.4 0.8 10.7 16.5 16.3 5.7 101.4 6.8 4.8 2.9 27.1 25.7 27.6 25.0 1.9 3.9 0.4 13.7 79.7 115.0 13.5 9.3 7.7 7.7 0.0 84.3 46.9 0.2 16.8 2.6 14.8 0.0 10.5 10.4 0.2 1.1 101.0 107.0 0.3 10.2 1.3 3.3 100.3 55.0 1.8 3.6 23.4 1.9 145.3 4.1 892.7 513.6 8.9 0.0 58.3 0.7 11.3 0.2 20.4 13.0 14.6 6.6 3.6 11.5 2.9 3.7 2.7 7.2 0.1 3.2 137.4 2.0 9.3 SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 3079.0" "Cell type enriched" "Detected in some" 4 "Club cells: 43564.7" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 71 "HaCaT: 1977.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" NA NA 13000000 "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" 1.1 2.0 0.6 0.9 0.7 0.1 0.3 1.3 1.1 0.6 0.3 0.2 0.4 0.2 0.7 11.0 334.2 0.2 0.6 0.5 0.6 0.2 0.4 3079.0 0.2 0.6 0.9 2.0 1.9 0.0 2.4 1.7 0.5 85.1 0.0 0.2 0.5 0.9 0.3 0.3 1.6 0.0 0.5 7.2 4.3 0.2 1.0 2.8 0.4 0.0 5.9 0.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 1977.1 0.0 0.3 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.3 27.9 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 1.1 0.0 0.0 0.6 1.4 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.0 0.0 1.0 2.0 0.0 1.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.3 1.1 0.5 0.6 0.6 0.9 0.5 0.5 1.0 0.5 0.0 1125.0 2573.3 0.0 0.0 0.0 71.4 3938.5 0.0 0.0 0.0 0.0 0.0 0.0 43564.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 113.5 0.0 0.0 0.1 0.0 0.0 304.5 0.0 0.5 691.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4534.8 0.0 0.0 0.7 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.0 0.0 134.7 0.0 0.0 9997.0 0.0 0.0 0.0 850.3 0.0 0.0 3.9 0.0 0.0 83.7 0.0 0.0 800.2 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.1;lymphoid tissue: 12.1" "Cell type enhanced" "Detected in many" "dendritic cells: 31.7;Early spermatids: 72.1;Late spermatids: 168.4;NK-cells: 35.0;T-cells: 73.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 48.2;MAIT T-cell: 47.7;memory CD4 T-cell: 74.8;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.1;naive CD8 T-cell: 59.5;NK-cell: 53.2" "Group enriched" "Detected in many" 6 "NK-cells: 53.2;T-cells: 74.8" "Cell line enriched" "Detected in some" 5 "HDLM-2: 65.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA063326: AB_2684986, HPA065958: AB_2685587" "unprognostic (4.00e-5)" "unprognostic (2.10e-3)" "unprognostic (4.71e-2)" "unprognostic (4.24e-3)" "unprognostic (1.38e-3)" "unprognostic (4.75e-4)" "unprognostic (3.84e-3)" "unprognostic (6.65e-3)" "unprognostic (4.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-4)" "unprognostic (3.68e-1)" "unprognostic (3.77e-4)" "unprognostic (8.65e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-3)" "unprognostic (5.09e-3)" 0.6 0.8 0.8 7.2 0.6 3.3 1.0 1.2 0.7 0.5 0.2 2.3 10.1 0.5 4.6 0.9 0.7 1.4 0.6 0.6 0.9 0.6 1.6 1.7 12.1 0.5 0.5 0.6 0.7 0.2 1.9 0.3 0.3 0.6 2.0 0.9 1.0 0.4 0.4 0.9 8.2 0.5 0.1 7.4 2.8 2.2 1.3 9.3 0.8 0.2 9.8 1.1 0.7 0.6 0.1 0.1 0.1 0.1 0.1 0.3 0.8 0.1 0.0 0.0 0.0 1.4 0.2 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.1 65.1 0.0 0.1 0.4 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.3 0.1 0.1 13.8 0.2 0.1 0.1 0.0 0.1 0.2 0.3 0.1 0.3 0.2 0.7 0.1 0.1 0.1 4.2 0.3 3.5 48.2 0.1 47.7 10.1 74.8 65.7 0.2 5.8 69.1 59.5 6.6 53.2 0.4 1.2 5.8 26.6 0.8 0.6 1.2 0.7 0.6 0.9 0.5 0.5 0.3 0.1 1.3 0.6 0.5 0.0 0.0 0.7 18.0 1.5 0.0 0.0 0.6 0.6 0.4 0.4 1.1 0.0 0.0 0.0 0.0 1.3 31.7 0.4 0.0 1.2 72.1 0.0 0.1 0.7 0.0 1.3 2.7 0.0 0.2 1.0 4.6 0.1 1.3 0.0 1.1 1.8 0.2 1.7 2.5 1.4 0.0 0.8 1.4 168.4 0.9 1.2 3.6 1.9 2.0 0.0 35.0 0.5 0.1 0.1 2.6 0.7 11.6 0.0 5.5 0.4 0.7 0.0 0.0 0.3 0.6 1.1 0.5 0.3 0.1 0.1 73.3 0.0 4.7 0.1 SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 102.0;Leydig cells: 100.9;Peritubular cells: 159.9;Sertoli cells: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "HDLM-2: 7.9;HMC-1: 4.5;Karpas-707: 5.8;SK-BR-3: 15.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" 4.6 8.6 3.4 3.4 3.0 0.3 10.2 0.1 1.8 7.8 0.0 35.8 3.4 9.0 6.3 10.1 10.9 3.8 20.6 1.1 7.1 1.8 1.2 27.6 0.5 4.0 7.1 45.4 4.9 0.7 1.0 12.3 5.4 11.0 8.5 10.6 6.1 10.1 7.2 2.4 6.8 7.6 2.9 3.2 7.8 5.6 9.8 3.2 1.2 15.0 0.4 4.7 7.1 1.2 0.1 0.1 0.7 0.9 0.2 0.0 0.8 0.7 0.0 1.3 0.0 0.6 0.2 0.4 0.1 0.0 0.3 0.3 0.1 0.1 0.0 7.9 0.5 0.2 1.5 0.6 0.0 0.2 4.5 0.0 0.0 0.4 0.1 0.4 0.0 0.4 1.2 5.8 0.0 1.0 0.8 0.5 1.1 0.3 0.3 0.0 0.5 0.0 0.1 0.8 0.2 0.4 0.3 15.4 0.0 0.3 0.4 0.1 0.4 0.2 1.0 0.7 0.4 1.0 0.3 1.1 0.2 0.2 0.4 1.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.8 3.4 3.0 0.1 1.8 1.1 7.1 4.0 7.1 5.4 2.9 9.8 1.2 1.4 0.0 1.1 1.0 0.0 0.3 0.2 0.0 5.7 21.5 0.2 0.3 16.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 2.4 0.0 0.3 4.1 0.0 0.0 7.7 0.0 0.0 102.0 0.0 0.0 15.9 0.1 9.3 0.0 0.2 0.0 20.9 0.0 0.0 0.0 1.2 4.1 100.9 1.8 5.4 14.0 0.0 4.9 0.0 14.1 0.3 0.1 0.0 159.9 1.2 0.5 0.0 0.5 0.0 1.8 151.2 16.7 26.1 0.5 1.2 1.7 1.1 0.0 0.2 0.3 0.0 0.3 SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.0;Distal enterocytes: 230.9;Glandular and luminal cells: 189.8;Intestinal goblet cells: 180.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 300.5;HBEC3-KT: 202.4;hTCEpi: 85.3;RPTEC TERT1: 103.7;RT4: 114.1;SK-BR-3: 96.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" 3.4 12.5 0.2 5.6 0.1 0.5 20.6 1.1 0.2 64.7 113.6 66.4 18.7 7.6 43.2 140.1 57.9 17.7 0.7 6.8 0.0 148.5 8.2 62.9 0.2 0.1 0.3 3.5 40.0 0.7 16.6 0.4 0.1 43.7 65.4 0.0 157.3 49.5 0.5 54.6 26.0 2.9 0.1 0.7 63.6 4.7 1.3 1.9 94.3 0.1 12.5 20.8 57.6 0.1 21.6 4.1 0.0 1.9 0.3 0.4 17.6 0.0 0.1 0.1 0.0 6.1 300.5 0.3 0.8 0.1 0.1 14.0 0.0 202.4 0.0 0.0 0.0 0.0 17.5 3.1 20.9 0.0 0.1 5.1 85.3 0.0 61.6 0.4 0.0 0.5 0.0 0.1 0.5 1.9 0.1 0.3 17.6 38.9 0.8 0.2 0.0 0.5 103.7 114.1 1.2 0.1 2.3 96.7 0.1 17.1 22.3 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 1.5 0.0 0.0 1.0 0.5 0.1 0.2 0.1 1.1 0.2 6.8 0.0 0.1 0.3 0.1 0.1 1.3 0.1 1.7 73.7 75.7 0.0 1.3 1.9 25.1 17.0 10.8 0.9 17.7 21.2 0.8 54.3 52.5 114.0 4.2 1.4 1.8 230.9 5.9 45.0 0.5 85.3 17.8 3.2 27.1 0.0 0.3 33.9 0.3 2.0 97.3 189.8 2.5 1.3 1.4 3.2 0.3 1.7 0.2 180.3 63.1 1.9 3.1 0.6 1.8 2.5 0.0 0.0 1.6 0.3 1.0 0.5 0.1 39.4 95.8 1.5 0.3 30.9 12.2 6.2 36.7 1.4 0.0 5.6 4.3 1.2 3.7 48.1 8.8 1.6 3.6 0.2 31.5 42.1 SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Club cells: 64.8;Collecting duct cells: 57.0;Distal enterocytes: 262.8;Ionocytes: 107.8;Paneth cells: 73.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 33.3;RPMI-8226: 9.2;RT4: 18.5;U-266/70: 55.4;U-266/84: 20.2" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" 18.5 0.4 0.0 1.1 0.0 0.2 17.7 1.0 0.0 48.5 0.0 94.2 2.5 2.8 0.1 82.8 3.7 0.5 0.3 0.0 0.0 31.7 0.2 23.9 0.8 0.0 0.0 0.7 2.1 0.3 1.0 3.6 0.1 10.5 35.6 0.0 39.5 2.4 1.4 36.0 4.3 0.8 0.0 3.7 24.1 0.3 0.0 0.7 9.2 0.8 5.4 8.3 56.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 9.2 0.0 18.5 0.2 0.0 0.0 0.5 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 55.4 20.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.7 99.3 28.3 0.0 7.1 3.1 15.4 27.8 5.7 0.0 4.4 3.0 0.7 0.0 64.8 57.0 0.0 0.7 0.1 262.8 0.0 0.0 0.1 11.9 1.6 6.2 7.7 0.0 0.3 0.4 0.3 1.0 36.7 23.4 8.2 0.0 1.1 0.1 0.1 0.0 0.3 21.4 107.8 0.0 0.0 0.2 0.0 1.0 10.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 73.7 0.0 38.7 6.1 0.0 0.1 9.2 0.0 0.0 0.1 0.7 0.1 0.4 29.8 5.4 2.2 1.4 0.0 15.2 19.7 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7;choroid plexus: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 46.4;Muller glia cells: 148.3;Oligodendrocyte precursor cells: 102.1" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" NA NA 240000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" 1.3 0.8 19.0 0.6 20.5 0.7 0.5 20.6 30.7 1.6 15.2 4.4 0.5 1.8 0.9 0.4 2.5 1.5 2.9 19.4 20.3 0.2 0.1 0.4 0.2 22.8 19.9 0.8 0.3 0.0 1.0 0.2 22.5 2.3 0.5 2.3 1.1 3.2 0.5 0.5 0.9 4.7 21.6 0.5 2.8 10.8 19.4 0.0 0.3 0.0 0.1 2.0 0.8 24.7 0.1 0.0 0.6 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.5 0.2 0.1 3.5 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 17.1 1.8 0.5 0.3 0.2 0.4 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.3 1.2 0.5 0.5 0.3 0.1 0.1 19.0 20.5 20.6 30.7 19.4 20.3 22.8 19.9 22.5 21.6 19.4 24.7 1.3 0.0 3.0 46.4 1.0 3.6 1.1 0.0 0.0 14.5 2.4 3.9 1.3 0.0 0.7 0.0 37.5 0.2 3.3 0.3 0.0 0.3 18.3 0.7 1.7 2.1 1.2 0.0 19.0 0.0 0.4 17.3 1.1 0.4 8.9 0.9 4.2 0.3 0.6 16.8 20.9 0.5 0.0 3.3 2.6 32.3 26.1 3.8 23.2 2.8 1.9 148.3 2.1 102.1 26.4 0.2 0.1 20.7 1.0 1.9 0.4 0.3 0.8 28.3 13.1 2.4 20.3 3.1 2.4 0.1 2.6 0.7 3.1 0.5 0.3 1.0 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Muller glia cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 326.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" 13.9 27.9 112.4 13.1 118.9 8.1 14.3 128.2 117.9 22.2 52.2 27.5 6.5 27.4 16.2 19.0 26.0 16.5 19.8 112.5 129.0 23.7 2.6 16.4 14.3 112.5 159.0 32.4 36.7 54.5 34.0 15.8 115.5 27.9 10.4 102.5 18.0 37.2 2.4 11.1 15.8 34.3 116.1 10.8 19.3 23.0 122.5 28.9 13.5 11.0 21.6 22.0 17.8 127.1 106.3 75.0 119.9 48.6 83.1 126.9 0.5 97.0 128.8 102.5 110.0 87.1 81.8 13.0 83.7 124.7 227.3 46.7 137.7 41.2 148.9 0.6 29.0 43.8 49.7 56.6 105.9 0.3 0.5 106.5 58.1 93.5 49.6 139.4 95.9 28.0 0.5 33.3 146.6 59.5 15.5 0.1 109.4 0.2 79.6 0.3 127.7 1.1 71.7 51.5 43.7 103.1 99.9 64.1 112.5 149.7 86.3 6.9 106.7 132.2 113.3 1.7 123.7 10.8 177.0 1.1 62.4 0.5 326.5 3.7 3.4 10.3 0.9 14.1 10.7 14.0 0.2 1.0 10.9 7.6 0.7 1.4 0.5 7.1 25.4 10.8 0.0 3.5 112.4 118.9 128.2 117.9 112.5 129.0 112.5 159.0 115.5 116.1 122.5 127.1 5.9 28.9 14.1 42.7 15.4 3.1 12.6 14.0 14.2 66.9 7.6 5.2 15.8 20.0 22.3 33.1 45.9 0.4 16.2 1.1 15.6 24.1 61.1 7.3 11.9 10.9 12.1 2.5 52.0 25.1 1.9 17.2 5.6 6.7 8.2 22.9 1.8 0.3 5.4 69.0 51.4 0.7 14.2 8.8 13.9 68.1 13.7 11.1 7.2 16.9 11.5 80.8 12.3 31.2 35.6 21.2 17.3 21.1 12.5 17.4 0.1 2.8 29.2 41.1 6.6 9.6 11.9 3.1 11.0 5.1 1.7 1.0 2.8 8.5 1.2 22.3 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 141.8;intestine: 136.9;stomach 1: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 782.5;Pancreatic endocrine cells: 755.4;Paneth cells: 948.5;Proximal enterocytes: 470.3;Urothelial cells: 641.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.6;OE19: 57.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" 7.3 3.4 19.9 10.1 20.7 0.7 6.9 16.3 24.3 25.8 15.2 85.8 136.9 5.7 9.0 141.8 4.3 41.8 4.6 19.6 20.2 16.0 18.1 20.9 1.3 17.2 17.9 3.5 15.2 2.5 3.9 3.3 17.4 6.5 55.5 1.0 29.8 2.5 2.8 62.9 133.0 3.6 16.9 3.1 101.8 5.6 20.3 1.5 14.6 1.4 13.7 38.2 49.9 18.0 10.9 0.5 1.4 0.5 5.8 5.1 0.9 3.2 6.3 2.8 2.7 2.3 18.6 1.1 2.1 1.2 2.0 8.2 0.5 15.5 1.4 0.4 1.0 0.9 0.6 1.5 5.8 1.1 1.2 1.8 10.8 2.2 2.2 6.0 9.6 2.0 1.5 0.7 1.1 2.6 1.7 3.0 1.3 57.3 0.7 1.6 0.7 2.2 1.2 14.4 2.4 1.9 1.5 9.3 3.6 0.6 0.4 0.9 6.5 1.5 0.6 2.8 1.2 2.8 2.7 1.1 0.7 4.1 0.9 0.1 0.8 1.9 0.9 0.3 0.7 0.2 1.2 0.9 1.0 0.4 1.0 1.8 0.8 0.9 0.6 0.7 2.3 0.7 19.9 20.7 16.3 24.3 19.6 20.2 17.2 17.9 17.4 16.9 20.3 18.0 15.6 16.0 4.2 0.0 4.1 55.7 112.0 198.1 3.4 1.0 4.9 4.8 0.8 72.9 172.6 16.5 0.0 1.8 1.0 782.5 27.4 114.5 17.1 25.8 11.7 14.1 35.9 0.0 0.0 209.7 1.1 4.6 201.8 85.4 8.9 1.0 7.1 5.1 0.9 1.7 0.0 150.8 156.6 1.9 6.4 1.9 1.5 1.8 8.8 0.0 2.3 1.0 2.1 0.0 0.0 755.4 948.5 0.0 0.7 107.0 470.3 1.8 89.6 0.9 0.0 1.7 9.9 5.0 7.6 31.1 95.6 1.6 3.5 2.0 109.2 641.9 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 685.6;Muller glia cells: 544.7;Plasma cells: 1164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 523.5;Karpas-707: 546.2;RPMI-8226: 1150.0;U-266/70: 587.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 24.6 76.7 110.0 86.5 117.5 63.1 81.8 122.9 140.5 57.8 94.4 92.3 126.7 40.1 284.6 42.5 41.4 47.3 30.0 112.9 146.4 70.2 219.0 62.7 104.2 137.3 130.2 29.9 374.0 153.9 155.2 28.4 136.8 225.7 78.2 108.1 397.3 62.3 15.7 29.7 97.8 30.1 123.7 81.4 138.5 28.1 113.5 53.0 163.7 20.0 117.8 59.4 21.2 135.8 82.4 100.0 52.9 74.1 31.9 6.8 64.7 72.4 62.9 89.9 55.2 78.3 42.5 176.8 109.9 46.6 67.6 82.8 84.7 59.0 58.4 523.5 113.8 58.5 69.3 242.3 99.3 199.4 87.6 20.4 140.7 56.2 161.1 20.2 33.7 78.4 67.4 546.2 34.6 100.0 79.0 79.2 48.1 140.4 60.5 72.8 50.0 1150.0 67.5 76.1 223.2 90.5 43.1 162.5 252.8 29.9 76.0 148.5 24.7 98.5 45.4 36.5 86.9 587.3 434.4 176.0 99.4 131.8 124.5 76.4 70.7 57.9 146.1 97.6 187.6 197.8 150.4 142.5 78.8 127.9 77.7 105.4 12.2 108.3 108.8 299.6 223.7 222.1 110.0 117.5 122.9 140.5 112.9 146.4 137.3 130.2 136.8 123.7 113.5 135.8 64.8 28.9 120.7 19.2 295.9 32.6 49.3 92.4 12.5 63.6 120.0 128.3 59.3 144.4 102.5 60.7 50.1 70.8 148.7 76.3 88.0 164.4 45.4 58.7 34.2 60.3 339.3 43.8 12.2 263.1 109.1 29.2 60.6 147.1 47.5 21.5 56.4 224.7 112.9 50.5 13.3 223.1 685.6 37.1 56.9 18.8 12.5 63.9 256.1 10.3 46.4 544.7 96.8 17.1 31.2 148.9 78.4 23.0 1164.8 380.9 99.3 118.8 81.3 89.3 6.6 23.1 70.6 110.2 81.5 35.5 45.5 149.7 92.3 40.1 88.3 79.2 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.5;Cholangiocytes: 11.5;Collecting duct cells: 12.9;Ductal cells: 6.6;Muller glia cells: 18.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "K-562: 12.3;RPTEC TERT1: 21.8;SiHa: 6.6" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" 1.4 1.4 5.3 0.3 4.6 2.1 3.9 4.5 4.7 3.5 5.9 0.5 0.6 3.2 21.2 0.3 1.7 4.5 0.3 4.4 5.0 8.4 0.4 11.9 0.4 8.6 6.2 2.4 5.5 30.5 2.5 0.5 8.8 1.7 0.3 5.0 0.4 2.6 0.2 10.0 0.5 2.2 5.2 0.4 1.2 5.4 8.7 0.3 0.3 0.8 0.6 0.4 0.4 4.9 0.2 0.1 0.9 0.3 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.2 0.5 0.3 1.1 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.0 0.3 0.3 0.1 0.2 0.4 0.0 0.1 0.1 0.1 0.7 0.0 0.1 12.3 0.2 0.0 0.5 0.1 0.4 0.5 0.0 0.1 0.2 0.0 0.1 21.8 0.2 0.2 0.1 6.6 0.1 0.0 0.2 1.8 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.1 0.1 0.5 0.0 5.3 4.6 4.5 4.7 4.4 5.0 8.6 6.2 8.8 5.2 8.7 4.9 0.0 12.8 10.5 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.4 0.5 0.3 11.5 3.7 12.9 0.0 0.0 0.0 0.0 1.9 6.6 0.0 0.3 0.4 1.0 0.0 0.0 0.7 0.8 0.0 0.2 0.0 1.5 1.3 0.2 0.7 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.6 18.6 0.0 1.5 0.6 1.8 0.0 0.7 0.0 0.1 0.0 2.9 0.0 0.5 0.0 2.7 0.1 0.9 0.4 0.0 0.0 0.1 0.9 0.0 0.0 0.2 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 373.6;Breast myoepithelial cells: 436.2;Collecting duct cells: 309.0;Distal tubular cells: 309.1;Endometrial stromal cells: 349.5;Exocrine glandular cells: 586.6;Smooth muscle cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Cell line enhanced" "Detected in many" "BJ: 152.2;BJ hTERT+: 143.8;HHSteC: 183.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" 241.8 95.4 126.7 55.7 126.7 2.9 239.8 127.3 170.7 458.8 189.9 575.4 37.2 600.2 14.8 86.1 437.8 28.6 227.2 130.0 149.3 162.5 36.7 157.5 25.9 137.1 138.6 262.4 154.3 94.7 241.1 32.2 131.0 339.6 16.4 8.1 198.8 140.1 109.9 114.8 193.9 85.3 139.6 97.6 285.6 42.1 142.1 10.2 225.8 18.6 15.3 462.3 290.7 132.3 12.8 25.7 7.4 42.7 68.8 80.5 82.2 152.2 143.8 69.2 50.0 0.8 2.0 1.6 30.9 89.9 31.2 1.2 6.9 9.2 4.7 7.0 25.6 2.7 7.8 13.3 183.7 0.0 13.1 78.5 27.1 33.1 12.6 33.1 9.0 2.2 2.4 14.7 17.9 6.6 0.5 1.4 9.6 11.8 27.3 0.1 0.1 18.1 11.1 0.1 16.2 35.7 47.3 41.6 0.7 2.5 57.5 0.9 30.9 20.8 59.0 77.8 0.1 13.2 6.5 1.0 83.1 0.2 13.8 18.3 10.5 5.1 105.3 19.9 137.9 154.8 174.5 127.0 6.4 129.5 233.0 137.8 8.2 39.1 40.1 2.5 179.0 102.6 126.7 126.7 127.3 170.7 130.0 149.3 137.1 138.6 131.0 139.6 142.1 132.3 168.6 54.5 126.5 0.0 38.8 0.0 0.0 0.0 0.0 0.0 373.6 436.2 0.0 0.0 32.2 309.0 0.0 11.7 23.2 0.0 309.1 101.2 0.0 22.8 349.5 61.8 0.0 0.0 0.0 586.6 149.5 161.3 0.0 18.1 30.3 30.8 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 42.9 0.0 0.0 0.0 0.0 166.2 0.0 0.0 22.3 0.0 0.0 152.5 20.4 0.0 0.0 0.0 225.6 0.0 0.0 0.0 0.0 23.4 24.8 30.5 0.0 0.0 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 90.1;Extravillous trophoblasts: 266.8;Fibroblasts: 40.1;Hofbauer cells: 52.0;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 495.8;fHDF/TERT166: 604.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" 84.8 13.0 34.6 27.5 46.5 7.9 39.3 24.3 51.4 40.4 0.0 50.1 21.8 33.8 18.0 22.5 17.4 45.4 30.8 40.5 13.7 52.4 33.9 40.5 24.1 5.2 8.5 20.0 22.3 17.3 11.3 84.1 4.5 21.0 40.4 22.3 11.6 26.1 26.0 13.3 35.3 40.6 0.0 25.6 25.2 7.8 16.6 12.7 21.1 18.3 22.8 39.3 21.5 50.6 87.6 34.9 328.1 293.8 192.8 152.9 94.6 495.8 382.7 110.6 154.5 64.3 62.9 2.0 100.9 604.4 51.9 36.6 109.8 73.8 171.2 114.0 36.7 171.2 44.6 47.1 168.0 93.0 69.7 195.5 34.4 160.2 59.8 87.7 169.0 34.3 72.0 46.6 331.2 50.4 122.8 3.3 111.1 71.4 18.1 142.6 372.8 10.1 62.6 94.0 112.1 83.6 96.2 54.4 77.9 209.9 49.5 37.3 184.4 368.7 109.4 182.8 93.1 28.5 24.3 1.1 140.5 10.0 76.4 12.2 2.4 32.5 8.1 2.2 5.0 3.6 9.2 11.2 7.8 6.7 3.5 9.4 0.6 38.4 7.4 20.8 5.8 6.6 34.6 46.5 24.3 51.4 40.5 13.7 5.2 8.5 4.5 0.0 16.6 50.6 33.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 90.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 266.8 40.1 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 60.5 5.6 0.0 0.0 0.0 SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 52.0;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.0;hTERT-RPE1: 19.4;SK-MEL-30: 32.8" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" 46.6 165.0 832.1 5.0 1011.1 0.5 33.5 861.9 1288.2 13.9 593.0 15.3 4.9 12.4 6.9 5.9 14.2 17.1 56.3 774.4 799.2 31.8 56.6 39.6 14.4 864.7 904.6 15.8 8.7 9.4 23.1 20.9 859.8 8.6 5.3 404.5 9.2 6.5 10.8 11.1 12.1 11.7 798.0 49.5 11.5 25.7 925.2 4.4 23.2 13.7 7.3 12.2 12.1 1080.0 0.0 0.6 1.2 3.6 1.4 0.2 0.6 0.2 0.5 2.1 2.4 0.2 0.5 0.0 5.1 0.8 3.2 0.4 1.8 1.4 0.5 0.3 0.9 1.3 0.3 7.6 14.0 0.1 0.7 7.2 2.9 0.5 2.6 19.4 0.6 1.9 0.0 3.8 0.2 0.5 0.0 0.1 0.6 0.0 0.9 0.2 0.0 1.6 0.0 0.1 3.9 2.1 0.1 0.2 32.8 1.6 0.8 0.4 0.0 0.3 1.6 0.0 1.4 1.0 0.6 0.0 1.1 0.0 0.4 0.0 3.6 0.8 4.9 0.5 1.5 1.6 1.0 1.3 3.7 0.3 1.8 1.4 1.9 1.0 0.0 0.2 0.7 3.6 832.1 1011.1 861.9 1288.2 774.4 799.2 864.7 904.6 859.8 798.0 925.2 1080.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.6;pituitary gland: 91.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.6;Cone photoreceptor cells: 185.6;Enteroendocrine cells: 132.5;Horizontal cells: 188.4;Rod photoreceptor cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" 4.6 23.2 47.3 1.4 43.6 0.1 4.5 37.0 101.6 11.8 0.0 4.5 10.3 9.0 0.7 1.1 4.0 9.6 2.3 43.7 93.1 7.8 0.6 4.5 0.9 69.2 29.2 5.4 41.2 21.3 91.9 3.0 62.5 14.4 3.4 25.8 22.1 4.3 1.0 2.4 5.8 4.1 21.1 1.9 16.6 11.2 46.4 0.4 1.0 0.0 1.4 3.1 1.8 57.3 1.4 11.6 0.9 11.0 0.1 0.5 7.7 14.4 6.7 13.3 7.3 17.2 53.8 5.8 76.7 17.5 11.1 4.9 4.4 3.4 4.0 0.1 9.6 0.9 9.2 35.7 28.7 0.0 33.9 32.3 6.5 15.8 4.3 48.1 1.0 5.1 1.8 34.5 6.7 59.4 0.2 0.1 17.2 19.6 19.8 0.0 0.0 1.6 12.1 5.1 51.3 41.2 4.9 36.5 2.3 9.1 34.3 51.3 0.6 44.3 21.6 0.3 0.9 3.9 3.6 0.3 53.8 9.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 43.6 37.0 101.6 43.7 93.1 69.2 29.2 62.5 21.1 46.4 57.3 3.2 3.2 16.4 4.2 0.8 2.9 9.4 6.2 2.8 236.6 49.6 30.6 8.6 77.2 5.5 3.7 185.6 0.3 0.5 19.9 0.0 61.7 2.8 25.1 48.2 4.9 132.5 0.0 28.6 39.4 2.7 12.2 34.7 33.4 1.3 3.5 2.5 0.2 1.3 188.4 46.3 32.9 10.2 0.3 0.0 5.4 1.2 1.0 12.4 3.7 0.6 20.8 0.0 5.5 13.1 45.2 22.1 1.9 1.4 23.5 15.3 5.0 3.4 230.3 13.1 0.9 15.2 8.2 4.7 1.0 1.4 1.4 0.7 26.8 29.0 9.1 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFTPA2 "COLEC5, SP-A2" ENSG00000185303 "Surfactant protein A2" Q8IWL1 10 79555852-79560407 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 404 "lung: 10798.8" "Cell type enriched" "Detected in some" 10 "Alveolar cells type 2: 16905.3" "Cancer enriched" "Detected in many" 21 "lung cancer: 863.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "BEWO: 7.3;NB-4: 8.3;RPMI-8226: 26.1;U-2197: 14.7" "CAB002439, HPA042638, HPA045752, HPA049368" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB002439: AB_564143, HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" "unprognostic (4.99e-2)" "unprognostic (4.38e-2)" "unprognostic (4.29e-2)" "unprognostic (1.05e-1)" "unprognostic (5.78e-2)" "unprognostic (5.08e-1)" "unprognostic (4.94e-2)" "unprognostic (1.68e-3)" "unprognostic (3.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.69e-3)" 0.7 12.1 0.4 4.6 0.6 0.0 1.0 3.1 0.9 1.4 0.0 1.4 0.0 0.2 0.1 0.4 0.2 0.0 1.1 0.5 0.4 0.4 1.1 10798.8 0.0 1.2 0.0 6.5 1.3 0.0 0.4 2.3 1.3 26.7 2.6 0.2 0.4 8.3 1.0 1.1 0.5 0.1 0.0 6.7 10.5 0.5 0.3 2.7 0.8 0.0 0.1 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.3 0.4 0.0 0.0 0.2 0.0 26.1 0.0 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 14.7 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.6 3.1 0.9 0.5 0.4 1.2 0.0 1.3 0.0 0.3 0.6 0.0 1593.0 16905.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 329.9 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.2 0.0 0.0 22.3 1.8 0.0 0.3 3.1 0.0 22.0 0.0 0.2 431.4 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.2 2.0 0.0 0.0 1.0 0.0 0.1 135.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.7 0.0 2.4 0.1 SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Hepatocytes: 21.2;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 38.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" 1.5 1.1 1.2 1.9 2.8 3.0 2.8 3.9 1.7 1.6 3.6 1.9 2.5 2.7 3.6 1.4 3.6 1.1 0.6 1.8 0.8 17.9 4.2 1.6 2.6 1.0 0.5 3.4 3.1 12.7 2.7 3.4 1.2 2.2 3.0 2.7 4.9 1.3 0.7 1.9 1.9 1.1 0.2 2.1 3.3 1.2 1.8 3.2 3.8 0.2 1.9 0.9 0.7 2.1 4.2 2.3 3.5 3.7 1.3 0.9 5.1 1.4 0.6 1.8 0.9 7.2 1.9 9.1 2.7 1.2 1.0 3.0 0.7 4.8 1.0 1.6 2.8 13.1 4.4 4.5 0.6 7.5 1.1 1.0 0.7 1.8 1.8 1.1 1.7 7.7 6.0 4.2 1.1 4.0 11.5 2.5 2.3 4.0 0.8 5.5 4.3 1.3 1.7 3.5 2.6 2.5 1.2 3.1 0.6 1.4 38.4 1.6 1.2 1.4 4.4 1.8 3.1 4.6 6.5 7.9 1.7 9.0 1.2 1.6 0.5 0.2 1.9 0.2 1.7 0.8 1.9 2.0 0.7 2.5 3.0 2.5 0.9 1.9 0.3 1.7 2.0 0.7 1.2 2.8 3.9 1.7 1.8 0.8 1.0 0.5 1.2 0.2 1.8 2.1 1.0 0.0 10.1 5.2 3.8 0.9 3.0 0.8 4.0 6.1 7.3 5.2 2.5 4.3 2.0 1.8 33.3 9.1 2.4 2.5 9.8 1.9 0.8 7.3 4.2 2.2 3.6 4.2 5.4 2.8 4.4 3.2 8.2 10.0 0.0 9.2 5.0 21.2 9.6 0.0 5.5 5.0 0.0 7.5 0.6 0.5 2.1 2.4 0.0 8.4 0.8 1.1 4.1 7.1 2.9 1.4 0.8 1.5 6.7 4.4 2.4 43.1 0.4 15.1 0.0 2.7 1.7 1.2 1.3 3.3 1.3 4.5 2.8 2.6 7.3 2.9 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Group enriched" "Detected in many" 4 "Astrocytes: 365.7;Cardiomyocytes: 107.8;Excitatory neurons: 193.0;Inhibitory neurons: 161.2;Microglial cells: 124.6;Oligodendrocyte precursor cells: 417.2;Oligodendrocytes: 196.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.1;fHDF/TERT166: 25.7;LHCN-M2: 12.7;RH-30: 18.2;SK-MEL-30: 27.0;U-138 MG: 24.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" 5.4 4.2 3.2 2.1 2.0 0.0 3.3 1.6 3.6 6.8 0.0 7.9 2.0 8.2 2.5 6.2 2.9 9.3 39.1 2.9 2.7 1.3 2.0 5.0 0.4 4.2 3.8 8.8 1.0 9.9 1.5 0.6 4.3 6.0 3.6 1.6 1.9 5.2 42.9 1.6 2.7 13.4 3.9 1.4 2.9 1.3 2.0 0.7 17.8 33.3 0.5 6.6 3.1 6.6 0.0 6.4 0.0 0.0 5.8 9.2 0.0 16.1 5.5 0.0 0.2 0.0 0.0 0.0 0.0 25.7 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.5 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 27.0 0.0 0.0 0.0 0.0 24.1 0.0 4.3 0.0 0.1 0.1 0.0 4.1 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.0 1.6 3.6 2.9 2.7 4.2 3.8 4.3 3.9 2.0 6.6 0.7 0.0 0.5 365.7 0.0 3.6 0.0 0.0 0.0 3.5 4.0 2.2 107.8 0.0 0.0 0.0 54.2 0.0 1.6 0.1 0.0 0.1 6.9 6.1 1.5 1.7 1.8 0.0 193.0 0.0 0.0 27.4 0.0 16.3 0.0 11.3 3.3 1.6 0.2 21.9 161.2 0.0 0.0 0.0 2.5 13.3 19.0 0.8 24.9 124.6 0.0 0.3 0.0 417.2 196.4 0.0 0.0 15.4 0.7 0.8 0.0 0.3 0.0 1.2 0.0 38.5 5.9 0.0 0.4 0.5 3.1 0.1 1.0 9.4 0.0 0.2 SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 7 "dendritic cells: 77.6;NK-cells: 138.0;T-cells: 108.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Group enriched" "Detected in some" 6 "HDLM-2: 101.1;JURKAT: 193.0;Karpas-707: 201.3;MOLT-4: 257.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" 1.4 1.1 0.0 10.8 0.1 5.4 1.2 0.1 0.2 0.9 0.1 1.6 1.5 0.6 0.6 1.1 0.5 4.1 0.3 0.1 0.1 0.4 2.8 3.2 38.4 0.2 0.1 0.4 0.2 0.2 0.2 0.3 0.1 1.1 1.5 0.0 1.3 0.3 0.3 0.4 2.5 0.6 0.2 14.7 2.7 0.2 0.1 262.5 0.7 1.2 16.6 5.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 101.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 193.0 0.0 201.3 0.0 0.0 257.2 4.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 32.7 33.3 0.0 0.2 0.0 0.0 1.4 0.6 0.1 120.2 0.5 162.9 1.1 90.4 175.8 0.5 0.2 91.2 108.3 2.4 162.2 1.2 0.8 125.3 91.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 1.1 3.2 4.7 0.0 3.0 1.5 0.1 0.0 0.0 0.0 0.7 0.8 0.2 1.5 0.0 0.0 0.0 0.1 77.6 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.0 7.4 0.1 0.0 0.0 2.0 1.1 0.2 3.8 0.0 3.6 0.9 0.1 0.0 0.0 0.0 0.0 5.6 4.4 0.0 0.0 4.3 5.4 0.0 2.3 0.0 138.0 0.5 0.2 0.0 0.0 0.0 14.1 0.2 0.0 0.5 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.2 1.0 0.1 108.9 0.0 0.0 0.0 SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 117.9;Pancreatic endocrine cells: 81.3;Urothelial cells: 87.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 43.2;HaCaT: 34.2;HBEC3-KT: 67.4" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" 0.9 0.4 0.2 4.6 0.2 3.4 7.5 0.1 0.6 8.0 0.5 12.8 14.3 1.2 1.0 32.5 4.3 3.5 0.6 0.1 0.1 19.6 2.6 10.8 5.2 0.4 0.2 0.8 19.7 5.9 2.8 5.9 0.2 18.1 5.4 0.9 18.7 4.1 1.5 27.6 14.4 0.3 0.2 5.7 14.2 4.4 0.3 3.3 13.0 0.0 4.1 9.1 17.0 0.5 43.2 6.2 0.1 0.2 0.0 0.0 22.6 0.3 0.0 0.0 0.0 20.3 30.8 6.6 19.6 0.0 0.0 34.2 2.3 67.4 0.0 3.6 6.6 0.3 6.9 2.6 0.1 0.6 8.6 0.0 30.3 0.0 5.9 0.8 0.0 14.8 7.3 14.3 0.0 15.3 3.2 0.2 1.6 21.5 12.0 1.2 0.1 24.8 11.5 31.4 0.0 0.2 2.3 31.7 0.1 1.0 22.0 0.4 0.7 0.7 2.2 0.5 0.4 14.1 15.8 9.2 0.2 4.8 0.3 0.1 0.0 0.0 2.6 0.1 4.2 3.6 5.9 5.2 0.1 5.6 7.7 4.2 0.1 1.8 0.1 0.4 3.2 0.9 0.2 0.2 0.1 0.6 0.1 0.1 0.4 0.2 0.2 0.2 0.3 0.5 0.7 19.2 14.2 0.3 25.8 30.7 117.9 51.4 25.0 4.1 13.6 11.4 1.9 40.0 43.9 40.5 10.4 23.8 7.7 46.6 1.9 54.1 1.6 15.4 2.9 2.8 12.1 7.8 0.1 37.1 52.8 2.6 50.0 24.9 5.7 0.3 1.8 2.9 3.6 0.0 0.2 37.9 28.5 0.6 10.3 0.8 0.6 2.2 3.6 0.0 4.2 0.8 14.4 0.0 0.1 81.3 69.7 0.0 8.0 58.6 53.9 13.1 27.0 4.6 0.0 2.2 3.5 8.7 11.4 17.6 39.9 10.8 18.0 1.1 32.0 87.9 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SH3BP5 Sab ENSG00000131370 "SH3 domain binding protein 5" O60239 3 15254353-15341368 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 200.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.9;Early spermatids: 192.2;Extravillous trophoblasts: 356.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 349.3;MCF7: 118.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036445, HPA057988" Uncertain Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear bodies" "HPA036445: AB_10670106, HPA057988: AB_2683572" "unprognostic (1.28e-3)" "unprognostic (2.99e-2)" "unprognostic (9.50e-2)" "unprognostic (6.97e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (7.74e-2)" "unprognostic (7.81e-3)" "unprognostic (4.80e-2)" "unprognostic (4.09e-2)" "unprognostic (2.76e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.17e-4)" "unprognostic (4.76e-2)" "unprognostic (3.06e-2)" "unprognostic (4.34e-2)" "unprognostic (2.03e-1)" 78.3 200.5 21.2 35.2 22.7 72.6 72.0 38.4 26.1 71.1 16.0 27.4 15.7 77.5 13.5 26.9 85.6 45.7 24.1 23.3 21.0 52.8 17.3 73.2 59.9 21.4 20.0 116.2 15.9 47.9 35.7 40.8 22.4 25.0 8.4 27.4 49.9 34.1 71.7 25.6 27.0 37.3 20.8 30.9 16.1 30.9 20.9 37.4 51.1 19.1 35.7 33.0 50.6 35.1 27.4 16.5 6.4 14.1 53.1 46.8 349.3 13.6 10.9 9.3 10.4 10.8 13.4 21.3 6.2 40.8 16.1 3.6 2.9 14.2 5.9 19.5 12.8 15.7 72.3 1.9 21.9 4.4 8.6 36.9 9.3 41.6 7.9 34.2 116.0 31.3 18.4 8.5 10.3 118.1 57.6 23.2 13.6 3.5 20.6 1.1 27.2 115.6 8.8 53.5 16.8 7.8 18.6 19.2 21.7 21.6 18.1 10.9 84.3 22.8 29.5 21.9 12.0 3.3 7.6 15.2 44.7 16.3 31.5 8.1 7.8 9.1 52.9 2.5 15.9 19.1 24.1 36.1 8.9 24.3 12.9 16.6 13.9 25.4 4.6 3.9 11.1 20.4 21.2 22.7 38.4 26.1 23.3 21.0 21.4 20.0 22.4 20.8 20.9 35.1 195.9 0.0 16.3 2.3 115.2 17.0 6.0 8.2 11.4 41.3 23.5 32.1 0.7 5.7 13.9 68.0 14.6 12.5 73.7 0.6 3.9 2.7 192.2 13.1 33.0 150.7 2.4 7.0 49.5 8.7 356.3 97.5 3.6 13.7 2.5 28.1 165.0 7.0 33.1 65.6 38.4 2.5 12.2 87.2 133.3 97.8 49.0 113.1 33.8 26.2 33.3 5.1 167.9 12.5 60.6 3.2 1.1 118.5 67.1 8.5 4.7 36.2 7.5 44.4 6.6 56.8 13.4 3.0 4.5 14.2 12.1 173.2 51.5 81.6 1.4 10.2 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 360.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 190.3;ASC TERT1: 161.0;HSkMC: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 70.8 15.7 9.8 12.8 14.9 0.2 31.5 6.0 9.6 22.5 104.9 44.2 44.4 23.2 10.7 40.8 23.7 63.7 64.1 6.8 11.6 27.2 49.9 36.2 5.1 8.8 10.3 42.9 15.2 19.9 5.0 27.9 8.8 27.1 48.3 12.8 17.3 40.5 17.7 30.0 49.0 41.4 5.1 7.4 22.6 12.4 11.5 3.9 25.1 33.8 7.9 33.3 20.6 18.6 26.3 19.2 12.1 9.5 190.3 161.0 26.0 31.8 34.0 13.9 14.4 24.9 31.6 0.0 12.5 29.9 22.7 19.2 12.8 36.6 13.5 0.1 10.1 0.0 22.2 26.7 46.0 0.1 0.1 129.1 27.6 20.9 32.0 23.9 81.9 0.0 0.0 0.1 36.9 10.9 0.0 0.4 24.3 40.3 27.6 0.0 0.9 0.4 17.3 18.3 0.9 16.3 22.7 23.0 18.5 24.7 7.5 0.1 59.9 43.6 15.6 19.5 12.9 0.1 0.0 0.1 22.6 0.1 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.8 14.9 6.0 9.6 6.8 11.6 8.8 10.3 8.8 5.1 11.5 18.6 36.7 22.4 32.5 8.1 2.9 28.6 14.1 12.3 18.8 6.6 20.5 25.0 88.5 34.3 29.2 16.5 14.6 25.9 5.0 103.5 5.9 11.9 4.4 17.6 38.1 29.1 18.6 7.0 55.8 15.4 20.7 77.9 38.7 13.7 21.5 37.5 21.8 46.4 7.4 6.7 30.0 35.6 10.2 4.6 20.2 6.7 62.1 4.8 26.6 74.0 1.2 20.8 5.2 263.9 360.1 21.3 55.9 48.2 3.2 41.5 88.2 27.2 52.4 11.0 13.1 46.0 26.3 2.9 6.0 16.7 38.5 27.2 5.5 20.3 54.0 41.2 SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.8;monocytes: 289.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" 45.1 11.0 17.1 45.5 16.8 68.6 26.6 14.2 20.3 18.2 47.3 37.1 13.7 10.6 11.3 8.5 11.9 21.2 24.4 16.4 20.8 13.5 15.6 26.0 68.1 19.9 22.9 8.7 6.9 14.4 11.9 32.5 20.3 6.7 35.3 5.1 10.4 7.4 13.0 24.0 18.4 14.8 18.5 37.0 18.9 5.7 26.0 55.0 20.5 32.4 68.7 17.7 11.2 27.1 52.5 54.3 8.4 19.4 41.6 80.0 44.2 46.4 67.4 23.3 37.2 37.2 105.6 97.4 47.6 67.5 67.0 5.9 19.8 18.4 37.3 32.3 13.4 21.2 13.6 30.1 27.2 134.0 160.2 47.4 18.0 48.5 141.9 64.6 35.4 67.6 8.0 114.2 59.7 23.5 80.4 135.4 14.8 63.1 71.2 49.1 82.0 9.1 27.1 10.6 6.0 6.2 43.2 5.6 65.3 53.8 5.4 155.2 113.6 40.6 34.9 52.2 51.9 165.6 119.0 86.0 86.5 109.4 183.5 49.2 104.7 171.1 180.2 77.7 140.4 55.4 174.2 187.8 132.6 50.3 143.3 142.5 210.0 76.5 96.9 148.4 224.1 195.9 17.1 16.8 14.2 20.3 16.4 20.8 19.9 22.9 20.3 18.5 26.0 27.1 40.3 16.0 54.4 5.5 75.6 12.0 3.5 7.5 5.2 5.1 5.4 6.2 78.1 11.5 25.0 9.2 16.7 26.2 174.3 207.8 1.9 8.3 0.7 6.3 28.5 26.5 50.8 23.3 72.3 18.9 39.3 56.9 23.4 8.3 96.6 5.9 27.8 17.6 55.8 8.4 126.3 34.4 10.2 87.4 102.1 1.9 52.8 113.0 33.8 108.7 289.2 0.1 175.1 87.0 145.9 48.0 153.3 38.4 63.5 3.5 26.4 40.3 20.1 2.8 59.2 12.1 72.2 24.3 22.7 1.9 10.9 22.6 138.7 26.7 59.4 7.7 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 47.0;Excitatory neurons: 108.3;Inhibitory neurons: 160.9;Microglial cells: 164.9;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 19.8;RPMI-8226: 20.5;TIME: 23.2;U-266/84: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 6.1 6.7 4.7 3.0 6.1 0.8 4.3 1.3 6.5 5.5 1.6 5.6 1.1 3.7 0.7 2.8 4.8 4.4 6.0 6.3 3.2 6.8 1.1 7.2 2.1 3.0 4.5 3.2 2.0 0.5 1.9 5.2 2.8 4.7 1.4 0.6 1.6 4.4 5.7 3.1 3.3 3.8 3.1 2.1 2.9 4.2 3.9 3.2 2.5 7.3 1.2 5.5 4.2 3.5 0.0 0.1 0.1 2.2 9.0 6.9 0.0 4.2 12.2 3.1 1.1 1.1 0.0 0.0 3.1 3.1 0.7 0.0 0.2 1.8 1.3 0.0 4.2 0.0 0.2 0.0 19.8 0.1 0.0 12.0 2.9 14.1 6.3 1.8 11.4 2.2 0.0 11.7 7.3 0.0 0.0 6.5 1.1 0.0 12.0 2.6 0.0 20.5 0.0 0.0 0.7 2.5 0.0 0.0 0.4 0.1 0.2 0.0 23.2 4.0 12.0 11.5 5.5 4.0 28.6 0.0 0.0 6.3 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.7 6.1 1.3 6.5 6.3 3.2 3.0 4.5 2.8 3.1 3.9 3.5 5.3 0.0 0.0 47.0 0.2 1.9 0.4 0.2 1.8 0.5 0.6 0.5 10.7 0.0 0.7 0.0 0.0 0.0 1.5 0.1 0.0 1.1 2.6 9.4 9.6 6.7 1.8 0.0 108.3 0.2 0.2 4.8 0.0 1.1 0.0 0.2 7.5 0.0 4.7 10.1 160.9 0.8 0.0 2.5 1.5 5.2 2.1 1.2 5.4 164.9 0.0 1.7 0.0 42.3 1.9 0.1 0.0 3.0 1.6 0.2 0.0 0.6 2.1 0.0 13.1 3.2 6.8 0.7 9.6 0.8 0.9 0.1 0.5 2.3 0.1 0.0 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHC3 "N-Shc, NSHC, SHCC" ENSG00000148082 "SHC adaptor protein 3" Q92529 9 89005771-89178818 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1" "Group enriched" "Detected in some" 10 "Excitatory neurons: 155.2;Inhibitory neurons: 179.2;Oligodendrocyte precursor cells: 333.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.1" "Group enriched" "Detected in many" 9 "amygdala: 16.8;basal ganglia: 24.9;cerebral cortex: 28.1;hippocampal formation: 23.6;white matter: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 20.7;hTERT-RPE1: 22.6;RT4: 7.9;SH-SY5Y: 7.6;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031427, HPA046656, HPA072448" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA031427: AB_2673877, HPA046656: AB_2679740, HPA072448: AB_2686521" "unprognostic (6.22e-2)" "unprognostic (5.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-4)" "unprognostic (2.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (2.72e-3)" "unprognostic (7.39e-2)" "unprognostic (1.53e-7)" "unprognostic (8.33e-2)" "unprognostic (1.05e-1)" "unprognostic (9.01e-2)" "unprognostic (9.84e-4)" 1.0 9.0 16.8 0.2 24.9 0.0 1.7 0.0 28.1 5.8 0.0 1.4 0.4 1.7 0.9 1.0 1.7 1.8 1.1 23.6 0.0 1.4 0.2 4.6 0.2 0.0 0.0 0.2 4.0 2.7 1.1 0.2 0.0 1.0 0.7 2.3 5.0 0.6 0.3 1.8 0.7 1.0 0.0 0.1 0.8 0.3 2.3 0.0 0.6 0.6 0.2 1.4 2.9 11.4 1.4 0.4 20.7 0.0 4.5 1.4 0.0 1.5 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.0 3.1 0.0 2.1 0.0 22.6 5.5 0.1 0.0 0.0 0.0 0.2 0.0 1.3 2.7 0.3 0.3 0.3 0.0 4.5 4.5 7.9 2.8 7.6 0.5 0.0 0.0 0.2 0.0 0.4 3.2 0.8 0.1 1.3 0.1 0.0 0.0 0.0 11.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 24.9 0.0 28.1 23.6 0.0 0.0 0.0 0.0 0.0 2.3 11.4 0.3 0.0 21.0 17.6 0.0 0.1 0.3 0.1 1.2 7.6 1.1 1.0 1.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 1.9 0.1 1.1 0.4 1.8 0.5 0.0 0.0 155.2 0.9 0.1 4.4 0.0 0.2 0.0 0.3 0.0 0.0 0.2 3.3 179.2 0.0 0.0 0.0 1.1 1.6 1.5 0.3 1.8 15.0 0.0 7.2 0.0 333.8 9.6 0.1 0.0 3.8 0.0 0.0 0.1 0.6 0.9 0.6 0.0 0.9 0.9 0.3 0.6 0.7 0.6 0.4 0.3 0.8 0.0 0.8 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SHISA9 ENSG00000237515 "Shisa family member 9" B4DS77 16 12901598-13240416 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.8" "Group enriched" "Detected in many" 17 "Excitatory neurons: 265.0;Inhibitory neurons: 427.9;Oligodendrocyte precursor cells: 636.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 48.5;LHCN-M2: 40.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072399 Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "HPA072399: AB_2686517" "unprognostic (1.88e-2)" "unprognostic (3.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.69e-5)" "unprognostic (2.23e-2)" "unprognostic (2.03e-2)" "unprognostic (5.90e-5)" "unprognostic (1.50e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.53e-4)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (6.66e-2)" "unprognostic (1.26e-2)" 0.5 2.8 12.5 0.8 12.7 1.3 0.6 0.0 14.8 0.3 0.0 3.2 0.8 0.4 1.1 0.5 0.2 0.4 0.6 10.9 6.3 1.9 0.6 0.2 0.4 6.9 5.9 0.4 0.6 0.1 0.9 0.4 6.2 4.2 0.9 3.7 0.9 0.7 1.5 0.9 0.9 0.6 1.7 0.4 0.5 0.7 11.0 0.1 2.1 0.0 0.3 0.2 0.2 4.2 0.8 0.4 0.6 0.5 0.2 0.2 0.5 0.4 0.0 0.0 0.0 0.3 0.5 0.5 48.5 0.1 0.7 0.6 0.1 0.2 0.1 0.6 0.2 0.6 0.9 0.3 0.1 0.6 0.6 1.5 0.1 0.1 3.3 0.4 0.1 0.6 0.4 1.0 40.5 5.5 0.4 0.7 10.2 0.7 0.5 0.6 0.4 0.3 10.9 1.5 10.1 0.5 0.4 1.4 0.4 4.4 0.9 0.4 0.4 0.6 5.8 0.6 0.4 0.9 1.0 0.5 0.4 0.3 1.0 0.8 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 12.5 12.7 0.0 14.8 10.9 6.3 6.9 5.9 6.2 1.7 11.0 4.2 0.0 25.6 20.1 5.2 0.1 0.1 0.5 0.2 0.0 0.8 1.7 0.8 1.3 1.5 7.0 1.8 0.0 0.1 0.0 0.3 1.9 1.4 4.8 0.1 0.5 1.1 0.0 0.0 265.0 0.0 0.0 2.0 0.0 0.3 11.4 0.0 0.0 0.0 0.0 0.0 427.9 0.3 0.0 0.0 0.4 3.4 0.3 1.0 0.0 5.6 0.0 0.5 0.0 636.3 4.9 0.1 2.3 0.0 0.0 1.8 0.0 1.3 11.8 0.3 0.0 6.6 0.2 0.5 2.0 0.0 0.1 0.1 1.3 0.0 0.8 0.6 SHISAL2A "FAM159A, MGC52498" ENSG00000182183 "Shisa like 2A" Q6UWV7 1 52633168-52669683 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;intestine: 3.7;lymphoid tissue: 5.6" "Cell type enhanced" "Detected in some" "B-cells: 4.3;dendritic cells: 9.8;Endometrial stromal cells: 2.6;Hofbauer cells: 1.8;Macrophages: 2.2;T-cells: 6.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "hypothalamus: 8.7" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 10.1;NK-cells: 5.9;T-cells: 7.0" "Cell line enhanced" "Detected in some" "Daudi: 4.1;Karpas-707: 9.4;NB-4: 2.9;RPMI-8226: 13.0" "Region enhanced" "Detected in some" "hypothalamus: 4.0" "Low region specificity" "Detected in some" HPA030744 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA030744: AB_10963060" "unprognostic (7.94e-6)" "unprognostic (8.50e-3)" "unprognostic (8.29e-3)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (9.67e-4)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (2.22e-2)" "unprognostic (4.45e-2)" "unprognostic (2.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-3)" "unprognostic (7.27e-2)" "unprognostic (2.79e-1)" "unprognostic (6.50e-2)" "unprognostic (2.64e-2)" 0.4 0.2 0.8 2.3 0.7 1.7 0.2 0.8 1.0 1.0 0.4 0.4 0.3 0.4 0.7 0.2 0.6 0.3 0.1 0.5 8.7 0.3 0.2 0.7 5.6 1.0 1.6 0.0 0.2 0.0 2.0 0.1 1.1 0.4 0.3 0.1 0.3 0.3 0.3 0.0 3.7 0.0 0.9 5.4 0.5 0.8 2.5 1.0 0.7 0.2 5.2 0.3 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 2.9 1.6 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.0 0.0 3.9 10.1 6.2 5.6 0.0 9.8 4.3 2.6 0.0 5.9 0.0 0.0 2.1 1.6 0.8 0.7 0.8 1.0 0.5 8.7 1.0 1.6 1.1 0.9 2.5 1.2 0.6 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.6 2.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 6.4 0.5 0.0 0.0 SHLD3 "AC008560.1, CTC-534A2.2, FLJ26957, RINN1" ENSG00000253251 "Shieldin complex subunit 3" Q6ZNX1 5 65625027-65630928 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 17.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.0;dendritic cells: 5.9;Distal tubular cells: 3.9;Pancreatic endocrine cells: 4.6;Proximal tubular cells: 5.3;Syncytiotrophoblasts: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066071, HPA068764" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 34: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA066071: AB_2685609, HPA068764: AB_2686028" "unprognostic (7.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (9.52e-2)" "unprognostic (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.38e-2)" "unprognostic (7.24e-3)" "unprognostic (5.09e-4)" "unprognostic (2.12e-2)" "unprognostic (1.68e-2)" "unprognostic (1.49e-1)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "prognostic favorable (1.17e-4)" 2.3 2.7 2.4 2.7 2.5 17.5 4.2 2.8 3.6 1.8 1.8 2.8 2.8 2.3 3.1 1.5 1.9 2.4 1.8 2.3 2.1 2.9 2.6 2.5 4.8 2.4 2.1 1.5 3.4 2.1 2.5 2.5 2.3 4.3 3.0 3.7 2.0 2.5 1.8 2.9 2.7 1.7 2.4 2.5 2.4 3.2 2.4 3.9 2.4 1.9 3.6 2.5 1.3 3.2 2.6 3.6 5.0 10.8 2.9 3.5 6.3 3.8 3.5 5.8 7.0 5.9 8.0 4.9 4.2 4.6 6.5 3.1 5.1 4.7 8.5 6.7 6.5 4.3 10.3 8.3 2.5 5.0 7.5 2.1 6.8 6.0 6.1 1.6 3.7 7.7 6.4 11.5 4.7 6.9 6.7 7.7 4.0 1.5 2.2 4.4 4.9 7.9 4.9 6.0 6.7 5.5 3.2 3.3 11.0 3.4 3.8 4.6 3.0 5.0 6.8 4.1 6.6 7.2 14.3 10.7 3.7 6.1 4.7 15.9 3.0 6.4 3.8 2.9 4.0 3.9 4.5 4.0 2.8 3.1 6.1 5.6 3.3 4.9 3.1 3.2 6.2 2.1 2.4 2.5 2.8 3.6 2.3 2.1 2.4 2.1 2.3 2.4 2.4 3.2 3.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.8 3.6 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 3.9 3.1 0.0 1.9 1.8 0.8 0.0 0.0 0.0 2.9 3.8 0.9 0.0 2.1 0.0 2.1 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.1 1.8 2.1 0.0 0.0 SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Cone photoreceptor cells: 47.9;Microglial cells: 24.4;Peritubular cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 19.2;SK-MEL-30: 18.2;SuSa: 18.6;WM-115: 23.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051646 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: AB_2681562" "unprognostic (8.65e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (6.99e-3)" "unprognostic (8.05e-2)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (9.73e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (1.93e-1)" "unprognostic (7.67e-3)" 0.7 1.8 4.3 0.4 6.0 0.0 1.0 3.6 10.1 2.4 5.4 1.5 0.7 1.5 2.7 5.0 1.6 3.1 0.7 5.9 4.0 3.7 4.0 4.1 0.3 4.8 5.0 6.9 3.7 2.4 4.4 7.6 4.3 5.3 1.3 20.8 3.2 2.6 0.1 4.1 0.5 0.8 4.3 0.7 1.5 3.4 4.7 3.6 1.4 0.1 1.3 2.4 3.1 5.2 6.2 0.7 11.0 1.5 0.6 1.7 6.2 0.6 2.0 2.4 3.8 7.5 0.1 0.0 2.0 1.6 0.4 4.8 5.7 15.9 2.8 0.0 4.3 0.0 0.0 1.2 3.5 0.0 7.4 0.3 10.9 18.0 0.7 3.9 13.7 0.0 0.0 0.0 3.9 6.5 0.0 0.1 9.7 0.0 0.0 0.0 12.1 0.0 10.2 19.2 1.6 0.9 0.5 0.1 18.2 18.6 6.5 0.4 6.4 17.3 2.2 0.1 0.6 0.0 0.0 0.0 11.4 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 6.0 3.6 10.1 5.9 4.0 4.8 5.0 4.3 4.3 4.7 5.2 1.1 0.0 1.5 26.4 0.0 1.9 3.3 2.8 10.8 9.5 3.4 1.7 4.1 4.3 3.1 3.7 47.9 8.9 0.0 2.0 3.9 3.0 0.5 4.8 2.5 7.2 1.2 2.7 9.5 0.0 1.3 1.5 3.1 5.9 0.0 5.4 10.0 5.7 0.7 1.7 9.5 0.3 4.1 0.8 0.0 1.0 3.7 0.2 0.0 24.4 0.0 2.4 0.0 9.5 4.6 1.6 0.1 83.1 0.0 5.4 0.1 1.0 2.8 18.0 0.0 0.6 1.8 0.1 1.1 10.8 2.0 2.1 0.5 5.5 0.9 5.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178736-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 83.5;non-classical monocyte: 151.0" "Lineage enriched" "Detected in all" 7 "monocytes: 151.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "HPA052352: AB_2681797" "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" "unprognostic (9.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (2.67e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (4.18e-5)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (5.22e-3)" 40.2 25.1 23.5 21.2 28.4 12.4 36.3 27.4 27.1 32.8 19.4 28.8 44.2 30.5 16.0 15.1 31.3 18.5 31.8 24.1 23.2 20.6 40.8 36.4 23.4 37.0 29.2 60.2 113.4 13.6 35.7 22.4 33.9 48.6 23.1 14.4 31.5 21.2 25.2 32.7 42.3 20.8 29.7 34.6 75.9 28.5 29.2 10.0 31.7 12.3 20.4 26.2 20.4 48.9 8.7 8.8 10.5 15.4 34.4 30.7 34.8 14.8 19.5 9.3 8.6 25.1 32.8 8.9 23.1 39.1 11.7 9.0 10.2 11.5 7.6 13.2 12.4 6.3 15.8 17.3 17.8 5.3 15.5 38.1 12.8 12.0 12.9 28.6 19.1 11.4 12.0 19.2 22.1 18.2 7.5 6.2 4.9 45.6 6.5 5.6 7.2 25.5 12.2 9.1 3.2 7.9 15.8 38.1 2.6 11.7 30.8 6.3 11.9 12.3 7.9 8.2 3.4 13.6 5.3 9.4 7.1 10.8 9.2 0.3 14.2 0.5 1.9 83.5 1.5 18.3 1.1 1.3 11.5 21.2 1.7 1.3 1.7 1.5 151.0 6.2 1.4 9.6 23.5 28.4 27.4 27.1 24.1 23.2 37.0 29.2 33.9 29.7 29.2 48.9 12.2 6.4 12.3 11.8 24.1 67.7 25.4 4.1 4.0 13.0 11.1 13.0 7.9 4.3 4.5 11.0 6.2 9.2 6.7 16.7 0.0 4.4 7.4 11.6 22.2 12.7 11.4 8.2 7.7 9.6 33.4 19.7 61.2 11.2 2.5 43.5 16.4 25.6 16.9 18.5 8.8 32.9 2.0 54.2 29.3 11.5 13.4 30.6 19.6 7.5 13.6 6.1 7.2 12.1 16.8 8.0 9.4 13.5 6.6 20.5 40.7 1.8 6.0 12.1 19.7 46.1 18.7 5.8 4.8 4.2 42.9 32.3 9.5 38.2 13.5 15.5 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SIRPG "bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma" ENSG00000089012 "Signal regulatory protein gamma" Q9P1W8 20 1629152-1657779 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 39.1" "Group enriched" "Detected in some" 8 "Early spermatids: 48.9;Late spermatids: 14.1;T-cells: 41.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 369.4" "Lineage enriched" "Detected in many" 6 "T-cells: 369.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.8;JURKAT: 10.7;NB-4: 13.8;RT4: 3.6;THP-1: 2.3" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.35e-3)" "unprognostic (4.09e-3)" "unprognostic (7.32e-3)" "prognostic favorable (1.05e-6)" "unprognostic (4.23e-3)" "prognostic favorable (2.24e-4)" "unprognostic (4.49e-2)" "unprognostic (1.30e-2)" "prognostic favorable (7.36e-7)" "unprognostic (1.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.40e-2)" "unprognostic (2.95e-3)" 0.4 0.7 0.0 12.9 0.0 2.9 0.9 0.0 0.2 1.0 0.0 2.5 1.8 0.4 0.2 1.1 0.4 2.3 0.6 0.0 0.0 0.3 1.0 1.5 34.3 0.2 0.0 0.3 0.2 0.0 0.1 0.2 0.1 0.7 3.0 0.0 1.2 0.6 0.0 0.3 5.8 0.7 0.1 9.4 3.0 0.3 0.0 39.1 0.7 0.1 28.1 3.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 4.8 0.0 10.7 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.9 1.5 1.2 67.6 0.7 186.4 0.7 207.6 157.7 0.9 0.7 215.8 176.2 6.0 59.1 1.1 6.7 369.4 101.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 1.3 1.4 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 48.9 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.2 0.5 0.1 1.3 0.0 0.4 0.2 0.0 0.0 0.4 0.2 0.0 1.0 0.4 14.1 0.3 0.7 0.0 1.0 1.4 0.0 2.1 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 41.3 0.0 0.0 0.0 SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650950 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 95.4" "Cell type enhanced" "Detected in some" "B-cells: 78.9;dendritic cells: 31.2;Plasma cells: 19.8;T-cells: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 202.7;memory B-cell: 213.6;memory CD4 T-cell: 249.2;memory CD8 T-cell: 223.4;naive B-cell: 192.1;naive CD4 T-cell: 170.4;naive CD8 T-cell: 169.5;plasmacytoid DC: 203.1;T-reg: 352.4" "Group enriched" "Detected in many" 56 "B-cells: 213.6;dendritic cells: 203.1;T-cells: 352.4" "Group enriched" "Detected in some" 5 "Daudi: 113.1;HDLM-2: 70.6;JURKAT: 58.7;U-698: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018506 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018506: AB_2669896" "unprognostic (4.28e-3)" "prognostic favorable (6.56e-4)" "unprognostic (8.01e-3)" "prognostic favorable (1.94e-6)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-4)" "unprognostic (1.75e-2)" "unprognostic (9.34e-3)" "prognostic favorable (8.17e-4)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (8.87e-2)" "unprognostic (6.34e-2)" 0.9 0.7 0.1 19.1 0.1 1.9 0.9 0.0 0.2 0.5 0.1 2.4 2.9 0.5 1.1 0.8 0.5 1.7 0.5 0.1 0.1 0.7 0.7 2.8 50.6 0.3 0.1 0.5 0.2 0.1 0.1 0.2 0.3 0.6 2.2 0.0 2.6 0.3 0.3 0.7 13.2 0.6 0.1 23.6 4.7 0.2 0.6 95.4 0.8 0.1 32.5 3.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.7 0.1 0.0 0.0 0.0 19.1 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.1 0.0 0.0 104.4 0.0 0.0 0.0 1.4 1.3 0.7 119.1 0.8 202.7 213.6 249.2 223.4 1.8 192.1 170.4 169.5 4.5 0.8 0.8 203.1 352.4 123.9 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.2 0.9 0.0 0.0 0.0 78.9 5.6 0.0 0.0 1.2 0.0 1.0 1.0 0.2 1.5 0.0 0.0 0.0 0.0 31.2 0.7 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.7 0.0 0.0 1.9 0.9 2.0 0.0 0.0 0.0 1.4 0.2 5.3 0.0 0.0 0.0 0.0 2.7 7.4 0.0 0.0 3.4 5.4 0.0 2.5 0.0 4.1 0.0 0.0 0.1 0.1 0.0 19.8 0.0 0.0 0.3 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.5 3.7 0.3 86.8 0.0 0.3 0.0 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 22.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Excitatory neurons: 38.4;granulocytes: 17.8;Inhibitory neurons: 27.8;Intestinal goblet cells: 36.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.6;HHSteC: 33.6;OE19: 27.6;U-2197: 67.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA031123: AB_2301872" "unprognostic (4.74e-2)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (5.91e-3)" "unprognostic (7.35e-3)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.13e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (7.18e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-2)" 1.5 1.1 2.9 1.2 3.2 0.0 2.3 1.0 3.1 1.4 11.7 3.5 5.6 0.6 3.6 4.1 2.0 8.3 0.6 3.4 2.4 3.2 6.8 2.2 0.6 1.6 2.0 0.3 10.0 4.3 2.2 2.7 1.9 2.8 4.2 0.1 11.9 0.6 0.1 1.3 3.6 0.7 1.0 0.3 4.1 2.3 2.0 0.5 22.9 0.0 0.9 2.1 2.2 2.0 14.7 0.0 2.7 0.0 3.3 4.6 6.7 0.8 2.0 0.9 1.7 19.6 6.8 0.0 1.9 5.6 2.8 8.5 0.0 0.0 0.5 0.0 0.0 0.0 7.2 0.0 33.6 0.0 1.0 8.7 8.3 1.9 0.9 16.3 0.0 0.0 0.0 0.6 1.3 3.9 0.0 0.0 9.3 27.6 0.7 0.0 0.2 0.0 6.8 1.3 4.2 0.0 7.0 8.4 0.1 0.9 15.6 0.4 0.2 0.2 1.3 67.9 0.0 0.1 1.9 5.0 3.3 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.2 1.0 3.1 3.4 2.4 1.6 2.0 1.9 1.0 2.0 2.0 0.2 0.0 0.5 7.2 0.1 1.0 1.3 3.3 3.4 0.0 5.6 4.3 1.1 2.8 2.5 23.9 0.0 0.5 0.1 1.6 0.0 3.9 0.3 0.8 1.4 0.3 5.4 0.0 38.4 3.5 6.5 2.1 7.7 2.7 17.8 1.8 0.0 9.4 0.9 0.0 27.8 36.6 0.0 0.0 0.7 0.5 0.0 0.5 0.0 7.5 2.1 0.0 1.0 31.7 2.0 2.9 3.4 0.0 0.2 6.2 2.6 1.5 0.4 0.0 0.0 0.2 0.7 0.6 0.4 4.3 0.3 3.0 0.8 0.1 5.6 1.0 SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 119.6;kidney: 38.2;salivary gland: 44.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 290.2;Proximal tubular cells: 97.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014963 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.7 6.1 119.6 0.0 3.0 0.0 0.0 6.8 0.0 0.0 0.0 38.2 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.8 44.9 11.4 0.0 3.1 90.8 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 13.7 10.9 0.6 27.1 1.6 3.7 12.5 0.0 0.7 29.3 9.8 0.7 0.0 0.0 0.0 0.2 4.8 0.0 0.1 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 31.4 0.0 0.0 0.4 0.0 0.0 0.7 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 15.7 0.0 0.0 0.0 290.2 97.8 0.3 0.4 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 25.8 0.5 SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 407.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.8;Cytotrophoblasts: 106.6;Excitatory neurons: 65.0;Oligodendrocytes: 178.1;Proximal tubular cells: 245.9;Syncytiotrophoblasts: 79.4" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.1;EFO-21: 18.8;Hep G2: 56.1;HHSteC: 18.4;K-562: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" 1.3 2.4 12.5 0.7 22.8 0.2 1.9 16.5 16.1 2.0 4.9 0.8 0.3 1.8 1.0 0.9 2.4 1.9 1.0 10.1 16.2 407.6 21.7 1.4 0.6 18.3 19.5 4.5 9.0 0.2 2.6 43.2 19.0 6.3 0.5 1.1 4.9 0.8 1.0 2.2 0.4 1.9 12.5 0.6 4.7 8.7 19.9 1.1 1.4 0.3 0.7 1.8 1.4 37.4 0.1 0.0 1.6 5.6 8.3 7.7 16.1 3.5 2.0 1.9 1.4 0.0 0.1 0.2 18.8 0.2 0.1 2.1 0.1 2.6 4.5 0.0 0.6 6.8 0.4 56.1 18.4 0.1 4.8 10.5 7.5 10.9 5.4 5.4 0.0 0.0 15.3 0.3 0.0 0.6 0.1 0.7 10.3 0.2 0.0 0.2 0.0 0.1 1.2 0.4 0.7 0.2 0.0 4.0 0.8 1.0 2.9 0.3 0.2 0.1 4.0 8.7 0.1 0.5 1.2 0.1 0.6 0.0 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.0 12.5 22.8 16.5 16.1 10.1 16.2 18.3 19.5 19.0 12.5 19.9 37.4 0.3 0.0 2.2 53.8 3.8 1.3 1.0 0.8 6.2 0.7 1.2 1.7 1.7 0.0 0.5 7.3 0.0 106.6 0.0 0.1 15.6 0.2 23.3 0.5 2.0 0.6 0.0 0.0 65.0 0.9 7.1 2.3 3.1 0.8 0.0 3.0 0.4 17.5 9.5 0.0 40.3 0.0 0.0 0.3 0.7 27.8 3.1 2.0 0.0 11.2 0.0 0.4 0.0 24.1 178.1 0.9 0.0 0.4 1.2 3.5 0.0 245.9 6.4 0.2 0.0 0.4 1.0 6.6 1.2 1.2 0.6 79.4 1.5 2.2 0.0 0.6 SLC15A1 "HPECT1, HPEPT1, PEPT1" ENSG00000088386 "Solute carrier family 15 member 1" P46059 13 98683801-98752672 "Metabolic proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 203.0" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 414.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 55.5;SK-BR-3: 54.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002827 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "HPA002827: AB_1856974" "unprognostic (8.76e-2)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (6.26e-2)" "unprognostic (7.83e-2)" "unprognostic (5.47e-2)" "unprognostic (1.92e-1)" "unprognostic (2.37e-1)" "unprognostic (6.79e-2)" "unprognostic (6.88e-4)" "unprognostic (2.11e-2)" "unprognostic (2.84e-1)" "unprognostic (2.64e-1)" "unprognostic (9.01e-2)" "unprognostic (3.87e-2)" 0.1 0.0 0.3 0.4 0.3 0.5 1.1 0.6 0.4 2.4 1.4 4.5 151.6 5.5 5.9 2.1 0.1 43.1 0.0 0.2 0.6 6.1 18.2 0.1 0.3 0.3 0.6 0.1 8.3 20.6 0.3 0.1 0.4 1.4 2.7 0.0 0.5 0.5 0.7 23.2 203.0 0.4 0.1 0.1 1.2 0.2 1.4 0.2 0.3 0.0 0.6 2.5 3.9 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 9.2 55.5 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.5 12.8 0.0 0.1 0.1 3.3 3.2 1.2 0.1 0.6 0.1 54.7 0.0 2.6 0.2 0.0 0.0 0.4 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.3 0.3 0.6 0.4 0.2 0.6 0.3 0.6 0.4 0.1 1.4 0.7 0.6 3.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 50.1 2.4 1.8 0.0 0.0 0.0 33.0 1.9 10.7 0.0 8.2 9.9 0.4 3.6 0.0 0.3 0.9 0.0 0.2 0.0 77.6 0.0 7.2 0.4 32.4 0.1 0.0 0.2 12.0 0.0 0.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.5 0.3 2.2 13.8 0.0 0.0 0.6 414.1 10.4 1.7 0.0 0.0 1.3 0.8 0.0 0.3 0.0 0.9 0.1 0.4 0.0 5.8 0.5 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Hepatocytes: 63.7;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 83.9;GAMG: 70.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" 13.8 24.7 4.6 4.8 5.8 0.0 5.4 1.7 5.7 9.4 1.2 7.0 3.3 10.3 1.7 2.9 9.3 6.0 10.4 7.7 4.9 7.9 40.7 7.5 0.9 5.6 3.9 12.8 5.5 11.7 9.8 9.2 1.8 6.2 1.8 1.1 5.0 5.8 2.7 2.5 3.1 6.9 3.5 1.2 4.7 0.9 8.1 5.7 12.6 3.7 1.8 6.6 6.2 3.0 8.4 10.4 7.2 43.1 20.8 11.1 0.0 83.9 29.7 38.2 20.6 0.1 0.9 0.0 1.3 37.5 70.8 1.7 1.1 40.2 22.1 6.1 3.6 0.0 0.0 0.0 1.5 0.0 0.0 16.5 9.5 19.3 23.3 14.6 0.1 0.1 0.0 0.0 9.1 0.0 0.5 2.7 27.2 0.0 7.8 17.4 19.9 0.0 18.0 0.1 1.9 12.0 9.6 50.2 0.3 2.5 0.6 1.1 0.0 32.5 8.8 35.7 41.9 0.0 0.0 0.0 34.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 1.7 5.7 7.7 4.9 5.6 3.9 1.8 3.5 8.1 3.0 5.6 0.0 0.6 22.2 0.2 0.8 4.3 2.4 0.6 5.7 4.3 3.4 4.5 8.6 2.9 3.7 0.0 5.7 0.1 0.0 3.9 4.3 0.1 0.3 9.8 6.1 8.4 0.0 14.5 2.4 4.9 11.8 0.5 0.5 2.5 1.7 3.6 63.7 1.0 3.3 21.6 0.3 0.0 1.3 0.8 1.2 15.2 0.1 3.6 15.9 0.6 6.2 0.0 23.1 7.1 4.6 0.0 20.7 0.1 5.1 0.4 4.7 2.4 1.5 13.1 9.7 5.6 0.1 0.1 0.9 1.3 2.1 0.4 1.4 0.2 4.9 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084093 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.1" "Cell type enhanced" "Detected in some" "Leydig cells: 4.4;Melanocytes: 5.4;Oligodendrocytes: 4.0;Spermatogonia: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;SiHa: 2.1;T-47d: 1.3;U-2 OS: 1.2;U-266/70: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" 0.5 0.3 1.1 0.0 3.3 0.2 0.6 0.2 6.0 0.7 0.0 0.3 0.1 0.4 0.0 0.3 0.9 0.1 0.6 0.8 1.1 0.4 0.2 0.3 0.0 4.0 1.4 0.3 0.4 0.0 1.6 0.0 3.6 1.7 0.0 0.1 1.2 0.0 0.5 0.7 0.2 0.0 0.3 0.3 0.4 0.8 2.8 0.0 0.7 0.0 0.0 0.4 0.7 9.1 0.3 0.0 0.1 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.4 0.1 2.1 0.0 0.2 0.1 1.3 0.0 0.0 0.0 1.2 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.3 0.2 6.0 0.8 1.1 4.0 1.4 3.6 0.3 2.8 9.1 0.6 0.0 0.0 0.7 0.0 1.3 0.5 0.6 0.6 0.1 0.6 0.8 0.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.3 0.1 0.9 0.2 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.0 1.7 0.7 0.1 1.0 0.0 0.4 0.2 0.0 0.8 1.4 2.5 4.4 0.7 5.4 0.0 0.0 1.4 0.0 0.5 4.0 0.3 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 1.5 2.4 2.1 7.7 0.5 0.9 0.0 0.3 0.6 0.1 0.7 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC22A17 "BOCT, BOIT, NGALR" ENSG00000092096 "Solute carrier family 22 member 17" Q8WUG5 14 23346306-23352912 "Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 304.0;choroid plexus: 372.6;pituitary gland: 149.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 71.4;Horizontal cells: 201.9;Inhibitory neurons: 111.1;Muller glia cells: 74.2;Oligodendrocyte precursor cells: 120.6" "Cancer enhanced" "Detected in all" "glioma: 51.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.7;AN3-CA: 31.4;ASC diff: 23.2;SH-SY5Y: 41.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002728 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA002728: AB_1079998" "unprognostic (9.34e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.23e-3)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.31e-2)" "unprognostic (1.26e-2)" "unprognostic (4.23e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.73e-4)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (3.50e-2)" "unprognostic (1.23e-2)" "unprognostic (3.87e-2)" 7.3 30.1 159.4 3.9 159.6 0.6 11.8 98.0 159.1 25.4 372.6 24.6 4.6 14.8 10.3 4.4 19.1 6.4 22.0 145.5 304.0 16.3 2.5 8.3 3.4 165.6 143.8 17.0 17.2 11.4 149.1 5.0 145.5 39.8 2.4 26.4 25.4 25.7 1.5 7.6 10.2 7.0 125.5 4.2 13.3 8.9 231.8 1.7 19.1 2.7 1.6 15.2 17.9 139.5 0.0 1.9 20.7 31.4 23.2 11.4 3.4 7.5 11.6 2.5 1.9 0.0 1.9 0.0 2.8 11.0 6.6 0.4 0.7 0.5 0.0 0.0 1.4 4.4 0.0 0.2 13.1 0.0 4.4 16.7 1.2 2.6 0.0 11.3 0.8 9.1 0.0 0.2 3.8 3.2 0.1 0.2 11.3 0.0 0.0 0.0 0.7 0.2 0.0 2.0 19.9 41.5 5.8 0.0 0.0 4.0 3.5 0.6 0.0 2.9 8.9 16.6 0.0 0.1 3.2 0.0 1.9 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 159.4 159.6 98.0 159.1 145.5 304.0 165.6 143.8 145.5 125.5 231.8 139.5 7.7 0.0 2.7 46.7 2.3 12.6 18.6 2.6 12.5 53.0 23.4 30.1 10.0 2.8 5.5 20.2 43.8 2.4 1.0 0.0 1.9 0.7 0.2 1.8 10.6 12.0 20.8 1.7 71.4 1.3 4.9 21.7 3.6 0.6 4.5 12.0 16.8 0.9 1.0 201.9 111.1 0.0 0.0 0.6 5.1 2.3 21.1 1.2 7.2 19.7 0.7 74.2 0.0 120.6 49.2 1.5 0.0 42.9 9.2 31.3 0.0 16.9 3.2 69.0 0.0 14.1 18.0 1.1 2.3 3.0 10.9 4.8 2.0 4.5 0.3 6.1 SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enhanced" "Detected in many" "Early spermatids: 86.8;Late spermatids: 229.3;Oligodendrocytes: 285.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" 7.3 3.4 17.7 4.5 28.9 9.6 8.4 25.4 25.0 9.1 1.8 18.4 20.7 4.1 12.2 23.7 11.0 4.9 3.6 16.2 18.6 7.7 18.1 8.3 4.4 29.9 29.7 4.1 15.5 27.1 8.8 8.5 30.4 18.6 14.8 4.8 14.6 2.4 8.9 17.1 22.4 2.8 22.1 6.3 26.5 11.5 30.2 7.2 5.6 7.8 5.9 4.3 15.5 50.9 4.3 10.1 20.1 22.6 7.2 7.8 26.6 0.7 0.3 1.2 0.5 22.5 0.7 1.0 2.5 4.8 18.2 6.1 4.2 10.8 0.4 3.5 13.1 10.4 3.9 18.9 1.0 0.7 0.6 2.0 21.3 19.4 1.0 4.3 0.7 5.4 9.6 5.3 0.7 5.3 1.0 2.4 7.1 23.2 3.9 2.2 1.3 18.1 0.1 26.9 2.4 0.3 5.7 7.8 7.0 20.9 31.8 0.2 5.6 12.0 4.0 15.9 2.6 12.7 0.2 0.4 21.2 0.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.2 17.7 28.9 25.4 25.0 16.2 18.6 29.9 29.7 30.4 22.1 30.2 50.9 22.6 6.4 17.5 46.7 1.0 11.6 5.0 18.7 4.6 8.0 9.5 8.1 2.8 10.0 18.0 5.5 8.4 16.1 0.5 43.3 0.0 2.9 86.8 11.6 2.5 8.2 4.2 11.0 59.9 8.0 1.3 1.9 39.8 4.1 0.0 13.1 6.4 12.7 12.9 0.0 67.4 49.7 12.2 13.0 3.0 229.3 1.8 4.8 3.6 77.8 6.4 8.6 0.0 45.8 285.5 6.1 20.5 0.7 0.4 13.9 34.3 4.2 42.0 3.5 0.0 4.5 2.6 2.5 1.2 10.3 12.6 9.2 1.3 0.1 25.3 4.5 SLC23A1 "SLC23A2, SVCT1, YSPL3" ENSG00000170482 "Solute carrier family 23 member 1" Q9UHI7 5 139367196-139384553 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "fallopian tube: 54.2;intestine: 65.3;kidney: 40.2;liver: 22.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 65.2;Hepatocytes: 19.3;Proximal enterocytes: 131.7;Proximal tubular cells: 27.0" "Group enriched" "Detected in many" 5 "endometrial cancer: 2.1;liver cancer: 7.7;prostate cancer: 4.0;renal cancer: 3.9" "Region enhanced" "Detected in some" "midbrain: 3.2" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 9.4;HDLM-2: 8.3;Hep G2: 13.6;JURKAT: 15.5;Karpas-707: 10.9;RPMI-8226: 10.9;U-266/70: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047612 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA047612: AB_2680102" "unprognostic (4.00e-3)" "unprognostic (2.66e-3)" "unprognostic (2.63e-2)" "unprognostic (1.75e-3)" "unprognostic (1.93e-1)" "unprognostic (6.36e-6)" "unprognostic (7.41e-2)" "unprognostic (6.55e-2)" "unprognostic (5.88e-2)" "unprognostic (3.90e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (4.16e-2)" "unprognostic (1.55e-2)" "unprognostic (3.65e-3)" 0.2 0.1 0.1 1.2 0.2 2.8 0.2 1.1 0.2 2.3 0.1 3.3 26.3 0.7 0.0 0.3 54.2 2.4 0.1 0.2 0.4 40.2 22.5 0.9 1.7 1.1 3.2 0.3 1.2 0.3 0.2 0.1 0.8 6.3 1.5 0.6 3.2 0.6 0.4 1.9 65.3 0.2 0.1 1.3 1.5 0.2 0.2 5.5 0.2 0.0 1.2 0.4 0.3 0.6 0.3 2.1 0.4 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.4 1.3 5.8 3.0 0.0 0.1 0.3 0.0 0.0 0.1 8.3 0.1 0.2 0.8 13.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 15.5 0.1 10.9 0.0 0.2 5.7 1.0 0.1 0.8 0.1 6.8 0.3 10.9 0.5 0.4 0.3 0.3 0.3 1.9 0.0 0.7 5.0 0.1 0.3 0.3 0.3 0.1 0.0 16.6 2.2 7.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.1 0.2 1.1 0.2 0.2 0.4 1.1 3.2 0.8 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.3 1.5 2.0 0.0 4.2 0.4 0.4 1.9 5.9 0.2 0.0 65.2 0.7 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 1.5 0.0 0.1 0.4 19.3 0.1 0.0 1.2 3.6 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.1 3.1 0.0 0.4 0.9 131.7 27.0 13.4 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 4.2 0.2 SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 9 "Astrocytes: 134.5;Inhibitory neurons: 327.0;Oligodendrocyte precursor cells: 375.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Cell line enriched" "Detected in some" 4 "HMC-1: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" 10.4 3.1 16.2 4.0 11.7 1.4 4.9 13.3 56.1 17.8 2.7 10.8 3.8 28.3 24.3 20.6 20.0 13.0 1.1 81.7 18.6 1.1 0.7 5.5 1.0 13.6 19.2 14.6 0.7 7.5 1.2 3.0 9.1 10.9 5.4 7.3 4.7 17.5 40.9 7.0 5.0 29.1 10.3 2.4 3.8 1.5 34.8 1.9 3.0 16.9 2.7 8.6 8.9 5.4 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.8 13.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 18.2 0.0 0.0 0.7 0.0 75.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 9.0 0.0 0.6 17.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.2 11.7 13.3 56.1 81.7 18.6 13.6 19.2 9.1 10.3 34.8 5.4 0.2 3.2 1.1 134.5 0.1 1.1 1.1 0.4 0.0 19.1 5.0 2.3 0.4 0.0 1.3 1.8 0.0 8.5 0.1 0.3 0.0 0.1 17.0 1.2 29.8 0.4 7.7 3.4 11.8 0.0 0.3 1.9 0.0 1.6 26.6 0.1 0.4 0.0 0.6 1.7 327.0 4.1 0.0 0.0 0.7 18.3 3.7 1.1 0.0 12.2 0.0 3.1 0.0 375.5 2.4 0.2 2.8 4.1 0.4 0.8 0.4 0.0 0.0 2.2 0.0 2.7 3.0 0.5 0.8 2.9 4.1 3.4 0.4 0.1 0.7 3.8 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 245.1;skeletal muscle: 190.8;tongue: 346.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 4722.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" 4.7 5.7 14.0 1.6 15.3 0.4 4.6 22.6 30.6 3.4 6.8 21.0 3.0 5.9 3.5 10.1 5.8 3.9 245.1 16.7 11.8 10.4 7.3 4.5 1.5 11.6 10.7 4.9 5.2 7.8 9.5 1.7 11.8 8.9 3.9 19.9 9.0 12.6 190.8 3.3 6.8 8.1 9.4 3.1 15.7 4.7 12.5 1.4 5.2 346.6 1.2 9.8 3.6 18.2 0.7 3.1 2.5 5.1 2.7 0.3 4.6 2.6 0.8 3.1 3.0 6.8 1.7 2.3 1.8 3.1 2.4 2.5 9.8 2.7 2.0 3.9 8.4 1.6 4.7 8.1 5.5 1.4 1.5 2.0 6.6 4.7 1.3 7.2 2.3 4.0 3.8 1.7 1.9 5.0 1.6 3.1 4.1 2.2 6.6 2.5 1.3 3.2 6.9 4.8 8.1 6.2 3.1 1.3 12.5 4.5 2.4 1.1 1.7 0.2 1.4 1.5 3.4 7.3 3.5 2.9 2.2 0.3 2.8 0.0 0.0 0.0 1.7 0.0 1.3 1.5 0.5 1.4 0.0 1.0 0.4 1.2 0.1 0.3 0.0 1.3 0.5 0.6 14.0 15.3 22.6 30.6 16.7 11.8 11.6 10.7 11.8 9.4 12.5 18.2 37.5 86.6 76.4 22.9 37.9 44.1 159.0 119.9 30.1 180.6 42.9 53.5 4722.0 115.8 80.0 71.7 104.3 69.2 41.1 44.4 988.0 75.3 20.6 77.8 7.4 80.1 53.8 3.0 35.1 74.1 56.5 120.1 54.0 33.6 12.0 18.6 27.5 92.1 65.9 159.9 43.7 40.6 215.7 8.5 13.8 16.7 46.6 6.8 190.3 19.7 9.0 541.2 16.5 26.7 29.2 51.4 28.5 112.8 76.4 59.1 113.8 178.3 144.0 221.0 105.2 134.5 402.7 28.0 34.0 33.2 18.2 40.5 27.7 23.7 54.2 50.7 SLC26A5 "DFNB61, PRES" ENSG00000170615 "Solute carrier family 26 member 5" P58743 7 103352730-103446207 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell shape, Hearing" "Motor protein" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Astrocytes: 5.5;Excitatory neurons: 4.1;Gastric mucus-secreting cells: 7.1;Hepatic stellate cells: 5.3;Inhibitory neurons: 3.5;Microglial cells: 6.5;Oligodendrocytes: 4.2" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "basal ganglia: 10.4" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.86e-2)" "unprognostic (5.13e-2)" "unprognostic (6.38e-3)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.56e-4)" "unprognostic (4.21e-3)" "unprognostic (8.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.97e-1)" "unprognostic (3.67e-5)" "unprognostic (3.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.94e-2)" "unprognostic (2.69e-3)" 0.1 0.1 0.3 0.0 0.3 0.0 0.7 2.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.4 0.1 0.4 0.5 0.0 0.2 0.3 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.6 0.2 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.2 0.2 0.1 0.4 0.4 0.5 0.3 0.4 0.3 0.5 0.3 6.4 2.6 5.5 0.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.2 0.5 0.0 0.0 4.1 0.0 0.0 2.2 7.1 0.2 0.0 0.0 5.3 0.0 0.0 0.0 3.5 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.0 6.5 0.0 0.3 0.0 2.0 4.2 0.3 0.0 0.0 0.0 0.8 0.0 0.0 2.2 1.2 0.0 0.2 0.1 0.3 0.5 0.0 0.3 0.0 0.6 0.0 0.0 0.6 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC2A10 GLUT10 ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 43.6;Intestinal goblet cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 75 "basophil: 20.9" "Lineage enriched" "Detected in single" 75 "granulocytes: 20.9" "Cell line enhanced" "Detected in many" "ASC diff: 45.8;HSkMC: 56.6;OE19: 49.8;SK-MEL-30: 60.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" 7.0 5.9 4.0 3.5 4.1 1.2 15.3 3.4 3.9 19.4 18.9 12.7 5.4 7.9 8.7 5.1 9.9 10.3 5.2 3.8 3.7 3.5 41.4 6.9 1.7 5.2 4.7 9.9 17.4 19.5 6.3 11.6 4.0 31.3 16.0 1.6 24.0 9.9 1.5 3.6 5.3 8.5 3.8 2.6 22.8 2.6 4.0 1.6 19.5 2.7 2.1 9.3 8.4 3.4 0.0 0.1 11.3 11.7 45.8 38.9 34.2 22.2 30.2 10.1 12.0 0.9 38.9 0.0 16.3 40.6 0.0 0.2 0.0 1.1 4.8 0.0 0.3 3.3 0.0 18.6 32.2 0.0 0.0 56.6 1.0 6.2 0.0 11.8 4.2 0.0 0.2 0.1 17.5 41.3 0.0 1.2 4.3 49.8 2.9 0.0 1.6 0.1 0.0 10.6 0.0 1.8 4.3 7.2 60.3 8.1 5.4 9.2 2.6 21.7 9.1 17.2 2.9 0.3 0.1 0.0 0.1 0.0 4.6 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.0 4.1 3.4 3.9 3.8 3.7 5.2 4.7 4.0 3.8 4.0 3.4 4.2 6.4 6.3 12.4 0.8 0.6 6.1 7.8 5.2 0.0 29.6 14.4 6.4 7.2 15.8 1.8 0.0 2.7 0.4 11.4 0.0 7.4 0.2 3.2 17.8 4.6 3.6 6.1 0.1 5.6 16.3 16.7 23.4 4.0 6.3 10.7 8.6 43.6 1.1 0.0 0.4 56.6 12.2 1.9 1.3 1.6 26.4 0.4 1.8 2.8 0.0 5.5 0.0 10.1 0.3 5.1 10.3 17.3 2.8 23.9 1.7 0.8 27.5 0.5 13.1 5.1 6.3 0.8 0.3 4.2 1.0 2.1 0.5 3.6 14.6 10.9 SLC30A4 ZNT4 ENSG00000104154 "Solute carrier family 30 member 4" O14863 15 45479606-45522755 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "prostate: 39.9" "Cell type enhanced" "Detected in many" "Early spermatids: 76.3;Late spermatids: 78.5;Prostatic glandular cells: 39.2;Spermatocytes: 52.1" "Cancer enriched" "Detected in all" 20 "prostate cancer: 34.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (9.49e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-2)" "unprognostic (6.15e-2)" "unprognostic (9.74e-2)" "unprognostic (7.38e-3)" "unprognostic (1.51e-1)" "prognostic favorable (6.02e-4)" "unprognostic (2.66e-2)" "unprognostic (4.72e-3)" "unprognostic (1.29e-2)" "unprognostic (9.83e-2)" "unprognostic (8.28e-3)" "unprognostic (2.01e-3)" 2.8 1.8 2.6 1.9 9.3 0.8 1.9 3.1 4.5 2.8 1.5 3.2 7.0 2.9 2.7 4.2 2.0 2.0 1.9 2.7 2.4 4.2 2.5 1.8 2.7 2.2 2.6 2.5 1.8 4.1 1.5 3.4 2.4 39.9 3.1 3.7 1.3 2.2 1.7 2.5 8.5 3.4 2.1 3.0 2.0 6.3 3.8 1.0 4.7 1.9 3.4 1.8 2.5 7.3 1.8 2.1 0.6 4.7 8.3 5.8 0.4 4.5 4.1 2.7 3.8 0.3 1.5 6.9 1.5 4.7 1.1 1.2 2.0 2.1 2.5 1.7 1.8 0.1 2.0 0.1 5.3 0.1 3.5 4.9 3.4 3.6 0.9 4.2 3.2 3.2 1.0 3.8 5.1 0.8 2.4 0.3 0.1 0.4 0.4 3.6 4.0 1.1 2.2 0.4 1.5 2.3 3.0 3.4 0.8 0.6 2.9 0.2 6.1 4.0 2.3 4.9 1.5 7.0 5.5 1.7 1.7 0.2 3.1 1.3 0.1 0.1 2.2 0.1 2.1 2.0 1.5 1.3 0.2 3.5 1.5 2.1 0.5 1.3 0.1 0.2 0.2 0.7 2.6 9.3 3.1 4.5 2.7 2.4 2.2 2.6 2.4 2.1 3.8 7.3 6.7 3.2 3.9 5.5 6.6 6.8 2.2 1.1 6.8 3.2 2.8 2.2 3.1 0.0 0.1 1.8 16.7 1.0 3.9 15.2 0.0 1.3 76.3 5.0 8.4 6.9 1.2 0.4 14.0 1.1 0.9 7.5 4.6 12.7 1.3 1.9 11.0 3.3 3.1 13.5 9.4 7.1 0.0 1.6 30.8 78.5 6.2 4.4 7.2 9.4 5.3 4.3 10.3 6.0 28.8 0.7 22.0 8.2 6.0 39.2 32.4 12.5 0.7 2.2 6.6 6.2 5.2 52.1 19.9 7.4 6.5 0.3 5.4 3.6 5.1 1.7 SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.0" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA013810: AB_1857095" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (5.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (1.22e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.51e-2)" 11.5 23.9 5.7 11.1 5.8 11.7 12.7 6.6 6.5 20.7 26.3 16.3 45.1 7.2 13.7 12.0 6.5 9.6 7.4 6.9 6.6 28.7 107.6 17.7 6.3 7.2 6.9 4.9 19.1 15.2 5.8 13.5 11.7 21.3 17.0 7.1 66.5 12.8 3.5 18.5 37.4 10.0 6.8 7.6 19.4 6.4 7.0 5.5 10.9 5.8 12.4 14.3 6.5 6.5 22.1 23.4 18.7 41.4 42.0 29.8 68.8 38.3 58.0 26.0 30.1 33.5 18.8 17.2 15.2 33.0 32.9 53.3 35.8 21.8 29.0 15.2 19.9 14.2 18.7 37.6 102.3 26.1 20.6 36.1 48.3 33.6 54.6 17.4 24.0 19.6 32.8 30.9 24.8 23.6 17.9 13.2 30.4 84.2 26.0 18.3 49.1 17.2 23.6 27.2 17.7 23.1 37.0 73.0 101.5 26.2 37.2 22.0 22.3 19.3 11.9 39.1 23.2 18.5 40.5 23.6 31.9 24.2 23.1 3.0 20.9 2.5 2.3 26.8 3.2 1.7 1.6 2.4 16.3 1.5 1.8 1.7 8.2 4.4 31.0 2.3 1.8 7.6 5.7 5.8 6.6 6.5 6.9 6.6 7.2 6.9 11.7 6.8 7.0 6.5 8.0 35.3 33.5 7.5 6.6 15.2 10.6 27.4 10.2 12.6 21.4 14.9 7.4 21.5 50.8 5.5 33.3 16.5 6.9 40.2 9.8 18.3 0.3 16.2 15.6 11.6 9.0 25.4 16.8 27.2 24.1 16.0 15.3 14.5 5.1 11.4 11.4 97.1 43.4 6.7 17.0 18.9 42.7 39.4 19.9 0.9 6.2 40.3 12.4 20.6 21.8 12.2 4.1 16.1 12.3 22.3 11.1 7.2 16.1 28.9 61.7 24.7 30.1 11.2 6.6 8.4 15.2 24.4 30.7 15.1 15.8 22.4 5.5 15.2 19.9 22.6 SLC35E1 FLJ14251 ENSG00000127526 "Solute carrier family 35 member E1" Q96K37 19 16549831-16572415 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016570, HPA062214" Approved Enhanced "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA016570: AB_2190214, HPA062214: AB_2684713" "unprognostic (1.76e-2)" "unprognostic (2.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.92e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.35e-2)" "unprognostic (1.04e-1)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (9.07e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (2.54e-1)" "unprognostic (3.75e-2)" 10.7 9.8 5.9 5.6 4.8 8.0 9.6 3.7 6.6 9.6 6.3 9.2 6.6 8.5 5.9 11.5 7.4 6.1 10.1 5.6 4.7 7.8 11.4 9.1 7.1 4.8 5.9 8.8 22.3 15.2 11.2 7.2 5.0 11.7 6.1 7.4 15.4 10.0 20.5 11.9 7.7 6.8 3.6 6.7 15.3 4.1 9.1 8.5 9.2 14.0 8.1 10.1 8.7 4.5 26.2 10.4 6.9 16.2 25.2 19.8 16.4 17.8 20.3 15.1 18.2 11.8 18.7 13.6 30.2 29.3 14.9 17.6 19.7 21.5 15.2 15.8 29.5 11.9 11.6 14.4 21.1 19.6 14.5 16.5 24.2 17.0 24.5 19.2 14.8 16.0 19.9 17.3 19.4 25.3 15.3 9.3 8.1 24.8 34.6 14.9 10.6 16.6 15.7 16.1 11.9 11.9 12.3 19.6 11.5 8.3 14.7 9.9 15.3 19.5 9.6 26.9 21.2 23.6 26.9 15.1 29.3 21.4 12.6 1.8 1.3 3.2 1.3 0.9 1.8 2.2 1.4 1.3 1.0 0.8 1.0 0.8 1.3 1.8 2.0 1.1 1.8 1.1 5.9 4.8 3.7 6.6 5.6 4.7 4.8 5.9 5.0 3.6 9.1 4.5 21.7 38.5 42.5 6.8 14.9 21.9 15.3 22.1 5.7 28.8 34.1 21.5 16.1 22.8 31.3 29.5 35.5 14.4 43.3 25.2 0.0 20.4 3.6 26.6 20.1 20.2 18.5 13.7 13.9 36.8 29.8 14.8 13.3 50.8 8.2 21.2 22.9 26.9 17.4 30.3 13.9 29.7 8.2 21.1 28.0 4.2 17.1 23.3 8.8 10.3 22.8 19.4 17.5 9.0 6.2 41.7 13.1 21.1 29.3 30.9 22.1 7.0 24.0 29.4 6.6 30.1 14.3 10.2 14.3 13.6 25.9 32.6 29.4 16.2 20.4 28.4 SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 443.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 386.1" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" 8.2 5.3 20.0 38.5 18.6 26.0 81.8 48.2 18.9 13.6 0.6 39.3 16.7 16.4 8.7 26.6 15.5 16.6 44.6 15.3 42.3 20.3 6.4 13.2 64.4 44.1 25.4 9.9 23.8 78.7 19.3 22.5 34.6 29.5 38.5 79.0 20.5 35.6 90.7 30.5 22.9 27.8 48.4 31.9 21.3 1.1 26.8 59.5 42.5 82.4 54.4 23.4 11.2 59.7 77.6 79.2 28.2 104.9 12.4 4.5 142.8 60.6 98.2 27.3 42.7 136.6 74.9 176.3 113.0 74.7 83.6 116.5 94.8 124.5 50.4 109.6 49.8 12.3 127.4 51.2 108.3 126.1 4.5 21.7 186.7 8.2 325.1 67.5 61.6 112.0 65.2 144.2 86.5 96.5 112.7 22.0 104.1 0.1 122.7 99.8 6.9 124.6 105.4 109.8 111.6 77.2 126.2 152.9 71.7 108.0 88.9 91.1 129.8 21.2 19.7 0.6 62.7 136.2 126.5 386.1 67.9 242.2 18.6 1.0 0.8 26.3 51.8 0.2 71.0 50.4 54.1 61.0 34.9 57.8 62.6 57.1 2.4 68.3 0.4 44.3 63.5 46.4 20.0 18.6 48.2 18.9 15.3 42.3 44.1 25.4 34.6 48.4 26.8 59.7 10.3 35.3 44.7 75.4 150.0 97.8 73.8 103.8 30.1 443.5 136.5 64.8 207.5 38.6 61.8 213.3 141.8 106.9 216.3 99.3 3.9 56.3 0.2 78.1 9.8 26.7 40.6 25.6 104.7 46.4 79.3 14.6 19.4 123.7 3.8 30.9 5.7 6.1 12.2 8.4 157.8 73.6 79.3 12.9 76.1 0.3 2.1 23.3 26.6 30.9 13.6 51.4 107.1 94.5 59.7 53.5 52.8 0.7 138.8 66.5 23.6 1.1 29.7 54.2 0.0 62.9 34.5 0.1 0.4 70.3 122.7 185.7 167.9 1.6 93.6 75.4 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.2;testis: 40.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Cytotrophoblasts: 32.8;Distal enterocytes: 18.8;Glandular and luminal cells: 21.3;Paneth cells: 21.7;Proximal enterocytes: 35.5;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 42.1;OE19: 31.8;RT4: 12.3;SK-BR-3: 15.4;T-47d: 20.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049391: AB_2680743, HPA059078: AB_2732630" "unprognostic (4.53e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (9.03e-3)" "unprognostic (2.12e-3)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (4.36e-2)" "unprognostic (4.39e-3)" "unprognostic (4.82e-2)" "unprognostic (2.04e-3)" "prognostic favorable (5.51e-6)" "unprognostic (3.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" 2.1 0.2 11.0 1.5 8.9 0.4 2.6 9.5 11.4 2.3 5.5 11.5 14.4 2.0 2.0 4.9 1.8 2.6 5.7 9.0 11.1 9.4 0.1 1.2 0.4 12.9 9.8 0.9 1.6 0.2 0.3 4.3 12.3 8.0 7.1 0.6 6.1 4.0 0.6 1.8 19.2 1.7 9.8 0.2 5.6 40.1 12.5 0.1 0.5 0.9 0.8 4.9 2.5 9.7 6.6 2.2 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 4.6 42.1 0.0 7.0 0.0 0.6 6.9 0.0 6.0 0.0 0.0 0.0 0.8 0.7 0.3 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.6 31.8 4.5 0.0 0.0 1.1 0.0 12.3 0.1 0.2 7.2 15.4 0.1 0.8 20.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 2.1 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.8 0.5 0.1 0.3 0.1 0.2 11.0 8.9 9.5 11.4 9.0 11.1 12.9 9.8 12.3 9.8 12.5 9.7 3.8 9.6 3.1 0.0 0.1 0.6 2.2 5.3 1.8 0.4 3.2 2.4 0.7 4.3 5.3 23.9 2.1 32.8 0.0 18.8 1.9 6.6 1.1 8.9 1.1 10.8 0.0 0.0 0.1 2.0 0.9 0.4 4.6 21.3 0.0 5.9 0.0 0.0 2.6 0.0 0.0 6.0 6.1 0.0 1.3 3.2 0.9 0.2 1.8 2.8 0.0 0.0 0.0 0.0 0.0 5.2 21.7 0.4 0.1 4.3 35.5 0.1 2.4 0.1 0.0 0.4 0.6 0.6 0.8 2.3 1.1 52.1 0.2 1.3 10.8 5.8 SLC5A8 AIT ENSG00000256870 "Solute carrier family 5 member 8" Q8N695 12 101155493-101210238 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Symport, Transport" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 20.3;kidney: 5.6;thyroid gland: 15.5" "Cell type enhanced" "Detected in some" "Club cells: 9.1;Early spermatids: 7.9;Enteroendocrine cells: 31.5;Excitatory neurons: 14.6;Horizontal cells: 10.1;Inhibitory neurons: 17.3;Proximal tubular cells: 21.4" "Group enriched" "Detected in many" 4 "breast cancer: 2.7;renal cancer: 7.6;thyroid cancer: 5.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "SK-BR-3: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "prognostic favorable (9.04e-6)" "unprognostic (1.84e-1)" "unprognostic (1.17e-2)" "unprognostic (1.27e-3)" "unprognostic (1.24e-1)" "unprognostic (5.20e-1)" "unprognostic (1.16e-2)" "prognostic favorable (1.97e-4)" "unprognostic (6.16e-2)" "unprognostic (2.30e-2)" "unprognostic (2.87e-2)" 0.0 2.4 0.5 0.0 0.5 0.0 0.0 0.3 1.2 20.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 5.6 0.0 0.9 0.0 0.9 0.3 1.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.1 0.9 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.2 1.5 0.2 15.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.4 0.8 0.9 0.3 0.5 0.5 1.5 0.8 0.0 0.0 5.3 1.3 0.0 0.0 0.0 4.6 0.0 3.9 0.1 0.1 0.6 0.0 9.1 1.8 0.0 0.0 0.0 0.3 1.9 0.0 7.9 0.0 0.1 0.0 31.5 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 17.3 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.6 0.2 21.4 2.1 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.9 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 331.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 74.1;Kupffer cells: 90.0;Proximal tubular cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 9.3;eosinophil: 14.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 14.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.8;BEWO: 110.6;K-562: 136.9;NTERA-2: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" 27.6 15.2 1.2 7.0 7.1 1.6 27.7 5.5 7.6 31.3 42.8 12.5 36.3 43.6 4.8 37.5 45.9 18.6 7.9 3.4 6.5 119.3 6.9 15.4 4.5 3.4 3.1 67.5 19.9 331.1 15.8 16.0 5.8 39.2 13.7 13.9 23.8 35.5 49.4 31.6 24.2 20.9 0.0 18.5 63.4 21.2 6.7 4.9 23.7 15.4 9.0 29.9 37.5 1.4 1.6 0.0 52.9 0.1 68.8 8.5 110.6 6.0 26.3 0.3 2.0 60.4 3.6 0.4 0.8 13.9 5.4 11.7 8.5 3.5 0.3 0.0 5.2 0.6 0.3 0.0 25.5 0.2 35.8 54.1 33.2 0.9 0.9 11.6 5.2 5.4 136.9 0.3 1.5 1.2 0.3 0.8 64.0 12.9 47.4 0.1 0.9 12.5 0.7 21.4 8.2 0.3 0.2 12.0 32.3 60.1 42.8 0.6 0.5 2.3 1.8 0.7 0.0 0.3 15.9 0.2 6.9 0.0 0.4 9.3 0.1 14.0 0.0 0.1 1.1 0.1 0.9 0.1 0.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.5 2.3 1.2 7.1 5.5 7.6 3.4 6.5 3.4 3.1 5.8 0.0 6.7 1.4 0.5 16.0 15.0 2.3 1.8 3.1 28.8 6.4 29.0 26.4 31.6 15.2 5.7 0.0 9.0 16.5 0.0 18.7 0.5 8.3 5.9 1.9 2.2 13.6 74.1 2.1 33.0 0.0 24.8 2.4 4.4 15.5 53.5 18.4 5.1 27.3 66.4 1.3 59.2 26.9 53.5 33.7 4.1 90.0 3.3 3.1 9.6 15.3 19.6 15.9 0.5 39.3 0.0 4.0 2.6 3.0 6.5 7.9 1.6 26.4 27.3 144.8 1.0 4.4 0.0 2.8 4.7 1.1 1.3 25.3 3.0 41.3 2.9 3.4 18.5 32.3 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;stomach 1: 26.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 41.3;Early spermatids: 46.5;Gastric mucus-secreting cells: 41.8;Intestinal goblet cells: 23.4;Late spermatids: 31.4;Paneth cells: 38.7;Undifferentiated cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.0;OE19: 37.3;RT4: 16.9;SK-BR-3: 14.7;T-47d: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" 0.0 0.1 1.4 2.1 0.7 0.0 1.4 0.8 1.5 1.4 0.2 20.0 6.3 0.1 3.9 0.3 0.3 1.1 0.0 1.9 0.9 5.4 0.0 0.1 0.1 1.4 0.7 0.0 0.0 5.8 1.0 0.0 1.5 5.8 20.7 0.1 4.9 2.1 6.4 0.8 3.4 0.7 0.8 0.0 26.4 5.7 1.2 0.4 1.0 6.2 4.5 1.0 0.0 0.5 10.0 6.1 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.2 0.0 3.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 3.4 2.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 7.7 0.0 0.1 0.2 37.3 5.0 0.0 0.1 0.0 1.1 16.9 0.1 0.0 0.0 14.7 0.0 0.0 18.5 0.0 0.0 0.0 0.7 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.8 1.5 1.9 0.9 1.4 0.7 1.5 0.8 1.2 0.5 0.0 0.0 0.0 2.0 0.3 0.4 0.2 0.1 0.0 0.0 1.1 0.1 0.8 0.0 0.3 9.2 0.0 0.5 0.0 41.3 0.0 0.2 46.5 0.5 0.2 0.3 9.7 0.0 3.0 0.0 0.0 0.0 41.8 3.1 0.0 0.0 0.0 0.0 0.1 0.0 14.6 23.4 6.1 0.0 0.4 31.4 0.6 0.0 0.0 5.6 0.0 0.5 0.0 1.0 1.0 8.5 38.7 0.0 0.2 4.1 3.2 1.4 0.1 0.1 0.0 0.5 0.1 4.5 0.2 0.0 0.6 0.3 0.2 0.0 29.6 0.8 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SLFN12L ENSG00000205045 "Schlafen family member 12 like" Q6IEE8 17 35464249-35487857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 8 "dendritic cells: 16.0;NK-cells: 42.2;T-cells: 31.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;NK-cells: 3.6;T-cells: 1.9" "Cell line enhanced" "Detected in some" "HDLM-2: 9.7;Karpas-707: 5.5" HPA024447 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" 0.6 0.3 0.9 2.4 0.9 3.0 0.6 2.5 1.8 0.5 0.9 0.6 1.7 0.5 0.3 0.3 0.3 1.0 0.2 0.7 0.4 0.3 0.6 1.3 3.0 0.3 0.0 0.4 0.3 0.1 0.0 0.2 0.3 0.3 0.8 0.8 0.9 0.2 0.5 0.6 1.5 0.4 0.0 3.1 1.2 0.3 0.5 1.0 0.4 0.3 2.2 0.7 0.1 1.5 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.6 1.4 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.7 9.7 0.1 1.3 0.8 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.3 5.5 0.1 0.0 0.4 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.3 0.2 0.2 0.1 0.4 0.1 0.1 0.1 0.0 2.0 0.6 0.3 1.2 0.5 0.2 2.0 2.0 0.1 0.2 0.3 0.5 1.0 0.3 1.0 1.9 0.0 0.8 0.3 0.8 1.4 0.2 0.3 1.0 1.0 0.9 3.6 0.1 0.2 0.5 0.4 0.9 0.9 2.5 1.8 0.7 0.4 0.3 0.0 0.3 0.0 0.5 1.5 3.5 3.2 2.7 0.0 1.5 0.3 0.6 0.4 0.0 0.0 0.3 0.3 1.3 1.5 0.7 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.8 0.5 0.2 1.4 0.0 0.4 0.0 0.0 0.0 0.5 1.5 0.3 1.3 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.4 0.1 0.0 1.1 0.0 1.0 0.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.7 0.4 0.0 0.3 0.1 0.0 31.7 0.1 0.1 0.2 SLFN14 ENSG00000236320 "Schlafen family member 14" P0C7P3 17 35543985-35560819 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "bone marrow: 3.9" "Group enriched" "Detected in some" 41 "Erythroid cells: 16.8;Macrophages: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HEL: 18.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022994, HPA023065" Uncertain NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA022994: AB_10670035, HPA023065: AB_2671055" "unprognostic (4.27e-3)" "unprognostic (4.72e-4)" "unprognostic (1.21e-1)" "unprognostic (6.43e-2)" "unprognostic (1.07e-3)" "unprognostic (6.50e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-1)" "unprognostic (5.33e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-1)" "unprognostic (7.59e-8)" "unprognostic (1.21e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-3)" 0.0 0.0 0.1 0.3 0.1 3.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 18.7 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.8 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SLMAP "KIAA1601, SLAP" ENSG00000163681 "Sarcolemma associated protein" Q14BN4 3 57755450-57930003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 295.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002357, HPA002358" Enhanced Approved "Endoplasmic reticulum" NA NA 9200 "Cluster 49: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "HPA002357: AB_1080023, HPA002358: AB_1080021" "unprognostic (3.70e-1)" "unprognostic (2.87e-2)" "unprognostic (1.82e-3)" "unprognostic (3.43e-2)" "unprognostic (3.34e-1)" "unprognostic (6.18e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.58e-6)" "unprognostic (8.18e-2)" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (6.08e-2)" 25.9 28.1 8.3 35.2 14.7 15.5 21.9 13.4 9.2 25.6 11.3 126.5 34.0 93.5 14.2 116.8 48.6 31.6 134.7 7.5 7.3 24.9 16.4 17.6 16.4 7.8 7.4 37.5 16.1 36.6 11.5 23.5 8.3 65.6 38.2 20.4 20.1 100.3 64.0 21.5 37.7 137.6 6.5 14.9 52.3 31.8 9.2 19.8 28.7 42.0 18.3 87.5 29.0 8.7 43.3 23.1 23.0 25.7 31.8 28.9 24.2 40.8 41.9 27.0 25.5 59.4 54.6 25.1 17.9 30.4 48.4 23.5 38.5 54.5 36.8 32.2 20.6 49.9 31.1 47.6 29.1 47.8 26.5 20.0 39.1 33.6 60.8 38.1 31.8 25.0 39.7 23.7 28.5 11.7 28.0 20.4 29.7 29.3 38.7 12.4 21.0 28.0 47.7 44.3 10.0 12.8 49.9 37.4 23.7 26.7 19.9 27.4 38.1 33.0 23.1 28.2 52.8 28.9 57.1 36.7 25.5 45.4 27.9 3.3 3.8 10.9 3.6 2.7 3.2 3.7 2.8 3.2 3.2 2.5 3.2 3.4 9.5 5.2 2.4 1.4 4.1 3.6 8.3 14.7 13.4 9.2 7.5 7.3 7.8 7.4 8.3 6.5 9.2 8.7 17.3 38.5 39.6 90.1 25.6 92.0 45.4 49.3 54.1 28.0 25.0 23.7 295.9 40.0 40.0 33.1 50.1 19.0 34.4 53.9 19.6 45.8 40.2 45.9 24.6 22.8 14.4 28.6 113.3 34.3 12.2 28.6 41.3 72.4 3.8 34.8 18.2 22.7 15.6 32.0 121.5 26.8 20.3 20.3 25.9 26.2 32.6 27.8 28.4 76.8 25.1 86.8 34.0 101.0 97.7 64.1 36.6 71.8 39.0 93.3 36.4 24.8 46.5 32.4 52.6 26.8 82.2 87.4 47.0 54.5 73.3 16.3 26.1 52.0 28.7 126.9 SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.9;Endothelial cells: 76.3;Late spermatids: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.2;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 5 "granulocytes: 46.2;monocytes: 22.2" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB005389: AB_656608" "unprognostic (8.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-1)" "unprognostic (6.85e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (2.30e-1)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-3)" "unprognostic (3.15e-2)" 19.6 5.3 16.7 10.9 21.9 5.8 15.9 15.3 18.2 20.4 6.9 20.4 15.4 29.0 32.7 16.3 24.4 17.1 13.1 13.2 16.6 12.6 20.2 12.3 17.6 14.6 18.3 11.7 13.3 29.1 6.0 11.4 14.5 12.5 20.8 6.5 12.9 17.2 20.7 24.4 15.7 30.4 13.6 14.0 10.6 13.9 16.4 18.3 17.4 17.8 13.7 17.9 8.9 13.6 9.6 12.6 23.5 27.3 8.7 12.8 11.5 13.9 32.6 22.0 16.4 6.2 34.0 9.8 8.0 31.8 9.7 14.1 26.6 30.2 12.8 0.0 13.5 0.0 10.0 13.1 23.2 15.8 2.4 17.6 35.2 11.8 22.9 17.9 110.7 20.7 11.1 0.4 27.0 9.6 24.4 0.3 21.8 15.3 14.6 47.0 21.1 28.5 25.9 17.1 35.3 17.6 18.8 40.3 9.6 14.1 14.0 0.2 32.4 10.5 14.5 11.3 8.6 31.1 0.0 56.1 16.7 0.3 11.1 46.2 3.6 1.5 0.0 9.4 0.0 0.0 0.6 0.0 6.8 0.1 0.3 0.0 0.0 2.4 22.2 0.0 1.3 1.3 16.7 21.9 15.3 18.2 13.2 16.6 14.6 18.3 14.5 13.6 16.4 13.6 62.9 9.6 10.9 54.9 0.1 11.5 17.5 22.0 45.5 6.6 8.6 9.3 3.6 12.8 16.3 14.7 14.6 5.2 0.8 13.2 7.9 12.6 195.9 19.5 12.1 76.3 9.1 8.4 47.7 18.5 2.7 11.5 12.2 24.8 0.0 10.0 10.4 12.0 2.5 10.1 43.2 10.4 28.5 6.5 2.7 80.7 4.4 4.5 1.8 26.2 3.2 5.3 0.0 66.9 22.0 12.0 10.2 5.7 0.3 17.5 6.6 11.5 12.7 5.9 0.0 19.0 10.6 8.3 16.8 19.9 12.6 2.2 1.2 6.9 8.8 17.2 SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 338.4;dendritic cells: 258.0;Kupffer cells: 284.4;Macrophages: 256.8;monocytes: 291.7;Plasma cells: 224.4;T-cells: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 177.1;THP-1: 302.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" 65.3 24.0 44.2 136.7 50.7 80.9 33.3 35.7 54.3 43.9 33.8 33.5 17.5 17.9 14.1 26.2 30.7 46.3 17.2 52.1 48.2 19.2 73.5 58.4 205.8 41.8 41.1 17.1 23.8 27.4 43.9 38.0 42.9 20.0 32.1 48.5 29.5 19.0 30.0 33.3 99.2 40.1 38.3 216.3 41.8 17.0 48.0 158.3 19.2 21.2 199.5 52.2 19.3 47.2 25.1 9.3 22.0 22.2 31.4 60.0 12.2 38.4 34.7 38.9 37.9 11.7 16.8 93.1 18.4 34.4 16.0 10.2 41.1 29.4 53.3 177.1 34.8 51.7 14.2 25.5 28.1 54.3 153.7 51.7 24.3 50.4 21.6 19.1 22.4 71.6 94.9 95.2 47.0 16.8 79.3 51.2 13.4 24.7 84.7 30.3 20.4 96.3 18.9 28.9 37.1 17.1 18.1 46.1 29.9 16.8 14.8 302.3 12.4 42.8 17.6 40.2 29.9 31.3 37.1 75.9 38.8 53.1 28.2 12.4 87.7 102.0 14.5 153.8 18.2 43.7 23.3 22.1 49.3 58.6 32.4 30.1 195.4 31.6 195.8 9.3 35.5 52.1 44.2 50.7 35.7 54.3 52.1 48.2 41.8 41.1 42.9 38.3 48.0 47.2 12.8 25.6 28.4 10.1 338.4 18.0 11.4 8.5 4.0 34.7 17.5 13.6 15.3 30.0 24.5 7.3 22.9 5.5 258.0 11.0 5.9 12.6 12.7 78.2 15.8 18.7 9.5 66.7 75.7 18.7 9.6 17.1 26.0 25.0 28.4 10.4 38.6 66.3 43.5 26.9 52.4 9.8 12.2 284.4 140.1 19.5 5.3 256.8 28.4 89.9 291.7 15.0 129.8 54.8 33.6 17.1 8.9 4.9 224.4 9.6 10.0 9.1 70.2 25.6 32.9 12.8 27.9 15.9 11.6 12.7 17.8 4.1 199.9 14.6 9.5 14.6 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1580.8;intestine: 753.9;kidney: 844.8" "Group enriched" "Detected in many" 12 "Proximal enterocytes: 4096.4;Proximal tubular cells: 1884.8" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.7;pancreatic cancer: 37.4;renal cancer: 78.4;stomach cancer: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 154.9;HEL: 74.0;Hep G2: 117.7;MOLT-4: 113.8;OE19: 185.0;REH: 61.5;U-937: 87.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA045046: AB_10964444, HPA056027: AB_2683012" "unprognostic (2.18e-4)" "unprognostic (4.63e-1)" "unprognostic (5.68e-2)" "unprognostic (9.60e-2)" "unprognostic (1.93e-1)" "unprognostic (6.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.13e-10)" "unprognostic (1.68e-2)" "unprognostic (2.14e-1)" "unprognostic (8.36e-2)" "unprognostic (3.11e-2)" 0.2 0.0 4.2 2.7 5.0 91.3 0.8 4.1 6.8 0.6 5.5 30.4 753.9 0.7 1580.8 0.4 2.8 82.0 0.1 4.7 4.3 844.8 35.8 0.4 1.6 4.3 4.6 0.3 8.0 0.2 3.5 0.1 4.3 1.0 24.5 91.6 0.3 2.3 0.3 1.2 628.2 0.8 4.0 1.2 150.1 2.9 4.6 50.4 0.2 0.1 2.0 0.2 0.2 4.4 0.0 0.0 0.2 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 154.9 0.5 0.2 7.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 74.0 1.0 117.7 0.0 6.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 10.7 1.5 0.1 0.1 0.0 113.8 15.8 0.0 185.0 0.3 61.5 0.1 4.3 1.6 0.1 1.4 2.3 0.1 0.1 1.6 0.4 0.0 1.9 0.0 0.0 0.4 1.2 0.1 0.0 0.0 6.5 0.0 87.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.3 0.4 1.0 0.0 5.9 0.0 1.5 1.6 0.8 4.2 5.0 4.1 6.8 4.7 4.3 4.3 4.6 4.3 4.0 4.6 4.4 0.1 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 14.1 0.1 0.8 0.2 188.8 0.0 58.8 27.1 0.0 0.5 35.1 238.7 4.0 5.1 7.7 0.8 0.3 139.0 22.3 0.7 12.4 0.2 0.3 205.4 13.0 1.3 0.2 0.4 36.3 0.1 0.0 0.1 136.6 0.0 0.6 0.0 15.0 0.3 11.6 0.0 0.0 0.7 4.1 0.0 0.0 0.2 12.4 178.9 0.0 1.7 0.3 4096.4 1884.8 0.0 34.9 0.0 0.2 0.3 0.6 0.7 0.0 0.0 0.0 7.4 0.0 141.3 0.2 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940709-21994837 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 644.3;Distal tubular cells: 608.4;Syncytiotrophoblasts: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" No No 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" Cytosol "HPA029849: AB_10602072, HPA029852: AB_10611521" "unprognostic (2.51e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (7.49e-4)" "prognostic unfavorable (7.79e-8)" "unprognostic (1.02e-2)" "unprognostic (2.72e-1)" "unprognostic (3.18e-3)" "unprognostic (3.95e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.85e-5)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (8.50e-2)" 29.7 94.3 52.0 34.7 53.5 50.8 49.6 56.0 61.9 42.7 43.7 52.0 54.9 44.7 63.6 30.6 28.6 40.5 53.0 53.9 50.2 119.9 44.3 36.2 47.8 48.6 46.7 91.2 24.1 28.0 31.5 114.2 49.1 136.0 50.4 49.5 39.7 42.2 34.6 21.4 50.9 39.6 47.0 41.3 39.3 30.2 53.9 50.7 55.3 32.5 47.3 55.1 32.0 49.6 664.3 161.2 265.3 107.1 71.9 121.4 86.3 174.6 102.6 261.7 249.1 204.0 213.0 239.5 59.8 180.0 722.9 142.2 265.5 318.2 508.2 111.0 128.6 124.4 201.0 145.5 129.4 242.2 103.8 76.8 93.7 266.4 497.2 189.2 254.5 93.6 270.6 32.7 366.7 139.2 181.3 244.1 474.9 149.0 244.3 176.0 188.5 182.9 354.3 90.1 131.4 105.7 143.1 181.8 489.1 687.6 163.9 101.3 232.3 194.4 193.6 405.0 294.5 23.8 52.6 142.2 378.4 107.5 275.6 9.1 57.5 102.5 18.9 59.9 23.7 34.6 29.6 33.3 51.1 22.0 19.1 22.8 55.7 31.4 73.9 10.7 55.4 37.3 52.0 53.5 56.0 61.9 53.9 50.2 48.6 46.7 49.1 47.0 53.9 49.6 43.4 25.6 21.9 33.6 61.5 65.9 203.0 206.1 42.1 35.7 116.2 66.3 36.1 81.5 115.0 110.3 12.5 644.3 46.7 61.2 608.4 246.3 1.9 126.4 70.4 61.9 58.8 95.2 45.6 152.3 313.1 86.6 57.6 215.9 40.5 249.5 59.6 49.8 364.7 21.9 40.2 103.6 146.5 157.3 200.3 7.1 95.4 153.1 92.5 21.5 250.7 46.8 48.4 22.1 8.1 165.6 63.9 103.4 45.6 276.2 137.0 466.7 78.9 43.2 65.7 76.6 114.2 6.0 181.3 54.1 50.6 869.6 63.7 271.2 119.1 153.1 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SMTNL2 FLJ42461 ENSG00000188176 "Smoothelin like 2" Q2TAL5 17 4583999-4608319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 500.8;tongue: 136.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.7;Collecting duct cells: 9.2;Distal tubular cells: 33.2;Proximal tubular cells: 35.4;Sertoli cells: 26.3;Skeletal myocytes: 8.2" "Cancer enhanced" "Detected in many" "renal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "CACO-2: 49.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025706 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Nuclear speckles" "HPA025706: AB_1848935" "unprognostic (8.62e-2)" "unprognostic (5.40e-2)" "unprognostic (7.13e-2)" "unprognostic (2.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.87e-2)" "unprognostic (4.89e-3)" "unprognostic (2.73e-1)" "unprognostic (3.73e-3)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (5.89e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-3)" "unprognostic (2.22e-1)" 8.3 0.1 0.9 1.5 1.1 0.0 2.5 0.8 1.6 3.4 1.0 1.2 0.2 3.9 2.3 8.0 7.2 2.1 18.2 2.5 0.7 31.8 0.2 4.7 0.2 0.9 1.0 6.7 0.6 1.1 2.3 4.9 1.0 5.0 0.5 0.1 6.1 0.9 500.8 1.5 1.2 2.5 0.7 0.8 1.0 1.3 1.0 0.2 1.4 136.2 0.1 4.5 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.4 0.0 0.8 0.0 2.7 0.0 0.6 0.0 2.9 0.0 0.0 5.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.2 0.0 0.0 0.0 0.1 5.4 0.0 11.4 0.0 0.0 0.0 0.0 10.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.8 1.6 2.5 0.7 0.9 1.0 1.0 0.7 1.0 0.8 0.3 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 8.7 0.0 0.6 9.2 0.0 0.8 0.0 0.0 33.2 0.1 0.1 1.8 1.3 1.3 0.0 0.0 0.1 0.0 1.5 6.1 0.0 2.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.3 1.8 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 35.4 0.0 0.0 26.3 8.2 7.6 0.0 0.5 0.1 0.0 0.5 0.3 0.1 0.2 0.3 SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 31.3" "Cell type enhanced" "Detected in some" "dendritic cells: 19.7;granulocytes: 9.5;Kupffer cells: 14.6;Langerhans cells: 9.3;Macrophages: 9.4;NK-cells: 17.5;Plasma cells: 14.0;T-cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NB-4: 18.2;RPMI-8226: 28.6" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA071127: AB_2686346" "unprognostic (1.03e-2)" "prognostic favorable (1.39e-4)" "unprognostic (2.20e-2)" "unprognostic (6.19e-4)" "unprognostic (3.05e-1)" "unprognostic (2.85e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (3.24e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.58e-4)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" 0.7 0.5 1.5 2.4 2.4 1.8 0.4 0.0 3.3 0.6 0.0 1.2 1.5 0.6 0.3 0.6 0.8 1.0 2.4 1.9 0.0 0.7 0.8 2.2 3.9 2.1 0.0 0.5 1.7 1.5 0.7 0.1 3.7 0.8 0.3 0.3 1.2 0.2 31.3 0.6 3.7 0.2 0.0 6.9 3.3 0.9 0.0 0.8 0.9 7.3 2.6 1.4 0.5 0.0 0.3 0.9 0.3 1.3 0.0 0.0 0.6 0.3 0.0 0.0 0.1 3.5 0.3 2.3 0.5 0.0 0.8 0.8 0.3 0.2 0.0 0.4 1.2 1.1 0.1 1.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.5 2.1 4.3 0.0 3.2 0.2 18.2 0.4 0.3 0.4 3.9 0.3 28.6 0.0 0.4 1.7 0.2 0.7 0.0 0.2 0.4 1.2 2.2 0.3 0.1 1.0 0.2 0.0 0.7 4.2 4.0 0.3 4.9 0.5 5.2 14.1 48.5 10.2 5.3 18.8 7.8 16.7 9.8 16.7 6.1 10.0 6.4 30.9 1.1 1.5 11.9 21.4 10.9 1.5 2.4 0.0 3.3 1.9 0.0 2.1 0.0 3.7 0.0 0.0 0.0 0.3 3.2 0.0 2.0 8.5 0.5 0.1 0.4 0.0 0.2 0.4 0.5 2.0 0.0 0.7 0.0 0.0 0.0 19.7 0.0 1.9 0.1 0.0 0.6 0.0 0.4 0.0 0.4 6.4 0.4 0.5 0.2 0.5 0.1 9.5 0.0 0.4 0.1 6.9 0.0 3.7 0.1 2.0 14.6 9.3 0.3 0.0 9.4 5.4 0.0 5.3 0.1 17.5 1.0 1.9 0.1 1.1 0.4 14.0 0.1 0.0 0.2 1.0 0.9 0.0 0.7 0.4 0.0 1.5 0.2 0.3 0.1 14.0 0.0 0.3 0.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNRPN "HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN" ENSG00000128739 "Small nuclear ribonucleoprotein polypeptide N" P63162 15 24823637-24978723 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 457.8;Horizontal cells: 333.1;Proximal tubular cells: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 789.5;SuSa: 505.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003482, HPA067842" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA003482: AB_1857337, HPA067842: AB_2685909" "unprognostic (9.91e-2)" "unprognostic (1.03e-3)" "unprognostic (2.79e-1)" "unprognostic (1.66e-2)" "unprognostic (3.71e-2)" "unprognostic (2.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.72e-2)" "unprognostic (9.44e-3)" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (6.59e-2)" "prognostic favorable (8.93e-8)" "unprognostic (4.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (6.74e-2)" 54.8 181.8 453.6 46.5 472.5 36.5 69.4 441.8 553.5 112.3 351.6 87.3 36.4 65.2 332.5 44.0 121.9 141.2 483.2 474.3 510.7 192.0 69.9 76.4 93.5 454.7 440.5 147.8 111.8 243.4 375.5 37.4 458.5 174.2 34.8 161.7 125.7 147.6 232.7 38.2 62.5 59.0 415.8 85.2 88.3 60.7 467.8 136.8 300.4 272.4 80.6 82.5 66.4 470.8 1.0 148.6 260.8 180.1 153.4 69.5 1.1 46.9 100.0 31.7 57.8 138.1 69.1 0.2 91.6 118.7 47.9 26.7 0.0 142.7 18.2 81.1 0.1 89.3 90.1 151.5 181.8 107.1 76.8 132.6 60.6 69.4 81.8 213.2 95.7 189.8 24.8 0.4 183.3 0.0 216.9 1.5 789.5 0.0 63.0 113.3 97.8 0.5 172.3 222.2 155.7 147.1 0.7 3.6 174.0 505.7 93.6 271.3 62.3 79.2 78.2 0.3 28.8 215.3 126.9 140.4 65.9 72.9 59.8 234.8 68.0 106.8 313.9 74.2 355.8 371.9 385.3 359.0 65.2 342.1 508.0 420.8 18.5 291.2 77.4 531.9 434.4 581.7 453.6 472.5 441.8 553.5 474.3 510.7 454.7 440.5 458.5 415.8 467.8 470.8 57.1 9.6 45.5 0.0 106.2 2.2 102.6 4.4 53.5 171.0 77.1 96.5 185.2 218.8 23.0 178.4 52.1 1.0 157.6 10.0 457.8 150.0 92.9 36.8 27.9 57.7 142.7 31.1 0.0 81.6 1.2 54.9 27.5 24.5 62.7 136.9 63.1 31.9 62.7 333.1 0.0 34.5 6.1 28.9 2.5 111.3 77.3 38.1 0.0 0.0 43.8 210.3 115.4 0.0 0.0 61.5 33.7 116.6 86.7 110.6 38.7 300.2 26.9 112.3 52.6 61.5 65.0 67.9 54.0 22.1 1.7 1.6 104.2 110.4 23.6 65.1 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORBS2 "ARGBP2, KIAA0777" ENSG00000154556 "Sorbin and SH3 domain containing 2" O94875 4 185585444-185956652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 575.3;thyroid gland: 277.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 557.8;Cone photoreceptor cells: 771.5;Excitatory neurons: 397.4;Rod photoreceptor cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 241.1;TIME: 133.1;WM-115: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.30e-2)" "unprognostic (5.09e-2)" "unprognostic (1.20e-1)" "prognostic favorable (6.07e-5)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" "unprognostic (8.30e-2)" "unprognostic (1.72e-1)" "prognostic favorable (3.10e-6)" "unprognostic (1.26e-1)" "unprognostic (2.42e-1)" "unprognostic (2.79e-3)" "unprognostic (2.51e-2)" 27.4 166.6 32.3 11.5 62.5 0.1 38.9 0.0 40.3 31.8 14.1 85.9 10.5 17.6 34.3 36.5 37.0 29.0 575.3 38.0 2.1 32.4 126.5 19.2 5.3 16.1 0.9 17.6 117.3 100.5 29.1 69.0 18.2 56.1 25.9 156.1 74.4 62.3 6.9 8.1 16.1 31.6 1.9 26.2 40.5 3.0 2.8 31.1 277.6 12.8 11.3 50.1 16.3 26.7 0.4 0.5 241.1 0.2 33.6 59.4 12.0 0.5 0.2 0.0 0.6 6.8 19.4 0.0 25.8 2.2 1.6 0.0 0.0 9.1 0.2 0.1 3.6 3.8 18.4 16.0 0.0 0.0 0.2 22.0 2.7 37.1 2.9 31.7 44.8 6.7 0.1 0.2 2.7 0.0 0.0 0.7 23.4 0.0 0.0 23.9 0.0 0.2 32.8 5.9 30.2 9.0 0.0 0.1 14.9 23.3 7.3 0.0 133.1 18.2 2.4 0.3 9.4 0.3 0.4 0.3 39.3 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 62.5 0.0 40.3 38.0 2.1 16.1 0.9 18.2 1.9 2.8 26.7 71.1 22.4 41.4 18.9 2.4 6.5 18.5 44.1 21.6 99.7 81.4 45.6 557.8 228.8 85.5 64.4 771.5 12.8 1.9 8.5 5.9 166.1 3.2 80.8 4.0 69.6 41.9 5.3 397.4 110.1 2.6 30.7 30.1 75.3 2.5 102.4 26.7 206.6 1.6 5.0 247.3 14.0 61.1 4.1 8.0 6.9 5.6 2.5 19.6 150.9 3.1 265.7 12.3 204.1 7.2 57.7 27.1 3.8 5.3 25.8 15.8 25.8 149.3 815.8 118.3 4.4 297.8 0.3 1.4 12.4 5.5 10.9 1.8 13.2 26.8 19.3 SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 107.1;Bipolar cells: 70.3;Excitatory neurons: 41.4;Muller glia cells: 33.0;Oligodendrocytes: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 7.6;HaCaT: 19.6;HMC-1: 14.5;RPMI-8226: 9.1;SiHa: 14.1;THP-1: 8.4;U-937: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" 2.4 1.1 13.4 3.4 18.3 1.7 1.6 11.6 15.9 8.5 0.0 4.5 1.4 4.7 3.8 2.2 3.3 3.6 2.0 12.1 11.3 9.0 4.6 4.4 0.8 18.6 17.6 5.8 0.7 0.0 2.7 0.2 14.7 5.2 1.1 12.9 1.0 2.4 1.1 1.8 2.6 6.2 11.3 0.4 1.6 1.6 14.1 3.1 3.1 1.2 1.2 3.0 3.7 22.9 0.8 1.1 1.3 0.2 0.1 0.0 0.0 0.2 0.1 1.6 0.4 0.2 0.6 0.0 7.6 5.0 1.3 19.6 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.3 0.2 0.0 14.5 0.2 4.3 6.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 0.0 0.9 0.0 1.6 9.1 0.2 0.0 0.8 0.7 14.1 0.0 0.0 0.8 0.0 8.4 0.0 4.9 1.4 0.0 0.1 0.0 0.0 0.0 1.6 8.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 18.3 11.6 15.9 12.1 11.3 18.6 17.6 14.7 11.3 14.1 22.9 0.1 3.2 11.3 107.1 0.0 0.1 0.3 4.6 0.0 70.3 0.1 2.4 2.0 0.0 6.9 5.5 0.0 0.0 0.3 0.0 0.0 0.2 2.2 0.4 0.4 0.3 0.0 0.0 41.4 0.0 0.0 5.0 0.0 0.9 0.0 5.4 0.4 1.6 0.2 1.7 24.3 0.0 2.0 0.3 0.0 11.6 12.8 0.4 1.8 8.4 0.1 33.0 1.0 8.0 76.2 1.1 0.0 7.9 0.1 0.4 0.4 1.4 2.0 2.7 0.0 0.9 1.0 0.1 0.3 0.0 0.4 0.0 0.3 1.5 0.0 0.6 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.8;Excitatory neurons: 247.4;Microglial cells: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 142.8;Daudi: 68.7;OE19: 93.5;RT4: 102.1;U-698: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" 7.0 6.1 29.1 24.4 39.1 47.4 13.9 49.5 35.5 44.4 0.0 17.3 11.6 5.4 8.9 5.4 40.1 7.3 2.4 33.8 39.7 19.0 58.2 10.4 21.1 40.3 46.8 9.0 8.0 10.4 16.8 2.3 47.0 20.8 16.9 20.3 21.8 25.4 1.7 3.4 18.1 4.5 45.3 21.8 10.3 5.1 38.8 17.0 13.5 4.0 23.0 15.7 6.6 79.1 1.3 8.1 7.3 1.1 0.0 0.0 7.4 0.4 2.4 0.3 0.0 11.9 142.8 68.7 8.5 1.8 10.5 47.4 9.1 7.0 0.1 0.0 2.6 0.0 10.3 16.8 0.1 29.6 0.1 0.0 7.6 0.0 25.8 4.0 0.0 8.7 0.0 0.7 0.0 9.7 7.1 15.3 8.8 93.5 10.8 7.7 0.4 1.6 15.8 102.1 5.1 1.5 15.2 21.5 0.0 16.0 21.0 9.5 0.3 0.1 4.9 1.0 0.0 0.0 0.0 139.8 0.1 38.6 0.4 44.3 15.9 59.1 22.1 6.9 29.3 1.9 24.6 20.0 6.6 5.1 23.1 20.8 125.7 20.9 9.4 16.4 19.3 21.2 29.1 39.1 49.5 35.5 33.8 39.7 40.3 46.8 47.0 45.3 38.8 79.1 1.6 6.4 23.3 160.9 20.7 4.5 42.3 23.3 18.2 68.8 44.5 22.0 12.3 18.6 36.8 79.1 387.8 0.4 130.1 132.1 0.0 10.3 1.2 21.6 2.9 10.3 6.1 8.8 247.4 0.7 0.7 5.8 14.3 24.7 12.0 20.6 34.6 114.5 39.1 50.5 80.1 54.6 40.7 62.4 16.9 5.0 77.9 67.0 3.6 404.7 97.5 28.0 146.2 74.9 86.0 6.4 81.1 57.9 28.6 36.1 168.6 1.0 15.6 31.2 0.0 19.5 10.3 2.9 18.8 20.8 2.4 0.4 60.2 32.7 42.2 33.4 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 117.8" "Cell type enriched" "Detected in some" 5 "Early spermatids: 1014.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041927: AB_10794162, HPA061302: AB_2684475" "unprognostic (2.48e-2)" "unprognostic (6.37e-4)" "unprognostic (6.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.09e-3)" "unprognostic (9.43e-6)" "unprognostic (6.67e-3)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (3.43e-1)" "unprognostic (2.88e-1)" "unprognostic (4.47e-1)" "unprognostic (2.01e-2)" 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.3 0.6 0.0 3.6 3.0 0.0 0.0 2.0 0.2 1.1 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.9 0.0 0.1 1.4 3.1 0.0 0.0 0.0 3.4 117.8 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.6 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1014.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 185.9 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 9.8 3.3 0.0 1.6 0.0 0.0 0.0 0.0 0.2 SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 63.5;fallopian tube: 49.0;testis: 96.3" "Cell type enhanced" "Detected in some" "Early spermatids: 228.6;Endometrial ciliated cells: 73.2;Respiratory ciliated cells: 266.4;Spermatocytes: 372.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "U-937: 105.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 11.1" HPA038440 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038440: AB_10671742" "unprognostic (5.02e-2)" "unprognostic (9.52e-2)" "unprognostic (8.94e-6)" "unprognostic (2.21e-1)" "unprognostic (2.51e-2)" "unprognostic (4.91e-3)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (3.10e-2)" "unprognostic (2.78e-4)" 0.0 0.0 4.2 0.0 4.0 0.4 1.7 1.9 1.4 1.7 63.5 0.0 0.0 0.2 0.4 0.0 49.0 0.0 0.1 3.3 5.0 0.3 0.1 7.0 0.1 17.6 16.1 0.1 0.3 1.8 14.6 0.0 9.9 1.0 0.0 5.8 0.0 0.0 0.0 0.3 0.0 0.0 16.3 0.0 0.0 96.3 6.4 0.4 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.9 2.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.8 0.2 0.0 105.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 4.2 4.0 1.9 1.4 3.3 5.0 17.6 16.1 9.9 16.3 6.4 10.1 0.0 0.0 4.8 0.0 0.1 0.1 0.1 14.0 0.0 0.2 0.5 0.3 0.6 0.0 24.5 0.0 0.0 0.1 0.2 0.1 1.9 0.3 228.6 73.2 0.4 0.2 0.0 0.0 7.1 0.0 0.0 0.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 3.1 0.0 16.2 0.0 0.2 51.4 5.0 0.5 1.8 4.7 0.0 0.3 0.0 0.5 6.0 0.4 0.0 4.9 0.3 1.8 0.0 1.4 266.4 1.2 0.0 0.0 3.7 372.6 4.8 0.0 0.1 0.0 0.5 0.1 0.0 0.1 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPATA13 "ARHGEF29, FLJ31208" ENSG00000182957 "Spermatogenesis associated 13" Q96N96 13 23979805-24307074 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 65.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 102.6;Oligodendrocytes: 206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 33.4;HDLM-2: 46.4" "HPA040185, HPA041208" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA040185: AB_10795521, HPA041208: AB_10794193" "unprognostic (8.80e-2)" "unprognostic (9.32e-3)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (4.35e-1)" "unprognostic (2.66e-3)" "unprognostic (6.23e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (2.00e-2)" "unprognostic (2.76e-3)" "unprognostic (9.15e-3)" "unprognostic (1.78e-1)" "unprognostic (4.21e-1)" "prognostic favorable (1.16e-4)" 6.9 14.3 17.7 18.8 31.6 31.2 14.4 26.2 31.5 10.6 34.2 11.0 11.9 9.4 14.2 3.7 9.9 12.1 8.6 19.7 23.5 21.8 24.4 20.4 23.4 42.3 31.8 14.4 38.4 6.5 9.6 10.6 37.3 14.6 12.4 4.8 8.2 6.6 2.5 7.8 13.3 7.5 25.7 65.3 17.9 6.4 29.6 18.6 12.9 6.4 16.6 9.6 5.2 40.1 3.1 5.0 25.6 3.2 0.9 2.1 1.0 7.7 33.4 3.9 3.3 6.5 13.2 20.4 4.1 7.0 2.0 5.7 7.4 2.3 9.7 46.4 8.9 4.9 4.6 7.5 1.2 7.9 3.7 2.8 0.3 4.2 2.4 3.4 6.5 10.7 0.0 16.7 4.1 11.2 14.6 2.7 8.4 21.5 6.4 12.5 9.9 11.0 17.3 9.9 9.3 7.1 1.5 16.3 15.0 5.5 2.3 4.5 7.6 5.1 4.0 0.4 5.5 3.8 0.1 0.0 4.4 7.5 24.4 5.0 6.4 0.0 33.6 8.4 26.2 2.6 28.6 35.3 4.7 2.0 30.1 31.3 39.2 20.4 10.6 5.2 29.8 13.3 17.7 31.6 26.2 31.5 19.7 23.5 42.3 31.8 37.3 25.7 29.6 40.1 9.0 3.2 23.9 61.0 8.6 5.4 3.2 2.5 4.6 3.2 39.5 17.9 5.3 0.0 17.8 14.7 0.0 1.3 18.6 27.4 3.9 25.3 10.8 58.3 12.9 29.0 32.3 6.3 9.2 15.8 14.1 12.5 51.0 102.6 70.2 4.9 0.0 0.0 10.1 0.0 11.1 24.9 4.1 0.0 8.5 6.3 7.5 29.8 5.4 62.8 15.2 14.1 66.9 19.6 206.5 13.5 32.0 7.5 2.8 23.8 25.0 7.2 40.5 0.8 0.0 21.9 8.2 2.2 2.2 4.6 6.1 22.3 37.8 34.5 23.7 17.0 SPATC1L C21orf56 ENSG00000160284 "Spermatogenesis and centriole associated 1 like" Q9H0A9 21 46161148-46184476 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.9" "Group enriched" "Detected in many" 5 "Early spermatids: 208.9;Late spermatids: 472.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 3.7;cerebral cortex: 4.8;hippocampal formation: 2.9" "Immune cell enhanced" "Detected in many" "eosinophil: 36.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 37.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018979, HPA019165, HPA029394" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane, Cytosol" "HPA018979: AB_1845696, HPA019165: AB_1845697, HPA029394: AB_10601148" "unprognostic (1.46e-2)" "unprognostic (3.88e-2)" "unprognostic (3.95e-2)" "unprognostic (4.86e-2)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.56e-2)" "unprognostic (2.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-2)" "unprognostic (2.58e-1)" 7.6 23.4 4.2 1.0 3.7 1.3 8.5 0.0 4.8 11.4 0.0 9.7 1.3 9.8 0.6 7.7 6.8 1.4 11.5 2.9 0.6 7.3 1.3 5.9 1.6 0.4 0.1 13.9 11.3 1.6 14.2 1.1 0.1 32.5 0.7 0.3 6.7 2.5 5.6 10.5 6.9 0.8 0.0 8.4 8.3 48.9 0.9 1.0 6.3 0.8 1.0 9.8 11.7 0.1 2.9 0.0 3.6 6.7 2.0 4.7 1.9 4.1 2.2 2.2 1.7 0.0 1.8 9.0 8.0 5.0 2.6 0.5 0.0 3.2 0.6 8.3 6.6 21.6 1.3 5.0 0.1 0.0 8.5 5.0 1.5 0.0 0.0 4.2 7.2 10.1 37.8 13.2 3.1 5.7 7.0 2.5 15.0 4.0 18.0 15.4 4.9 10.0 3.4 0.8 1.1 6.9 3.2 1.7 8.6 2.5 5.6 8.3 0.4 6.5 8.0 9.3 6.3 21.9 12.6 6.6 8.6 11.9 6.1 1.5 5.7 36.1 4.3 6.8 5.6 7.6 6.2 5.9 8.6 7.6 9.7 9.2 0.3 6.6 4.7 7.2 7.0 3.6 4.2 3.7 0.0 4.8 2.9 0.6 0.4 0.1 0.1 0.0 0.9 0.1 20.5 0.0 0.0 3.6 13.5 23.6 11.6 21.4 18.2 6.8 11.9 14.6 1.9 12.8 6.9 3.7 0.0 3.4 10.1 7.7 15.6 16.8 208.9 6.3 14.6 15.4 60.4 12.8 2.6 20.5 17.7 18.1 13.7 8.8 0.0 18.8 14.6 0.6 13.7 3.3 2.0 16.4 8.2 8.8 24.4 472.3 32.3 9.9 28.4 1.0 5.9 5.8 6.2 3.0 3.1 17.8 6.6 31.6 28.0 24.1 6.8 13.4 2.8 3.1 19.7 12.0 14.0 17.8 14.7 17.0 40.1 3.1 11.7 4.0 18.3 8.1 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Cardiomyocytes: 61.5;Late spermatids: 39.6;Sertoli cells: 46.0;Smooth muscle cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 45.9;U-87 MG: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 16.1 6.8 16.8 7.7 18.7 0.0 15.3 15.5 20.7 75.5 9.7 174.8 5.3 89.5 6.2 15.6 70.0 7.3 48.5 19.8 14.5 4.1 1.3 8.7 0.6 16.1 15.8 21.9 3.4 4.4 34.3 4.5 14.6 58.8 3.8 1.0 10.0 25.5 118.0 7.8 31.9 23.1 15.3 2.4 48.1 5.4 15.3 0.5 5.9 21.7 0.2 87.7 42.1 15.6 6.1 0.5 3.1 4.9 1.6 4.7 1.8 13.1 8.5 8.6 6.4 4.5 1.9 0.0 4.5 9.7 4.3 7.2 2.5 3.1 3.4 0.0 1.7 0.0 6.1 0.3 2.1 0.0 0.5 13.2 4.6 7.8 1.9 45.9 0.0 3.2 3.5 0.0 6.1 1.6 0.1 18.8 6.5 0.0 2.4 2.8 7.0 1.1 8.5 0.0 3.4 15.1 0.6 0.0 0.3 14.3 0.3 0.2 0.0 20.6 21.3 2.4 21.1 0.4 0.0 0.2 23.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 18.7 15.5 20.7 19.8 14.5 16.1 15.8 14.6 15.3 15.3 15.6 2.4 0.0 2.2 45.7 0.4 3.2 6.0 1.3 2.8 5.3 10.3 14.6 61.5 4.3 0.1 1.8 2.1 0.6 1.4 4.1 0.0 1.5 21.8 0.9 3.6 2.2 6.7 2.7 20.5 1.2 0.9 10.0 3.6 1.3 0.0 1.0 5.7 3.1 1.1 5.0 20.9 4.1 0.0 5.6 1.9 39.6 10.5 1.6 3.6 4.7 1.4 8.4 0.0 5.0 1.0 0.2 3.2 18.8 0.9 6.5 8.5 4.3 0.1 0.9 46.0 17.1 32.4 11.6 3.7 0.2 1.4 1.4 1.2 0.4 3.5 5.3 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPNS3 "MGC29671, SLC62A3" ENSG00000182557 "Sphingolipid transporter 3 (putative)" Q6ZMD2 17 4433940-4488208 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 31.2" "Cell type enhanced" "Detected in many" "dendritic cells: 30.9;Langerhans cells: 16.4;Proximal tubular cells: 51.8;T-cells: 23.7" "Cancer enhanced" "Detected in many" "renal cancer: 2.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "eosinophil: 354.8;plasmacytoid DC: 127.7" "Group enriched" "Detected in many" 37 "dendritic cells: 127.7;granulocytes: 354.8" "Group enriched" "Detected in some" 4 "JURKAT: 29.5;NB-4: 46.8;THP-1: 35.5;U-937: 22.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023928 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA023928: AB_1844393" "unprognostic (4.39e-2)" "unprognostic (8.10e-5)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.94e-4)" "unprognostic (2.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.81e-2)" "unprognostic (6.46e-2)" "unprognostic (1.37e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (6.18e-2)" "unprognostic (6.57e-2)" "unprognostic (4.13e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.3 1.4 0.2 31.2 0.3 0.4 0.4 0.2 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.7 0.2 0.2 0.7 0.2 0.1 0.2 2.0 0.8 0.4 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.9 0.3 0.0 0.3 0.7 0.1 0.6 2.1 0.3 0.0 0.5 3.6 0.0 0.0 1.1 0.3 0.0 0.7 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 2.4 0.0 0.0 8.1 46.8 0.0 0.2 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.6 0.0 22.1 0.0 0.3 6.5 354.8 1.1 1.3 0.7 0.2 0.0 1.5 47.6 0.3 0.4 1.7 1.0 0.2 0.1 127.7 0.0 6.2 0.3 0.2 0.4 0.4 0.2 0.7 0.8 0.4 0.5 0.6 0.5 0.7 0.5 3.2 1.1 0.0 4.3 1.3 0.1 0.4 0.0 0.0 1.0 0.8 0.8 1.5 1.6 0.0 0.0 0.3 30.9 0.5 3.9 2.0 1.1 0.8 0.0 0.6 0.0 4.8 0.9 0.0 6.1 0.3 2.0 0.1 0.0 0.0 0.7 0.3 1.4 0.0 0.8 2.1 6.1 5.5 16.4 2.6 0.0 9.8 1.8 3.7 6.7 0.0 11.3 0.0 0.1 1.1 1.4 0.0 0.6 0.5 10.9 51.8 5.0 0.0 0.0 0.3 0.6 0.0 0.3 0.2 0.4 0.3 23.7 0.0 2.5 2.1 SPOP "BTBD32, TEF2" ENSG00000121067 "Speckle type BTB/POZ protein" O43791 17 49598884-49678163 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (8.83e-2)" "unprognostic (3.23e-1)" "unprognostic (2.15e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (1.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.24e-3)" "unprognostic (7.67e-2)" "unprognostic (2.81e-1)" "unprognostic (3.45e-2)" "unprognostic (1.10e-2)" "unprognostic (3.29e-1)" 32.3 26.8 33.4 28.7 37.6 13.6 30.2 49.8 39.8 45.7 35.9 92.2 27.4 50.1 35.8 56.9 42.2 29.8 41.0 36.1 37.3 29.5 37.1 33.1 38.9 33.1 34.0 40.9 25.1 30.9 22.7 32.5 34.6 64.8 39.2 38.2 32.8 81.7 57.2 26.5 34.0 77.8 31.8 32.8 35.0 17.0 38.4 43.6 35.2 52.4 42.8 46.7 30.6 42.8 33.7 30.9 40.9 18.3 49.0 51.8 28.0 44.1 47.6 57.6 62.8 71.1 36.8 56.4 84.2 41.3 38.5 29.2 49.3 29.1 68.8 111.4 57.6 70.6 38.9 47.8 54.6 45.9 50.3 39.0 41.4 42.9 46.2 43.1 60.9 39.6 73.3 54.2 42.4 33.3 79.2 44.0 11.4 80.9 46.3 48.8 64.5 79.9 32.9 21.0 65.2 26.7 29.7 14.1 37.2 22.5 54.2 45.8 55.4 65.9 41.0 49.9 39.5 52.3 51.7 50.6 37.6 41.0 32.9 145.3 71.2 93.0 61.3 68.7 59.8 76.4 66.0 68.9 91.8 80.2 98.2 78.9 107.9 74.9 88.8 67.9 63.9 92.4 33.4 37.6 49.8 39.8 36.1 37.3 33.1 34.0 34.6 31.8 38.4 42.8 54.5 48.1 41.6 80.6 59.2 42.8 36.2 26.7 34.7 72.7 44.5 38.7 51.6 35.8 30.4 29.5 43.8 23.3 47.3 25.9 29.4 36.5 24.4 30.3 38.8 57.5 51.5 53.2 50.5 28.2 23.3 55.9 18.8 28.4 31.0 39.2 66.8 47.3 38.5 75.7 50.1 46.2 30.5 62.2 59.4 8.9 56.2 49.0 39.2 45.9 67.7 100.2 33.0 54.3 49.3 25.6 30.5 73.4 61.4 30.6 40.1 29.6 32.4 58.7 72.3 37.1 59.2 36.6 45.8 28.2 43.9 36.1 46.7 50.1 33.3 22.8 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 147.2;Proximal tubular cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" 1.5 3.7 1.6 1.6 1.4 2.8 3.1 3.2 1.9 2.0 0.7 2.5 2.0 2.0 3.0 3.1 2.0 1.5 3.3 1.4 1.6 3.7 20.5 1.4 1.8 0.8 0.8 2.4 6.0 2.5 3.7 1.2 1.0 2.6 3.2 3.4 2.7 1.7 4.1 2.4 2.2 1.7 0.5 2.3 2.5 1.5 1.3 1.4 2.7 5.1 1.7 2.3 2.1 1.2 2.1 2.7 2.3 1.8 2.0 1.3 3.1 1.7 1.7 3.5 2.1 2.5 3.6 2.6 2.2 2.2 2.4 3.5 2.0 2.9 2.2 1.3 4.1 3.8 3.1 3.8 1.9 2.6 3.7 2.9 1.9 2.5 2.1 1.9 3.6 1.8 2.1 11.0 3.0 3.4 1.3 1.9 1.5 2.4 3.1 1.6 1.7 5.4 3.8 2.6 2.3 1.1 3.3 3.9 2.6 1.4 6.6 0.8 1.7 1.5 2.8 2.2 1.4 1.8 1.1 0.9 1.2 2.2 1.9 1.0 1.0 0.5 0.7 0.7 0.8 1.0 0.7 0.7 0.9 1.0 0.7 0.7 0.7 1.2 0.9 1.3 0.3 0.7 1.6 1.4 3.2 1.9 1.4 1.6 0.8 0.8 1.0 0.5 1.3 1.2 4.4 0.0 7.4 2.0 7.9 4.8 16.2 24.8 10.2 13.2 14.1 12.7 17.7 18.6 16.2 22.0 16.7 38.3 5.8 17.3 54.8 26.6 1.4 4.0 7.5 8.9 17.5 19.1 0.9 21.4 24.3 8.1 14.8 9.8 10.2 10.7 10.0 147.2 20.8 16.8 1.6 14.6 28.5 12.2 2.3 1.1 9.0 6.4 5.4 1.9 11.1 10.2 8.2 2.0 2.2 18.5 10.1 10.5 6.3 10.8 19.5 101.5 5.9 17.8 0.0 8.1 8.6 5.1 10.2 22.2 5.3 36.0 4.4 30.2 16.4 19.8 SPSB4 SSB-4 ENSG00000175093 "SplA/ryanodine receptor domain and SOCS box containing 4" Q96A44 3 141051347-141148611 "Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.9;pancreas: 7.0;pituitary gland: 3.0;testis: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 23.6;Late spermatids: 11.7;Oligodendrocyte precursor cells: 41.7;Spermatocytes: 22.1" "Group enriched" "Detected in some" 5 "glioma: 4.6;testis cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 12.5;NTERA-2: 3.5;RH-30: 4.2;SH-SY5Y: 3.6;U-2 OS: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062793 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA062793: AB_2732689" "unprognostic (5.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.72e-4)" "unprognostic (7.49e-2)" "unprognostic (6.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-3)" "unprognostic (2.30e-2)" "unprognostic (2.46e-4)" "unprognostic (9.80e-3)" 0.3 0.3 0.5 0.0 0.9 0.0 0.1 0.8 1.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 2.0 0.3 0.0 0.4 0.0 2.8 2.1 0.0 7.0 0.2 3.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 1.5 1.1 0.0 2.9 1.1 0.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 12.5 0.2 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.9 0.0 3.5 0.0 0.0 0.0 4.2 0.6 0.0 0.0 1.1 3.6 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.8 1.2 0.3 2.0 2.8 2.1 1.6 1.5 1.1 0.9 0.4 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.1 0.1 0.0 0.0 2.8 0.5 0.0 3.2 0.0 0.0 0.0 0.4 0.4 0.1 0.2 0.0 5.6 0.0 0.0 5.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 0.3 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.4 22.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favorable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" 17.6 12.2 14.6 12.6 26.7 33.7 18.3 24.0 19.4 15.2 9.9 18.5 14.5 10.5 7.6 22.8 14.2 11.8 6.7 15.3 18.1 17.6 7.7 13.1 12.0 30.7 21.5 10.4 5.7 10.7 6.2 20.4 31.5 8.4 19.8 14.2 13.7 8.8 3.9 12.2 17.4 11.6 25.3 19.6 20.4 5.0 21.7 10.3 10.9 6.1 13.3 15.0 10.8 52.7 28.9 18.5 14.1 15.5 14.3 17.8 23.7 41.7 30.8 28.2 29.3 23.7 62.3 28.8 10.4 42.7 14.5 34.7 38.1 23.7 42.5 12.6 11.0 82.5 13.4 14.3 12.1 8.4 25.8 11.7 11.4 18.4 20.4 16.3 40.6 19.4 16.2 13.5 16.2 24.9 22.2 28.7 9.2 45.4 16.8 23.5 14.3 10.0 32.9 63.4 13.6 17.1 15.0 50.3 15.8 24.7 61.8 15.3 25.9 25.7 18.2 9.6 9.7 7.6 13.4 19.1 17.3 29.4 14.8 18.3 31.3 27.1 6.1 24.2 5.7 6.7 5.1 6.8 31.2 7.9 3.5 5.8 19.1 17.7 31.8 11.1 6.0 13.4 14.6 26.7 24.0 19.4 15.3 18.1 30.7 21.5 31.5 25.3 21.7 52.7 125.1 28.9 27.3 24.8 27.3 32.4 28.3 27.0 15.4 15.7 24.3 18.4 8.9 15.7 30.7 47.8 35.5 11.9 28.3 37.6 1.9 24.0 1.6 44.1 36.0 53.1 13.2 51.3 31.2 16.1 12.3 18.9 43.3 36.0 51.3 37.2 68.2 7.2 25.1 5.0 29.5 39.3 20.3 75.9 19.8 1.7 14.6 66.2 19.6 83.4 51.3 8.8 32.0 59.3 164.0 35.0 30.4 15.8 11.0 27.0 28.4 8.8 33.5 20.0 32.9 10.5 25.5 7.3 19.0 37.7 29.1 6.6 23.3 14.6 33.0 60.0 SRF MCM1 ENSG00000112658 "Serum response factor" P11831 6 43171269-43181506 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.6;Enteroendocrine cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001819, CAB005416" Supported Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB005416: AB_2255249, HPA001819: AB_1079928" "unprognostic (1.44e-3)" "unprognostic (1.09e-1)" "unprognostic (5.39e-3)" "unprognostic (2.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-2)" "unprognostic (4.60e-2)" "unprognostic (9.84e-2)" "unprognostic (4.28e-2)" "unprognostic (2.21e-2)" "unprognostic (6.72e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.31e-2)" "unprognostic (1.59e-1)" "unprognostic (5.10e-2)" "unprognostic (1.97e-2)" 29.7 16.7 16.0 27.0 15.3 27.3 24.7 12.4 18.7 31.2 12.4 82.6 13.4 69.3 12.4 33.3 49.2 26.5 61.2 17.6 11.6 17.0 20.2 28.6 21.4 14.1 12.7 27.6 21.8 18.5 18.8 17.4 11.8 38.7 14.9 8.8 16.8 45.5 55.4 21.2 29.3 48.2 12.1 22.3 37.0 12.6 13.4 21.4 23.9 32.7 16.5 54.5 25.7 16.7 38.4 15.0 34.2 22.6 19.8 16.2 50.2 34.2 28.0 29.0 17.9 40.4 11.1 48.1 30.5 36.7 36.7 30.4 35.0 30.2 25.5 53.5 34.4 43.6 30.7 40.2 37.7 41.2 50.9 27.8 32.3 44.8 32.7 27.4 24.5 41.0 31.6 36.8 22.2 41.1 51.2 35.9 23.8 85.7 18.3 38.7 34.9 17.3 21.3 24.5 20.0 18.1 28.0 21.1 34.2 26.2 21.7 75.6 29.9 34.2 26.4 33.4 59.5 25.4 22.6 80.6 21.4 29.2 23.5 0.4 0.4 0.8 0.8 0.8 0.6 0.5 0.4 0.6 0.5 0.5 0.3 0.6 1.2 0.3 0.6 1.0 0.6 0.3 16.0 15.3 12.4 18.7 17.6 11.6 14.1 12.7 11.8 12.1 13.4 16.7 17.1 38.5 22.5 3.9 8.8 78.0 64.3 22.6 38.1 5.7 64.0 52.1 89.6 18.6 21.7 11.0 20.9 9.7 9.4 29.8 0.0 13.6 4.7 23.8 24.6 17.5 102.2 20.2 4.9 20.0 22.6 17.0 18.3 29.5 7.6 20.6 17.2 50.6 12.7 10.1 3.5 39.1 8.2 11.3 18.8 1.1 12.5 11.6 24.9 0.0 8.0 12.5 5.2 1.5 2.8 21.5 19.6 29.0 6.5 17.8 11.1 3.8 20.3 7.5 13.1 23.6 21.8 5.2 3.3 28.7 66.9 12.2 10.5 8.9 25.6 30.2 SRL SAR ENSG00000185739 Sarcalumenin Q86TD4 16 4189374-4242080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 41 "heart muscle: 280.1;skeletal muscle: 510.3;tongue: 382.3" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 247.3" "Group enriched" "Detected in some" 5 "head and neck cancer: 1.5;thyroid cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HSkMC: 4.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "basal ganglia: 5.3" "HPA041535, HPA045520" Enhanced "Intracellular and membrane" NA NA 230000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041535: AB_2677538, HPA045520: AB_2679358" "unprognostic (1.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (8.11e-2)" "unprognostic (2.04e-7)" "unprognostic (1.41e-1)" "unprognostic (8.28e-2)" "unprognostic (7.40e-4)" "unprognostic (4.91e-2)" "unprognostic (8.70e-2)" "unprognostic (7.78e-4)" "unprognostic (3.33e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-3)" "unprognostic (1.68e-4)" 3.0 0.4 1.0 1.2 1.0 0.2 1.7 1.0 1.5 3.2 0.8 1.3 0.4 3.0 2.3 9.6 3.1 1.8 280.1 0.8 1.2 1.4 0.4 1.2 0.7 1.2 1.3 1.3 0.6 0.2 0.5 1.3 1.1 5.6 1.1 8.5 6.4 2.6 510.3 1.1 1.7 3.4 1.0 2.2 1.1 1.0 1.1 1.7 2.3 382.3 1.1 1.4 1.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 1.0 1.0 1.0 1.5 0.8 1.2 1.2 1.3 1.1 1.0 1.1 1.0 0.5 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.0 247.3 0.0 0.0 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 0.0 0.0 0.4 0.0 0.0 8.5 0.0 0.1 0.0 0.2 2.9 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.3 0.0 1.8 0.1 0.0 1.0 0.0 1.2 0.0 1.0 0.3 0.1 0.0 3.8 0.0 0.3 0.0 0.2 0.0 12.1 6.6 5.5 15.4 0.1 0.2 0.0 0.4 0.0 0.1 0.4 0.0 0.1 SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 256.9;Granulosa cells: 138.9;Hepatic stellate cells: 418.7;Leydig cells: 110.3;Peritubular cells: 95.2" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cell line enhanced" "Detected in many" "ASC diff: 3742.4;ASC TERT1: 827.3;HSkMC: 1258.3;HUVEC TERT2: 803.2" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" 215.2 37.2 8.2 22.4 12.8 0.1 148.0 17.8 5.9 48.6 5.2 83.0 7.9 56.1 39.6 36.6 113.4 58.1 93.3 7.0 16.7 7.4 17.7 46.6 5.0 13.2 14.2 21.4 23.9 2.7 4.6 88.9 15.4 18.3 24.8 1.6 22.9 15.3 15.6 29.2 52.6 52.9 15.1 1.7 42.5 6.7 13.8 19.2 59.1 13.6 5.3 103.8 42.9 15.4 0.3 5.0 12.1 0.2 3742.4 827.3 0.9 35.3 67.8 11.9 20.2 0.5 3.6 0.1 0.3 74.3 119.9 1.9 2.0 30.8 9.8 0.2 13.8 0.1 1.0 0.4 167.8 3.0 0.4 1258.3 2.6 114.9 58.3 132.8 803.2 1.4 0.1 0.2 130.1 1.7 0.5 0.1 10.2 1.8 26.2 0.0 43.5 6.4 0.8 2.3 2.3 2.3 1.7 0.1 170.1 31.2 0.0 0.4 349.1 82.2 42.3 108.8 103.7 0.0 0.1 0.1 239.0 3.1 106.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.0 0.1 8.2 12.8 17.8 5.9 7.0 16.7 13.2 14.2 15.4 15.1 13.8 15.4 28.7 3.2 1.3 17.0 0.6 15.3 2.2 2.8 7.4 0.4 2.9 8.6 14.2 0.0 0.2 1.8 0.0 3.6 2.1 2.5 0.0 0.3 0.7 1.1 35.1 67.2 0.0 2.7 1.9 0.4 5.4 256.9 1.5 0.8 0.0 138.9 418.7 2.5 6.1 0.0 2.7 5.8 0.0 11.4 15.2 4.9 110.3 1.6 74.7 1.0 0.0 0.2 0.0 2.5 0.3 0.8 1.8 95.2 0.2 1.6 0.4 0.2 0.0 0.4 26.3 4.8 54.6 0.7 2.3 1.7 7.2 7.1 1.9 21.4 0.5 0.8 SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: AB_2680020" "unprognostic (4.09e-3)" "unprognostic (1.90e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "prognostic favorable (7.03e-4)" "unprognostic (6.55e-2)" "unprognostic (4.51e-2)" "unprognostic (2.62e-2)" "unprognostic (2.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" 21.0 17.1 27.6 18.5 28.6 33.9 21.9 28.8 37.1 19.8 26.7 17.5 19.0 12.6 17.8 21.2 15.7 10.4 18.7 28.2 28.4 24.5 32.4 19.6 35.4 28.2 27.8 19.1 21.6 13.5 25.1 9.9 28.3 35.9 13.6 13.7 19.1 8.6 16.2 24.9 25.6 7.4 28.4 31.6 22.7 10.1 27.8 23.6 20.4 11.0 30.2 19.4 18.5 31.5 32.3 14.0 29.0 26.4 34.9 27.8 17.3 20.6 22.4 28.7 32.2 27.1 29.1 43.3 18.2 13.6 31.6 17.9 33.9 28.0 30.9 21.7 40.5 46.9 28.9 45.3 25.4 62.5 36.2 22.1 17.7 23.7 21.9 20.6 31.4 39.1 43.2 65.4 23.1 29.3 44.8 76.4 45.9 42.7 34.2 23.6 20.6 61.2 32.3 38.2 16.2 23.0 17.6 27.2 29.8 30.2 35.8 57.4 19.5 18.0 29.0 42.8 38.0 46.5 76.3 73.5 26.3 66.1 17.0 60.4 56.4 84.9 88.4 66.0 121.0 120.3 116.3 106.2 62.1 104.3 99.5 101.1 75.8 83.0 50.9 74.5 139.2 90.4 27.6 28.6 28.8 37.1 28.2 28.4 28.2 27.8 28.3 28.4 27.8 31.5 39.3 12.8 16.7 5.5 96.3 107.1 70.1 101.5 91.0 16.2 78.6 77.8 19.3 42.9 46.1 27.6 8.4 57.1 102.9 39.2 56.7 43.4 4.3 47.0 37.9 37.0 55.1 67.3 13.6 49.2 75.8 39.0 39.8 71.9 45.7 39.6 32.5 61.0 66.8 23.5 11.2 51.1 79.3 38.6 51.2 3.7 34.5 43.0 51.6 6.5 69.3 38.1 88.6 3.0 25.8 50.6 58.9 15.8 72.4 75.6 121.4 85.2 28.2 26.8 13.1 26.4 32.5 19.4 24.7 84.5 138.1 37.4 103.2 34.5 53.7 99.2 SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81413021-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 281.7;Excitatory neurons: 263.4;Inhibitory neurons: 350.0;Microglial cells: 339.2;Oligodendrocytes: 340.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 136.8;MOLT-4: 132.4;REH: 196.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB020834: , HPA068605: AB_2732116, HPA071780: " "unprognostic (4.62e-2)" "unprognostic (1.96e-3)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.78e-3)" "unprognostic (2.36e-3)" "unprognostic (6.01e-2)" "unprognostic (1.01e-2)" "unprognostic (3.04e-3)" "unprognostic (6.56e-2)" "unprognostic (9.81e-2)" "unprognostic (4.39e-3)" 28.8 12.7 25.9 13.0 27.9 14.0 26.5 37.0 26.1 31.2 24.1 29.7 5.7 29.1 30.2 24.4 29.9 16.2 31.8 24.1 34.2 12.8 3.3 16.2 19.8 25.0 33.2 37.1 11.2 47.3 28.0 13.7 27.7 19.2 12.9 53.3 20.8 21.3 23.6 27.2 15.5 29.8 26.2 12.5 17.8 7.9 31.3 96.4 17.7 22.2 24.3 25.7 26.1 27.2 3.8 6.8 85.1 48.8 48.0 72.6 5.2 18.1 16.4 16.5 16.9 0.3 7.1 60.8 1.2 21.3 8.2 0.4 23.6 9.7 15.9 26.1 10.1 12.8 14.6 0.3 27.1 6.4 32.5 74.8 82.1 2.8 15.9 35.6 7.1 136.8 8.4 29.2 17.9 8.7 132.4 10.7 11.7 0.1 3.8 196.2 19.3 47.2 8.8 3.3 44.2 39.7 19.1 21.1 6.6 34.3 31.1 18.1 4.9 6.5 10.4 12.3 4.9 30.4 25.1 101.6 21.8 11.3 4.4 60.4 19.0 61.1 5.0 17.5 8.0 23.9 16.2 9.3 18.3 33.6 31.3 11.1 27.9 61.3 29.6 5.9 7.8 18.7 25.9 27.9 37.0 26.1 24.1 34.2 25.0 33.2 27.7 26.2 31.3 27.2 43.7 9.6 18.6 281.7 39.0 34.9 40.3 44.3 122.9 75.0 25.1 38.1 45.3 12.8 34.4 29.5 27.1 7.7 12.5 4.1 17.6 14.0 5.9 25.2 27.3 21.4 15.0 29.7 263.4 10.0 3.7 48.6 10.2 22.0 25.3 5.4 23.9 2.3 20.5 42.1 350.0 5.4 61.1 17.0 21.7 4.2 37.9 29.9 35.6 339.2 15.6 122.4 5.2 185.0 340.2 6.1 13.6 48.5 14.9 14.9 2.5 4.5 34.1 49.3 52.6 48.9 59.4 10.0 29.8 60.3 36.2 7.4 23.9 9.9 4.4 27.3 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 269.0;Inhibitory neurons: 255.2;Microglial cells: 254.8;Oligodendrocytes: 547.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 134.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "CAB017189: , HPA057099: AB_2683336" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 15.6 9.5 11.7 22.5 13.1 62.8 10.7 12.8 16.3 7.1 3.6 13.0 8.3 7.3 8.9 12.7 8.2 8.9 19.4 13.1 23.2 15.1 13.6 21.4 29.0 19.0 14.4 3.9 14.6 6.2 7.1 10.4 18.5 6.3 10.9 8.1 10.7 4.5 91.5 14.4 20.7 7.9 11.4 28.3 15.5 28.2 16.3 28.9 13.9 35.6 24.8 9.0 8.7 24.5 25.8 19.0 12.6 10.8 36.1 24.7 8.8 12.3 12.9 19.6 19.2 12.9 9.0 22.1 18.8 14.1 12.6 31.0 14.8 17.1 22.4 7.1 28.1 14.9 21.2 17.4 16.6 16.7 30.7 30.4 12.3 20.6 13.4 9.7 47.3 36.2 9.9 16.8 13.7 7.3 74.9 15.5 9.4 9.3 11.5 37.9 31.9 37.0 35.7 20.3 20.6 32.3 18.0 18.6 36.6 16.3 12.6 19.4 25.6 12.6 26.3 23.5 16.1 26.9 20.0 53.8 16.4 13.1 12.3 47.2 15.2 134.8 10.4 20.2 8.5 21.3 11.6 11.1 12.7 22.4 11.5 8.7 91.6 4.6 36.7 7.7 16.4 6.5 11.7 13.1 12.8 16.3 13.1 23.2 19.0 14.4 18.5 11.4 16.3 24.5 19.6 9.6 38.5 81.6 137.0 39.6 12.3 20.6 27.9 12.4 22.2 19.2 28.2 12.8 23.2 16.5 27.1 20.4 68.7 54.3 25.4 14.9 108.4 27.9 10.1 26.9 35.4 27.8 269.0 35.5 26.4 22.2 33.1 32.5 12.6 6.0 19.6 26.9 22.3 20.2 255.2 34.8 14.2 120.2 31.3 174.4 12.2 75.9 35.6 254.8 83.6 9.2 82.4 184.0 547.9 40.3 38.6 8.2 49.4 12.9 64.5 63.1 18.4 22.9 6.6 34.4 17.0 80.9 16.7 37.6 36.2 18.2 65.8 14.2 21.6 30.2 SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 140.8;Leydig cells: 185.8;Peritubular cells: 267.4;Skeletal myocytes: 139.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Group enriched" "Detected in many" 4 "ASC diff: 24.4;hTERT-RPE1: 91.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" 21.3 10.7 18.0 6.4 26.5 0.1 20.1 26.2 15.4 39.5 8.6 21.2 4.4 23.9 17.8 18.3 25.2 21.9 46.0 16.1 30.1 6.1 1.4 8.9 7.0 26.5 29.1 33.8 8.0 3.2 3.8 4.6 27.9 22.4 12.7 2.9 9.4 34.4 60.7 4.4 7.7 24.3 31.5 8.7 7.7 8.3 21.5 8.7 17.1 79.0 12.1 19.2 15.4 38.4 0.8 1.6 4.0 0.0 24.4 14.5 0.2 6.9 10.8 1.1 3.1 0.1 9.5 0.0 1.8 11.0 6.0 3.0 0.0 0.5 2.1 0.1 0.0 0.0 0.1 0.0 2.9 0.1 0.0 9.3 1.0 3.5 0.8 91.6 0.4 0.0 0.0 0.1 8.4 1.9 0.6 1.9 7.9 0.6 2.7 0.3 10.7 3.2 2.4 8.3 0.4 6.3 2.7 0.6 7.0 4.0 0.9 0.3 3.0 2.5 1.8 3.4 1.8 0.3 1.2 0.2 5.3 0.0 8.6 0.0 0.0 2.7 0.0 0.0 0.5 57.4 0.0 0.0 0.1 16.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.7 18.0 26.5 26.2 15.4 16.1 30.1 26.5 29.1 27.9 31.5 21.5 38.4 10.8 3.2 3.2 39.2 30.7 13.6 23.1 21.6 30.1 2.1 21.8 89.2 95.4 10.0 14.8 18.4 0.0 74.0 1.4 36.0 5.9 11.4 4.0 12.4 52.1 10.2 4.9 1.3 3.5 7.1 7.5 140.8 3.6 6.0 0.0 10.7 9.7 0.2 15.3 6.7 5.8 10.1 0.0 0.6 11.1 5.8 185.8 6.6 19.6 18.7 18.6 41.2 0.0 41.7 18.4 2.8 7.3 267.4 41.2 19.4 0.6 3.1 7.9 2.7 39.5 139.9 56.3 0.7 3.8 7.7 7.1 27.8 2.1 30.7 7.7 24.7 ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643786 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 61.1;intestine: 195.9;stomach 1: 64.9" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 801.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 8.9;naive CD4 T-cell: 3.4" "Lineage enriched" "Detected in single" 32 "T-cells: 8.9" "Group enriched" "Detected in some" 4 "K-562: 65.5;OE19: 107.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 3500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: AB_1857529" "unprognostic (4.59e-2)" "unprognostic (8.60e-3)" "unprognostic (5.32e-3)" "unprognostic (1.86e-3)" "unprognostic (6.31e-3)" "prognostic favorable (2.54e-5)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.58e-2)" "unprognostic (8.64e-3)" "unprognostic (2.81e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (5.87e-3)" "unprognostic (5.58e-2)" 1.9 0.1 6.0 12.6 5.6 2.8 2.0 5.7 9.2 61.1 4.5 155.3 62.5 5.1 3.9 24.4 3.8 18.3 3.4 5.5 6.0 0.4 0.1 5.7 1.2 6.1 6.0 0.8 0.7 0.1 0.0 2.1 6.4 6.9 195.9 1.0 26.3 0.5 1.4 0.9 75.8 5.4 5.8 14.6 64.9 3.1 6.1 0.2 0.3 0.9 2.3 3.1 4.5 5.6 0.2 2.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 3.4 0.2 11.9 0.0 0.0 12.4 0.0 2.9 0.0 0.0 0.0 19.5 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 65.5 0.0 0.0 0.0 0.2 0.2 0.0 107.5 0.4 0.0 0.0 0.4 0.1 0.7 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.9 0.1 0.0 0.0 3.4 0.0 0.2 0.0 0.0 0.0 1.3 0.9 6.0 5.6 5.7 9.2 5.5 6.0 6.1 6.0 6.4 5.8 6.1 5.6 8.6 16.0 7.5 0.7 0.3 0.1 5.7 90.2 12.0 0.1 0.1 0.0 2.0 17.2 143.4 0.0 0.0 0.3 0.0 133.3 0.0 1.4 0.3 85.1 7.6 27.2 33.0 6.7 0.4 18.2 0.1 1.3 65.7 77.6 0.0 0.3 8.6 0.0 0.3 0.0 0.3 801.0 50.8 0.0 0.0 0.9 1.5 1.1 0.0 18.7 0.0 0.0 0.0 1.5 0.3 42.8 76.1 0.0 0.0 2.4 51.6 0.0 117.4 1.2 0.0 0.3 5.3 0.4 0.1 12.8 0.1 0.1 1.8 63.3 123.1 24.5 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 83.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 140.5;Club cells: 72.6;Prostatic glandular cells: 85.1;Theca cells: 64.4;Urothelial cells: 54.0" "Cancer enriched" "Detected in all" 6 "prostate cancer: 94.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.1;CAPAN-2: 135.2;U-138 MG: 169.2" "Low region specificity" "Detected in many" HPA030985 Uncertain NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA030985: AB_2673686" "unprognostic (2.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.21e-3)" "unprognostic (9.20e-3)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" "unprognostic (6.74e-3)" "unprognostic (6.36e-2)" "unprognostic (6.45e-3)" "unprognostic (8.31e-3)" "unprognostic (3.79e-1)" "unprognostic (2.60e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-1)" "unprognostic (6.09e-2)" "unprognostic (1.38e-1)" 32.9 2.2 1.0 32.9 1.4 0.0 18.5 0.8 2.3 9.6 1.4 18.1 5.2 4.2 0.8 12.6 10.7 16.4 7.2 1.3 1.0 6.6 27.6 14.2 0.3 1.3 0.8 6.0 6.0 0.3 3.7 0.7 1.0 83.8 13.7 0.7 15.1 2.1 1.3 4.6 7.8 26.9 0.8 2.5 13.9 4.2 1.0 0.9 5.0 2.5 4.6 34.5 5.8 1.1 26.9 52.5 3.3 9.8 105.1 89.5 0.9 17.8 20.5 2.4 2.7 38.8 135.2 0.3 0.9 28.9 43.5 5.3 22.0 22.6 5.1 0.0 7.6 0.1 0.5 13.0 4.3 0.0 0.1 59.7 3.7 68.0 37.4 16.6 92.6 7.3 1.2 74.0 29.6 0.4 0.0 0.9 15.7 1.3 23.2 0.1 0.0 0.3 20.8 5.5 0.0 1.2 6.4 0.2 12.1 1.9 29.4 0.4 50.8 169.2 8.0 83.9 22.8 14.0 0.5 0.1 83.4 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.8 2.3 1.3 1.0 1.3 0.8 1.0 0.8 1.0 1.1 1.8 0.0 0.5 2.3 0.3 4.2 41.9 140.5 7.4 0.1 12.8 11.4 0.8 5.7 72.6 1.8 0.0 0.0 0.6 7.0 0.0 3.4 0.4 1.3 4.9 4.5 7.2 0.0 5.3 38.6 0.1 25.2 10.7 4.6 0.0 10.5 1.8 33.1 0.5 0.0 1.7 4.3 24.4 0.8 5.4 1.1 0.9 1.3 7.2 0.0 0.0 10.5 0.0 1.5 1.3 44.4 20.5 1.5 1.3 85.1 2.5 14.7 13.1 0.3 6.6 6.0 26.9 17.1 36.9 12.2 2.3 0.3 0.4 64.4 16.6 54.0 STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 127.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Inhibitory neurons: 53.0;Prostatic glandular cells: 102.9" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.5;CAPAN-2: 48.1;U-138 MG: 27.4" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" 20.0 3.7 7.3 11.9 10.4 0.0 13.0 8.3 18.5 9.5 6.9 15.1 6.1 7.1 2.7 6.9 14.3 10.1 15.1 11.2 6.9 6.8 4.0 20.5 0.4 3.1 5.0 17.2 8.1 10.1 19.4 0.2 3.8 127.7 7.6 3.9 11.9 6.9 1.4 4.7 9.1 10.8 5.4 2.7 11.0 1.1 6.4 3.3 7.9 1.6 1.7 15.8 9.0 5.7 3.2 22.5 0.5 6.3 11.5 11.1 0.3 2.8 5.8 0.4 0.8 4.2 48.1 0.0 0.3 7.5 8.8 1.8 4.9 3.5 0.8 0.0 4.7 0.0 0.1 1.1 1.0 0.0 0.1 8.1 0.8 11.5 2.3 9.4 6.1 0.0 0.0 0.4 6.6 0.0 0.0 0.7 9.1 0.0 2.5 0.0 0.0 0.2 10.3 6.6 0.7 2.1 3.5 0.0 0.1 1.0 16.8 0.0 5.1 27.4 6.0 3.8 2.4 0.1 0.0 0.0 11.7 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 10.4 8.3 18.5 11.2 6.9 3.1 5.0 3.8 5.4 6.4 5.7 0.6 0.0 1.1 18.6 0.2 4.8 21.6 20.6 9.1 7.5 16.1 10.3 18.0 18.6 19.4 12.9 2.1 0.0 0.1 15.9 0.0 1.1 0.5 2.8 3.7 2.2 15.7 2.7 68.0 7.4 0.0 27.6 10.7 2.9 0.0 30.4 3.6 5.8 0.0 1.7 53.0 9.8 10.2 0.0 6.2 0.8 15.5 0.7 0.0 2.8 0.0 23.1 0.0 27.6 2.6 11.4 24.0 15.4 0.0 102.9 13.1 10.8 16.0 1.3 0.0 14.7 5.8 3.1 6.2 4.1 5.4 0.0 0.5 9.8 13.8 25.3 STON2 "STN2, STNB2" ENSG00000140022 "Stonin 2" Q8WXE9 14 81260656-81436465 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 79.8" "Cell type enriched" "Detected in many" 4 "Astrocytes: 253.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.2" "Lineage enriched" "Detected in single" 4 "monocytes: 1.2" "Cell line enhanced" "Detected in many" "HEL: 113.4;HMC-1: 60.9;Karpas-707: 58.3;RT4: 46.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003086 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Cytosol" "HPA003086: AB_2302748" "unprognostic (5.28e-2)" "unprognostic (9.83e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.50e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (3.30e-1)" "unprognostic (9.88e-2)" "unprognostic (9.19e-2)" "unprognostic (5.82e-3)" "unprognostic (1.37e-1)" "unprognostic (6.15e-2)" "unprognostic (1.44e-1)" 3.4 0.8 65.6 1.2 64.8 5.5 9.6 31.2 44.7 4.6 14.1 4.4 4.0 1.2 5.1 14.3 10.7 5.9 3.0 60.1 79.8 14.3 3.0 5.0 1.0 36.5 68.3 2.8 0.9 0.3 10.0 2.5 39.5 2.1 5.0 10.2 5.6 2.7 13.2 8.0 4.3 1.7 27.0 16.3 5.7 3.3 60.9 2.5 10.8 17.4 2.9 6.3 9.5 53.7 4.7 3.1 12.1 0.2 0.0 0.1 13.4 0.0 0.1 0.0 0.3 10.0 4.2 0.0 5.5 0.0 3.4 30.6 16.5 39.8 0.0 0.8 5.5 113.4 19.9 4.2 0.0 0.0 60.9 1.7 33.5 0.0 11.0 0.0 0.0 6.1 40.2 58.3 1.2 6.8 5.4 0.0 11.9 11.5 2.4 0.1 17.6 3.4 8.4 46.0 28.1 1.7 13.7 0.6 0.0 9.9 1.7 0.3 0.3 2.4 8.8 9.7 2.6 6.0 11.9 0.1 8.4 0.4 2.6 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.1 65.6 64.8 31.2 44.7 60.1 79.8 36.5 68.3 39.5 27.0 60.9 53.7 6.3 3.2 0.5 253.4 0.1 13.6 13.2 20.5 30.7 0.6 11.8 8.1 1.1 2.8 6.8 18.4 12.5 1.4 0.1 4.8 7.9 0.6 0.4 56.0 1.2 5.0 0.0 12.2 0.9 0.5 0.4 8.3 7.1 16.1 0.0 12.5 4.2 0.9 3.4 3.3 4.4 3.2 14.2 18.0 6.1 1.6 10.2 13.5 1.8 23.4 2.3 23.9 0.0 12.1 15.2 3.2 2.7 8.6 1.0 6.8 4.6 20.6 5.8 6.1 0.0 36.1 3.2 1.0 5.9 24.3 8.8 15.5 0.9 6.3 2.7 33.2 STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 85.0;granulocytes: 90.3;Langerhans cells: 271.6;Macrophages: 158.0;monocytes: 85.5;Suprabasal keratinocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cell line enhanced" "Detected in some" "HDLM-2: 17.2;Karpas-707: 10.1;RH-30: 6.9;TIME: 8.3;U-266/70: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" 25.1 4.4 0.6 5.8 0.6 56.5 14.5 0.6 1.1 1.9 0.7 2.8 1.0 1.4 0.3 5.1 2.6 2.1 7.3 0.7 0.8 3.6 3.1 21.3 5.5 1.0 0.7 0.9 1.1 0.6 2.1 2.4 0.9 1.3 0.9 0.2 2.1 0.3 2.5 8.2 3.3 1.9 0.8 14.1 2.0 1.1 0.9 1.8 7.5 0.9 3.5 4.0 3.2 1.1 0.4 0.1 0.1 3.9 0.2 0.3 0.6 0.4 0.3 0.4 0.7 0.1 0.4 0.1 0.4 0.6 0.7 0.6 0.0 0.1 0.2 17.2 0.6 3.0 0.6 0.1 1.0 0.9 0.5 0.0 0.0 0.2 0.1 0.2 4.3 0.8 0.1 10.1 0.5 0.2 0.4 0.9 0.0 0.0 0.3 0.1 6.9 0.6 0.0 1.9 0.2 0.1 1.2 0.1 1.7 0.3 0.1 3.8 8.3 0.2 1.0 0.4 0.3 11.6 4.6 0.1 0.2 2.1 0.4 22.6 68.4 43.5 6.0 81.1 3.8 1.4 2.7 5.1 25.4 2.4 1.0 3.0 81.7 3.2 87.0 2.7 8.3 43.9 0.6 0.6 0.6 1.1 0.7 0.8 1.0 0.7 0.9 0.8 0.9 1.1 41.9 54.5 10.7 0.0 16.6 85.0 11.3 6.3 3.4 0.0 11.1 4.6 4.5 4.3 6.6 1.8 0.0 0.9 38.1 0.1 0.0 6.4 0.4 3.7 0.7 23.7 3.5 6.1 0.1 2.6 5.7 11.2 0.5 5.0 90.3 0.2 8.2 1.4 30.1 0.0 0.1 0.4 2.0 73.7 271.6 1.2 0.6 158.0 44.4 2.8 85.5 0.0 21.6 0.0 0.1 6.1 3.3 0.0 63.1 14.4 0.0 0.1 10.7 0.1 0.0 46.6 9.7 3.0 3.8 11.2 154.6 28.0 36.6 3.2 0.6 33.3 STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 131.0;Cone photoreceptor cells: 156.4;Excitatory neurons: 243.2;Inhibitory neurons: 157.5;Rod photoreceptor cells: 155.6" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 144.1;SK-MEL-30: 131.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" 27.5 28.8 22.8 7.8 33.2 1.1 21.0 38.6 174.5 21.8 0.0 15.9 5.5 24.1 7.1 10.4 32.3 11.4 24.0 48.3 12.2 14.1 3.1 32.1 6.0 48.7 0.0 25.2 24.8 15.0 66.4 14.1 33.1 10.5 8.4 214.2 15.6 10.4 9.0 11.4 9.3 21.0 0.0 10.4 13.3 9.1 6.8 5.8 20.1 9.2 7.0 15.4 16.4 27.2 13.2 27.1 25.5 28.8 56.6 48.3 23.2 45.0 22.9 26.6 23.3 1.5 15.4 13.1 24.2 29.7 74.2 4.7 22.6 28.1 32.7 29.8 15.4 17.1 69.7 4.9 28.5 1.8 14.6 36.6 15.4 70.0 33.7 42.6 32.2 43.4 17.8 19.6 45.5 24.5 12.5 5.2 21.5 21.4 35.9 7.5 12.1 31.3 22.0 0.6 144.1 69.9 72.9 37.2 131.9 22.5 5.8 5.6 47.5 30.0 15.1 59.9 17.4 40.2 73.2 17.4 59.2 18.9 28.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.9 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.2 22.8 33.2 38.6 174.5 48.3 12.2 48.7 0.0 33.1 0.0 6.8 27.2 24.3 25.6 70.7 34.0 1.2 11.6 10.1 8.4 12.5 131.0 10.5 8.0 15.2 1.5 9.2 3.7 156.4 2.7 1.1 0.5 7.9 13.1 2.2 8.3 14.7 28.9 45.6 4.0 243.2 8.4 5.9 18.7 3.1 7.0 5.1 5.0 26.7 1.4 4.4 84.1 157.5 10.2 8.2 2.5 5.6 2.2 20.5 3.0 10.6 45.0 0.6 27.0 0.0 61.3 39.0 5.3 0.0 44.4 1.6 10.8 0.1 8.9 15.9 155.6 13.1 9.5 11.2 40.6 16.9 2.9 7.5 24.5 2.3 17.7 0.9 7.1 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.1;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Excitatory neurons: 20.6;Gastric mucus-secreting cells: 15.3;Paneth cells: 12.6;Proximal enterocytes: 10.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 28.7;HDLM-2: 17.5;HMC-1: 18.3;HUVEC TERT2: 25.5;TIME: 23.8" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.4 0.3 1.2 1.8 3.0 1.1 3.9 0.0 5.2 1.9 0.0 15.9 2.4 0.5 1.2 7.3 2.2 3.5 0.1 3.6 0.0 0.6 0.3 1.3 1.4 0.0 0.0 0.3 0.3 0.0 2.4 0.7 0.0 11.6 17.1 0.9 6.7 0.9 0.1 2.8 11.2 0.6 0.0 0.9 17.5 0.2 0.0 0.2 0.4 0.0 2.5 5.1 3.3 0.3 4.8 0.2 0.0 0.6 0.0 0.0 1.3 7.3 0.7 3.5 3.4 2.6 28.7 0.3 4.7 1.8 4.5 1.4 1.6 8.0 7.4 17.5 0.4 1.0 2.4 0.2 0.0 2.2 18.3 0.4 0.4 5.1 0.3 0.5 25.5 0.2 0.3 0.3 8.1 3.1 0.2 1.3 4.2 11.8 2.0 0.1 2.0 0.3 2.5 14.6 0.9 0.1 4.5 4.9 0.0 6.7 3.5 0.6 23.8 1.0 3.8 0.5 0.8 0.0 1.0 0.2 3.5 0.2 5.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.1 12.5 0.0 0.0 0.0 0.3 1.2 3.0 0.0 5.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.2 0.0 0.0 0.3 0.8 3.1 1.2 0.6 3.3 2.0 0.7 1.5 3.3 0.0 0.0 0.1 1.8 19.6 0.0 0.5 0.2 7.3 0.5 0.4 4.2 0.8 20.6 0.2 0.6 0.2 15.3 4.5 1.3 6.3 0.0 0.0 0.0 0.0 1.6 8.9 2.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 6.2 0.0 0.5 5.9 12.6 0.0 0.9 4.7 10.6 0.0 8.8 0.4 0.0 1.2 0.2 0.2 0.8 3.1 1.0 0.3 1.9 0.0 6.9 5.5 SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.4;stomach 1: 44.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 298.2;Gastric mucus-secreting cells: 61.7;Paneth cells: 153.4;Proximal enterocytes: 234.3;Undifferentiated cells: 76.4" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 10.7;neutrophil: 32.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.9;OE19: 26.3;TIME: 36.2;U-2197: 31.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" 3.0 0.7 2.3 10.7 4.3 5.5 2.1 8.0 6.8 1.5 2.5 69.9 99.4 2.0 2.4 2.0 1.5 1.5 1.9 3.2 1.8 1.9 23.8 2.5 4.2 0.9 0.9 3.0 0.8 0.9 0.1 1.3 2.0 2.5 62.2 3.9 0.8 1.4 1.2 1.3 95.3 5.1 0.3 9.7 44.9 1.2 2.0 3.0 2.7 2.3 7.5 1.6 0.9 5.6 0.7 0.6 0.8 0.8 1.8 1.9 1.2 0.8 0.4 0.3 0.3 0.7 0.7 1.3 0.7 0.8 1.0 1.1 0.1 0.2 0.7 1.5 1.0 1.0 1.2 0.5 2.7 1.3 1.3 12.3 0.2 0.3 0.5 1.1 110.9 1.6 0.6 2.5 1.0 0.7 0.6 1.0 0.8 26.3 0.4 0.6 3.7 0.8 0.2 1.8 1.3 0.8 0.5 0.3 0.5 0.7 1.6 0.6 36.2 1.0 1.7 31.5 0.6 1.9 1.0 0.6 0.4 3.3 1.3 10.7 4.8 1.4 1.0 2.7 0.3 0.1 1.5 0.4 2.7 0.2 4.9 2.5 32.0 2.9 3.4 0.2 0.9 2.6 2.3 4.3 8.0 6.8 3.2 1.8 0.9 0.9 2.0 0.3 2.0 5.6 1.3 19.2 20.8 0.3 0.9 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 8.4 0.0 0.0 0.0 4.9 298.2 0.0 0.3 0.1 1.2 0.1 2.2 33.7 2.7 0.1 4.4 0.2 1.8 61.7 0.2 16.4 0.2 2.9 45.1 0.3 0.0 0.1 42.6 0.0 24.9 1.8 0.0 0.0 9.4 0.0 3.7 15.4 0.0 11.3 0.0 0.1 18.2 153.4 0.0 1.0 0.2 234.3 1.5 12.8 0.0 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.3 6.7 0.1 76.4 0.1 SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.0;skin 1: 186.5;vagina: 145.9" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 62.3;Proximal enterocytes: 75.9;Squamous epithelial cells: 56.0;Suprabasal keratinocytes: 137.4;Urothelial cells: 114.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 74.2;MCF7: 46.8;OE19: 122.9;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Cytosol "HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: " "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" 0.3 0.2 0.5 0.4 0.4 0.1 11.5 0.6 0.8 74.4 0.4 0.8 9.3 0.5 6.8 286.0 1.2 2.7 0.2 0.5 0.5 13.0 0.3 9.4 0.0 0.5 0.7 0.1 0.7 7.9 0.4 1.5 0.5 22.6 0.2 0.0 53.6 3.7 0.4 186.5 18.2 0.1 0.4 0.1 3.5 0.5 0.9 0.4 1.9 0.0 28.3 0.7 145.9 0.5 12.6 15.8 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.9 74.2 0.1 0.1 0.0 0.7 3.9 0.1 0.3 0.0 0.5 0.4 0.0 0.5 0.5 0.0 0.0 7.2 0.2 2.1 0.0 0.0 0.1 0.0 0.8 0.1 0.1 0.0 46.8 0.0 0.5 0.0 122.9 0.0 0.1 0.0 0.1 0.0 3.5 0.2 0.1 0.0 6.2 0.3 0.0 36.7 0.1 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.4 0.3 0.5 0.1 0.0 0.3 0.2 0.6 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.6 0.8 0.5 0.5 0.5 0.7 0.5 0.4 0.9 0.5 0.4 19.2 0.5 1.0 0.0 24.1 30.5 11.6 0.0 0.0 16.8 12.4 0.6 5.7 40.2 9.2 0.0 3.2 0.0 4.4 0.0 12.2 0.0 15.7 1.4 0.9 4.8 0.0 1.0 1.2 3.1 1.2 2.6 17.5 0.0 0.1 0.0 0.3 0.7 0.0 0.9 12.6 24.4 0.0 4.8 0.9 0.3 0.4 12.4 1.0 0.0 1.6 0.0 0.5 0.8 18.5 7.9 0.0 0.0 62.3 75.9 1.3 6.7 0.6 0.0 0.1 2.2 0.2 11.1 56.0 137.4 1.9 0.6 2.0 9.2 114.6 SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.9;Excitatory neurons: 63.4;Horizontal cells: 95.9;Inhibitory neurons: 107.2" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" 1.5 8.9 59.2 2.9 64.7 6.0 1.6 30.2 128.2 6.9 0.0 4.5 1.5 8.4 23.4 1.6 4.8 3.3 1.5 65.1 61.6 1.7 0.5 2.0 2.1 68.2 40.2 3.5 1.4 48.4 22.9 1.4 61.2 4.2 1.8 38.6 1.3 3.7 0.5 0.9 3.0 8.0 14.1 1.6 2.5 1.1 48.9 3.8 4.4 0.5 1.7 3.1 3.9 67.5 0.3 0.0 26.0 0.1 2.6 7.4 2.8 11.2 38.8 32.6 46.7 0.8 1.2 0.3 9.9 16.9 34.3 0.6 0.3 2.4 27.9 0.1 6.2 35.2 2.0 2.0 24.5 0.3 0.5 16.7 0.2 52.3 3.9 36.2 2.9 31.7 0.4 35.8 21.8 0.3 34.8 1.7 66.3 0.0 0.2 12.0 16.4 0.7 0.2 0.9 54.2 43.8 0.1 0.4 25.6 24.6 0.4 21.4 0.2 30.1 29.9 1.2 41.3 0.2 0.5 0.2 53.0 0.3 12.3 0.4 0.1 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.0 0.2 0.1 0.4 0.3 0.3 0.0 0.1 0.6 0.1 59.2 64.7 30.2 128.2 65.1 61.6 68.2 40.2 61.2 14.1 48.9 67.5 0.8 0.0 1.1 12.4 0.3 0.1 1.9 0.7 4.6 111.9 0.7 4.2 0.8 1.5 0.1 0.0 4.2 0.3 0.7 0.3 0.0 0.1 0.6 0.4 4.6 2.4 4.2 2.1 63.4 0.4 0.6 3.3 1.5 1.3 0.0 10.9 7.5 0.1 0.3 95.9 107.2 0.4 0.0 0.0 0.9 0.2 0.0 0.3 0.0 7.5 0.0 22.9 0.0 28.1 15.7 0.2 0.1 5.7 0.5 0.9 0.1 0.1 0.9 16.1 0.0 2.7 4.9 1.3 0.9 0.4 0.4 0.4 2.7 3.0 0.5 0.7 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 106.8;smooth muscle: 54.1;tongue: 73.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 121.0;U-138 MG: 113.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: AB_2672554, HPA063549: " "unprognostic (3.99e-1)" "unprognostic (6.04e-3)" "unprognostic (2.02e-2)" "unprognostic (7.60e-3)" "unprognostic (1.99e-2)" "unprognostic (5.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-4)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.15e-4)" 10.5 8.5 6.4 15.6 6.1 0.7 5.4 6.7 6.6 9.7 6.1 11.6 6.5 10.9 4.9 17.9 7.4 9.5 17.3 5.8 7.9 2.4 2.2 10.5 6.4 8.3 8.7 3.7 2.6 4.7 0.7 2.5 7.9 13.1 8.7 0.4 9.6 14.6 106.8 2.5 7.3 54.1 9.0 6.2 9.0 9.7 7.4 1.1 4.5 73.4 1.7 12.3 2.9 8.2 8.7 7.0 11.2 19.3 19.4 30.5 6.6 41.9 81.5 28.7 19.6 1.2 24.8 23.9 13.0 121.0 43.4 5.8 1.0 0.7 16.2 12.4 0.8 26.1 22.6 18.0 16.4 33.0 12.0 46.6 2.9 31.6 1.1 86.1 9.0 17.2 19.6 26.2 24.3 4.2 32.0 8.9 5.9 11.2 9.6 34.5 36.5 12.7 32.6 14.2 18.1 1.7 57.1 17.6 21.7 22.2 16.0 10.4 14.4 113.0 19.4 69.4 18.8 11.4 21.1 30.2 39.0 10.4 98.3 5.9 7.7 6.1 6.1 9.6 8.1 6.9 6.9 6.4 9.7 5.2 6.2 7.0 0.9 9.1 9.5 12.3 7.9 12.0 6.4 6.1 6.7 6.6 5.8 7.9 8.3 8.7 7.9 9.0 7.4 8.2 10.6 9.6 9.8 15.7 15.1 22.0 14.2 14.5 8.0 50.2 20.6 7.0 1.0 20.0 14.1 9.2 39.6 9.4 20.7 8.3 5.9 11.7 11.2 12.9 25.0 13.1 7.3 16.0 12.2 5.4 9.3 17.1 0.5 16.3 22.2 12.4 22.9 19.1 5.4 74.0 13.2 8.4 8.2 17.7 23.2 14.8 41.7 7.3 33.8 7.5 11.4 20.0 34.0 15.1 11.6 7.9 7.9 64.3 5.7 16.0 10.7 10.1 6.0 53.9 19.7 16.6 12.8 32.8 36.0 7.2 22.3 5.1 15.3 9.4 12.6 9.4 SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 550.1;Bipolar cells: 332.1;Excitatory neurons: 494.6;Inhibitory neurons: 482.6;Microglial cells: 315.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Cell line enhanced" "Detected in many" "U-2 OS: 29.8;U-266/70: 29.1" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" 15.4 17.8 60.2 7.5 68.8 53.6 14.4 152.5 70.2 18.9 182.9 17.2 2.3 19.1 23.7 5.6 26.4 7.9 32.3 92.4 58.1 34.7 14.6 31.3 17.1 55.0 58.8 44.5 20.6 23.6 56.8 4.4 55.6 17.0 6.2 66.3 5.0 12.6 28.0 19.6 11.4 13.1 38.3 32.9 21.6 17.6 55.4 23.9 44.7 16.5 13.4 16.3 12.9 51.5 0.2 5.8 3.7 4.4 5.7 12.1 1.5 14.7 6.9 3.4 6.0 1.3 0.2 13.5 0.7 7.5 11.2 0.3 1.6 3.8 3.5 11.6 4.0 5.2 4.1 4.0 12.8 1.1 2.7 7.9 0.8 7.5 14.9 9.2 6.8 6.9 0.0 14.2 9.2 0.7 2.4 0.2 0.9 1.3 2.2 2.9 8.1 3.5 15.7 0.2 2.6 3.9 2.7 0.8 9.8 3.7 0.8 0.5 9.0 16.3 29.8 5.9 7.6 29.1 12.5 23.3 8.8 2.9 4.6 10.2 2.3 56.8 11.8 1.8 7.9 6.9 10.3 13.4 1.8 8.2 9.7 10.9 1.6 9.9 3.9 1.5 13.2 3.5 60.2 68.8 152.5 70.2 92.4 58.1 55.0 58.8 55.6 38.3 55.4 51.5 139.7 166.7 215.2 550.1 29.1 12.7 5.4 3.0 3.4 332.1 4.9 9.7 117.2 7.2 53.1 44.1 200.1 0.9 132.9 0.4 3.9 24.0 11.5 132.0 118.2 127.5 3.0 11.6 494.6 7.7 14.2 79.6 7.7 17.8 15.2 13.1 90.0 21.8 8.0 138.0 482.6 11.5 2.0 10.1 15.0 12.6 33.2 16.0 16.0 315.7 12.8 27.3 210.1 256.4 108.6 4.2 0.1 39.9 79.6 5.1 0.0 17.8 146.7 145.5 26.3 145.8 85.6 3.9 5.7 2.2 9.7 1.2 74.7 62.2 0.4 2.2 SYNE4 "C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4" ENSG00000181392 "Spectrin repeat containing nuclear envelope family member 4" Q8N205 19 36003307-36008813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 32.0;Breast myoepithelial cells: 35.9;Cytotrophoblasts: 32.6;Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 32.5;Hep G2: 29.1;MCF7: 34.2;SK-BR-3: 40.1;T-47d: 31.0" "Region enriched" "Detected in single" 15 "cerebellum: 6.8" "Not detected" "Not detected" HPA060253 Uncertain NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA060253: AB_2684233" "unprognostic (8.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.24e-1)" "unprognostic (5.54e-2)" "unprognostic (2.42e-3)" "unprognostic (3.76e-2)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (3.36e-3)" "unprognostic (6.02e-2)" "prognostic favorable (8.64e-9)" "unprognostic (1.25e-1)" "unprognostic (2.54e-2)" "unprognostic (4.50e-1)" "unprognostic (1.97e-2)" 0.2 0.2 1.2 0.2 1.0 0.2 5.2 6.7 1.5 2.6 2.5 1.9 3.2 0.7 7.7 1.2 3.9 1.6 0.2 0.7 2.9 8.4 12.0 3.1 0.2 3.7 3.0 0.3 5.4 12.1 12.7 1.6 3.6 10.9 1.4 0.2 9.2 4.0 0.3 1.1 1.3 0.2 1.3 0.3 3.4 0.2 2.5 1.7 8.6 0.0 0.3 0.8 1.3 1.2 0.3 0.3 0.2 0.4 0.1 0.2 4.3 0.0 0.0 0.0 0.1 32.5 3.8 0.3 0.4 0.0 0.2 0.0 0.3 0.4 0.0 1.1 0.5 0.1 0.8 29.1 0.5 0.0 0.2 0.2 0.2 1.1 0.0 0.0 0.2 1.6 0.4 0.4 0.0 34.2 0.5 0.1 0.2 0.3 0.2 0.9 0.0 0.4 2.2 1.0 5.0 0.0 0.0 40.1 0.2 0.2 31.0 0.3 0.0 0.3 0.6 0.5 0.2 0.5 0.7 0.6 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 6.7 1.5 0.7 2.9 3.7 3.0 3.6 1.3 2.5 1.2 0.3 6.4 17.5 0.3 0.7 0.5 14.9 19.9 5.2 0.9 32.0 35.9 0.4 24.3 20.2 29.5 4.2 32.6 0.8 5.4 25.4 21.2 0.0 9.1 1.0 0.8 29.8 0.0 0.6 8.6 24.7 0.7 8.2 10.7 1.3 0.5 0.7 12.5 2.6 0.0 0.9 10.6 26.4 0.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.9 11.7 16.9 0.0 0.0 23.9 4.5 24.2 17.3 0.4 0.0 0.3 1.6 0.1 0.4 2.1 0.4 33.9 1.2 0.1 8.8 9.2 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 SYNPO2 MYOPODIN ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 991.6;tongue: 493.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Endometrial stromal cells: 130.0;Excitatory neurons: 149.6;Peritubular cells: 101.5;Sertoli cells: 131.5;Skeletal myocytes: 93.4;Smooth muscle cells: 206.1" "Group enriched" "Detected in all" 5 "prostate cancer: 25.7;stomach cancer: 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 57.8;LHCN-M2: 18.5;SH-SY5Y: 83.2" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Actin filaments" "CAB037231: AB_262098, HPA030665: AB_10696210, HPA049707: AB_2680857, HPA068563: AB_2686006" "unprognostic (1.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.50e-2)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (5.71e-4)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.91e-4)" 57.5 10.8 6.1 47.4 7.9 0.3 35.9 4.1 5.7 55.0 2.2 346.4 34.3 137.1 33.4 197.1 89.5 50.0 66.8 10.7 13.3 8.7 7.0 16.2 10.5 5.4 7.5 39.0 3.8 3.6 7.5 20.8 6.1 180.5 58.0 1.2 16.0 267.4 991.6 17.9 75.5 244.4 9.2 10.2 126.2 6.7 5.8 14.3 16.0 493.5 6.5 226.5 54.0 12.0 0.2 4.2 0.2 0.0 10.5 3.5 0.7 13.4 14.1 0.4 0.5 0.0 0.7 1.5 0.1 57.8 0.9 0.2 0.4 0.3 0.7 5.9 0.1 0.8 1.3 0.0 2.4 0.1 0.2 14.5 0.3 4.0 0.2 3.7 0.2 0.2 0.0 0.7 18.5 0.3 0.7 7.2 1.4 0.0 0.0 0.5 1.5 0.4 0.2 0.3 0.4 83.2 0.4 0.3 0.1 3.3 0.0 7.0 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.6 0.2 0.8 0.1 0.5 0.2 0.0 0.4 0.3 0.4 0.2 0.0 0.4 0.4 0.3 0.2 0.3 0.1 0.0 0.5 0.1 6.1 7.9 4.1 5.7 10.7 13.3 5.4 7.5 6.1 9.2 5.8 12.0 25.5 3.2 1.1 42.7 1.1 13.5 17.9 3.7 46.1 2.5 6.3 30.7 135.4 0.0 0.3 1.8 0.0 1.4 0.5 0.1 0.0 0.1 2.2 6.9 130.0 11.3 0.0 1.7 149.6 1.8 0.5 41.5 0.5 10.6 0.0 16.1 13.9 0.4 1.4 0.0 31.5 0.2 0.0 0.9 11.4 7.0 27.1 3.8 5.4 76.8 12.9 0.0 0.0 6.0 3.0 0.2 0.4 101.5 0.8 24.9 0.1 0.3 2.5 0.5 131.5 93.4 206.1 1.3 0.5 5.3 8.1 0.8 2.6 33.4 0.2 4.0 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 SYT12 SRG1 ENSG00000173227 "Synaptotagmin 12" Q8IV01 11 67006778-67050863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 22.5;liver: 17.6;parathyroid gland: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 8.8;Basal respiratory cells: 10.9;Excitatory neurons: 39.3;Inhibitory neurons: 21.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HeLa: 49.8;MCF7: 38.0;SiHa: 44.3;SK-BR-3: 20.9;T-47d: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011006, HPA074255" Enhanced NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA011006: AB_2286996, HPA074255: " "unprognostic (2.72e-2)" "unprognostic (2.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.12e-3)" "unprognostic (4.47e-3)" "unprognostic (3.88e-2)" "unprognostic (1.20e-1)" "unprognostic (3.73e-2)" "unprognostic (2.04e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (4.13e-4)" "unprognostic (2.75e-1)" "unprognostic (9.86e-4)" "unprognostic (4.21e-2)" "unprognostic (7.38e-2)" "unprognostic (2.42e-2)" "unprognostic (9.85e-2)" 0.6 6.9 9.4 0.2 10.9 0.0 4.6 22.5 19.0 0.2 1.7 0.0 0.7 0.1 5.1 0.4 3.8 0.6 0.7 9.9 7.6 0.3 17.6 0.0 0.1 10.3 9.5 0.1 0.3 63.8 5.6 0.8 10.9 1.6 0.0 0.4 1.6 0.8 0.3 0.8 0.3 0.0 4.8 0.0 0.3 1.4 7.9 0.0 0.4 0.0 0.1 1.2 0.2 10.9 0.0 2.0 0.3 3.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 8.1 1.5 3.4 1.3 0.3 1.5 0.2 4.5 0.0 0.0 0.4 0.0 49.8 0.1 0.0 0.0 0.1 0.5 0.3 0.1 0.0 4.6 0.0 0.0 0.1 0.1 0.0 38.0 0.0 0.1 0.9 0.2 1.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 44.3 20.9 0.1 0.1 19.3 0.2 0.0 0.0 7.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.9 22.5 19.0 9.9 7.6 10.3 9.5 10.9 4.8 7.9 10.9 0.2 0.0 0.0 8.8 0.1 1.3 3.8 10.9 0.0 2.2 6.9 6.6 1.2 1.5 3.1 1.8 0.0 0.4 0.1 0.5 0.0 2.9 0.5 0.8 0.3 0.4 0.0 0.0 39.3 0.0 1.5 1.1 0.0 0.5 0.0 0.3 0.0 5.8 0.1 0.0 21.6 0.0 0.0 0.0 1.2 0.2 0.0 0.1 0.0 4.7 0.0 0.1 0.0 3.0 2.3 0.4 0.0 0.4 0.1 1.2 0.2 0.1 1.6 1.2 0.0 1.2 1.6 0.8 1.2 0.0 1.1 1.9 0.5 0.0 0.4 1.3 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;liver: 86.7;salivary gland: 57.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Enteroendocrine cells: 49.8;Excitatory neurons: 82.1;Hepatocytes: 70.7;Prostatic glandular cells: 36.8;Syncytiotrophoblasts: 66.4" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Region enhanced" "Detected in many" "cerebral cortex: 78.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;hTERT-HME1: 89.5;RT4: 37.8;SCLC-21H: 28.4;SK-BR-3: 40.7;T-47d: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" 3.8 4.3 17.7 1.2 33.8 0.1 9.2 0.0 78.4 3.1 0.0 5.0 2.3 2.6 1.8 3.5 3.4 1.2 19.0 30.7 1.9 24.7 86.7 1.9 0.3 0.0 1.9 1.3 16.7 5.7 51.6 18.4 0.0 50.8 5.3 8.0 57.0 0.9 3.6 4.2 5.2 1.8 0.0 2.1 3.7 4.0 13.9 0.4 8.0 1.8 0.3 1.9 3.3 38.5 13.4 1.9 0.5 0.2 1.0 14.1 10.4 0.2 35.0 0.6 0.5 3.5 6.9 0.0 0.6 0.2 1.3 6.9 0.9 0.2 0.2 0.2 1.7 0.0 1.7 2.1 0.9 0.1 0.1 0.4 7.8 4.2 89.5 0.2 0.2 0.8 0.1 0.2 0.5 21.6 0.1 0.3 2.4 24.8 14.1 0.0 0.7 1.7 0.0 37.8 28.4 5.2 1.9 40.7 0.3 5.6 39.8 0.0 0.0 8.6 3.1 10.1 0.2 0.0 0.0 0.1 0.9 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 33.8 0.0 78.4 30.7 1.9 0.0 1.9 0.0 0.0 13.9 38.5 10.6 0.0 0.5 4.2 0.2 0.3 0.4 5.1 0.0 22.6 23.2 16.3 22.3 1.5 5.0 5.5 0.0 45.2 0.6 1.9 5.9 1.2 8.4 0.3 4.3 4.9 49.8 2.7 82.1 1.6 3.4 3.0 0.0 0.5 0.0 5.9 4.6 70.7 4.0 21.9 17.8 30.2 6.1 1.0 0.0 7.6 3.4 0.1 1.8 7.5 0.0 0.6 0.0 6.0 2.5 1.0 4.6 2.2 0.0 36.8 3.5 0.1 1.3 3.5 0.0 2.8 1.4 0.8 3.9 0.9 0.1 66.4 0.2 0.6 2.4 1.7 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 184.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.7;Kupffer cells: 2.4;Leydig cells: 2.8" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 4.2;U-87 MG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 0.9 0.3 1.3 2.5 1.2 0.4 0.8 1.5 1.7 10.3 0.2 184.0 5.0 25.2 0.2 14.7 20.4 0.5 3.2 1.7 0.1 0.3 0.5 0.7 0.3 0.0 0.2 1.8 0.3 0.0 0.2 0.2 0.1 6.2 9.1 4.1 0.5 1.1 2.8 1.1 31.4 33.1 0.0 0.3 37.9 0.7 0.0 0.1 0.4 0.2 0.1 32.3 8.5 0.4 0.9 0.6 0.2 0.3 1.4 0.1 0.1 0.2 0.1 0.2 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.8 0.1 0.0 1.4 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.2 0.2 0.8 0.9 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.6 1.2 4.2 0.1 0.5 0.1 0.3 1.4 0.2 0.6 0.5 0.5 0.6 0.1 2.3 0.1 0.8 0.2 0.4 0.0 0.1 1.3 0.1 0.3 0.2 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 1.3 1.2 1.5 1.7 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.0 0.5 0.3 0.1 0.6 0.2 0.2 0.0 0.2 1.1 1.4 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.6 0.0 0.2 1.4 0.1 1.2 6.7 0.1 0.3 0.0 2.4 0.4 0.1 2.8 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.4 0.1 1.5 0.2 0.0 1.1 0.7 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.4 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TBC1D1 "KIAA1108, TBC, TBC1" ENSG00000065882 "TBC1 domain family member 1" Q86TI0 4 37891084-38139175 "Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 310.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041816, HPA058158" Approved Approved Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "HPA041816: AB_10796784, HPA058158: " "unprognostic (3.77e-2)" "unprognostic (3.44e-1)" "unprognostic (1.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (1.32e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "prognostic favorable (1.47e-8)" "unprognostic (1.49e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.21e-1)" 32.0 10.9 21.6 38.3 19.8 64.2 23.0 14.6 19.7 50.4 44.7 123.8 30.7 139.8 46.4 22.9 61.1 44.6 56.1 26.8 12.3 83.5 26.2 32.4 53.8 17.8 14.3 24.7 28.3 134.2 16.8 41.3 15.4 22.7 28.3 9.6 20.5 40.2 110.0 12.2 35.3 91.2 14.4 39.8 34.3 48.1 13.0 59.0 56.7 149.9 41.3 51.6 23.8 16.8 23.2 26.1 46.7 50.5 16.4 45.3 40.2 61.9 103.6 57.3 58.0 15.0 73.8 118.6 15.0 41.5 72.1 1.0 35.8 45.0 87.6 9.4 20.2 45.9 17.1 31.6 26.2 85.7 50.0 55.4 8.9 35.3 24.4 47.7 89.4 81.6 57.0 19.8 60.3 17.7 119.5 80.5 26.3 3.6 23.6 104.9 75.8 34.7 47.3 42.4 40.7 36.5 23.0 21.1 25.6 104.9 20.5 65.4 61.4 75.1 84.3 19.0 91.4 48.1 63.7 310.4 32.8 76.9 68.2 2.9 7.6 23.2 3.8 25.2 6.2 7.1 3.7 3.1 7.4 9.0 3.3 4.2 20.5 9.7 28.2 6.2 3.3 3.9 21.6 19.8 14.6 19.7 26.8 12.3 17.8 14.3 15.4 14.4 13.0 16.8 38.3 12.8 6.7 50.9 42.0 7.9 14.0 5.0 4.6 12.4 15.1 9.8 73.9 22.8 8.3 27.6 0.0 20.1 30.7 26.0 76.3 13.8 27.6 19.4 27.6 39.9 44.3 11.6 75.9 40.8 27.6 15.5 7.1 25.8 2.5 24.3 27.8 19.8 31.0 10.1 37.7 11.9 36.7 68.6 21.4 50.2 23.3 52.2 10.6 91.8 51.0 9.8 25.7 45.8 9.2 38.7 17.6 19.9 40.7 37.3 13.1 77.3 14.8 1.1 39.5 17.4 79.5 13.0 19.4 3.4 8.7 29.1 32.0 7.4 11.9 35.9 TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 40.4;intestine: 25.6;lymphoid tissue: 58.6" "Group enriched" "Detected in many" 4 "B-cells: 109.6;dendritic cells: 144.4;NK-cells: 284.2;T-cells: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 19.0;JURKAT: 27.3;MOLT-4: 47.1;NB-4: 64.7;U-937: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA069743: AB_2686186" "prognostic favorable (3.83e-4)" "prognostic favorable (4.20e-4)" "unprognostic (9.23e-2)" "unprognostic (3.84e-2)" "unprognostic (1.28e-3)" "prognostic favorable (1.86e-5)" "unprognostic (6.22e-3)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (3.55e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (7.18e-2)" "unprognostic (3.81e-2)" 2.3 0.7 0.7 25.8 1.2 40.4 1.1 0.4 1.2 1.4 0.8 4.1 5.5 0.9 0.1 2.3 1.9 3.2 0.9 0.6 0.6 2.5 2.6 8.9 56.7 0.9 0.5 0.5 0.8 0.2 0.5 0.8 0.6 1.9 1.5 0.0 3.8 0.7 0.9 1.4 25.6 0.5 0.5 58.6 7.6 0.5 0.7 46.0 7.6 0.6 21.8 3.2 1.7 1.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.7 0.1 1.2 0.0 6.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.1 0.0 0.0 0.3 47.1 64.7 0.0 0.0 0.0 6.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 4.5 0.0 0.0 0.1 0.2 0.0 0.4 0.5 12.2 0.0 24.6 0.0 191.0 46.0 270.4 237.7 120.4 169.7 177.3 201.5 208.3 65.6 184.2 206.7 192.0 237.6 148.0 167.0 55.8 286.6 261.6 0.7 1.2 0.4 1.2 0.6 0.6 0.9 0.5 0.6 0.5 0.7 1.1 2.5 6.4 19.5 0.0 109.6 1.1 0.1 0.1 0.6 1.0 1.4 1.9 1.5 2.8 2.5 0.0 0.0 0.2 144.4 0.2 0.0 0.2 0.2 2.4 0.4 1.9 1.2 12.6 0.2 0.0 0.3 2.0 2.0 1.1 23.4 0.1 5.0 1.4 23.7 0.0 0.1 0.0 0.0 16.0 6.9 0.6 0.0 23.1 3.6 1.0 24.5 0.3 284.2 0.0 0.5 0.0 0.0 0.0 40.2 0.1 0.1 1.1 1.3 0.5 0.0 1.3 1.1 0.1 0.2 0.0 1.0 0.4 147.7 0.1 0.1 0.1 TBL1Y TBL1 ENSG00000092377 "Transducin beta like 1 Y-linked" Q9BQ87 Y 6910686-7101970 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 2.9;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Inhibitory neurons: 2.2;Oligodendrocyte precursor cells: 1.0;Squamous epithelial cells: 5.7;Urothelial cells: 1.1" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.7" "Region enhanced" "Detected in single" "basal ganglia: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-698: 12.3" "HPA050857, HPA060073" Uncertain Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA050857: , HPA060073: AB_2684196" "unprognostic (2.81e-3)" "unprognostic (2.94e-1)" "unprognostic (3.06e-1)" "unprognostic (7.76e-2)" "unprognostic (1.17e-2)" "unprognostic (1.28e-1)" "unprognostic (2.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.24e-2)" 0.3 0.0 0.1 0.0 1.3 0.0 0.3 0.1 0.4 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.4 0.9 0.6 0.1 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.1 2.9 0.1 0.0 0.8 0.3 0.4 0.2 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 1.6 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.6 0.0 0.0 0.0 0.0 1.9 0.0 2.2 1.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.1 0.4 0.1 0.4 0.2 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.2 3.4 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.2 5.7 0.0 0.3 0.0 0.0 0.0 1.1 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TBX6 ENSG00000149922 "T-box transcription factor 6" O95947 16 30085793-30091924 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.4;Urothelial cells: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "OE19: 4.1;RT4: 6.9;U-266/70: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062498 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA062498: AB_2732686" "unprognostic (2.47e-1)" "unprognostic (1.32e-3)" "unprognostic (5.62e-5)" "unprognostic (1.49e-1)" "unprognostic (4.76e-2)" "unprognostic (2.35e-2)" "unprognostic (3.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (2.76e-2)" "unprognostic (2.95e-1)" "unprognostic (4.21e-2)" "unprognostic (5.05e-3)" "unprognostic (4.26e-2)" 1.1 1.9 3.3 0.7 3.9 0.5 1.4 3.1 4.1 3.6 2.4 1.8 1.2 1.1 0.7 13.8 1.7 0.8 1.3 3.1 3.3 3.2 1.9 1.4 0.8 3.7 3.7 1.8 4.3 1.0 1.9 0.3 3.9 3.3 0.3 1.7 2.8 1.2 2.0 3.5 1.7 0.4 3.4 2.4 4.7 1.8 4.0 0.9 2.8 0.5 1.5 4.4 7.3 4.5 0.6 0.7 0.4 0.7 1.0 0.5 0.5 0.2 0.1 0.0 0.1 0.9 2.9 1.2 1.5 0.1 0.1 0.8 0.3 0.5 0.0 0.9 0.5 0.8 1.4 0.7 0.7 0.1 1.7 0.2 0.8 0.1 0.3 0.6 0.4 2.7 0.1 2.9 0.0 2.6 0.5 0.3 0.6 4.1 0.6 2.0 0.0 2.1 0.0 6.9 0.9 1.3 0.1 0.5 0.8 0.3 1.2 1.2 0.3 0.8 0.4 0.4 0.0 6.9 1.7 0.2 0.8 1.2 0.2 1.2 0.6 0.2 0.4 0.6 0.3 0.3 0.2 0.3 0.3 1.2 0.4 0.4 0.8 0.3 0.2 0.2 0.5 0.3 3.3 3.9 3.1 4.1 3.1 3.3 3.7 3.7 3.9 3.4 4.0 4.5 1.0 0.0 0.6 2.6 2.7 1.1 3.4 4.2 4.0 1.9 1.2 1.4 0.5 0.0 3.7 1.8 8.4 1.7 0.5 0.7 0.0 0.8 0.1 0.9 0.8 1.9 0.0 3.2 0.2 1.2 0.8 1.1 3.6 1.0 0.0 1.1 0.4 0.4 0.5 0.0 0.4 1.2 4.1 0.8 1.7 0.2 0.9 1.2 0.0 1.9 0.6 1.9 2.1 0.0 2.7 3.5 1.6 1.2 0.2 3.2 2.6 0.7 3.0 3.4 6.6 2.7 1.4 2.6 3.9 6.2 1.0 2.3 0.8 0.5 1.6 9.4 TCEAL1 "p21, pp21, SIIR, WEX9" ENSG00000172465 "Transcription elongation factor A like 1" Q15170 X 103628704-103630953 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leydig cells: 283.6;Peritubular cells: 387.8;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057345, HPA060384, HPA076762" Approved Enhanced Nucleoplasm No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA057345: , HPA060384: AB_2732648, HPA076762: " "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.60e-3)" "unprognostic (6.09e-2)" "unprognostic (2.03e-2)" "unprognostic (9.85e-3)" "unprognostic (6.54e-2)" "unprognostic (4.80e-2)" "unprognostic (2.62e-1)" "unprognostic (2.56e-1)" "unprognostic (5.56e-2)" "unprognostic (8.76e-2)" 34.9 54.7 33.9 13.8 35.6 9.9 39.4 33.6 47.1 107.9 32.6 61.1 15.2 140.8 40.3 37.8 114.3 34.8 32.2 36.0 37.8 25.1 19.0 30.5 14.1 31.7 31.4 174.8 20.3 31.9 33.9 17.8 35.2 63.3 16.8 14.7 16.1 79.3 55.1 17.3 29.2 95.0 31.4 26.2 40.3 20.1 35.8 12.2 31.9 33.6 9.8 97.9 58.3 33.6 21.8 20.6 11.4 15.8 48.2 33.2 15.2 30.2 30.3 28.9 31.2 9.1 21.1 10.0 30.4 39.3 43.9 21.2 19.2 16.0 21.4 0.0 23.9 13.6 27.2 17.8 21.7 0.1 19.7 40.9 30.4 22.4 12.3 47.7 30.1 11.4 5.1 5.5 58.7 24.1 12.1 0.3 3.8 19.3 32.9 12.4 36.8 0.1 40.4 21.3 15.7 13.2 30.6 14.4 35.4 8.3 13.5 12.7 24.0 20.9 7.7 49.3 15.7 5.4 18.6 0.3 27.4 0.1 21.3 26.8 13.2 0.8 15.3 9.4 22.5 31.9 13.7 12.9 26.4 24.9 18.2 20.8 1.4 22.6 4.0 20.9 13.2 12.8 33.9 35.6 33.6 47.1 36.0 37.8 31.7 31.4 35.2 31.4 35.8 33.6 26.5 16.0 31.2 9.4 10.4 29.7 52.7 38.4 24.5 21.8 47.3 42.8 32.9 28.6 37.2 25.8 2.1 30.0 8.9 6.2 56.7 22.9 2.5 27.5 50.0 32.2 27.6 9.1 22.1 24.6 29.8 37.4 7.7 21.9 26.6 22.7 46.1 19.7 34.7 21.9 20.4 13.2 30.5 21.0 23.1 11.7 283.6 16.5 19.6 6.5 19.7 38.6 19.6 16.6 10.3 11.7 17.5 387.8 5.1 18.4 15.0 52.8 48.0 12.3 151.2 32.6 45.3 6.0 8.5 15.5 21.3 7.3 11.3 32.5 19.4 17.6 TCEAL3 "MGC15737, WEX8" ENSG00000196507 "Transcription elongation factor A like 3" Q969E4 X 103607451-103629690 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 165.3;Peritubular cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA045564, HPA058982" Uncertain Uncertain Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (2.55e-1)" "unprognostic (2.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (4.05e-4)" "unprognostic (2.26e-1)" "prognostic favorable (8.33e-4)" "unprognostic (6.35e-3)" "unprognostic (2.30e-1)" "unprognostic (2.22e-3)" "unprognostic (7.19e-3)" "unprognostic (1.79e-1)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" 43.0 61.9 109.1 15.2 111.0 14.9 42.9 108.8 137.0 101.4 111.0 74.0 11.8 171.1 32.4 25.5 120.6 21.2 66.0 104.8 124.0 55.7 9.8 47.5 10.3 117.0 122.9 163.1 34.0 47.7 108.6 17.8 118.0 97.6 9.5 45.9 34.7 70.0 21.5 33.6 32.2 43.1 112.1 43.7 57.5 34.3 116.7 7.0 50.7 10.7 8.0 126.7 68.3 117.5 81.5 8.6 21.5 17.6 72.6 36.8 0.7 118.4 56.4 53.1 70.0 0.0 7.8 0.0 14.3 87.1 94.5 31.3 15.5 46.6 38.9 0.1 3.9 6.0 35.4 0.2 69.8 0.0 25.6 47.9 14.3 37.6 53.9 75.3 36.0 27.6 0.0 23.1 73.6 68.4 3.9 0.6 9.2 0.0 21.9 28.5 13.5 0.3 25.6 16.2 32.7 26.3 5.3 6.9 29.5 10.5 32.4 18.9 47.1 27.6 14.1 56.9 37.5 24.2 12.0 0.1 68.6 0.1 61.9 5.7 8.3 5.1 13.2 4.7 14.3 9.3 11.4 10.4 9.6 10.5 11.1 13.7 1.4 20.0 0.5 12.2 15.9 6.3 109.1 111.0 108.8 137.0 104.8 124.0 117.0 122.9 118.0 112.1 116.7 117.5 39.1 16.0 47.9 6.2 15.9 25.9 91.4 37.8 20.5 57.0 69.8 73.4 50.2 40.0 39.4 75.4 18.8 3.1 19.9 5.1 142.8 41.3 3.3 61.1 165.3 46.2 43.4 6.3 10.0 39.0 3.3 56.3 19.4 40.6 95.8 55.5 58.2 3.8 63.5 18.5 13.8 32.1 36.7 35.1 32.9 17.2 157.2 31.3 16.0 4.7 29.7 137.8 17.5 9.0 12.3 25.3 9.6 256.1 33.0 78.9 0.7 30.6 62.4 35.6 26.3 26.0 62.4 4.4 1.9 10.2 16.9 2.7 21.1 32.9 6.2 45.6 TCEAL4 "FLJ21174, WEX7" ENSG00000133142 "Transcription elongation factor A like 4" Q96EI5 X 103576231-103587729 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 1524.1;Peritubular cells: 1785.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "unprognostic (2.21e-1)" "unprognostic (2.21e-1)" "unprognostic (6.17e-3)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.08e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (4.16e-1)" "unprognostic (2.02e-2)" "unprognostic (7.49e-2)" "unprognostic (3.35e-2)" "unprognostic (5.46e-2)" "unprognostic (7.63e-2)" 167.6 213.2 157.9 44.3 159.0 28.1 156.1 154.5 204.9 517.9 206.4 204.4 32.4 712.6 251.4 113.8 428.0 86.9 179.3 154.9 166.8 144.3 111.4 167.2 30.5 164.6 160.6 855.8 98.1 134.6 180.4 112.1 163.8 318.4 49.5 77.5 88.9 262.6 95.9 146.6 111.8 277.5 157.1 125.7 159.3 118.9 158.0 30.7 134.9 81.5 30.3 423.5 278.9 170.0 153.8 115.2 96.1 85.7 330.5 196.1 96.4 165.0 165.3 101.5 118.2 49.6 112.0 37.9 178.5 181.5 242.6 96.8 107.3 120.2 122.9 0.6 72.4 51.7 179.9 65.0 291.9 0.4 41.2 262.6 182.4 84.5 193.7 253.3 149.2 52.7 0.7 39.9 303.9 376.5 56.5 2.8 87.6 3.6 136.8 55.5 162.8 7.5 155.3 186.4 97.3 95.6 265.4 64.1 224.0 112.0 102.3 25.1 185.3 100.6 39.8 257.3 68.9 11.7 71.7 1.7 138.7 0.7 104.6 12.3 28.5 1.0 12.8 15.3 18.4 36.4 17.5 13.7 37.7 22.8 15.9 16.8 1.1 24.7 11.9 11.8 57.0 13.6 157.9 159.0 154.5 204.9 154.9 166.8 164.6 160.6 163.8 157.1 158.0 170.0 131.6 112.2 159.1 20.9 28.8 130.0 305.9 170.2 117.3 88.5 169.2 191.4 278.7 114.4 130.8 198.6 14.6 222.8 11.7 19.6 385.4 156.6 11.7 117.0 459.5 143.2 104.2 28.6 19.5 95.2 331.5 202.4 46.4 178.9 116.9 167.0 231.0 218.6 148.4 90.9 21.1 44.9 91.6 61.7 80.5 65.2 1524.1 69.9 104.9 11.2 82.3 201.9 4.1 26.2 31.9 68.7 33.7 1785.5 23.3 195.5 7.6 297.2 81.0 60.5 361.6 120.3 192.8 34.8 58.5 91.1 104.3 94.3 29.7 144.7 39.4 135.8 TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 67.3;choroid plexus: 35.5;pituitary gland: 62.2;retina: 23.5;testis: 60.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.4;Granulosa cells: 16.5;Late spermatids: 22.1;Muller glia cells: 75.5;Peritubular cells: 35.7" "Cancer enhanced" "Detected in many" "glioma: 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 9.0;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (1.30e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (9.68e-2)" "unprognostic (8.75e-4)" "unprognostic (1.21e-1)" "unprognostic (8.11e-2)" "prognostic favorable (8.60e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.74e-1)" "unprognostic (6.30e-2)" "unprognostic (6.03e-4)" 0.9 10.5 56.5 0.9 54.9 0.0 2.1 55.4 67.3 6.2 35.5 2.2 0.6 5.6 6.8 0.3 2.4 0.8 2.7 52.9 55.2 0.3 0.1 0.3 0.0 50.8 52.6 5.2 0.9 0.0 62.2 0.0 49.5 3.3 0.7 23.5 1.1 4.1 0.1 0.4 1.2 3.3 44.9 0.0 1.0 60.0 50.3 0.6 2.3 0.7 0.0 1.5 3.8 55.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 54.9 55.4 67.3 52.9 55.2 50.8 52.6 49.5 44.9 50.3 55.4 0.1 0.0 0.0 2.9 0.0 0.1 0.5 0.0 1.8 43.4 0.3 9.5 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.4 0.3 7.5 0.6 0.0 0.0 7.0 0.0 0.4 7.6 0.0 0.2 0.0 16.5 0.0 0.0 0.3 1.7 7.7 0.0 0.0 0.0 1.7 22.1 8.4 0.7 0.0 2.8 0.0 75.5 0.0 7.1 2.8 0.0 0.0 35.7 0.0 0.2 0.0 0.3 0.0 6.8 0.0 6.9 1.4 7.6 1.9 0.1 0.3 0.4 0.1 0.2 0.0 0.2 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCF21 "bHLHa23, POD1" ENSG00000118526 "Transcription factor 21" O43680 6 133889113-133895553 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 100.4;ovary: 88.3;placenta: 137.2" "Group enriched" "Detected in some" 5 "Fibroblasts: 123.8;Leydig cells: 102.2;Peritubular cells: 116.9;Sertoli cells: 118.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.7;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HHSteC: 51.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA013189 Uncertain NA NA "Cluster 19: Lung - Lung function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "HPA013189: AB_10601215" "unprognostic (2.43e-2)" "unprognostic (8.45e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "unprognostic (4.78e-5)" "unprognostic (2.58e-2)" "unprognostic (6.66e-2)" "unprognostic (9.74e-2)" "unprognostic (2.88e-2)" "unprognostic (2.91e-3)" "unprognostic (2.01e-2)" "unprognostic (8.48e-2)" "unprognostic (5.37e-2)" "unprognostic (2.95e-1)" 8.9 10.7 0.1 11.0 0.0 0.0 0.3 0.4 1.7 3.3 2.7 24.6 23.4 9.4 13.1 19.4 3.5 20.2 22.6 1.6 0.0 38.3 5.1 58.5 0.3 0.2 0.0 88.3 10.4 1.3 3.5 137.2 0.1 37.0 21.2 0.0 0.1 42.2 1.1 0.1 26.7 14.3 0.0 100.4 21.0 3.4 0.1 0.1 0.3 0.7 0.0 40.3 8.5 0.1 0.0 1.3 0.0 0.2 0.2 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 51.1 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 1.0 2.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.7 1.6 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 3.2 1.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 5.5 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.6 1.3 0.0 0.0 0.0 0.0 1.9 123.8 0.5 0.0 0.0 0.5 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 102.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.9 0.1 0.3 0.0 0.0 0.0 0.0 118.3 0.3 20.8 0.3 0.4 1.4 0.0 5.7 0.1 14.5 0.0 0.4 TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Astrocytes: 76.4;Leydig cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.3;NTERA-2: 99.0;RH-30: 44.7;T-47d: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" 37.8 5.3 7.5 4.0 9.9 3.7 33.4 7.8 6.4 33.1 13.8 27.6 4.3 25.9 6.7 10.0 20.1 7.2 20.3 6.9 7.7 15.7 12.5 17.8 5.9 10.8 13.0 27.5 4.5 7.0 8.9 5.2 6.9 20.0 4.1 1.7 13.1 14.5 15.0 14.6 12.2 13.0 7.4 11.8 10.7 9.1 10.0 5.8 30.6 7.9 3.5 18.3 24.1 6.7 2.1 1.5 33.5 25.8 12.6 2.6 20.3 2.5 8.5 5.8 5.3 5.2 2.0 0.7 4.0 5.6 6.4 4.7 25.9 43.3 4.0 1.8 4.1 0.7 2.1 2.3 1.2 0.3 4.9 2.1 7.7 0.6 1.4 2.6 11.2 1.3 0.5 1.3 6.8 1.6 0.2 1.6 99.0 1.3 0.9 0.6 44.7 0.5 2.7 3.7 1.0 10.4 4.0 17.1 1.3 25.9 44.3 0.9 12.1 6.5 9.2 0.4 3.3 1.1 0.3 0.4 0.2 1.0 5.2 5.1 0.5 1.1 0.5 0.4 0.7 1.1 0.6 0.7 0.2 1.5 0.7 0.9 1.3 0.9 0.5 0.9 0.6 0.1 7.5 9.9 7.8 6.4 6.9 7.7 10.8 13.0 6.9 7.4 10.0 6.7 49.2 6.4 37.3 76.4 1.0 6.0 14.4 12.9 15.9 0.2 20.0 33.1 9.1 5.7 10.5 16.5 0.0 6.3 0.8 0.3 0.0 3.7 28.2 9.4 17.5 31.4 0.0 0.0 1.1 5.6 4.0 28.9 0.5 16.0 5.1 39.4 45.7 6.7 1.7 0.0 2.2 2.9 8.2 9.1 8.3 5.4 65.3 2.2 3.6 22.5 1.0 4.9 0.0 32.2 1.5 1.1 1.6 28.6 1.4 10.8 5.0 2.2 7.7 0.2 6.6 24.9 28.9 1.9 9.3 3.4 3.4 1.4 1.2 2.9 2.1 2.4 TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "salivary gland: 776.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 52.0;Cholangiocytes: 62.9;Club cells: 94.9;Exocrine glandular cells: 372.3;Glandular and luminal cells: 84.7;Urothelial cells: 61.0" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 124.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2374.2" "Lineage enriched" "Detected in many" 1592 "granulocytes: 2374.2" "Cell line enriched" "Detected in some" 21 "OE19: 159.0" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 4000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "prognostic favorable (1.90e-4)" "unprognostic (1.17e-1)" "unprognostic (5.89e-2)" "unprognostic (3.61e-3)" "unprognostic (2.49e-2)" "unprognostic (5.28e-3)" "unprognostic (4.52e-3)" "unprognostic (3.11e-3)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (9.07e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.56e-8)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" 0.1 0.2 0.0 0.7 0.0 190.7 5.4 0.0 0.2 31.7 0.0 0.2 9.6 3.1 0.0 23.0 1.4 173.8 0.1 0.0 0.0 0.1 0.4 1.4 0.3 0.0 0.0 0.0 5.3 108.5 0.2 0.5 0.0 1.2 0.8 0.0 776.3 0.0 0.1 0.9 1.0 0.0 0.0 4.5 76.3 0.3 0.0 1.3 0.0 0.0 0.9 15.5 10.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 2.2 0.0 0.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 159.0 7.5 0.0 0.2 0.0 1.5 0.0 0.0 0.0 7.3 0.0 1.6 0.0 0.0 3.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 2374.2 0.0 0.3 0.0 0.1 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.4 15.9 0.1 1.4 0.1 0.3 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 19.2 52.0 0.0 0.0 21.9 4.2 0.2 62.9 94.9 23.9 0.0 0.0 0.5 0.3 0.0 23.7 0.4 2.2 8.0 0.4 0.0 0.0 0.1 372.3 0.0 0.1 3.6 84.7 0.0 0.0 0.0 0.3 0.2 0.0 0.1 1.2 12.2 0.6 0.3 0.0 0.3 0.9 0.0 0.0 0.7 0.0 0.0 0.5 0.0 46.5 0.0 0.0 0.1 5.0 0.0 0.3 11.7 0.0 0.0 0.0 2.5 0.0 0.0 6.0 0.1 0.0 0.5 0.0 0.2 61.0 TDRD5 "FLJ34823, TUDOR3" ENSG00000162782 "Tudor domain containing 5" Q8NAT2 1 179591613-179691272 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.5;testis: 21.9" "Group enriched" "Detected in some" 4 "Early spermatids: 36.1;Late spermatids: 12.1;Spermatocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 3.7;SK-BR-3: 5.8;T-47d: 10.3;U-266/70: 14.3;U-266/84: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA029418 Enhanced NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA029418: AB_10603035" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.08e-1)" "unprognostic (2.15e-4)" "unprognostic (3.96e-1)" "unprognostic (4.39e-3)" "unprognostic (4.41e-4)" "unprognostic (3.18e-1)" "unprognostic (4.30e-1)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (6.89e-2)" "unprognostic (2.31e-1)" 0.2 0.3 0.8 0.1 1.4 0.3 3.6 0.0 0.8 0.1 0.0 0.6 0.5 0.0 6.5 0.5 0.9 0.2 0.0 0.7 0.4 1.8 0.0 0.1 0.0 0.9 0.9 0.0 0.2 0.3 2.3 0.2 1.0 0.6 0.7 0.3 0.8 0.3 0.0 0.3 0.4 0.0 0.6 0.0 0.3 21.9 1.1 0.1 0.8 0.0 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.8 0.0 0.7 10.3 0.2 0.0 0.0 1.5 0.0 0.0 14.3 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.0 0.8 0.7 0.4 0.9 0.9 1.0 0.6 1.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 3.5 1.8 0.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 36.1 1.0 0.0 0.1 0.0 0.0 5.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.0 0.0 12.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.1 TDRKH TDRD2 ENSG00000182134 "Tudor and KH domain containing" Q9Y2W6 1 151770107-151791416 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 30.1;testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Late spermatids: 60.4;Spermatocytes: 43.2;Spermatogonia: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016419, HPA019625" Approved Approved Centrosome,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Centrosome "HPA016419: AB_1857870, HPA019625: AB_1857871" "unprognostic (2.27e-3)" "unprognostic (2.89e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (2.63e-1)" "unprognostic (2.91e-1)" "unprognostic (2.06e-1)" "unprognostic (3.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-2)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-3)" "unprognostic (1.14e-1)" 2.5 3.1 5.1 4.4 5.1 1.4 4.5 7.9 5.8 2.1 2.3 3.2 2.2 1.6 6.0 1.8 2.0 1.9 3.5 5.5 6.0 4.0 3.6 4.4 5.9 7.4 5.8 0.9 3.0 30.1 4.6 3.6 8.2 6.0 4.0 9.6 7.0 5.7 4.2 2.2 2.2 2.8 4.7 6.3 2.9 22.2 6.0 10.0 7.3 4.9 5.4 2.6 1.7 5.4 10.8 9.4 8.1 18.8 0.5 0.8 7.7 1.8 1.0 5.6 3.7 6.1 15.1 12.6 16.3 0.7 13.1 6.4 11.9 12.5 8.5 32.5 8.3 12.6 2.6 4.2 3.4 2.4 2.0 1.0 4.8 11.8 5.0 1.6 5.9 24.3 9.8 11.0 1.8 29.3 20.3 3.9 6.2 16.0 16.0 2.5 5.0 26.2 9.6 5.3 11.7 19.2 13.2 10.5 12.4 14.5 22.9 9.4 2.4 2.6 4.6 8.2 10.2 22.2 29.4 14.1 12.0 10.1 3.6 5.2 0.9 2.0 8.2 4.3 12.5 3.9 7.6 8.3 2.0 3.6 5.6 6.9 0.6 7.7 8.0 5.3 9.9 4.1 5.1 5.1 7.9 5.8 5.5 6.0 7.4 5.8 8.2 4.7 6.0 5.4 1.0 3.2 8.3 2.3 2.5 0.3 2.1 1.5 0.6 3.4 4.4 1.1 4.8 0.0 2.2 7.3 4.2 2.7 2.4 0.7 1.9 3.1 23.9 1.5 0.2 1.7 0.0 2.1 6.6 2.5 2.9 0.5 2.6 1.2 4.5 4.6 1.4 1.6 5.4 6.7 5.9 0.9 2.0 2.6 1.3 60.4 0.3 2.3 1.8 2.8 2.2 1.8 0.0 6.0 8.3 1.9 0.3 2.2 1.9 1.6 0.1 1.4 1.4 3.5 13.1 1.9 1.0 43.2 27.4 0.4 0.1 2.5 2.9 0.6 0.9 1.8 TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 230.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA057339: AB_2683413, HPA062471: AB_2684773" "unprognostic (1.00e-1)" "unprognostic (2.53e-2)" "unprognostic (8.84e-2)" "unprognostic (9.93e-3)" "unprognostic (2.05e-2)" "unprognostic (4.50e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "unprognostic (4.40e-3)" "unprognostic (8.39e-2)" "unprognostic (4.76e-2)" "unprognostic (1.41e-2)" "unprognostic (7.08e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "unprognostic (2.18e-2)" 29.5 12.1 11.1 8.2 11.6 0.0 17.8 8.6 8.5 23.4 30.6 36.1 7.7 26.4 7.1 29.8 19.2 18.5 31.3 14.5 14.8 17.2 13.6 15.9 4.2 15.1 12.3 21.9 15.2 27.1 14.4 33.3 10.5 18.8 13.0 10.5 10.2 20.1 67.5 13.2 11.9 27.2 13.3 7.3 16.4 8.6 15.6 4.2 17.8 72.6 5.6 33.9 14.7 12.9 62.8 52.1 43.9 58.7 59.9 62.1 65.4 89.2 76.2 71.6 69.7 53.8 54.5 0.4 23.0 120.9 32.3 37.0 53.7 35.9 115.5 0.2 17.6 0.0 107.3 18.1 55.8 0.0 4.7 51.8 18.3 50.4 68.2 58.6 15.2 3.9 26.0 0.2 111.2 13.1 0.1 0.6 17.2 14.5 23.5 0.3 64.8 33.2 48.2 37.2 26.9 31.2 90.9 43.1 59.0 63.8 20.0 4.4 32.0 107.8 76.2 84.9 59.5 8.6 17.3 12.0 41.6 0.2 69.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 11.6 8.6 8.5 14.5 14.8 15.1 12.3 10.5 13.3 15.6 12.9 37.9 89.8 21.7 230.8 0.4 99.3 32.2 19.3 39.9 12.9 16.4 20.2 75.0 31.5 33.1 49.7 12.5 24.1 0.2 11.0 1.9 16.6 6.5 80.8 97.4 33.3 46.7 0.0 101.8 12.8 52.4 46.5 18.8 142.9 0.0 57.7 25.7 39.8 3.7 1.7 108.4 13.5 10.2 1.9 16.0 7.2 23.6 1.9 24.9 91.8 0.0 31.2 0.0 121.2 69.7 34.8 8.1 24.0 1.4 69.4 6.7 29.8 53.8 17.5 6.6 73.5 46.7 3.0 22.3 29.9 54.8 12.3 2.0 45.5 10.4 54.6 TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 127.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 50.3;Exocrine glandular cells: 38.3;Hepatic stellate cells: 32.2;Proximal enterocytes: 37.9;Syncytiotrophoblasts: 34.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 364.1" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" 17.4 5.2 4.2 7.1 3.6 0.4 12.0 5.6 5.5 10.4 4.0 8.1 4.8 9.7 1.0 7.8 8.3 4.5 20.0 3.5 3.9 33.7 4.6 26.0 1.6 5.3 4.8 4.5 51.1 1.6 3.4 10.9 6.1 8.5 4.1 0.5 8.0 5.0 127.3 16.4 8.4 8.9 4.0 9.0 8.1 3.7 6.4 1.6 23.6 46.7 2.4 11.3 7.1 3.6 37.6 51.5 13.0 36.2 4.0 8.7 137.8 29.5 15.6 49.7 27.8 99.6 39.0 0.3 22.2 22.5 34.0 52.5 51.2 364.1 46.1 0.2 41.2 59.1 43.7 87.7 18.8 12.8 10.7 12.2 14.8 43.3 66.7 20.8 42.9 23.4 38.4 0.5 17.5 53.2 0.7 0.3 99.5 48.0 30.0 27.4 73.7 28.9 23.6 15.3 7.4 13.2 36.4 89.9 27.1 93.8 61.2 21.8 49.4 28.7 100.1 20.2 15.7 0.1 0.2 0.4 23.3 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.6 5.6 5.5 3.5 3.9 5.3 4.8 6.1 4.0 6.4 3.6 17.1 12.8 4.7 0.0 0.1 12.2 12.6 6.1 9.1 0.1 6.6 3.7 2.4 5.7 2.3 7.3 0.0 50.3 0.4 3.7 5.9 17.7 0.3 3.0 5.1 25.9 0.0 0.0 1.6 38.3 18.3 6.6 4.1 5.0 5.7 3.4 32.2 0.4 5.2 0.0 0.5 3.7 2.0 0.8 1.5 2.3 0.0 0.5 8.8 3.7 0.0 0.0 0.0 0.0 0.4 21.1 0.9 0.4 1.2 28.9 37.9 21.1 1.5 0.1 0.0 9.3 12.2 0.5 6.4 5.4 7.7 34.6 0.5 0.4 7.1 4.9 TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 84.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Rod photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA021061: AB_1847687" "unprognostic (8.10e-3)" "unprognostic (7.89e-2)" "unprognostic (9.05e-3)" "unprognostic (5.00e-3)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "prognostic favorable (8.12e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (9.46e-2)" "unprognostic (6.12e-2)" 8.4 7.0 11.7 10.4 12.3 6.1 8.0 6.5 12.5 6.4 4.7 8.5 9.2 6.8 3.0 9.8 6.9 5.7 9.9 12.7 12.9 7.7 9.2 13.3 11.8 11.8 11.2 5.7 84.9 3.1 16.7 8.6 12.7 11.6 5.0 10.2 18.9 3.8 9.1 5.9 10.8 4.7 8.5 18.6 18.3 4.6 11.5 9.5 9.6 5.0 6.7 6.8 6.6 8.2 4.4 6.1 8.4 18.3 7.2 4.3 6.2 9.1 5.0 7.1 8.7 5.8 5.4 3.6 14.4 10.6 8.8 2.8 5.7 4.2 3.0 8.8 8.0 5.3 9.4 5.3 8.5 6.5 9.9 7.5 3.4 6.9 5.3 6.6 25.2 15.1 3.6 15.0 5.4 7.2 9.4 6.8 3.3 8.6 5.9 7.8 8.5 17.7 5.4 4.8 15.0 16.9 5.4 14.9 8.5 6.1 4.8 9.2 26.0 6.7 11.5 17.4 7.6 17.6 9.8 1.9 14.0 5.6 12.5 2.5 2.9 0.9 2.2 3.2 1.3 1.8 2.9 1.7 1.8 1.6 4.8 4.2 3.5 1.0 4.9 2.4 3.0 2.3 11.7 12.3 6.5 12.5 12.7 12.9 11.8 11.2 12.7 8.5 11.5 8.2 32.2 9.6 18.4 18.3 12.3 2.3 2.2 3.7 1.8 37.1 7.0 5.8 11.2 7.2 7.0 5.5 106.3 6.0 10.9 16.0 1.9 6.4 2.1 6.9 5.5 22.9 29.3 2.1 21.1 13.4 9.8 7.2 35.7 8.1 8.2 11.0 21.0 8.5 13.7 32.0 17.8 22.9 10.2 20.5 4.0 2.2 7.2 14.2 1.8 16.9 19.5 11.4 14.4 10.1 10.1 11.9 10.3 3.4 17.4 4.1 10.8 3.6 7.7 66.7 0.0 7.5 7.4 5.5 4.5 7.1 1.8 3.4 16.0 9.0 10.0 2.9 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 635.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;BEWO: 63.3;HDLM-2: 90.0;T-47d: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" 5.0 5.1 12.0 1.6 18.4 0.0 2.0 0.0 12.3 1.5 0.0 4.3 0.8 2.9 0.6 0.8 1.0 2.4 1.4 21.8 8.1 0.9 0.3 0.8 0.8 2.8 7.3 3.8 1.2 5.1 4.5 13.1 0.0 3.7 0.8 3.9 0.6 3.6 2.1 0.4 0.9 2.3 0.8 2.2 0.7 2.1 7.4 2.8 6.1 4.3 1.2 1.6 1.4 2.0 0.3 2.6 66.3 0.4 13.2 23.5 63.3 7.8 2.7 6.9 6.1 33.9 17.6 0.0 0.9 52.6 28.6 3.3 16.0 3.4 6.8 90.0 26.7 0.0 0.0 0.0 1.3 0.0 0.0 31.2 1.2 21.5 15.0 15.4 9.6 0.0 0.0 0.4 10.6 2.3 0.1 0.1 21.4 0.0 2.8 0.0 17.1 0.2 0.1 0.1 27.2 25.2 4.0 0.5 0.1 35.8 86.0 3.4 21.2 53.7 38.2 0.2 39.6 0.0 0.0 0.0 28.2 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 18.4 0.0 12.3 21.8 8.1 2.8 7.3 0.0 0.8 7.4 2.0 0.1 0.0 0.0 23.8 0.0 0.4 0.2 0.7 1.8 50.8 1.6 2.2 3.9 0.0 0.1 3.7 4.2 112.7 0.0 0.0 1.9 0.1 12.4 0.1 4.5 0.7 5.3 0.0 115.6 1.8 54.6 4.1 0.0 0.6 0.0 7.7 1.1 0.7 10.4 5.0 635.6 0.0 0.0 0.0 0.7 3.2 8.4 0.0 1.8 8.4 0.0 10.6 0.0 12.1 24.4 0.4 0.0 2.6 0.0 0.4 0.0 0.3 0.0 3.1 0.0 4.8 3.2 3.8 7.2 1.8 0.0 133.4 0.1 4.1 0.1 0.1 TENT5B "FAM46B, MGC16491" ENSG00000158246 "Terminal nucleotidyltransferase 5B" Q96A09 1 27005020-27012850 "Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 111.8;skin 1: 121.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.8;Breast myoepithelial cells: 24.8;Distal tubular cells: 23.5;Endometrial ciliated cells: 11.7;Glandular and luminal cells: 10.8" "Cancer enhanced" "Detected in many" "testis cancer: 87.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 62.0;hTERT-HME1: 31.6;NTERA-2: 32.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.67e-2)" "unprognostic (5.94e-3)" "unprognostic (1.61e-1)" "unprognostic (5.28e-3)" "unprognostic (3.20e-2)" "unprognostic (2.22e-2)" "unprognostic (2.44e-4)" "unprognostic (4.05e-2)" "unprognostic (1.39e-1)" "unprognostic (6.02e-3)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" 8.5 0.9 0.5 2.6 0.5 0.0 15.7 1.5 0.8 30.9 0.5 45.9 1.1 24.8 0.8 111.8 16.4 1.8 26.3 0.4 0.7 5.8 0.4 12.8 0.2 2.2 0.5 3.6 1.9 1.9 2.6 3.2 1.3 12.3 1.7 3.0 27.6 15.5 2.1 121.3 10.6 12.2 0.3 0.6 17.4 6.4 0.5 0.6 5.0 1.7 5.5 37.3 47.3 0.5 3.9 0.6 7.6 2.3 0.9 1.2 1.9 5.5 1.8 21.5 8.5 15.3 5.0 0.0 9.1 3.0 4.8 12.4 1.3 20.1 5.8 0.0 1.2 0.2 2.9 2.6 10.6 0.1 0.3 4.8 62.0 6.6 31.6 0.0 0.3 0.0 0.4 0.0 2.8 3.0 0.0 1.2 32.8 2.8 1.5 0.4 0.0 0.2 21.3 0.0 0.9 0.6 10.6 23.4 14.3 15.9 18.6 0.3 0.5 5.2 18.0 0.6 1.1 0.3 0.8 0.0 1.1 0.1 3.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.5 0.8 0.4 0.7 2.2 0.5 1.3 0.3 0.5 0.5 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 24.8 0.0 0.0 0.0 0.0 0.0 3.2 0.4 0.0 23.5 1.8 0.0 11.7 1.8 0.5 0.0 0.0 0.0 1.9 3.1 0.5 0.0 10.8 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 5.3 0.1 0.0 0.0 0.0 TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 197.1" "Cell type enhanced" "Detected in many" "Early spermatids: 386.6;Glandular and luminal cells: 283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 230.0;hTCEpi: 263.6;SK-BR-3: 267.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 34000 "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: AB_1857899, HPA018123: AB_1857900" "unprognostic (9.81e-2)" "unprognostic (5.53e-3)" "unprognostic (4.79e-2)" "unprognostic (1.31e-1)" "unprognostic (4.01e-1)" "unprognostic (6.08e-3)" "unprognostic (1.84e-3)" "unprognostic (4.81e-3)" "unprognostic (8.81e-3)" "unprognostic (6.19e-3)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.60e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" 29.3 7.2 2.7 54.4 2.7 44.1 32.2 3.4 3.6 29.0 10.0 134.7 41.1 105.9 21.7 58.2 45.2 37.4 14.7 2.3 2.9 19.3 10.1 41.0 49.6 6.4 3.5 7.3 20.8 15.3 5.7 25.6 3.4 55.2 69.0 13.4 34.2 197.1 5.1 23.2 47.5 147.6 3.2 30.0 52.1 39.9 4.3 33.5 66.4 8.9 51.3 87.1 41.1 3.0 115.9 24.0 27.0 0.2 11.7 29.7 62.3 58.9 28.9 10.9 10.6 60.4 126.2 0.0 230.0 41.7 1.3 116.9 14.4 87.3 26.4 57.3 46.0 11.5 53.1 30.5 69.9 53.6 0.2 66.4 263.6 37.7 95.0 74.9 31.1 0.0 11.9 39.5 3.0 24.4 0.2 0.7 17.8 134.0 67.4 0.2 0.4 46.0 110.9 44.0 12.4 113.4 85.5 267.1 68.2 77.6 0.3 21.5 52.3 0.6 1.5 86.2 0.7 92.6 48.9 1.3 7.4 27.2 89.3 274.7 79.2 221.5 150.2 132.1 144.7 104.6 113.4 137.6 86.9 95.5 111.0 127.6 41.6 205.1 170.5 20.7 130.4 162.8 2.7 2.7 3.4 3.6 2.3 2.9 6.4 3.5 3.4 3.2 4.3 3.0 40.8 243.6 47.0 0.0 60.4 200.4 196.2 64.8 60.3 2.2 62.2 57.0 16.1 47.1 81.7 36.8 12.5 23.2 121.3 140.8 21.5 110.7 386.6 176.7 29.9 49.0 50.6 17.7 0.1 112.3 78.1 23.6 84.1 283.9 18.9 54.1 25.7 11.9 15.4 1.7 0.1 100.7 34.6 58.0 119.0 112.5 1.8 78.0 28.4 10.3 77.6 24.7 201.8 0.0 0.3 196.8 112.1 0.4 76.3 102.4 65.3 13.6 68.1 13.9 6.6 9.0 42.3 19.1 10.6 55.9 122.7 29.1 79.2 8.8 79.7 135.9 TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 222.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 14.6;RT4: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 3.8 2.1 7.1 2.8 10.6 10.2 6.6 10.3 8.3 6.4 4.8 5.3 8.6 3.2 3.7 7.1 3.0 2.6 2.4 7.3 8.0 2.5 6.9 3.9 3.9 10.8 10.1 9.8 3.6 3.4 2.4 3.5 10.3 15.5 7.0 2.8 8.4 2.6 8.3 12.7 10.8 2.9 8.5 5.3 4.5 9.6 9.9 4.2 3.4 4.7 5.2 4.7 7.4 15.1 1.9 0.0 0.9 0.1 3.5 1.8 14.6 0.7 4.9 2.1 3.6 4.3 1.7 6.2 0.6 1.8 5.4 2.3 3.9 3.1 1.6 4.4 4.9 4.2 2.0 3.2 1.9 1.4 11.1 1.9 3.2 2.4 3.4 3.2 1.7 8.1 0.8 12.4 1.4 0.7 3.6 2.9 3.8 1.8 1.8 5.2 0.1 1.5 1.9 14.7 0.4 1.6 3.8 7.3 14.1 8.6 11.3 1.8 0.0 0.2 2.1 1.3 1.3 8.0 5.0 1.2 1.1 0.0 1.0 12.8 4.6 13.3 2.7 3.4 1.9 8.0 2.5 1.8 2.4 6.6 4.1 2.3 19.0 1.5 8.0 1.3 1.9 3.4 7.1 10.6 10.3 8.3 7.3 8.0 10.8 10.1 10.3 8.5 9.9 15.1 3.9 0.0 2.8 54.2 10.7 7.8 7.1 2.8 14.2 2.4 11.9 9.4 1.3 4.3 3.4 0.0 14.6 8.3 4.2 13.9 0.0 1.3 23.7 4.6 1.8 3.2 4.2 5.0 10.2 2.7 2.8 3.7 7.7 8.9 7.0 2.4 2.2 6.3 6.8 0.0 6.7 6.9 4.1 5.5 4.4 7.8 2.8 6.0 3.6 15.9 4.6 1.1 4.1 18.6 222.9 1.1 7.3 1.9 9.8 10.6 14.9 1.2 2.0 3.1 6.6 2.6 6.1 22.0 13.6 12.6 8.5 14.8 4.7 1.8 4.9 8.0 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.2 1.6 3.7 5.2 2.4 19.7 3.0 6.3 13.7 2.5 0.0 4.1 5.4 2.0 1.4 7.6 1.9 2.5 1.2 9.3 1.7 1.6 3.9 4.1 3.7 2.0 1.5 1.5 2.6 2.0 1.5 4.6 2.2 2.5 4.3 3.6 4.2 1.1 1.2 16.2 6.0 2.1 0.6 3.8 4.3 1.6 2.7 5.8 2.3 1.3 4.1 3.4 4.0 5.8 9.0 8.0 14.5 8.9 1.2 1.3 26.4 1.8 2.4 3.4 2.7 16.6 8.1 14.9 3.5 2.4 1.6 9.4 13.0 5.2 3.6 6.7 5.2 19.2 7.0 5.6 5.1 20.2 11.3 2.0 13.3 4.2 9.9 4.3 5.3 10.3 13.4 4.8 2.0 14.6 10.0 13.0 8.1 7.7 2.7 15.4 9.1 5.2 3.8 16.5 18.1 15.5 4.0 10.3 4.9 5.7 6.6 16.1 6.7 3.7 15.4 1.8 6.8 4.2 2.0 12.7 2.4 13.9 4.9 0.1 0.4 0.2 0.0 0.4 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.2 3.7 2.4 6.3 13.7 9.3 1.7 2.0 1.5 2.2 0.6 2.7 5.8 4.2 6.4 9.0 31.3 6.4 49.5 3.5 4.2 14.8 16.3 8.0 5.8 2.9 2.8 8.0 1.8 20.9 7.0 7.3 10.5 0.0 3.5 4.7 18.8 11.9 6.6 6.0 24.8 88.5 4.4 30.1 3.4 13.7 29.6 2.5 6.2 3.6 6.1 10.1 10.1 45.7 8.0 8.2 26.9 23.2 0.8 0.6 26.9 10.6 54.4 27.1 1.5 2.1 41.7 86.7 6.2 7.7 3.0 4.8 6.2 10.3 1.5 11.9 8.6 0.0 3.8 7.7 0.5 2.6 24.4 68.2 2.5 5.5 2.3 6.9 7.0 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.4;Basal squamous epithelial cells: 120.1;Breast glandular cells: 66.1;Breast myoepithelial cells: 79.6;Cytotrophoblasts: 91.7;Extravillous trophoblasts: 59.7;Squamous epithelial cells: 81.0;Suprabasal keratinocytes: 149.3;Syncytiotrophoblasts: 105.6" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "BEWO: 190.6;MCF7: 169.2;SK-BR-3: 308.9;T-47d: 86.8;WM-115: 114.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" 1.8 0.3 1.3 0.2 0.6 0.1 26.1 0.5 1.5 18.3 0.5 4.0 0.2 6.2 5.2 29.1 2.6 1.0 0.3 1.7 0.7 2.0 0.0 2.6 0.1 0.9 0.8 0.3 1.0 2.6 0.8 17.0 1.2 7.1 1.2 2.7 20.7 4.4 2.1 53.3 0.3 1.1 0.5 0.1 0.7 1.0 0.6 0.7 2.3 0.1 3.0 3.9 19.2 1.0 12.8 15.8 0.1 0.2 0.0 0.0 190.6 20.1 36.4 25.0 4.5 3.2 0.3 0.0 1.3 13.3 13.3 42.7 27.3 5.5 17.0 0.1 2.8 0.0 1.7 0.0 0.0 0.0 1.7 0.3 21.4 7.4 7.2 0.0 0.0 8.1 0.2 3.2 0.0 169.2 20.8 1.2 9.5 9.9 20.7 0.1 0.0 7.0 0.0 10.1 5.1 0.1 13.6 308.9 21.8 28.3 86.8 4.6 0.2 16.2 0.4 8.6 15.4 0.1 0.0 0.1 4.0 0.1 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.5 1.5 1.7 0.7 0.9 0.8 1.2 0.5 0.6 1.0 0.7 0.0 9.5 3.9 0.3 132.4 29.9 2.4 120.1 4.1 66.1 79.6 1.0 0.0 5.6 9.2 0.0 91.7 1.5 1.7 0.0 0.3 0.3 7.8 18.7 2.0 3.0 0.0 0.0 0.0 59.7 7.4 1.5 16.0 0.0 0.0 0.7 0.0 7.8 0.0 0.0 1.7 10.2 0.3 8.2 0.0 0.0 1.6 21.4 3.7 0.0 0.3 0.0 0.0 0.0 1.0 0.6 0.0 3.8 18.6 0.0 0.0 5.2 0.0 0.0 0.5 2.1 0.0 1.8 81.0 149.3 105.6 1.3 0.0 1.0 18.5 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TFPT "amida, FB1, INO80F" ENSG00000105619 "TCF3 fusion partner" P0C1Z6 19 54107020-54115657 "Disease related genes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034958, HPA058534" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA034958: AB_10603036, HPA058534: AB_2683745" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (6.56e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.85e-1)" "unprognostic (2.85e-1)" "unprognostic (2.71e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.00e-2)" "unprognostic (2.61e-1)" "unprognostic (3.43e-1)" "unprognostic (3.66e-2)" 12.1 15.8 27.4 8.9 25.2 10.4 12.8 23.1 41.3 11.7 18.6 15.7 9.7 11.7 4.3 10.0 9.9 7.2 16.1 26.5 24.7 12.0 10.5 12.3 10.7 24.1 25.0 9.5 8.7 9.2 10.9 8.4 24.3 22.2 4.1 5.0 13.1 5.4 19.4 13.2 12.2 6.1 20.9 19.1 14.1 9.1 24.0 13.5 11.2 10.6 6.4 12.3 9.4 28.0 23.5 28.5 18.2 12.9 6.7 9.5 11.8 25.1 15.5 23.9 24.5 17.8 23.6 20.5 20.2 12.8 12.5 11.2 10.8 19.6 7.8 43.5 52.2 30.7 27.5 20.8 39.6 16.1 34.7 11.2 9.5 18.8 15.7 11.5 18.7 30.8 19.3 45.8 9.2 30.2 34.3 47.2 11.0 34.1 19.8 30.6 10.0 15.4 10.0 35.9 19.2 17.4 9.2 38.4 45.1 5.6 14.0 48.9 37.8 52.4 19.3 7.5 36.9 33.8 48.2 18.5 20.7 40.4 34.4 10.5 9.2 6.4 15.4 10.7 14.6 9.4 19.4 20.1 19.0 9.3 16.2 17.2 6.5 21.4 3.9 43.3 26.0 11.2 27.4 25.2 23.1 41.3 26.5 24.7 24.1 25.0 24.3 20.9 24.0 28.0 25.3 16.0 7.2 5.2 12.2 17.0 9.8 25.5 12.0 10.9 31.4 32.3 2.5 12.8 28.6 22.0 2.1 22.4 30.3 22.5 15.6 21.0 9.6 27.1 8.2 29.5 15.6 7.8 5.0 27.6 29.1 11.3 11.2 13.3 15.2 20.8 37.9 9.6 135.7 0.0 4.1 35.7 32.6 28.1 41.0 5.5 12.2 43.5 39.2 1.0 49.7 17.8 25.7 2.5 3.6 55.9 18.4 17.0 13.1 31.9 23.0 24.8 46.4 12.4 6.6 7.8 16.5 11.0 16.0 5.8 17.3 26.1 22.8 41.1 16.1 13.0 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Leydig cells: 92.2;Peritubular cells: 179.0;Sertoli cells: 223.5;Smooth muscle cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 100.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB020844 Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" Cytosol "CAB020844: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" 65.5 17.0 4.8 22.7 5.1 1.0 52.8 4.6 6.9 119.0 4.4 264.4 14.5 265.6 12.4 38.2 143.2 14.4 48.5 4.6 4.7 26.6 9.7 54.7 4.8 5.6 4.6 78.6 8.2 8.6 8.2 19.7 5.0 87.6 23.9 0.7 21.0 80.8 13.1 28.5 61.7 106.1 4.7 33.0 78.5 10.2 5.1 1.4 26.8 10.5 4.9 171.1 73.6 4.4 13.3 16.6 25.9 0.0 25.4 46.1 0.3 70.8 64.8 43.6 30.1 6.6 4.5 0.0 65.1 62.3 29.1 20.6 6.0 13.3 56.4 0.1 0.3 17.5 29.1 3.7 67.4 0.0 19.8 31.1 18.7 27.5 16.3 100.0 29.2 0.0 1.5 0.0 51.9 0.1 0.0 1.6 1.4 1.4 16.2 0.0 30.9 0.1 12.5 6.6 0.0 19.0 27.5 0.2 14.1 20.9 0.1 1.7 82.4 79.8 19.2 21.4 31.8 0.1 0.1 0.2 34.9 0.8 49.6 9.5 0.0 0.1 0.2 0.0 0.3 0.9 0.9 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.3 1.6 1.3 4.8 5.1 4.6 6.9 4.6 4.7 5.6 4.6 5.0 4.7 5.1 4.4 76.9 6.4 4.8 0.0 0.4 12.6 23.9 34.8 14.8 0.4 4.1 71.5 13.4 5.7 3.4 7.3 0.0 1.2 1.5 1.8 7.9 33.3 1.2 3.6 76.2 48.8 0.0 11.0 0.1 22.5 1.2 64.4 4.6 2.9 6.3 35.3 29.6 0.3 14.6 0.0 0.1 4.7 0.0 0.3 15.4 3.3 92.2 9.3 40.9 2.8 4.2 7.0 0.0 3.5 0.1 28.4 2.2 179.0 1.4 20.1 13.3 19.7 1.1 1.4 223.5 17.4 176.0 1.5 3.6 1.9 11.2 1.8 2.6 20.3 5.3 4.6 THBD CD141 ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 254.3;Endothelial cells: 200.6;Langerhans cells: 138.1;Leydig cells: 130.8;Macrophages: 130.9;Peritubular cells: 259.2;Squamous epithelial cells: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.8;granulocytes: 24.6;monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;CAPAN-2: 39.2;EFO-21: 33.5;HaCaT: 33.1;hTCEpi: 42.6;OE19: 29.8;THP-1: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 5550000 1300000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "CAB002425: AB_563497, HPA002982: AB_1078444" "unprognostic (1.96e-1)" "unprognostic (2.93e-3)" "unprognostic (8.70e-2)" "unprognostic (3.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (7.81e-3)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (7.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.58e-3)" "unprognostic (9.71e-2)" 65.4 11.4 2.0 19.6 1.8 15.5 25.5 1.6 3.2 16.7 3.4 16.5 5.5 12.6 3.1 36.8 27.5 26.5 31.0 2.4 3.0 19.7 9.7 56.7 14.5 4.1 2.7 6.9 13.2 9.9 20.4 28.5 2.8 8.0 5.9 0.2 10.8 4.6 40.7 71.4 20.0 15.6 3.0 43.6 30.8 7.6 8.5 5.1 35.5 17.5 8.0 20.8 21.0 2.4 11.5 9.9 0.3 0.0 24.3 1.4 0.2 0.2 0.0 0.0 0.0 0.0 39.2 0.0 33.5 3.4 1.7 33.1 0.0 1.8 0.0 0.0 0.1 0.1 1.0 0.0 4.7 0.0 0.2 1.1 42.6 0.7 2.8 23.0 11.0 0.0 4.2 0.0 0.9 0.8 0.0 4.2 0.1 29.8 1.6 0.0 0.0 4.9 0.2 16.2 0.7 0.0 9.4 1.2 17.4 2.9 0.0 24.8 21.7 0.1 0.6 3.2 0.0 0.0 0.0 0.0 2.0 5.8 0.8 0.0 4.1 0.0 0.0 9.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 24.6 2.0 8.7 10.8 0.0 2.0 2.0 1.8 1.6 3.2 2.4 3.0 4.1 2.7 2.8 3.0 8.5 2.4 254.3 22.4 21.4 0.0 2.0 34.3 10.4 9.5 23.3 0.1 3.9 5.3 16.8 1.5 21.3 0.0 0.0 3.2 16.9 0.0 0.0 1.8 0.9 1.9 1.8 200.6 0.0 2.7 0.3 0.2 37.1 46.1 2.6 7.2 7.6 0.2 65.3 0.8 14.9 0.0 0.7 0.4 4.1 32.4 138.1 4.9 130.8 130.9 16.0 1.0 8.1 0.0 0.0 0.0 0.0 9.0 0.0 259.2 2.3 4.5 0.0 0.3 2.5 0.0 6.6 51.4 39.0 0.2 1.0 237.3 98.6 42.4 3.2 2.8 0.1 58.2 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785503-2815807 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 136.6;Paneth cells: 160.6;Proximal enterocytes: 312.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 2000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB025497: , HPA035262: AB_2674541" "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 13.4 19.6 31.8 11.8 31.6 19.6 15.3 29.8 48.4 15.3 25.4 21.3 22.6 18.7 6.3 31.0 17.6 3.3 38.0 33.2 28.7 22.7 73.0 13.7 11.6 33.7 31.7 18.8 17.5 6.0 32.0 7.8 30.7 37.6 7.0 9.3 15.7 5.2 40.6 20.0 21.5 6.1 26.9 23.0 16.1 70.2 28.6 13.8 17.9 11.0 8.3 18.7 15.9 30.4 91.4 66.3 25.1 54.6 12.8 12.5 89.9 55.4 20.4 53.8 43.4 78.4 28.3 81.3 26.4 21.7 37.7 72.4 37.8 45.6 22.5 0.3 79.7 28.9 75.9 94.4 13.7 56.3 43.1 13.9 16.0 44.8 20.0 15.5 31.0 54.0 68.2 38.7 23.1 70.5 63.1 105.0 74.7 27.2 90.2 51.7 33.8 77.5 22.8 51.9 68.5 54.6 48.5 42.9 27.6 13.1 41.8 53.8 35.5 41.2 35.5 88.6 95.4 67.1 60.7 55.7 46.0 93.3 50.1 9.3 2.5 1.2 3.7 2.9 3.0 3.8 2.7 5.2 3.6 5.3 3.4 3.0 1.0 3.0 6.0 7.0 7.6 2.5 31.8 31.6 29.8 48.4 33.2 28.7 33.7 31.7 30.7 26.9 28.6 30.4 5.1 3.2 10.6 15.0 12.0 6.8 10.3 15.6 11.4 20.3 12.6 10.8 9.0 5.7 9.7 11.0 35.5 27.6 8.7 136.6 9.8 18.7 17.6 11.1 8.3 7.4 40.8 13.7 12.1 15.1 55.9 11.1 9.2 10.1 5.7 23.1 7.1 85.9 23.0 6.7 10.5 59.9 6.1 9.8 6.0 23.4 11.5 9.1 3.6 3.7 8.3 13.5 4.1 4.0 7.1 21.3 160.6 6.0 17.2 16.6 312.2 10.8 9.7 32.4 13.1 10.6 15.0 55.6 19.2 13.4 5.8 33.8 8.0 15.9 48.2 8.4 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIGD2 ENSG00000180346 "Tigger transposable element derived 2" Q4W5G0 4 89111533-89114901 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 25.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Hepatocytes: 21.0;Syncytiotrophoblasts: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 11.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 11.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054844, HPA071168" Uncertain Approved "Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" "HPA054844: AB_2682623, HPA071168: AB_2686353" "unprognostic (7.11e-2)" "unprognostic (8.02e-2)" "prognostic favorable (4.59e-4)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (5.42e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (8.47e-2)" "unprognostic (4.96e-2)" "unprognostic (9.83e-3)" "unprognostic (1.16e-1)" "unprognostic (8.94e-3)" "unprognostic (2.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.02e-4)" 2.8 1.9 1.9 3.2 1.9 2.5 10.4 4.7 2.1 3.9 3.9 3.4 6.8 2.4 4.0 2.7 1.7 2.8 1.6 1.7 2.4 5.4 25.4 3.1 4.5 2.0 2.5 2.1 3.6 7.1 3.5 8.6 2.1 3.8 4.1 13.2 10.7 2.5 1.9 2.4 4.8 1.9 1.8 3.5 4.4 3.7 2.4 5.5 5.6 3.1 4.5 3.0 2.7 2.3 15.2 7.0 7.5 9.0 8.1 6.2 3.3 9.0 11.0 8.5 7.1 14.1 14.4 7.3 4.7 3.6 6.1 4.7 8.2 13.8 11.4 12.7 2.6 8.6 7.7 6.8 24.0 4.0 5.9 15.4 13.4 3.4 12.2 7.9 3.2 9.6 11.1 12.3 10.6 5.8 7.6 4.6 9.0 16.2 2.3 11.5 13.1 10.0 7.4 28.7 35.6 7.2 8.8 27.8 11.5 9.9 9.8 8.1 2.5 10.9 10.1 3.5 6.9 19.7 6.4 5.5 9.6 7.0 9.4 11.7 1.3 0.1 1.9 1.9 0.9 1.2 0.9 1.4 1.5 1.0 0.9 1.4 0.0 2.2 1.0 0.2 1.0 0.9 1.9 1.9 4.7 2.1 1.7 2.4 2.0 2.5 2.1 1.8 2.4 2.3 1.9 0.0 0.5 1.3 1.8 0.3 5.9 1.7 7.4 4.5 4.9 3.3 3.5 7.2 5.5 3.7 10.4 15.9 1.3 1.2 1.9 2.7 1.4 6.3 3.0 2.6 2.4 1.7 1.3 5.7 10.5 1.7 4.6 6.3 0.0 2.8 2.2 21.0 4.9 0.0 1.9 2.9 0.0 2.4 1.1 0.8 1.5 3.5 0.0 0.0 4.3 2.7 1.0 1.5 2.3 3.8 1.9 1.2 2.4 2.3 8.3 10.2 1.5 7.2 0.0 1.5 2.7 2.3 8.0 3.6 0.4 39.0 2.5 2.1 3.2 1.6 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 818.9;Late spermatids: 1315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 99.9;BJ hTERT+: 98.7;BJ hTERT+ SV40 Large T+: 89.4;fHDF/TERT166: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" 9.3 15.7 18.4 16.4 45.2 67.9 8.7 22.3 27.4 9.6 20.2 9.9 8.4 14.3 5.9 17.6 12.9 16.6 8.0 27.5 21.6 6.9 5.6 12.5 15.9 31.7 21.4 32.3 6.4 10.6 24.2 19.7 32.2 5.6 10.5 24.7 10.9 8.4 23.1 18.9 11.3 14.5 26.1 18.5 14.1 108.0 25.4 27.8 10.4 10.3 19.9 18.7 12.8 64.0 0.0 19.0 70.7 0.5 11.4 9.6 21.2 99.9 98.7 89.4 34.4 2.8 10.3 7.4 0.2 154.3 13.7 20.8 5.0 18.3 39.2 38.2 30.8 0.0 9.1 0.4 13.8 21.4 13.0 11.3 12.6 26.1 5.2 25.2 23.9 14.0 1.5 21.3 28.6 0.7 29.4 9.4 22.5 11.9 4.8 25.7 35.9 7.4 5.5 2.7 28.5 41.5 14.7 1.9 0.1 32.8 0.0 25.1 36.4 34.8 0.1 0.8 5.0 14.4 25.0 10.9 12.3 18.0 16.6 24.2 4.4 17.1 4.8 6.3 5.9 1.3 2.5 3.6 2.9 1.7 1.5 2.5 11.7 3.2 4.9 1.0 0.8 2.6 18.4 45.2 22.3 27.4 27.5 21.6 31.7 21.4 32.2 26.1 25.4 64.0 108.9 6.4 19.4 77.4 91.9 121.0 57.2 50.6 167.4 76.8 76.0 92.8 15.9 84.4 45.6 14.7 127.2 77.2 228.1 163.5 3.9 13.4 818.9 262.0 230.0 59.7 25.2 22.3 150.8 22.0 67.1 71.4 137.1 158.7 21.0 34.8 53.2 14.1 51.1 218.7 33.3 117.3 61.1 167.9 70.4 1315.5 105.6 101.7 42.7 77.8 75.3 31.0 88.6 301.6 381.0 31.7 207.6 46.6 152.7 37.8 122.0 18.1 50.4 290.2 72.3 280.7 83.9 38.3 146.0 140.0 90.8 65.0 141.0 86.8 96.0 99.9 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TLR10 CD290 ENSG00000174123 "Toll like receptor 10" Q9BXR5 4 38772238-38782990 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 47.9" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 9.4;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 39.0;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 5 "B-cells: 39.0" "Group enriched" "Detected in some" 53 "Daudi: 68.6;REH: 22.9;U-698: 24.7" "Low region specificity" "Detected in many" HPA066755 Approved Centrosome,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol Centrosome "HPA066755: " "unprognostic (5.41e-5)" "unprognostic (2.41e-4)" "unprognostic (1.91e-3)" "unprognostic (8.22e-4)" "unprognostic (6.48e-2)" "unprognostic (9.98e-4)" "unprognostic (9.31e-2)" "unprognostic (8.76e-3)" "unprognostic (4.08e-3)" "unprognostic (7.26e-2)" "unprognostic (8.76e-2)" "unprognostic (6.90e-2)" "unprognostic (2.98e-3)" "unprognostic (3.90e-1)" "unprognostic (1.81e-2)" "unprognostic (3.14e-3)" "unprognostic (1.88e-2)" 0.9 0.3 1.0 15.8 0.9 1.4 0.8 1.0 1.2 0.2 0.5 1.4 1.2 0.4 0.4 0.5 0.5 1.3 0.1 0.9 1.2 0.2 0.4 0.8 42.3 1.9 1.5 0.0 0.1 0.1 0.2 0.2 2.0 1.0 1.9 0.1 1.4 0.4 0.2 0.5 10.0 0.3 2.0 24.3 2.9 0.1 1.4 5.1 0.4 0.1 47.9 2.7 0.1 2.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 22.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.0 0.1 0.0 24.7 0.0 0.1 0.0 0.3 0.4 0.9 0.0 2.8 0.0 39.0 0.0 0.0 6.4 24.0 0.1 0.1 1.3 0.1 3.6 7.2 0.0 1.8 1.0 0.9 1.0 1.2 0.9 1.2 1.9 1.5 2.0 2.0 1.4 2.2 0.2 0.0 1.1 0.0 57.2 0.4 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.2 2.7 0.3 0.0 0.0 0.9 0.0 0.2 1.3 0.0 0.4 0.3 0.8 0.0 0.3 0.2 0.0 1.9 0.8 0.0 0.0 4.5 0.0 16.9 1.0 0.2 0.0 4.5 0.1 0.0 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Club cells: 23.3;Glandular and luminal cells: 25.6;Kupffer cells: 29.5;Microglial cells: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Cell line enhanced" "Detected in some" "A-431: 2.1;HaCaT: 3.2;OE19: 1.8;SK-BR-3: 2.0;T-47d: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" 3.5 1.9 2.6 4.7 2.2 0.5 8.6 2.5 2.4 6.0 2.3 2.0 1.6 2.1 2.6 4.9 5.1 4.5 1.7 2.3 2.7 4.1 1.6 6.2 4.3 3.7 3.5 20.2 4.0 4.4 0.7 3.4 3.6 3.3 2.1 0.7 10.3 2.4 1.4 2.0 2.1 2.6 3.1 2.9 4.1 1.8 3.4 2.5 1.9 1.6 5.0 4.0 2.4 5.0 2.1 0.2 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.0 3.2 0.0 0.2 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.2 0.1 0.8 0.4 0.0 0.0 0.3 0.5 0.1 1.1 1.8 0.0 0.0 0.0 0.1 0.9 0.4 0.8 0.3 0.6 2.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.2 0.0 30.8 0.4 0.2 28.1 0.4 0.2 1.5 0.4 23.4 0.1 2.3 0.7 25.3 0.4 12.4 0.3 1.2 10.9 2.6 2.2 2.5 2.4 2.3 2.7 3.7 3.5 3.6 3.1 3.4 5.0 1.0 3.2 17.0 0.0 0.2 0.5 5.8 18.9 4.6 0.1 10.6 5.3 1.7 14.3 23.3 22.0 2.1 1.5 0.3 0.4 3.9 5.9 4.6 13.6 2.0 2.1 1.2 0.0 0.5 3.8 0.3 7.7 3.1 25.6 2.5 4.6 0.7 0.7 18.1 0.0 1.0 0.6 6.1 29.5 3.1 5.7 9.3 22.4 3.6 23.4 14.4 1.4 0.0 1.5 0.1 2.4 0.1 8.6 0.1 3.0 0.5 0.1 11.0 0.2 0.0 4.2 4.1 5.4 5.5 15.9 1.6 0.8 1.7 4.1 1.5 6.3 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 44.9;dendritic cells: 52.3;granulocytes: 41.2;Langerhans cells: 44.6;NK-cells: 85.5;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 46.3;HL-60: 63.0;HMC-1: 119.9;Karpas-707: 103.9;RPMI-8226: 66.6;U-266/70: 49.3;U-937: 51.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" 7.8 3.0 3.6 56.0 4.4 91.8 3.7 3.7 5.1 3.7 3.5 8.2 10.3 2.5 0.7 4.8 4.0 7.4 2.7 3.6 4.8 5.2 7.1 18.4 100.5 5.8 4.7 1.3 2.0 0.5 2.2 3.9 5.6 4.9 4.5 0.1 5.8 1.3 1.8 3.6 54.6 2.4 5.0 117.0 10.4 1.2 7.8 60.1 6.4 0.9 46.7 6.4 5.0 7.2 0.5 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 46.3 2.0 0.0 0.1 3.4 0.0 0.1 0.0 0.0 0.1 16.4 0.1 0.8 0.0 63.0 119.9 0.0 0.0 0.0 0.0 0.0 0.0 22.1 4.0 103.9 0.0 1.3 20.9 2.8 0.2 3.5 0.5 1.4 0.3 66.6 0.0 0.2 0.0 0.1 0.0 2.2 0.6 0.1 6.9 12.7 0.1 0.0 0.1 0.1 0.0 49.3 2.0 4.6 0.1 51.9 0.1 2.6 2.0 6.6 13.4 3.4 9.7 5.5 10.8 13.3 2.3 4.8 9.4 8.6 3.3 7.5 7.9 2.1 6.5 5.5 3.6 4.4 3.7 5.1 3.6 4.8 5.8 4.7 5.6 5.0 7.8 7.2 3.6 3.2 10.2 1.0 44.9 5.4 10.4 4.9 4.6 0.2 1.2 1.5 1.9 1.5 6.5 0.0 0.0 0.4 52.3 3.7 0.0 1.0 0.7 1.0 0.6 3.2 1.2 17.1 0.4 1.3 1.4 2.3 2.0 1.8 41.2 0.1 5.7 0.5 30.5 0.0 0.4 1.4 14.2 28.2 44.6 0.5 0.0 22.0 7.2 24.4 30.2 0.2 85.5 1.0 2.7 0.6 3.6 0.4 20.2 2.9 0.9 0.4 2.1 0.2 0.0 0.3 2.0 0.4 0.6 8.4 4.5 0.5 68.6 2.7 7.0 10.7 TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 409.4" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA049314: AB_2680708, HPA076949: AB_2686820" "prognostic unfavorable (7.71e-4)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (8.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.03e-3)" "unprognostic (2.42e-2)" "unprognostic (2.49e-1)" "unprognostic (4.85e-1)" "unprognostic (9.06e-2)" "unprognostic (8.09e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.16e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" 25.9 26.2 19.6 23.1 19.2 37.0 66.4 21.5 20.5 56.6 30.6 49.9 25.4 38.3 138.7 132.3 38.7 37.8 41.9 20.8 31.9 34.7 12.4 30.9 26.0 22.4 22.0 30.9 246.7 54.9 89.6 42.4 26.5 60.0 55.4 11.3 409.4 54.6 4.6 106.8 26.6 37.3 21.6 32.4 73.1 35.0 22.6 23.1 76.3 7.2 37.8 48.7 75.1 25.1 68.1 169.0 31.9 63.6 220.3 167.5 69.0 153.0 206.7 103.3 126.9 141.4 123.3 31.5 117.3 236.0 135.9 124.5 95.7 98.5 53.0 62.7 145.6 104.5 143.0 110.3 131.5 112.2 200.4 126.5 144.4 59.6 86.9 123.5 120.8 105.9 47.1 0.6 101.4 144.3 32.1 106.0 45.7 251.6 92.2 39.1 47.4 158.9 94.2 51.4 99.4 48.8 80.6 162.1 159.3 103.5 141.5 81.7 98.5 85.2 75.7 2.2 111.4 61.7 78.8 44.1 109.8 180.7 103.1 74.9 69.8 95.1 58.1 85.3 62.7 75.5 57.2 63.9 106.7 63.6 71.4 69.1 6.0 61.4 95.7 109.1 73.1 92.2 19.6 19.2 21.5 20.5 20.8 31.9 22.4 22.0 26.5 21.6 22.6 25.1 9.9 28.9 43.6 6.8 41.2 95.8 109.4 125.6 64.9 14.9 153.8 132.8 16.9 55.8 108.5 57.0 8.4 167.8 40.7 67.7 23.5 143.4 48.9 31.6 39.6 31.7 83.9 33.7 10.0 250.5 294.5 68.1 54.6 70.4 47.0 44.0 65.7 6.4 100.5 13.5 10.2 219.3 87.5 52.7 54.4 118.6 49.7 49.2 85.4 9.4 60.0 38.0 44.3 17.1 12.9 173.3 79.9 27.4 71.1 165.2 43.9 28.9 37.7 17.0 19.7 25.6 57.0 51.1 60.3 104.7 121.8 172.4 30.4 64.6 126.4 200.1 TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.8;Endothelial cells: 25.5;Fibroblasts: 40.7;Leydig cells: 40.7;Peritubular cells: 52.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 28.9;ASC TERT1: 19.5;HHSteC: 44.8;HSkMC: 20.6;U-87 MG: 13.9;WM-115: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" 40.8 5.0 5.4 3.2 5.5 0.0 27.6 4.3 9.0 15.8 6.0 14.5 6.7 3.6 36.6 6.5 8.0 7.3 18.7 5.1 7.0 1.9 7.0 192.5 1.2 5.5 7.0 26.5 2.3 0.8 11.2 54.1 6.0 10.3 11.6 0.4 8.0 24.7 9.7 4.6 13.2 5.5 4.6 6.9 30.2 2.7 8.1 1.1 7.5 14.1 0.6 11.1 8.2 4.7 0.0 0.0 5.9 0.0 28.9 19.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 44.8 0.0 0.0 20.6 0.0 1.4 0.1 0.2 0.0 0.3 1.0 0.1 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 8.7 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 1.9 3.9 0.0 0.8 0.0 0.1 13.9 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.5 4.3 9.0 5.1 7.0 5.5 7.0 6.0 4.6 8.1 4.7 57.8 0.0 3.6 2.3 0.1 2.5 0.3 0.0 1.2 0.7 0.4 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.1 4.0 25.5 0.0 0.0 0.1 0.0 0.0 40.7 1.5 0.2 1.3 0.1 7.1 15.2 0.1 0.0 1.6 0.0 0.0 0.0 4.9 0.5 40.7 0.2 7.2 1.9 0.0 0.0 0.0 17.1 0.0 0.1 0.0 52.6 0.0 0.1 0.0 3.4 0.0 0.1 32.9 10.3 15.1 0.1 0.2 0.7 2.6 0.1 0.5 0.3 0.0 0.3 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM132D "KIAA1944, MOLT, PPP1R153" ENSG00000151952 "Transmembrane protein 132D" Q14C87 12 129071725-129904025 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 5.5" "Group enriched" "Detected in some" 60 "Excitatory neurons: 448.6;Inhibitory neurons: 523.0;Oligodendrocyte precursor cells: 573.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.5;MOLT-4: 4.6;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010739 Approved NA NA 110000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA010739: AB_2204753" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (5.39e-1)" "unprognostic (1.47e-2)" "unprognostic (2.89e-1)" "unprognostic (3.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.31e-4)" 0.0 0.1 0.9 0.1 5.5 0.1 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 4.6 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 5.5 0.0 4.9 2.5 1.0 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 1.8 0.0 448.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 523.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 8.4 0.0 0.2 0.0 573.0 7.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TMEM156 FLJ23235 ENSG00000121895 "Transmembrane protein 156" Q8N614 4 38966744-39032922 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in many" "B-cells: 99.8;Microglial cells: 68.4;NK-cells: 28.8;Plasma cells: 123.1;T-cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 74.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 39.6;GAMG: 29.6;HBEC3-KT: 84.8;hTERT-HME1: 64.0;NB-4: 35.2;PC-3: 37.3;U-698: 45.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.09e-4)" "unprognostic (7.36e-3)" "unprognostic (3.31e-3)" "unprognostic (4.17e-3)" "unprognostic (1.82e-1)" "unprognostic (1.01e-3)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (9.45e-3)" "unprognostic (5.17e-2)" "unprognostic (8.73e-4)" "unprognostic (3.89e-1)" "unprognostic (1.74e-2)" "unprognostic (3.92e-4)" "unprognostic (9.06e-2)" 0.4 1.7 1.7 9.0 1.6 1.9 1.1 2.0 1.8 0.5 1.7 1.7 1.8 0.5 0.2 0.5 0.5 1.9 0.3 1.9 1.9 0.5 2.8 0.9 23.6 2.7 2.2 0.4 0.3 0.2 0.1 0.1 2.8 0.6 1.9 0.5 0.9 0.5 0.5 0.4 5.1 0.4 2.3 11.1 2.6 0.2 1.9 5.1 0.4 0.0 26.8 3.0 0.2 3.4 2.4 23.9 0.2 0.2 0.0 0.6 0.2 0.1 6.4 0.0 0.0 0.2 0.3 39.6 0.3 0.0 29.6 0.2 0.2 84.8 0.3 0.4 0.0 2.1 7.7 0.5 13.3 16.8 0.3 0.1 4.2 1.7 64.0 4.9 7.3 6.5 5.8 0.2 2.8 0.2 3.1 35.2 0.1 0.9 37.3 0.8 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.1 1.2 17.9 2.9 0.5 0.2 0.7 0.2 0.1 45.3 5.0 15.2 0.1 16.8 0.8 48.6 12.2 0.3 14.3 74.8 20.7 12.2 8.4 59.9 8.0 10.4 1.8 12.5 0.3 12.4 15.4 8.3 1.7 1.6 2.0 1.8 1.9 1.9 2.7 2.2 2.8 2.3 1.9 3.4 0.6 0.0 1.8 0.7 99.8 0.5 0.8 0.5 0.0 0.6 2.3 2.4 0.3 17.2 1.9 0.0 0.0 0.1 22.1 0.0 0.0 0.5 1.3 0.3 1.1 3.3 0.0 4.2 0.6 0.0 1.2 0.8 1.5 0.2 0.0 0.0 2.9 0.4 1.6 1.7 0.7 0.2 2.0 22.8 2.7 2.8 0.0 8.4 10.6 68.4 2.7 0.1 28.8 0.5 2.5 1.1 0.0 0.0 123.1 0.8 0.0 0.4 1.5 0.5 0.0 1.4 0.6 0.8 0.1 0.0 0.6 0.3 30.2 0.1 0.3 0.8 TMEM158 "p40BBp, RIS1" ENSG00000249992 "Transmembrane protein 158" Q8WZ71 3 45224466-45226287 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;endometrium 1: 69.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 24.5;Breast myoepithelial cells: 24.5;Endometrial stromal cells: 61.0;Muller glia cells: 87.4" "Cancer enhanced" "Detected in many" "glioma: 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 336.1;GAMG: 111.9;U-138 MG: 138.9;U-87 MG: 455.3" "Region enhanced" "Detected in all" "basal ganglia: 95.5" "Low region specificity" "Detected in all" HPA074974 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" "HPA074974: AB_2732274" "unprognostic (3.84e-1)" "unprognostic (9.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.77e-2)" "unprognostic (5.73e-2)" "unprognostic (3.31e-2)" "unprognostic (4.67e-3)" "unprognostic (6.23e-2)" "unprognostic (6.41e-2)" "unprognostic (1.84e-3)" "prognostic favorable (6.43e-5)" "prognostic unfavorable (5.42e-9)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-2)" "unprognostic (4.49e-3)" 2.6 9.2 20.3 3.8 33.3 1.9 1.6 7.5 23.0 8.6 8.5 8.1 0.7 69.5 2.2 18.2 3.9 6.4 0.7 22.4 23.9 3.6 0.7 1.6 0.5 10.6 22.5 1.4 1.9 0.2 12.2 0.8 10.4 13.2 1.9 1.5 1.4 22.7 2.0 2.4 1.9 17.0 15.2 0.4 1.9 2.5 27.4 0.2 0.7 0.7 1.1 8.7 2.8 13.8 12.9 2.1 4.4 0.8 7.7 18.3 3.7 31.6 336.1 17.0 27.5 0.7 0.8 0.1 1.6 10.5 111.9 17.2 5.1 1.4 50.2 0.8 2.0 0.0 6.1 0.1 10.7 2.5 6.1 24.6 0.6 33.7 2.7 39.2 1.8 0.0 80.3 0.9 30.4 0.5 0.0 22.3 37.8 0.3 46.5 0.0 1.0 4.9 6.7 11.9 6.1 1.4 12.2 0.4 2.1 3.4 0.3 4.3 5.1 138.9 10.4 88.4 110.2 0.0 0.1 0.0 455.3 12.6 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.3 33.3 7.5 23.0 22.4 23.9 10.6 22.5 10.4 15.2 27.4 13.8 1.6 0.0 0.5 1.6 0.4 24.5 6.1 2.1 2.8 4.4 13.1 24.5 1.0 1.5 0.8 9.2 0.0 0.1 0.5 0.6 0.0 2.9 0.2 10.8 61.0 1.3 7.7 0.0 8.7 0.4 0.1 9.3 0.5 4.2 0.0 0.7 2.5 2.7 5.1 1.7 5.7 0.6 2.0 0.8 16.4 0.7 8.4 6.4 0.0 1.9 1.4 87.4 0.0 6.0 1.2 1.0 0.5 0.0 0.0 1.7 0.0 0.2 0.4 2.9 0.0 4.9 8.3 0.3 0.5 1.0 10.5 0.3 0.6 16.7 0.7 4.2 TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.49e-1)" "unprognostic (1.18e-1)" "unprognostic (2.95e-2)" "unprognostic (1.52e-3)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (7.97e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "prognostic favorable (2.36e-9)" "unprognostic (4.37e-2)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (1.53e-3)" 8.2 9.8 7.7 10.6 10.6 36.6 6.0 9.2 9.0 7.7 7.9 12.1 14.5 8.0 6.0 8.4 7.6 7.8 7.2 7.4 9.3 9.2 12.7 8.0 11.9 11.3 10.2 10.2 10.2 3.9 8.7 10.2 9.9 7.6 10.1 14.9 6.5 3.2 3.7 7.8 13.7 6.3 9.3 9.2 7.3 17.4 8.5 6.8 9.7 4.9 9.7 8.1 7.8 16.9 14.2 17.1 21.8 22.3 9.5 7.7 38.9 9.2 5.2 7.4 11.3 35.3 30.7 19.6 17.0 4.4 16.4 25.9 18.3 8.9 13.0 12.0 11.4 10.6 16.4 22.4 6.3 25.3 27.3 6.7 6.8 12.5 9.4 8.7 6.5 22.7 21.8 15.2 3.9 28.8 22.3 16.8 26.1 17.2 9.2 43.5 8.5 15.7 5.1 18.3 12.8 14.9 22.4 7.0 12.6 25.6 9.4 11.6 9.6 12.6 21.4 10.1 10.2 13.7 17.3 60.3 9.8 14.7 14.4 14.5 26.6 38.2 27.9 29.1 36.6 28.9 29.1 31.8 24.0 28.8 30.9 27.3 33.3 25.4 26.9 26.8 23.1 21.6 7.7 10.6 9.2 9.0 7.4 9.3 11.3 10.2 9.9 9.3 8.5 16.9 39.7 19.2 15.0 20.5 49.0 19.9 45.7 37.8 26.7 25.6 37.7 27.1 9.3 40.0 25.3 20.2 37.5 73.0 65.0 86.2 25.4 26.8 40.5 62.5 23.6 37.2 34.1 17.1 17.6 19.3 51.5 24.3 16.8 67.7 28.6 57.3 35.3 24.2 37.2 37.0 15.9 37.6 22.4 31.8 29.7 8.7 24.2 38.3 21.4 11.2 41.2 43.7 42.2 24.1 29.8 23.3 67.6 21.4 29.2 57.5 53.5 30.2 32.4 38.3 32.9 19.9 20.1 88.5 61.8 19.7 20.0 53.4 49.0 36.7 56.0 67.8 TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 11.3;parathyroid gland: 11.9;tongue: 12.2" "Group enriched" "Detected in many" 5 "Astrocytes: 175.0;Excitatory neurons: 584.8;Inhibitory neurons: 566.2;Oligodendrocyte precursor cells: 306.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 6.0;HDLM-2: 5.7;NTERA-2: 5.1;RPTEC TERT1: 8.2;SCLC-21H: 6.4;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" 0.3 1.4 3.7 0.6 5.4 0.0 0.5 0.2 7.4 0.3 0.0 0.8 0.0 0.8 0.4 0.7 0.3 0.3 11.3 7.0 5.0 1.3 0.0 0.3 1.4 1.5 5.9 0.1 0.9 11.9 4.2 0.0 5.6 2.3 0.3 5.5 1.2 0.5 4.6 0.2 0.4 1.0 0.6 0.7 0.3 0.5 5.2 1.4 8.5 12.2 3.1 0.5 0.2 1.9 0.0 0.1 0.0 0.0 0.5 0.2 1.5 0.1 2.3 0.7 0.8 0.0 0.0 1.9 2.0 0.1 0.5 0.0 6.0 0.0 1.9 5.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 5.1 0.0 0.0 0.4 0.9 2.6 8.2 2.4 6.4 3.9 0.1 0.2 0.9 1.2 0.8 0.0 0.0 0.1 0.9 2.7 0.0 0.0 0.0 0.0 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.2 7.4 7.0 5.0 1.5 5.9 5.6 0.6 5.2 1.9 1.3 0.0 0.0 175.0 0.0 0.5 0.7 0.9 0.6 25.5 1.4 0.5 48.7 0.0 1.3 1.8 2.1 0.0 0.0 0.0 1.9 0.1 1.3 0.2 0.1 1.2 0.0 0.0 584.8 0.4 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 30.3 566.2 0.0 2.0 0.0 0.0 1.6 0.0 0.1 1.8 24.4 0.0 4.2 0.0 306.1 81.3 0.8 0.0 0.7 0.0 2.2 0.0 3.4 0.2 1.8 0.0 3.9 0.8 1.4 0.7 2.9 0.1 0.3 0.3 0.2 0.1 2.0 TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" Nucleoplasm "HPA014717: AB_1844373, HPA024110: AB_2204898" "prognostic unfavorable (9.52e-4)" "unprognostic (5.38e-3)" "unprognostic (9.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (2.91e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (3.10e-1)" "unprognostic (3.27e-2)" "unprognostic (5.06e-2)" "prognostic favorable (2.33e-14)" "unprognostic (2.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (9.30e-2)" 12.0 15.2 4.9 7.2 5.9 6.6 13.2 7.5 7.0 9.9 7.1 11.5 9.7 10.5 9.0 8.8 11.2 10.3 12.6 4.8 5.2 48.3 45.2 10.6 8.9 4.7 5.5 24.5 22.3 24.6 5.1 10.8 5.0 22.1 13.3 10.7 14.5 8.4 15.0 5.4 9.3 8.6 4.6 9.1 10.5 9.8 4.8 6.6 26.8 17.0 7.7 8.5 5.4 6.2 13.5 19.9 7.1 18.0 18.1 6.4 16.5 20.1 29.4 20.5 22.8 11.7 21.6 29.5 11.7 13.0 33.4 11.8 26.8 20.6 23.6 19.2 13.8 16.4 14.1 13.4 46.1 41.0 21.2 23.3 42.8 18.4 37.4 17.8 17.0 15.6 28.4 48.1 25.4 29.4 7.1 12.0 14.8 28.1 16.9 16.0 6.2 27.1 16.4 19.6 15.2 15.9 31.4 49.1 31.9 10.4 23.9 18.5 12.6 9.0 11.1 28.6 23.0 46.9 67.0 40.8 21.6 22.2 36.6 2.9 16.6 4.8 12.1 14.9 16.3 26.7 9.4 12.6 15.7 20.2 10.4 12.6 1.7 18.7 8.3 16.3 8.5 10.7 4.9 5.9 7.5 7.0 4.8 5.2 4.7 5.5 5.0 4.6 4.8 6.2 12.3 32.1 36.2 18.9 24.0 9.7 18.4 10.5 10.2 33.0 21.5 15.7 35.0 42.9 19.1 55.2 16.7 31.4 15.4 17.0 11.7 21.0 26.4 11.2 17.0 19.0 21.7 10.1 16.4 25.8 20.5 18.9 7.7 15.5 40.4 26.1 27.8 77.7 38.2 37.0 16.5 18.2 6.1 27.4 17.7 11.1 39.7 22.3 28.4 11.2 21.3 35.8 28.8 14.6 20.9 11.5 14.3 33.4 11.8 33.7 26.3 63.4 10.9 27.1 6.6 30.7 20.7 17.8 18.3 12.0 12.9 33.7 15.9 27.1 24.0 14.2 TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.5;Distal enterocytes: 23.3;Endometrial stromal cells: 18.6;Enteroendocrine cells: 24.6;Granulosa cells: 49.9" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 40.8;hTEC/SVTERT24-B: 67.1;hTERT-RPE1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" 5.7 17.1 1.7 3.9 2.5 0.1 5.9 0.1 2.2 11.1 0.0 11.1 7.3 39.3 5.3 1.2 12.9 6.4 0.6 4.5 2.7 13.6 0.4 6.8 3.8 0.9 4.6 15.6 1.5 0.8 5.3 3.3 1.5 2.7 22.3 11.2 1.6 1.4 0.6 2.0 8.3 18.7 0.8 1.0 6.3 2.7 3.8 4.7 5.6 0.4 3.4 5.6 3.5 0.8 0.1 0.1 0.2 0.0 11.7 14.6 0.1 10.6 13.0 11.1 19.6 16.6 0.0 0.0 0.0 22.3 2.5 2.5 1.0 0.0 40.8 15.5 0.0 0.0 0.0 0.8 5.3 0.3 0.0 16.7 0.0 67.1 13.3 33.5 0.4 0.3 0.0 1.5 5.2 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 13.4 12.5 4.0 1.1 1.9 8.2 0.0 0.0 7.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.8 0.4 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 1.7 2.5 0.1 2.2 4.5 2.7 0.9 4.6 1.5 0.8 3.8 0.8 0.5 0.0 0.5 1.3 0.2 2.0 0.1 0.1 1.2 26.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.5 0.4 23.3 0.0 0.0 2.0 5.2 18.6 0.8 24.6 2.7 7.1 0.0 1.7 3.6 2.0 0.7 0.0 49.9 0.0 0.0 0.2 13.5 4.3 1.6 0.0 0.0 0.9 1.8 5.9 0.3 1.8 1.9 0.0 0.5 0.0 1.0 0.3 0.1 6.0 10.5 3.3 0.0 4.6 9.9 0.0 2.1 0.0 0.8 8.4 3.3 2.6 0.1 1.4 0.5 5.8 11.3 4.0 0.1 TMEM220 ENSG00000187824 "Transmembrane protein 220" Q6QAJ8 17 10699015-10730023 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 103.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 173.3;Proximal enterocytes: 576.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 9.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.71e-2)" "unprognostic (4.60e-2)" "unprognostic (6.31e-3)" "unprognostic (4.04e-3)" "unprognostic (1.05e-3)" "unprognostic (1.84e-4)" "prognostic favorable (2.23e-5)" "unprognostic (4.58e-2)" "unprognostic (4.96e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.97e-1)" "unprognostic (4.34e-3)" "unprognostic (2.25e-1)" "unprognostic (2.63e-2)" "unprognostic (7.80e-3)" "unprognostic (5.97e-2)" 8.6 10.9 3.3 4.9 3.8 5.8 7.2 3.3 3.3 6.4 5.5 8.2 15.7 6.9 4.5 4.3 6.1 5.1 5.1 3.3 3.7 10.3 103.8 5.5 6.2 4.2 3.8 6.9 9.5 3.6 3.2 3.2 4.7 21.7 4.9 19.0 5.5 7.8 8.1 6.6 26.8 3.8 4.4 6.5 13.0 9.1 3.9 1.2 13.0 0.8 1.9 5.9 5.0 4.6 0.5 3.1 1.1 7.2 4.4 4.4 0.7 6.0 6.6 4.2 5.7 0.0 0.3 0.7 0.4 4.0 0.2 0.4 2.8 0.2 3.0 0.3 1.2 0.4 0.1 2.7 6.7 0.8 0.7 3.0 0.3 1.3 0.3 0.8 1.9 2.7 0.3 0.2 2.6 0.4 1.1 1.3 4.4 0.4 0.0 4.4 0.2 0.5 9.8 0.2 0.4 5.5 0.3 0.1 0.7 1.5 0.3 1.6 4.4 0.2 0.9 2.2 0.4 0.7 0.3 0.2 4.3 1.1 0.4 1.6 2.1 2.1 0.7 1.6 0.9 4.0 1.8 1.1 2.6 9.0 7.4 5.2 1.6 4.2 0.7 1.9 0.4 1.7 3.3 3.8 3.3 3.3 3.3 3.7 4.2 3.8 4.7 4.4 3.9 4.6 10.1 3.2 11.0 18.3 7.5 9.6 17.7 9.2 23.3 2.5 20.9 26.4 11.6 57.2 9.9 18.4 8.4 12.0 3.1 41.3 21.5 18.0 99.0 6.1 16.3 8.1 3.0 21.7 1.4 23.6 20.6 16.3 33.6 7.6 40.0 13.4 16.1 173.3 24.0 0.0 2.8 32.6 4.1 13.5 6.4 22.2 18.0 13.1 24.9 12.2 4.6 55.0 5.2 17.6 1.6 12.6 32.5 9.8 6.6 36.5 576.7 31.7 6.9 23.6 19.7 17.2 12.7 90.6 8.7 20.7 8.0 4.5 3.0 30.0 21.1 22.3 TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 33.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 81.1;Enteroendocrine cells: 23.4;Intestinal goblet cells: 28.8;Paneth cells: 48.1;Proximal enterocytes: 96.5;Undifferentiated cells: 19.0" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "MOLT-4: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045096 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" 0.7 0.6 0.3 1.7 0.3 0.5 0.4 0.8 0.5 0.5 0.4 14.1 21.8 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.1 0.2 0.1 0.7 0.3 0.1 0.0 0.3 0.5 0.1 0.0 1.5 0.2 0.1 14.0 0.3 0.1 0.2 0.3 0.3 33.5 1.0 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.7 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.3 0.2 0.0 0.2 0.9 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.1 0.2 10.3 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.8 0.5 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.7 0.2 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.3 7.3 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.1 81.1 0.0 0.1 1.1 0.1 0.1 0.2 23.4 0.4 0.4 0.9 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.0 7.2 0.0 0.4 28.8 0.0 4.8 0.8 1.1 0.0 5.9 0.0 3.7 0.0 0.1 0.0 0.0 0.6 0.7 48.1 0.0 0.0 0.4 96.5 0.0 0.0 0.9 0.0 0.7 0.3 0.4 0.1 0.2 0.0 0.3 0.4 0.2 19.0 0.6 TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 113.5;Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" 16.6 22.9 7.3 6.4 7.8 2.7 16.9 7.9 10.0 15.5 8.2 22.9 10.3 14.2 16.5 13.1 14.7 6.7 25.6 7.6 7.6 33.2 17.2 17.1 8.0 7.7 7.8 14.2 21.2 10.3 19.8 6.9 7.8 25.7 12.5 20.7 19.6 9.2 30.6 13.7 18.1 6.8 7.4 15.9 21.8 8.4 8.1 8.6 17.6 12.4 6.9 17.2 12.8 9.0 11.0 12.1 15.3 16.1 17.2 7.3 9.4 7.9 8.2 12.7 16.2 7.8 11.1 12.1 12.9 7.9 15.9 15.9 17.8 12.6 17.7 9.3 13.4 10.9 8.8 18.3 15.2 16.0 14.7 9.3 14.6 10.0 16.2 6.8 12.2 13.5 9.3 12.0 11.6 52.5 10.2 12.8 8.3 28.0 11.6 4.7 16.0 11.3 16.6 23.6 12.9 13.4 11.7 6.0 36.9 12.4 17.7 11.4 5.0 6.1 10.8 14.6 9.4 9.3 16.0 11.8 11.4 6.1 9.1 6.8 9.7 13.6 3.9 9.4 2.9 4.7 4.6 4.4 8.0 5.5 5.2 5.9 10.5 5.3 13.0 7.3 4.1 4.2 7.3 7.8 7.9 10.0 7.6 7.6 7.7 7.8 7.8 7.4 8.1 9.0 13.4 3.2 14.4 5.2 22.4 23.2 37.9 33.6 13.1 14.8 41.1 39.1 22.5 32.9 22.0 31.3 27.1 36.6 16.5 44.8 113.5 30.3 1.8 33.1 16.3 11.9 15.0 11.3 5.9 26.6 21.1 16.6 20.9 35.7 17.2 15.2 8.9 19.2 110.1 13.5 7.8 36.1 26.4 28.4 20.0 2.3 11.8 39.6 32.0 2.8 16.2 34.8 12.3 5.0 13.8 17.7 23.8 10.9 13.1 43.3 31.7 69.6 17.2 30.6 39.5 13.9 23.2 4.5 17.8 18.1 31.1 27.4 16.1 17.6 30.9 36.4 TMEM252 "C9orf71, MGC34760" ENSG00000181778 "Transmembrane protein 252" Q8N6L7 9 68536580-68540883 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 22.0;kidney: 35.7" "Group enriched" "Detected in some" 5 "Proximal enterocytes: 21.6;Proximal tubular cells: 20.6" "Cancer enriched" "Detected in many" 17 "renal cancer: 35.7" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Immune cell enriched" "Detected in single" 8 "neutrophil: 4.1" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.1" "Cell line enhanced" "Detected in some" "PC-3: 1.2;RPTEC TERT1: 2.2;SK-BR-3: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA079457 Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA079457: " "unprognostic (2.64e-1)" "unprognostic (3.28e-3)" "unprognostic (3.72e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.64e-2)" "unprognostic (6.42e-2)" "prognostic favorable (1.75e-7)" "unprognostic (7.63e-2)" "unprognostic (6.15e-2)" "unprognostic (7.66e-2)" "unprognostic (2.50e-1)" 1.1 2.9 0.1 1.1 0.0 0.0 0.6 1.2 0.0 1.5 0.0 8.4 1.6 5.5 0.0 6.0 3.3 1.3 4.5 0.0 0.0 35.7 1.6 0.3 0.3 0.0 0.1 0.5 0.1 0.0 0.0 0.2 0.1 2.8 0.2 1.3 0.2 0.0 1.3 0.5 22.0 0.0 0.1 0.5 2.0 0.1 0.4 0.0 0.4 0.2 0.0 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.7 0.0 2.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 20.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 10.3;Breast glandular cells: 8.8;Endometrial stromal cells: 8.9;Glandular and luminal cells: 8.8;Granulosa cells: 9.6;Hofbauer cells: 8.9;monocytes: 19.1;Syncytiotrophoblasts: 8.8;Theca cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 7.3 7.7 11.0 6.9 12.7 3.6 7.5 2.9 16.6 6.5 6.4 6.9 3.4 6.8 6.3 4.3 4.7 3.7 3.3 14.4 6.1 3.3 5.3 5.2 9.5 4.4 5.3 8.5 4.7 14.1 4.1 4.8 5.3 12.2 5.4 4.5 8.9 6.5 4.6 4.2 6.3 6.8 5.3 13.3 7.2 3.9 6.5 8.6 6.2 4.3 9.4 6.3 5.1 11.3 4.7 7.1 3.8 8.2 10.1 7.6 2.9 4.3 7.9 6.0 6.1 5.1 2.0 19.5 3.5 4.8 17.0 8.1 7.4 3.7 5.2 9.9 4.6 6.5 5.8 4.0 17.9 13.6 3.0 6.7 6.5 7.8 8.4 7.7 4.1 24.9 12.3 51.5 4.4 13.6 15.4 4.5 9.8 6.0 7.8 17.4 4.5 17.7 3.5 3.4 12.5 8.4 14.4 18.8 41.3 2.4 25.2 12.2 2.5 6.0 6.8 2.3 8.3 27.8 27.5 20.7 3.1 11.4 11.0 0.3 1.3 0.2 0.6 1.0 0.2 1.3 0.7 0.4 0.7 2.2 0.9 0.8 1.0 0.8 1.0 4.7 0.1 0.5 11.0 12.7 2.9 16.6 14.4 6.1 4.4 5.3 5.3 5.3 6.5 11.3 1.7 0.0 10.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 5.2 0.0 0.0 1.3 0.0 0.0 4.7 3.0 0.0 0.0 1.4 0.0 5.0 8.9 0.5 0.0 0.0 0.0 4.6 1.2 1.3 0.0 8.8 0.0 9.6 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 19.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 1.9 4.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.8 1.1 9.7 0.0 0.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.5;intestine: 136.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 325.6;Paneth cells: 221.6;Proximal enterocytes: 288.7;Respiratory ciliated cells: 133.9;Undifferentiated cells: 122.2;Urothelial cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.0;naive CD4 T-cell: 3.6;neutrophil: 11.7" "Group enriched" "Detected in many" 14 "granulocytes: 11.7;T-cells: 3.6" "Group enriched" "Detected in some" 5 "OE19: 333.1;RT4: 133.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" 0.7 0.6 1.5 8.3 1.6 1.1 13.2 1.9 1.8 14.9 7.6 95.1 136.4 1.1 13.6 66.5 21.7 24.1 0.1 2.1 2.0 20.6 24.7 6.0 0.9 1.5 2.8 0.2 1.2 12.4 4.2 1.4 1.5 3.6 94.6 0.4 15.4 8.2 0.3 25.4 127.4 2.8 0.9 0.8 24.3 0.3 2.0 0.4 6.5 0.0 15.0 30.8 27.3 1.4 0.1 0.1 0.1 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 39.1 16.8 0.2 7.0 0.0 0.2 22.3 0.0 0.0 0.0 0.1 0.5 0.3 2.1 40.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.2 0.1 0.0 13.3 0.2 1.5 0.2 333.1 49.2 0.3 0.1 2.6 21.0 133.1 4.1 0.6 0.2 10.8 0.1 0.1 37.1 0.2 0.3 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.1 0.3 0.1 1.2 0.5 0.1 0.2 0.1 0.2 0.2 3.0 0.8 0.0 0.4 3.6 0.6 11.7 0.5 0.1 0.3 0.5 0.9 1.5 1.6 1.9 1.8 2.1 2.0 1.5 2.8 1.5 0.9 2.0 1.4 0.1 19.2 12.5 0.3 1.1 3.3 16.4 29.1 0.0 0.1 6.7 2.5 0.8 18.6 68.8 46.0 0.0 3.8 0.0 325.6 13.7 26.9 0.4 27.7 2.9 1.0 55.4 0.0 0.8 8.6 0.8 0.8 17.9 29.5 2.5 0.3 0.4 8.4 0.5 0.0 0.4 49.3 20.3 0.6 0.4 0.3 0.3 2.9 3.6 2.8 0.1 0.1 0.0 0.0 0.3 50.2 221.6 0.0 0.0 23.8 288.7 1.4 133.9 0.2 0.0 0.7 3.6 0.1 0.2 4.4 20.9 0.4 1.8 0.1 122.2 162.0 TMEM63A KIAA0792 ENSG00000196187 "Transmembrane protein 63A" O94886 1 225845536-225882380 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 365.5;salivary gland: 121.1" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 112.2;SK-BR-3: 119.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066504, HPA066936, HPA068918" Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Centriolar satellite" "HPA066504: AB_2685680, HPA066936: AB_2685751, HPA068918: AB_2686057" "unprognostic (5.31e-2)" "unprognostic (3.46e-2)" "unprognostic (2.14e-2)" "prognostic favorable (8.79e-4)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.92e-2)" 24.5 17.9 58.1 27.0 167.3 42.7 29.1 132.2 120.4 35.9 24.6 33.8 26.3 25.7 22.7 15.2 28.2 27.3 20.9 71.6 94.9 33.3 40.2 31.2 35.6 199.1 127.1 28.4 56.7 17.8 11.8 24.2 191.7 57.6 37.0 3.6 121.1 37.3 16.5 21.5 34.5 18.1 95.7 31.6 47.7 5.3 135.3 27.8 19.0 13.7 27.0 26.4 23.2 365.5 27.6 8.3 7.0 20.2 54.1 18.7 47.7 20.6 22.2 22.5 22.6 29.7 20.0 7.7 37.1 25.2 13.3 41.4 7.5 12.5 10.3 25.8 13.4 33.4 21.0 18.0 12.6 12.5 84.1 19.5 7.8 13.5 8.1 31.1 14.8 17.0 28.2 6.3 18.0 17.4 11.2 12.7 37.8 87.5 13.2 11.1 21.3 112.2 34.1 71.8 0.6 3.7 15.2 119.3 14.5 16.0 27.7 11.9 17.8 12.9 8.9 12.1 18.9 2.5 10.4 2.0 11.9 7.0 24.3 6.3 3.9 3.6 10.3 3.1 11.4 5.8 13.1 9.8 2.9 5.5 11.4 6.9 5.5 10.2 5.3 11.5 19.8 6.9 58.1 167.3 132.2 120.4 71.6 94.9 199.1 127.1 191.7 95.7 135.3 365.5 11.0 6.4 9.2 45.7 23.3 3.3 24.9 5.7 2.2 0.8 30.0 16.8 6.5 34.3 14.0 20.2 2.1 38.7 37.0 34.7 1.9 36.3 9.1 43.1 10.6 8.6 19.2 6.3 1.0 25.5 6.6 8.9 48.9 49.8 17.2 44.8 10.8 22.2 16.7 0.0 1.7 35.0 24.4 11.7 5.3 13.5 18.3 14.2 3.6 26.2 10.4 12.9 40.2 5.5 323.2 18.4 29.0 13.2 9.1 41.6 13.0 14.8 23.1 1.8 26.3 8.8 10.8 0.6 5.3 4.2 4.1 22.4 23.3 7.2 57.6 35.1 TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 24.1;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2;SK-BR-3: 26.7;T-47d: 28.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" 2.1 2.8 5.5 1.5 6.3 2.9 4.5 6.2 7.5 34.5 5.1 2.4 2.6 2.4 2.6 132.4 2.5 1.8 1.8 5.2 5.7 2.4 3.6 1.9 2.9 6.2 6.2 2.4 2.1 6.0 3.7 1.6 6.0 28.4 1.3 1.7 23.5 2.6 2.9 89.9 2.7 1.2 5.8 3.8 2.9 2.0 6.1 3.6 2.2 0.7 10.9 6.9 59.4 7.8 12.5 7.2 2.4 4.7 1.8 1.8 5.9 3.5 1.4 6.2 2.4 8.5 3.4 2.2 7.6 0.9 2.2 10.8 2.8 5.1 2.7 8.3 3.9 2.3 3.3 2.5 3.3 2.6 3.3 1.7 30.2 4.6 4.7 4.4 1.4 8.2 10.5 14.8 2.9 14.1 7.3 4.0 3.6 9.0 5.7 8.5 2.3 5.0 1.3 3.0 4.3 4.7 4.3 26.7 7.0 2.9 28.3 7.4 3.4 11.5 3.8 4.2 9.5 11.3 13.0 5.2 8.0 6.0 8.8 0.0 2.0 3.0 1.7 0.7 1.8 1.7 1.5 1.8 1.6 2.2 2.0 2.4 3.7 1.7 1.3 2.0 2.1 1.7 5.5 6.3 6.2 7.5 5.2 5.7 6.2 6.2 6.0 5.8 6.1 7.8 1.8 3.2 1.5 8.8 3.9 13.3 1.4 24.1 9.1 3.0 10.0 6.5 1.2 2.8 14.3 1.8 2.1 7.7 3.6 2.4 1.9 2.5 0.1 3.7 2.4 2.0 3.0 0.8 1.8 3.3 1.8 2.1 1.5 6.7 0.0 3.1 2.2 2.4 3.4 8.4 2.2 2.9 10.2 2.5 1.8 0.3 1.5 1.4 5.4 3.7 4.4 1.5 1.0 2.5 5.8 4.5 2.1 0.7 1.6 10.7 4.3 1.6 4.2 2.2 0.0 1.0 1.9 1.3 2.1 59.9 33.1 7.4 3.2 2.9 3.1 6.4 TMEM88 "FLJ20025, MGC71744" ENSG00000167874 "Transmembrane protein 88" Q6PEY1 17 7855066-7856099 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.5" "Group enriched" "Detected in many" 7 "Adipocytes: 177.3;Endothelial cells: 142.1;Hepatic stellate cells: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Group enriched" "Detected in many" 6 "AN3-CA: 65.2;HHSteC: 42.3;HUVEC TERT2: 51.4;NTERA-2: 26.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052991 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052991: AB_2682006" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (3.44e-2)" "unprognostic (3.03e-1)" "unprognostic (6.49e-2)" "prognostic favorable (4.43e-6)" "unprognostic (1.98e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-3)" "unprognostic (9.04e-2)" "unprognostic (1.09e-2)" "unprognostic (2.68e-3)" "unprognostic (1.71e-1)" "unprognostic (7.56e-2)" "unprognostic (2.72e-1)" 63.2 22.3 11.2 7.9 11.0 6.9 29.5 12.4 24.4 20.0 14.3 18.1 5.7 24.1 3.6 6.4 26.4 12.7 98.5 11.3 11.6 37.7 5.9 14.1 3.6 12.6 11.6 8.5 10.8 7.4 21.4 23.7 12.0 19.3 2.7 2.4 9.3 6.3 35.4 3.8 15.4 10.1 11.0 15.9 18.2 4.9 12.9 2.5 39.6 36.8 0.8 19.1 14.0 10.9 0.2 0.8 8.1 65.2 0.0 0.3 3.9 0.4 0.2 0.1 0.2 1.9 0.3 0.4 0.3 0.7 0.4 0.5 0.6 0.4 0.1 0.0 0.1 0.5 1.2 1.1 42.3 0.6 2.6 1.0 1.8 1.2 0.3 0.6 51.4 0.9 1.2 0.1 0.8 5.0 0.5 1.2 26.5 0.3 0.0 0.3 0.2 0.1 0.6 1.6 0.7 3.7 0.5 0.8 2.0 2.2 1.4 0.2 5.2 0.4 1.6 2.2 0.5 0.2 0.1 0.4 0.2 0.4 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 11.2 11.0 12.4 24.4 11.3 11.6 12.6 11.6 12.0 11.0 12.9 10.9 177.3 6.4 2.2 2.0 6.2 4.1 4.0 1.4 2.2 4.7 7.9 5.2 5.9 0.0 2.4 1.8 4.2 3.1 3.1 2.0 0.0 2.2 3.0 3.1 2.0 142.1 6.6 0.0 0.6 2.2 1.0 19.2 4.6 6.7 4.5 1.8 109.9 2.4 2.6 3.3 0.9 2.5 0.0 7.3 9.3 8.6 0.9 9.9 0.0 5.6 0.2 0.6 0.0 0.0 0.1 4.0 5.7 0.0 1.0 6.5 2.4 0.6 1.5 1.4 0.0 11.3 6.5 1.7 1.8 2.7 3.1 5.2 2.5 0.8 1.5 3.2 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMOD1 "D9S57E, ETMOD, TMOD" ENSG00000136842 "Tropomodulin 1" P28289 9 97501180-97601743 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 250.0;tongue: 255.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.0;Erythroid cells: 138.9;Horizontal cells: 102.6" "Group enriched" "Detected in many" 4 "glioma: 21.6;ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 38.0;HDLM-2: 155.7;K-562: 53.3;SH-SY5Y: 157.4" "Low region specificity" "Detected in all" HPA051202 Enhanced NA NA 9400 "Cluster 40: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA051202: AB_2681387" "unprognostic (8.54e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-3)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "unprognostic (2.62e-3)" "unprognostic (2.82e-1)" "unprognostic (3.09e-1)" "unprognostic (2.09e-1)" "unprognostic (2.91e-1)" "unprognostic (1.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.42e-1)" "unprognostic (2.02e-1)" "unprognostic (4.88e-5)" 18.8 65.1 16.8 4.5 19.9 24.2 15.8 25.0 22.0 46.4 16.3 34.8 4.2 54.3 5.6 17.4 27.4 7.4 144.2 18.0 25.7 9.2 28.5 15.5 2.6 20.1 12.1 51.3 23.0 13.9 31.6 2.6 17.3 17.1 6.3 9.2 10.4 9.1 250.0 7.5 12.2 36.3 17.8 3.5 18.4 2.8 12.6 1.0 21.9 255.8 2.4 38.3 25.4 22.6 5.4 1.4 0.0 0.7 6.3 0.6 1.9 1.0 9.1 0.1 0.2 1.2 1.6 0.1 38.0 0.1 8.5 0.4 1.6 0.0 0.0 155.7 5.6 7.4 8.8 0.6 0.2 0.1 12.5 0.5 0.0 0.4 0.0 0.1 0.7 0.2 53.3 0.1 0.1 2.3 0.0 1.0 2.0 1.5 0.6 0.0 5.1 0.1 0.0 1.1 0.6 157.4 4.8 0.1 2.7 2.1 2.0 7.7 0.8 0.0 5.7 4.3 1.1 19.1 4.1 0.2 7.0 5.1 8.4 0.8 0.3 0.5 1.2 0.3 1.1 1.2 1.0 0.7 0.5 2.0 0.6 0.7 0.0 0.7 0.4 0.1 2.2 1.1 16.8 19.9 25.0 22.0 18.0 25.7 20.1 12.1 17.3 17.8 12.6 22.6 4.7 6.4 4.2 2.3 1.9 2.3 1.0 0.0 0.0 1.1 1.6 1.3 60.0 4.3 0.0 0.0 6.2 0.2 1.1 0.0 0.0 0.3 0.8 10.2 14.5 13.0 3.0 138.9 27.6 6.5 0.4 12.8 4.6 27.7 10.8 0.1 27.5 20.2 0.9 102.6 19.3 0.4 0.0 13.7 4.2 0.6 10.2 6.5 17.8 6.5 0.1 2.2 0.0 31.2 5.9 4.7 0.0 6.8 0.4 2.1 0.0 0.2 0.0 1.3 19.7 8.8 23.9 2.6 6.8 0.2 1.0 0.1 3.2 0.1 0.1 0.9 TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" 12.2 7.4 4.8 13.6 4.9 9.7 9.4 4.2 5.3 11.4 6.7 15.4 15.5 9.9 10.3 43.4 13.2 11.8 6.9 4.2 3.7 13.5 13.7 21.7 12.8 5.0 5.2 6.9 8.0 7.3 3.4 21.9 4.9 7.5 15.4 3.6 12.8 9.8 3.4 15.0 16.0 9.6 4.9 13.7 16.9 3.4 5.8 12.6 9.6 6.4 19.5 16.4 18.7 5.0 59.4 56.0 22.3 5.8 21.6 35.9 25.8 26.1 35.5 26.7 23.8 21.8 42.4 13.9 21.7 28.0 18.9 82.3 20.7 58.5 33.9 23.8 9.1 20.6 62.6 17.9 24.0 26.6 22.1 24.2 55.7 21.5 66.2 32.9 47.7 20.0 22.3 20.6 32.6 43.9 17.8 17.7 12.4 36.3 10.3 21.0 26.7 37.8 43.5 41.5 5.4 14.6 43.5 28.9 15.6 29.7 19.7 21.0 53.8 33.9 22.6 27.8 31.3 12.5 39.5 15.6 21.7 48.0 20.4 47.6 27.9 41.4 22.7 34.7 20.2 20.4 19.8 20.3 20.6 23.8 16.7 15.7 45.5 18.8 39.3 29.0 26.0 16.7 4.8 4.9 4.2 5.3 4.2 3.7 5.0 5.2 4.9 4.9 5.8 5.0 147.9 397.4 68.2 23.8 43.5 106.9 91.4 66.3 70.6 8.3 38.8 27.3 45.8 30.0 112.7 42.3 14.6 56.1 63.3 117.4 41.1 85.8 38.9 67.5 87.6 131.6 18.6 50.9 29.4 71.6 66.3 84.1 71.9 91.3 143.0 28.8 101.4 52.9 53.9 15.2 25.5 52.0 36.7 51.7 74.1 99.3 45.1 88.4 32.0 33.7 67.5 19.2 60.8 17.1 17.1 152.6 79.0 44.4 44.1 160.3 65.5 56.5 82.2 12.6 13.1 35.2 58.0 14.5 13.9 137.0 132.1 51.3 74.3 57.4 59.9 215.9 TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 86.1;lymphoid tissue: 28.4;vagina: 41.7" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 50.7" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA078316: " "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 19.9 0.0 0.0 0.0 0.0 0.0 86.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.4 12.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.0 28.4 0.3 41.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.3 0.2 0.3 0.9 0.4 1.1 0.1 0.3 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.5 1.2 0.6 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.1 0.2 50.7 0.0 0.0 0.0 0.0 0.0 7.2 TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "cervix: 51.6;esophagus: 71.8;lymphoid tissue: 34.4;salivary gland: 21.0;vagina: 76.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 24.4;Club cells: 13.8;Inhibitory neurons: 3.9;Oligodendrocyte precursor cells: 5.0;Urothelial cells: 12.0" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA077704: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.3 2.6 51.6 1.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 2.6 2.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 21.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.9 0.2 0.0 0.0 34.4 0.6 76.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 2.6 1.1 1.1 2.6 2.0 2.7 0.7 0.9 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.1 24.4 0.6 0.0 0.0 0.0 0.3 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 5.0 1.5 0.5 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 12.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMPRSS4 "MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.7;intestine: 43.5;urinary bladder: 74.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.7;Club cells: 103.5;Distal enterocytes: 187.9;Squamous epithelial cells: 119.2;Urothelial cells: 258.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in single" 7 "basophil: 2.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.1" "Group enriched" "Detected in some" 5 "CAPAN-2: 103.7;HaCaT: 39.2;OE19: 141.6;RPTEC TERT1: 70.6;RT4: 95.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" 0.2 0.0 0.1 6.1 0.1 0.8 0.3 1.8 0.3 16.6 0.3 43.5 25.4 2.1 3.2 108.7 1.0 14.3 0.2 0.1 0.0 21.1 0.2 1.4 0.2 0.1 0.0 0.1 0.3 0.0 0.2 0.1 0.2 7.8 42.9 0.4 6.5 0.2 0.2 4.1 22.4 1.5 0.0 0.2 31.4 1.1 0.2 1.1 0.2 0.1 14.9 74.6 16.7 0.3 18.5 0.1 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.7 103.7 0.1 3.5 0.0 0.1 39.2 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.4 0.3 0.0 1.3 0.3 4.5 0.1 141.6 0.0 0.1 0.1 0.2 70.6 95.9 0.1 0.1 0.0 8.4 0.1 0.2 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.8 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 1.7 0.0 0.4 1.1 35.2 101.7 38.1 0.0 0.0 0.0 0.7 0.0 103.5 11.0 0.0 0.2 0.0 187.9 0.0 1.5 3.0 45.3 4.6 0.8 4.2 0.0 0.2 7.3 3.0 0.5 53.5 66.4 5.7 0.0 0.0 0.1 0.2 0.0 0.2 55.3 34.6 0.3 0.3 2.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 52.6 67.5 0.0 2.7 17.5 55.2 2.4 69.4 0.0 0.0 0.0 4.7 0.0 0.1 119.2 6.3 0.3 0.5 0.0 71.2 258.6 TMSB15A "TMSL8, TMSNB" ENSG00000158164 "Thymosin beta 15A" P0CG34 X 102513682-102516739 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.0;prostate: 15.8" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 12.8;Granulosa cells: 25.9;Prostatic glandular cells: 13.8;Smooth muscle cells: 13.5;Spermatogonia: 19.8" "Group enriched" "Detected in many" 4 "glioma: 20.1;prostate cancer: 56.4;testis cancer: 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 571.5;HAP1: 110.2;MOLT-4: 113.4;NTERA-2: 148.0;RH-30: 259.9;SH-SY5Y: 148.1" "Low region specificity" "Detected in all" NA NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.33e-3)" "unprognostic (3.09e-2)" "unprognostic (1.70e-2)" "unprognostic (5.82e-3)" "unprognostic (1.34e-1)" "unprognostic (4.03e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-2)" "unprognostic (1.59e-2)" "unprognostic (1.45e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-3)" "unprognostic (2.96e-4)" "unprognostic (2.14e-1)" "unprognostic (7.83e-2)" "unprognostic (2.07e-1)" 1.0 1.0 1.1 1.1 1.2 1.0 5.1 1.7 2.1 5.1 1.4 0.9 0.4 5.0 0.7 0.3 1.9 1.2 1.9 1.2 1.1 2.4 0.1 7.1 4.0 1.3 1.0 4.7 0.9 0.8 0.8 0.5 1.3 15.8 1.1 1.4 3.9 1.2 0.3 0.5 0.6 2.3 1.1 0.4 0.5 4.8 1.2 13.0 5.9 0.3 2.8 0.7 2.3 1.1 0.1 0.0 571.5 107.7 2.4 0.3 0.2 12.4 0.7 1.7 4.8 0.0 0.7 0.0 1.3 2.1 28.5 0.0 110.2 0.7 1.2 0.0 5.6 10.3 1.7 0.3 0.3 0.2 10.1 1.4 0.0 1.1 0.0 14.3 6.7 5.5 1.0 0.0 41.2 0.1 113.4 0.2 148.0 0.0 1.4 0.2 259.9 0.0 11.7 0.2 98.1 148.1 14.0 0.9 0.3 22.0 1.4 3.2 2.4 0.3 62.6 1.4 10.5 11.8 2.1 0.0 6.7 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 1.1 1.2 1.7 2.1 1.2 1.1 1.3 1.0 1.3 1.1 1.2 1.1 1.4 0.0 0.0 0.0 0.0 0.8 0.9 0.1 1.8 0.3 7.3 12.8 0.1 0.0 0.0 0.0 0.0 0.5 0.5 0.5 0.0 0.5 0.3 0.5 5.6 1.2 0.0 0.8 0.0 0.0 0.5 4.6 0.0 1.2 0.0 25.9 2.5 0.0 0.5 0.0 0.0 0.6 0.0 0.6 0.5 0.1 0.3 0.1 1.8 0.0 0.0 0.7 1.0 0.5 0.0 0.0 0.1 2.6 0.3 13.8 0.1 0.4 0.0 0.1 6.6 1.2 13.5 3.4 19.8 1.8 0.0 0.3 0.7 0.9 0.9 1.0 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 10.3;Inhibitory neurons: 14.4;Langerhans cells: 10.8;Smooth muscle cells: 9.3;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;ASC TERT1: 87.8;HUVEC TERT2: 78.7;LHCN-M2: 74.5;TIME: 105.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" 9.4 3.8 9.2 7.1 8.3 0.8 5.7 3.5 8.2 13.7 4.3 8.6 1.6 86.9 6.0 20.4 45.6 6.2 6.3 15.3 6.6 2.7 2.4 15.5 3.9 5.5 8.5 15.9 2.4 0.8 3.0 2.0 4.8 6.8 8.6 0.3 3.9 5.4 4.7 23.1 7.9 84.8 4.3 19.9 5.8 4.4 6.6 0.9 5.4 3.5 3.2 18.6 15.1 5.6 0.1 0.4 0.1 0.2 35.0 87.8 0.4 0.3 0.1 1.0 1.6 0.1 1.0 0.1 1.5 5.0 11.2 0.1 1.2 0.8 0.4 0.1 0.7 0.0 2.4 5.9 9.1 0.3 1.9 32.5 7.1 6.7 26.8 5.8 78.7 0.1 0.1 0.1 74.5 0.9 0.0 0.6 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.1 0.1 0.1 0.9 0.5 0.6 105.5 8.0 0.5 26.5 2.3 0.4 0.0 0.1 16.7 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.3 0.2 0.2 0.0 0.0 9.2 8.3 3.5 8.2 15.3 6.6 5.5 8.5 4.8 4.3 6.6 5.6 1.2 0.0 0.5 4.6 0.0 3.3 1.1 0.4 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 2.3 1.7 3.9 10.3 0.0 4.5 0.4 0.0 5.8 0.0 0.1 0.0 7.1 1.8 0.3 2.9 0.0 14.4 3.3 2.0 2.9 10.8 0.7 9.0 3.5 1.8 1.0 0.6 0.1 0.0 1.0 2.6 0.1 1.5 5.3 0.1 0.4 0.0 0.1 1.3 0.2 6.6 1.6 9.3 23.7 0.8 0.3 8.4 0.0 0.1 0.1 1.5 0.5 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 148.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 179.9;Prostatic glandular cells: 180.8;Syncytiotrophoblasts: 178.7;Urothelial cells: 387.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.2" "Lineage enriched" "Detected in single" 303 "dendritic cells: 69.2" "Cell line enhanced" "Detected in many" "OE19: 208.0;RT4: 523.8;SuSa: 213.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" 55.7 6.6 17.6 17.7 31.0 13.4 13.4 48.9 31.4 17.5 1.1 38.1 12.3 17.1 2.5 41.3 16.4 35.7 9.8 21.8 27.4 49.6 8.9 16.9 17.2 76.8 43.8 6.5 20.0 58.8 6.5 33.2 56.9 13.7 34.8 4.1 25.6 4.0 6.0 4.0 19.2 15.7 43.7 14.9 60.8 8.1 49.0 26.8 4.0 14.1 32.9 148.1 17.1 100.1 156.6 50.0 47.7 15.3 127.4 37.5 53.9 17.9 34.9 5.5 2.1 86.7 107.7 11.6 70.3 13.1 101.8 92.2 7.2 66.1 3.1 0.2 15.1 0.1 6.4 88.2 74.6 2.5 0.6 67.1 77.2 3.3 58.1 4.2 25.8 10.1 3.8 0.1 1.9 30.8 13.9 1.4 37.5 208.0 50.8 29.1 14.7 17.1 90.8 523.8 34.1 7.5 15.6 14.4 12.9 213.0 11.1 11.0 5.2 14.1 12.9 0.5 16.5 0.1 0.2 16.1 23.1 11.1 40.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.1 0.1 0.1 69.2 0.0 0.6 17.6 31.0 48.9 31.4 21.8 27.4 76.8 43.8 56.9 43.7 49.0 100.1 5.5 0.0 9.8 1.6 3.1 23.7 179.9 140.5 64.9 1.1 8.0 10.8 10.2 35.8 59.9 1.8 0.0 31.0 77.3 100.7 15.6 86.8 55.0 12.0 17.3 8.6 12.0 3.0 46.6 29.6 21.4 32.9 80.5 13.8 19.7 2.1 1.1 0.3 22.4 0.0 29.6 42.9 107.8 53.6 12.5 40.3 2.8 22.6 12.4 13.1 0.6 5.4 0.0 53.3 44.7 89.1 54.5 1.2 2.0 180.8 14.7 51.3 54.7 1.4 78.9 21.5 24.2 1.0 3.7 40.4 9.9 178.7 2.8 13.1 19.9 387.3 TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Cardiomyocytes: 339.0;Leydig cells: 169.6;Peritubular cells: 504.0;Sertoli cells: 368.1;Smooth muscle cells: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.1;ASC TERT1: 74.1;fHDF/TERT166: 66.6;REH: 75.4;TIME: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "CAB018774: AB_2207032, HPA036089: AB_10796111, HPA036090: AB_10794322" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.13e-2)" "unprognostic (5.46e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-3)" "unprognostic (7.34e-2)" "unprognostic (2.55e-2)" "unprognostic (1.28e-3)" "unprognostic (5.57e-2)" "unprognostic (9.74e-2)" "unprognostic (4.71e-3)" "unprognostic (5.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.49e-2)" "prognostic unfavorable (5.19e-4)" 248.2 60.3 51.6 42.9 98.0 42.3 100.9 71.7 45.5 99.5 45.1 373.4 23.4 253.7 44.3 117.8 136.2 80.4 170.4 34.0 53.4 74.6 39.6 117.2 11.5 82.3 79.2 110.4 55.2 33.2 15.4 54.5 106.4 126.1 41.7 7.7 52.9 225.0 171.6 47.8 78.9 178.0 72.2 70.1 115.2 23.5 80.9 21.5 65.8 207.2 7.5 228.4 82.6 82.9 0.3 0.4 8.9 0.1 135.1 74.1 0.8 22.9 7.8 1.3 0.9 10.0 0.1 0.0 13.1 66.6 1.5 1.7 1.4 1.3 0.7 9.4 0.8 19.8 5.7 2.6 9.8 0.1 2.3 35.2 0.0 24.4 0.2 43.6 32.2 0.1 0.6 2.6 18.8 4.4 0.1 1.4 0.9 0.2 0.4 75.4 16.8 1.0 4.8 0.2 2.1 10.1 3.9 9.7 2.0 6.1 3.1 8.5 63.2 16.6 29.5 17.5 4.9 1.1 0.1 0.1 9.8 2.7 1.2 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.8 51.6 98.0 71.7 45.5 34.0 53.4 82.3 79.2 106.4 72.2 80.9 82.9 93.3 173.1 85.9 29.7 1.1 16.2 48.6 29.5 42.1 4.8 7.2 21.2 339.0 38.6 27.5 14.7 0.0 8.7 0.5 0.1 7.9 36.1 2.2 3.0 29.5 76.6 0.0 143.1 3.9 19.1 1.5 52.4 1.1 3.8 30.4 8.8 71.7 38.5 13.0 42.1 5.3 0.0 6.1 15.3 19.3 11.9 169.6 16.7 10.6 32.8 1.3 14.1 0.0 15.6 52.0 17.0 0.0 504.0 0.4 12.1 0.0 26.1 22.3 1.3 368.1 29.7 183.5 1.1 1.9 5.7 11.8 1.9 4.1 20.7 0.2 17.3 TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Apoptosis Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 205.0;vagina: 74.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 133.4;Basal prostatic cells: 117.7;Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 77.4;Suprabasal keratinocytes: 65.5;Urothelial cells: 50.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 77.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 136.2;HBEC3-KT: 613.4;hTCEpi: 435.3;hTERT-HME1: 138.8;OE19: 125.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.16e-2)" "unprognostic (9.83e-2)" "unprognostic (1.01e-1)" "unprognostic (3.40e-2)" "unprognostic (3.68e-4)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.89e-1)" "unprognostic (8.02e-3)" "unprognostic (2.01e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (3.72e-1)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" 0.9 0.1 0.0 1.1 0.0 0.1 16.5 0.0 0.0 28.6 0.1 3.2 0.8 0.7 3.5 46.1 0.9 0.3 0.1 0.0 0.0 1.0 0.1 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.9 9.7 0.0 35.6 5.9 0.0 58.8 19.6 0.2 205.0 0.8 0.1 0.0 0.0 1.8 0.0 0.0 1.4 14.3 0.0 6.9 14.8 74.7 0.2 7.7 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 18.6 0.1 3.9 0.0 0.0 136.2 0.0 613.4 0.0 0.0 0.0 0.0 57.5 9.3 0.0 0.0 0.4 0.0 435.3 0.0 138.8 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.0 125.9 70.2 0.0 0.0 0.0 0.0 32.3 0.0 0.0 79.4 14.4 0.0 0.7 16.0 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 133.4 117.7 39.8 287.4 0.0 1.6 25.5 0.9 0.0 18.2 0.0 0.0 4.7 0.5 7.5 1.9 0.2 0.0 4.6 0.7 1.3 0.0 0.0 0.1 0.2 0.5 1.0 2.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 3.5 2.0 0.0 8.8 0.0 0.0 1.1 5.4 0.0 0.6 0.0 0.0 0.0 0.1 25.2 0.3 0.0 0.0 18.9 0.1 0.0 7.3 0.0 0.0 0.1 1.6 0.0 0.0 77.4 65.5 4.4 2.1 0.0 2.6 50.2 TP53INP2 "C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH" ENSG00000078804 "Tumor protein p53 inducible nuclear protein 2" Q8IXH6 20 34704339-34713439 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 517.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.5;Early spermatids: 208.6;Late spermatids: 353.7;Paneth cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.7" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 219.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.33e-2)" "unprognostic (2.57e-3)" "unprognostic (1.26e-1)" "unprognostic (3.08e-2)" "unprognostic (2.07e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (1.52e-2)" "unprognostic (2.57e-2)" "prognostic favorable (1.26e-8)" "unprognostic (8.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (6.17e-2)" 19.7 28.0 315.7 11.1 439.0 89.7 13.8 343.9 403.1 19.6 159.7 42.2 19.9 26.4 15.7 64.8 19.3 23.8 85.5 233.8 348.8 31.8 45.6 19.6 5.6 517.3 444.7 15.5 16.6 35.1 22.0 10.5 464.6 36.9 38.4 45.9 27.6 31.2 53.1 12.3 23.5 34.7 418.6 6.6 24.4 39.9 376.8 2.9 31.6 94.0 17.2 33.0 23.8 485.7 2.5 3.0 9.8 12.6 22.1 18.1 4.2 9.8 30.9 12.8 10.6 17.3 1.2 7.7 6.6 19.6 25.1 1.9 20.8 4.7 14.0 2.3 2.6 14.0 8.2 16.9 28.6 2.2 10.9 52.3 7.0 10.1 1.4 16.0 20.2 6.9 5.8 24.8 14.5 3.4 1.6 4.8 1.3 2.1 7.4 7.4 6.4 12.4 16.1 8.8 21.4 24.1 8.7 219.0 15.2 11.6 15.8 10.3 15.3 35.0 12.0 4.6 4.1 9.8 12.5 6.2 22.2 31.2 12.5 0.5 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 315.7 439.0 343.9 403.1 233.8 348.8 517.3 444.7 464.6 418.6 376.8 485.7 9.5 3.2 10.6 5.5 8.1 3.7 17.0 11.7 5.7 20.4 17.4 12.3 75.4 15.7 16.7 3.7 52.1 1.7 12.8 143.5 5.9 16.5 208.6 19.6 10.1 10.4 52.4 0.4 4.3 23.9 1.1 9.6 46.9 24.2 7.0 7.5 11.0 28.7 5.3 32.0 6.1 59.5 32.6 10.2 3.6 353.7 7.5 15.5 5.4 2.8 2.6 10.9 0.0 1.0 17.7 24.3 116.1 13.2 7.4 15.3 34.0 8.9 25.1 55.8 19.7 35.9 27.4 4.0 2.7 4.5 3.0 28.5 8.4 9.1 23.9 24.4 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TP73 P73 ENSG00000078900 "Tumor protein p73" O15350 1 3652516-3736201 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.0;fallopian tube: 6.7;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 13.0;Basal squamous epithelial cells: 16.5;Early spermatids: 21.8;Endometrial ciliated cells: 31.0;Late spermatids: 15.7;Respiratory ciliated cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 15.0;RH-30: 11.6;SCLC-21H: 18.0;U-698: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002514, CAB003022, HPA027314, HPA044516" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "CAB002514: AB_563940, CAB003022: , HPA027314: AB_2672215, HPA044516: AB_2678971" "unprognostic (5.71e-3)" "prognostic favorable (2.98e-4)" "unprognostic (2.71e-1)" "prognostic favorable (1.82e-4)" "unprognostic (5.58e-2)" "prognostic favorable (9.50e-4)" "unprognostic (5.25e-2)" "unprognostic (2.18e-1)" "unprognostic (4.27e-1)" "unprognostic (1.99e-1)" "unprognostic (5.33e-2)" "unprognostic (3.99e-1)" "unprognostic (1.26e-7)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (7.33e-2)" "unprognostic (1.65e-1)" 0.0 0.0 0.7 0.7 0.5 0.5 0.8 4.2 0.5 1.4 8.0 0.2 0.0 0.1 0.1 3.7 6.7 0.0 0.1 0.8 0.7 0.1 0.2 0.9 1.0 2.4 2.9 0.1 0.8 0.1 0.3 0.0 1.4 2.6 0.1 0.2 2.9 0.3 0.2 6.6 0.2 0.0 1.4 0.7 0.3 0.7 0.7 1.6 0.2 0.0 1.4 0.1 2.9 1.0 2.6 0.1 0.3 7.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.9 4.0 2.6 2.0 0.0 0.9 4.3 2.7 0.9 0.0 0.8 8.7 0.2 3.9 2.6 0.0 0.0 2.9 0.0 1.7 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.8 1.9 15.0 2.0 0.5 0.0 0.1 0.0 11.6 0.1 0.3 3.8 18.0 8.4 0.4 0.0 0.8 0.0 10.9 9.2 0.0 2.9 7.5 0.0 5.8 3.3 0.7 18.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 4.2 0.5 0.8 0.7 2.4 2.9 1.4 1.4 0.7 1.0 0.0 0.0 1.5 0.0 1.2 3.1 3.8 13.0 16.5 0.5 0.2 2.5 1.5 0.0 7.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 21.8 31.0 0.3 0.3 2.4 3.2 0.1 0.2 0.4 0.4 0.0 0.7 0.0 0.1 0.4 0.2 0.3 0.0 0.1 0.5 2.0 0.0 1.3 15.7 0.6 0.1 1.8 0.0 0.0 0.2 0.0 2.5 0.1 0.2 0.0 0.0 6.8 0.2 0.0 0.1 35.8 0.1 0.0 0.0 2.6 0.1 0.4 1.6 2.3 0.3 0.4 0.1 0.3 0.2 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10621.0;skeletal muscle: 12678.0;tongue: 5183.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 13012.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.7" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.7;monocytes: 19.2" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 3141.3;SuSa: 3810.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" 372.0 103.6 49.8 232.9 53.2 21.6 348.8 52.4 53.9 577.4 59.3 2947.3 289.6 1566.9 250.5 639.0 823.8 288.0 10621.0 53.3 42.2 215.5 94.8 247.1 48.1 42.5 44.3 320.3 383.4 37.5 70.6 206.4 43.7 809.6 523.1 83.9 258.2 1545.5 12678.0 150.7 680.8 1754.9 44.8 134.3 976.5 52.3 50.0 21.1 156.8 5183.6 29.4 1511.0 425.8 42.2 554.5 357.3 418.1 20.9 143.1 89.9 1335.5 1509.1 552.8 905.9 669.2 253.9 107.6 1.7 677.7 1517.1 602.7 295.9 361.8 243.4 597.0 14.5 50.9 81.2 376.3 124.5 403.3 3.8 17.9 125.7 138.0 742.1 198.2 3141.3 243.2 14.7 8.7 20.4 695.3 286.4 25.6 7.1 496.0 129.0 61.1 9.0 146.5 15.8 1308.7 298.8 101.1 71.7 180.9 284.4 65.1 3810.3 204.8 15.3 1095.8 1178.8 572.0 181.6 1094.8 5.9 4.3 7.8 335.9 22.4 842.1 48.7 9.9 4.8 4.0 19.2 3.1 5.5 3.6 4.3 14.1 5.6 4.0 3.6 10.7 1.9 14.3 2.4 6.3 15.6 49.8 53.2 52.4 53.9 53.3 42.2 42.5 44.3 43.7 44.8 50.0 42.2 542.3 57.7 86.3 19.9 12.1 71.9 202.0 344.1 18.2 49.0 450.1 953.1 13012.4 346.0 147.0 318.2 383.7 212.1 20.6 561.3 187.9 2502.6 6.5 147.2 614.4 294.3 267.7 137.0 44.2 1671.1 3094.8 557.1 279.3 211.2 52.0 85.3 175.6 138.1 201.5 52.2 53.2 964.7 183.1 42.5 72.1 27.3 205.0 114.3 81.8 111.5 47.5 47.4 28.8 36.2 6.0 2372.3 623.4 1130.3 8.8 244.3 724.7 361.1 104.2 447.5 1038.7 484.0 1685.9 27.4 82.2 29.4 50.4 103.0 29.0 130.7 385.3 198.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" 140.7 103.2 95.0 233.2 104.1 590.1 97.1 83.3 116.2 94.9 73.3 199.0 163.5 69.6 73.4 287.4 100.6 136.1 318.5 104.8 101.5 81.5 114.4 178.7 287.3 96.6 101.4 45.4 265.9 91.7 19.6 141.1 101.6 122.3 201.5 60.3 101.5 56.0 8905.8 103.0 167.8 111.6 94.6 208.9 152.8 64.8 93.8 203.0 88.8 6106.5 287.2 183.2 29.7 98.2 529.4 332.8 306.1 225.4 262.1 341.1 317.9 439.0 419.1 597.9 437.7 596.1 513.9 414.6 366.9 500.2 206.4 472.1 320.0 468.7 485.8 315.7 171.9 537.6 234.1 311.7 200.9 728.2 627.5 260.0 246.2 515.8 355.1 224.9 929.4 269.0 411.8 429.7 710.0 342.2 582.0 683.1 714.2 775.9 515.9 510.0 233.2 574.9 405.6 387.4 234.4 409.4 360.0 443.7 419.2 303.9 645.0 788.9 758.8 558.8 353.9 497.3 711.1 332.4 623.0 516.2 490.7 514.7 860.0 932.1 743.2 1729.3 547.2 945.6 480.1 395.2 464.0 504.4 792.6 324.5 347.2 442.6 824.3 386.4 1104.4 392.9 551.5 2029.4 95.0 104.1 83.3 116.2 104.8 101.5 96.6 101.4 101.6 94.6 93.8 98.2 346.0 621.8 343.2 17.6 318.6 149.5 227.6 169.5 127.5 84.2 135.4 88.4 85.0 125.8 275.6 97.5 31.3 127.3 475.7 494.5 105.7 292.1 72.3 353.7 191.1 395.7 141.0 189.8 65.7 347.0 331.0 170.4 245.6 474.2 531.3 119.5 200.3 110.6 559.1 304.5 50.5 291.2 93.6 355.6 504.7 182.3 46.6 648.3 152.9 31.9 704.0 54.5 466.5 12.5 30.6 530.4 363.9 29.7 218.2 204.8 220.1 179.8 230.8 62.8 19.7 155.1 128.5 38.6 67.6 223.6 143.3 101.9 422.6 119.2 302.1 324.6 TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 261.6;Kupffer cells: 376.5;Macrophages: 219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 9500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 74.7 145.9 71.0 74.6 81.0 111.7 44.3 80.3 81.4 53.8 120.1 59.1 59.9 74.0 43.1 39.5 47.1 65.1 56.3 70.6 78.4 71.6 92.7 81.5 77.7 85.2 82.6 49.7 36.2 54.2 63.6 94.2 81.0 38.9 59.7 48.5 42.5 57.5 31.4 39.5 73.3 92.0 74.7 135.0 48.4 20.0 83.3 47.4 45.7 39.0 60.9 68.4 42.8 90.4 26.1 48.1 25.9 50.5 309.9 160.1 21.8 50.9 220.7 36.9 62.0 20.1 122.5 37.4 32.6 136.6 220.2 85.8 48.3 68.7 57.9 37.3 27.6 32.2 23.8 54.9 210.9 45.8 182.6 231.8 104.5 45.9 102.6 240.4 158.8 32.9 59.8 124.6 110.4 30.2 16.6 52.4 18.0 61.5 57.1 36.1 21.6 77.0 62.8 38.2 4.5 20.4 52.6 44.6 91.0 76.5 30.8 79.7 188.0 119.7 33.1 101.1 19.8 92.3 95.3 14.0 139.8 101.7 64.5 67.0 167.1 38.2 39.9 171.2 30.0 35.1 31.4 41.0 185.9 37.0 20.1 27.2 27.5 29.1 125.1 93.1 60.3 138.8 71.0 81.0 80.3 81.4 70.6 78.4 85.2 82.6 81.0 74.7 83.3 90.4 32.0 25.6 37.3 31.6 53.0 23.7 28.4 29.8 13.1 24.8 21.1 23.9 41.8 50.1 26.8 16.5 12.5 35.4 71.0 55.2 5.9 42.2 11.8 13.3 30.2 40.7 16.7 37.5 12.5 13.4 45.3 40.3 16.3 24.8 62.2 25.6 75.7 81.0 261.6 15.2 12.4 31.3 26.4 376.5 126.5 11.2 27.1 219.8 90.7 15.9 156.0 37.9 49.4 8.0 21.9 17.4 44.1 26.4 26.4 23.5 99.7 51.6 14.5 23.8 6.6 19.0 20.3 0.8 1.1 27.6 20.0 88.0 42.2 24.6 32.5 26.5 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 130.5" "Cell type enhanced" "Detected in many" "B-cells: 133.8;dendritic cells: 124.7;NK-cells: 407.8;T-cells: 162.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 115.2;JURKAT: 64.2;Karpas-707: 46.2;MOLT-4: 60.9;NB-4: 68.7;THP-1: 64.1;U-266/70: 68.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" 3.6 2.3 1.9 51.6 2.0 31.8 4.1 1.8 4.2 3.5 1.4 8.2 7.4 2.8 2.7 3.4 2.0 10.5 1.7 2.0 2.0 4.2 5.7 10.8 99.7 3.0 2.6 2.1 0.9 0.7 0.8 2.0 3.0 3.4 10.4 0.3 5.6 2.8 1.1 2.4 30.6 3.8 2.3 60.1 13.4 3.8 3.0 130.5 3.0 1.9 90.5 11.7 2.2 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 115.2 0.0 11.0 0.0 0.0 0.2 17.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.1 46.2 0.0 0.0 60.9 68.7 0.2 0.0 0.0 7.1 0.0 20.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 64.1 0.0 0.0 0.1 0.0 0.1 68.1 25.6 4.7 0.0 31.9 0.1 456.2 155.3 169.6 296.7 171.1 317.7 300.5 410.4 343.1 164.1 287.8 459.3 365.0 41.2 345.1 209.8 121.6 587.1 414.3 1.9 2.0 1.8 4.2 2.0 2.0 3.0 2.6 3.0 2.3 3.0 3.7 1.6 3.2 9.6 0.3 133.8 2.3 4.8 1.2 1.2 1.7 1.5 1.9 0.7 2.8 0.2 0.0 0.0 0.5 124.7 0.4 11.7 0.1 11.3 14.8 0.9 2.1 0.0 22.9 0.4 0.2 0.3 1.4 2.0 48.0 58.2 0.0 6.1 3.8 22.3 0.0 0.4 0.4 0.0 24.7 12.6 9.0 0.3 40.8 10.6 39.4 69.8 0.2 407.8 0.0 0.7 0.0 0.1 0.0 64.1 2.4 0.4 12.8 0.9 0.4 0.0 0.7 1.2 8.0 0.6 2.6 2.3 0.4 162.8 0.0 0.6 1.8 TRAPPC6A "HSPC289, MGC2650, TRS33" ENSG00000007255 "Trafficking protein particle complex 6A" O75865 19 45162928-45178237 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 246.5;Proximal tubular cells: 303.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 164.5;U-266/70: 135.3" "Low region specificity" "Detected in all" HPA043043 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA043043: AB_10794650" "unprognostic (2.92e-2)" "unprognostic (1.21e-1)" "unprognostic (5.86e-2)" "unprognostic (8.42e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (1.57e-2)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" "unprognostic (2.47e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" "prognostic favorable (2.23e-6)" "unprognostic (3.85e-1)" "unprognostic (2.33e-1)" "unprognostic (1.88e-1)" "unprognostic (1.05e-2)" 27.3 32.7 25.4 14.1 28.9 48.7 31.0 27.9 35.1 20.5 19.9 33.1 18.3 21.6 19.5 25.4 29.1 15.9 21.4 24.3 25.5 57.5 59.8 18.6 34.2 30.0 27.2 23.0 28.9 17.1 20.5 12.7 29.2 39.1 11.5 4.6 30.7 16.8 35.2 56.0 28.1 7.0 27.0 42.4 32.2 24.8 26.6 20.6 38.4 15.8 17.4 23.7 24.5 33.2 7.6 42.1 9.4 18.7 15.7 11.3 18.3 2.3 8.2 2.6 5.8 12.6 38.2 76.1 40.0 4.8 22.0 15.8 3.3 6.8 1.1 42.5 30.8 28.0 3.5 14.0 33.0 12.3 28.2 27.8 37.9 2.0 12.8 10.4 8.9 48.8 27.6 57.7 4.1 104.0 30.5 42.0 11.9 164.5 21.0 52.8 10.2 93.9 27.2 26.6 44.2 18.3 16.4 77.9 29.1 16.0 45.1 39.3 3.5 6.3 6.8 4.4 2.7 135.3 43.0 57.0 14.4 25.6 10.5 25.7 59.5 30.5 78.2 60.3 94.8 92.1 105.5 81.8 91.2 93.7 110.4 95.1 4.8 113.6 62.8 87.6 112.7 86.2 25.4 28.9 27.9 35.1 24.3 25.5 30.0 27.2 29.2 27.0 26.6 33.2 28.8 44.8 51.7 5.2 61.6 58.1 64.3 149.3 55.2 13.6 66.6 71.4 17.9 68.6 71.5 58.8 2.1 122.7 63.4 41.7 246.5 53.4 15.1 56.8 26.9 33.7 83.8 23.8 2.7 42.1 43.7 24.8 29.6 65.2 40.6 63.9 42.1 113.7 72.0 13.5 2.3 84.6 148.5 56.6 67.3 94.0 19.3 45.3 108.5 5.6 114.2 54.9 60.8 4.5 10.7 24.4 73.8 10.5 39.9 35.1 61.8 303.6 62.0 13.6 13.1 23.9 34.4 14.2 68.9 43.0 83.5 88.5 72.1 72.7 81.8 71.6 TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 37.9" "Cell type enriched" "Detected in some" 8 "T-cells: 8.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.1;memory CD4 T-cell: 81.9;memory CD8 T-cell: 124.0;naive CD4 T-cell: 77.1;naive CD8 T-cell: 81.0;T-reg: 167.9" "Lineage enriched" "Detected in many" 118 "T-cells: 167.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.13e-2)" "unprognostic (4.08e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-4)" "unprognostic (5.20e-3)" "unprognostic (1.18e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (7.19e-3)" "unprognostic (2.48e-3)" "unprognostic (8.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-4)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (2.89e-1)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 7.7 0.0 1.3 1.1 0.0 0.4 1.1 0.0 1.8 1.7 0.3 0.0 1.1 0.6 2.8 0.5 0.1 0.0 0.2 0.6 2.4 17.4 0.3 0.4 0.2 0.5 0.1 0.0 0.1 0.2 1.2 2.1 0.0 0.8 0.1 0.0 0.4 3.3 0.4 0.1 5.4 2.4 0.3 0.2 37.9 0.3 0.0 14.2 2.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.6 0.1 66.1 0.1 81.9 124.0 0.1 0.1 77.1 81.0 1.4 0.4 0.5 0.4 167.9 25.2 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 24.1" "Cell type enriched" "Detected in some" 9 "T-cells: 10.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.1;memory CD4 T-cell: 143.4;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.2;naive CD8 T-cell: 80.1;T-reg: 190.6" "Lineage enriched" "Detected in many" 184 "T-cells: 190.6" "Cell line enriched" "Detected in single" 6 "JURKAT: 1.9" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.88e-3)" "unprognostic (9.98e-4)" "unprognostic (2.31e-2)" "unprognostic (2.23e-2)" "unprognostic (9.88e-5)" "unprognostic (1.94e-3)" "unprognostic (7.22e-3)" "unprognostic (9.30e-3)" "unprognostic (2.82e-3)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (7.57e-5)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.02e-1)" 0.3 0.1 0.0 3.2 0.0 1.9 0.2 0.0 0.0 0.2 0.0 0.7 1.1 0.2 1.6 0.5 0.2 1.4 0.1 0.0 0.0 2.7 0.2 1.2 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.0 0.4 0.0 0.0 0.4 1.3 0.1 0.0 4.1 1.3 0.3 0.0 24.1 0.3 0.0 6.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.0 1.1 0.1 59.1 0.2 143.4 81.1 0.3 0.3 143.2 80.1 0.7 0.2 0.2 0.1 190.6 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.0 TRAV8-3 ENSG00000211787 "T cell receptor alpha variable 8-3" A0A0A6YYJ7 14 21852558-21853006 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 71.1" "Cell type enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 138.2;T-reg: 153.1" "Lineage enriched" "Detected in many" 47 "T-cells: 153.1" "Cell line enriched" "Detected in single" 6 "JURKAT: 2.9" "Low region specificity" "Detected in single" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.74e-4)" "unprognostic (5.25e-5)" "unprognostic (8.88e-4)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (9.64e-5)" "unprognostic (8.20e-2)" "unprognostic (1.25e-2)" "unprognostic (1.38e-2)" "unprognostic (6.44e-2)" "unprognostic (2.13e-2)" "unprognostic (1.46e-1)" "unprognostic (2.66e-5)" "unprognostic (2.99e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" 0.6 0.0 0.2 6.5 0.3 3.8 2.9 0.0 1.2 2.3 0.0 3.0 2.4 0.8 16.8 1.6 8.9 5.7 0.4 0.3 0.0 0.7 1.2 3.8 40.2 0.0 0.0 0.5 0.0 0.1 0.0 0.6 0.0 1.9 4.7 0.0 2.0 0.7 0.3 0.8 2.7 1.0 0.0 9.1 2.7 3.1 0.0 71.1 0.9 1.1 30.2 6.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.4 1.2 0.1 29.7 0.1 106.6 48.4 0.3 0.6 138.2 77.0 3.2 0.2 0.3 0.9 153.1 34.6 0.2 0.3 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRAV8-6 ENSG00000211795 "T cell receptor alpha variable 8-6" A0A0B4J262 14 21978459-21979120 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 24.7" "Group enriched" "Detected in some" 19 "Spermatocytes: 1.2;Spermatogonia: 1.5;T-cells: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 89.3;memory CD8 T-cell: 64.2;naive CD4 T-cell: 92.6;naive CD8 T-cell: 38.7;T-reg: 125.0" "Lineage enriched" "Detected in many" 45 "T-cells: 125.0" "Cell line enriched" "Detected in single" 97 "JURKAT: 9.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (9.23e-4)" "unprognostic (5.47e-3)" "unprognostic (1.27e-3)" "unprognostic (7.80e-2)" "unprognostic (7.74e-5)" "unprognostic (2.88e-3)" "unprognostic (5.41e-3)" "unprognostic (2.59e-3)" "unprognostic (2.24e-2)" "unprognostic (9.25e-2)" "unprognostic (2.92e-1)" "unprognostic (9.78e-5)" "unprognostic (4.65e-1)" "unprognostic (2.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-3)" 0.2 0.0 0.0 3.0 0.0 0.8 0.8 0.0 0.0 0.4 0.0 0.9 0.7 0.3 0.7 0.3 0.3 2.0 0.2 0.0 0.0 0.3 0.3 1.4 10.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.1 0.1 0.2 1.3 0.4 0.1 2.9 1.5 0.4 0.0 24.7 0.1 0.1 8.2 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 17.9 0.2 89.3 64.2 0.1 0.1 92.6 38.7 2.8 0.1 0.1 0.2 125.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TRBJ2-7 "TCRBJ2S7, TRBJ27" ENSG00000211771 "T cell receptor beta joining 2-7" A0A0A0MT78 7 142797456-142797502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 45.4;lymphoid tissue: 155.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 10.8" "Group enriched" "Detected in all" 7 "MAIT T-cell: 1275.2;memory CD4 T-cell: 2387.1;memory CD8 T-cell: 2649.6;naive CD4 T-cell: 2393.9;naive CD8 T-cell: 2831.0;T-reg: 4224.6" "Lineage enriched" "Detected in all" 18 "T-cells: 4224.6" "Cell line enhanced" "Detected in some" "JURKAT: 43.8;MOLT-4: 212.6;U-698: 55.5" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.07e-3)" "unprognostic (9.26e-3)" "unprognostic (4.37e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.14e-3)" "unprognostic (2.57e-3)" "unprognostic (6.68e-3)" "unprognostic (9.60e-2)" "unprognostic (2.17e-2)" "unprognostic (6.18e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (7.27e-2)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" 3.5 4.6 1.9 96.9 3.1 45.4 2.5 1.5 4.2 0.0 0.0 7.5 18.1 5.2 0.0 0.7 0.5 9.5 0.8 0.7 2.8 0.4 0.0 4.4 108.7 1.0 2.3 2.8 5.1 0.0 0.0 1.1 0.9 2.3 6.2 0.3 3.6 0.9 0.0 0.0 36.0 0.0 0.9 54.0 25.2 2.0 10.8 155.0 0.0 0.0 47.7 4.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 8.3 43.8 0.0 0.0 0.0 3.7 212.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 42.7 6.9 10.3 360.2 6.3 1275.2 233.4 2387.1 2649.6 6.9 233.7 2393.9 2831.0 64.7 122.4 13.1 9.8 4224.6 1638.0 1.9 3.1 1.5 4.2 0.7 2.8 1.0 2.3 0.9 0.9 10.8 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRBV10-3 "TCRBV10S3, TCRBV12S1A1N2, TRBV103" ENSG00000275791 "T cell receptor beta variable 10-3" A0A0K0K1G6 7 142544212-142544685 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 88.6" "Group enriched" "Detected in some" 5 "Late spermatids: 1.7;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 160.1;T-reg: 203.1" "Lineage enriched" "Detected in single" 375 "T-cells: 203.1" "Cell line enriched" "Detected in single" 53 "MOLT-4: 49.7" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.61e-3)" "unprognostic (4.86e-3)" "unprognostic (2.44e-2)" "unprognostic (8.96e-3)" "unprognostic (3.16e-1)" "unprognostic (4.23e-6)" "unprognostic (9.84e-4)" "unprognostic (7.96e-2)" "unprognostic (4.05e-2)" "unprognostic (7.99e-4)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (9.59e-6)" "unprognostic (5.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" 0.3 0.2 0.0 8.0 0.0 2.8 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.3 0.2 1.0 0.1 0.0 0.0 0.1 0.4 0.5 16.8 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.9 0.1 0.0 0.0 1.4 0.3 0.0 2.1 2.3 0.1 0.1 88.6 0.2 0.0 12.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.9 0.0 49.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 9.3 0.4 77.0 160.1 0.0 0.3 101.7 41.2 0.3 0.1 0.5 0.5 203.1 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 53.4" "Cell type enriched" "Detected in some" 5 "T-cells: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 50.8;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.1;naive CD8 T-cell: 53.5;T-reg: 88.5" "Lineage enriched" "Detected in single" 191 "T-cells: 88.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.62e-3)" "unprognostic (8.91e-4)" "unprognostic (1.14e-2)" "unprognostic (5.81e-3)" "unprognostic (2.38e-2)" "unprognostic (2.29e-4)" "unprognostic (3.96e-3)" "unprognostic (3.62e-3)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (9.78e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" 0.6 0.1 0.0 5.7 0.0 0.7 0.7 0.1 0.3 0.8 0.0 1.2 0.5 0.5 0.0 0.4 0.3 3.7 0.1 0.1 0.0 0.2 0.7 1.1 28.5 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.1 0.4 2.1 0.0 0.2 0.3 0.1 0.4 3.0 0.2 0.0 3.8 2.9 0.1 0.1 53.4 0.5 0.2 1.9 0.5 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.1 13.5 0.4 50.8 40.2 0.1 0.0 71.1 53.5 0.4 0.1 0.2 0.0 88.5 15.5 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 TRBV2 "TCRBV22S1A2N1T, TCRBV2S1" ENSG00000226660 "T cell receptor beta variable 2" A0A1B0GX68 7 142300924-142301432 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "lymphoid tissue: 89.2" "Cell type enriched" "Detected in single" 80 "T-cells: 8.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 120.3;memory CD8 T-cell: 64.5;naive CD4 T-cell: 71.5;naive CD8 T-cell: 44.5;T-reg: 122.7" "Lineage enriched" "Detected in many" 21 "T-cells: 122.7" "Cell line enriched" "Detected in single" 10 "RPMI-8226: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.62e-4)" "unprognostic (4.94e-4)" "unprognostic (5.79e-2)" "unprognostic (1.29e-3)" "unprognostic (1.09e-1)" "unprognostic (4.71e-5)" "unprognostic (3.60e-2)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (1.16e-2)" "unprognostic (1.94e-2)" "unprognostic (1.77e-1)" "unprognostic (3.70e-5)" "unprognostic (3.83e-1)" "unprognostic (6.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.41e-2)" 1.1 0.3 0.0 8.3 0.0 3.9 1.2 0.0 0.1 1.1 0.0 2.6 2.5 0.3 1.1 1.7 0.2 2.4 0.1 0.0 0.0 0.4 0.9 1.6 25.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 2.1 0.0 0.3 0.5 0.0 0.3 1.7 0.8 0.0 6.8 3.5 0.3 0.0 89.2 0.5 0.3 22.1 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.9 0.0 5.5 0.1 120.3 64.5 0.3 0.1 71.5 44.5 1.2 0.1 0.1 5.8 122.7 29.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 161.4" "Cell type enriched" "Detected in some" 15 "T-cells: 26.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 351.7" "Lineage enriched" "Detected in many" 115 "T-cells: 351.7" "Group enriched" "Detected in some" 8 "Karpas-707: 2.4;MOLT-4: 5.0;REH: 2.5;RH-30: 3.0" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "prognostic favorable (4.40e-5)" "unprognostic (1.39e-2)" "prognostic favorable (8.49e-4)" "unprognostic (8.83e-2)" "unprognostic (2.69e-3)" "unprognostic (4.34e-2)" "unprognostic (8.75e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.30e-2)" "unprognostic (8.86e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (3.41e-2)" 1.7 0.2 0.1 13.6 0.1 5.1 0.6 0.1 0.2 0.6 0.0 2.4 0.5 0.3 0.0 0.7 0.7 3.2 0.2 0.1 0.0 0.5 0.6 2.7 53.3 0.2 0.0 0.5 0.2 0.0 0.8 0.0 0.3 0.9 3.1 0.0 0.5 0.2 0.1 1.9 6.0 0.9 0.1 7.3 3.6 0.3 0.1 161.4 1.0 0.0 6.0 2.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 5.0 0.2 0.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.6 0.2 4.6 0.3 231.9 1.1 192.7 76.4 0.6 0.6 144.0 58.9 2.3 0.3 0.8 0.4 351.7 50.2 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" 0.2 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.4 2.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 1.0 0.0 0.9 0.2 0.0 1.3 1.6 0.4 0.5 6.7 0.1 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 9.0 0.0 5.7 0.0 15.4 15.5 0.0 0.0 11.4 26.6 0.2 0.0 0.0 0.0 23.2 4.6 0.1 2.7 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Cell type enriched" "Detected in some" 4 "T-cells: 6.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Group enriched" "Detected in some" 4 "HAP1: 2.9;JURKAT: 3.3;U-937: 3.6" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" 0.6 0.5 0.0 3.5 0.6 1.9 0.8 0.0 0.3 0.7 0.0 1.2 1.0 0.9 0.1 0.8 0.2 1.8 0.2 0.0 0.0 0.4 0.5 1.7 19.7 0.0 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.5 1.7 0.0 1.7 0.0 0.3 0.2 2.8 0.2 0.0 4.8 1.9 5.7 0.2 81.6 0.6 0.8 10.6 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.4 0.1 0.6 3.3 0.0 10.4 0.1 61.1 112.2 0.1 0.1 48.2 75.8 0.8 0.1 0.2 0.1 94.7 27.3 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 TRBV29-1 "TCRBV29S1, TCRBV4S1A1T, TRBV291" ENSG00000232869 "T cell receptor beta variable 29-1" A0A5B7 7 142740206-142740894 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 98.5" "Cell type enriched" "Detected in single" 11 "T-cells: 4.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "MAIT T-cell: 45.1;memory CD4 T-cell: 128.6;memory CD8 T-cell: 83.2;naive CD4 T-cell: 137.8;naive CD8 T-cell: 110.8;T-reg: 178.2" "Lineage enriched" "Detected in many" 69 "T-cells: 178.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "prognostic favorable (1.23e-4)" "unprognostic (9.31e-4)" "unprognostic (1.29e-1)" "unprognostic (8.13e-3)" "unprognostic (3.28e-2)" "unprognostic (3.47e-4)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.45e-1)" "unprognostic (2.46e-2)" "unprognostic (2.29e-1)" "unprognostic (2.05e-1)" 0.8 0.3 0.0 6.5 0.0 4.4 1.2 0.3 0.1 1.4 0.1 1.9 2.7 0.6 0.0 1.0 0.3 2.6 0.2 0.0 0.0 0.4 1.2 1.5 21.7 0.0 0.0 0.6 21.2 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.7 0.6 0.1 0.4 3.9 1.2 0.0 5.4 2.3 0.1 0.0 98.5 0.6 0.5 23.4 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 0.7 0.1 45.1 2.0 128.6 83.2 0.1 1.8 137.8 110.8 2.5 0.2 0.3 0.7 178.2 51.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" 0.3 0.0 0.0 4.8 0.0 1.1 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.7 9.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.3 1.9 0.1 0.0 2.6 1.6 0.2 0.0 44.0 0.2 0.0 8.9 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 2.6 0.2 11.0 0.4 166.1 65.4 0.4 0.4 211.6 128.7 2.6 0.5 0.5 0.3 295.5 82.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 22.1;pancreas: 11.6" "Group enriched" "Detected in some" 9 "Plasma cells: 6.1;T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 115.7" "Lineage enriched" "Detected in many" 115 "T-cells: 115.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 11.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.48e-3)" "unprognostic (6.75e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-3)" "unprognostic (5.82e-2)" "unprognostic (2.79e-2)" "unprognostic (1.59e-2)" "unprognostic (4.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-4)" "unprognostic (2.77e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" 0.2 0.1 0.0 2.4 0.2 1.2 0.1 0.0 0.0 0.2 0.0 0.7 0.8 0.0 0.1 0.3 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.4 8.2 0.2 0.0 0.0 11.6 0.0 0.0 0.0 0.2 0.2 1.0 0.7 0.5 0.0 0.2 0.3 1.1 0.0 0.0 2.2 1.0 0.2 0.0 22.1 0.2 0.0 8.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.0 1.3 0.1 2.1 0.0 49.7 26.7 0.0 0.1 62.8 36.4 1.0 0.1 0.1 0.1 115.7 18.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV6-5 "TCRBV13S1, TCRBV6S5, TRBV65" ENSG00000211721 "T cell receptor beta variable 6-5" A0A0K0K1A5 7 142450947-142451448 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 82.3" "Cell type enriched" "Detected in single" 121 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 133.8;T-reg: 137.9" "Lineage enriched" "Detected in many" 54 "T-cells: 137.9" "Cell line enriched" "Detected in some" 8 "HL-60: 61.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.42e-3)" "unprognostic (7.43e-4)" "unprognostic (1.11e-2)" "unprognostic (2.20e-3)" "unprognostic (1.38e-1)" "unprognostic (8.63e-5)" "unprognostic (1.55e-2)" "unprognostic (1.51e-3)" "unprognostic (8.72e-3)" "unprognostic (2.11e-3)" "unprognostic (7.03e-2)" "unprognostic (4.82e-1)" "prognostic unfavorable (5.40e-5)" "unprognostic (3.12e-2)" "unprognostic (4.17e-2)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" 0.4 0.2 0.0 4.1 0.0 2.3 0.5 0.0 0.1 0.4 0.0 0.9 1.0 0.2 0.0 0.2 0.3 1.6 0.1 0.0 0.0 0.1 0.3 2.4 16.1 0.0 0.0 0.3 7.3 0.0 0.0 0.1 0.0 0.3 1.2 0.2 0.4 0.1 0.0 0.3 2.0 0.3 0.0 3.4 1.6 0.1 0.0 82.3 0.4 0.7 12.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.5 0.2 0.2 1.0 0.1 32.8 0.3 78.7 76.2 0.1 0.4 92.0 133.8 2.5 0.2 0.4 0.4 137.9 59.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.1 TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 33.0" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Group enriched" "Detected in some" 9 "JURKAT: 55.7;MOLT-4: 93.6;U-937: 49.0" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.9 0.1 0.0 15.0 0.1 0.0 2.2 0.0 0.2 2.2 0.0 1.2 1.7 0.0 35.6 0.6 0.5 0.0 0.2 0.0 1.1 0.5 0.3 5.5 49.0 0.0 0.0 0.1 0.2 0.0 1.0 0.1 0.0 0.3 4.6 0.0 0.4 0.4 0.0 0.2 4.7 1.1 0.0 5.8 4.7 0.0 0.2 85.5 0.7 0.0 43.0 2.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.0 0.0 0.0 0.0 93.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.0 0.0 49.0 0.0 1.1 2.3 0.7 11.9 1.2 55.5 0.7 397.4 178.6 2.7 0.7 302.2 110.6 1.2 0.5 1.9 7.2 570.3 104.9 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRGC1 "C1, TCRGC1" ENSG00000211689 "T cell receptor gamma constant 1" 7 38257879-38265678 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 31.7;prostate: 76.6" "Group enriched" "Detected in some" 5 "dendritic cells: 95.8;NK-cells: 230.7;Prostatic glandular cells: 61.9;T-cells: 65.6" "Cancer enriched" "Detected in some" 141 "prostate cancer: 107.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "gdT-cell: 384.7" "Lineage enriched" "Detected in many" 4 "T-cells: 384.7" "Cell line enhanced" "Detected in some" "HL-60: 21.0;MCF7: 89.8;SK-BR-3: 49.6;U-937: 45.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.37e-2)" "unprognostic (2.38e-4)" "unprognostic (3.43e-3)" "unprognostic (6.04e-4)" "unprognostic (1.04e-2)" "unprognostic (3.77e-3)" "unprognostic (1.33e-3)" "unprognostic (3.80e-2)" "unprognostic (3.55e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (2.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "unprognostic (8.36e-2)" "unprognostic (2.56e-2)" 0.6 0.2 1.6 1.1 1.6 31.7 2.1 1.4 2.0 0.1 1.1 0.5 1.0 0.2 0.5 0.1 0.3 1.0 0.2 1.4 1.4 0.8 0.8 1.9 2.0 1.7 1.5 0.1 0.0 0.0 0.2 0.5 1.6 76.6 0.6 0.0 0.4 0.2 0.1 0.1 1.4 0.2 1.6 6.0 0.6 0.4 2.1 7.0 0.3 0.0 1.3 0.6 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 21.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 49.6 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 3.8 0.3 0.5 384.7 0.4 56.7 0.2 6.8 33.5 0.3 0.0 2.3 21.7 1.8 87.5 0.3 0.5 0.1 43.7 1.6 1.6 1.4 2.0 1.4 1.4 1.7 1.5 1.6 1.6 2.1 1.5 0.5 0.0 1.1 0.0 2.1 0.0 1.3 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.6 0.0 0.0 0.0 95.8 0.1 0.0 0.0 2.3 0.0 0.1 0.5 1.2 2.7 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 2.2 0.9 0.1 0.0 0.0 0.2 0.0 1.9 0.0 0.9 0.0 2.1 0.0 0.0 19.5 0.0 230.7 0.0 0.0 0.0 0.0 0.0 14.3 61.9 0.0 0.3 0.7 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 65.6 0.0 0.3 1.2 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRGJ1 "J1, TCRGJ1" ENSG00000211690 "T cell receptor gamma joining 1" A0A075B6S0 7 38269491-38269540 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;lymphoid tissue: 13.0;prostate: 57.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 293.4;MAIT T-cell: 274.9;memory CD8 T-cell: 299.2;naive CD8 T-cell: 194.4" "Lineage enriched" "Detected in many" 14 "T-cells: 299.2" "Group enriched" "Detected in some" 6 "HL-60: 11.7;MCF7: 15.9;SK-BR-3: 14.8;U-937: 13.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" 0.0 0.0 3.0 3.1 1.0 17.2 2.3 0.3 1.7 0.0 0.4 1.1 4.7 0.2 1.9 0.0 1.2 0.7 0.3 0.4 0.5 1.0 0.5 1.2 5.1 2.7 1.7 0.6 3.0 0.0 0.0 0.0 1.9 57.9 2.4 0.0 0.7 0.0 0.0 0.0 4.9 0.7 1.6 13.0 0.7 1.1 2.4 2.0 0.1 0.0 1.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 15.9 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 1.1 0.3 0.3 293.4 0.6 274.9 0.2 55.8 299.2 0.3 0.2 15.0 194.4 2.2 21.7 0.7 0.6 1.1 52.8 3.0 1.0 0.3 1.7 0.4 0.5 2.7 1.7 1.9 1.6 2.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRGJP "JP, TCRGJP" ENSG00000211691 "T cell receptor gamma joining P" 7 38273587-38273647 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "bone marrow: 43.1;prostate: 95.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 46 "gdT-cell: 2370.0" "Lineage enriched" "Detected in many" 46 "T-cells: 2370.0" "Group enriched" "Detected in some" 10 "MCF7: 26.9;SK-BR-3: 60.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" 0.0 0.0 1.4 5.2 1.0 43.1 0.7 0.3 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 1.1 1.2 0.8 0.7 1.2 0.0 0.0 0.4 1.1 0.8 0.0 0.0 0.0 0.0 0.4 1.1 95.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6.7 2.8 2.5 1.5 0.6 0.0 0.0 0.6 1.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 1.7 0.5 2370.0 3.2 49.6 0.8 2.0 26.9 0.8 0.3 0.4 18.5 10.2 51.9 0.9 2.0 0.6 210.4 1.4 1.0 0.3 1.4 0.8 0.7 1.1 0.8 1.1 0.6 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRGV9 "TCRGV9, V2" ENSG00000211695 "T cell receptor gamma variable 9" Q99603 7 38317017-38318861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9;prostate: 5.5" "Group enriched" "Detected in some" 4 "dendritic cells: 14.6;NK-cells: 22.6;T-cells: 37.7" "Cancer enriched" "Detected in single" 126 "prostate cancer: 13.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "gdT-cell: 426.5" "Lineage enriched" "Detected in many" 13 "T-cells: 426.5" "Group enriched" "Detected in some" 6 "MCF7: 7.7;NB-4: 2.4;U-937: 8.6" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (3.98e-3)" "unprognostic (4.43e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (2.41e-1)" "unprognostic (6.60e-4)" "unprognostic (1.29e-1)" "unprognostic (4.95e-1)" 0.4 0.0 0.4 0.5 0.7 1.1 0.1 0.4 0.5 0.1 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.5 0.0 0.2 0.4 0.5 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.7 5.5 0.2 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.4 1.6 0.3 0.1 0.5 1.5 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.7 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 0.0 0.3 0.1 426.5 0.6 29.0 0.1 1.6 19.7 0.4 0.0 0.7 8.4 1.4 33.2 0.1 0.5 0.1 38.8 0.4 0.7 0.4 0.5 0.5 0.5 0.7 0.5 0.7 0.4 0.5 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 4.6 0.0 0.0 0.1 1.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;pancreas: 10.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 216.9;Inhibitory neurons: 292.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Group enriched" "Detected in many" 5 "basal ganglia: 4.9;cerebellum: 4.4;cerebral cortex: 2.5;hippocampal formation: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 30.3;BJ hTERT+: 29.1;EFO-21: 15.3;HBF TERT88: 10.3;hTERT-RPE1: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 7300000 "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 3.6 0.9 0.1 0.3 4.9 0.4 0.8 4.4 2.5 3.7 0.0 1.1 2.4 1.2 0.6 0.2 1.1 0.8 0.8 7.6 0.0 5.1 0.5 1.4 0.1 0.0 0.9 3.2 10.3 0.0 0.1 0.1 0.0 1.3 0.5 0.8 0.8 2.8 0.2 0.2 2.1 0.4 0.0 2.5 0.3 0.7 0.0 0.1 0.0 0.4 0.3 1.2 2.3 0.0 3.6 0.0 0.6 0.0 1.6 0.0 9.5 30.3 29.1 2.9 1.9 0.0 0.0 0.0 15.3 4.3 3.0 0.4 5.4 0.0 10.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 2.3 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 0.0 0.0 0.0 9.5 6.7 2.9 0.1 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 4.4 2.5 7.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 1.5 0.0 1.8 0.0 0.1 0.0 7.1 3.9 0.0 35.9 0.1 0.4 0.2 0.0 0.0 216.9 2.6 0.4 4.7 0.0 0.3 0.0 0.1 0.4 1.4 0.2 0.0 292.7 3.5 0.0 0.0 0.0 62.8 29.5 0.7 0.0 2.8 0.0 0.4 0.0 38.2 4.0 2.2 3.9 13.5 0.0 0.2 15.8 9.1 0.7 0.6 0.0 37.4 0.6 0.2 0.7 0.0 0.0 0.1 0.1 0.2 1.6 0.1 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "AF22: 146.5;HMC-1: 196.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 7.5 25.7 6.0 6.9 6.8 10.6 9.1 5.8 7.0 6.4 5.2 8.1 10.0 8.8 8.4 9.0 5.7 5.3 10.4 6.0 7.1 8.0 23.1 11.4 8.0 6.8 6.4 30.0 10.8 14.2 3.8 12.3 6.3 11.7 9.2 12.2 8.3 5.2 13.9 8.6 9.7 7.6 6.2 7.2 11.6 27.3 8.2 17.3 9.1 16.4 7.8 7.5 6.1 9.0 15.0 18.1 146.5 42.7 9.6 8.9 11.4 13.7 14.4 10.5 10.2 28.7 13.6 28.7 13.2 13.2 21.5 7.9 71.9 11.4 15.4 22.1 17.7 63.1 13.1 88.9 13.1 49.8 196.8 7.9 11.8 8.8 13.9 7.3 25.0 15.4 72.6 17.1 12.7 29.2 85.2 44.8 56.3 77.6 16.0 66.5 17.3 24.2 23.6 43.9 30.3 68.8 25.5 22.6 7.5 50.6 15.5 32.3 10.7 12.1 9.9 21.4 19.1 15.6 18.2 47.8 20.1 32.1 18.0 0.3 0.6 1.0 0.5 0.6 0.1 0.2 0.4 0.3 0.5 0.3 0.4 0.5 0.9 0.6 0.3 0.3 0.7 0.2 6.0 6.8 5.8 7.0 6.0 7.1 6.8 6.4 6.3 6.2 8.2 9.0 29.0 51.3 46.9 26.1 9.5 13.9 13.4 13.8 10.8 13.6 14.7 14.4 39.7 20.0 18.8 7.3 16.7 28.4 14.9 12.2 5.9 7.1 70.4 16.7 22.9 18.9 10.1 31.3 27.9 12.4 15.2 16.0 20.4 25.2 40.4 85.2 14.3 31.9 10.3 40.4 46.6 10.9 14.2 9.5 14.9 38.7 14.0 13.8 14.2 21.5 12.2 23.3 9.2 64.3 67.1 9.5 9.5 16.1 13.7 12.2 6.8 10.6 14.5 22.4 13.1 21.5 17.6 72.8 14.7 22.2 11.8 22.2 15.8 34.6 19.4 12.8 TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113090 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 22.1;stomach 1: 6.0;urinary bladder: 8.6" "Group enriched" "Detected in some" 4 "Distal enterocytes: 409.1;Paneth cells: 404.9;Proximal enterocytes: 193.3;Urothelial cells: 227.9" "Group enriched" "Detected in many" 5 "cervical cancer: 6.7;colorectal cancer: 25.8;pancreatic cancer: 11.4;stomach cancer: 19.8;urothelial cancer: 12.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 726 "RT4: 294.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA074175 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA074175: " "unprognostic (1.37e-1)" "unprognostic (7.78e-3)" "unprognostic (1.83e-1)" "unprognostic (7.05e-3)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (6.13e-2)" "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 22.1 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.4 12.1 0.1 0.0 0.0 6.0 3.3 0.0 0.0 0.0 0.0 0.0 8.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 294.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.1 12.3 2.5 0.0 0.0 0.4 0.3 5.7 4.3 3.0 0.0 0.0 0.0 0.2 409.1 0.0 2.7 0.2 25.7 0.2 0.4 5.4 2.7 0.0 1.7 0.0 0.3 73.9 1.1 4.5 0.0 0.0 0.0 0.1 0.0 0.0 52.3 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 404.9 0.0 0.2 2.7 193.3 0.6 14.2 0.0 0.0 0.2 0.5 1.8 0.2 0.0 0.0 0.0 0.8 0.0 25.6 227.9 TRIM36 "HAPRIN, RBCC728, RNF98" ENSG00000152503 "Tripartite motif containing 36" Q9NQ86 5 115124762-115180546 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 44.2;testis: 174.3" "Group enriched" "Detected in many" 26 "Early spermatids: 2120.7;Late spermatids: 4980.3" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.8;non-classical monocyte: 6.5" "Group enriched" "Detected in many" 48 "dendritic cells: 5.8;granulocytes: 3.2;monocytes: 6.5" "Cell line enhanced" "Detected in many" "RH-30: 24.5;SCLC-21H: 28.3;SH-SY5Y: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061321 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA061321: AB_2684479" "unprognostic (6.36e-2)" "unprognostic (2.99e-1)" "unprognostic (4.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.31e-2)" "unprognostic (5.33e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (2.82e-13)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (6.80e-3)" 0.5 1.3 13.2 1.6 16.7 0.5 4.4 3.9 14.2 2.4 8.7 7.5 14.1 0.9 0.6 0.3 2.2 0.5 0.2 16.1 15.7 0.3 0.4 1.8 0.3 17.0 10.5 4.7 1.6 0.2 13.4 1.1 16.1 10.0 7.5 44.2 0.5 0.6 0.2 0.6 13.8 0.8 10.2 0.5 4.6 174.3 12.7 0.7 0.2 0.4 0.4 0.4 1.3 20.0 3.6 0.9 1.6 8.4 0.2 0.1 2.0 0.7 2.8 1.5 1.7 1.2 1.7 0.0 1.4 0.1 11.9 1.1 7.9 1.5 1.1 0.6 2.7 6.0 3.3 1.7 0.3 6.0 4.8 0.1 1.4 0.7 2.0 1.9 0.1 11.2 0.2 7.9 2.3 4.6 1.6 5.4 6.7 0.6 3.8 1.3 24.5 1.9 0.9 0.1 28.3 19.6 5.3 0.5 3.2 0.8 5.8 7.4 0.7 2.3 1.8 1.7 2.7 1.2 0.8 0.0 2.5 3.4 1.1 0.0 1.2 3.2 0.0 1.3 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 0.3 0.0 6.5 1.2 0.0 0.6 13.2 16.7 3.9 14.2 16.1 15.7 17.0 10.5 16.1 10.2 12.7 20.0 0.4 0.0 3.4 1.0 0.1 2.3 0.6 0.2 0.6 5.0 14.8 9.3 2.3 0.0 0.5 1.8 56.3 0.0 1.8 27.6 0.0 0.4 2120.7 3.3 0.3 2.0 3.5 0.0 39.7 1.8 0.5 1.4 6.6 1.1 1.3 0.1 0.4 0.0 2.8 5.0 14.0 15.8 2.0 1.9 18.1 4980.3 14.9 6.0 8.8 29.0 3.4 6.9 0.0 2.5 53.4 1.5 20.4 12.8 0.1 12.1 28.2 0.2 5.0 76.8 6.6 2.0 2.3 136.2 26.9 1.2 1.3 0.3 0.7 0.1 8.8 0.2 TRNP1 "C1orf225, TRNP" ENSG00000253368 "TMF1 regulated nuclear protein 1" Q6NT89 1 26993692-27000886 "Predicted intracellular proteins" "Cell cycle, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.3;retina: 84.3;stomach 1: 124.6" "Group enriched" "Detected in many" 6 "Bipolar cells: 448.0;Gastric mucus-secreting cells: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 208.3;BJ hTERT+: 206.4;EFO-21: 171.4;RPTEC TERT1: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.41e-1)" "unprognostic (7.15e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-3)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.53e-1)" "unprognostic (8.39e-3)" "unprognostic (1.64e-1)" "unprognostic (1.90e-1)" "unprognostic (9.71e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "unprognostic (1.88e-1)" "unprognostic (2.55e-2)" 11.7 5.0 18.7 1.9 20.6 0.0 9.3 19.4 41.8 17.0 2.9 15.8 4.4 17.6 4.1 85.3 16.8 17.5 30.6 23.3 22.9 22.9 4.5 9.6 0.8 30.5 18.6 4.4 21.3 21.6 13.6 7.5 30.3 10.1 2.5 84.3 7.8 10.2 2.4 9.7 6.6 10.4 10.7 5.4 124.6 2.1 29.7 2.1 4.2 1.1 9.7 20.0 18.1 19.2 30.8 88.0 21.1 13.6 162.3 208.3 0.2 153.1 206.4 13.7 6.5 12.1 14.5 0.0 171.4 143.5 5.6 31.0 11.5 62.0 17.0 0.5 8.9 0.1 2.1 63.0 117.3 0.1 0.4 120.3 128.8 7.2 131.0 13.4 13.6 1.0 2.3 0.1 33.7 4.6 0.3 2.3 27.9 136.7 143.7 8.6 0.4 2.4 174.2 9.1 35.5 2.6 29.5 6.3 73.5 13.1 3.0 0.8 71.9 4.6 34.7 73.6 6.7 0.4 0.5 0.6 4.8 0.8 8.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 18.7 20.6 19.4 41.8 23.3 22.9 30.5 18.6 30.3 10.7 29.7 19.2 3.4 19.2 0.6 1.3 0.8 7.4 13.9 1.2 4.6 448.0 6.4 28.4 27.9 32.9 2.4 9.2 8.4 0.2 1.5 0.4 31.3 7.0 0.8 22.2 8.1 2.7 12.0 0.0 7.9 30.9 0.1 3.0 116.7 17.3 0.0 0.4 1.4 1.1 0.2 8.4 11.6 3.5 0.0 3.7 1.1 0.9 9.6 1.7 3.6 1.9 1.3 43.2 0.0 3.0 1.4 25.3 0.1 3.0 0.2 6.6 0.3 0.3 5.6 35.7 26.3 0.8 19.7 1.6 0.8 22.5 8.8 0.0 0.9 0.0 0.3 10.8 TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 905.0;Excitatory neurons: 390.3;Inhibitory neurons: 186.9;Muller glia cells: 184.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HAP1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" 0.7 0.6 22.0 0.1 30.4 0.2 0.1 40.5 9.6 1.0 801.0 0.2 0.8 1.1 1.3 0.1 0.4 0.4 0.8 39.3 27.8 16.5 0.2 0.1 0.1 36.7 46.8 3.6 0.5 0.0 2.9 0.1 20.8 0.5 0.1 23.0 0.1 2.5 0.3 0.1 0.0 0.2 25.2 0.3 0.6 5.1 41.6 0.2 0.9 0.1 0.0 0.1 0.4 15.4 0.0 0.0 0.9 0.0 1.1 2.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 17.2 0.0 0.1 0.0 0.1 0.1 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.2 0.0 0.0 1.0 4.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.9 0.0 1.1 0.0 0.2 0.0 0.3 0.2 0.0 0.0 3.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 22.0 30.4 40.5 9.6 39.3 27.8 36.7 46.8 20.8 25.2 41.6 15.4 0.3 3.2 3.0 905.0 0.5 0.4 0.9 0.0 0.6 16.4 0.3 0.5 5.3 5.7 2.5 16.5 66.7 0.1 0.2 0.1 5.9 0.1 4.8 1.4 1.0 1.3 15.4 0.0 390.3 0.2 0.1 3.0 0.0 3.2 0.0 1.4 0.7 0.3 0.2 1.7 186.9 0.1 0.0 0.9 1.4 2.3 5.6 0.8 0.0 56.2 0.2 184.5 1.0 105.6 8.3 0.1 0.1 9.1 0.0 0.5 0.1 33.3 0.8 10.1 0.0 3.5 1.3 1.3 0.6 0.0 0.9 0.3 0.9 0.6 0.0 0.3 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPM5 "LTRPC5, MTR1" ENSG00000070985 "Transient receptor potential cation channel subfamily M member 5" Q9NZQ8 11 2404515-2423045 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.8;intestine: 3.3;pancreas: 2.4;seminal vesicle: 1.7" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 9.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (6.47e-5)" "unprognostic (6.81e-4)" "unprognostic (7.90e-3)" "unprognostic (1.18e-1)" "unprognostic (1.13e-2)" "unprognostic (2.24e-2)" "unprognostic (4.75e-1)" "unprognostic (1.53e-1)" "unprognostic (2.36e-1)" "unprognostic (3.19e-1)" "unprognostic (5.07e-3)" "unprognostic (2.40e-1)" "unprognostic (5.21e-1)" "unprognostic (5.72e-2)" "unprognostic (4.91e-2)" 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 2.0 2.9 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 1.7 0.0 0.0 3.3 0.0 0.0 0.1 0.3 0.6 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.1 TRPM8 ENSG00000144481 "Transient receptor potential cation channel subfamily M member 8" Q7Z2W7 2 233917373-234019522 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 57 "liver: 31.5;prostate: 80.2" "Group enriched" "Detected in some" 5 "Hepatocytes: 45.2;Prostatic glandular cells: 16.3" "Cancer enriched" "Detected in some" 27 "prostate cancer: 72.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 5.5;RPTEC TERT1: 8.1;SK-MEL-30: 8.9;WM-115: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.41e-3)" "unprognostic (7.91e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (4.60e-3)" "prognostic favorable (7.15e-4)" "unprognostic (3.28e-2)" "unprognostic (3.71e-1)" "unprognostic (9.88e-3)" "unprognostic (7.10e-3)" "unprognostic (4.69e-2)" "unprognostic (3.36e-5)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" 0.0 0.2 0.2 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 31.5 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.5 0.0 0.3 80.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.6 8.1 0.0 0.5 0.3 0.0 0.1 8.9 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 1.2 2.0 0.0 0.7 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.3 0.1 0.9 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 5.5 0.1 0.0 0.7 0.2 0.0 1.1 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 2.3 1.2 0.6 0.5 0.0 2.7 0.3 1.7 0.0 0.3 0.0 4.4 0.0 0.1 0.7 45.2 0.3 0.0 0.9 0.0 0.0 0.6 0.8 3.9 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 16.3 0.0 0.0 0.0 0.2 0.0 0.4 0.2 1.3 0.6 0.0 0.1 0.0 0.5 0.0 0.0 4.1 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TRPV6 "CaT1, ECAC2" ENSG00000165125 "Transient receptor potential cation channel subfamily V member 6" Q9H1D0 7 142871208-142885745 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 38.3;prostate: 23.5;salivary gland: 69.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Collecting duct cells: 27.6;Cytotrophoblasts: 17.0;Ductal cells: 80.1;Early spermatids: 25.9;Late spermatids: 37.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 16.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.6;HaCaT: 18.0;RT4: 30.7;SK-BR-3: 23.5;T-47d: 52.8" "Low region specificity" "Detected in single" HPA062864 Approved NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA062864: AB_2684885" "unprognostic (9.85e-2)" "unprognostic (1.60e-2)" "unprognostic (6.29e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "unprognostic (5.43e-2)" "unprognostic (3.50e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-2)" "unprognostic (3.27e-2)" "unprognostic (8.49e-2)" "unprognostic (9.39e-3)" "unprognostic (1.69e-1)" "unprognostic (7.17e-3)" "unprognostic (3.53e-2)" 0.0 0.0 0.5 0.0 0.6 0.1 4.2 0.6 1.1 0.5 0.6 0.1 8.1 0.1 0.3 2.7 0.2 8.2 0.1 0.5 0.6 5.2 0.9 0.2 0.0 0.6 0.6 0.0 38.3 1.5 0.5 11.9 0.8 23.5 0.0 0.0 69.3 1.6 0.0 6.4 2.2 0.0 0.6 0.0 4.5 1.2 0.6 0.0 1.8 0.0 0.2 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 1.9 0.1 0.0 23.5 0.6 0.9 52.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 1.1 0.5 0.6 0.6 0.6 0.8 0.6 0.6 0.6 0.0 3.2 0.0 0.0 0.0 0.5 1.1 0.2 5.2 0.6 2.4 2.0 1.9 18.6 1.4 27.6 0.0 17.0 0.1 0.1 0.0 80.1 25.9 0.7 0.2 0.2 0.0 0.0 0.1 3.3 0.8 0.2 3.6 1.6 0.0 0.0 0.4 0.0 1.6 3.3 0.1 0.3 0.0 0.0 0.0 37.3 0.9 0.2 0.0 0.0 2.0 0.7 0.0 0.0 6.8 8.9 0.1 0.0 0.0 10.6 0.1 0.3 0.7 0.2 0.0 1.0 0.3 0.3 0.4 4.3 1.8 6.0 0.0 0.0 0.2 3.1 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TSPAN2 "FLJ12082, TSN2, TSPAN-2" ENSG00000134198 "Tetraspanin 2" O60636 1 115048011-115089503 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 47.4;intestine: 55.4" "Cell type enhanced" "Detected in many" "Ductal cells: 35.3;Enteroendocrine cells: 39.4;NK-cells: 40.2;Prostatic glandular cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 109.0;neutrophil: 109.8" "Group enriched" "Detected in many" 4 "granulocytes: 109.8;NK-cells: 86.2" "Cell line enhanced" "Detected in many" "EFO-21: 58.8;hTERT-RPE1: 16.9;U-937: 26.9" "Region enhanced" "Detected in all" "white matter: 842.5" "Low region specificity" "Detected in many" "HPA015640, HPA073306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA015640: AB_1858405, HPA073306: " "unprognostic (4.56e-2)" "unprognostic (6.86e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (1.57e-3)" "unprognostic (1.64e-1)" "unprognostic (9.73e-6)" "unprognostic (6.06e-3)" "unprognostic (3.07e-2)" "unprognostic (4.74e-2)" "unprognostic (7.66e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.48e-7)" "unprognostic (5.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.48e-3)" "unprognostic (7.80e-3)" 7.2 1.8 3.5 10.1 1.9 20.8 4.5 0.9 1.4 10.7 1.3 55.4 5.4 47.4 7.5 14.6 22.2 7.4 7.4 1.0 3.6 8.4 0.8 6.5 1.4 5.4 4.1 2.9 2.9 10.2 2.1 3.0 5.7 15.4 12.0 2.0 3.0 28.3 2.8 2.0 11.0 42.7 2.1 3.8 13.8 1.1 5.7 2.7 2.7 5.2 1.1 24.7 8.0 1.2 15.1 0.3 1.2 0.0 0.0 0.2 0.1 2.1 1.0 2.4 3.8 3.1 9.5 0.0 58.8 3.5 3.3 2.2 1.9 0.0 2.7 3.1 1.2 0.5 1.1 0.0 0.2 0.1 0.0 0.0 0.4 0.7 0.0 16.9 0.1 11.1 0.0 0.9 0.0 0.8 8.2 1.3 13.8 3.2 1.6 0.1 0.8 0.0 0.4 5.8 3.0 4.5 3.5 1.6 0.2 8.2 0.3 0.6 0.2 0.2 5.7 0.4 14.1 12.5 0.4 0.1 0.1 26.9 6.9 109.0 9.1 55.8 17.4 0.2 5.6 0.6 20.5 22.6 4.1 0.3 3.4 17.0 109.8 86.2 0.1 3.8 3.3 13.1 3.5 1.9 0.9 1.4 1.0 3.6 5.4 4.1 5.7 2.1 5.7 1.2 18.7 0.0 0.6 0.3 1.4 8.0 23.2 10.9 1.8 2.5 1.5 7.6 9.6 0.0 4.4 11.0 0.0 1.4 19.9 0.1 0.0 35.3 12.2 14.3 0.9 16.3 39.4 3.0 2.8 2.4 4.3 4.0 0.5 16.3 0.0 2.0 6.4 0.0 0.7 0.0 5.4 1.3 4.1 0.6 3.7 4.6 0.6 3.0 3.6 2.8 2.7 0.0 40.2 1.5 0.2 10.9 0.0 3.0 3.3 30.0 0.0 1.3 10.7 0.4 6.6 1.4 16.2 0.1 0.9 0.2 2.7 0.3 17.2 0.1 1.4 21.6 TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.2;Fibroblasts: 168.7;Hofbauer cells: 240.6;Leydig cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" 129.1 37.1 15.8 29.6 14.7 11.8 102.0 17.9 18.7 90.9 44.1 60.3 13.7 84.2 9.2 26.1 85.8 54.1 57.6 15.6 17.4 60.8 37.6 101.4 46.3 17.1 16.7 91.3 32.5 17.6 24.2 61.6 15.6 52.9 10.5 2.5 34.2 33.7 25.7 56.3 43.3 27.5 15.5 85.0 37.0 16.8 18.2 13.2 79.9 22.9 12.7 66.8 71.8 12.9 30.7 238.7 40.8 73.6 61.2 121.4 27.5 153.0 182.5 118.4 81.3 49.5 37.5 2.3 60.4 221.3 68.2 11.3 14.5 145.6 22.2 20.4 17.4 32.5 75.7 71.6 201.4 10.4 38.9 211.5 26.1 42.8 129.0 116.1 78.5 12.5 13.5 184.5 115.8 64.6 7.0 13.0 52.3 39.2 172.7 24.2 29.1 55.4 138.3 2.0 48.0 28.6 75.8 83.6 162.1 17.4 118.5 7.7 116.0 134.2 53.4 27.3 52.2 10.2 1.5 4.5 138.5 11.1 121.8 0.1 146.4 0.1 7.4 143.5 4.6 6.9 3.7 7.2 101.2 5.4 6.2 11.7 3.4 95.6 39.9 7.0 3.6 65.2 15.8 14.7 17.9 18.7 15.6 17.4 17.1 16.7 15.6 15.5 18.2 12.9 194.2 105.8 68.5 6.5 5.6 47.5 22.2 78.8 13.6 9.5 19.4 38.6 9.5 74.4 24.6 31.3 4.2 39.5 8.1 1.7 7.9 82.6 2.1 5.9 43.2 117.3 0.0 12.0 0.6 16.7 31.9 168.7 5.6 10.8 37.2 62.8 97.5 28.2 240.6 13.5 2.9 2.6 4.1 109.9 71.5 7.3 172.7 70.3 147.7 11.2 19.2 43.8 8.2 2.5 0.3 61.3 0.3 95.2 9.3 15.7 0.3 34.7 5.8 6.7 59.2 23.9 67.5 4.7 31.5 6.1 32.8 16.8 10.2 44.7 1.1 6.1 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 951.1;stomach 1: 631.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1688.5;Ductal cells: 943.3;Intestinal goblet cells: 886.7;Paneth cells: 2225.8;Proximal enterocytes: 3546.1;Undifferentiated cells: 1583.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "OE19: 2160.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" 11.1 9.7 1.9 126.9 5.2 0.0 17.0 6.1 7.1 28.6 1.6 951.1 916.0 12.5 11.7 5.5 13.4 208.2 5.5 1.8 3.4 57.6 53.2 23.0 4.6 12.4 4.9 41.8 60.0 0.4 2.5 2.0 10.5 163.9 862.0 0.3 76.4 10.8 63.7 13.6 848.3 39.2 8.5 0.3 631.0 5.8 4.4 1.1 6.5 12.4 3.8 11.0 4.0 14.6 0.0 0.7 0.0 0.0 5.2 0.8 2.8 0.0 0.0 0.0 0.0 48.8 3.1 0.0 0.2 0.0 0.6 6.5 0.0 0.0 0.0 0.2 0.1 0.0 52.2 3.3 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.3 0.0 0.2 3.0 0.3 2160.7 173.3 0.2 0.0 4.9 34.1 41.0 4.1 7.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.3 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 6.1 7.1 1.8 3.4 12.4 4.9 10.5 8.5 4.4 14.6 0.8 0.0 2.2 0.0 6.1 20.8 32.5 14.0 0.6 0.3 8.5 1.8 0.3 346.0 76.7 44.1 0.0 1.2 0.0 1688.5 127.2 943.3 34.5 3.7 4.5 3.8 174.1 0.0 0.1 654.9 0.6 37.3 645.3 44.8 4.5 0.0 2.2 26.0 0.2 0.0 0.1 886.7 16.2 2.2 29.1 17.9 44.1 2.6 64.0 0.0 7.8 10.3 0.0 0.5 14.3 325.0 2225.8 32.0 2.2 376.2 3546.1 2.5 30.2 0.6 0.0 7.7 23.6 0.5 1.0 2.7 13.5 1.1 5.8 10.7 1583.9 46.0 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TSTD1 KAT ENSG00000215845 "Thiosulfate sulfurtransferase like domain containing 1" Q8NFU3 1 161037631-161038977 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 684.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 205.3;OE19: 215.1;SK-BR-3: 284.0;T-47d: 274.9;U-266/70: 315.4;U-266/84: 243.2" "Region enriched" "Detected in some" 4 "olfactory bulb: 6.6" "Low region specificity" "Detected in all" "HPA006518, HPA006655" Approved Approved "Cytosol,Cytoplasmic bodies" NA NA 57000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA006518: AB_2667608, HPA006655: AB_10600919" "unprognostic (6.10e-2)" "unprognostic (4.70e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" "unprognostic (5.77e-2)" "unprognostic (1.63e-1)" "unprognostic (6.56e-2)" "unprognostic (2.51e-3)" "unprognostic (2.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (4.64e-2)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (8.57e-3)" "unprognostic (8.88e-3)" 33.8 72.1 28.3 25.8 31.4 48.3 73.6 19.8 40.3 31.4 34.6 60.3 40.4 10.4 101.5 91.3 69.2 18.9 55.4 28.2 28.0 125.3 74.7 47.4 52.8 21.2 23.4 55.1 93.5 167.2 119.2 13.2 23.2 98.6 40.8 11.4 175.7 43.5 38.7 79.6 50.5 8.5 20.8 39.7 61.3 35.6 27.3 59.5 140.0 18.6 51.2 29.9 46.4 24.9 119.8 1.6 0.3 0.6 0.0 0.0 2.1 0.2 0.0 0.2 0.0 11.1 112.5 25.0 67.9 0.0 0.0 107.2 0.1 46.4 0.0 98.4 84.9 13.3 43.2 0.0 12.2 43.7 0.9 0.6 28.2 0.0 4.8 0.1 15.6 100.8 0.4 130.8 12.8 205.3 118.6 0.6 0.7 215.1 0.3 38.7 0.0 184.8 98.0 32.8 67.5 37.2 0.0 284.0 0.9 54.0 274.9 0.6 0.5 0.0 41.5 0.6 4.8 315.4 243.2 26.3 0.3 0.2 0.4 438.2 24.2 357.7 226.5 72.0 218.8 530.9 296.2 252.0 72.6 506.1 333.3 282.1 337.5 306.5 104.8 203.9 410.8 220.6 28.3 31.4 19.8 40.3 28.2 28.0 21.2 23.4 23.2 20.8 27.3 24.9 6.5 253.2 228.8 1.0 170.3 86.3 307.5 331.1 160.5 16.2 443.9 457.1 68.4 223.1 259.0 367.8 27.1 271.5 101.2 478.1 684.8 169.7 16.3 336.9 29.2 14.0 218.5 29.0 5.8 151.5 112.7 35.8 59.1 201.2 124.7 88.7 10.8 149.3 72.3 3.3 1.9 418.1 402.8 18.7 116.2 25.1 8.4 40.7 151.2 1.9 178.3 73.0 206.0 1.0 0.7 131.5 383.6 9.8 110.5 386.2 426.6 665.8 615.1 31.8 19.7 99.5 37.7 73.3 44.4 199.6 135.8 151.0 149.3 31.7 267.0 384.9 TTC23 "FLJ12572, HCC-8" ENSG00000103852 "Tetratricopeptide repeat domain 23" Q5W5X9 15 99136323-99251223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039806, HPA040369" Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA039806: AB_10793921, HPA040369: AB_10795381" "prognostic favorable (3.17e-4)" "unprognostic (5.41e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.40e-2)" "unprognostic (6.53e-2)" "unprognostic (9.25e-3)" "unprognostic (2.56e-1)" "unprognostic (6.18e-2)" "unprognostic (1.76e-3)" "unprognostic (1.88e-1)" "unprognostic (3.24e-1)" "unprognostic (3.21e-2)" "unprognostic (1.11e-2)" "unprognostic (4.31e-1)" "unprognostic (7.99e-2)" "unprognostic (1.23e-1)" 8.3 10.1 5.3 4.3 6.6 1.1 8.0 5.1 6.3 11.6 6.6 17.1 3.5 11.2 6.9 9.8 10.0 8.8 10.6 4.5 6.2 8.9 8.1 6.6 3.1 6.7 5.8 14.9 8.0 8.9 5.3 9.4 6.5 10.7 7.8 7.2 6.7 9.2 8.1 8.4 6.8 10.0 5.7 5.2 9.1 13.0 6.0 3.7 12.7 7.6 3.3 13.2 10.1 8.1 9.9 9.8 15.3 17.8 18.0 20.2 6.4 12.0 14.8 12.6 14.2 8.8 17.0 2.4 23.7 13.7 11.4 19.0 5.0 12.0 13.7 3.3 16.3 10.7 17.1 7.0 10.4 2.4 0.7 14.5 10.5 9.9 9.5 13.7 21.6 4.8 8.3 1.4 11.8 6.0 8.6 2.7 8.4 2.7 7.0 2.7 19.9 3.8 10.0 13.2 6.7 3.0 15.8 6.4 14.7 15.4 10.7 10.9 14.3 16.0 9.4 10.7 15.5 8.1 12.4 3.3 14.3 0.8 9.6 1.8 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.5 0.5 0.1 0.5 0.1 0.0 5.3 6.6 5.1 6.3 4.5 6.2 6.7 5.8 6.5 5.7 6.0 8.1 5.9 3.2 7.0 27.1 0.6 2.4 4.6 4.4 4.6 1.7 4.6 4.3 9.5 4.3 5.2 5.5 0.0 4.6 0.1 4.3 5.9 6.0 12.5 3.3 10.6 7.0 0.0 0.8 3.3 6.2 4.6 7.4 10.2 4.5 1.3 13.5 9.3 5.3 4.0 8.4 3.5 5.7 6.1 3.8 1.7 8.5 9.0 2.5 1.8 15.9 0.6 11.5 0.0 6.6 13.2 3.9 2.6 10.1 0.1 3.1 3.8 5.5 4.0 5.4 6.6 6.5 5.5 18.0 9.2 7.9 4.0 1.9 0.4 10.9 6.7 2.6 TTC24 ENSG00000187862 "Tetratricopeptide repeat domain 24" A2A3L6 1 156579723-156587719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 21.2" "Group enriched" "Detected in some" 5 "B-cells: 4.6;dendritic cells: 3.6;Erythroid cells: 1.3;NK-cells: 2.1;Skeletal myocytes: 1.7;T-cells: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NK-cell: 3.7;plasmacytoid DC: 12.4" "Group enriched" "Detected in many" 4 "dendritic cells: 12.4;NK-cells: 3.7" "Cell line enhanced" "Detected in some" "JURKAT: 10.3;MOLT-4: 3.8;REH: 11.9;U-698: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029799 Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029799: AB_10601684" "unprognostic (2.43e-3)" "unprognostic (5.61e-5)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-6)" "unprognostic (6.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.42e-1)" "unprognostic (7.96e-2)" "unprognostic (4.87e-9)" "unprognostic (1.07e-2)" "unprognostic (5.19e-2)" "unprognostic (2.22e-2)" "unprognostic (9.76e-4)" 0.1 0.0 0.0 1.9 0.1 1.8 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 5.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.2 0.2 0.0 0.0 3.0 0.4 0.1 0.0 21.2 0.1 0.0 5.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.1 0.0 3.8 0.7 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 1.1 0.1 1.7 0.2 1.8 0.2 3.7 0.0 12.4 0.0 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTC7B TTC7L1 ENSG00000165914 "Tetratricopeptide repeat domain 7B" Q86TV6 14 90524564-90816479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 88.8;Excitatory neurons: 116.7;Inhibitory neurons: 132.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.6;eosinophil: 8.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 72.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058363, HPA059577" Enhanced Supported "Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA058363: AB_2683692, HPA059577: AB_2684069" "unprognostic (9.37e-2)" "unprognostic (4.20e-2)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.58e-1)" "unprognostic (2.67e-4)" "unprognostic (9.42e-2)" "unprognostic (2.17e-1)" "unprognostic (5.38e-2)" "unprognostic (7.60e-2)" "unprognostic (2.75e-3)" "unprognostic (2.87e-2)" "prognostic favorable (3.20e-6)" "unprognostic (2.74e-2)" "unprognostic (7.41e-2)" "unprognostic (4.48e-2)" "unprognostic (1.07e-2)" 23.7 11.6 42.9 9.1 43.4 10.2 18.1 47.1 57.2 20.1 0.7 37.9 5.0 24.2 6.1 15.5 18.0 9.2 33.2 51.0 18.7 16.9 17.6 18.5 4.1 35.7 32.2 15.8 24.7 15.7 18.2 18.4 38.7 16.1 4.4 14.4 12.8 13.9 60.9 9.3 11.0 17.6 14.6 15.4 22.4 4.2 45.2 3.5 9.5 27.9 2.7 25.4 13.1 39.6 19.4 17.2 20.0 14.8 18.2 21.5 65.5 15.5 13.2 20.2 21.7 4.5 5.1 0.2 23.6 17.4 23.9 0.4 13.1 10.8 19.6 35.3 14.1 43.6 8.9 4.1 18.3 1.0 72.8 16.1 7.1 10.9 13.2 18.5 29.4 16.9 24.7 35.3 19.7 20.5 0.5 17.2 11.4 1.1 14.8 37.8 33.0 6.6 6.6 14.4 30.5 20.9 15.4 6.3 33.3 12.7 9.0 13.3 33.7 20.6 16.1 15.2 25.4 12.0 6.3 0.2 29.6 4.1 20.6 5.6 0.2 8.0 0.1 0.5 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.1 1.0 0.3 0.1 0.5 0.9 0.5 42.9 43.4 47.1 57.2 51.0 18.7 35.7 32.2 38.7 14.6 45.2 39.6 13.1 3.2 1.1 88.8 0.5 2.8 2.1 1.1 0.6 13.4 2.7 2.8 21.6 2.8 0.4 5.5 16.7 13.1 0.6 0.1 1.9 2.3 5.9 1.3 5.2 7.9 1.2 2.5 116.7 2.4 7.4 7.3 0.5 2.0 7.6 20.0 10.8 9.9 8.1 30.3 132.8 0.1 4.1 5.6 4.3 3.2 6.8 7.2 12.4 36.5 2.7 6.0 0.0 69.9 70.7 0.8 0.1 7.2 0.4 3.0 0.3 4.0 5.5 17.8 26.3 9.9 9.2 1.7 1.6 0.7 2.0 30.1 1.1 2.1 0.0 1.2 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 TUBA3D H2-ALPHA ENSG00000075886 "Tubulin alpha 3d" P0DPH8 2 131476119-131482934 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "heart muscle: 86.2;testis: 220.2" "Cell type enhanced" "Detected in some" "Early spermatids: 358.9;Late spermatids: 119.6;Spermatocytes: 667.9;Spermatogonia: 326.1" "Cancer enhanced" "Detected in many" "testis cancer: 7.6" "Region enhanced" "Detected in single" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.1" "Not detected" "Not detected" "CAB004972, HPA039247, HPA043684, HPA063394" Uncertain Supported Microtubules NA NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Microtubules "CAB004972: AB_425727, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic favorable (4.65e-4)" "unprognostic (6.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-3)" "unprognostic (1.82e-1)" "unprognostic (1.50e-3)" "unprognostic (2.17e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (2.89e-1)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (4.75e-9)" "unprognostic (4.60e-2)" "unprognostic (2.28e-1)" "unprognostic (9.96e-4)" "unprognostic (2.28e-1)" 0.1 0.1 0.4 0.2 0.3 0.4 0.6 1.6 0.4 2.8 0.0 0.1 0.1 4.8 6.8 0.2 4.0 0.2 86.2 0.6 0.2 0.1 0.4 0.1 0.4 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 10.1 0.0 0.3 0.3 0.4 0.1 0.6 0.2 0.3 0.0 0.2 0.2 220.2 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.5 0.2 0.2 0.9 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.7 0.1 0.6 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.3 0.0 0.5 0.5 1.1 0.7 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.5 0.1 0.2 0.0 0.0 0.2 0.1 0.0 0.2 0.3 0.4 0.5 0.3 0.1 0.2 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.6 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 36.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.9 0.4 1.1 1.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.1 0.0 0.4 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 119.6 12.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 4.8 0.0 0.0 0.0 0.0 52.6 0.0 0.1 667.9 326.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 80.3;Endometrial stromal cells: 61.1;Glandular and luminal cells: 206.7;Syncytiotrophoblasts: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 114.6" "Group enriched" "Detected in all" 5 "granulocytes: 114.6;monocytes: 47.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 12.5 9.4 4.8 16.0 6.4 22.6 18.7 5.9 10.0 12.8 10.9 12.1 11.0 9.1 8.9 24.7 8.8 11.3 8.2 5.1 7.9 7.5 38.4 16.5 19.1 9.0 6.3 8.7 13.1 8.7 8.2 14.3 7.8 20.8 11.8 7.7 14.2 7.2 13.6 33.7 12.3 7.8 5.1 20.6 13.6 11.6 9.2 15.1 8.6 9.3 19.2 13.4 16.0 9.0 16.2 17.2 9.8 14.3 22.4 36.0 12.2 21.6 20.5 9.1 10.6 7.8 13.7 22.8 18.9 14.0 9.5 27.3 11.8 12.0 13.5 27.1 6.0 16.5 18.4 13.7 19.3 19.1 21.8 23.5 22.7 14.5 16.2 13.7 15.0 12.3 15.9 24.0 24.6 14.9 16.0 11.0 7.5 25.1 11.1 8.0 17.5 10.1 15.3 31.4 7.2 5.7 13.1 15.5 7.4 11.6 6.4 7.8 24.8 8.7 10.5 15.7 14.8 27.4 23.3 16.5 20.7 10.8 11.8 35.4 19.4 20.5 15.0 24.7 12.5 11.6 8.2 10.7 11.9 12.2 9.5 10.1 114.6 12.8 47.8 5.5 8.8 8.9 4.8 6.4 5.9 10.0 5.1 7.9 9.0 6.3 7.8 5.1 9.2 9.0 28.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 34.2 16.4 0.0 0.0 0.0 9.2 0.0 22.4 36.6 0.0 5.9 29.6 0.0 80.3 61.1 7.2 0.0 0.0 0.0 17.9 17.4 5.6 0.0 206.7 0.0 36.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.0 12.4 0.0 0.0 0.0 0.0 27.8 0.0 0.0 13.8 0.0 0.0 6.7 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 92.5 14.8 30.9 0.0 0.0 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Plasma cells: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 141.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" 15.7 14.2 4.5 22.5 5.6 55.4 16.6 7.7 5.9 20.8 16.6 30.0 38.5 15.1 23.6 13.1 16.2 17.3 13.7 5.0 4.9 25.7 44.3 34.9 25.3 4.8 4.8 16.6 26.5 45.1 12.6 17.0 4.8 24.4 29.8 15.3 34.8 14.9 30.1 12.0 32.0 15.6 4.6 22.4 36.1 8.5 4.9 20.6 34.4 14.9 27.9 25.3 11.8 5.0 26.1 17.7 8.2 11.2 21.6 18.0 14.4 25.3 34.5 22.7 29.1 8.8 40.5 65.2 41.6 32.0 30.9 22.9 10.2 21.4 18.5 29.4 13.5 13.9 19.4 43.8 31.7 20.6 27.1 13.7 23.6 25.4 39.9 17.6 28.9 14.6 21.5 81.8 20.2 23.7 16.1 7.9 10.7 18.6 9.1 20.5 16.5 141.9 26.0 13.7 11.5 10.9 49.6 38.2 27.3 9.1 23.4 28.1 30.1 10.5 12.0 49.8 14.7 110.5 64.8 39.5 22.3 25.7 17.9 3.5 2.4 7.7 1.8 1.7 4.5 3.8 3.3 4.1 2.6 4.6 3.2 2.1 0.7 5.6 2.2 2.0 6.8 2.8 4.5 5.6 7.7 5.9 5.0 4.9 4.8 4.8 4.8 4.6 4.9 5.0 16.2 44.8 46.2 21.9 49.2 14.7 24.8 12.9 23.3 16.2 16.1 18.0 9.1 18.6 24.6 18.4 50.1 21.1 27.2 45.8 15.6 20.4 3.1 19.9 14.6 15.2 24.5 6.5 23.0 39.7 29.8 14.0 45.3 28.5 15.2 13.0 15.7 39.3 30.3 23.5 25.5 44.0 8.2 18.1 26.9 1.4 20.2 29.2 23.2 18.7 21.2 16.4 15.5 22.1 18.6 26.1 21.0 13.2 307.9 28.0 37.1 15.2 15.9 23.4 6.6 13.8 16.2 11.6 13.1 17.5 11.8 25.0 25.2 11.3 27.7 32.1 TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350307 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 459.7;Prostatic glandular cells: 557.4;Urothelial cells: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 1452.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm NA NA 6100000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: AB_2678709" "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" 47.1 148.1 22.5 40.6 21.1 64.7 28.0 20.9 22.6 28.0 37.3 50.9 58.4 47.9 21.0 30.7 39.0 55.9 65.8 21.1 29.8 37.9 46.5 63.0 34.4 55.2 26.7 34.1 19.0 33.8 21.2 39.1 33.3 41.0 45.6 20.1 20.8 60.6 67.8 12.4 39.4 51.6 22.9 27.8 52.1 37.8 24.6 42.8 30.4 64.0 34.1 141.6 30.1 25.7 228.4 1032.6 118.1 111.3 553.5 308.0 409.8 412.4 259.3 182.7 186.8 110.5 329.4 169.3 187.0 1452.6 682.1 77.7 235.7 158.6 214.1 82.7 101.8 143.1 765.8 468.0 885.7 226.3 149.9 176.9 159.8 403.7 128.1 557.1 634.0 227.9 200.5 77.5 276.8 109.1 233.4 102.7 114.4 453.0 1053.1 227.3 82.1 146.5 211.2 123.1 182.6 110.6 333.3 519.1 325.2 222.6 123.2 131.4 854.5 89.3 183.7 201.3 341.2 84.8 179.9 254.5 186.8 122.5 538.0 109.4 29.9 69.7 23.6 39.0 26.9 21.3 21.6 23.9 39.5 14.5 19.1 16.7 102.6 24.4 48.4 25.2 19.8 27.6 22.5 21.1 20.9 22.6 21.1 29.8 55.2 26.7 33.3 22.9 24.6 25.7 26.0 64.1 67.5 50.3 27.6 104.0 459.7 41.3 40.9 28.1 19.4 16.3 66.2 32.9 79.3 16.5 22.9 26.1 40.4 93.4 41.1 79.6 45.0 100.9 36.8 116.2 20.4 46.3 48.2 80.7 34.3 90.1 69.8 119.6 53.2 35.2 49.2 68.2 42.0 28.6 56.7 18.8 44.7 43.5 100.5 19.1 68.0 62.2 19.6 49.6 51.9 24.8 26.8 29.1 55.3 197.7 40.5 29.3 28.4 557.4 24.6 37.5 105.5 20.9 0.0 43.4 84.0 14.4 33.8 24.3 72.9 51.3 28.5 98.4 33.0 488.0 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.9;Erythroid cells: 3.8;T-cells: 20.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 7 "HEL: 23.0;JURKAT: 39.0;MOLT-4: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" 0.4 0.6 0.0 5.2 0.0 2.5 0.2 0.0 0.1 0.5 0.1 0.8 1.6 0.5 0.0 0.4 0.4 2.0 0.4 0.0 0.1 0.4 0.7 1.7 11.1 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.4 0.9 0.0 0.9 0.1 0.2 0.3 2.4 0.1 0.1 4.4 1.9 0.1 0.0 18.9 0.5 0.1 5.1 1.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 23.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.4 0.0 0.0 0.0 47.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.9 0.0 22.9 0.1 28.2 24.8 0.0 0.0 32.2 24.0 0.5 2.5 0.1 0.1 27.9 10.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.8 0.0 0.0 0.2 0.3 1.0 0.0 0.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 3.8 0.0 0.0 0.0 0.4 1.1 0.5 1.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.6 0.0 0.3 0.0 20.5 0.0 0.0 0.0 UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 76.1;Late spermatids: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" 13.5 11.4 7.6 8.7 9.0 1.6 17.5 24.7 9.5 24.6 8.7 15.0 18.4 21.0 9.3 10.6 12.0 16.1 10.3 7.9 8.4 15.6 15.7 13.2 9.2 8.4 8.2 21.1 12.5 11.1 7.0 17.1 8.3 13.4 15.8 9.2 11.9 12.7 9.8 9.9 22.1 17.9 7.9 7.2 12.2 35.4 7.8 12.0 11.5 15.7 10.2 14.5 11.3 8.3 21.9 16.7 78.1 61.0 48.1 42.9 38.0 27.8 33.2 29.9 43.8 36.5 15.9 18.7 23.5 43.6 51.4 15.1 41.7 30.3 40.1 18.0 30.3 5.7 17.6 28.4 32.6 13.3 10.3 33.1 37.1 31.9 25.7 25.8 36.5 28.8 2.3 7.5 28.6 23.8 23.7 27.8 33.4 19.0 21.1 43.5 38.0 7.2 36.3 23.0 22.9 57.9 30.1 27.0 28.4 39.9 23.3 21.7 26.6 39.6 29.2 21.0 23.9 6.8 19.9 17.8 13.9 18.2 31.0 0.0 0.3 0.0 0.2 0.4 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.2 0.7 0.5 0.1 7.6 9.0 24.7 9.5 7.9 8.4 8.4 8.2 8.3 7.9 7.8 8.3 15.2 6.4 4.8 14.0 3.7 22.0 25.7 12.8 15.9 8.4 22.2 12.1 5.5 11.5 11.9 9.2 0.0 9.8 5.6 22.8 17.6 14.5 76.1 9.7 28.3 12.3 8.9 0.0 14.9 12.0 21.7 31.4 8.6 23.6 0.0 14.2 13.9 15.1 6.8 25.2 22.5 12.2 14.2 6.5 44.5 130.9 24.8 9.8 14.2 9.4 5.8 16.2 1.0 25.6 19.8 21.6 9.8 21.1 2.9 29.8 20.5 17.2 6.8 3.4 6.6 16.7 19.6 5.8 9.7 17.0 18.8 8.1 4.0 11.9 13.7 39.6 UBXN10 "FLJ25429, UBXD3" ENSG00000162543 "UBX domain protein 10" Q96LJ8 1 20186096-20196050 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 49.7" "Group enriched" "Detected in many" 7 "Early spermatids: 117.5;Endometrial ciliated cells: 72.6;Late spermatids: 146.8;Respiratory ciliated cells: 117.8;Spermatocytes: 48.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.9;HMC-1: 7.1;K-562: 8.5;SCLC-21H: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028555, HPA028564" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "HPA028555: AB_10600417, HPA028564: AB_10601897" "unprognostic (3.00e-3)" "unprognostic (3.30e-2)" "unprognostic (4.31e-2)" "prognostic favorable (2.02e-4)" "prognostic unfavorable (2.23e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (2.37e-1)" "unprognostic (6.76e-2)" "unprognostic (4.60e-1)" "unprognostic (8.79e-2)" "unprognostic (5.78e-2)" "unprognostic (1.65e-3)" "unprognostic (7.11e-2)" "unprognostic (4.47e-2)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" 0.6 1.3 2.5 0.5 2.8 2.0 2.9 2.1 2.9 7.1 15.3 9.7 0.8 6.2 4.7 4.1 49.7 2.0 3.5 3.3 3.3 2.1 5.9 5.3 0.3 5.2 5.6 0.4 1.5 4.8 3.0 1.0 4.5 2.4 4.8 2.2 0.9 2.7 0.2 0.5 2.0 3.4 4.8 0.1 2.3 14.1 3.7 0.3 5.4 0.2 0.5 2.6 0.3 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 1.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 8.5 0.0 0.0 0.0 0.3 0.3 0.8 0.2 0.0 0.0 0.0 0.0 0.6 0.4 5.6 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 2.7 0.4 0.7 0.9 0.8 0.1 0.5 0.8 0.4 4.1 0.0 0.0 0.4 0.5 2.5 2.8 2.1 2.9 3.3 3.3 5.2 5.6 4.5 4.8 3.7 4.3 0.1 0.0 6.1 0.7 0.2 0.1 0.0 5.5 0.0 0.5 1.2 1.5 5.3 1.5 13.0 3.7 0.0 0.1 0.4 5.1 5.9 3.7 117.5 72.6 2.0 0.8 1.2 2.1 1.8 1.7 0.6 2.0 0.0 7.4 13.9 0.4 1.1 4.2 0.9 0.0 1.6 10.6 10.2 1.2 0.0 146.8 2.8 0.8 0.0 0.0 0.6 1.9 0.0 0.0 0.1 1.4 1.4 1.2 0.0 0.1 0.6 2.9 117.8 3.1 0.0 0.4 4.1 48.9 2.2 0.0 0.0 0.3 1.2 0.0 3.2 0.3 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 UNC5D "KIAA1777, Unc5h4" ENSG00000156687 "Unc-5 netrin receptor D" Q6UXZ4 8 35235475-35796550 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.8;intestine: 6.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 638.7;Inhibitory neurons: 768.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4;renal cancer: 1.0" "Group enriched" "Detected in many" 4 "hypothalamus: 19.8;thalamus: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;HeLa: 2.9;NTERA-2: 8.6;SH-SY5Y: 2.9;SuSa: 2.8;U-251 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042940 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042940: AB_10959525" "unprognostic (7.88e-2)" "unprognostic (1.28e-1)" "unprognostic (1.41e-2)" "unprognostic (2.29e-1)" "unprognostic (7.60e-2)" "unprognostic (1.87e-1)" "unprognostic (8.47e-2)" "unprognostic (3.82e-2)" "unprognostic (2.04e-1)" "unprognostic (4.13e-2)" "unprognostic (1.99e-1)" "unprognostic (4.48e-8)" "unprognostic (1.34e-1)" "unprognostic (9.15e-2)" "unprognostic (4.28e-1)" 0.0 1.7 1.7 0.0 2.4 0.0 0.0 0.0 3.1 2.3 0.0 0.3 6.0 1.7 0.0 0.0 0.1 0.0 0.0 2.4 19.8 2.1 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.1 3.3 0.0 0.0 4.8 0.5 4.9 0.0 0.2 0.0 0.0 1.9 0.9 0.0 0.0 0.1 0.7 7.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.5 0.2 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 0.0 3.1 2.4 19.8 0.4 1.6 0.0 0.0 7.0 0.0 0.0 0.0 0.0 129.6 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.7 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.1 0.1 0.0 0.0 638.7 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 40.4 768.3 0.7 0.0 0.0 0.0 4.4 0.0 0.0 0.0 42.2 0.0 1.8 0.0 43.2 10.2 0.0 0.0 0.0 0.0 1.8 2.0 0.6 0.0 2.6 0.0 0.0 0.7 0.7 1.2 0.1 0.1 0.0 0.0 0.0 2.6 0.0 UPK3A UPK3 ENSG00000100373 "Uroplakin 3A" O75631 22 45284949-45295874 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 21.3;skeletal muscle: 35.0;urinary bladder: 48.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 15.0;monocytes: 22.6;Prostatic glandular cells: 54.1;Proximal enterocytes: 29.8;Urothelial cells: 24.5" "Group enriched" "Detected in many" 6 "prostate cancer: 35.3;urothelial cancer: 78.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "myeloid DC: 86.6" "Group enriched" "Detected in many" 16 "dendritic cells: 86.6;monocytes: 32.0" "Group enriched" "Detected in some" 5 "Hep G2: 29.9;RT4: 48.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018407, HPA018415" Enhanced Uncertain "Nuclear membrane,Nuclear bodies" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nuclear membrane" "Nuclear bodies" "HPA018407: AB_1858641, HPA018415: AB_1858640" "unprognostic (1.27e-2)" "unprognostic (3.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (9.42e-2)" "unprognostic (3.98e-5)" "unprognostic (1.69e-2)" "unprognostic (4.82e-4)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-5)" "unprognostic (2.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (6.05e-3)" 0.2 0.1 0.1 0.5 0.1 1.5 0.2 0.1 0.4 0.0 0.3 1.0 0.0 0.1 0.1 0.3 0.3 0.9 0.1 0.1 0.2 0.1 0.0 0.2 0.9 0.2 0.1 0.1 0.2 4.9 0.7 0.0 0.2 21.3 0.7 0.0 2.8 0.2 35.0 0.0 1.3 0.1 0.1 1.1 0.1 0.1 0.1 0.7 2.3 4.5 0.8 48.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.5 0.0 4.6 0.0 0.1 0.0 0.2 0.0 48.9 0.1 0.0 0.2 0.8 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 21.2 0.0 0.0 25.8 0.0 1.2 0.0 0.1 86.6 0.5 0.0 0.0 3.6 0.4 32.0 32.9 0.0 7.4 0.1 0.1 0.1 0.4 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.0 0.0 0.7 1.2 0.1 15.0 0.1 0.0 0.1 4.6 3.6 0.2 2.8 0.1 0.0 0.0 0.0 4.0 3.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.1 3.5 0.0 4.8 8.7 1.7 0.3 6.4 0.0 0.0 22.6 0.8 2.1 0.0 0.0 0.0 9.3 0.0 0.1 54.1 29.8 0.0 0.1 0.0 0.0 1.6 0.5 0.0 0.4 0.0 0.4 0.1 0.2 0.0 4.4 24.5 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 250.1;Extravillous trophoblasts: 260.3;Macrophages: 199.5;Paneth cells: 260.8" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 362.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.4 9.4 3.8 7.5 4.4 12.5 10.0 3.0 5.8 16.8 2.0 9.8 4.3 3.9 0.8 66.9 5.7 5.9 8.9 3.1 3.9 39.8 11.9 18.8 3.7 4.2 2.8 1.9 4.6 5.0 7.4 3.8 3.7 4.9 5.3 0.5 14.2 1.1 3.7 3.1 6.5 3.4 1.3 20.3 4.1 2.2 4.4 1.2 8.0 0.9 6.6 9.1 31.2 3.7 19.5 26.0 2.4 5.2 8.9 4.0 29.7 7.9 15.5 14.5 17.5 10.8 9.9 0.0 2.5 9.7 89.9 13.9 5.2 46.1 9.4 4.1 4.5 0.8 4.8 4.6 7.4 0.9 1.3 5.0 21.8 6.4 362.8 5.9 9.1 0.4 1.5 13.5 7.6 2.3 0.0 2.9 9.4 4.2 20.7 0.0 4.8 6.0 33.7 11.5 2.3 1.6 10.2 3.0 63.4 29.3 2.4 0.9 12.4 29.6 22.9 7.3 22.6 21.4 34.7 3.7 29.6 3.0 77.8 11.5 16.0 12.2 11.8 12.1 8.9 0.2 7.8 8.7 6.5 0.6 8.1 8.1 6.2 5.4 14.8 0.5 8.4 10.9 3.8 4.4 3.0 5.8 3.1 3.9 4.2 2.8 3.7 1.3 4.4 3.7 107.4 19.2 58.5 5.2 19.1 46.8 26.3 104.4 19.4 27.6 9.0 16.1 11.6 24.3 51.0 11.0 33.3 15.1 122.9 250.1 70.5 50.5 1.0 42.1 22.4 108.1 13.1 4.4 16.5 40.5 260.3 34.1 5.1 91.1 25.9 3.8 72.5 17.5 110.0 16.8 29.4 35.0 85.5 130.5 118.1 2.4 5.3 199.5 87.2 1.0 61.4 13.3 71.1 4.0 3.6 117.9 260.8 2.2 30.3 30.4 42.8 23.3 11.9 29.2 6.6 21.1 32.2 0.3 9.5 42.9 29.8 78.7 71.0 1.5 29.1 34.9 UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" 7.5 12.2 7.4 3.7 7.5 5.7 7.5 8.2 9.7 7.6 9.3 9.9 8.1 6.5 1.7 12.3 6.1 1.2 10.2 7.1 7.1 10.7 11.9 4.7 4.2 7.6 7.3 6.5 9.0 3.5 6.7 2.2 7.7 9.4 1.9 3.9 11.5 3.3 15.7 9.0 8.3 1.5 7.0 7.4 9.6 3.4 7.4 2.4 6.3 5.0 1.6 6.3 8.1 8.1 26.9 52.9 7.7 12.0 4.7 4.6 6.5 10.4 3.5 7.7 7.6 31.4 22.8 17.4 21.1 3.6 10.4 26.1 7.4 12.3 2.4 8.8 27.4 9.8 28.7 20.3 6.3 16.0 7.6 4.4 10.3 6.8 7.6 4.8 6.0 8.1 21.3 12.2 4.3 82.4 15.7 39.2 8.6 10.6 29.8 17.9 11.7 31.1 6.1 13.2 15.5 15.7 11.5 41.7 16.2 2.4 39.7 14.9 7.9 16.8 19.7 17.6 23.6 18.7 11.0 18.3 13.8 13.7 12.3 14.6 25.0 20.1 21.3 19.1 20.4 30.8 21.1 19.0 20.0 29.9 19.2 15.3 11.0 19.6 17.2 26.7 25.8 20.0 7.4 7.5 8.2 9.7 7.1 7.1 7.6 7.3 7.7 7.0 7.4 8.1 49.0 44.8 25.0 3.6 32.3 0.0 42.2 0.0 47.3 21.8 77.5 86.4 35.8 70.1 16.1 64.4 16.7 53.1 22.9 65.2 140.8 56.6 1.7 50.3 40.6 32.9 35.2 32.2 2.4 78.4 53.1 32.4 54.6 41.1 5.1 28.0 44.6 125.4 54.8 18.5 4.2 75.2 0.0 39.7 0.0 3.7 48.4 29.2 0.0 7.5 47.2 59.7 66.9 5.0 5.2 67.4 66.9 36.1 38.4 85.1 209.3 170.6 12.4 37.0 39.5 28.3 31.8 4.2 32.0 91.0 0.0 29.0 25.3 35.1 79.0 57.0 USH1G "ANKS4A, FLJ33924, Sans" ENSG00000182040 "USH1 protein network component sans" Q495M9 17 74916083-74923256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 7.8;skin 1: 2.8" "Group enriched" "Detected in some" 5 "Early spermatids: 8.2;Late spermatids: 17.9;Muller glia cells: 11.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.8;hTCEpi: 1.6;K-562: 1.3;MCF7: 2.0;OE19: 1.9" "Region enriched" "Detected in single" 12 "olfactory bulb: 9.9" "Not detected" "Not detected" HPA024360 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA024360: AB_1858660" "unprognostic (2.95e-1)" "unprognostic (6.17e-2)" "unprognostic (6.34e-4)" "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.74e-1)" "unprognostic (5.59e-4)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (3.10e-4)" "unprognostic (1.57e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-2)" 0.0 0.9 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.3 0.0 0.0 0.1 0.8 1.9 7.8 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 0.0 2.8 0.2 0.5 0.0 0.0 0.0 1.8 0.6 0.1 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.8 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.2 0.1 0.3 0.1 0.1 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.3 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 2.3 0.4 0.0 0.0 1.7 0.6 0.0 0.2 0.0 0.0 0.1 0.2 0.4 1.6 0.3 0.3 0.0 0.1 0.0 0.1 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 37.9;Excitatory neurons: 35.5;Glandular and luminal cells: 52.5;Oligodendrocyte precursor cells: 73.4;Syncytiotrophoblasts: 73.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 11.7;SK-BR-3: 8.1;T-47d: 9.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762, HPA027763" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" "HPA023389: AB_1858691, HPA027762: AB_10603001, HPA027763: " "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.3 0.2 2.6 0.6 3.4 0.7 1.9 0.8 4.1 2.9 2.9 3.5 4.2 1.9 1.0 6.5 4.2 1.2 0.0 3.3 1.4 4.0 9.1 3.2 0.1 2.5 4.6 0.1 5.0 1.1 3.5 8.3 2.5 9.8 3.2 1.4 4.3 2.2 0.0 2.2 3.5 0.2 2.1 0.3 2.1 3.2 2.3 0.3 1.7 0.0 0.7 1.1 2.4 2.5 5.6 1.4 0.0 0.5 0.0 0.0 11.7 0.1 0.2 0.6 1.6 2.8 4.5 0.0 1.8 0.2 2.5 6.8 0.6 5.3 0.6 3.6 1.8 0.3 3.0 1.0 0.1 0.5 0.0 0.0 6.8 0.3 2.8 0.3 0.0 0.8 0.0 0.0 0.0 2.6 0.9 4.6 0.7 4.8 0.3 3.6 0.0 0.8 4.1 3.0 0.7 0.0 2.4 8.1 1.0 3.7 9.9 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 3.4 0.8 4.1 3.3 1.4 2.5 4.6 2.5 2.1 2.3 2.5 0.0 3.2 3.1 1.6 0.3 4.7 7.8 4.6 5.2 0.5 7.0 2.4 0.6 4.3 7.4 11.0 6.2 26.2 0.6 14.3 1.9 4.4 1.1 37.9 4.2 0.5 2.4 3.2 35.5 4.7 23.7 0.8 7.7 52.5 0.0 0.9 0.4 15.6 2.7 0.0 4.0 8.3 2.0 0.9 0.3 1.1 0.0 0.6 5.4 0.0 0.3 8.4 0.0 73.4 1.2 11.3 3.5 0.0 0.2 10.6 8.7 1.8 30.2 1.5 0.0 0.0 1.0 1.5 0.3 12.3 3.3 73.2 0.7 0.0 9.7 11.8 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 30.7;dendritic cells: 31.3;granulocytes: 34.9;Hofbauer cells: 50.6;Kupffer cells: 29.4;Macrophages: 33.9;Microglial cells: 30.9;T-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 100.7;Karpas-707: 114.7;MOLT-4: 115.8;REH: 76.1;THP-1: 88.9;U-266/84: 89.5;U-937: 95.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" 6.6 3.8 3.3 36.3 3.3 54.1 2.7 3.6 4.6 2.6 4.5 6.5 5.8 1.8 1.4 3.7 2.4 6.3 1.9 3.3 4.4 2.1 5.0 11.5 46.4 6.2 4.9 1.1 1.3 4.2 1.6 8.7 5.6 2.8 7.1 0.2 6.1 2.3 1.0 1.7 14.1 5.3 5.0 44.9 5.5 1.8 5.7 45.7 2.0 2.1 39.1 13.0 1.7 7.6 1.6 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 12.7 51.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 22.0 1.8 61.8 0.0 0.0 0.0 60.7 100.7 0.0 0.0 0.0 0.0 0.0 0.0 63.9 2.3 114.7 0.0 9.6 115.8 36.6 0.0 0.0 0.0 76.1 0.0 41.0 2.2 0.0 0.0 0.0 0.0 18.3 0.1 0.0 8.0 88.9 0.2 0.0 1.6 0.1 0.1 69.9 89.5 57.9 0.1 95.3 0.0 1.6 18.3 20.0 22.0 30.3 15.7 14.3 16.1 19.3 16.6 13.6 17.2 15.6 40.6 19.2 39.8 14.4 14.5 18.2 3.3 3.3 3.6 4.6 3.3 4.4 6.2 4.9 5.6 5.0 5.7 7.6 0.5 3.2 3.0 0.0 30.7 1.3 0.8 3.7 0.0 0.5 0.4 0.4 1.1 0.0 6.9 0.0 0.0 0.8 31.3 1.5 0.0 4.2 5.4 5.3 0.3 1.5 1.2 9.9 1.9 0.4 0.7 1.2 1.1 1.1 34.9 0.0 1.8 0.3 50.6 0.0 1.5 1.0 8.2 29.4 19.6 2.2 0.0 33.9 1.8 30.9 18.8 0.0 22.6 0.5 1.2 9.9 6.1 0.0 21.6 0.3 0.0 0.2 11.9 0.0 0.0 0.3 1.2 1.7 1.4 0.3 0.9 1.4 26.5 0.3 2.4 0.6 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 568.3;hTERT-RPE1: 547.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 750000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "CAB002453: AB_564057, HPA002131: AB_1080570, HPA063777: AB_2685121" "unprognostic (8.49e-2)" "unprognostic (1.61e-2)" "unprognostic (3.14e-1)" "unprognostic (6.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (4.02e-2)" "unprognostic (1.89e-1)" "unprognostic (1.37e-3)" 85.8 19.1 9.9 52.2 10.6 41.5 45.3 8.4 11.3 73.9 33.4 180.3 35.3 167.6 45.9 92.2 75.9 69.4 132.2 10.5 11.3 37.2 24.1 68.7 18.7 10.3 10.3 45.2 40.3 51.3 13.8 88.6 13.3 131.7 73.1 12.5 31.6 151.9 136.9 37.9 52.7 224.7 9.9 41.9 63.5 41.3 12.1 12.8 39.6 144.1 23.9 135.7 56.3 8.4 147.2 97.0 174.2 123.8 213.2 246.2 95.8 188.5 568.3 126.3 141.9 88.4 124.0 6.5 153.1 331.6 86.3 183.3 115.7 95.0 132.5 12.3 49.6 69.4 92.2 37.2 116.5 14.1 101.8 205.0 25.0 171.5 154.8 547.4 171.0 11.6 50.7 14.3 213.1 25.2 2.0 16.6 82.8 69.9 342.4 24.0 90.9 18.6 180.4 185.8 6.5 25.8 104.7 117.2 53.9 152.8 54.5 21.2 230.9 136.9 57.0 67.0 179.4 2.6 6.0 28.4 160.0 38.9 39.7 15.0 13.6 36.2 14.9 17.1 10.4 5.6 7.1 7.8 20.7 2.3 2.6 5.3 11.2 4.4 19.0 8.0 1.9 28.3 9.9 10.6 8.4 11.3 10.5 11.3 10.3 10.3 13.3 9.9 12.1 8.4 68.0 99.3 39.7 56.5 13.4 114.7 161.4 68.4 30.7 13.4 39.4 58.5 339.5 37.1 79.8 42.3 85.5 51.5 46.7 91.2 3.9 60.8 5.0 98.2 152.6 60.4 38.3 5.9 63.2 61.6 78.6 74.4 66.3 149.1 35.4 45.5 56.7 34.4 23.6 16.8 47.5 44.5 22.4 31.9 51.0 7.5 50.1 77.9 26.6 55.3 44.7 9.7 61.8 18.6 4.6 125.5 48.3 76.8 8.0 100.1 13.7 14.8 37.7 34.5 105.2 49.6 179.9 18.6 13.7 45.6 93.1 39.7 18.3 44.5 48.7 94.8 VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 385.2;skeletal muscle: 914.4;tongue: 942.7" "Cell type enhanced" "Detected in all" "Spermatocytes: 403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026864: AB_1858733" "unprognostic (2.55e-2)" "unprognostic (1.96e-2)" "unprognostic (9.88e-3)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-1)" "unprognostic (4.98e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.74e-1)" "unprognostic (1.19e-2)" "unprognostic (6.16e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (8.78e-3)" "unprognostic (6.94e-3)" 67.5 76.2 117.3 59.1 119.4 92.1 70.3 116.8 150.6 53.7 115.4 106.9 79.8 63.5 68.6 99.9 85.8 56.0 385.2 121.1 130.8 108.8 92.9 51.9 66.3 122.7 119.3 61.6 64.6 92.4 58.9 63.9 139.2 69.5 106.4 123.1 61.6 81.3 914.4 54.1 73.0 92.8 114.1 67.3 72.1 114.5 118.6 80.1 83.3 942.7 79.3 78.9 59.8 113.8 226.3 225.7 174.5 185.9 146.3 126.6 84.8 180.0 151.1 225.4 205.2 173.4 190.4 235.8 165.0 153.7 196.3 142.5 238.4 194.1 244.7 117.2 196.6 352.9 138.4 250.2 105.2 172.0 190.1 98.6 143.3 171.6 80.9 149.6 279.8 201.3 284.4 158.6 235.7 126.4 373.3 197.1 205.2 285.6 144.5 193.6 322.1 165.3 245.7 198.8 156.8 133.3 112.1 132.8 116.1 126.4 279.9 129.9 149.8 86.6 150.0 217.7 174.0 145.2 264.1 266.9 117.5 238.0 150.9 142.8 165.3 183.4 145.8 167.2 148.7 126.5 155.6 146.5 222.7 96.6 152.7 147.7 82.8 125.8 155.6 163.0 202.5 360.5 117.3 119.4 116.8 150.6 121.1 130.8 122.7 119.3 139.2 114.1 118.6 113.8 78.1 44.8 24.4 50.6 59.8 64.5 81.1 197.8 58.1 85.9 53.0 73.9 321.2 55.8 82.8 66.2 35.5 145.5 91.9 65.7 307.2 116.3 151.1 112.8 56.7 70.5 47.8 186.4 63.2 90.0 112.1 81.5 41.3 47.1 55.2 100.6 68.2 60.4 139.7 138.0 78.9 86.1 177.0 58.5 77.8 146.4 69.3 107.7 72.9 26.2 130.1 72.9 83.4 38.2 34.7 84.9 86.7 97.4 75.9 48.9 125.3 177.5 142.1 94.5 65.7 146.4 123.8 403.7 156.3 82.3 70.8 58.3 79.7 94.2 124.8 70.4 VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 235.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 141.7;Proximal enterocytes: 88.7;Undifferentiated cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.5;monocytes: 6.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 55.5;HDLM-2: 80.0;U-937: 85.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 4.3" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" 3.6 13.7 0.2 13.3 0.2 8.2 11.3 0.2 0.4 5.0 0.9 40.4 56.0 1.6 0.4 13.6 1.8 8.5 1.2 0.2 0.7 21.0 1.1 7.7 5.3 0.7 0.4 0.5 2.1 235.9 11.1 2.9 0.6 1.9 35.3 0.2 6.1 1.8 2.8 22.1 55.0 3.8 0.1 2.6 7.4 1.0 1.4 1.5 2.2 0.6 7.2 10.4 7.6 0.3 15.0 2.6 0.1 0.1 12.0 16.4 0.2 17.7 8.6 15.0 12.9 10.6 12.1 3.5 17.4 13.6 10.7 27.1 0.5 55.5 6.4 80.0 4.0 6.3 3.1 0.9 8.1 12.2 20.3 23.6 30.5 16.4 26.0 22.3 1.2 1.3 1.8 3.9 7.0 9.2 0.3 6.0 0.2 34.8 19.1 0.3 0.0 9.9 13.3 13.5 6.2 0.2 14.7 42.6 5.9 0.1 47.6 6.7 1.0 28.8 7.3 8.2 10.2 2.2 0.1 3.0 8.6 85.3 7.7 0.1 3.5 1.9 0.0 6.5 0.1 0.5 0.3 0.0 5.1 0.0 0.1 0.0 6.5 0.2 6.7 0.4 0.7 1.5 0.2 0.2 0.2 0.4 0.2 0.7 0.7 0.4 0.6 0.1 1.4 0.3 0.4 12.8 20.1 0.3 1.4 36.1 9.0 8.5 24.5 0.5 21.2 13.7 1.7 0.0 9.2 7.3 0.0 0.2 0.9 141.7 7.9 3.5 0.2 11.9 0.5 1.3 21.7 0.0 0.4 10.9 0.1 5.3 14.3 4.7 7.0 0.2 0.0 0.3 3.4 0.0 0.3 32.8 2.0 7.3 43.4 0.0 0.0 21.2 8.8 1.0 10.4 0.2 0.0 0.5 0.1 22.4 43.3 0.4 10.9 8.3 88.7 32.0 9.0 0.2 0.0 1.1 2.2 0.7 0.3 23.4 40.6 0.3 2.8 0.0 72.4 11.6 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4879.0;Langerhans cells: 4893.1;Leydig cells: 5013.2;Muller glia cells: 8977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 18287.8;fHDF/TERT166: 10084.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" 3467.6 423.1 349.3 610.6 369.5 1455.5 2362.8 289.1 527.4 1816.3 568.1 923.2 218.4 1226.5 400.0 451.5 1458.7 960.2 1364.3 337.5 404.6 473.6 192.8 1133.2 806.2 667.4 328.2 3690.8 370.0 224.8 574.5 1030.0 443.7 570.0 400.8 731.0 628.5 551.8 363.7 1126.8 674.7 1109.3 414.6 819.9 522.8 251.7 472.7 412.2 1391.1 555.8 744.7 983.5 1366.6 425.5 21.2 1119.0 1981.0 3180.7 6407.4 18287.8 3.0 5238.5 3458.9 3859.2 3421.5 8.5 70.4 2.9 273.2 10084.4 1804.7 8.4 283.8 147.0 3734.1 3567.5 387.2 563.2 523.5 0.3 1967.3 301.1 222.8 6746.8 6.5 5712.0 3213.4 9020.8 6366.3 372.4 889.3 1575.4 6939.5 4.5 736.6 911.2 632.4 1.4 1394.0 564.8 2745.9 95.7 3925.3 0.8 8.1 946.6 1.4 6.9 5447.5 1133.1 8.6 341.8 5459.0 3819.8 1644.5 3244.7 6311.5 1754.4 953.7 130.4 5775.4 28.9 3726.3 667.8 751.8 215.2 219.5 469.3 278.7 176.3 357.0 285.0 866.0 117.5 217.1 217.2 409.3 99.2 471.2 342.3 481.5 615.4 349.3 369.5 289.1 527.4 337.5 404.6 667.4 328.2 443.7 414.6 472.7 425.5 3211.7 157.0 349.4 53.5 605.8 725.8 21.6 361.2 58.1 74.2 108.8 539.1 109.5 94.4 157.3 108.5 50.1 22.1 1110.1 9.1 5.9 198.8 58.1 922.9 2314.1 2923.2 309.1 236.5 0.4 569.0 45.8 3443.0 101.4 693.7 2776.4 4879.0 2195.6 19.2 3541.4 33.7 0.3 1.8 16.2 2841.2 4893.1 131.6 5013.2 3177.8 3082.5 85.3 3893.1 8977.0 259.5 1.0 0.4 525.9 1.5 2336.6 2097.2 79.5 3.1 181.6 90.7 284.1 1420.0 3171.9 3714.2 55.1 27.5 39.4 473.0 52.7 1566.3 1791.1 6.2 28.9 VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 132.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.8;Intestinal goblet cells: 48.6;Paneth cells: 96.2;Proximal enterocytes: 58.6" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 60.8;OE19: 36.2;RT4: 44.0;SK-BR-3: 24.7;WM-115: 79.0" "Group enriched" "Detected in many" 4 "amygdala: 6.3;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" 17.5 2.6 10.1 3.4 12.7 2.3 16.9 13.5 15.2 2.9 5.1 28.0 34.5 1.2 6.6 5.3 1.3 6.0 6.5 13.0 5.5 2.7 32.4 132.1 4.6 5.3 4.8 0.6 2.5 4.2 1.9 2.8 6.3 25.0 27.7 4.2 22.7 8.9 1.2 29.8 30.0 1.3 4.4 5.7 6.1 1.4 4.7 1.9 15.1 4.9 2.4 8.7 5.0 12.1 0.1 2.4 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.4 2.2 60.8 0.2 3.1 0.0 0.0 2.4 0.0 1.6 0.1 0.0 5.2 3.8 1.8 0.0 0.3 0.0 0.5 0.0 3.8 0.2 1.2 0.0 0.7 0.6 0.0 0.0 0.0 5.2 0.0 0.3 3.8 36.2 0.2 0.5 0.0 2.8 0.0 44.0 1.3 0.0 0.0 24.7 0.0 7.1 15.2 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 79.0 0.0 1.8 0.0 0.2 1.5 1.0 0.0 2.4 1.0 2.1 0.0 2.7 0.8 0.0 0.0 1.3 0.0 0.4 0.9 10.1 12.7 13.5 15.2 13.0 5.5 5.3 4.8 6.3 4.4 4.7 12.1 16.0 3.2 6.0 3.3 1.3 7.6 4.5 2.2 22.2 0.2 19.2 21.5 2.6 5.7 2.1 1.8 8.4 0.1 0.4 71.8 0.0 0.3 3.0 0.2 0.1 2.8 4.8 0.0 26.9 0.9 1.0 1.0 16.3 0.6 0.0 0.3 19.6 0.4 0.7 0.0 1.5 48.6 0.0 8.7 4.0 0.6 0.0 5.9 0.0 3.7 8.9 1.4 0.0 3.0 1.7 1.2 96.2 0.0 1.5 6.3 58.6 0.1 1.0 5.4 32.9 0.2 20.8 0.1 0.1 4.1 7.7 0.3 2.9 0.1 24.0 3.9 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946056-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "skin 1: 18.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 11.9;Breast myoepithelial cells: 6.7" "Region enhanced" "Detected in single" "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 35: Glandular cells - Unknown function" 0.2 0.0 0.1 0.0 0.2 0.0 1.8 3.2 0.8 0.8 0.0 0.0 0.0 0.3 0.0 0.8 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 18.6 0.0 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.2 0.8 0.3 0.1 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 6.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.8;Early spermatids: 9.6;Gastric mucus-secreting cells: 5.1;Late spermatids: 15.8;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 5.7;HaCaT: 3.0;SCLC-21H: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" 0.5 0.0 2.7 0.4 1.6 0.5 3.1 2.2 1.6 4.0 0.3 1.3 1.6 0.9 1.0 1.2 6.4 0.2 0.0 1.4 1.3 0.5 0.0 3.3 0.2 1.9 1.7 0.1 2.3 0.2 0.3 0.4 1.8 5.4 1.0 0.3 4.5 1.0 0.3 6.4 1.4 0.1 1.7 1.4 8.4 1.1 2.1 3.4 0.8 0.2 0.5 0.7 0.9 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.3 0.0 0.0 3.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.6 0.0 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.7 1.6 2.2 1.6 1.4 1.3 1.9 1.7 1.8 1.7 2.1 1.5 0.4 0.0 0.0 0.0 0.0 0.3 4.1 2.8 6.8 0.0 1.1 0.3 0.5 0.0 1.7 1.8 0.0 1.3 0.0 0.1 0.0 2.1 9.6 0.7 0.1 0.2 0.0 0.0 4.1 1.6 0.0 0.1 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.4 2.0 0.0 0.0 15.8 0.3 0.0 0.0 16.9 0.0 0.0 0.0 2.5 0.1 2.2 0.2 0.0 0.0 2.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.8 0.3 1.1 0.0 0.7 0.0 0.1 0.5 1.3 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WDR93 "C1d-87, CFAP297, FAP297" ENSG00000140527 "WD repeat domain 93" Q6P2C0 15 89690811-89743638 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.9;testis: 11.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Early spermatids: 49.1;Endometrial ciliated cells: 28.1;Late spermatids: 42.4;Respiratory ciliated cells: 47.7;Spermatocytes: 30.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA046196, HPA048112" Uncertain Uncertain "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA046196: AB_2679582, HPA048112: AB_2680267" "unprognostic (2.56e-3)" "unprognostic (3.21e-3)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.90e-2)" "unprognostic (3.01e-1)" "unprognostic (1.15e-2)" "unprognostic (2.08e-2)" "unprognostic (1.22e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.40e-2)" "unprognostic (4.73e-2)" "unprognostic (9.84e-2)" "unprognostic (4.44e-2)" 0.4 0.2 0.6 0.0 0.6 0.4 0.7 1.6 0.6 0.6 3.5 0.1 0.0 0.4 4.9 0.0 8.9 0.2 1.2 0.8 1.0 1.0 0.1 1.0 0.2 2.4 2.9 0.4 0.6 0.5 0.8 0.1 1.1 0.6 0.1 2.8 0.3 0.5 0.3 0.2 0.1 0.0 1.6 0.1 0.1 11.6 0.9 0.1 1.8 0.0 0.1 0.0 0.0 1.0 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.2 0.7 0.2 1.0 0.1 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.6 0.6 1.6 0.6 0.8 1.0 2.4 2.9 1.1 1.6 0.9 1.0 0.1 3.2 0.5 2.9 0.0 0.3 0.7 1.8 0.0 2.7 0.8 0.6 0.5 0.0 4.2 9.2 20.9 0.4 0.1 0.1 3.9 0.8 49.1 28.1 0.6 0.7 0.0 0.0 2.7 0.2 0.3 0.4 0.0 0.8 0.0 0.4 0.4 0.0 0.2 3.3 2.1 0.1 0.0 0.3 0.8 42.4 1.5 0.3 1.8 0.0 0.6 0.6 0.0 0.5 1.0 0.3 1.1 0.7 0.1 0.7 0.0 2.1 47.7 14.8 0.0 0.9 0.6 30.4 5.7 0.0 0.1 0.3 0.6 2.9 0.2 0.4 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0 WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Extravillous trophoblasts: 120.2;Granulosa cells: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 100.4;Hep G2: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "HPA029128: AB_10603460" "unprognostic (4.27e-2)" "unprognostic (5.05e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.13e-6)" "unprognostic (7.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-2)" "unprognostic (6.97e-3)" "unprognostic (2.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.36e-3)" "unprognostic (5.33e-3)" "unprognostic (6.20e-2)" "unprognostic (5.02e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (3.64e-2)" 39.4 20.2 43.7 6.8 71.2 0.7 36.0 34.3 47.2 51.9 34.5 44.8 12.2 75.4 14.0 11.3 58.6 12.4 64.3 35.9 36.8 16.8 17.1 43.8 5.9 34.4 43.7 87.1 20.1 7.2 50.2 16.6 36.6 34.6 3.4 6.9 14.6 36.3 16.0 26.8 22.0 17.0 33.7 29.3 29.1 31.8 44.1 2.9 48.1 7.5 2.3 57.8 29.1 32.1 14.1 35.3 9.1 33.9 37.2 10.2 100.4 23.0 32.7 15.8 14.6 24.8 37.2 5.5 34.3 26.3 74.8 8.0 6.8 14.2 6.4 5.7 14.1 0.0 11.0 83.0 34.5 0.0 1.1 33.7 18.8 15.0 13.6 12.3 25.3 2.5 0.6 24.3 9.7 28.0 1.1 0.3 13.5 20.3 38.0 3.4 9.6 7.5 6.7 52.4 6.1 15.4 12.2 17.4 13.1 9.6 31.5 0.3 19.9 19.8 22.8 19.1 14.8 26.0 10.1 0.5 23.9 0.2 18.3 0.0 0.7 0.0 2.7 0.9 3.9 2.4 1.3 2.1 0.2 1.2 1.3 1.5 0.0 1.5 1.1 0.4 0.8 1.4 43.7 71.2 34.3 47.2 35.9 36.8 34.4 43.7 36.6 33.7 44.1 32.1 38.4 131.4 12.4 40.5 3.6 2.4 1.9 2.5 2.2 4.9 9.7 6.0 42.5 5.7 5.7 25.8 0.0 22.2 1.0 2.0 0.0 5.5 10.3 18.1 12.6 21.1 33.5 0.0 2.7 4.4 120.2 15.4 13.3 25.5 1.3 71.4 21.4 10.7 19.0 3.3 4.7 5.7 4.1 1.3 2.4 19.1 40.0 2.5 12.4 12.2 0.7 31.7 0.0 9.5 2.4 10.9 1.6 57.9 19.0 4.7 3.7 3.7 12.1 5.0 13.1 3.6 15.1 10.8 14.6 2.2 3.4 39.7 1.6 11.0 4.7 2.1 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 160.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 32.6;K-562: 36.8;TIME: 34.1;WM-115: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.3 0.0 0.7 1.1 0.9 0.0 2.8 0.8 3.3 0.6 0.3 9.8 1.9 0.2 0.7 8.9 0.4 0.0 0.1 1.7 1.1 37.6 0.2 0.1 0.1 1.1 0.7 4.3 0.2 0.0 1.2 0.0 0.7 11.6 11.0 0.6 1.8 1.1 0.0 0.5 3.7 0.4 0.6 0.1 3.4 0.2 1.0 0.0 0.0 0.3 0.1 0.2 0.4 1.0 2.1 1.2 0.6 0.0 0.7 0.2 4.8 11.9 4.8 4.5 1.3 0.7 1.0 0.6 6.8 32.6 1.2 0.0 0.2 0.3 8.6 0.6 1.8 0.1 0.0 4.7 7.4 0.3 0.7 3.9 1.4 6.4 2.1 2.1 0.3 0.4 36.8 1.3 0.0 1.0 0.0 1.1 0.3 2.0 8.2 0.6 1.2 0.0 0.0 0.5 0.0 0.2 0.1 0.2 1.7 4.1 2.4 2.7 34.1 0.3 3.1 0.5 0.4 6.2 5.3 1.2 0.0 2.1 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.8 3.3 1.7 1.1 1.1 0.7 0.7 0.6 1.0 1.0 0.2 0.0 0.6 0.0 0.5 0.0 0.2 0.0 0.6 0.2 7.1 4.1 1.0 1.5 0.6 7.3 0.0 0.0 0.3 8.0 160.4 0.0 0.0 5.1 1.1 0.2 13.1 0.0 0.2 0.2 0.2 0.1 3.1 6.7 4.5 0.1 0.7 0.0 0.0 0.0 0.2 40.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.4 0.0 3.6 0.9 1.0 2.9 0.5 0.0 0.2 0.5 0.8 0.8 12.1 0.4 0.0 0.2 0.0 13.1 0.3 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.1;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.0 0.0 0.8 0.5 4.5 1.1 0.0 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.7 0.2 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.3 0.7 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.1 0.1 2.0 2.9 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.2 0.5 0.8 4.5 0.0 2.1 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.2" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.3;JURKAT: 3.1;RPMI-8226: 1.0;SCLC-21H: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" 0.0 0.8 0.1 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.4 1.2 0.1 0.0 0.0 0.2 0.0 0.9 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.0 0.7 1.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 73.4;Late spermatids: 99.6;Oligodendrocyte precursor cells: 110.1" "Cancer enriched" "Detected in many" 4 "glioma: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 40.0;HUVEC TERT2: 24.7;OE19: 26.4;PC-3: 24.8;RH-30: 50.5;SCLC-21H: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015919: AB_2216211" "unprognostic (1.50e-1)" "unprognostic (7.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.15e-2)" "unprognostic (2.61e-1)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-1)" "unprognostic (3.46e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" 2.2 2.2 19.7 1.0 21.7 0.0 1.8 29.5 19.8 1.1 6.8 6.8 3.4 1.2 0.2 0.6 1.0 0.9 2.0 18.1 19.1 5.9 0.5 1.4 1.3 29.4 23.8 0.5 1.5 0.9 3.5 4.8 24.9 0.6 3.8 5.7 1.2 0.7 11.4 1.3 4.3 1.3 22.2 13.6 1.3 11.2 22.9 1.1 0.9 3.8 0.9 0.8 0.8 26.7 0.0 5.8 40.0 3.2 0.2 0.0 2.1 4.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 10.0 0.3 0.0 0.0 13.6 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.5 0.0 24.7 0.1 0.0 0.9 1.2 0.8 0.0 0.0 13.3 26.4 24.8 0.0 50.5 1.6 8.4 2.1 15.5 0.0 0.2 0.0 0.0 4.1 0.0 0.3 0.1 0.0 1.4 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 21.7 29.5 19.8 18.1 19.1 29.4 23.8 24.9 22.2 22.9 26.7 7.7 0.0 0.0 11.8 0.1 0.4 0.0 0.0 0.6 24.1 0.2 0.1 3.8 0.0 0.0 1.8 0.0 0.7 0.1 22.4 1.9 0.3 73.4 0.1 0.0 5.9 0.0 0.0 2.7 0.2 0.1 0.2 0.0 0.0 0.0 0.7 10.0 0.4 1.2 1.7 12.5 3.3 0.0 0.8 0.4 99.6 0.6 0.0 1.8 4.7 0.0 9.8 0.0 110.1 20.6 0.2 6.5 0.0 0.0 0.0 21.5 1.4 0.0 3.5 0.0 6.0 0.7 0.4 3.3 0.1 0.6 0.0 0.3 0.1 5.8 0.1 WSCD2 KIAA0789 ENSG00000075035 "WSC domain containing 2" Q2TBF2 12 108129288-108250537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.7;thyroid gland: 16.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.7;Excitatory neurons: 30.1;Horizontal cells: 21.9;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 9.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "RT4: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013346, HPA048133" Approved Uncertain Nucleoplasm "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA013346: AB_1858865, HPA048133: AB_2797236" "unprognostic (1.50e-1)" "unprognostic (1.64e-3)" "unprognostic (1.50e-2)" "unprognostic (4.27e-3)" "unprognostic (1.68e-1)" "unprognostic (3.43e-1)" "unprognostic (1.80e-2)" "unprognostic (3.43e-3)" "unprognostic (3.03e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-1)" "unprognostic (7.43e-2)" "unprognostic (5.99e-2)" "unprognostic (3.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.32e-3)" "unprognostic (7.62e-3)" 0.9 0.7 8.9 0.1 14.3 0.0 0.8 36.7 13.9 3.5 0.3 3.3 0.3 10.1 2.1 1.0 2.6 0.1 0.4 17.9 4.2 1.0 0.0 0.3 0.1 0.6 2.4 0.3 1.4 0.0 1.4 0.2 2.2 4.2 0.3 11.9 0.3 13.5 0.2 0.8 0.7 6.8 2.7 0.1 1.9 0.2 10.0 0.0 16.8 0.4 0.1 2.5 1.3 7.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.9 14.3 36.7 13.9 17.9 4.2 0.6 2.4 2.2 2.7 10.0 7.2 0.8 0.0 0.0 5.9 0.6 0.1 0.0 0.1 0.0 43.7 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 30.1 0.0 0.0 1.6 3.1 0.0 0.0 0.0 0.7 0.0 0.0 21.9 27.7 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 2.8 0.0 0.3 0.0 9.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.2;Cone photoreceptor cells: 91.8;Endometrial ciliated cells: 81.8;Glandular and luminal cells: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 120.2;RPTEC TERT1: 260.4;SK-BR-3: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" 7.8 0.6 41.8 2.9 43.3 0.1 21.2 41.0 39.7 6.0 50.4 6.4 24.3 2.8 6.8 22.9 17.2 8.7 1.6 40.3 41.3 73.3 38.1 20.2 3.0 56.8 47.0 0.8 28.3 23.5 7.8 10.2 43.6 16.4 6.1 17.8 142.3 11.8 0.0 19.9 20.2 1.1 46.6 0.7 22.9 1.7 54.3 1.3 29.7 0.0 6.9 9.3 10.1 38.6 50.6 56.4 9.2 0.4 0.0 0.0 96.8 3.7 0.9 17.1 15.3 120.2 73.6 0.0 58.6 1.2 47.4 35.0 18.9 46.1 20.1 0.1 18.6 0.0 28.6 29.9 0.9 4.4 0.0 6.0 13.9 32.3 28.5 13.2 0.0 3.0 0.0 7.2 1.3 56.4 0.0 0.1 13.3 60.8 8.2 0.0 0.4 29.1 260.4 68.8 30.7 11.4 66.5 136.4 17.1 11.6 67.8 4.3 0.0 3.0 34.2 0.4 36.9 0.8 0.4 0.2 3.4 0.1 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.8 43.3 41.0 39.7 40.3 41.3 56.8 47.0 43.6 46.6 54.3 38.6 0.3 64.1 72.3 162.2 1.3 11.9 14.7 6.0 1.8 1.4 35.7 25.7 1.8 34.3 42.1 58.8 91.8 11.6 0.6 17.9 13.7 44.9 0.4 81.8 10.8 1.3 7.8 0.0 50.1 40.5 2.3 5.3 15.3 149.2 1.3 5.6 1.1 16.9 1.3 0.0 27.9 7.8 6.1 0.6 1.1 0.1 1.2 4.2 10.6 8.4 1.1 18.1 0.0 17.6 1.9 73.1 10.9 0.7 0.1 38.8 18.9 61.8 36.7 9.1 0.0 0.2 5.6 0.3 5.0 7.3 13.9 18.2 2.1 2.5 12.2 16.5 XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 185.3;T-cells: 213.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 4.1;SCLC-21H: 3.3;SuSa: 6.1;U-266/70: 5.0;U-266/84: 1.9" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" 0.5 0.1 0.1 1.0 0.1 3.5 1.0 0.0 0.2 1.0 0.0 0.7 1.0 2.2 0.8 0.2 0.6 1.1 0.5 0.1 0.2 0.5 2.6 1.8 2.3 0.1 0.1 0.2 0.5 0.0 0.1 2.2 0.2 0.4 1.0 0.0 1.5 0.3 0.1 0.1 1.5 0.3 0.1 4.6 1.2 0.2 0.6 4.1 0.3 0.0 1.6 0.9 0.4 0.1 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.3 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.0 1.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 6.2 0.0 0.2 0.0 1.0 5.9 0.0 0.0 0.3 4.0 0.3 88.5 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.6 0.1 2.3 3.2 5.5 0.0 1.5 4.0 0.5 0.0 2.2 0.0 1.3 1.5 2.0 1.5 0.0 0.0 0.0 1.4 185.3 0.7 0.0 0.0 1.3 2.0 1.9 1.9 0.0 8.4 0.0 0.2 1.2 1.9 8.2 2.9 2.5 0.0 1.4 0.9 0.4 0.0 0.1 0.8 0.0 1.9 10.6 0.0 0.0 3.1 39.2 0.0 0.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.3 1.7 0.2 0.2 1.8 4.3 0.8 213.4 0.0 0.4 0.1 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBTB42 ZNF925 ENSG00000179627 "Zinc finger and BTB domain containing 42" B2RXF5 14 104800596-104804712 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 11.7;Exocrine glandular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "eosinophil: 5.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HDLM-2: 19.3;MCF7: 33.7;T-47d: 26.9" "Not detected" "Not detected" HPA066961 Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA066961: AB_2685756" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (8.68e-2)" "unprognostic (1.59e-1)" "unprognostic (6.99e-2)" "unprognostic (6.67e-2)" "unprognostic (6.17e-3)" "unprognostic (2.56e-1)" "unprognostic (4.35e-1)" "unprognostic (2.70e-2)" "unprognostic (1.63e-1)" "unprognostic (3.42e-1)" "prognostic favorable (2.30e-9)" "unprognostic (1.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.58e-3)" "unprognostic (5.45e-2)" 2.3 3.5 1.1 1.7 1.1 0.3 3.3 1.0 0.9 1.7 1.5 3.0 3.2 2.2 1.8 4.8 4.5 1.8 4.5 0.9 1.2 4.1 5.5 4.3 1.4 1.8 1.4 1.1 11.5 2.2 1.0 1.1 1.3 6.2 1.8 0.4 6.3 3.3 6.5 2.6 2.9 1.4 1.4 2.2 6.5 2.4 1.2 1.4 4.7 2.6 1.3 2.3 2.2 1.0 1.3 4.4 1.3 5.3 1.0 1.1 5.4 1.9 2.0 3.4 3.0 2.8 5.1 0.4 3.7 1.9 2.3 5.8 1.1 1.8 0.5 19.3 1.3 1.8 2.3 3.3 1.6 0.4 10.3 2.0 2.1 1.4 0.7 2.4 1.5 3.8 3.0 2.9 0.6 33.7 3.6 2.8 0.8 8.9 4.0 5.0 0.3 2.7 2.5 8.6 5.9 2.5 1.5 7.9 3.4 1.2 26.9 2.1 2.4 1.3 3.0 0.3 0.6 3.1 1.8 0.3 4.3 1.8 2.8 0.0 0.1 5.4 0.3 0.0 0.5 0.4 0.4 0.1 0.0 0.4 0.3 0.4 0.0 0.1 0.0 0.4 0.3 0.2 1.1 1.1 1.0 0.9 0.9 1.2 1.8 1.4 1.3 1.4 1.2 1.0 3.1 3.2 11.7 0.3 1.2 0.4 5.0 1.9 1.2 0.3 8.1 3.4 4.4 5.7 8.2 0.0 0.0 1.2 1.1 4.3 3.9 4.2 2.6 2.3 1.2 2.6 5.4 4.4 0.0 13.5 1.9 1.1 3.1 3.9 0.0 2.3 2.5 7.3 1.1 0.0 0.0 6.4 2.0 2.5 0.6 0.9 0.6 0.9 1.8 0.0 0.8 2.8 5.2 0.5 0.0 7.5 3.2 0.4 0.7 6.9 3.4 4.3 3.1 0.4 0.0 1.5 1.6 8.4 3.4 3.4 0.1 0.8 1.8 0.5 4.9 5.1 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZFP1 "FLJ34243, ZNF475" ENSG00000184517 "ZFP1 zinc finger protein" Q6P2D0 16 75148494-75172236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-698: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044916, HPA062910" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA044916: AB_2679144, HPA062910: AB_2684902" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.24e-5)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.99e-1)" "unprognostic (1.50e-1)" "unprognostic (4.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (9.80e-4)" "unprognostic (5.55e-1)" "unprognostic (6.64e-2)" "unprognostic (2.08e-1)" 4.2 3.3 3.7 1.7 4.4 1.8 3.9 4.4 5.1 4.8 1.7 5.4 1.7 5.7 2.2 2.7 4.8 2.7 3.6 4.6 3.4 3.7 11.1 3.5 3.1 3.3 3.0 5.1 2.1 4.6 3.8 3.0 3.3 2.9 2.0 5.8 2.2 3.1 5.8 2.7 3.0 4.0 3.7 2.5 3.0 4.2 3.7 8.2 4.8 4.3 3.2 4.7 3.6 5.3 3.1 6.6 9.1 8.2 5.1 6.7 3.6 3.7 4.4 8.2 9.8 5.3 2.4 13.1 4.2 3.0 3.2 3.8 8.1 5.6 9.5 7.2 4.9 4.8 2.4 4.0 4.4 4.7 14.8 4.5 5.5 6.1 7.9 8.6 5.4 12.3 5.6 2.7 6.4 11.9 16.4 4.6 2.8 2.6 2.5 15.1 4.0 4.2 3.6 2.8 9.0 7.2 9.0 2.7 3.5 2.3 6.0 3.9 3.7 7.4 7.9 3.4 4.3 11.2 11.5 28.6 3.6 6.7 5.8 1.1 0.7 0.2 1.5 1.2 1.6 1.2 1.1 1.7 0.7 1.6 1.4 1.5 0.0 1.9 0.5 0.3 1.7 0.9 3.7 4.4 4.4 5.1 4.6 3.4 3.3 3.0 3.3 3.7 3.7 5.3 5.4 6.4 4.8 6.8 5.1 5.4 2.5 2.3 5.7 6.9 3.8 3.4 4.2 1.5 2.0 1.8 0.0 2.9 7.6 1.0 1.9 3.6 4.6 2.9 7.5 5.3 7.2 4.6 9.5 2.3 2.7 5.9 0.0 3.9 1.3 5.1 3.9 11.7 2.0 13.5 8.5 0.9 0.0 4.1 2.7 5.2 3.4 1.8 1.8 7.5 3.6 6.8 4.1 7.1 11.7 1.6 1.0 4.1 2.7 2.3 0.8 3.6 2.6 3.8 0.0 5.6 8.2 15.9 8.8 5.0 5.8 4.1 5.5 4.7 1.8 2.4 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.5;Early spermatids: 106.3;Excitatory neurons: 99.0;Inhibitory neurons: 96.5;Oligodendrocyte precursor cells: 139.7;Oligodendrocytes: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" 14.4 15.4 33.8 6.5 32.8 3.4 13.3 31.6 27.4 11.6 16.4 19.8 8.6 15.8 5.7 13.6 15.7 8.4 12.2 30.2 27.7 26.4 17.2 11.6 4.5 37.6 32.1 16.3 11.9 15.4 7.8 4.9 29.9 10.6 8.0 10.8 5.7 11.9 28.5 11.0 11.4 12.1 29.4 4.3 15.5 35.0 36.0 7.0 19.0 20.1 4.8 18.1 11.0 28.6 22.5 6.3 6.6 14.2 52.6 56.3 7.6 31.0 35.4 28.3 19.1 11.4 2.9 15.6 14.7 58.5 7.6 7.0 7.9 39.2 30.0 4.3 7.1 6.6 8.6 8.8 21.6 7.6 7.9 34.6 18.7 21.3 27.3 19.2 12.3 11.7 6.2 10.6 38.3 45.0 11.9 4.5 2.9 10.4 23.0 5.8 18.6 6.2 38.6 6.7 23.0 8.3 20.7 12.0 7.4 5.7 11.6 10.5 19.9 70.2 10.8 25.0 15.5 12.2 8.0 6.9 28.9 11.0 11.4 0.1 0.1 0.4 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.6 0.4 0.3 0.1 0.6 0.2 0.1 0.2 0.1 33.8 32.8 31.6 27.4 30.2 27.7 37.6 32.1 29.9 29.4 36.0 28.6 29.8 19.2 16.4 370.5 4.7 2.9 3.9 2.6 2.8 19.5 6.3 4.7 12.7 17.2 5.8 22.0 4.2 0.6 3.8 5.5 11.7 3.7 106.3 12.3 33.2 15.1 14.9 3.8 99.0 2.7 2.7 20.5 6.6 26.3 1.3 3.7 16.4 31.6 3.0 40.4 96.5 5.6 4.1 3.5 1.7 32.3 18.6 3.5 1.8 52.5 1.9 28.6 1.0 139.7 142.4 4.6 1.3 24.5 2.7 2.6 12.6 27.0 3.2 7.1 26.3 41.2 10.9 11.0 5.2 6.3 3.7 0.4 2.7 19.7 4.7 2.3 ZNF233 FLJ38032 ENSG00000159915 "Zinc finger protein 233" A6NK53 19 44259880-44275317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.2" "Group enriched" "Detected in some" 4 "Early spermatids: 40.9;Spermatocytes: 38.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 6.9;U-266/84: 7.6" HPA020975 Uncertain Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA020975: AB_1859145" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (7.37e-3)" "unprognostic (2.77e-2)" "unprognostic (9.07e-3)" "unprognostic (1.48e-1)" "unprognostic (4.20e-3)" "unprognostic (1.65e-1)" "unprognostic (6.28e-3)" "unprognostic (6.88e-2)" "unprognostic (3.47e-2)" "unprognostic (2.71e-4)" "unprognostic (1.55e-1)" 0.4 1.1 1.8 1.1 1.9 1.8 1.5 3.4 3.1 0.7 0.4 3.0 0.9 0.4 1.6 0.6 1.3 0.9 3.2 1.5 1.8 1.3 0.5 0.6 1.3 1.2 0.1 0.5 0.8 1.7 3.1 1.3 1.5 2.7 1.3 4.9 0.9 1.0 1.7 1.6 1.0 0.4 0.3 1.3 1.1 14.2 0.9 1.5 1.9 0.6 0.6 0.8 0.4 2.5 0.4 1.8 2.0 1.9 2.2 0.4 0.5 0.7 0.6 0.7 1.2 1.5 2.1 0.6 1.9 0.6 1.1 0.6 0.0 0.5 0.8 0.3 2.4 1.0 2.5 1.7 1.5 0.7 0.8 0.5 0.3 0.5 1.3 2.9 0.9 0.7 0.8 3.8 0.1 0.7 0.6 0.5 2.1 0.4 0.3 1.2 0.2 0.8 0.4 1.2 2.8 4.4 0.7 0.5 1.3 3.7 3.5 1.0 0.3 0.6 0.4 0.4 0.4 6.9 7.6 1.2 3.0 0.5 0.9 1.5 0.3 0.2 0.5 0.3 0.4 0.9 0.4 0.3 0.1 1.3 0.6 0.7 0.7 1.1 0.3 1.3 0.7 0.1 1.8 1.9 3.4 3.1 1.5 1.8 1.2 0.1 1.5 0.3 0.9 2.5 0.5 0.0 0.5 2.6 0.4 0.0 0.2 0.2 0.0 3.7 1.1 0.4 4.6 0.0 0.3 0.0 0.0 0.5 0.2 0.3 0.0 0.6 40.9 1.3 0.3 0.9 1.2 0.4 9.0 0.0 0.1 0.6 0.5 0.5 0.0 0.7 0.0 0.0 0.6 0.0 7.9 0.2 2.0 0.0 0.0 8.5 0.6 0.1 0.0 1.0 0.0 1.9 0.0 4.5 5.7 0.1 0.1 0.7 0.0 0.5 0.8 0.0 0.4 4.0 0.0 0.6 0.4 38.6 1.9 0.0 0.0 0.0 0.3 1.1 0.4 0.1 ZNF350 "ZBRK1, ZFQR" ENSG00000256683 "Zinc finger protein 350" Q9GZX5 19 51964340-51986856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001521 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nuclear bodies" "HPA001521: AB_1080705" "unprognostic (7.26e-3)" "unprognostic (4.02e-2)" "unprognostic (2.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.03e-2)" "unprognostic (4.17e-2)" "unprognostic (7.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.08e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.25e-3)" "unprognostic (6.64e-3)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (8.30e-2)" "prognostic favorable (2.54e-4)" 6.6 4.4 5.8 5.4 7.3 26.2 13.8 8.6 6.7 5.5 4.1 6.6 5.4 6.4 8.2 4.7 5.8 5.2 5.1 6.4 6.5 7.0 5.3 6.3 9.7 6.0 5.7 8.3 4.5 9.2 4.8 9.3 6.1 27.5 9.1 9.7 6.4 6.3 4.5 7.5 6.1 5.8 5.8 9.0 7.3 6.3 6.5 9.0 9.8 5.9 9.1 6.2 5.2 7.2 0.8 4.4 5.6 6.8 7.5 6.7 1.1 4.6 6.5 4.8 9.5 0.0 3.5 2.1 3.6 5.5 8.8 5.8 4.9 6.5 6.6 0.0 10.5 8.6 7.5 3.9 6.3 2.2 10.1 9.5 9.9 6.4 6.6 9.4 5.5 3.5 2.3 0.1 5.8 2.8 8.5 10.2 3.7 0.5 6.8 4.0 8.0 6.9 7.6 11.9 4.7 6.3 0.0 6.0 5.0 7.9 9.8 7.7 5.9 5.2 3.7 3.1 4.7 1.6 2.8 2.7 1.0 0.1 5.6 65.3 11.2 26.9 16.2 12.7 16.4 16.8 15.3 15.6 13.6 17.2 17.7 14.2 30.8 21.5 16.2 8.8 13.4 8.1 5.8 7.3 8.6 6.7 6.4 6.5 6.0 5.7 6.1 5.8 6.5 7.2 9.1 0.0 7.3 4.6 13.1 5.9 11.0 11.1 5.7 9.9 6.0 5.3 6.6 2.8 10.7 9.2 12.5 12.2 12.9 5.1 7.9 6.7 13.0 4.5 4.7 8.0 7.3 2.5 4.2 5.3 9.9 7.1 3.6 6.7 12.0 9.7 6.4 3.1 7.8 6.7 4.1 5.9 16.2 9.5 12.0 3.4 11.1 10.8 12.4 6.5 11.6 7.9 23.7 4.0 9.1 6.0 5.7 6.0 7.5 14.5 7.6 3.9 7.8 13.1 0.0 7.2 8.4 10.2 5.7 3.5 7.0 23.1 15.1 6.8 3.8 13.4 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;skeletal muscle: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 75.4;Late spermatids: 115.7;Microglial cells: 53.4;Oligodendrocyte precursor cells: 38.7;Peritubular cells: 54.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 62.6;NTERA-2: 33.2;REH: 27.5;SCLC-21H: 35.1;SH-SY5Y: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-3)" "unprognostic (3.37e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.77e-1)" "unprognostic (9.13e-2)" "unprognostic (8.97e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.92e-2)" "unprognostic (5.84e-2)" 9.1 2.9 13.5 2.3 9.6 0.3 6.7 14.0 10.2 6.3 1.0 4.3 1.3 5.4 3.4 4.7 9.3 5.8 7.8 9.7 11.0 2.0 0.7 2.9 1.9 14.9 30.4 7.6 3.4 3.0 4.0 4.2 11.8 6.0 2.7 3.6 2.8 9.5 27.5 2.0 2.6 6.5 8.6 1.4 2.0 4.5 26.3 1.8 4.3 14.7 1.2 3.9 5.4 7.8 0.0 0.0 62.6 3.3 5.1 0.6 7.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 1.4 0.0 0.0 1.9 0.5 0.0 3.6 0.1 0.2 0.0 0.0 4.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 8.8 0.4 33.2 0.0 0.0 27.5 0.1 0.0 0.0 1.7 35.1 87.7 0.0 0.1 0.0 17.6 0.0 0.0 0.0 0.0 1.0 16.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.5 9.6 14.0 10.2 9.7 11.0 14.9 30.4 11.8 8.6 26.3 7.8 12.7 0.0 0.0 75.4 0.0 2.7 0.3 0.1 1.2 9.8 0.6 0.6 2.6 0.0 0.0 0.0 0.0 0.5 0.1 2.3 1.9 0.2 23.5 2.7 7.6 11.4 0.0 0.0 10.9 0.2 0.7 15.8 0.0 0.6 0.0 1.6 15.4 0.9 0.7 0.0 7.4 1.0 0.0 0.3 5.1 115.7 27.7 0.4 1.8 53.4 0.0 11.7 0.0 38.7 5.1 0.2 0.4 54.5 0.2 0.1 0.2 0.6 0.0 1.1 0.0 4.5 6.4 0.8 1.9 0.1 1.7 0.3 0.3 5.5 0.7 0.1 ZNF432 KIAA0798 ENSG00000256087 "Zinc finger protein 432" O94892 19 52031378-52095738 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 26.9;Rod photoreceptor cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA052082, HPA060274, HPA065606" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA052082: AB_2681719, HPA060274: AB_2684238, HPA065606: AB_2685518" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (1.92e-1)" "unprognostic (7.04e-3)" "unprognostic (1.08e-2)" "unprognostic (2.41e-3)" "unprognostic (3.19e-2)" "unprognostic (2.56e-1)" "unprognostic (6.92e-2)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (5.49e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "prognostic favorable (4.11e-5)" 6.3 13.4 3.2 3.7 3.9 8.0 6.5 5.7 3.7 6.5 8.8 5.5 5.2 7.0 8.7 6.6 6.0 3.5 6.0 3.4 5.5 5.1 4.1 5.6 4.3 3.9 3.7 6.8 18.0 5.6 12.4 4.4 3.9 11.8 4.3 24.6 7.1 4.5 4.1 7.8 5.2 4.3 2.9 4.4 6.4 7.2 4.3 4.0 6.7 4.4 4.1 5.0 6.5 4.8 4.6 3.7 8.2 13.0 5.6 7.2 2.8 5.2 3.9 3.7 5.9 3.2 2.7 3.1 1.6 5.6 4.0 3.4 4.8 4.5 6.4 3.2 11.8 9.5 9.2 6.0 2.6 0.0 8.5 7.3 3.6 5.4 7.9 7.1 4.9 3.7 2.6 14.0 6.8 2.6 9.3 5.2 3.0 2.4 6.3 4.9 9.5 5.4 5.5 22.2 4.8 5.0 8.1 4.4 2.6 5.8 3.9 3.7 7.0 3.1 4.7 3.7 5.5 7.2 10.7 7.5 7.2 0.8 6.1 0.9 1.1 1.3 1.4 1.3 1.0 1.9 0.8 0.8 0.9 1.2 1.5 1.1 1.0 0.6 0.6 0.6 1.2 0.8 3.2 3.9 5.7 3.7 3.4 5.5 3.9 3.7 3.9 2.9 4.3 4.8 6.2 16.0 10.0 8.1 8.0 2.0 3.3 3.4 3.4 9.8 3.8 3.2 6.0 2.8 11.6 9.2 16.7 2.7 6.4 3.7 3.9 3.5 14.7 11.9 6.4 5.7 10.2 2.5 9.4 1.6 5.8 5.8 6.6 9.0 12.6 7.8 3.9 1.3 2.3 26.9 6.7 4.9 4.1 4.1 1.3 12.4 3.7 3.2 3.6 9.4 3.8 7.7 10.3 9.0 6.9 2.1 5.2 4.5 4.0 3.6 2.0 2.7 11.6 30.7 6.6 7.1 6.4 10.0 8.4 2.2 2.3 4.9 6.5 4.2 3.1 3.3 ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Microglial cells: 53.4;Oligodendrocyte precursor cells: 221.7;Oligodendrocytes: 104.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cell line enhanced" "Detected in many" "AF22: 67.6;fHDF/TERT166: 32.7;HUVEC TERT2: 46.9;THP-1: 38.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)" 13.4 11.9 8.8 3.1 10.5 2.3 11.4 95.9 9.5 10.8 29.9 4.7 1.7 15.3 4.3 3.9 9.0 10.6 9.1 6.0 14.7 3.2 1.2 6.3 3.8 17.4 14.3 20.5 1.2 1.1 7.6 8.6 21.2 2.6 3.6 5.7 9.0 3.0 3.7 6.1 4.4 13.6 12.4 21.0 2.7 3.6 10.8 4.3 6.8 6.0 2.8 5.8 6.8 13.5 0.1 0.0 67.6 0.1 10.6 18.4 0.2 10.0 14.3 3.4 2.1 0.0 0.1 0.0 0.0 32.7 0.0 0.3 0.0 0.0 2.8 0.0 4.0 14.0 0.6 0.5 1.9 0.0 20.2 23.0 0.0 0.3 0.0 0.0 46.9 16.4 0.3 0.1 6.0 0.0 9.2 0.0 4.7 0.0 0.0 0.0 15.2 1.1 0.0 0.0 8.7 5.5 0.8 0.0 0.0 6.1 0.0 38.9 26.9 26.5 2.0 8.0 1.5 0.1 0.0 0.3 10.0 0.0 22.2 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 8.8 0.0 0.1 8.8 10.5 95.9 9.5 6.0 14.7 17.4 14.3 21.2 12.4 10.8 13.5 19.0 0.0 3.0 170.1 0.3 3.7 0.1 0.0 1.2 42.4 8.0 10.9 11.9 0.0 0.6 0.0 2.1 0.1 1.7 0.0 0.0 0.0 2.1 0.5 3.3 28.6 1.2 13.9 16.5 0.0 0.0 21.4 0.0 0.2 13.3 4.7 20.3 0.0 0.1 15.2 22.7 0.1 0.0 0.6 5.5 3.3 9.9 0.9 14.2 53.4 0.1 0.7 0.0 221.7 104.6 0.0 0.0 7.9 0.1 0.2 0.0 4.0 1.5 3.0 0.0 13.7 6.0 0.1 6.1 0.8 4.4 0.1 0.8 17.2 0.0 0.2 ZNF532 FLJ10697 ENSG00000074657 "Zinc finger protein 532" Q9HCE3 18 58862600-58986480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Excitatory neurons: 86.9;Inhibitory neurons: 90.9;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 118.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015322 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015322: AB_2304947" "unprognostic (3.43e-1)" "unprognostic (4.36e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.46e-5)" "unprognostic (4.24e-1)" "unprognostic (5.84e-2)" "unprognostic (1.50e-3)" "unprognostic (7.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-3)" "unprognostic (1.90e-1)" "unprognostic (7.60e-3)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (5.76e-4)" 24.0 12.5 33.5 15.7 53.1 1.4 17.9 73.9 39.8 30.3 12.4 25.9 7.2 65.1 20.1 22.3 26.2 24.5 36.0 34.3 45.0 14.1 4.2 19.9 14.2 55.2 44.2 52.8 6.8 16.3 15.7 26.4 56.6 48.0 13.3 25.7 15.8 34.1 61.1 16.5 12.0 41.4 33.8 17.0 12.8 24.2 46.1 11.9 24.7 49.8 17.4 23.0 21.3 84.8 21.3 30.0 118.8 63.4 18.5 42.2 5.8 37.6 35.2 26.0 23.4 10.2 23.0 26.5 28.3 47.2 12.9 34.1 1.0 29.7 26.7 19.5 25.0 0.0 51.8 0.6 24.5 0.2 0.2 33.1 54.5 27.2 49.5 34.4 28.8 0.0 0.3 31.9 30.8 0.0 0.2 0.3 63.0 1.0 19.9 0.6 31.6 4.2 18.1 2.8 27.1 70.3 24.2 2.6 40.8 78.8 30.3 17.3 22.0 70.7 50.1 0.5 30.7 0.4 21.7 7.3 24.0 0.0 55.2 0.0 0.3 0.0 0.4 1.1 0.1 3.7 0.2 0.2 0.7 1.6 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.4 33.5 53.1 73.9 39.8 34.3 45.0 55.2 44.2 56.6 33.8 46.1 84.8 16.6 12.8 12.2 90.1 13.2 10.6 12.5 8.0 12.0 28.8 9.3 8.8 17.0 5.7 10.1 1.8 27.1 2.0 1.4 0.3 0.0 4.9 4.9 8.3 48.3 24.2 4.2 0.0 86.9 0.5 2.7 17.9 3.1 10.0 0.0 15.8 14.6 0.1 4.4 35.3 90.9 0.2 4.1 9.1 14.3 3.5 11.5 9.2 8.8 53.4 5.2 22.1 0.0 130.2 178.2 6.0 1.4 18.0 8.6 33.5 0.0 1.6 8.8 9.7 13.1 15.5 24.2 5.5 17.2 8.9 9.2 3.4 4.3 5.0 0.3 11.9 ZNF57 ZNF424 ENSG00000171970 "Zinc finger protein 57" Q68EA5 19 2900898-2918473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Early spermatids: 95.2;Late spermatids: 64.7;Squamous epithelial cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061915 Approved Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA061915: AB_2684635" "unprognostic (3.59e-2)" "unprognostic (1.53e-3)" "unprognostic (1.91e-2)" "unprognostic (8.86e-3)" "unprognostic (3.32e-2)" "unprognostic (3.07e-2)" "unprognostic (7.66e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.35e-1)" "unprognostic (4.04e-2)" "prognostic favorable (7.72e-4)" "unprognostic (2.34e-3)" "prognostic favorable (4.11e-9)" "unprognostic (6.26e-3)" "unprognostic (2.82e-2)" "unprognostic (7.35e-2)" "unprognostic (6.49e-3)" 2.8 2.5 1.8 2.0 1.9 4.0 6.4 8.0 3.2 5.5 1.3 8.2 7.2 2.6 3.6 9.1 4.2 1.9 3.0 2.1 1.8 4.6 3.4 3.3 2.8 2.0 1.9 3.7 4.0 4.0 2.9 4.8 2.2 3.9 9.2 4.2 4.4 3.5 1.7 18.3 6.2 1.8 1.5 2.4 11.7 25.9 2.1 3.8 4.6 2.4 3.3 3.3 7.9 2.1 7.4 3.4 4.7 6.8 4.4 3.8 7.8 3.1 2.5 4.9 5.1 7.1 2.9 6.3 3.8 2.5 7.1 8.5 7.5 10.7 6.0 0.0 3.9 3.7 3.8 9.6 3.3 0.0 6.5 3.0 11.8 4.3 9.3 4.0 3.7 14.8 6.6 0.1 3.8 7.5 9.7 4.1 3.0 8.7 5.9 8.9 14.1 1.4 6.7 12.0 2.3 3.5 4.6 8.4 3.1 6.6 5.2 6.1 2.9 3.3 3.2 7.7 4.4 1.3 7.4 3.0 2.7 1.0 2.7 0.0 2.4 1.1 4.4 4.2 3.6 3.2 4.8 4.5 2.6 3.6 5.4 4.8 0.9 5.1 2.3 2.5 5.5 3.0 1.8 1.9 8.0 3.2 2.1 1.8 2.0 1.9 2.2 1.5 2.1 2.1 2.2 0.0 5.3 1.6 0.8 21.4 20.3 8.1 30.7 2.2 3.4 3.8 4.1 1.5 7.8 0.0 6.2 4.4 1.9 13.5 3.9 3.1 95.2 7.4 3.4 2.1 0.0 0.4 2.6 2.3 3.7 2.8 7.7 12.3 0.0 2.3 1.4 1.9 2.3 1.7 2.7 7.4 8.2 1.0 2.7 64.7 2.5 1.3 5.4 0.0 1.7 1.9 0.0 1.0 1.5 1.5 9.5 3.0 0.2 5.4 19.8 3.4 4.2 2.8 0.0 0.8 2.5 5.7 9.7 36.6 28.7 6.6 1.7 3.1 8.1 9.7 ZNF589 SZF1 ENSG00000164048 "Zinc finger protein 589" Q86UQ0 3 48241100-48299253 "Predicted intracellular proteins, Transcription factors" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9" "Cancer enhanced" "Detected in all" "testis cancer: 15.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HAP1: 44.1;NTERA-2: 71.1" HPA003145 Uncertain Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA003145: AB_1080738" "unprognostic (2.49e-3)" "prognostic favorable (2.50e-4)" "unprognostic (9.14e-2)" "unprognostic (7.34e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.01e-5)" "prognostic favorable (6.45e-5)" "unprognostic (2.64e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.21e-4)" "unprognostic (8.02e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-2)" "unprognostic (3.45e-2)" "unprognostic (9.57e-3)" "unprognostic (2.19e-2)" 7.2 8.5 9.6 6.7 9.7 5.8 6.9 14.9 11.2 11.2 2.3 8.3 3.8 7.6 20.1 10.2 8.8 4.6 6.2 11.0 9.3 7.1 3.7 10.1 12.3 7.9 7.9 13.6 6.5 5.9 7.8 3.0 7.7 18.3 6.6 14.8 6.6 15.7 6.1 9.8 16.1 6.0 7.2 24.1 7.9 6.6 8.9 8.1 16.6 4.2 12.2 8.5 10.7 10.2 4.5 3.2 12.7 10.8 15.8 8.7 16.1 4.6 3.5 5.2 6.9 6.8 6.0 17.8 3.3 4.7 4.0 3.9 44.1 11.2 4.2 11.5 10.5 22.5 14.9 5.4 2.9 5.4 5.6 2.8 7.5 6.4 4.3 5.7 9.0 13.7 15.4 4.5 2.8 4.5 6.8 4.1 71.1 4.3 6.6 3.3 4.6 6.8 4.0 4.4 4.9 9.1 3.4 3.7 13.7 18.8 6.0 8.0 14.0 3.0 5.8 7.2 3.5 8.9 12.0 14.6 4.0 12.6 9.3 1.2 2.2 1.6 2.8 2.0 3.5 3.1 3.4 3.8 2.3 1.9 3.8 3.8 1.2 1.2 2.8 10.9 3.1 1.9 9.6 9.7 14.9 11.2 11.0 9.3 7.9 7.9 7.7 7.2 8.9 10.2 2.0 0.0 5.4 4.2 5.5 1.1 1.4 0.9 3.4 15.3 2.4 1.5 4.1 0.0 2.8 9.2 20.9 2.2 13.7 1.3 3.9 1.4 1.5 7.3 3.5 2.7 1.8 2.1 9.8 1.0 1.2 4.3 1.5 11.7 0.0 3.9 2.5 1.0 3.3 1.7 11.5 2.5 0.0 5.5 3.0 2.0 2.1 7.3 1.8 3.7 3.7 5.3 1.0 9.5 11.0 1.0 1.7 4.5 5.3 1.5 1.4 1.6 2.4 13.1 6.6 4.1 3.0 1.4 3.1 2.9 1.3 0.0 4.4 7.0 2.5 0.9 ZNF613 FLJ13590 ENSG00000176024 "Zinc finger protein 613" Q6PF04 19 51927147-51948759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 19.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 10.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026833 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA026833: AB_1859377" "unprognostic (1.10e-1)" "unprognostic (2.57e-1)" "unprognostic (9.27e-2)" "unprognostic (2.84e-1)" "unprognostic (9.31e-3)" "unprognostic (1.79e-1)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (2.73e-1)" "unprognostic (5.30e-2)" "unprognostic (5.30e-3)" "unprognostic (1.12e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-3)" "prognostic favorable (1.92e-6)" 3.2 3.2 3.4 2.6 3.8 1.4 7.0 4.6 4.2 3.1 3.2 5.2 2.2 3.5 3.8 3.4 3.2 2.8 3.5 3.5 5.1 4.9 2.9 3.8 4.2 4.0 4.2 3.8 2.5 6.0 3.2 6.6 3.9 19.4 5.0 7.2 2.9 4.0 2.7 3.6 2.9 4.1 3.5 4.3 2.8 2.8 4.0 5.6 4.3 3.5 4.2 3.6 2.8 4.2 2.9 3.8 6.2 6.3 5.5 5.7 1.5 5.0 7.8 6.4 8.1 1.3 3.5 2.7 2.6 6.1 5.8 3.2 6.3 6.1 6.9 0.1 8.2 5.4 2.8 3.7 5.5 0.3 7.2 4.6 7.1 6.2 5.0 7.7 7.1 6.2 2.5 0.0 6.6 0.5 8.9 4.1 4.5 1.3 5.9 4.7 7.0 2.8 6.5 9.9 4.2 4.0 8.0 5.8 4.6 9.8 6.3 6.4 4.6 2.7 5.3 2.2 5.3 5.5 0.0 4.9 0.1 0.0 8.5 5.7 5.2 10.5 7.1 5.3 6.5 6.0 7.4 8.3 7.0 9.0 7.6 9.9 5.4 7.7 9.4 3.5 7.7 5.4 3.4 3.8 4.6 4.2 3.5 5.1 4.0 4.2 3.9 3.5 4.0 4.2 2.0 3.2 2.6 2.0 0.9 0.5 0.6 0.8 0.6 2.4 1.6 1.0 4.6 1.5 2.7 3.7 0.0 6.1 1.5 1.9 3.9 2.5 2.3 1.2 1.2 3.0 1.2 0.0 2.4 2.2 1.7 1.2 1.5 1.6 1.3 4.9 3.3 1.5 3.2 0.0 2.0 3.7 6.1 1.6 1.5 1.2 1.2 1.2 0.0 4.7 3.0 2.3 3.1 4.5 4.6 1.8 2.1 1.5 0.5 1.6 1.0 1.4 0.5 4.0 0.0 1.6 1.5 1.9 2.1 1.5 0.6 7.1 1.4 2.3 2.1 0.7 ZNF674 "MRX92, ZNF673B" ENSG00000251192 "Zinc finger protein 674" Q2M3X9 X 46497727-46545457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 13.5;Inhibitory neurons: 11.4;Oligodendrocytes: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA031026, HPA065295" Uncertain Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA031026: AB_10602690, HPA065295: AB_2685456" "unprognostic (6.11e-4)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.30e-2)" "unprognostic (1.54e-2)" "unprognostic (3.39e-2)" "unprognostic (6.41e-5)" "unprognostic (2.74e-4)" "unprognostic (5.68e-2)" "unprognostic (2.43e-2)" "unprognostic (2.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (3.25e-4)" "unprognostic (8.45e-4)" 1.0 1.2 1.7 1.1 1.9 1.0 1.4 3.0 2.0 1.4 1.1 1.2 1.1 1.6 1.6 0.9 1.0 1.2 1.3 1.7 1.9 1.4 2.2 1.0 1.5 1.6 1.4 1.7 2.0 1.4 1.3 1.2 2.0 2.0 1.3 3.9 1.1 1.3 1.4 1.3 1.1 1.7 1.3 1.4 0.9 0.9 1.7 1.5 1.7 1.1 1.2 1.1 1.2 2.5 1.7 2.2 2.1 2.7 1.9 1.9 2.1 1.8 2.5 2.3 2.4 1.4 1.4 1.9 1.1 3.1 4.1 1.6 2.9 2.2 2.6 1.6 1.8 0.8 2.5 1.2 2.5 2.1 3.3 1.8 3.4 1.7 5.6 2.4 1.7 3.2 1.0 2.8 2.1 1.1 2.1 0.9 3.4 0.5 2.1 1.0 3.6 2.2 1.5 0.7 0.8 1.8 2.7 0.9 5.7 5.9 2.3 1.5 1.6 2.9 3.3 1.8 1.7 3.3 3.2 0.8 1.2 1.0 3.0 0.9 0.6 0.9 0.5 1.1 0.5 0.7 0.7 0.4 0.6 0.3 0.5 0.6 1.7 0.5 0.2 0.7 0.6 0.6 1.7 1.9 3.0 2.0 1.7 1.9 1.6 1.4 2.0 1.3 1.7 2.5 2.7 9.6 1.8 5.2 1.3 1.9 3.1 0.5 1.2 6.6 1.1 1.3 4.4 0.0 2.9 1.8 0.0 0.8 2.3 1.5 0.0 0.9 0.0 1.5 2.2 3.4 0.0 0.8 9.3 0.5 0.7 2.0 3.1 1.9 2.5 1.9 3.6 2.1 1.0 13.5 11.4 1.0 0.0 1.9 2.2 0.5 0.3 1.4 0.0 5.6 2.0 2.5 2.1 9.5 12.3 1.3 1.4 1.9 2.3 2.6 1.1 0.9 2.7 5.8 0.0 3.2 1.5 1.3 4.2 1.1 1.7 0.4 1.9 1.2 0.9 2.2 ZNF697 MGC45731 ENSG00000143067 "Zinc finger protein 697" Q5TEC3 1 119619377-119648266 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.0;Syncytiotrophoblasts: 19.8" "Cancer enhanced" "Detected in all" "melanoma: 14.4" "Region enhanced" "Detected in some" "basal ganglia: 3.3;cerebral cortex: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 42.8;WM-115: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049933 Uncertain Approved Nucleoplasm NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA049933: AB_2680958" "unprognostic (2.57e-1)" "unprognostic (7.02e-3)" "unprognostic (4.32e-2)" "unprognostic (2.45e-2)" "unprognostic (3.38e-1)" "unprognostic (9.79e-3)" "unprognostic (1.20e-3)" "unprognostic (1.30e-3)" "unprognostic (2.82e-1)" "unprognostic (1.45e-1)" "unprognostic (5.09e-2)" "unprognostic (1.14e-1)" "prognostic favorable (6.20e-5)" "unprognostic (1.19e-2)" "unprognostic (6.48e-2)" "unprognostic (3.53e-2)" "unprognostic (3.36e-1)" 4.1 2.9 0.9 1.4 3.3 1.0 3.4 0.0 3.2 1.5 0.0 1.3 1.7 2.2 2.3 0.8 1.4 1.5 4.3 1.5 0.0 7.5 3.1 4.4 0.6 0.0 0.0 2.0 2.8 4.9 2.8 6.9 0.0 4.2 1.4 0.9 5.4 1.0 2.1 1.6 1.5 1.2 0.0 1.4 1.8 3.1 0.2 0.5 3.2 1.9 0.4 2.0 1.0 0.0 2.0 1.0 4.9 1.6 6.4 7.0 6.6 8.8 12.2 5.1 4.6 3.1 0.4 0.0 2.9 4.9 4.0 2.2 3.8 8.7 11.9 0.0 3.8 3.3 2.0 5.9 12.2 2.2 2.2 11.9 2.4 11.4 24.2 5.6 10.1 2.8 3.0 0.4 2.3 1.5 0.0 1.6 26.1 1.8 2.9 0.0 11.8 0.2 2.4 4.5 1.1 6.8 2.0 2.1 42.8 15.4 1.0 3.1 23.4 8.4 10.7 6.0 15.4 1.2 2.0 0.0 11.9 2.3 42.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 3.3 0.0 3.2 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.5 1.3 0.1 2.2 1.5 2.5 0.6 0.8 1.7 0.6 8.8 1.5 1.9 1.8 0.0 7.9 0.0 0.7 3.9 1.8 1.6 1.1 2.6 3.5 2.4 0.0 17.0 0.9 2.3 4.3 1.5 1.8 0.0 5.5 3.3 4.2 2.6 0.0 6.9 2.1 4.1 3.7 12.0 3.6 4.7 3.1 5.4 4.7 2.7 1.1 0.0 8.0 0.6 2.1 3.3 6.4 0.0 3.7 1.8 6.4 0.4 0.9 6.6 0.5 5.4 1.3 1.5 0.4 1.8 19.8 0.1 5.3 1.8 0.9 ZNF761 "FLJ16231, FLJ35333, KIAA2033" ENSG00000160336 "Zinc finger protein 761" Q86XN6 19 53431984-53461862 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "prostate: 73.9" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 45.3" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (8.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.89e-2)" "unprognostic (1.39e-1)" "unprognostic (7.03e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (4.68e-2)" "unprognostic (3.74e-3)" "unprognostic (1.12e-1)" "unprognostic (2.19e-3)" "unprognostic (1.59e-1)" "unprognostic (2.33e-3)" "unprognostic (1.19e-1)" "unprognostic (4.13e-1)" "unprognostic (8.71e-2)" "unprognostic (1.38e-3)" 8.3 9.8 8.7 6.4 10.0 10.6 10.6 15.8 10.5 7.3 9.4 7.1 6.6 6.2 11.0 5.7 9.1 6.5 5.3 9.6 10.3 7.9 6.1 7.1 8.7 9.5 9.0 12.2 11.8 11.9 7.3 17.0 10.2 73.9 8.7 7.2 8.7 6.2 4.7 11.1 6.8 6.6 7.4 8.1 9.2 6.1 9.9 8.2 8.2 4.7 8.4 8.3 7.7 12.7 17.3 9.6 6.9 14.4 21.0 17.2 25.1 11.0 9.9 7.9 12.0 11.9 6.9 16.2 6.1 10.7 11.4 11.8 18.2 11.9 12.5 2.2 25.9 15.5 12.7 15.4 12.9 1.5 18.4 17.1 13.5 9.5 16.8 11.1 8.9 15.7 16.4 10.7 14.5 10.6 19.0 15.3 12.0 17.1 14.5 15.2 15.2 17.2 8.7 48.9 8.9 6.8 13.2 18.6 8.0 22.4 10.1 14.4 7.6 12.3 9.5 1.7 13.0 13.0 27.6 26.6 0.5 8.8 10.8 7.2 4.4 5.8 5.1 4.8 6.3 6.6 5.9 6.4 4.8 6.4 6.4 6.8 3.8 12.8 4.7 5.2 8.4 4.5 8.7 10.0 15.8 10.5 9.6 10.3 9.5 9.0 10.2 7.4 9.9 12.7 6.7 3.2 7.3 3.6 6.4 0.0 12.0 0.0 2.8 1.1 7.5 6.1 6.6 12.8 4.3 3.7 0.0 17.3 4.9 4.9 23.5 4.3 0.5 6.2 4.9 5.3 2.4 7.8 2.5 2.9 14.3 7.5 6.1 6.3 9.5 12.0 9.7 10.0 8.6 5.0 5.0 11.5 0.0 7.1 0.0 1.3 12.5 5.0 0.0 3.7 3.5 1.8 5.2 1.5 7.0 5.4 6.1 7.9 9.2 19.6 5.2 11.5 2.2 0.9 19.7 3.7 5.0 1.5 5.6 5.7 0.0 45.3 4.7 5.1 6.7 12.1 ZNF813 FLJ16542 ENSG00000198346 "Zinc finger protein 813" Q6ZN06 19 53467733-53496255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 18.1" HPA056406 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA056406: AB_2683119" "unprognostic (1.20e-1)" "unprognostic (3.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.98e-3)" "unprognostic (2.28e-1)" "unprognostic (3.61e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-3)" "unprognostic (3.39e-3)" "unprognostic (1.74e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-2)" "unprognostic (1.25e-3)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (6.56e-2)" 1.2 1.1 0.9 1.5 1.3 1.4 2.2 1.1 1.1 1.1 1.4 1.8 1.8 1.3 3.9 1.2 1.8 1.4 0.7 1.0 1.2 1.3 0.7 1.4 2.2 1.4 1.4 1.8 1.3 2.4 0.6 3.6 1.3 4.9 1.7 0.6 1.2 1.1 0.4 2.0 1.7 1.0 1.0 1.9 1.9 1.6 1.3 2.2 1.9 0.5 2.1 1.4 1.2 1.8 0.9 0.8 2.6 4.3 2.2 2.6 6.0 2.4 2.4 1.6 2.3 4.6 2.7 6.9 2.3 2.3 3.0 1.4 6.3 2.7 3.0 0.0 9.9 6.9 1.8 5.2 1.1 0.0 7.1 2.2 2.2 1.8 1.3 0.9 1.4 4.9 3.8 0.1 2.6 1.3 9.2 3.8 3.3 0.8 2.4 5.6 5.7 3.4 1.5 18.1 1.1 2.5 0.0 4.5 1.6 5.6 1.8 3.4 2.3 0.9 3.1 0.1 2.3 3.6 5.5 7.5 0.0 0.0 4.7 1.8 1.1 0.8 1.7 1.6 1.7 1.6 1.6 1.9 1.2 2.4 3.0 2.3 0.5 3.6 3.0 1.1 1.3 1.4 0.9 1.3 1.1 1.1 1.0 1.2 1.4 1.4 1.3 1.0 1.3 1.8 3.4 6.4 1.8 0.3 4.4 1.8 3.1 1.4 4.6 0.7 1.9 1.8 1.9 5.7 2.6 0.0 0.0 5.0 4.3 2.5 1.9 2.2 1.7 2.6 3.2 4.0 0.0 3.4 0.3 1.2 10.1 4.1 3.6 2.6 0.0 7.0 13.6 1.2 2.8 3.3 1.0 3.2 2.0 3.0 1.7 0.9 2.5 2.6 3.6 1.0 3.7 1.1 3.1 2.0 2.8 1.5 3.4 2.2 1.5 5.0 1.2 0.8 2.0 0.6 0.0 4.0 3.4 0.9 4.1 2.2 1.6 8.9 2.8 2.6 3.9 2.3 ZNF827 ENSG00000151612 "Zinc finger protein 827" Q17R98 4 145757627-145938823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 96.3;Excitatory neurons: 77.5;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021166 Uncertain Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA021166: AB_2670608" "unprognostic (2.75e-2)" "unprognostic (3.46e-3)" "unprognostic (2.79e-1)" "unprognostic (3.64e-1)" "unprognostic (3.90e-2)" "unprognostic (2.40e-2)" "unprognostic (3.77e-1)" "unprognostic (3.57e-1)" "unprognostic (1.57e-1)" "unprognostic (3.90e-2)" "unprognostic (7.64e-2)" "unprognostic (3.47e-1)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (7.85e-2)" "unprognostic (4.03e-2)" "unprognostic (1.88e-2)" 2.9 7.1 2.4 3.2 5.5 2.2 4.5 9.1 4.3 5.7 0.0 6.4 5.2 8.1 2.9 2.2 6.1 3.7 4.8 3.0 2.4 4.7 0.6 2.7 3.8 2.3 2.2 7.4 3.0 7.0 8.3 1.3 1.0 15.8 3.9 1.3 10.7 4.8 7.9 2.8 6.4 6.0 0.8 4.0 3.8 3.5 2.2 7.3 7.7 5.3 4.4 6.5 3.8 4.0 4.4 3.5 12.8 7.3 5.2 5.4 0.0 7.7 7.6 5.7 4.2 1.3 10.5 0.6 2.0 12.9 4.4 2.2 6.9 4.9 4.6 7.3 2.5 3.9 4.8 3.7 4.1 3.1 0.0 8.1 4.3 4.6 11.7 10.9 9.2 2.1 0.4 5.6 4.8 0.0 3.0 0.0 5.1 0.0 7.5 10.6 6.0 1.9 5.1 4.7 10.5 9.0 6.0 9.4 13.3 5.6 5.5 0.1 17.8 13.9 10.9 1.0 8.1 4.6 0.1 3.4 4.7 11.7 49.2 2.9 0.0 0.0 1.8 0.0 0.9 1.6 0.9 1.8 0.0 1.2 0.9 1.7 0.0 1.9 0.0 1.5 0.0 0.6 2.4 5.5 9.1 4.3 3.0 2.4 2.3 2.2 1.0 0.8 2.2 4.0 7.3 12.8 19.8 96.3 12.3 6.4 8.3 16.2 22.8 12.7 19.2 19.2 22.4 2.8 16.9 23.9 10.4 2.3 10.3 14.9 3.9 12.1 17.1 11.9 10.8 8.7 25.8 5.9 77.5 7.1 0.5 7.8 14.3 14.6 2.5 17.4 8.2 1.3 1.3 18.5 64.3 18.6 10.2 1.2 0.8 7.8 9.0 1.2 1.8 8.4 0.7 4.7 8.2 174.9 96.6 14.2 9.5 17.0 13.7 30.7 20.1 12.3 19.3 1.5 6.6 20.6 7.1 2.1 5.0 5.8 4.8 1.4 9.4 18.7 19.5 11.6 ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "dendritic cells: 20.5;Excitatory neurons: 19.5;NK-cells: 17.5;Plasma cells: 9.5;T-cells: 31.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Group enriched" "Detected in some" 6 "Daudi: 4.0;HMC-1: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)" 0.3 0.1 2.2 2.3 1.6 0.9 0.3 0.0 2.7 0.1 0.0 0.3 0.2 0.1 0.2 0.2 0.2 0.5 0.0 3.4 0.3 0.1 0.2 0.6 6.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.1 1.9 0.0 0.0 2.6 0.6 0.2 0.9 1.5 0.3 0.0 3.8 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 1.4 0.2 1.0 1.5 0.0 0.1 0.8 1.0 0.1 1.2 0.0 0.0 2.1 0.4 2.2 1.6 0.0 2.7 3.4 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 0.6 0.7 4.8 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.7 0.0 0.0 1.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 19.5 0.0 0.0 0.1 0.5 0.1 2.5 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 17.5 0.5 0.9 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.5 0.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 ZNF888 ENSG00000213793 "Zinc finger protein 888" P0CJ79 19 52904417-52923481 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 34.9;Glandular and luminal cells: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "RT4: 72.9" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "prognostic unfavorable (5.28e-4)" "unprognostic (7.35e-2)" "unprognostic (7.60e-2)" "unprognostic (6.88e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (5.00e-3)" "unprognostic (5.86e-3)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (4.31e-1)" "unprognostic (2.80e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (5.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.00e-3)" 1.7 1.8 0.9 2.3 0.8 5.0 3.2 1.7 1.1 11.1 1.4 5.3 2.9 4.6 4.8 3.0 8.2 5.1 0.9 0.8 0.9 5.9 0.8 2.9 3.5 0.7 0.7 2.7 5.5 2.2 0.9 4.8 0.8 9.0 8.1 1.0 3.8 6.8 0.4 3.4 2.5 1.5 0.7 2.9 7.6 1.0 0.8 3.4 3.0 0.9 3.5 9.5 3.8 0.9 6.3 0.1 2.0 6.5 1.9 1.1 9.2 4.8 2.9 3.8 6.5 4.6 4.2 6.1 6.4 2.8 4.0 3.7 4.8 3.9 5.9 2.8 7.5 5.3 5.8 4.9 0.9 0.0 8.8 2.2 3.7 3.7 4.5 1.8 2.3 4.0 9.9 0.3 1.0 1.7 6.3 6.7 3.1 0.3 5.2 4.1 3.9 2.9 14.4 72.9 0.9 2.9 0.0 8.4 1.2 4.6 6.3 8.6 3.2 0.8 3.8 1.5 5.4 1.6 3.2 7.2 0.2 4.0 4.4 0.4 0.8 1.0 0.6 0.5 0.8 0.5 0.6 0.8 1.0 0.7 0.7 0.6 0.4 1.3 0.8 2.0 0.9 0.6 0.9 0.8 1.7 1.1 0.8 0.9 0.7 0.7 0.8 0.7 0.8 0.9 1.6 6.4 3.6 1.0 0.7 0.0 0.2 0.2 0.0 0.0 1.7 2.2 1.1 0.0 2.5 9.2 0.0 0.1 2.0 0.1 0.0 2.9 0.0 34.9 5.2 0.7 0.0 0.0 0.8 1.6 0.1 0.8 0.5 41.0 0.0 4.4 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.0 1.6 0.0 1.0 1.0 0.0 0.0 1.0 0.7 3.3 0.0 0.0 0.7 0.0 0.0 1.6 5.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.3 1.0 1.7 0.0 0.1 ZSCAN1 "FLJ33779, ZNF915" ENSG00000152467 "Zinc finger and SCAN domain containing 1" Q8NBB4 19 58034025-58054631 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;pituitary gland: 15.9;testis: 8.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 11.7;Early spermatids: 28.2;Endometrial ciliated cells: 21.8;Late spermatids: 19.6;Spermatocytes: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HMC-1: 2.1;NTERA-2: 2.1;T-47d: 3.1" HPA007938 Uncertain Approved Nucleoli NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA007938: AB_1080768" "unprognostic (1.60e-3)" "unprognostic (2.44e-1)" "unprognostic (2.21e-1)" "unprognostic (3.58e-1)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (1.97e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-1)" "prognostic favorable (7.36e-4)" "unprognostic (1.41e-2)" "unprognostic (3.81e-2)" "unprognostic (1.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-2)" "unprognostic (3.60e-1)" 0.1 0.9 3.7 0.0 2.7 0.1 0.9 4.1 4.6 1.2 1.4 0.3 0.0 0.6 6.1 0.1 2.1 0.2 0.5 3.6 7.8 2.6 0.1 0.5 0.0 4.0 5.3 0.6 1.0 2.6 15.9 0.2 3.1 2.4 0.0 2.3 0.4 0.8 0.0 0.2 0.1 0.1 2.1 0.2 0.1 8.7 5.1 0.6 5.9 0.0 0.0 0.5 0.3 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.6 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 2.7 4.1 4.6 3.6 7.8 4.0 5.3 3.1 2.1 5.1 1.6 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.2 0.0 3.4 1.8 2.2 1.1 1.5 0.2 1.8 2.1 0.0 0.0 0.0 11.7 1.7 28.2 21.8 3.1 0.5 0.0 0.0 3.8 0.0 0.0 0.8 0.0 1.7 0.0 3.2 0.4 0.0 0.1 3.3 5.4 0.0 0.0 0.0 0.0 19.6 0.9 0.1 1.8 2.8 0.0 8.1 0.0 4.0 1.8 0.3 0.0 0.0 0.0 0.9 0.0 0.2 4.3 2.6 0.0 0.0 0.6 13.7 2.7 0.0 0.0 0.0 0.1 6.7 0.0 0.5 ZSCAN4 "FLJ35105, ZNF494" ENSG00000180532 "Zinc finger and SCAN domain containing 4" Q8NAM6 19 57668935-57679152 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 2.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Microglial cells: 1.0;Syncytiotrophoblasts: 1.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006491 Uncertain NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA006491: AB_10603385" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (2.75e-1)" "unprognostic (4.04e-2)" "unprognostic (2.59e-2)" "unprognostic (2.85e-3)" "unprognostic (1.06e-2)" "unprognostic (7.26e-2)" "unprognostic (1.45e-2)" "unprognostic (3.33e-1)" "unprognostic (1.45e-1)" "unprognostic (4.69e-5)" "unprognostic (1.73e-1)" 0.2 0.0 0.3 0.0 0.3 0.3 0.1 1.0 0.5 0.5 0.1 0.1 0.1 0.0 0.4 0.1 0.4 0.1 0.3 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.2 0.5 0.6 0.2 0.9 0.1 0.0 0.0 0.2 2.8 0.4 0.2 0.2 0.3 0.2 0.0 0.9 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.5 0.2 0.2 0.2 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4