Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.7;Gastric mucus-secreting cells: 21.9;Inhibitory neurons: 10.3;Microglial cells: 26.2;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 29.7;RT4: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 6.9 1.4 4.5 1.1 3.4 0.6 5.0 2.7 5.0 1.7 2.0 3.3 4.5 1.4 4.2 2.2 3.7 1.7 2.9 4.4 3.1 1.9 2.4 2.2 1.0 3.2 3.1 1.0 6.8 2.5 1.1 9.7 4.3 3.7 4.3 3.8 1.9 4.5 1.2 5.9 2.7 1.3 2.8 1.4 61.8 1.9 5.9 2.4 2.5 1.0 1.3 39.2 1.7 3.7 1.2 2.0 3.9 2.0 6.2 0.5 29.7 2.1 1.4 0.7 1.0 0.6 1.9 1.3 0.7 0.3 0.4 4.5 0.8 5.8 1.5 2.4 1.1 2.1 1.6 3.0 1.3 0.5 2.0 1.8 5.6 2.2 2.4 0.6 6.2 2.1 3.1 3.8 2.0 1.7 3.6 1.8 3.1 11.1 0.9 3.2 1.0 0.7 0.6 73.6 6.9 1.8 0.4 2.2 0.5 9.3 2.7 2.5 3.1 0.5 1.5 0.6 0.9 1.4 1.7 1.4 0.6 1.5 1.3 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.5 3.4 2.7 5.0 4.4 3.1 3.2 3.1 4.3 2.8 5.9 3.7 3.2 0.0 0.0 1.0 0.7 0.3 0.4 0.1 0.6 1.0 0.3 0.4 0.1 0.0 0.1 0.0 2.1 0.5 0.4 0.0 0.0 0.1 2.6 0.3 0.2 0.8 0.0 0.8 19.7 0.0 0.6 0.3 21.9 0.4 0.0 0.0 1.4 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 4.0 0.3 0.2 0.0 26.2 0.0 0.6 0.0 5.5 7.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.6 0.0 0.6 0.4 0.4 0.4 0.8 0.0 4.0 0.3 0.0 0.0 1.1 ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" 10.9 3.0 6.2 4.8 8.5 3.0 5.4 8.5 9.3 5.2 4.0 6.4 6.2 4.2 3.1 6.9 4.1 3.2 3.4 6.3 8.5 4.7 2.5 8.0 4.2 8.6 7.1 2.3 2.9 3.5 2.1 6.2 9.5 4.1 5.5 2.3 4.2 2.3 1.6 2.9 4.6 3.9 8.4 5.6 3.4 6.0 7.3 2.2 3.3 1.2 3.8 4.5 4.4 12.0 7.3 7.7 6.4 7.6 29.2 14.0 5.7 11.2 10.7 8.2 9.2 6.0 7.3 6.4 8.4 8.0 10.3 12.9 10.9 10.6 10.0 8.6 4.3 9.0 4.8 3.6 8.1 9.3 15.0 6.3 5.0 11.8 10.9 4.8 16.8 5.8 6.1 4.2 9.9 5.9 0.7 6.2 3.6 19.3 8.8 4.3 22.8 5.0 6.8 7.2 2.2 5.5 13.9 12.6 3.5 4.9 10.7 5.1 22.2 8.2 6.4 23.3 8.3 3.1 7.1 8.6 5.1 4.7 8.9 0.1 4.3 2.5 0.7 3.1 0.8 1.2 0.5 0.9 4.6 0.4 0.3 0.4 0.9 0.2 2.4 1.5 1.2 1.6 6.2 8.5 8.5 9.3 6.3 8.5 8.6 7.1 9.5 8.4 7.3 12.0 32.4 41.7 35.0 52.9 11.5 31.9 21.4 17.0 33.0 18.8 11.3 11.0 7.5 11.5 27.6 9.2 10.4 13.6 11.3 54.6 7.9 15.5 66.8 6.3 29.0 29.4 2.4 13.5 65.0 17.6 7.5 17.0 26.0 11.5 83.5 30.9 27.8 10.0 44.4 43.7 71.9 30.5 18.3 64.1 67.1 31.7 20.2 64.0 17.8 61.8 40.0 11.3 12.3 159.3 335.1 18.6 37.9 25.9 8.6 15.6 20.0 15.3 12.3 10.0 6.6 17.0 21.0 69.8 25.9 26.3 16.8 26.8 15.2 7.2 20.1 24.1 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTN2 ENSG00000077522 "Actinin alpha 2" P35609 1 236664141-236764631 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 53 "heart muscle: 772.7;skeletal muscle: 2134.7;tongue: 1262.2" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 1762.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 2.0;HEK 293: 1.3;HSkMC: 5.9;hTEC/SVTERT24-B: 2.7" "Region enhanced" "Detected in many" "basal ganglia: 66.6" "Region enhanced" "Detected in all" "basal ganglia: 44.5" "HPA006035, HPA008315" Enhanced Uncertain "Actin filaments" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095, HPA008315: AB_1844543" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (2.41e-2)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (4.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.97e-3)" "unprognostic (2.17e-2)" "unprognostic (2.80e-1)" "unprognostic (2.97e-1)" "unprognostic (2.66e-1)" "unprognostic (2.71e-11)" "unprognostic (1.30e-2)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" 0.7 0.2 12.0 0.0 26.3 0.1 0.9 8.0 20.1 0.3 11.0 0.4 0.0 0.5 0.0 21.8 0.5 0.7 772.7 13.2 12.1 0.5 0.3 3.9 0.2 9.7 8.1 1.1 1.6 0.1 0.5 0.1 10.7 16.1 0.0 1.3 18.4 0.1 2134.7 1.3 0.5 1.8 8.0 0.2 3.8 4.2 8.7 0.5 0.7 1262.2 0.1 3.5 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.0 0.0 0.2 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 26.3 8.0 20.1 13.2 12.1 9.7 8.1 10.7 8.0 8.7 14.2 0.3 0.0 0.6 18.6 0.0 0.3 0.4 0.0 1.2 2.6 0.4 0.5 1762.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.6 0.5 1.2 10.4 0.0 0.0 40.9 0.7 0.0 43.7 3.6 1.4 0.0 0.1 1.8 0.2 0.1 0.0 11.3 0.0 0.0 0.0 0.3 24.6 0.6 1.2 0.0 11.2 0.0 0.0 0.0 24.6 156.9 0.2 0.0 0.4 0.0 0.2 0.0 1.4 0.0 1.2 0.0 66.3 12.4 3.1 2.0 1.2 0.1 0.0 0.4 0.4 0.0 0.2 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.9;intestine: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.7;Intestinal goblet cells: 42.5;Oligodendrocytes: 43.6;Paneth cells: 64.4;Proximal enterocytes: 48.5;Undifferentiated cells: 50.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 15.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 108.1;CAPAN-2: 74.1;HMC-1: 71.0;OE19: 191.5;THP-1: 122.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA007033: AB_1846529, HPA012049: AB_1846527" "unprognostic (2.45e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (3.06e-1)" "unprognostic (9.10e-3)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-1)" "prognostic favorable (4.13e-5)" "unprognostic (5.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-2)" 4.9 3.8 51.2 11.2 55.8 9.8 3.4 57.3 73.6 4.1 11.2 43.2 19.7 6.0 0.6 9.0 8.8 6.0 8.1 59.4 42.9 22.3 3.6 10.4 3.8 63.5 63.1 1.5 13.3 6.1 4.7 2.7 56.9 6.6 22.8 1.6 4.6 2.9 0.7 3.9 26.8 8.3 48.7 17.2 19.6 1.1 55.4 0.9 7.6 0.5 2.1 8.9 3.8 85.9 108.1 4.0 0.1 3.7 1.4 0.2 1.1 3.6 0.1 0.7 0.1 43.1 74.1 0.2 10.3 0.5 0.2 44.5 5.9 8.1 0.5 0.6 4.7 0.0 6.0 25.4 1.7 0.7 71.0 1.8 21.4 0.2 0.0 0.1 0.0 3.1 0.4 0.0 0.0 33.2 0.1 30.1 3.2 191.5 0.0 14.4 0.2 0.4 4.7 25.0 3.1 1.0 3.3 1.3 0.5 0.4 25.9 122.6 0.6 0.8 2.8 0.1 0.3 0.0 0.2 0.0 0.2 22.3 3.3 1.0 6.5 3.3 6.0 7.3 2.8 1.1 1.6 5.5 5.1 0.9 0.5 2.6 3.1 1.6 11.7 0.3 0.8 4.0 51.2 55.8 57.3 73.6 59.4 42.9 63.5 63.1 56.9 48.7 55.4 85.9 0.4 0.0 10.3 2.9 3.6 1.0 2.9 3.3 2.8 4.7 2.5 1.5 8.5 7.2 2.9 7.3 0.0 0.3 19.4 97.7 9.8 3.9 0.2 8.6 0.9 0.5 16.2 0.0 13.2 4.6 0.9 1.5 17.9 7.6 7.0 1.3 0.0 0.6 12.2 0.0 12.6 42.5 4.1 23.0 15.7 0.4 0.0 22.1 10.6 2.8 13.2 1.3 15.5 3.0 43.6 17.5 64.4 0.0 2.6 3.0 48.5 7.1 8.2 1.1 0.0 0.1 1.9 0.3 1.2 1.1 1.3 0.7 9.0 0.0 50.6 5.5 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;granulocytes: 50.6;Kupffer cells: 65.1;Langerhans cells: 48.0;Macrophages: 45.4;Microglial cells: 52.5;monocytes: 42.4;NK-cells: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 81.0;HMC-1: 194.6;RPMI-8226: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" 8.1 3.9 6.8 23.9 7.3 24.7 5.6 7.8 8.8 3.9 6.9 8.2 4.1 3.7 2.3 14.3 7.6 12.4 5.5 6.2 10.6 1.6 3.8 23.3 27.1 14.4 11.4 19.4 2.0 1.6 2.0 14.5 12.8 2.7 8.8 0.8 4.0 2.1 2.2 13.7 8.6 7.8 10.9 29.7 7.8 1.9 12.9 19.3 2.4 3.5 24.5 7.6 4.7 19.1 16.3 18.5 0.7 2.6 1.9 24.0 1.7 9.7 4.5 8.1 7.0 23.4 28.4 4.2 25.4 41.0 0.5 50.5 22.3 10.0 8.9 50.7 6.9 81.0 18.4 5.8 20.6 10.6 194.6 12.0 8.5 5.7 8.3 4.4 2.3 17.7 30.4 7.9 10.5 9.2 5.8 34.9 3.5 8.4 31.1 5.7 7.1 100.6 5.0 1.1 4.0 9.8 5.4 2.0 4.8 4.4 0.1 38.7 17.6 0.9 25.5 2.9 3.6 0.3 0.6 8.5 9.3 32.6 3.4 9.2 7.6 2.8 6.9 10.7 5.1 2.8 2.9 5.2 12.2 3.3 2.5 3.6 4.1 9.5 18.1 6.8 4.4 5.6 6.8 7.3 7.8 8.8 6.2 10.6 14.4 11.4 12.8 10.9 12.9 19.1 1.4 19.2 35.9 2.0 15.4 3.7 0.4 0.6 1.2 1.2 1.3 2.8 1.0 0.0 7.9 0.0 6.2 11.6 42.8 3.3 0.0 1.9 1.5 6.7 6.5 1.9 0.0 12.4 6.4 0.2 1.8 9.2 3.6 13.6 50.6 4.7 1.4 0.5 35.2 0.0 3.8 0.7 0.0 65.1 48.0 1.3 0.6 45.4 5.4 52.5 42.4 0.5 76.2 3.5 0.7 4.2 10.4 1.2 15.6 0.5 0.1 0.2 1.0 0.8 6.6 28.3 2.2 0.0 1.5 7.2 4.0 4.0 26.6 16.0 2.3 1.3 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Alveolar cells type 1: 169.9;Breast glandular cells: 119.1;Endometrial ciliated cells: 194.3;Glandular and luminal cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" 39.7 15.0 25.1 23.1 34.8 5.5 49.5 27.2 27.9 46.0 35.1 55.3 53.1 35.8 39.8 126.3 63.8 33.6 47.3 21.0 29.7 45.0 66.8 57.0 10.9 30.2 30.0 31.2 61.2 32.8 38.3 44.9 29.5 47.0 62.7 47.1 79.0 28.6 34.0 54.7 71.1 23.9 12.3 34.2 50.6 31.3 31.2 7.3 51.4 28.4 27.3 29.2 61.8 35.3 67.7 20.7 141.2 50.8 13.5 11.3 104.8 26.8 13.7 22.7 27.9 88.8 41.1 12.0 48.3 16.3 35.5 31.8 59.2 55.1 40.3 76.1 61.1 0.4 9.1 67.9 20.3 7.7 30.8 8.0 36.2 38.1 89.0 36.1 42.8 25.6 137.4 45.5 14.9 29.2 0.8 0.6 34.7 95.6 9.5 43.6 37.1 51.2 41.3 32.5 65.1 39.6 27.2 101.7 40.5 131.1 12.2 2.8 62.9 10.6 50.5 45.7 44.9 0.8 59.3 24.5 31.4 15.4 93.7 0.0 0.1 0.0 0.3 0.1 0.2 1.1 0.3 0.1 0.2 0.7 0.0 0.1 0.9 0.0 0.1 0.0 0.2 0.0 25.1 34.8 27.2 27.9 21.0 29.7 30.2 30.0 29.5 12.3 31.2 35.3 173.8 169.9 89.3 0.0 6.4 0.0 0.0 0.0 0.0 0.0 119.1 83.3 0.0 0.0 40.9 95.6 0.0 30.6 4.7 0.0 21.5 70.1 0.0 194.3 42.0 36.3 0.0 0.0 0.0 39.4 35.0 20.5 0.0 273.4 8.8 65.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 10.9 0.0 0.0 0.0 0.0 65.7 0.0 0.0 4.5 0.0 0.0 35.0 46.7 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 42.1 5.6 13.2 0.0 0.0 AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 154.9;Excitatory neurons: 491.3;Inhibitory neurons: 300.7;Oligodendrocyte precursor cells: 211.6" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "Daudi: 51.1;U-698: 56.5" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" 3.3 1.6 3.1 6.2 3.9 11.2 11.6 17.4 13.2 3.5 0.0 5.1 1.1 7.7 0.8 3.5 4.5 2.2 4.3 9.7 5.0 1.4 1.7 6.5 14.2 2.2 0.0 6.3 0.4 0.1 4.4 6.2 1.8 16.2 2.2 4.2 1.9 2.5 0.7 0.9 6.0 5.9 0.0 7.3 4.6 5.4 0.0 7.7 1.2 0.7 12.2 6.7 2.2 9.8 0.2 0.0 18.0 6.4 0.0 0.6 0.0 2.8 0.7 5.6 1.9 0.0 0.0 51.1 0.1 3.8 12.4 0.2 0.5 0.0 4.0 14.3 6.3 0.0 0.0 0.0 0.4 0.2 12.4 0.8 0.0 12.8 0.2 13.8 0.0 2.2 0.3 0.1 0.0 0.1 4.3 0.3 1.8 0.0 3.2 7.5 0.0 0.3 0.0 0.0 17.4 6.5 0.0 0.3 11.0 1.5 17.9 16.5 6.7 19.1 3.4 0.5 2.9 0.8 0.1 56.5 15.9 1.5 2.0 0.6 0.5 0.1 0.0 0.5 0.3 31.0 0.2 0.0 5.1 44.2 1.9 0.0 0.0 1.0 0.4 23.9 0.0 0.8 3.1 3.9 17.4 13.2 9.7 5.0 2.2 0.0 1.8 0.0 0.0 9.8 1.2 6.4 40.9 41.8 154.9 1.8 0.4 0.0 1.8 21.8 78.9 37.7 11.1 0.0 3.7 0.0 12.5 0.4 32.8 0.1 0.0 0.0 33.9 0.9 19.8 6.0 22.9 3.4 491.3 0.0 0.2 13.5 1.1 1.1 0.0 31.6 0.7 1.2 1.8 47.1 300.7 0.5 0.0 9.2 18.2 38.5 10.8 16.5 14.2 66.5 5.2 6.8 0.0 211.6 46.7 0.0 0.1 21.1 0.8 14.3 0.1 1.9 0.0 1.7 0.0 1.1 8.5 10.5 9.8 0.0 1.3 0.1 6.1 5.7 0.6 0.3 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850361-99924023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 257.6;tongue: 212.0" "Cell type enhanced" "Detected in all" "Muller glia cells: 160.5;Theca cells: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 450000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: AB_2682455" "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favorable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 11.9 6.7 4.1 7.1 4.9 6.1 9.1 6.9 5.6 6.1 6.0 10.0 8.8 7.3 7.6 16.4 5.4 5.2 22.8 3.7 5.1 13.3 42.8 5.9 7.3 4.7 5.6 5.9 4.3 17.6 4.5 11.7 4.4 13.8 10.6 23.3 7.7 9.6 257.6 5.3 7.1 9.7 4.9 8.0 7.7 4.7 4.8 7.9 10.5 212.0 8.5 8.9 5.0 5.6 20.4 5.9 7.0 11.4 11.0 10.4 23.4 6.3 9.2 5.5 9.8 22.3 6.8 26.4 11.7 10.8 4.9 11.3 40.5 12.4 10.2 14.2 12.9 15.5 18.9 12.4 7.3 13.7 8.9 12.8 7.9 7.5 6.2 7.5 8.5 9.2 26.3 2.0 5.5 6.2 16.3 4.3 10.9 8.9 7.7 0.0 2.3 1.3 16.3 26.7 17.2 12.1 18.2 17.3 9.9 12.8 12.6 9.0 9.4 6.6 9.3 8.9 6.3 7.3 6.1 30.5 11.7 3.6 3.5 0.0 0.4 1.4 1.5 0.6 1.4 1.0 1.1 1.0 0.9 1.0 1.1 1.1 0.5 2.4 0.3 0.8 1.3 0.8 4.1 4.9 6.9 5.6 3.7 5.1 4.7 5.6 4.4 4.9 4.8 5.6 12.8 22.4 26.8 96.6 28.5 10.6 18.1 24.6 18.2 34.6 18.8 18.0 119.6 18.6 25.8 16.5 54.2 107.9 18.8 23.2 23.5 13.7 1.2 18.8 23.6 13.9 16.8 15.6 45.6 12.9 20.3 28.5 31.1 18.6 10.8 45.0 14.6 111.0 17.9 52.2 56.0 15.8 12.2 19.1 8.8 2.5 10.2 13.5 16.0 23.4 14.1 160.5 21.6 36.2 34.4 17.7 14.3 21.4 20.4 13.0 15.2 19.2 26.0 46.9 6.6 41.4 18.4 8.7 11.9 40.0 9.2 29.1 25.7 159.1 23.5 20.1 AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15571699-15585051 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Putrescine biosynthesis, Spermidine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 133.9;liver: 62.1;skeletal muscle: 34.2" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 306.8" "Group enriched" "Detected in all" 5 "colorectal cancer: 18.5;liver cancer: 25.3;renal cancer: 11.2;stomach cancer: 11.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.1;T-cells: 8.4" "Cell line enhanced" "Detected in many" "CACO-2: 36.7;Hep G2: 92.6;RPMI-8226: 22.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA026443, HPA028321" Enhanced NA NA 240000 "Cluster 20: T-cells - T-cell receptor" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026443: AB_1844644, HPA028321: AB_10600779" "unprognostic (2.27e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-3)" "unprognostic (3.60e-2)" "unprognostic (8.72e-2)" "unprognostic (6.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.13e-4)" "unprognostic (4.43e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-2)" 0.4 1.1 1.3 3.2 1.2 1.0 0.3 1.6 1.5 0.5 1.1 9.2 17.9 0.5 0.3 0.5 0.3 0.5 0.1 1.1 1.3 133.9 62.1 0.2 4.0 0.7 0.6 0.1 0.6 2.2 0.3 0.2 0.8 0.5 6.8 0.4 4.6 0.1 34.2 0.4 13.4 0.7 0.4 1.6 1.8 0.7 0.9 2.1 0.5 6.1 4.1 0.8 0.1 1.2 7.7 6.3 0.5 0.3 0.1 0.8 0.2 1.3 1.4 0.8 0.5 36.7 5.1 0.1 0.2 0.9 0.2 0.2 0.0 0.0 0.9 7.6 0.1 5.2 5.1 92.6 0.9 4.0 0.2 0.9 0.4 2.4 0.0 0.6 0.7 0.1 0.1 10.3 1.9 8.6 0.2 4.0 8.1 6.5 3.7 0.1 0.0 22.3 0.2 2.2 1.5 1.1 10.9 0.4 1.3 0.4 1.5 8.2 1.1 0.3 0.3 2.1 0.1 0.3 6.1 5.0 0.4 0.1 0.2 1.2 0.3 0.2 2.1 0.3 2.6 4.1 4.5 2.4 0.2 2.7 8.4 5.0 1.4 0.5 0.2 0.4 6.4 2.0 1.3 1.2 1.6 1.5 1.1 1.3 0.7 0.6 0.8 0.4 0.9 1.2 0.2 0.0 0.0 1.0 5.9 0.3 1.7 0.5 0.0 1.3 0.5 0.9 0.6 2.8 0.3 3.7 0.0 0.9 0.5 7.4 31.3 1.1 9.4 1.2 1.1 0.6 1.2 2.1 1.9 0.9 0.8 0.7 5.1 2.1 0.0 1.4 1.8 42.5 1.1 3.3 2.2 9.6 2.0 2.9 0.8 4.2 0.3 2.0 1.8 3.7 1.9 1.0 5.2 0.5 0.4 2.3 6.0 0.0 2.0 1.7 27.0 306.8 1.4 2.4 0.0 4.7 0.5 1.6 3.5 1.2 0.6 0.8 5.0 3.4 18.9 3.0 AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 94.5;Collecting duct cells: 156.3;Ductal cells: 91.2;Pancreatic endocrine cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 205.3;EFO-21: 236.9;HaCaT: 210.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 20000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" 11.4 2.7 8.7 4.3 5.5 2.0 14.7 0.1 13.9 14.4 8.9 10.9 7.9 13.7 1.8 15.6 14.6 7.3 9.9 5.8 0.0 44.0 13.3 19.8 1.6 16.0 1.4 5.5 28.0 3.9 8.3 5.1 6.1 14.4 1.5 0.8 24.8 8.2 4.2 16.5 9.6 2.9 2.2 6.3 13.4 9.7 7.9 2.6 34.7 2.0 1.6 16.2 11.6 9.9 124.3 75.1 11.1 42.7 2.4 3.0 122.1 61.4 19.6 39.7 24.5 60.6 205.3 2.3 236.9 9.6 19.3 210.1 4.1 75.6 4.7 4.4 28.6 0.2 102.1 54.2 17.1 1.8 23.1 10.5 32.2 12.6 27.7 55.9 7.2 1.7 25.7 0.7 3.5 93.0 0.8 17.6 28.4 39.7 54.5 20.1 27.0 18.5 70.0 51.4 2.4 25.9 124.8 129.1 121.9 12.7 114.8 7.4 107.8 47.7 169.0 6.4 50.6 1.2 0.6 3.5 30.4 10.8 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 5.5 0.1 13.9 5.8 0.0 16.0 1.4 6.1 2.2 7.9 9.9 27.4 25.6 8.8 15.0 2.2 15.0 9.2 94.5 19.9 1.4 32.7 39.2 3.1 61.5 42.0 156.3 8.4 1.6 0.9 29.9 1.9 91.2 0.4 37.2 14.0 29.0 6.7 1.7 23.1 16.9 4.8 8.7 17.9 62.7 2.5 7.2 21.8 13.1 4.1 5.0 7.8 11.6 36.7 2.9 10.1 1.0 5.6 4.3 24.9 12.2 15.6 10.5 0.0 15.1 29.6 87.3 17.7 2.6 0.6 22.3 18.1 16.0 33.0 5.3 6.6 3.3 23.3 0.8 11.4 11.7 6.0 1.2 2.9 2.3 18.3 21.2 AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 262.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 71.0;hTERT-HME1: 73.8;OE19: 61.2;RT4: 63.2" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB005072: AB_633731, HPA029722: AB_10599189, HPA029723: AB_10599025" "unprognostic (1.29e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (4.32e-2)" "unprognostic (9.98e-2)" "unprognostic (1.24e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-2)" "unprognostic (9.45e-2)" 22.3 15.0 1.4 25.8 2.7 44.1 19.5 1.4 2.8 14.5 2.3 13.7 16.4 8.8 7.0 17.4 10.5 33.7 9.5 1.9 1.3 7.1 45.0 37.6 15.4 5.4 1.9 6.9 5.8 6.6 3.0 17.7 3.9 11.0 16.3 4.0 10.5 11.2 2.2 22.0 14.5 15.2 2.8 18.7 25.2 2.9 2.7 9.7 12.7 6.5 19.8 49.5 15.0 5.8 8.2 6.6 2.6 0.0 19.2 13.1 1.2 16.5 23.9 7.5 10.8 8.2 17.5 0.0 5.0 24.4 29.7 21.8 1.6 15.1 19.7 0.4 3.6 4.8 8.1 7.3 35.5 8.1 11.5 18.1 71.0 28.8 73.8 33.8 25.3 0.0 0.7 0.2 34.3 4.2 0.0 12.6 2.1 61.2 10.3 0.0 0.0 0.3 23.5 63.2 2.4 0.0 12.4 13.0 12.5 19.0 9.4 2.7 4.3 3.1 0.1 40.7 0.0 3.3 0.1 0.0 51.6 30.6 51.9 0.8 5.6 4.2 0.5 2.6 0.7 0.6 1.7 1.0 6.9 0.7 0.9 0.7 0.6 2.1 1.0 1.6 2.1 1.7 1.4 2.7 1.4 2.8 1.9 1.3 5.4 1.9 3.9 2.8 2.7 5.8 78.3 150.6 76.2 1.6 15.2 75.3 47.6 67.9 104.2 37.0 23.4 30.0 14.7 34.3 84.9 7.3 8.4 3.3 13.6 23.9 0.0 19.3 6.2 39.1 8.4 78.1 5.4 8.6 18.0 15.7 1.8 57.0 56.1 78.8 133.1 0.6 52.1 48.3 24.4 43.7 39.2 12.9 30.5 88.4 262.6 3.2 3.7 107.1 71.2 8.4 70.1 0.9 5.2 1.5 40.6 33.3 19.8 2.6 16.7 48.6 9.9 6.8 51.3 6.1 6.6 14.8 37.8 2.8 2.2 38.3 89.2 21.5 54.7 3.3 19.3 116.1 AKTIP "FLJ13258, FTS" ENSG00000166971 "AKT interacting protein" Q9H8T0 16 53491040-53504411 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 168.3;Late spermatids: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041794, HPA046300" Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA041794: AB_2677677, HPA046300: AB_2679619" "unprognostic (2.08e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-2)" "unprognostic (5.44e-2)" "unprognostic (2.62e-2)" "unprognostic (9.90e-2)" "unprognostic (1.72e-2)" "unprognostic (3.41e-3)" "unprognostic (2.45e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "prognostic favorable (1.18e-14)" "unprognostic (2.39e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-1)" "unprognostic (1.31e-1)" 29.3 20.5 46.9 15.7 48.9 32.1 24.7 47.8 55.7 24.5 42.0 30.2 15.5 22.3 31.6 33.2 21.4 17.4 55.3 50.9 47.2 37.1 31.8 24.4 22.5 51.5 46.9 30.4 17.3 44.9 29.0 30.2 52.8 24.7 17.8 76.9 20.5 31.0 134.9 26.9 20.0 25.7 47.6 15.5 21.2 44.0 47.5 13.2 31.7 81.4 24.2 25.1 26.1 48.9 40.2 25.7 17.2 22.7 22.8 17.2 50.5 24.7 18.6 21.5 5.3 35.0 20.6 6.6 14.9 25.4 16.2 34.0 14.9 20.0 28.8 9.7 23.6 1.9 13.6 28.1 29.6 9.2 17.1 14.6 55.1 21.4 18.4 31.2 37.1 13.4 3.6 14.1 19.2 31.2 8.0 13.7 11.9 19.2 24.6 9.6 28.5 30.3 28.4 33.2 13.5 16.8 14.9 52.4 22.4 22.9 46.7 5.7 35.2 23.1 25.1 15.2 24.4 20.6 19.6 13.5 24.9 8.1 15.0 22.3 4.5 11.0 32.4 3.4 19.5 9.1 31.1 33.9 2.0 13.7 47.7 39.3 29.3 27.1 3.4 3.0 46.4 19.1 46.9 48.9 47.8 55.7 50.9 47.2 51.5 46.9 52.8 47.6 47.5 48.9 41.9 25.6 15.4 11.8 9.3 7.0 15.1 29.0 5.7 28.4 17.9 11.9 32.2 17.2 25.4 23.9 16.7 80.3 13.6 15.0 82.2 29.8 168.3 11.2 7.1 22.2 6.0 3.6 19.4 20.5 44.3 16.4 8.2 12.9 3.8 9.6 26.0 26.3 13.3 21.9 20.2 6.5 44.7 7.0 5.6 325.9 14.0 6.2 23.2 7.5 8.0 58.8 28.8 8.5 21.5 20.6 6.0 38.4 12.2 15.0 36.2 38.2 22.0 27.3 6.6 22.1 22.2 16.1 40.4 11.2 12.8 77.3 28.7 8.4 11.5 19.0 ALDH1A2 RALDH2 ENSG00000128918 "Aldehyde dehydrogenase 1 family member A2" O94788 15 57953424-58497866 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 82.2;fallopian tube: 74.5" "Group enriched" "Detected in many" 4 "Early spermatids: 115.7;Endometrial stromal cells: 142.2;Late spermatids: 48.7;Microglial cells: 42.2;Spermatocytes: 78.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 13.1;hippocampal formation: 8.4" "Immune cell enriched" "Detected in some" 15 "neutrophil: 32.6" "Lineage enriched" "Detected in single" 62 "granulocytes: 32.6" "Group enriched" "Detected in some" 5 "AN3-CA: 402.4;HEK 293: 128.8;JURKAT: 387.2;K-562: 316.2;MOLT-4: 408.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010022 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA010022: AB_1844723" "unprognostic (1.11e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" "unprognostic (1.44e-2)" "unprognostic (1.16e-2)" "unprognostic (1.04e-4)" "unprognostic (1.08e-1)" "unprognostic (9.03e-3)" "unprognostic (6.92e-3)" "unprognostic (5.48e-2)" "unprognostic (6.19e-2)" "unprognostic (2.57e-3)" "unprognostic (3.18e-2)" "unprognostic (4.95e-2)" "unprognostic (1.99e-2)" "unprognostic (1.80e-3)" 21.3 3.9 1.9 2.9 1.4 4.0 5.9 2.1 13.1 52.3 3.4 1.7 0.7 82.2 7.8 2.4 74.5 24.0 28.4 8.4 0.9 19.5 2.6 7.8 0.6 1.7 1.6 24.0 3.2 29.8 14.6 5.2 1.9 21.0 0.7 6.0 2.0 53.3 10.7 1.7 1.3 31.9 1.8 4.3 0.7 57.6 2.5 2.8 1.4 3.0 0.4 4.0 12.9 1.1 1.2 0.0 0.0 402.4 0.0 0.0 0.1 0.0 5.7 0.6 1.3 0.0 0.3 0.4 3.9 0.0 0.1 1.0 11.8 0.0 0.7 0.0 128.8 0.0 2.7 0.7 0.3 0.0 3.0 2.3 0.0 0.0 0.0 0.0 21.4 387.2 316.2 0.0 0.0 0.0 408.5 0.1 0.7 11.2 19.6 0.0 0.8 0.0 70.7 2.0 0.8 0.1 0.4 0.4 1.9 0.4 0.2 0.1 0.9 0.3 1.0 3.8 0.0 0.3 0.0 0.0 0.2 0.2 0.1 2.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.3 0.0 0.0 0.0 1.9 1.4 2.1 13.1 8.4 0.9 1.7 1.6 1.9 1.8 2.5 1.1 13.1 6.4 13.9 0.0 0.0 0.6 1.9 0.2 0.0 1.1 1.1 0.9 2.4 20.0 3.4 7.3 0.0 0.3 0.1 5.2 13.7 11.6 115.7 6.8 142.2 7.6 0.0 0.0 5.8 0.4 0.3 17.6 0.0 3.6 1.3 0.3 10.8 17.4 2.2 0.0 9.6 0.1 0.0 1.6 0.8 48.7 5.3 3.0 1.8 42.2 0.7 10.1 0.0 0.0 1.2 0.7 0.3 5.3 0.0 1.3 0.3 0.3 1.4 0.3 0.0 8.3 3.3 78.9 14.7 0.2 0.4 0.5 1.0 0.1 0.7 1.3 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 20.3;Ductal cells: 37.0;Endometrial ciliated cells: 24.0;Glandular and luminal cells: 50.3;Granulosa cells: 64.3;Proximal tubular cells: 28.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "AF22: 138.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" 28.8 205.4 4.6 2.0 6.3 0.6 26.6 3.5 2.9 4.9 4.8 8.2 3.7 26.4 13.4 2.0 26.2 10.7 2.2 3.1 5.4 21.1 4.5 34.0 0.9 3.6 2.1 74.4 64.3 2.3 8.6 9.6 2.7 6.5 6.5 0.4 5.4 2.6 1.5 17.3 7.7 9.9 1.8 12.3 17.3 35.5 5.1 1.7 10.4 0.5 1.6 4.7 5.3 4.8 0.0 0.0 138.8 0.1 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.4 1.3 0.0 0.0 0.2 0.5 0.0 0.0 0.5 0.3 0.0 0.1 0.7 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.3 0.7 0.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.1 4.6 6.3 3.5 2.9 3.1 5.4 3.6 2.1 2.7 1.8 5.1 4.8 2.5 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 14.6 20.3 0.0 0.0 0.0 1.8 0.0 0.1 1.4 0.0 3.9 37.0 0.0 24.0 6.3 4.5 0.0 0.0 0.0 0.7 0.1 3.1 0.0 50.3 0.0 64.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.6 0.9 0.0 0.0 ALKBH7 "MGC10974, SPATA11" ENSG00000125652 "AlkB homolog 7" Q9BT30 19 6372794-6375250 "Predicted intracellular proteins" Necrosis "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 517.8" "Group enriched" "Detected in all" 4 "Early spermatids: 3004.6;Late spermatids: 8717.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008539, HPA039571, HPA039872" Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA008539: , HPA039571: AB_2676577, HPA039872: AB_10697710" "unprognostic (5.38e-2)" "unprognostic (3.58e-2)" "unprognostic (2.20e-1)" "unprognostic (1.15e-2)" "unprognostic (7.79e-2)" "unprognostic (3.56e-3)" "unprognostic (1.06e-1)" "unprognostic (1.35e-1)" "unprognostic (3.02e-1)" "unprognostic (6.83e-2)" "unprognostic (1.72e-3)" "unprognostic (1.54e-1)" "prognostic favorable (7.83e-6)" "unprognostic (7.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" 48.9 64.5 59.8 19.2 62.3 31.1 51.3 65.7 74.2 54.6 69.5 72.5 65.8 48.4 14.6 66.1 55.4 19.2 157.2 56.6 61.3 86.0 152.9 40.4 26.9 64.0 61.3 68.8 112.3 44.9 67.5 14.3 61.0 70.1 20.0 15.8 65.2 30.5 154.4 61.0 61.5 12.8 63.6 46.6 68.4 517.8 61.6 28.1 73.0 67.4 15.9 52.1 51.6 68.5 28.9 25.2 21.4 37.1 11.8 32.7 30.9 20.5 18.0 18.1 19.1 44.0 18.3 42.1 68.4 26.2 12.8 22.1 9.6 17.1 3.5 40.9 38.9 24.5 17.6 41.4 34.5 12.4 31.3 37.6 33.8 15.7 12.3 17.5 22.5 40.7 26.2 80.0 13.9 58.3 63.5 42.6 30.8 33.9 106.1 46.6 13.4 84.2 20.4 22.1 30.3 46.3 13.8 36.1 76.4 10.1 41.0 44.7 20.3 18.0 25.0 66.9 20.1 129.2 98.1 27.7 33.9 41.9 15.9 38.3 106.4 17.3 52.7 91.6 72.9 113.4 91.4 72.5 127.6 103.0 137.4 111.1 64.4 66.1 72.0 143.9 85.7 91.5 59.8 62.3 65.7 74.2 56.6 61.3 64.0 61.3 61.0 63.6 61.6 68.5 84.8 60.9 74.4 3.3 109.0 83.7 154.4 129.1 160.5 93.1 221.6 335.4 106.3 112.9 83.9 66.2 66.7 97.6 79.3 516.1 313.1 110.1 3004.6 76.1 73.0 84.8 220.4 54.0 2.4 245.2 149.6 88.0 77.5 85.1 66.0 108.3 113.2 302.0 196.8 42.1 3.5 400.4 71.2 168.6 96.2 8717.7 103.2 128.6 133.4 1.9 192.6 166.1 69.0 3.0 9.3 116.0 528.2 88.8 121.0 121.1 856.4 433.6 52.7 152.4 92.1 97.2 104.1 1180.3 76.7 171.2 100.6 108.9 87.4 143.4 410.5 215.6 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 AMOT KIAA1071 ENSG00000126016 Angiomotin Q4VCS5 X 112774503-112840889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 145.6;tongue: 53.5" "Cell type enhanced" "Detected in many" "Astrocytes: 57.5;Collecting duct cells: 29.5;Cytotrophoblasts: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 22.5;HAP1: 25.1;OE19: 21.2;SuSa: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067290, HPA067853" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Cell Junctions" Nucleoplasm "HPA067290: AB_2685819, HPA067853: AB_2732773" "unprognostic (1.08e-2)" "unprognostic (5.51e-2)" "unprognostic (2.38e-2)" "unprognostic (3.36e-1)" "unprognostic (3.20e-1)" "unprognostic (8.95e-2)" "unprognostic (3.82e-2)" "prognostic favorable (3.94e-4)" "unprognostic (4.46e-2)" "unprognostic (3.79e-1)" "unprognostic (2.17e-1)" "unprognostic (5.60e-2)" "prognostic favorable (4.21e-9)" "unprognostic (9.54e-2)" "unprognostic (2.59e-2)" "unprognostic (4.50e-2)" "unprognostic (6.44e-2)" 4.3 1.6 29.0 1.3 24.7 0.3 6.5 23.4 21.9 9.2 0.6 3.5 2.9 4.9 145.6 4.0 12.2 2.8 4.0 23.7 31.6 10.4 2.1 2.7 0.8 32.8 34.4 5.7 2.3 14.3 7.2 20.7 24.1 6.3 4.3 1.7 6.9 25.7 39.0 2.3 3.7 3.2 20.6 1.5 3.0 2.3 36.4 4.4 3.8 53.5 1.0 2.8 4.1 18.2 4.3 0.0 22.5 1.0 0.5 0.5 8.8 0.7 0.0 0.0 0.0 10.5 0.8 0.5 4.7 3.5 0.0 8.4 25.1 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.2 0.0 1.1 0.2 0.0 5.1 0.6 4.9 0.2 0.4 0.0 0.0 0.6 0.4 6.8 0.3 10.5 21.2 0.1 8.4 6.6 0.1 11.2 11.0 0.0 8.0 0.1 0.0 9.8 34.9 0.8 0.2 0.1 2.9 6.8 0.0 9.4 0.7 0.0 0.0 1.0 0.1 6.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 29.0 24.7 23.4 21.9 23.7 31.6 32.8 34.4 24.1 20.6 36.4 18.2 2.2 3.2 2.0 57.5 0.9 1.8 2.7 2.5 2.8 1.1 9.7 6.9 2.0 1.5 7.2 29.5 0.0 46.2 1.1 4.9 1.9 5.1 0.2 7.2 6.3 3.7 15.8 0.4 8.9 1.9 3.8 7.2 4.1 7.1 0.0 1.5 4.2 4.0 6.2 0.0 2.0 7.2 6.1 1.6 2.1 0.5 6.8 1.0 3.6 17.8 1.7 4.9 4.1 2.0 3.5 3.2 5.6 6.4 0.0 6.6 4.7 16.8 10.1 0.5 6.6 3.9 4.0 0.4 3.2 3.0 1.1 15.9 0.9 0.8 7.3 2.5 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Group enriched" "Detected in some" 6 "Plasma cells: 43.8;Skeletal myocytes: 13.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "U-266/70: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 0.1 0.1 0.0 0.5 0.0 0.3 3.0 0.0 0.0 0.2 0.0 5.6 16.4 0.2 0.0 5.8 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.0 3.5 5.5 0.0 4.4 0.9 559.2 0.0 7.5 0.1 0.0 1.6 3.7 0.1 0.0 0.4 0.1 211.4 2.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.8 1.9 0.0 0.0 0.0 3.0 4.2 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 160.1;Hofbauer cells: 208.8;Inhibitory neurons: 214.5;Oligodendrocytes: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" 9.9 10.6 22.1 6.6 23.8 8.0 9.9 33.9 29.3 5.5 26.6 12.8 16.8 7.1 4.9 7.4 7.7 9.4 32.2 22.5 25.5 8.1 21.4 7.1 8.5 25.3 28.2 16.0 15.2 19.2 22.8 8.5 25.1 32.7 11.4 25.1 14.3 9.2 40.9 20.3 15.0 8.5 24.9 6.8 7.3 1.9 26.8 11.5 10.7 37.6 14.1 7.3 7.4 28.8 7.2 5.4 6.7 1.1 13.8 32.3 3.2 6.8 13.7 2.6 2.7 4.3 9.0 16.9 15.7 9.4 6.2 4.6 4.6 7.5 3.0 6.7 11.3 0.4 47.8 11.6 4.6 4.1 1.3 10.2 13.0 8.1 9.2 9.2 5.5 12.3 3.5 35.2 8.7 9.6 6.9 13.3 2.6 9.5 6.0 9.8 3.3 15.3 0.0 2.3 16.4 4.5 33.3 5.3 7.5 6.1 0.3 1.5 5.4 6.9 6.9 11.5 12.6 9.2 9.3 13.0 23.8 15.1 29.0 0.6 0.2 0.0 1.4 0.4 2.3 1.5 2.9 2.3 0.3 1.6 3.3 1.5 0.3 0.3 0.9 0.3 4.6 0.4 22.1 23.8 33.9 29.3 22.5 25.5 25.3 28.2 25.1 24.9 26.8 28.8 50.1 25.6 19.1 64.6 15.4 25.2 79.1 33.7 40.9 58.0 29.7 15.5 73.4 7.2 10.8 7.3 127.2 76.4 21.1 58.2 5.9 1.7 1.2 7.1 14.9 25.4 41.8 69.9 160.1 11.8 6.1 25.6 8.2 16.9 17.7 9.8 12.5 32.7 208.8 20.2 214.5 37.7 8.2 89.3 29.9 1.9 5.0 42.6 10.6 106.8 3.4 20.1 21.6 95.5 261.5 6.8 31.4 31.6 14.7 55.4 44.6 10.2 6.4 50.1 0.0 32.8 12.3 2.3 7.2 10.1 10.7 42.0 25.9 8.6 37.3 22.3 ANKRD34C ENSG00000235711 "Ankyrin repeat domain 34C" P0C6C1 15 79293285-79298235 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 5.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 3.0;Inhibitory neurons: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "SCLC-21H: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045329 Approved Mitochondria NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045329: AB_2679291" "unprognostic (3.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.42e-3)" "unprognostic (5.31e-2)" "unprognostic (2.48e-1)" 0.1 0.1 1.4 0.0 0.5 0.0 0.0 2.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 3.0 0.0 0.0 0.1 0.0 2.2 2.8 0.0 0.2 0.0 0.7 0.0 3.4 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 2.0 1.9 0.4 3.0 2.2 2.8 3.4 0.2 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD65 ENSG00000235098 "Ankyrin repeat domain 65" E5RJM6 1 1418420-1421769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.0;Glandular and luminal cells: 88.4;Respiratory ciliated cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "myeloid DC: 3.5;plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 23 "dendritic cells: 7.8" "Group enriched" "Detected in some" 8 "Hep G2: 35.9;RT4: 34.5;SCLC-21H: 46.3" "Not detected" "Not detected" HPA065720 Enhanced Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA065720: AB_2685545" "unprognostic (2.17e-2)" "unprognostic (2.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.77e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.64e-1)" "unprognostic (4.39e-1)" "unprognostic (1.16e-1)" "unprognostic (4.43e-2)" "unprognostic (5.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.81e-2)" "unprognostic (8.04e-2)" "unprognostic (2.76e-2)" 6.0 1.0 24.6 3.2 29.5 0.2 10.3 25.6 25.9 8.8 18.5 14.2 2.3 7.6 5.9 15.6 36.7 2.9 4.1 22.0 25.2 6.0 1.5 11.2 9.1 31.0 28.5 8.5 15.2 1.4 2.3 6.9 29.4 19.9 1.7 2.5 16.1 21.9 3.1 7.0 6.3 4.0 24.0 1.6 9.9 7.3 25.7 7.8 4.3 3.3 7.2 21.1 9.4 34.8 1.0 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.5 0.9 0.0 4.5 0.3 4.3 0.0 0.5 0.4 0.0 0.0 35.9 0.8 0.1 0.0 0.4 5.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 0.1 0.0 0.3 4.6 0.0 0.0 34.5 46.3 0.5 0.2 0.0 0.1 0.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.3 0.0 0.3 0.0 0.0 0.0 7.8 0.0 0.2 24.6 29.5 25.6 25.9 22.0 25.2 31.0 28.5 29.4 24.0 25.7 34.8 11.8 22.4 29.0 5.5 0.1 2.2 12.9 14.1 13.1 8.5 5.9 32.5 0.7 14.3 20.1 1.8 0.0 26.0 0.0 0.0 9.8 19.0 0.0 65.0 20.5 11.7 1.8 2.7 4.4 30.7 0.8 13.3 3.1 88.4 8.8 2.9 1.4 0.8 2.2 8.4 2.0 0.0 14.2 1.0 3.3 0.9 20.8 1.5 3.6 1.0 1.2 16.6 0.0 3.5 20.5 11.0 0.1 29.0 0.1 6.3 0.0 0.5 51.8 3.1 0.0 25.7 3.6 0.3 0.3 10.7 3.1 16.8 1.1 0.7 0.0 10.8 ANKS1A "ANKS1, KIAA0229" ENSG00000064999 "Ankyrin repeat and sterile alpha motif domain containing 1A" Q92625 6 34889255-35091406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Inhibitory neurons: 160.5;Microglial cells: 168.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SCLC-21H: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036768, HPA036769" Approved Approved Nucleoplasm,Cytosol NA NA 17000 "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA036768: AB_10670923, HPA036769: AB_10672473" "unprognostic (3.75e-2)" "unprognostic (2.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.79e-3)" "unprognostic (5.73e-2)" "prognostic favorable (7.48e-4)" "unprognostic (1.18e-3)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "prognostic favorable (8.05e-5)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.23e-2)" "unprognostic (7.80e-2)" 15.0 19.1 15.2 8.0 13.9 5.7 15.0 16.4 15.8 10.9 13.8 29.0 10.5 10.7 7.4 15.4 20.1 10.0 18.6 12.7 13.4 13.1 10.7 18.8 9.3 15.6 17.0 17.4 9.4 16.4 8.4 27.8 17.4 11.7 9.0 22.9 9.2 15.4 20.1 15.6 14.3 14.3 14.0 23.0 14.8 16.5 22.1 7.6 13.8 9.5 5.7 27.2 13.1 11.9 15.4 7.3 14.8 14.2 6.5 6.4 22.3 6.0 6.7 7.2 8.7 18.4 9.7 10.4 10.0 6.4 13.1 15.7 17.4 17.6 8.3 8.0 21.9 7.3 9.2 13.7 4.0 11.8 6.7 7.4 14.9 9.3 12.3 7.7 15.9 10.7 12.6 4.4 6.4 10.0 7.4 12.8 10.7 20.3 8.4 8.9 8.3 10.6 14.5 27.9 58.5 14.8 10.3 14.1 43.7 18.1 11.1 13.0 13.9 7.3 9.2 7.6 8.9 6.7 10.9 5.5 5.6 16.8 20.3 0.0 0.6 0.5 0.2 0.9 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.2 1.1 0.2 1.5 1.1 0.3 0.4 15.2 13.9 16.4 15.8 12.7 13.4 15.6 17.0 17.4 14.0 22.1 11.9 48.2 80.1 11.4 54.2 4.4 12.1 9.1 4.2 4.0 28.8 11.3 14.4 25.3 11.5 8.3 12.9 64.6 8.9 5.5 17.2 0.0 7.3 12.7 32.1 7.4 31.7 13.2 5.7 94.0 5.9 7.5 10.0 13.3 35.6 2.5 17.2 47.5 6.6 11.9 8.4 160.5 11.0 18.3 29.2 10.9 11.3 12.8 18.9 5.4 168.6 8.1 21.7 10.3 90.5 75.9 10.2 7.6 30.1 6.4 13.3 10.0 7.0 29.0 45.4 19.7 10.3 13.5 6.9 5.9 8.5 20.5 12.4 4.8 5.9 9.2 14.9 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 AOPEP "AP-O, APO, C90RF3, C9orf3, FLJ14675" ENSG00000148120 "Aminopeptidase O (putative)" Q8N6M6 9 94726604-95087159 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 148.2;Cytotrophoblasts: 65.9;Extravillous trophoblasts: 43.7;Syncytiotrophoblasts: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004633, HPA072729" Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Cell Junctions" "HPA004633: AB_1078362, HPA072729: AB_2686553" "unprognostic (4.25e-2)" "unprognostic (1.07e-3)" "unprognostic (6.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (2.75e-2)" "unprognostic (9.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.80e-1)" "prognostic favorable (6.33e-5)" "unprognostic (2.31e-1)" "unprognostic (2.56e-1)" "unprognostic (3.29e-2)" "unprognostic (3.37e-2)" 5.6 6.6 11.8 4.9 20.4 2.2 7.0 16.9 16.3 8.1 23.8 6.9 4.3 18.5 8.3 16.9 10.3 12.1 29.4 15.9 15.5 7.2 7.6 10.4 2.2 23.0 15.7 8.1 11.2 16.3 5.7 24.3 20.7 14.3 5.8 4.7 12.2 15.2 30.5 38.6 5.0 15.8 11.1 5.0 5.7 6.0 15.4 2.6 11.2 15.3 5.6 7.7 6.8 40.5 6.8 27.6 3.3 5.3 3.4 3.8 12.4 6.4 3.0 6.3 4.1 6.3 8.7 2.1 5.3 9.8 8.7 24.8 5.7 6.1 3.4 13.2 4.9 2.0 30.1 5.8 6.1 1.8 1.4 4.4 23.7 5.5 4.1 17.7 3.5 3.3 3.4 3.0 11.4 10.1 2.8 2.3 4.4 7.8 10.7 4.2 9.4 2.7 11.0 6.4 6.6 9.7 11.2 9.4 2.5 8.5 10.8 1.5 2.7 2.9 2.8 10.8 3.4 2.5 3.6 1.0 9.8 1.7 4.8 0.0 1.4 0.9 1.4 1.0 0.8 0.9 1.1 1.2 2.2 2.2 0.8 1.0 0.5 1.4 0.7 2.1 0.8 0.7 11.8 20.4 16.9 16.3 15.9 15.5 23.0 15.7 20.7 11.1 15.4 40.5 20.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.2 0.0 0.0 0.0 0.0 65.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 43.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 88.2 0.2 0.0 0.0 0.0 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 749.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 87.6 300.5 0.6 3.2 2.9 0.5 50.2 0.1 2.4 17.9 3.6 12.0 0.8 10.8 12.3 8.2 48.2 9.9 14.9 1.1 1.5 103.2 891.0 19.5 4.7 1.3 1.0 48.0 85.0 1.3 2.8 1.7 1.2 22.3 4.5 0.5 15.3 28.3 12.9 20.1 12.7 7.1 0.5 4.1 14.3 19.4 4.0 2.0 17.7 11.0 1.5 38.6 17.7 3.6 0.6 0.2 0.0 0.0 377.3 191.5 0.2 6.6 12.2 5.4 9.7 0.0 0.1 0.1 0.5 8.4 2.3 0.2 0.1 18.6 22.0 0.2 0.6 0.0 4.6 20.7 25.4 0.9 0.0 78.2 4.6 26.1 81.2 5.4 0.2 0.2 0.2 0.1 18.3 0.5 0.0 0.1 8.0 0.1 5.2 0.0 0.5 0.1 0.2 0.2 0.4 0.3 4.8 0.0 0.3 0.4 0.1 0.2 31.9 13.8 11.2 0.2 2.5 0.2 0.1 2.6 10.7 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.1 2.4 1.1 1.5 1.3 1.0 1.2 0.5 4.0 3.6 1.0 3.2 1.1 0.7 3.6 1.8 0.5 1.2 1.2 0.1 0.2 0.3 0.9 17.2 0.1 3.7 0.0 0.1 0.0 0.1 11.7 0.7 0.8 0.4 3.0 2.6 3.0 37.5 0.9 26.2 0.2 22.9 0.0 8.2 0.0 0.1 15.4 749.1 0.4 0.0 2.5 0.1 2.0 19.8 3.6 4.4 74.0 1.7 3.6 1.0 0.0 0.6 0.0 5.0 6.9 11.5 0.0 82.0 0.0 7.5 0.1 162.2 0.1 0.1 0.0 5.3 3.0 0.8 1.3 0.1 1.6 0.0 2.0 2.3 0.1 0.4 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOL5 APOLV ENSG00000128313 "Apolipoprotein L5" Q9BWW9 22 35717872-35729483 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.4;tongue: 2.0" "Cell type enhanced" "Detected in single" "Early spermatids: 1.1" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "U-698: 1.7" NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.23e-1)" "unprognostic (7.61e-4)" "unprognostic (9.34e-2)" "unprognostic (1.39e-2)" "unprognostic (3.23e-1)" "unprognostic (4.18e-2)" "unprognostic (4.37e-5)" "unprognostic (3.23e-2)" "unprognostic (2.78e-2)" "unprognostic (2.94e-2)" "unprognostic (1.59e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.9;brain: 92.8" "Cell type enhanced" "Detected in many" "Astrocytes: 285.4;Late spermatids: 167.5;Oligodendrocytes: 781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.7;hTCEpi: 12.7;MOLT-4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Actin filaments" "HPA035925: AB_10672075" "unprognostic (2.97e-2)" "unprognostic (8.62e-2)" "unprognostic (3.43e-3)" "unprognostic (1.04e-1)" "unprognostic (8.86e-2)" "unprognostic (2.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-3)" "unprognostic (2.96e-1)" "unprognostic (4.48e-2)" "unprognostic (4.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" 4.5 2.2 28.9 10.0 70.4 39.9 5.1 19.9 39.5 3.5 0.0 5.3 8.9 3.3 3.8 13.1 3.3 9.3 1.5 24.5 21.5 3.7 9.4 13.4 15.7 34.1 38.8 1.5 7.0 5.4 2.9 3.5 32.6 2.2 5.6 1.4 4.6 2.9 0.7 16.1 8.9 4.3 18.3 11.5 6.1 6.2 32.1 24.6 23.2 0.8 11.0 9.9 6.3 92.8 8.6 0.7 0.8 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 4.2 13.7 4.1 3.2 0.4 0.0 3.2 1.3 6.7 0.0 0.0 7.6 0.1 2.9 0.2 1.6 5.5 0.0 0.4 12.7 0.0 2.7 4.9 0.0 11.1 0.2 0.7 0.0 3.6 12.8 4.5 1.0 6.0 2.6 6.5 0.0 4.7 9.3 8.7 7.3 0.0 0.4 2.1 2.7 0.4 5.6 1.6 0.0 2.3 7.5 0.0 1.1 0.0 0.0 8.0 0.9 6.1 1.9 0.0 0.5 0.0 3.8 1.8 3.5 1.8 2.1 2.7 0.3 0.9 0.7 1.9 0.4 6.7 4.7 1.2 1.1 0.6 28.9 70.4 19.9 39.5 24.5 21.5 34.1 38.8 32.6 18.3 32.1 92.8 18.6 153.8 23.3 285.4 46.1 39.1 32.9 13.5 21.6 0.8 11.2 7.0 2.1 17.2 33.2 7.3 0.0 0.2 100.4 15.5 7.9 7.9 123.6 31.4 3.0 15.8 3.0 8.6 140.8 10.0 0.4 9.4 20.4 50.0 9.5 5.9 3.3 4.2 8.7 0.0 29.9 11.3 6.1 33.2 24.9 167.5 2.8 35.1 5.4 40.3 26.7 5.4 95.8 161.4 781.2 21.5 23.3 0.7 43.0 30.0 17.4 5.8 18.0 1.2 0.0 8.1 3.6 4.2 3.0 37.0 67.5 0.8 90.7 0.1 6.9 44.1 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 99.8" "Group enriched" "Detected in many" 4 "Astrocytes: 1364.3;Microglial cells: 905.0" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.9;memory B-cell: 47.3;naive B-cell: 36.8;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.3;dendritic cells: 12.7;monocytes: 15.9" "Cell line enhanced" "Detected in many" "ASC diff: 109.0;ASC TERT1: 65.5;HHSteC: 63.6;HUVEC TERT2: 121.9;RPTEC TERT1: 67.2;TIME: 87.0;U-138 MG: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" 14.6 2.2 6.5 7.5 5.1 18.7 9.2 6.2 5.8 5.5 3.9 7.4 7.3 9.4 4.6 6.1 4.1 10.9 27.3 5.7 6.6 99.8 9.5 15.7 10.5 15.7 11.5 5.5 30.1 8.1 5.4 22.4 17.2 5.4 6.1 8.4 10.6 7.2 10.2 7.0 10.3 14.1 12.1 16.4 26.0 3.4 10.4 7.5 27.8 7.7 15.5 9.1 5.6 19.1 3.0 6.2 4.4 0.1 109.0 65.5 4.8 21.5 28.5 5.2 8.4 0.1 0.0 2.8 7.4 48.8 6.4 0.0 0.2 9.0 11.0 0.0 1.2 3.6 0.6 0.2 63.6 0.4 0.0 48.4 0.9 10.3 4.7 23.9 121.9 0.0 6.6 0.4 46.1 0.0 0.1 0.0 0.3 1.5 11.3 0.6 22.4 11.8 67.2 0.0 2.3 2.3 2.5 3.5 7.8 4.7 0.4 0.2 87.0 59.9 1.2 4.4 0.3 0.3 0.0 3.9 10.1 2.2 19.9 0.0 15.9 0.0 0.0 3.0 0.0 47.3 0.0 0.0 3.8 36.8 0.0 0.0 5.5 0.0 2.3 12.7 0.0 3.1 6.5 5.1 6.2 5.8 5.7 6.6 15.7 11.5 17.2 12.1 10.4 19.1 14.0 57.7 28.8 1364.3 142.1 8.2 3.9 35.6 10.2 6.6 1.2 4.7 26.4 47.1 18.3 46.0 6.2 54.8 9.9 1.0 226.9 9.4 30.5 1.2 12.9 9.5 2.4 0.0 12.2 11.8 26.2 24.7 25.0 1.4 1.3 6.7 4.2 9.5 10.5 111.0 51.3 3.3 6.1 33.7 21.3 8.8 16.8 26.3 19.6 905.0 34.0 27.7 0.0 27.2 21.8 7.4 2.9 12.4 2.0 2.3 0.2 205.9 24.8 6.6 6.6 50.0 21.3 8.1 5.9 4.0 6.3 232.9 4.1 18.4 5.0 1.9 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.4;Cone photoreceptor cells: 25.0;Horizontal cells: 20.2;Oligodendrocytes: 22.7;Rod photoreceptor cells: 33.7;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 58.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: AB_10599306, HPA030118: AB_10601238" "unprognostic (1.44e-3)" "unprognostic (3.40e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.61e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (2.97e-3)" "unprognostic (2.40e-2)" "prognostic unfavorable (3.09e-8)" "unprognostic (5.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-2)" 7.7 8.7 24.3 4.2 28.8 20.5 10.9 14.3 39.1 20.4 8.2 11.2 4.0 13.9 1.3 8.1 17.1 2.8 6.9 30.0 21.0 10.1 5.6 6.8 5.8 19.9 16.5 26.9 11.9 4.2 33.6 1.6 18.0 12.5 1.3 9.9 7.4 3.3 3.4 9.8 9.2 2.0 15.2 11.1 10.4 39.6 19.5 11.7 18.0 1.3 2.2 9.4 13.7 22.1 9.0 5.6 15.5 11.7 0.6 1.5 1.2 7.2 0.9 2.7 1.9 2.3 6.6 5.2 2.6 2.1 2.3 2.4 1.9 2.0 1.0 16.4 3.6 7.6 8.6 2.1 0.7 2.7 58.1 2.2 0.4 2.1 0.8 2.2 1.6 20.4 3.7 22.1 2.4 6.8 18.8 7.4 3.5 3.4 2.5 25.4 2.5 2.5 1.2 1.4 15.4 9.4 3.2 5.7 1.1 1.9 8.3 7.5 3.1 11.0 10.6 5.8 8.5 19.5 4.0 5.2 4.0 8.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 28.8 14.3 39.1 30.0 21.0 19.9 16.5 18.0 15.2 19.5 22.1 2.7 0.0 1.1 7.8 1.0 1.7 1.0 1.0 4.6 27.4 4.8 4.7 2.3 2.8 2.7 1.8 25.0 0.7 5.1 1.4 0.0 0.4 11.4 6.1 4.8 1.6 3.5 6.5 12.1 0.7 1.0 3.5 3.6 2.5 5.1 7.3 1.1 1.5 1.2 20.2 11.3 2.3 2.0 0.8 1.9 8.9 4.1 0.7 0.0 1.9 0.2 7.3 0.0 19.1 22.7 0.7 0.6 3.0 2.2 0.6 0.3 0.2 4.2 33.7 0.0 4.6 3.1 22.2 6.2 4.2 1.7 0.4 3.6 7.2 2.8 0.6 ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.1;lymphoid tissue: 120.9" "Cell type enhanced" "Detected in many" "B-cells: 65.3;dendritic cells: 70.0;Hofbauer cells: 86.6;Kupffer cells: 77.2;Macrophages: 76.0;NK-cells: 70.0;T-cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 103.0;HL-60: 76.7;Karpas-707: 90.8;MOLT-4: 93.0;RPMI-8226: 180.7;THP-1: 83.7;U-698: 90.4;U-937: 79.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA000301: , HPA001012: AB_1078201, HPA001083: AB_1078199" "unprognostic (3.54e-2)" "prognostic favorable (3.94e-5)" "prognostic unfavorable (1.97e-5)" "unprognostic (5.79e-2)" "unprognostic (9.42e-2)" "prognostic favorable (3.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.39e-1)" "unprognostic (3.27e-1)" "unprognostic (1.37e-1)" "unprognostic (7.81e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (8.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" 20.0 12.5 5.2 52.2 5.4 119.1 13.4 6.9 6.5 9.9 15.0 18.6 14.2 9.7 3.1 7.0 12.9 14.4 10.3 5.7 6.3 22.6 8.6 36.2 73.8 10.9 8.3 5.4 5.9 1.7 8.6 21.2 9.3 11.1 6.9 1.2 9.2 3.8 4.3 5.0 49.7 6.5 8.2 120.9 12.6 7.2 8.5 42.7 10.9 1.5 33.7 11.6 9.2 10.0 1.5 0.6 1.0 5.9 0.2 0.0 2.5 1.0 0.4 0.1 0.2 0.4 42.8 103.0 5.9 0.1 0.8 1.2 4.6 0.2 0.0 27.8 3.4 44.4 0.5 1.7 3.6 76.7 59.7 0.2 0.4 0.0 0.3 0.5 9.1 22.4 0.5 90.8 0.5 4.6 93.0 1.5 3.7 0.4 0.3 44.6 12.0 180.7 0.4 0.7 8.4 12.1 0.9 2.1 0.9 1.2 19.0 83.7 1.9 0.3 1.3 0.9 0.5 60.1 55.8 90.4 0.7 79.9 0.2 10.9 26.1 35.4 26.2 42.4 18.6 18.0 18.8 21.1 25.5 16.9 17.4 17.4 22.4 16.0 59.4 31.6 23.5 26.1 5.2 5.4 6.9 6.5 5.7 6.3 10.9 8.3 9.3 8.2 8.5 10.0 16.0 9.6 22.7 2.6 65.3 3.4 0.6 0.2 0.0 13.7 2.4 6.1 48.3 1.5 2.7 18.4 4.2 1.9 70.0 9.5 5.9 0.9 0.1 2.4 1.4 13.0 4.8 11.3 2.1 0.6 1.9 3.5 7.1 1.5 34.2 7.7 4.2 0.5 86.6 3.3 1.4 6.6 0.0 77.2 31.5 0.2 0.9 76.0 10.6 19.7 42.5 1.9 70.0 2.0 0.7 0.2 0.5 0.0 32.9 0.5 3.0 0.8 8.7 4.6 0.0 7.1 2.6 0.7 5.2 1.6 1.7 1.4 69.5 1.1 5.0 0.4 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGEF4 "ASEF, KIAA1112, STM6" ENSG00000136002 "Rho guanine nucleotide exchange factor 4" Q9NR80 2 130836914-131047263 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.3;skin 1: 39.8" "Cell type enhanced" "Detected in many" "Astrocytes: 333.3;Excitatory neurons: 83.0;Inhibitory neurons: 83.5;Oligodendrocyte precursor cells: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 12 "dendritic cells: 1.0;T-cells: 1.4" "Cell line enhanced" "Detected in many" "HaCaT: 39.9;hTCEpi: 78.9;REH: 20.3;SCLC-21H: 52.9" HPA018267 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA018267: AB_1845006" "unprognostic (2.30e-3)" "unprognostic (8.84e-2)" "unprognostic (5.32e-2)" "unprognostic (1.18e-2)" "unprognostic (4.44e-1)" "unprognostic (2.60e-2)" "unprognostic (4.69e-2)" "unprognostic (2.14e-2)" "unprognostic (8.97e-2)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.68e-2)" "prognostic favorable (7.00e-4)" "unprognostic (3.93e-3)" "unprognostic (9.71e-3)" 5.6 5.0 53.1 1.0 56.8 0.0 2.1 32.5 67.3 11.2 27.3 7.0 0.2 2.9 1.6 34.0 8.4 2.9 1.4 63.1 38.1 0.4 0.9 3.1 0.3 44.4 39.7 7.8 17.9 2.5 15.4 0.2 39.9 5.2 0.8 10.2 5.7 9.3 9.0 39.8 1.3 4.1 41.5 0.2 3.1 5.2 44.6 1.8 6.1 2.6 2.5 4.5 19.9 46.0 4.8 2.0 0.9 16.6 0.1 0.0 0.4 5.3 0.3 0.3 0.2 0.9 1.5 0.0 0.5 2.1 3.6 39.9 2.4 10.5 0.0 0.0 2.2 0.0 7.0 0.0 0.6 0.0 0.1 0.0 78.9 1.2 5.8 0.1 0.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 5.8 0.7 7.2 20.3 0.2 0.8 3.2 0.1 52.9 7.0 0.8 8.3 0.6 1.6 0.5 0.5 0.0 0.0 0.3 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.5 0.0 0.0 0.5 1.4 0.0 0.0 0.0 1.0 0.5 0.1 53.1 56.8 32.5 67.3 63.1 38.1 44.4 39.7 39.9 41.5 44.6 46.0 0.1 25.6 0.0 333.3 0.0 17.3 1.2 4.8 15.4 18.8 0.9 5.5 3.2 1.5 2.9 0.0 37.5 1.0 2.9 0.3 0.0 0.8 10.9 7.5 1.0 0.5 0.0 2.7 83.0 0.0 0.3 3.5 2.6 5.4 0.0 3.1 0.7 0.4 0.4 28.6 83.5 0.9 0.0 0.6 2.4 8.2 5.0 0.3 5.4 11.2 0.7 3.7 0.0 143.7 28.3 1.5 0.0 10.9 0.0 1.2 0.3 0.9 6.6 13.9 0.0 3.1 1.1 1.1 4.2 17.4 19.9 0.3 0.8 0.4 0.4 0.8 ARHGEF9 "KIAA0424, PEM-2" ENSG00000131089 "Cdc42 guanine nucleotide exchange factor 9" O43307 X 63634967-63809274 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 88.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 184.3;Cone photoreceptor cells: 233.5;Rod photoreceptor cells: 320.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035419, HPA055291" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA035419: AB_10669859, HPA055291: AB_2682774" "unprognostic (3.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.02e-2)" "unprognostic (2.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.14e-1)" "unprognostic (1.66e-1)" "unprognostic (1.98e-3)" "unprognostic (1.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.08e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.02e-5)" "unprognostic (4.56e-2)" "unprognostic (9.27e-2)" "unprognostic (3.15e-2)" "unprognostic (8.98e-2)" 7.7 15.6 32.6 6.4 39.3 4.1 10.6 5.1 51.0 8.4 5.2 13.6 15.8 9.3 7.1 11.2 7.7 8.0 35.9 46.2 36.6 13.2 5.6 6.3 6.3 13.1 14.3 16.2 5.2 15.0 15.7 5.8 14.3 13.8 14.3 88.1 6.3 14.6 5.9 9.1 13.4 17.2 10.0 6.9 8.9 2.8 26.7 9.5 8.2 8.9 7.3 14.3 6.5 27.2 6.3 9.7 20.2 10.3 7.6 11.1 1.2 12.3 11.8 12.8 9.8 0.6 6.8 14.1 8.7 8.0 10.8 0.2 8.4 14.5 15.1 18.5 6.6 13.7 4.5 0.6 4.5 6.7 4.2 12.2 6.9 5.9 18.5 11.9 7.1 14.8 1.5 20.8 14.0 10.0 12.6 3.3 16.4 6.2 12.1 22.9 48.2 13.5 7.8 6.0 0.1 5.1 5.6 9.8 6.7 8.4 7.5 8.9 3.4 7.1 6.4 34.6 5.1 7.8 6.5 10.2 8.7 10.7 5.1 0.8 1.4 1.3 4.5 2.0 3.2 2.2 2.7 3.1 2.2 2.9 3.3 2.9 1.1 8.4 1.4 1.8 2.6 1.9 32.6 39.3 5.1 51.0 46.2 36.6 13.1 14.3 14.3 10.0 26.7 27.2 9.2 9.6 11.4 59.4 20.3 5.7 6.5 8.7 12.5 184.3 26.0 17.4 45.9 7.2 10.0 11.0 233.5 5.0 19.4 18.2 13.7 6.3 2.0 6.5 9.8 10.8 20.9 3.8 105.9 8.8 1.4 11.8 24.5 6.0 14.5 20.0 11.7 10.7 10.5 82.4 90.5 16.0 12.2 5.7 6.3 6.2 15.5 8.2 14.2 33.7 3.8 29.9 34.0 89.0 50.5 7.9 14.5 15.4 12.4 4.3 19.1 17.3 9.3 320.8 0.0 12.7 22.0 1.9 3.4 11.2 6.0 4.4 21.8 39.6 21.8 6.1 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARL13B "ARL2L1, DKFZp761H079, JBTS8" ENSG00000169379 "ADP ribosylation factor like GTPase 13B" Q3SXY8 3 93980139-94055678 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 18.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Rod photoreceptor cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048926 Approved Uncertain Microtubules,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules Cytosol "HPA048926: AB_2680559" "unprognostic (2.29e-2)" "unprognostic (2.35e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (5.42e-3)" "unprognostic (8.86e-2)" "unprognostic (2.73e-1)" "unprognostic (5.41e-2)" "unprognostic (7.50e-2)" 3.4 2.5 1.3 2.9 1.6 0.8 2.3 1.2 2.5 4.1 8.7 1.9 0.8 4.6 1.0 3.3 4.1 4.0 2.0 1.2 1.1 3.6 2.6 4.1 2.1 1.5 1.8 3.2 1.5 3.6 2.0 2.7 1.6 2.0 1.4 18.2 1.5 2.6 0.7 1.4 1.9 4.2 1.5 2.9 1.6 3.5 1.2 2.5 4.3 1.7 1.7 3.1 1.7 2.0 8.3 12.5 7.9 4.3 13.3 3.5 3.6 7.8 4.8 11.8 15.9 8.0 4.4 5.9 11.3 6.9 7.1 5.1 7.2 5.3 16.2 10.5 6.4 12.7 5.6 5.4 6.0 15.2 6.9 5.2 2.1 12.3 19.0 4.5 4.0 8.7 12.5 7.3 6.7 3.1 12.3 1.2 2.9 4.3 7.5 7.2 25.8 2.0 5.7 1.2 18.0 4.6 15.9 0.9 9.4 2.9 2.1 3.5 7.7 11.6 11.0 6.8 9.6 1.8 2.0 11.7 8.5 8.8 8.5 6.4 3.4 2.9 3.7 4.2 3.8 3.9 3.3 3.0 3.0 3.4 3.3 3.1 2.0 4.3 4.8 4.8 2.9 1.8 1.3 1.6 1.2 2.5 1.2 1.1 1.5 1.8 1.6 1.5 1.2 2.0 27.2 93.0 39.6 31.6 11.3 46.8 28.1 8.6 10.2 19.0 11.0 16.8 8.1 12.8 19.7 1.8 41.7 1.9 7.1 1.3 15.6 17.1 14.8 30.1 25.2 31.7 22.1 6.5 58.4 11.8 6.3 48.5 10.2 11.2 45.6 9.2 17.5 7.7 12.1 15.2 41.5 3.1 12.2 7.0 21.6 6.4 23.9 10.7 16.0 38.4 6.0 26.9 6.2 29.7 49.8 11.4 3.8 25.6 8.0 13.9 1.8 18.7 71.9 102.0 6.6 59.4 33.8 43.1 14.5 12.7 58.7 0.8 13.2 16.5 3.1 10.6 ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 154.8" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 164.1;NTERA-2: 117.2;SuSa: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" 17.0 46.2 28.7 11.5 29.1 0.5 17.6 22.8 29.7 36.9 26.5 25.4 5.4 30.6 154.8 9.2 28.8 20.6 33.2 29.1 31.6 28.3 3.2 16.8 8.5 25.9 26.2 47.8 18.9 71.2 78.3 26.3 27.5 28.3 7.9 15.3 44.5 67.9 6.2 6.5 13.0 32.3 23.4 21.3 16.3 5.8 28.1 7.7 59.7 7.5 6.5 26.9 20.1 25.4 0.0 0.0 50.8 0.4 43.6 39.4 0.4 56.0 70.4 1.4 1.4 0.0 21.8 0.0 0.0 74.6 0.0 1.5 0.0 1.3 0.6 0.0 2.0 0.2 60.9 0.0 46.4 0.4 0.1 63.7 17.6 43.5 0.4 68.3 59.7 0.0 0.2 0.3 164.1 0.0 0.0 0.6 117.2 3.4 0.3 14.5 88.9 0.3 2.8 0.0 20.4 36.6 0.0 0.2 1.7 90.3 25.9 0.1 13.0 61.9 65.1 38.8 0.4 0.0 0.0 0.2 55.7 0.1 1.2 0.0 0.4 0.0 1.0 0.9 0.4 2.8 0.9 0.9 0.7 4.0 2.4 2.5 0.0 2.8 0.6 0.9 0.7 1.1 28.7 29.1 22.8 29.7 29.1 31.6 25.9 26.2 27.5 23.4 28.1 25.4 10.4 16.0 6.4 8.5 8.2 4.2 16.4 5.8 21.1 12.5 18.0 20.8 28.7 5.7 11.4 33.1 8.4 1.2 2.4 0.1 3.9 9.6 0.2 11.2 23.4 13.3 9.1 3.2 15.4 2.0 0.7 28.4 4.6 15.2 2.5 18.1 19.2 0.7 3.8 1.7 14.3 3.0 2.0 2.4 6.5 1.3 24.2 7.4 5.4 11.2 7.1 9.3 0.0 16.1 14.0 2.2 0.1 24.5 2.8 16.5 0.3 4.3 4.9 11.3 59.2 31.8 23.9 1.4 1.9 3.8 3.0 5.1 2.5 4.6 1.6 7.2 ARNTL2 "bHLHe6, BMAL2, CLIF, MOP9, PASD9" ENSG00000029153 "Aryl hydrocarbon receptor nuclear translocator like 2" Q8WYA1 12 27332854-27425289 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.1;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 45.6;Excitatory neurons: 78.8;Pancreatic endocrine cells: 86.9;Prostatic glandular cells: 109.0;Urothelial cells: 128.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 6.4" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 121.9;U-2197: 159.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059074 Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nucleoli" "HPA059074: AB_2683897" "unprognostic (6.86e-2)" "unprognostic (6.16e-2)" "unprognostic (5.88e-3)" "unprognostic (1.01e-2)" "unprognostic (3.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.84e-3)" "unprognostic (2.97e-3)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (5.29e-6)" "unprognostic (5.26e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (7.81e-3)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" 3.0 1.0 1.3 10.0 6.4 2.3 2.1 0.0 3.6 5.8 0.0 2.5 2.8 1.2 0.2 28.1 0.9 3.6 0.8 2.8 1.6 1.1 4.7 2.3 5.2 0.0 0.5 0.2 1.3 1.5 0.8 2.8 0.0 1.1 3.2 0.4 7.2 0.6 0.2 7.6 2.6 4.6 0.0 1.0 10.9 2.7 0.6 4.4 0.6 0.8 22.2 14.7 11.9 2.2 76.0 19.2 4.2 1.6 3.6 11.0 58.3 26.3 34.5 16.8 26.2 18.2 57.4 0.6 14.4 12.6 51.9 30.6 12.3 92.1 42.7 121.9 15.7 14.6 11.7 15.2 4.8 29.6 6.1 4.0 8.1 58.8 45.6 28.9 80.0 17.7 7.5 29.8 19.6 9.2 16.2 16.2 32.1 25.7 65.8 29.8 68.2 4.7 14.1 42.8 13.6 2.2 13.5 2.1 0.4 10.0 2.9 9.7 54.6 54.2 31.4 159.5 110.0 4.4 8.4 0.1 46.5 23.5 10.9 1.3 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 1.3 6.4 0.0 3.6 2.8 1.6 0.0 0.5 0.0 0.0 0.6 2.2 2.1 3.2 1.3 1.3 0.4 0.8 45.6 8.6 1.2 0.9 1.6 0.8 0.9 11.5 7.5 9.2 0.0 1.9 0.3 1.5 0.0 22.1 3.8 7.9 0.7 6.9 1.2 3.4 78.8 27.4 4.0 3.2 28.1 11.8 0.0 5.3 2.5 3.5 1.4 0.0 24.8 3.3 2.0 2.5 5.4 4.4 0.0 2.9 1.8 7.5 15.7 0.0 0.0 8.5 2.3 86.9 1.4 0.0 3.4 109.0 1.7 0.6 2.7 0.1 0.0 1.7 3.6 3.1 4.7 6.6 2.3 4.2 1.3 0.2 2.1 128.2 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASB10 GLC1F ENSG00000146926 "Ankyrin repeat and SOCS box containing 10" Q8WXI3 7 151175698-151187832 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 26.7;skeletal muscle: 77.9;tongue: 14.2" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079685 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA079685: " "unprognostic (6.72e-3)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 77.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236194872-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;heart muscle: 7.4;skeletal muscle: 11.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 6.5;Excitatory neurons: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" "unprognostic (1.12e-1)" "unprognostic (7.33e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-6)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 4.8 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.0 0.6 0.0 0.0 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 1.5 0.0 0.0 0.5 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.8 1.0 1.0 1.0 0.6 2.3 2.0 1.4 1.5 3.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 ATP1B4 ENSG00000101892 "ATPase Na+/K+ transporting family member beta 4" Q9UN42 X 120362085-120383249 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "skeletal muscle: 55.7;tongue: 21.6" "Group enriched" "Detected in some" 32 "Cardiomyocytes: 1.7;Skeletal myocytes: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.59e-2)" "unprognostic (6.02e-4)" "unprognostic (5.78e-1)" "unprognostic (5.29e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.3 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 55.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.7;lymphoid tissue: 30.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 105.4;Breast myoepithelial cells: 73.9;granulocytes: 243.7;NK-cells: 103.0;T-cells: 116.5;Urothelial cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.3" "Cell line enhanced" "Detected in many" "HDLM-2: 368.9;MCF7: 134.7;RT4: 83.3;SK-BR-3: 64.8;U-937: 101.6" "Not detected" "Not detected" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA059588: AB_2684074, HPA064962: AB_2685392" "unprognostic (3.33e-3)" "unprognostic (4.87e-3)" "prognostic unfavorable (8.30e-4)" "prognostic favorable (5.35e-6)" "unprognostic (3.02e-2)" "prognostic favorable (7.91e-5)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (6.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (3.74e-9)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "prognostic favorable (4.30e-4)" 5.5 1.3 1.0 20.5 1.8 21.7 7.8 1.0 1.4 2.2 1.1 3.0 2.6 1.3 1.1 2.9 1.9 5.8 2.4 1.0 1.2 1.4 2.9 8.0 30.6 1.5 1.4 0.5 0.9 8.0 0.5 4.1 1.7 5.5 1.4 0.0 6.5 1.8 0.4 2.9 9.7 2.3 1.2 26.9 7.8 0.6 2.2 7.2 1.9 1.0 20.4 18.2 2.9 1.5 4.7 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 368.9 0.0 7.5 0.0 1.6 11.5 10.0 36.3 0.1 0.0 0.0 0.0 0.0 0.0 8.1 2.0 10.3 0.0 134.7 4.7 30.8 0.2 54.9 0.0 1.1 0.0 6.3 0.0 83.3 0.1 0.0 0.0 64.8 2.7 0.0 6.1 18.7 0.0 0.0 0.0 4.4 0.3 32.8 36.9 0.3 0.0 101.6 0.1 3.6 25.5 8.2 55.0 13.7 43.4 21.3 59.7 74.2 25.2 17.5 23.1 50.4 14.4 21.3 13.2 2.9 130.3 27.8 1.0 1.8 1.0 1.4 1.0 1.2 1.5 1.4 1.7 1.2 2.2 1.5 2.9 9.6 29.3 0.0 17.1 5.4 50.8 5.7 0.6 0.0 105.4 73.9 0.3 1.5 13.5 3.7 0.0 0.4 36.9 0.0 0.0 0.8 0.5 0.9 0.6 5.0 0.0 7.2 0.2 2.5 0.4 4.4 10.2 1.9 243.7 0.0 2.5 0.7 61.3 0.0 0.1 0.0 34.6 15.4 10.7 0.6 0.0 21.7 5.4 1.0 16.7 0.0 103.0 0.0 0.1 11.0 0.1 0.0 29.9 22.1 0.0 0.2 12.8 0.0 0.0 1.0 2.0 0.0 0.1 0.4 3.4 1.1 116.5 0.2 0.5 74.3 BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810024-24949101 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 58.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 203.2;Early spermatids: 161.4;Exocrine glandular cells: 139.9;Langerhans cells: 265.8;Late spermatids: 370.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 19.0;glioma: 10.7;lung cancer: 7.2;ovarian cancer: 24.0;testis cancer: 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 17.1" "Group enriched" "Detected in many" 10 "dendritic cells: 5.8;monocytes: 17.1" "Cell line enhanced" "Detected in many" "HDLM-2: 261.3;NTERA-2: 287.4;RH-30: 310.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain NA NA 97000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "HPA048592: AB_2680454" "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.38e-4)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavorable (8.54e-4)" 6.7 5.9 4.1 7.1 5.7 2.4 2.1 11.1 10.6 3.6 0.0 3.0 0.8 8.6 1.0 2.0 7.2 4.4 1.8 3.0 19.6 1.2 1.3 9.6 6.4 19.4 19.8 7.2 58.2 0.4 6.6 15.2 22.7 0.9 2.6 14.5 1.7 0.8 0.7 0.6 3.6 5.7 6.4 2.0 1.8 7.1 14.0 5.2 1.2 2.0 5.3 4.1 1.3 7.9 30.3 12.1 106.8 0.2 30.5 59.0 54.9 60.9 40.6 33.4 55.2 67.1 83.1 114.0 0.3 100.7 6.5 12.0 77.2 0.5 88.2 261.3 15.4 91.1 2.0 37.3 112.3 105.9 31.6 77.4 2.0 85.1 17.8 73.0 114.3 56.9 88.5 1.1 28.7 0.6 65.2 30.1 287.4 0.0 8.1 0.1 310.3 1.4 0.1 10.4 0.1 60.1 0.1 0.2 0.5 114.8 0.2 45.2 150.8 19.7 72.9 80.4 58.1 13.2 13.9 152.7 69.9 62.4 0.3 0.0 2.3 0.0 0.0 3.6 0.1 1.1 0.0 0.1 5.8 0.0 0.0 0.0 1.0 0.1 17.1 3.4 0.2 1.0 4.1 5.7 11.1 10.6 3.0 19.6 19.4 19.8 22.7 6.4 14.0 7.9 1.7 16.0 26.0 1.6 1.3 8.7 0.1 2.5 0.0 203.2 0.3 0.3 1.6 1.5 2.2 0.0 2.1 61.2 4.3 0.0 1.9 1.8 161.4 41.5 92.6 16.8 0.0 20.8 39.6 139.9 23.2 27.6 0.0 89.1 11.4 117.4 7.9 0.3 72.3 42.1 81.8 0.0 14.2 87.1 265.8 370.3 7.2 59.9 7.2 38.4 22.3 7.1 0.0 84.4 57.4 49.6 0.0 4.1 0.7 0.2 0.0 0.1 3.3 12.2 6.6 14.9 17.4 1.9 1.6 0.5 7.2 22.4 2.8 41.3 0.1 0.1 BEX3 "Bex, DXS6984E, HGR74, NADE, NGFRAP1" ENSG00000166681 "Brain expressed X-linked 3" Q00994 X 103376395-103378164 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1607.8;Distal tubular cells: 1453.7;Granulosa cells: 700.3;Proximal tubular cells: 688.0;Syncytiotrophoblasts: 804.2;Theca cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 150.9;T-reg: 137.1" "Lineage enriched" "Detected in all" 5 "T-cells: 150.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018886 Approved Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018886: AB_1854453" "unprognostic (7.74e-2)" "unprognostic (6.56e-2)" "unprognostic (8.15e-3)" "prognostic unfavorable (7.23e-5)" "unprognostic (2.70e-1)" "unprognostic (1.93e-3)" "unprognostic (7.15e-2)" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.10e-2)" "unprognostic (3.85e-3)" "unprognostic (2.00e-1)" "prognostic favorable (1.28e-4)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.38e-1)" "unprognostic (3.32e-2)" "unprognostic (8.68e-2)" 106.8 345.8 382.4 39.6 395.3 31.1 111.0 353.0 432.9 144.6 462.7 123.4 31.2 149.1 499.4 72.8 150.9 77.1 244.7 401.5 491.6 263.6 92.8 116.8 29.3 368.8 392.1 463.7 120.0 231.1 373.7 207.0 384.1 166.7 53.0 135.9 99.5 224.9 19.8 61.6 56.3 116.5 364.9 97.3 94.6 139.9 419.3 97.0 274.6 44.5 28.4 107.8 104.6 365.7 218.5 305.3 561.5 222.3 508.5 567.3 256.6 244.7 409.8 299.5 475.0 317.9 238.1 0.3 427.8 288.7 222.0 85.3 394.1 302.5 299.4 0.8 280.6 98.7 502.9 87.4 396.2 0.8 37.4 613.4 252.2 397.3 348.0 533.6 469.5 225.0 0.1 1.0 542.2 486.1 227.2 2.7 750.5 0.1 232.3 0.4 350.3 0.5 317.9 365.3 377.3 391.4 264.7 3.2 380.3 359.8 142.4 31.8 291.5 191.6 123.3 374.6 110.0 2.2 1.0 1.6 395.3 0.3 189.1 0.3 3.7 1.1 4.1 0.9 2.2 4.6 71.8 19.1 6.4 1.2 150.9 70.8 13.9 28.9 0.8 14.5 137.1 66.5 382.4 395.3 353.0 432.9 401.5 491.6 368.8 392.1 384.1 364.9 419.3 365.7 118.5 326.9 227.7 0.0 12.6 0.0 0.0 0.0 0.0 0.0 217.4 433.2 0.0 0.0 104.0 518.6 0.0 1607.8 4.7 0.0 1453.7 201.3 0.0 187.0 284.8 132.3 0.0 0.0 0.0 70.9 471.7 189.2 0.0 144.1 16.4 700.3 0.0 0.0 172.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 1.7 0.0 0.0 688.0 23.3 0.0 0.0 0.0 117.8 0.0 0.0 0.0 0.0 804.2 12.8 696.8 0.0 0.0 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 71.3" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 17.7;Fibroblasts: 28.9;Microglial cells: 26.2;Smooth muscle cells: 26.3" "Cancer enhanced" "Detected in many" "lung cancer: 2.8" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.3;pons: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 27.6;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" 1.5 1.0 0.1 1.0 0.3 0.2 1.0 0.6 0.5 0.0 2.0 6.2 8.3 0.0 0.0 0.9 0.0 2.3 3.8 0.1 0.0 2.4 3.2 12.9 0.4 2.3 0.3 0.0 1.6 1.1 3.5 71.3 2.9 14.1 7.4 0.0 1.2 0.0 4.4 0.1 9.7 0.3 0.1 0.0 3.3 0.0 0.1 0.2 1.0 12.3 0.2 9.3 0.3 0.0 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.5 0.1 0.0 2.3 0.3 2.9 0.1 0.1 0.0 1.8 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.0 17.7 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 2.7 0.4 0.0 0.8 28.9 0.0 0.0 0.0 0.0 2.2 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 26.2 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.6 26.3 0.0 0.1 0.3 0.0 1.9 0.6 0.0 0.0 0.1 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248490-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031355: AB_10611812" "prognostic favorable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (2.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.23e-2)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-1)" "prognostic favorable (2.25e-4)" "unprognostic (8.48e-3)" "prognostic favorable (6.51e-5)" "unprognostic (6.55e-2)" "unprognostic (3.22e-1)" "unprognostic (6.86e-2)" "unprognostic (9.85e-2)" 69.4 26.3 52.1 20.4 52.6 28.2 56.6 48.3 60.3 32.6 48.1 43.8 28.8 31.4 28.1 50.9 30.8 20.5 52.1 54.2 51.7 34.5 44.2 34.7 22.0 49.7 51.0 36.7 13.2 12.6 39.9 15.6 49.9 43.6 23.1 14.6 42.8 23.5 169.4 48.5 39.5 18.8 48.4 31.4 46.9 79.3 52.1 18.4 30.4 144.6 19.0 38.9 37.7 51.3 50.8 39.8 21.4 56.8 66.8 46.2 0.1 45.6 41.1 69.2 46.9 31.3 45.2 15.9 27.4 67.0 14.5 66.2 41.3 43.9 34.0 41.2 33.5 11.7 58.6 0.0 45.6 35.8 21.7 48.3 59.6 31.9 25.7 26.9 55.9 52.2 0.0 0.3 37.3 71.8 37.8 14.5 9.1 47.6 67.6 40.3 0.1 14.9 26.5 55.0 34.8 14.8 42.9 34.3 35.0 14.7 69.9 45.3 37.9 55.5 1.5 82.1 57.8 10.2 14.7 7.8 57.2 16.4 44.1 0.5 0.6 2.9 2.3 1.0 2.2 1.3 2.4 2.3 0.7 0.7 1.8 1.2 0.3 0.4 0.8 1.5 5.3 0.6 52.1 52.6 48.3 60.3 54.2 51.7 49.7 51.0 49.9 48.4 52.1 51.3 31.5 25.6 24.3 3.9 5.4 11.7 25.7 6.5 6.2 23.1 24.0 23.4 22.0 14.3 15.3 11.0 6.2 2.8 25.3 31.0 21.5 5.7 15.0 25.6 19.5 17.8 20.4 5.2 12.4 0.0 3.8 17.3 10.2 34.9 24.7 22.2 17.9 15.4 7.8 20.2 12.5 31.2 10.2 9.8 10.0 35.2 9.3 10.3 12.4 8.4 3.6 19.1 5.2 5.0 3.7 1.0 11.6 7.5 7.6 16.3 20.5 11.6 15.5 18.8 13.1 15.7 13.0 7.8 8.3 9.6 12.6 2.2 16.4 15.2 21.9 19.5 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 BTG3 "ANA, ANA/BTG3, APRO4, tob55" ENSG00000154640 "BTG anti-proliferation factor 3" Q14201 21 17593653-17612945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 526.3;Syncytiotrophoblasts: 1692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 31.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018400 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA018400: AB_1845487" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (6.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.34e-1)" "unprognostic (2.98e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (1.43e-2)" "unprognostic (2.67e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.42e-2)" "unprognostic (3.08e-1)" "unprognostic (9.92e-2)" "unprognostic (2.40e-1)" 30.8 27.9 13.1 14.0 14.6 55.9 24.2 13.3 16.1 32.0 14.0 28.8 16.5 48.2 110.3 25.4 51.5 22.8 28.8 14.4 16.2 23.5 12.9 44.7 13.9 14.8 13.4 28.4 21.0 35.3 43.7 61.1 15.0 25.2 26.9 5.1 27.2 20.5 4.9 42.5 16.4 28.4 14.7 15.1 21.2 47.5 15.5 27.4 27.2 5.3 16.4 39.3 37.7 17.8 70.5 14.4 84.9 6.8 28.4 50.9 62.6 96.0 109.8 83.5 84.9 33.0 29.3 31.5 44.7 34.8 108.7 17.1 42.5 63.3 91.9 99.6 60.6 23.5 30.9 31.5 59.4 26.6 44.3 44.4 88.2 70.8 67.7 47.7 42.0 30.7 22.9 113.6 78.3 0.0 51.2 4.0 44.4 9.7 4.2 16.6 110.5 23.1 55.2 31.3 43.2 34.9 71.9 36.6 86.7 96.0 1.2 28.6 27.7 84.0 89.1 65.6 96.9 74.1 64.6 29.5 84.4 0.2 102.2 1.0 2.3 4.0 8.1 1.7 9.4 7.4 13.6 13.0 1.9 6.3 6.6 9.1 0.2 6.2 1.9 8.8 31.7 5.5 13.1 14.6 13.3 16.1 14.4 16.2 14.8 13.4 15.0 14.7 15.5 17.8 65.2 205.1 156.5 0.7 44.7 360.1 526.3 309.9 178.7 1.1 64.8 55.0 9.3 34.3 195.5 58.8 0.0 436.5 61.6 25.3 39.2 56.9 8.6 197.0 97.1 51.0 108.3 99.1 2.2 39.3 88.6 132.5 17.9 147.3 65.4 13.5 32.2 5.5 55.6 23.5 3.1 47.9 69.2 16.5 140.4 24.8 70.2 54.5 85.4 16.9 33.5 19.5 12.3 20.1 14.6 52.9 22.7 46.6 75.1 463.0 2.6 2.1 104.3 1.0 92.1 95.5 99.1 300.0 267.2 92.7 294.4 1692.7 99.2 47.5 48.6 470.3 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C10orf71 FLJ45913 ENSG00000177354 "Chromosome 10 open reading frame 71" Q711Q0 10 49299170-49327492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 280.2;tongue: 81.9" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 56.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "K-562: 6.9;RH-30: 9.9" "Not detected" "Not detected" HPA057556 Approved Nucleoplasm,Mitochondria NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Mitochondria "HPA057556: AB_2683467" "unprognostic (1.25e-2)" "unprognostic (3.97e-2)" "unprognostic (4.16e-2)" "unprognostic (5.58e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 44.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.3 21.9 0.0 0.0 0.1 1.3 0.0 0.0 1.2 0.0 280.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982037 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 9 "Enteroendocrine cells: 20.4" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cell line enriched" "Detected in single" 4 "THP-1: 2.6" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" 0.2 0.6 0.3 0.1 0.3 0.1 0.1 1.2 0.7 0.1 0.2 0.3 0.7 0.0 0.1 0.6 0.0 0.3 0.6 0.2 0.3 0.0 0.2 0.4 0.6 0.2 0.5 0.0 4.4 0.1 0.2 0.2 0.3 0.1 0.6 0.0 0.2 0.0 16.5 0.0 0.3 0.0 0.2 0.6 1.9 0.5 0.7 0.1 0.2 3.7 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.2 0.7 0.2 0.3 0.2 0.5 0.3 0.2 0.7 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.8 0.0 0.8 0.6 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 39.9" "Cell type enriched" "Detected in some" 21 "Theca cells: 41.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;HSkMC: 2.0;hTEC/SVTERT24-B: 2.0;SCLC-21H: 2.3;THP-1: 2.0;U-2197: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.64e-1)" "unprognostic (1.14e-1)" "unprognostic (8.77e-3)" "unprognostic (7.13e-6)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-1)" "unprognostic (4.81e-2)" "unprognostic (3.15e-2)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (2.10e-1)" "unprognostic (5.13e-10)" "unprognostic (1.95e-1)" "unprognostic (6.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" 0.6 0.7 1.5 0.0 2.2 0.0 0.3 2.3 1.2 0.1 0.8 0.1 0.1 0.2 0.1 0.2 0.1 0.4 1.2 0.5 2.2 0.1 0.1 0.3 0.2 5.5 2.6 0.7 0.0 0.0 0.7 0.1 4.5 0.3 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.2 4.3 0.1 0.0 39.9 2.3 0.0 0.1 0.0 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.2 0.1 0.0 2.0 0.0 0.0 0.5 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 2.2 2.3 1.2 0.5 2.2 5.5 2.6 4.5 4.3 2.3 6.6 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 C2orf92 LINC01125 ENSG00000228486 "Chromosome 2 open reading frame 92" A0A1B0GVN3 2 97664217-97703064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 11.7" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Alveolar cells type 2: 7.5;Breast glandular cells: 3.3;Breast myoepithelial cells: 2.7;Club cells: 2.5;Endometrial ciliated cells: 3.7;Endometrial stromal cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HDLM-2: 2.0" "Not detected" "Not detected" NA NA "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.53e-2)" "unprognostic (8.76e-2)" "unprognostic (1.65e-2)" "unprognostic (2.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.09e-3)" "unprognostic (9.29e-2)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.98e-3)" "unprognostic (2.76e-2)" "unprognostic (7.45e-7)" "unprognostic (5.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (5.23e-5)" 1.4 1.3 2.5 0.3 2.6 0.3 1.8 2.7 4.4 1.8 2.6 1.1 0.4 0.9 1.7 0.8 1.2 0.2 1.6 2.5 2.5 1.5 2.6 1.6 0.2 2.6 2.6 0.9 2.0 0.3 1.5 0.3 2.7 2.0 0.4 0.7 1.9 0.6 1.5 2.0 1.3 0.2 2.6 3.0 1.1 11.7 2.6 0.4 3.5 0.0 0.5 0.8 1.3 2.8 0.1 0.0 1.6 0.3 0.7 0.6 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.8 0.2 0.0 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.4 0.1 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.8 0.4 0.6 0.1 0.5 0.7 0.2 1.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.7 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.6 2.7 4.4 2.5 2.5 2.6 2.6 2.7 2.6 2.6 2.8 2.5 0.0 7.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 3.3 2.7 0.0 0.0 2.5 0.0 0.0 0.7 1.6 0.0 0.0 0.6 0.0 3.7 2.7 0.5 0.0 0.0 0.0 1.6 0.6 0.6 0.0 2.3 1.3 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.9 1.6 0.0 0.0 C4orf3 "ALN, HCVFTP1" ENSG00000164096 "Chromosome 4 open reading frame 3" Q8WVX3 4 119296419-119304445 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026907 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA026907: AB_10600760" "unprognostic (2.97e-1)" "unprognostic (4.68e-2)" "unprognostic (3.32e-1)" "unprognostic (6.85e-3)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (2.04e-1)" "unprognostic (8.85e-2)" "unprognostic (4.90e-2)" "unprognostic (7.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.84e-1)" "prognostic favorable (3.46e-4)" "unprognostic (8.32e-2)" "unprognostic (2.65e-1)" "unprognostic (3.90e-1)" "unprognostic (1.59e-1)" 80.0 67.8 96.4 54.1 107.1 34.1 69.4 103.1 148.1 123.2 83.3 80.2 60.5 79.7 77.9 268.2 68.9 65.1 107.8 90.1 99.6 97.9 110.8 70.3 61.3 107.9 104.9 85.5 51.5 55.5 56.6 60.3 106.4 71.8 43.6 74.7 89.6 69.8 79.6 89.3 67.3 70.6 109.6 63.1 49.6 39.8 109.2 64.8 71.4 59.7 56.8 75.9 150.2 112.8 116.8 13.7 58.4 49.8 107.1 97.0 34.1 59.3 31.6 35.3 62.6 15.6 44.5 95.9 36.6 87.3 31.0 24.8 29.6 54.1 61.8 57.1 21.3 40.9 33.5 67.9 35.9 64.7 42.8 96.4 64.5 30.0 14.4 120.6 52.8 29.1 33.8 50.4 137.6 41.8 50.9 64.0 24.2 60.7 20.9 32.9 62.6 27.3 53.5 32.2 38.4 54.8 46.4 58.5 43.2 56.9 32.6 37.5 55.7 80.3 34.6 52.5 21.4 51.3 59.8 37.2 156.7 36.7 40.9 257.8 110.0 145.4 85.1 132.6 92.9 126.7 109.6 101.5 95.1 104.8 120.4 114.4 239.4 109.6 128.0 131.6 112.9 157.1 96.4 107.1 103.1 148.1 90.1 99.6 107.9 104.9 106.4 109.6 109.2 112.8 213.2 157.0 150.5 11.4 211.3 315.5 292.0 809.1 132.1 79.1 198.4 191.9 544.4 158.7 456.3 222.5 25.0 321.5 228.9 117.0 383.5 288.5 38.1 272.5 148.7 245.6 68.4 78.6 22.2 179.1 403.9 215.0 46.4 134.3 186.1 108.0 234.9 446.4 317.4 153.1 21.6 170.2 408.9 303.5 298.4 31.0 167.4 244.9 199.3 16.9 423.9 233.4 253.3 6.6 16.3 207.6 196.8 215.5 239.0 392.5 500.1 1070.2 542.7 78.9 197.2 145.8 246.0 182.7 67.0 245.9 346.6 445.7 203.2 150.3 135.8 428.1 C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement component 5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in many" "Early spermatids: 14.4;Hepatic stellate cells: 23.9;Kupffer cells: 48.6;Macrophages: 34.5" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.0" "Group enriched" "Detected in some" 4 "MCF7: 20.7;T-47d: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" 4.2 1.2 1.1 4.1 0.8 5.8 2.2 1.2 2.9 1.2 1.8 1.3 0.4 0.7 0.4 0.6 2.3 0.7 2.1 2.4 0.5 1.2 1.9 6.5 0.9 1.3 0.7 0.6 0.8 0.1 0.9 2.2 0.7 0.4 0.4 0.4 1.2 0.3 0.3 1.4 1.5 1.0 0.5 14.1 1.1 3.1 0.8 0.3 0.9 0.4 3.2 1.2 1.3 1.3 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.7 0.4 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 5.2 0.1 0.0 0.8 1.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.4 0.0 20.7 0.1 2.4 0.2 0.0 0.1 0.3 0.1 2.7 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 24.8 0.3 0.2 0.8 0.2 0.5 0.1 0.3 0.3 0.9 0.8 1.4 0.1 17.8 2.7 11.9 0.3 2.3 0.4 0.3 0.2 0.2 0.6 0.4 0.2 0.2 33.0 0.3 4.4 0.3 0.6 0.7 1.1 0.8 1.2 2.9 2.4 0.5 1.3 0.7 0.7 0.5 0.8 1.3 0.6 3.2 1.9 0.3 1.1 0.4 2.8 0.1 0.0 1.3 4.7 2.8 1.6 2.8 2.6 1.8 2.1 0.1 1.7 0.0 0.0 0.0 14.4 0.5 0.5 1.7 0.0 3.2 0.6 0.0 0.2 2.1 0.0 1.1 1.3 6.1 23.9 1.2 8.3 0.0 0.1 0.0 0.0 48.6 4.6 3.0 0.0 34.5 0.0 1.0 8.3 0.3 1.0 0.0 0.1 0.0 0.0 0.4 1.3 2.0 0.0 0.3 0.8 4.2 0.0 4.0 1.0 0.2 0.4 0.1 0.9 0.1 1.3 4.1 0.0 1.9 CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 5273.7" "Group enriched" "Detected in many" 8 "Erythroid cells: 221.3;Skeletal myocytes: 304.0" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEL: 47.3;RH-30: 78.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 53000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favorable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" 43.4 3.8 2.4 0.3 2.3 9.9 6.4 2.7 3.7 5.1 1.4 1.7 1.8 8.3 2.1 64.8 9.8 2.2 19.5 2.3 2.8 3.7 2.4 24.6 0.4 2.9 2.3 1.4 1.3 1.0 3.8 0.3 2.0 89.5 1.1 5.5 15.4 2.7 5273.7 5.2 4.4 19.1 2.5 0.8 4.1 2.9 2.5 1.4 3.0 1018.8 0.6 1.5 5.5 2.8 2.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.1 0.0 0.1 0.2 0.3 0.3 0.0 0.5 0.2 47.3 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 78.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 2.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.4 2.3 2.7 3.7 2.3 2.8 2.9 2.3 2.0 2.5 2.5 2.8 0.3 3.2 4.2 2.3 0.1 0.5 1.7 0.6 1.2 0.0 14.5 0.6 1.0 5.7 0.6 0.0 6.2 1.1 0.4 0.4 0.0 0.6 24.1 0.4 0.2 2.2 0.0 221.3 2.2 0.2 0.2 9.1 0.0 0.7 0.0 0.2 2.5 0.3 0.4 0.0 2.5 0.4 0.0 0.3 0.4 7.0 0.3 2.5 0.0 0.0 0.0 29.6 0.0 1.5 0.7 0.2 1.7 0.0 0.0 0.5 8.5 0.6 1.0 1.6 0.0 304.0 5.1 0.6 1.3 0.2 1.0 1.6 1.4 0.3 0.9 0.3 CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 99.3" "Group enriched" "Detected in many" 8 "Bipolar cells: 101.4;Enteroendocrine cells: 214.1;Excitatory neurons: 318.3;Horizontal cells: 249.0;Inhibitory neurons: 372.1;Oligodendrocyte precursor cells: 271.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in all" 4 "cerebellum: 99.3;cerebral cortex: 30.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 45.1;U-87 MG: 23.9" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" 1.0 2.3 15.4 0.3 15.8 0.1 0.9 99.3 30.4 0.6 0.0 0.7 1.2 0.8 1.1 0.2 3.2 0.1 0.6 15.1 6.8 0.5 0.2 0.2 0.4 7.2 11.2 0.9 2.6 0.1 4.2 0.0 10.6 0.4 0.4 7.1 0.2 0.1 0.5 0.3 1.7 0.2 9.4 0.6 2.7 2.3 11.3 0.1 0.7 0.1 0.2 0.3 0.7 15.2 0.0 0.1 0.1 6.0 0.2 0.2 0.0 2.2 2.5 0.3 0.0 0.0 0.0 0.2 0.0 0.2 5.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 2.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.1 0.2 1.4 0.1 0.3 0.6 0.0 0.1 0.0 0.1 45.1 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.1 0.1 0.9 0.2 0.1 0.0 0.0 0.0 23.9 0.1 0.6 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.0 15.4 15.8 99.3 30.4 15.1 6.8 7.2 11.2 10.6 9.4 11.3 15.2 7.7 6.4 3.2 31.3 9.6 0.6 3.4 0.0 0.0 101.4 3.1 7.4 2.8 0.0 1.3 1.8 16.7 0.0 2.9 0.6 0.0 0.5 27.1 1.2 6.3 6.5 214.1 0.4 318.3 0.4 0.2 4.7 10.7 2.6 1.3 5.2 1.8 1.2 0.5 249.0 372.1 5.0 4.1 1.9 1.4 28.0 1.2 2.1 0.0 28.1 1.2 3.0 4.1 271.9 11.5 1.5 0.1 0.4 0.5 0.8 0.2 2.0 3.7 7.0 0.0 5.1 17.6 4.3 7.1 0.4 0.1 0.3 2.0 2.5 1.0 0.9 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 3.7" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.1 6.6 7.0 0.2 4.3 0.7 1.8 2.3 10.4 6.0 0.0 1.5 1.7 3.7 7.3 0.5 7.7 2.0 0.6 3.6 0.8 2.2 1.0 3.7 0.1 0.0 1.2 0.5 2.8 1.2 3.5 0.6 0.4 3.0 1.5 4.3 0.5 1.8 0.2 0.7 2.4 0.7 3.5 1.8 0.8 1.6 6.1 0.2 2.9 0.2 0.1 0.6 0.1 6.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 2.7 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.1 0.1 0.0 0.4 0.9 0.0 0.0 0.2 55.5 0.5 3.6 4.7 2.1 0.3 10.1 1.1 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 4.3 2.3 10.4 3.6 0.8 0.0 1.2 0.4 3.5 6.1 6.0 0.6 3.2 36.2 7.8 0.6 0.9 0.8 4.6 2.2 33.3 7.2 1.8 2.3 10.0 9.1 1.8 35.5 0.9 0.5 3.0 0.0 7.2 4.9 4.3 40.1 2.4 59.4 2.7 251.2 2.3 0.2 3.4 5.1 3.3 12.6 1.7 0.0 3.4 0.2 8.4 354.1 3.8 2.0 0.8 4.0 8.3 4.4 2.1 5.4 126.5 0.5 4.0 0.0 197.5 29.9 3.8 5.6 27.1 0.1 1.7 9.5 2.7 9.5 12.9 0.0 0.2 8.6 1.0 3.7 0.5 1.0 0.3 1.7 9.6 7.6 0.9 CACNA1S "CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5" ENSG00000081248 "Calcium voltage-gated channel subunit alpha1 S" Q13698 1 201039512-201112451 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 86 "skeletal muscle: 254.9;tongue: 193.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Cone photoreceptor cells: 6.2;Late spermatids: 5.9;Skeletal myocytes: 6.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "BEWO: 1.1;HSkMC: 1.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Region enriched" "Detected in single" 8 "olfactory bulb: 2.6" "CAB009507, HPA048892, HPA056815" Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "CAB009507: AB_2069576, HPA048892: AB_2680548, HPA056815: AB_2683242" "unprognostic (2.14e-2)" "unprognostic (1.38e-1)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.52e-3)" "unprognostic (4.53e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (4.72e-3)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-1)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.9 1.5 0.0 254.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.0 193.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.6 0.2 0.8 0.2 0.1 1.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 6.3 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CADPS2 CAPS2 ENSG00000081803 "Calcium dependent secretion activator 2" Q86UW7 7 122318411-122886759 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 682.7;Microglial cells: 180.8;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 96.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 43.5;Karpas-707: 56.3;OE19: 63.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 159.9" HPA056398 Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA056398: AB_2683117" "unprognostic (1.93e-1)" "unprognostic (5.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.67e-3)" "unprognostic (8.69e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (1.33e-1)" "unprognostic (4.07e-1)" "unprognostic (4.33e-2)" "unprognostic (3.93e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.01e-7)" "unprognostic (9.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.71e-2)" "unprognostic (3.45e-2)" 10.3 21.1 9.2 4.5 16.3 0.1 18.3 96.2 30.9 29.8 5.8 10.7 12.6 35.0 30.3 4.5 11.0 15.6 10.2 14.2 14.4 38.3 13.2 18.0 3.5 4.9 40.1 9.9 26.0 12.0 13.8 6.0 7.9 19.4 10.7 7.2 48.3 18.5 2.4 4.0 10.0 21.7 6.2 6.7 20.0 4.0 17.4 4.9 18.3 7.8 3.8 9.3 8.5 18.7 0.0 0.1 3.4 0.0 5.1 5.2 0.3 0.5 13.5 2.9 13.4 0.1 12.6 0.0 0.0 6.4 0.4 0.1 0.4 1.9 1.3 0.0 11.1 4.4 0.1 25.1 16.9 0.0 0.2 5.5 2.4 2.3 1.7 11.8 43.5 0.0 0.0 56.3 0.2 30.9 0.0 0.1 12.6 63.6 21.4 0.0 0.0 23.2 0.6 14.3 20.5 0.0 0.6 24.4 1.2 3.2 9.5 0.1 12.5 4.7 3.1 0.1 8.9 16.8 0.7 0.0 18.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 16.3 96.2 30.9 14.2 14.4 4.9 40.1 7.9 6.2 17.4 18.7 29.3 9.6 43.9 85.2 3.1 2.2 7.9 7.3 10.2 0.6 36.7 22.4 12.9 11.5 14.4 40.5 0.0 0.4 0.5 4.3 17.6 4.4 8.5 4.8 13.5 24.7 4.8 0.0 682.7 11.1 0.5 13.0 42.3 11.2 1.3 10.1 14.3 12.5 0.4 3.3 14.2 13.2 10.2 3.1 1.4 6.8 9.6 0.6 3.6 180.8 0.0 27.2 0.0 111.1 11.0 4.8 3.7 10.1 15.7 13.4 5.7 7.9 9.4 1.5 0.0 6.9 6.2 0.7 4.2 6.2 1.4 0.3 0.7 11.3 8.0 8.5 CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359498-42412949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 279.2;skeletal muscle: 905.9;tongue: 377.4" "Group enriched" "Detected in many" 5 "Early spermatids: 512.5;Late spermatids: 183.6;Melanocytes: 482.0;Oligodendrocytes: 220.2" "Cancer enriched" "Detected in some" 10 "melanoma: 9.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 27 "SK-MEL-30: 238.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040052 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA040052: AB_2676821" "unprognostic (1.06e-2)" "unprognostic (1.31e-1)" "unprognostic (4.00e-2)" "unprognostic (8.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (2.11e-4)" "unprognostic (3.12e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-3)" "unprognostic (3.26e-2)" "unprognostic (3.91e-4)" "unprognostic (5.56e-3)" "unprognostic (2.43e-1)" "unprognostic (8.93e-3)" "unprognostic (1.38e-1)" 13.5 8.8 136.1 4.0 206.6 47.6 14.1 194.2 243.3 18.8 113.0 13.3 3.1 11.2 163.7 14.5 13.7 4.5 16.1 142.9 159.9 93.6 36.9 21.5 7.0 212.0 194.9 15.7 8.7 2.4 11.3 3.0 212.1 16.0 5.3 7.5 18.6 5.2 905.9 54.9 14.0 4.7 155.2 19.1 8.9 30.8 187.8 3.4 10.7 377.4 5.1 11.7 15.5 279.2 0.5 0.3 0.6 1.1 8.8 6.1 0.6 2.6 1.9 0.5 0.8 1.2 0.5 0.2 0.9 1.6 0.4 3.7 0.4 3.5 0.3 0.9 0.8 0.8 0.8 4.1 0.6 1.0 1.5 4.7 3.7 0.8 0.7 1.5 0.1 0.7 0.2 1.8 0.7 0.1 0.2 1.2 0.4 0.2 0.9 1.1 0.4 1.9 1.9 1.3 0.4 0.1 0.2 0.5 238.0 1.0 0.0 5.4 0.9 0.3 0.4 2.6 0.7 1.5 2.1 0.2 0.4 2.4 1.8 0.5 1.0 0.1 0.7 0.2 0.8 0.3 0.1 0.3 0.5 0.5 0.1 0.9 0.9 0.6 0.1 0.5 0.4 0.6 136.1 206.6 194.2 243.3 142.9 159.9 212.0 194.9 212.1 155.2 187.8 279.2 0.5 12.8 34.5 16.0 2.9 20.1 0.8 2.2 3.4 2.2 0.4 0.3 0.4 1.5 4.4 1.8 2.1 0.7 1.4 2.0 1.9 0.1 512.5 0.5 0.6 2.2 0.0 0.0 4.0 0.0 0.6 1.6 3.6 0.7 1.3 0.4 2.2 8.7 32.7 0.0 5.2 1.8 2.0 4.4 11.6 183.6 5.3 2.9 482.0 13.1 2.5 3.7 2.1 4.5 220.2 0.0 5.4 3.4 0.6 0.9 2.4 59.5 2.6 3.9 0.0 13.8 1.6 15.9 4.7 1.6 8.5 3.3 1.8 1.2 2.3 0.8 CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 14.1;Hofbauer cells: 21.2;Horizontal cells: 15.2;Kupffer cells: 18.8;Langerhans cells: 12.9;Macrophages: 22.3;monocytes: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 22.5;HMC-1: 69.7;NB-4: 50.0;THP-1: 63.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" 1.2 1.3 0.5 4.7 0.5 13.0 1.2 2.5 1.0 2.0 0.3 1.0 1.3 0.8 0.4 1.0 1.8 1.0 0.5 0.5 0.7 1.0 0.9 3.4 1.2 1.9 0.9 0.3 0.5 0.1 0.8 0.9 1.3 1.8 0.4 0.2 1.1 1.0 0.2 2.7 1.8 1.1 1.4 9.9 0.6 0.4 1.1 0.4 0.4 0.0 1.5 1.2 1.1 1.7 0.1 0.0 0.3 0.0 0.0 0.0 4.6 9.5 0.3 0.2 0.0 0.7 0.0 0.0 0.1 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.5 0.1 6.8 4.9 12.2 69.7 0.0 0.1 0.2 0.2 0.0 0.1 0.0 5.3 0.0 0.0 0.2 0.0 50.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 12.3 0.0 16.0 0.1 0.0 4.1 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 16.0 0.0 6.9 34.5 11.5 0.0 57.6 0.9 0.0 0.0 0.0 26.0 0.0 0.0 0.0 2.3 0.7 50.5 0.1 0.5 14.1 0.5 0.5 2.5 1.0 0.5 0.7 1.9 0.9 1.3 1.4 1.1 1.7 0.8 0.0 4.6 4.6 1.1 1.8 0.6 0.3 3.4 0.2 4.2 4.3 2.6 0.0 4.9 3.7 0.0 0.4 2.2 0.4 1.9 0.1 1.0 1.2 14.1 1.1 0.0 2.5 2.1 0.0 0.4 2.1 1.5 1.4 10.8 0.4 0.7 0.1 21.2 15.2 1.1 0.0 0.0 18.8 12.9 6.9 0.3 22.3 1.8 6.5 16.3 4.6 3.1 0.0 0.2 0.0 0.1 0.0 1.4 0.1 0.0 0.3 0.6 0.9 0.0 0.3 1.5 1.0 1.5 0.9 1.7 0.4 1.4 0.2 0.2 0.6 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 45.7 21.7 7.0 69.4 7.2 48.5 44.4 7.4 12.4 26.4 8.6 27.6 62.4 18.4 33.1 47.7 34.9 50.1 17.8 7.5 8.0 33.3 54.1 61.3 80.2 9.7 8.1 43.2 52.5 4.7 11.0 70.2 8.7 21.7 30.7 2.0 55.2 15.5 7.5 46.7 58.8 32.2 8.3 71.1 42.4 4.9 9.0 57.2 15.6 18.1 82.1 76.5 30.5 8.7 33.8 9.5 0.0 12.9 58.2 140.4 27.8 68.0 103.2 80.5 117.0 22.4 128.5 22.3 123.1 71.5 110.4 52.7 0.0 94.3 78.8 22.4 0.4 53.1 7.4 55.8 158.2 48.5 19.2 122.6 127.0 97.9 144.4 104.7 143.8 0.5 1.3 0.0 64.4 2.8 26.1 46.7 0.0 71.6 28.2 21.4 21.5 14.2 64.9 46.2 0.6 0.4 60.8 31.6 49.3 0.7 11.9 62.5 93.2 84.4 30.4 80.8 40.5 0.0 0.0 0.3 42.2 105.5 63.4 136.4 292.0 50.6 208.9 312.9 224.8 141.9 155.6 193.9 205.5 144.4 93.4 138.5 667.2 226.2 255.4 35.4 257.9 410.9 7.0 7.2 7.4 12.4 7.5 8.0 9.7 8.1 8.7 8.3 9.0 8.7 78.1 60.9 60.8 0.3 87.4 55.8 63.3 130.1 21.1 0.0 40.8 48.4 5.6 47.1 107.0 22.0 0.0 129.1 80.4 12.4 15.6 157.5 0.6 35.9 27.7 73.0 20.9 12.4 0.0 189.9 103.0 53.6 33.1 45.7 34.8 32.6 82.1 34.7 116.7 0.0 0.2 37.8 73.2 168.0 81.2 2.1 29.2 105.2 30.2 23.4 141.5 1.9 177.1 1.5 0.2 148.5 8.6 20.7 50.5 31.1 85.4 41.1 86.1 0.4 6.6 38.1 34.2 0.2 0.5 25.8 45.9 115.9 102.1 36.8 32.9 80.0 CASQ1 "CASQ, PDIB1" ENSG00000143318 "Calsequestrin 1" P31415 1 160190575-160201886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 64 "skeletal muscle: 4442.6;tongue: 1892.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 17.6;Rod photoreceptor cells: 25.2;Skeletal myocytes: 20.6" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 19.3;HDLM-2: 38.5;RT4: 67.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007845, CAB015170, HPA026823" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 270000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Mitochondria" "CAB015170: AB_2071451, HPA007845: AB_1078388, HPA026823: AB_10603557" "unprognostic (1.87e-2)" "unprognostic (3.97e-3)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (6.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.65e-3)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (2.87e-2)" "unprognostic (3.01e-2)" "unprognostic (3.21e-3)" "unprognostic (9.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "prognostic favorable (8.93e-5)" 0.9 0.4 5.1 0.8 6.0 1.5 1.4 4.9 10.0 0.5 3.3 3.3 0.5 1.7 0.3 43.1 1.9 1.2 44.9 6.5 3.1 0.3 0.4 0.7 3.0 3.7 3.9 0.4 0.3 0.2 1.0 6.2 3.2 16.2 0.5 49.7 16.7 5.0 4442.6 1.0 1.9 7.4 3.1 1.3 0.8 5.7 3.6 0.5 0.6 1892.7 1.0 5.7 0.9 6.2 0.0 0.0 0.5 0.0 0.2 0.0 19.3 0.0 0.2 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 38.5 0.4 0.1 0.0 0.0 0.1 0.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.7 0.4 0.1 0.0 0.2 0.3 0.2 0.0 67.4 0.0 0.1 0.3 0.2 0.0 3.5 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.7 0.8 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 6.0 4.9 10.0 6.5 3.1 3.7 3.9 3.2 3.1 3.6 6.2 0.1 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 1.9 0.7 0.9 17.6 0.0 0.0 0.0 2.1 3.0 0.1 0.0 0.0 0.1 3.0 0.1 0.1 0.2 0.0 0.0 2.0 0.0 4.9 0.3 0.0 0.1 3.8 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.3 0.6 0.6 0.2 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 25.2 0.0 20.6 0.6 1.2 1.9 0.0 0.0 4.5 0.1 0.1 0.0 0.3 CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 182.7;tongue: 72.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 22.9;Early spermatids: 4.2;Sertoli cells: 6.6;Skeletal myocytes: 11.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017518, CAB018557, HPA054488" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 5.7 0.1 0.1 27.4 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 2.5 0.2 182.7 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.1 72.8 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 11.0 2.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 CAVIN4 "cavin-4, MURC" ENSG00000170681 "Caveolae associated protein 4" Q5BKX8 9 100578079-100588389 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 276.1;tongue: 92.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.5;Endometrial ciliated cells: 1.2;Endometrial stromal cells: 1.8;Glandular and luminal cells: 1.9;Granulosa cells: 1.8;Pancreatic endocrine cells: 1.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.9;SCLC-21H: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020973, HPA020987, HPA021021" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA020973: AB_1853079, HPA020987: AB_1853080, HPA021021: AB_1853082" "unprognostic (9.54e-5)" "unprognostic (1.68e-2)" "unprognostic (2.50e-2)" "unprognostic (3.76e-2)" "unprognostic (4.92e-2)" "unprognostic (4.56e-3)" "unprognostic (1.14e-4)" "unprognostic (3.36e-2)" "unprognostic (2.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (4.02e-1)" "unprognostic (1.74e-8)" "unprognostic (1.14e-1)" "unprognostic (3.39e-1)" "unprognostic (3.68e-3)" "unprognostic (1.55e-3)" 0.2 0.1 1.6 0.2 2.9 0.1 0.1 2.0 5.6 0.4 0.4 0.4 0.0 0.5 0.1 4.3 0.1 0.3 45.9 1.7 2.5 0.2 0.2 0.4 0.1 2.7 2.7 0.2 0.1 0.0 0.2 0.3 2.7 4.5 0.1 0.3 2.4 0.1 276.1 0.2 0.1 0.3 1.8 0.1 0.3 3.7 2.7 0.4 0.5 92.4 0.1 0.3 0.2 3.5 0.5 0.3 6.1 2.2 1.4 2.0 4.3 1.1 0.9 0.8 1.0 0.0 0.4 0.2 0.3 0.6 2.1 0.3 3.1 0.1 1.7 1.4 2.0 0.1 1.0 0.0 0.4 0.2 0.4 5.0 0.3 0.8 0.5 1.5 1.1 1.5 0.2 0.2 3.9 0.1 1.8 0.3 8.9 1.0 0.7 2.6 5.8 0.0 0.8 0.3 13.2 3.4 0.2 0.2 1.1 4.1 0.1 0.2 1.1 1.5 1.2 1.0 1.0 0.3 1.1 0.6 1.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.9 2.0 5.6 1.7 2.5 2.7 2.7 2.7 1.8 2.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.7 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.9 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 84.7" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA044124: AB_10969197" "unprognostic (1.88e-1)" "unprognostic (2.05e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-3)" "unprognostic (2.13e-2)" "unprognostic (1.10e-1)" "unprognostic (8.63e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-2)" "unprognostic (2.23e-2)" "unprognostic (7.33e-2)" "prognostic favorable (3.42e-9)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (2.18e-2)" 8.3 9.3 13.5 2.7 13.0 2.7 8.8 14.2 16.5 14.2 22.1 17.3 4.9 12.8 11.1 8.3 34.2 12.4 7.4 13.2 13.5 23.6 2.9 10.7 2.0 13.7 14.6 11.7 5.1 10.0 12.7 8.5 12.6 10.0 5.9 84.7 3.3 12.5 2.5 2.3 5.0 15.4 12.0 3.3 8.2 4.9 14.7 1.2 8.2 11.1 1.4 9.3 6.4 12.7 5.4 11.3 15.6 7.0 18.4 34.4 3.8 6.8 11.5 12.7 15.5 5.1 13.2 0.5 7.3 13.1 27.7 3.4 13.1 8.7 15.9 0.0 7.3 5.5 10.1 7.1 13.5 0.5 0.1 25.0 22.8 20.7 15.5 23.3 5.9 0.2 14.7 0.4 24.4 3.9 0.2 0.9 25.9 0.2 23.3 3.5 4.9 1.1 32.1 2.6 9.7 11.1 4.3 3.1 32.2 14.6 4.9 1.3 2.2 20.2 12.0 8.6 14.4 0.4 0.5 0.3 24.3 0.3 13.1 1.9 2.4 0.2 0.4 1.6 0.6 0.3 0.3 0.1 3.8 0.3 0.2 0.4 4.8 0.9 0.8 0.2 0.9 0.6 13.5 13.0 14.2 16.5 13.2 13.5 13.7 14.6 12.6 12.0 14.7 12.7 8.4 12.8 14.6 39.8 0.7 2.2 5.6 5.7 14.2 15.1 6.5 9.0 22.9 10.0 23.5 25.8 569.2 10.2 0.3 0.8 33.2 6.6 12.0 96.8 14.0 7.0 6.0 2.7 20.9 0.9 3.1 18.7 4.1 9.0 0.0 15.2 8.9 1.6 5.0 8.4 43.4 0.9 8.2 5.7 4.6 6.7 9.3 4.4 12.4 16.9 1.2 18.4 0.0 62.8 19.5 1.0 0.5 16.6 1.3 4.4 2.1 57.1 128.4 136.4 6.6 14.7 17.7 2.6 0.7 6.4 1.3 1.5 1.9 12.9 2.9 4.0 CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050086 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 74.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.5;Bipolar cells: 28.1;Cardiomyocytes: 118.2;Cholangiocytes: 27.1;Early spermatids: 37.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 15.0" "Group enriched" "Detected in many" 9 "B-cells: 8.1;T-cells: 15.0" "Cell line enhanced" "Detected in some" "CACO-2: 4.6;Daudi: 3.0;HEL: 6.9;RH-30: 3.6;U-266/70: 4.3;U-698: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA012718: AB_2072055" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "unprognostic (8.62e-3)" "unprognostic (4.25e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.33e-2)" "unprognostic (8.03e-3)" "unprognostic (7.71e-8)" "unprognostic (2.50e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-1)" 1.5 0.3 0.8 0.5 0.4 1.3 0.7 0.9 1.0 0.6 0.8 0.2 0.1 0.6 0.2 0.4 0.4 1.7 74.6 0.3 0.6 0.1 0.3 2.0 1.5 1.2 1.1 1.0 5.8 0.1 0.0 1.2 1.4 0.3 0.2 1.1 0.1 0.2 17.1 0.5 0.2 0.2 1.6 0.7 0.2 1.5 1.0 1.5 0.3 3.5 1.1 0.3 0.1 1.8 0.1 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.1 4.6 0.3 3.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 6.9 0.2 0.0 0.0 1.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.1 0.2 2.4 0.4 0.5 0.1 3.6 1.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.7 0.2 0.3 0.0 0.2 0.1 0.2 0.0 4.3 0.1 6.1 0.2 0.3 0.4 0.4 0.0 0.2 0.3 0.0 0.2 7.3 2.2 1.5 0.0 8.1 6.5 5.1 0.3 1.2 0.0 0.0 15.0 0.4 0.8 0.4 0.9 1.0 0.3 0.6 1.2 1.1 1.4 1.6 1.0 1.8 4.5 6.4 29.5 5.5 11.0 0.1 0.0 0.0 0.6 28.1 0.2 0.3 118.2 27.1 0.6 0.0 0.0 0.0 2.8 0.1 0.0 4.6 37.3 0.2 1.1 6.7 0.0 0.4 3.6 1.3 0.2 2.9 0.0 1.1 6.3 0.0 0.4 0.3 0.0 6.7 3.1 0.1 0.0 1.0 1.0 16.8 1.2 3.9 1.8 8.4 0.1 5.5 1.0 0.5 0.8 0.2 0.0 1.9 2.6 0.0 0.2 0.1 1.5 0.6 6.6 2.8 5.4 0.1 1.1 0.0 0.1 0.0 10.3 1.1 0.2 0.2 CCDC28B "MGC1203, RP4-622L5.5" ENSG00000160050 "Coiled-coil domain containing 28B" Q9BUN5 1 32200595-32205453 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 225.3;tongue: 75.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 90.1;monocytes: 65.5;NK-cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 124.9" "Low region specificity" "Detected in all" HPA028589 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA028589: AB_10602175" "prognostic favorable (2.92e-4)" "unprognostic (6.01e-3)" "unprognostic (1.04e-1)" "unprognostic (2.61e-2)" "unprognostic (2.59e-3)" "unprognostic (5.18e-2)" "unprognostic (7.50e-3)" "unprognostic (7.87e-2)" "unprognostic (5.15e-2)" "unprognostic (1.79e-2)" "prognostic favorable (1.10e-5)" "unprognostic (2.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.44e-2)" "unprognostic (1.67e-1)" "unprognostic (7.83e-2)" "unprognostic (1.07e-2)" 3.8 13.9 14.3 7.1 12.9 6.8 3.3 14.5 18.7 6.6 12.1 7.6 1.7 5.3 1.7 5.5 5.6 4.9 20.8 13.2 13.3 6.5 2.4 3.9 14.1 12.8 13.3 6.0 5.6 19.2 21.1 5.0 12.2 5.3 2.5 5.1 3.6 4.1 225.3 2.7 4.3 6.2 12.6 5.4 3.9 20.8 15.8 12.4 6.3 75.0 9.5 5.0 4.3 13.1 10.6 4.5 20.8 22.7 6.8 8.5 1.2 8.2 11.9 13.2 9.3 9.0 13.2 23.3 14.2 9.3 1.7 0.5 18.7 9.2 2.6 27.0 25.5 29.9 20.7 4.1 10.1 0.2 13.7 10.5 3.5 15.5 0.2 9.2 19.3 40.5 20.5 0.5 9.6 1.3 43.2 8.7 29.4 2.8 5.8 46.5 10.4 19.2 12.2 0.0 45.6 22.9 11.9 3.2 16.3 12.0 12.0 11.5 11.4 7.1 9.5 8.7 7.6 2.1 1.6 0.9 11.7 43.9 10.3 9.7 13.7 3.0 36.3 6.9 17.6 22.0 19.4 34.3 30.6 31.5 28.4 29.3 1.9 46.7 2.1 37.1 26.9 21.8 14.3 12.9 14.5 18.7 13.2 13.3 12.8 13.3 12.2 12.6 15.8 13.1 10.5 0.0 6.1 3.9 11.1 9.1 4.4 17.9 5.7 33.3 9.6 12.7 16.1 11.5 5.3 12.9 22.9 1.9 25.8 1.6 35.2 17.5 13.8 8.1 18.1 15.2 90.1 30.7 3.1 7.6 4.0 19.0 5.6 5.1 3.8 8.0 12.1 0.6 11.7 23.5 3.9 5.7 54.9 4.2 39.2 32.8 20.2 5.7 17.8 0.0 65.5 23.9 106.1 5.5 1.7 7.8 1.7 17.0 1.8 3.4 0.3 4.9 4.2 45.9 0.0 12.5 18.0 3.9 13.3 3.5 7.7 2.2 15.3 48.1 3.4 2.6 CCDC63 "FLJ35843, ODA5" ENSG00000173093 "Coiled-coil domain containing 63" Q8NA47 12 110846769-110907535 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.3" "Group enriched" "Detected in some" 32 "Early spermatids: 305.6;Late spermatids: 241.7" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "MCF7: 4.4" HPA061568 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No NA "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Vesicles "HPA061568: AB_2684561" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.09e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 305.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 241.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 4.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 21.7;HMC-1: 83.3;Karpas-707: 22.0;THP-1: 34.5;U-937: 25.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" 8.5 6.7 14.9 15.1 15.1 47.6 5.3 20.1 21.6 5.6 15.3 17.8 4.0 3.5 0.3 12.9 6.5 8.5 5.5 15.3 15.0 6.5 7.3 21.1 28.6 17.2 15.5 3.1 4.1 0.9 4.5 1.7 17.5 7.8 3.6 1.4 14.4 2.5 1.2 4.5 34.1 1.2 15.4 86.1 8.9 17.4 15.4 17.4 5.4 0.8 13.8 8.3 7.7 15.9 0.3 1.3 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 3.4 19.7 2.9 1.1 0.5 1.6 0.1 0.6 0.0 21.7 0.0 15.0 4.6 1.1 0.8 9.4 83.3 0.0 0.0 0.2 0.0 1.3 0.5 6.3 0.5 22.0 0.7 0.9 12.7 7.7 0.7 3.7 0.5 11.9 0.3 18.5 0.3 0.3 4.8 0.0 0.0 0.5 1.1 0.1 2.6 34.5 0.0 0.0 0.7 0.1 0.2 4.7 1.5 15.8 1.0 25.3 0.4 2.9 4.6 6.7 3.5 3.6 1.0 1.6 2.0 2.9 1.6 2.0 1.8 2.2 9.2 6.5 2.5 2.7 0.6 1.3 14.9 15.1 20.1 21.6 15.3 15.0 17.2 15.5 17.5 15.4 15.4 15.9 3.3 0.0 10.7 5.2 30.3 2.7 4.5 10.5 0.6 45.2 5.7 4.8 13.5 4.3 9.9 9.2 0.0 2.9 34.9 46.0 0.0 12.8 11.1 8.7 2.6 4.4 18.0 7.0 2.6 28.9 5.8 3.1 51.0 6.8 26.6 2.2 6.1 10.4 14.5 0.0 2.0 24.4 8.2 26.0 26.6 15.8 1.5 27.3 5.4 12.2 35.0 15.4 64.9 2.0 0.6 35.0 33.2 0.7 24.9 2.9 36.1 3.2 22.7 4.7 0.0 2.8 2.8 13.7 8.7 2.0 1.6 1.4 31.7 10.0 32.4 15.7 CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2726.3" "Cell type enriched" "Detected in many" 8 "Endothelial cells: 1213.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.1;K-562: 1.2" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" NA NA 198000 920000 "Cluster 16: Immune cells - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051210: AB_2681390" "unprognostic (3.06e-3)" "unprognostic (7.19e-3)" "unprognostic (9.89e-2)" "unprognostic (5.50e-2)" "unprognostic (4.51e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" "unprognostic (8.07e-2)" "unprognostic (4.15e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (8.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 173.7 46.9 0.0 269.5 0.1 0.0 180.7 0.1 0.3 154.7 0.6 111.7 46.3 75.6 34.1 128.2 253.3 80.8 41.7 0.1 0.1 75.1 66.0 196.4 2726.3 0.4 0.0 33.9 15.3 0.8 2.5 1.7 0.2 38.2 135.7 0.0 21.5 19.0 6.8 46.4 498.8 69.0 0.0 336.8 60.9 10.3 0.1 28.8 519.4 30.6 998.8 74.1 50.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.7 0.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.2 58.4 22.4 53.3 0.0 1.9 145.3 2.4 3.8 1.8 0.0 13.5 4.3 10.1 0.0 13.0 1.8 0.0 0.2 1.4 0.2 0.0 10.0 5.7 0.1 0.3 1213.6 0.0 2.7 0.0 3.6 0.2 22.9 0.0 0.2 11.4 0.0 107.1 0.5 0.6 0.0 0.0 2.1 0.0 1.8 148.8 11.0 0.6 6.5 144.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 29.6 1.5 0.0 0.0 10.2 0.0 0.0 3.4 120.0 0.2 0.3 11.5 137.7 0.3 9.2 0.0 0.0 0.4 CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 165.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 42.6;ASC TERT1: 113.8;HeLa: 62.7;HSkMC: 46.5;U-2197: 375.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 394.6 41.5 1.8 0.7 2.0 0.2 116.5 0.9 2.9 355.7 0.7 23.6 0.7 35.3 0.7 25.4 39.0 7.7 161.1 1.6 1.3 0.7 5.6 136.4 1.9 1.4 1.4 147.1 4.4 0.6 0.8 1.4 1.4 37.0 1.6 0.1 30.7 25.5 39.2 197.1 11.5 6.5 1.0 4.0 11.4 33.1 1.4 1.3 14.2 5.1 0.4 36.7 111.6 1.5 0.0 3.7 0.1 0.0 42.6 113.8 0.0 0.2 1.2 0.1 0.2 0.0 0.0 0.1 0.5 0.7 3.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 62.7 0.0 0.1 0.1 0.1 46.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.1 0.3 0.0 1.9 0.2 0.0 0.1 0.2 375.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.0 0.9 2.9 1.6 1.3 1.4 1.4 1.4 1.0 1.4 1.5 25.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.4;fallopian tube: 108.8" "Cell type enhanced" "Detected in many" "Astrocytes: 170.7;Endometrial ciliated cells: 136.4;Excitatory neurons: 70.2;Inhibitory neurons: 63.8;Respiratory ciliated cells: 358.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 5.7;Daudi: 6.5;WM-115: 4.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" HPA011218 Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA011218: AB_1078886" "unprognostic (4.38e-4)" "unprognostic (9.18e-2)" "unprognostic (8.16e-3)" "unprognostic (8.08e-3)" "unprognostic (5.23e-2)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.70e-3)" "unprognostic (3.51e-3)" 1.2 0.9 4.6 0.9 3.9 0.9 4.1 4.2 5.0 4.6 46.4 7.5 1.9 1.7 3.2 0.5 108.8 0.2 1.7 5.7 2.3 2.0 2.1 14.2 0.7 9.8 20.4 2.4 1.0 0.0 1.6 0.1 7.8 0.9 1.6 6.7 0.4 0.6 0.8 0.7 4.7 3.2 7.0 0.2 9.3 0.5 5.6 0.1 2.6 0.4 0.9 0.7 0.8 5.6 0.1 0.3 5.7 0.7 1.5 2.1 0.1 0.3 0.3 0.3 0.1 0.0 0.1 6.5 0.0 0.3 0.6 0.0 1.4 0.0 0.2 0.4 0.8 0.0 0.2 0.7 0.0 0.1 0.2 0.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 1.1 2.2 0.4 0.0 0.0 0.2 0.1 0.1 0.4 2.1 0.0 0.4 0.3 0.8 0.0 0.0 0.2 1.0 0.2 1.3 0.0 0.0 0.0 2.1 0.1 0.1 4.9 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 2.9 0.1 0.0 0.9 0.3 0.1 0.1 0.3 0.1 4.6 3.9 4.2 5.0 5.7 2.3 9.8 20.4 7.8 7.0 5.6 5.6 2.5 3.2 10.4 170.7 1.7 2.7 1.6 9.5 2.8 6.4 1.8 3.4 1.4 5.7 37.6 0.0 0.0 0.6 2.8 2.0 5.9 0.7 8.5 136.4 1.4 1.8 29.9 0.0 70.2 0.6 0.3 2.8 15.3 2.9 3.8 3.8 0.0 2.9 0.1 0.0 63.8 4.9 8.2 0.0 2.7 3.8 2.8 0.7 8.8 16.9 0.0 10.2 6.2 4.0 4.3 0.2 3.3 1.5 1.4 0.7 5.0 6.2 358.4 1.3 6.6 2.2 8.8 1.2 3.2 0.6 2.0 0.3 2.4 1.4 3.0 0.7 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CEP85 "CCDC21, DKFZP434L0117" ENSG00000130695 "Centrosomal protein 85" Q6P2H3 1 26234200-26278808 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.9;tongue: 65.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.0;Oligodendrocytes: 28.8;Spermatocytes: 40.9;Spermatogonia: 34.2;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028252 Approved Approved "Nucleoli,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Golgi apparatus" "Centrosome, Cytosol" "HPA028252: AB_1846142" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (1.74e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (5.30e-3)" "prognostic unfavorable (4.39e-6)" "unprognostic (3.72e-2)" "unprognostic (5.30e-2)" "unprognostic (8.24e-2)" "unprognostic (9.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (7.33e-3)" "unprognostic (5.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.60e-2)" 2.8 3.5 3.9 5.3 8.3 20.8 3.8 5.6 6.7 4.1 3.7 5.4 3.4 3.2 3.2 8.6 2.7 2.7 25.5 4.3 5.9 6.0 5.8 4.7 6.9 7.1 6.8 3.3 5.0 8.8 6.1 3.2 8.9 2.9 6.0 14.1 5.3 2.4 132.9 9.8 5.2 3.7 3.7 6.3 4.7 31.1 7.1 13.6 7.8 65.9 7.8 3.2 6.2 14.3 29.6 12.5 30.2 22.6 7.3 8.9 52.5 18.8 11.5 31.9 28.5 17.4 28.2 34.3 20.1 9.2 14.6 25.5 41.0 14.4 29.9 23.5 20.9 49.7 31.9 19.4 6.6 46.2 43.8 3.8 13.7 24.9 16.4 12.8 14.5 47.7 57.4 39.9 19.2 9.8 38.7 35.2 23.0 17.4 20.8 39.8 31.3 29.7 10.4 5.5 41.4 16.7 24.5 19.8 15.7 21.5 14.5 26.4 14.3 17.1 26.7 19.3 24.7 30.0 48.4 38.9 9.8 65.2 27.5 5.0 6.4 19.2 3.5 6.1 2.8 2.6 2.6 2.7 4.9 1.8 2.2 3.5 0.6 2.3 7.4 2.1 3.6 3.6 3.9 8.3 5.6 6.7 4.3 5.9 7.1 6.8 8.9 3.7 7.1 14.3 1.0 0.0 2.2 3.6 2.7 6.9 4.0 2.5 6.2 11.2 3.7 2.9 29.0 1.5 3.7 5.5 12.5 3.4 5.1 6.9 7.9 1.7 1.0 3.4 2.3 2.0 1.8 16.8 12.8 1.3 3.9 2.3 3.6 4.9 2.5 9.1 1.4 3.1 4.8 0.0 9.9 3.7 2.0 5.0 3.7 2.9 1.5 4.3 1.8 4.7 4.0 1.8 2.1 3.0 28.8 2.7 3.4 0.4 4.4 2.5 2.3 1.1 2.0 11.1 0.0 2.4 2.3 40.9 34.2 8.6 6.1 41.7 3.4 2.3 4.5 4.5 CFAP20 "C16orf80, fSAP23, GTL3" ENSG00000070761 "Cilia and flagella associated protein 20" Q9Y6A4 16 58113592-58129381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 336.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018195 Uncertain Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA018195: AB_1850408" "unprognostic (9.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.80e-1)" "unprognostic (7.45e-2)" "unprognostic (2.27e-1)" "unprognostic (7.14e-3)" "unprognostic (9.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-1)" "unprognostic (2.86e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-2)" "unprognostic (9.72e-2)" "unprognostic (9.71e-2)" "unprognostic (7.58e-3)" "unprognostic (1.47e-1)" 20.3 23.8 34.9 15.6 36.9 26.0 20.9 35.2 37.9 20.7 33.8 16.8 17.3 20.1 23.1 18.9 36.2 18.0 43.1 35.5 38.2 20.6 33.8 20.5 25.5 33.3 35.0 31.3 14.6 34.7 30.9 30.2 35.1 18.6 16.1 28.5 17.5 17.8 12.1 20.8 16.6 17.5 37.8 18.1 16.4 30.8 35.8 39.3 26.5 20.0 21.9 18.1 17.8 38.1 58.1 45.6 75.5 40.9 27.6 22.0 59.2 53.7 37.4 83.3 53.7 73.3 61.4 60.1 75.5 36.4 37.8 58.0 70.7 53.3 82.2 34.5 75.0 34.1 25.3 97.7 32.1 51.7 64.9 24.9 36.3 53.1 47.9 31.8 51.6 92.5 57.2 28.0 66.3 43.7 147.4 104.2 69.5 39.7 91.6 141.5 94.3 56.7 46.8 35.6 68.7 61.2 95.7 36.9 54.0 51.8 32.0 63.3 36.1 51.0 67.0 56.3 62.1 33.7 33.5 115.1 33.3 53.5 70.0 88.6 29.6 52.9 46.4 30.2 45.5 55.0 48.1 49.6 33.9 49.7 64.0 54.3 24.8 66.6 31.1 56.8 94.9 52.5 34.9 36.9 35.2 37.9 35.5 38.2 33.3 35.0 35.1 37.8 35.8 38.1 70.9 12.8 20.3 10.4 21.8 0.0 38.5 0.0 60.3 28.7 28.7 50.9 51.7 30.0 16.1 20.2 33.3 101.9 29.3 7.4 56.7 36.7 336.7 60.1 29.2 58.7 24.3 19.1 7.3 16.5 75.3 40.8 18.8 22.0 12.6 22.5 30.4 35.7 35.1 18.5 7.7 19.6 0.0 11.4 0.0 137.7 33.8 17.4 0.0 3.7 17.4 32.3 23.7 16.6 21.0 22.6 17.2 31.2 19.1 30.8 23.5 34.7 33.5 38.8 19.7 60.9 30.3 109.7 30.3 35.6 0.0 65.9 31.6 38.5 17.2 19.5 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CGAS "C6orf150, MB21D1" ENSG00000164430 "Cyclic GMP-AMP synthase" Q8N884 6 73413515-73452297 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.0" "Cell type enhanced" "Detected in some" "Adipocytes: 10.2;dendritic cells: 12.0;Glandular and luminal cells: 12.5;Hofbauer cells: 12.4;Macrophages: 10.0;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 37.1;RH-30: 43.8;RPMI-8226: 45.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031700, HPA031702" Enhanced Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031700: AB_10601693, HPA031702: AB_2673999" "unprognostic (2.49e-1)" "unprognostic (2.36e-1)" "unprognostic (4.61e-2)" "unprognostic (4.95e-2)" "unprognostic (2.49e-2)" "unprognostic (1.81e-1)" "unprognostic (4.84e-3)" "unprognostic (1.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.25e-2)" "unprognostic (2.20e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.27e-7)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-1)" 2.9 1.1 1.7 6.4 2.1 14.0 1.7 2.2 3.0 2.4 1.7 1.9 2.7 1.9 0.6 2.3 1.8 2.6 1.5 1.9 2.0 1.1 0.8 3.5 7.4 2.6 2.2 1.2 1.2 0.6 0.6 3.1 2.6 1.9 1.8 0.2 1.8 1.8 0.5 1.1 2.5 2.0 2.4 5.2 2.3 1.0 3.0 2.3 1.6 0.9 4.7 4.3 2.1 3.4 19.9 5.8 0.1 0.2 1.2 2.7 0.1 10.1 3.7 11.3 12.6 20.7 14.2 0.2 20.9 4.3 6.3 10.1 9.8 0.2 12.0 31.9 0.0 16.9 8.2 0.1 4.0 12.3 11.5 1.6 3.2 11.8 0.1 0.0 3.5 0.1 0.0 37.1 8.7 8.0 0.0 27.1 6.2 2.4 11.2 23.4 43.8 45.2 0.0 7.3 0.3 0.1 17.3 0.4 10.2 0.2 0.0 33.9 5.0 0.0 9.1 8.5 0.2 8.1 19.8 0.2 0.1 17.5 11.4 26.3 12.7 19.0 6.0 17.5 4.7 8.4 7.9 5.9 7.5 6.7 1.8 3.4 8.5 4.2 11.6 17.6 8.0 6.0 1.7 2.1 2.2 3.0 1.9 2.0 2.6 2.2 2.6 2.4 3.0 3.4 10.2 3.2 4.8 0.0 4.7 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.6 0.0 0.0 0.2 12.0 0.0 0.0 2.0 0.0 8.4 8.5 6.0 0.0 0.0 0.0 3.9 0.7 2.3 0.0 12.5 5.1 1.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 5.9 0.0 0.0 3.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.3 8.0 0.7 0.0 0.0 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "Muller glia cells: 114.4;NK-cells: 233.8;Plasma cells: 79.3;Sertoli cells: 92.1;Theca cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Cell line enhanced" "Detected in many" "ASC diff: 57.7;ASC TERT1: 58.8;HEL: 48.2;HHSteC: 118.4;HMC-1: 55.4;HSkMC: 62.3;U-266/70: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" 7.7 2.7 17.8 8.1 13.7 16.8 6.3 16.7 14.6 5.7 6.0 3.0 2.1 8.4 1.4 1.1 2.1 1.7 5.6 9.7 13.4 8.4 1.3 7.5 7.7 31.0 18.4 4.9 1.3 0.9 6.9 10.3 28.1 7.4 1.1 11.0 2.7 9.9 1.6 4.4 7.5 3.7 21.4 18.2 3.4 1.7 28.7 14.5 6.7 0.8 5.4 7.1 7.6 48.4 0.0 0.3 3.1 2.6 57.7 58.8 0.2 3.3 9.5 2.3 2.1 0.0 0.0 0.6 2.0 2.3 3.1 0.1 2.3 8.2 1.2 0.8 1.5 48.2 0.1 0.0 118.4 1.2 55.4 62.3 9.7 3.1 10.1 3.6 3.6 7.2 5.5 2.9 15.4 0.0 9.1 12.2 16.5 0.0 8.0 0.5 1.0 0.1 1.7 2.2 3.7 0.0 0.7 0.0 5.6 2.9 0.0 1.9 12.3 7.0 4.1 9.5 13.9 52.4 0.8 3.3 13.8 9.3 37.4 0.7 0.5 0.7 0.3 4.3 0.0 1.1 0.1 0.2 1.6 0.8 0.6 0.5 0.3 4.9 11.4 0.1 0.5 0.9 17.8 13.7 16.7 14.6 9.7 13.4 31.0 18.4 28.1 21.4 28.7 48.4 11.3 0.0 0.0 3.6 17.7 2.4 7.3 2.5 0.0 25.0 2.8 2.7 1.4 0.0 1.8 3.7 2.1 0.6 41.9 0.0 0.0 0.4 0.2 5.7 29.8 9.4 0.0 39.1 6.8 0.2 0.6 14.4 2.0 6.5 11.4 12.5 3.6 0.4 2.8 1.7 8.1 0.0 0.0 10.3 32.2 1.3 12.8 20.2 17.8 1.0 13.6 114.4 233.8 2.5 6.1 5.9 0.0 2.2 79.3 13.1 0.0 0.0 0.1 23.8 92.1 0.8 20.2 0.0 2.2 0.1 0.6 1.0 9.8 58.1 1.3 14.8 CLCN1 "ClC-1, CLC1" ENSG00000188037 "Chloride voltage-gated channel 1" P35523 7 143316111-143352083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 65.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 149.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "HSkMC: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (5.16e-2)" "unprognostic (4.99e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (9.53e-2)" "unprognostic (8.53e-2)" "unprognostic (1.42e-1)" "unprognostic (2.56e-4)" "unprognostic (8.71e-3)" "unprognostic (2.35e-1)" "unprognostic (2.90e-3)" "unprognostic (3.12e-1)" "unprognostic (2.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.47e-1)" "unprognostic (3.55e-3)" "unprognostic (3.57e-2)" 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 65.9 0.0 1.0 0.0 0.0 0.1 0.2 1.0 0.0 0.2 0.0 15.9 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.1 0.8 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 32.9 0.0 0.2 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.8 149.6 0.0 0.7 0.0 1.0 0.6 0.0 0.0 0.0 0.7 5.7 15.0 0.0 0.0 0.2 0.4 0.1 0.3 0.0 0.0 1.4 0.3 0.1 2.2 0.7 0.1 0.0 0.1 0.1 0.2 2.1 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 222.1;Granulosa cells: 140.8;Hofbauer cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" 49.3 16.6 15.5 25.0 14.3 20.0 32.8 15.6 28.1 40.2 9.5 16.8 7.1 30.4 16.6 10.4 25.5 32.7 26.2 15.6 18.0 19.7 10.7 35.4 32.3 24.9 15.8 38.9 7.9 29.4 10.1 44.4 19.3 23.4 12.1 3.0 17.4 16.7 6.4 22.2 18.8 27.7 17.0 36.1 11.9 59.7 19.1 35.5 16.1 13.0 20.9 34.3 26.7 20.4 6.7 33.8 93.4 66.2 68.4 42.6 59.2 17.5 78.6 34.4 34.0 18.6 21.0 0.2 47.7 49.0 59.7 7.8 63.7 57.4 27.3 34.6 23.2 21.5 4.4 53.5 92.2 65.8 77.4 85.5 4.5 36.6 7.7 141.3 78.9 59.5 34.6 0.7 42.8 7.8 53.1 108.9 45.0 0.5 31.8 164.7 65.6 3.3 16.4 0.8 9.9 33.9 8.5 0.3 58.5 59.9 0.7 59.3 54.0 48.7 58.8 12.0 21.1 4.4 0.7 21.8 30.5 50.0 53.7 7.9 14.2 9.9 9.2 13.9 12.9 2.6 10.3 10.5 12.3 0.9 8.0 9.8 8.0 8.6 8.9 24.9 15.7 5.8 15.5 14.3 15.6 28.1 15.6 18.0 24.9 15.8 19.3 17.0 19.1 20.4 38.0 0.0 7.1 0.3 12.9 14.7 33.5 10.0 6.8 0.5 12.3 25.7 2.0 4.3 6.4 5.5 0.0 10.7 101.2 0.4 0.0 28.1 2.8 4.9 56.0 50.4 12.5 12.8 0.6 6.4 222.1 62.6 2.6 6.2 91.3 140.8 44.3 1.3 119.8 0.0 0.3 0.7 8.2 74.7 77.9 9.4 39.4 78.0 28.4 10.3 61.5 10.0 82.4 8.0 0.2 41.0 0.1 24.5 5.7 40.8 0.1 4.4 3.1 0.8 6.6 26.3 36.1 4.9 8.1 1.1 8.7 9.4 68.9 10.5 0.2 21.6 CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" 40.3 26.2 11.6 69.0 11.4 97.3 54.4 11.7 13.5 50.4 24.8 47.7 26.7 46.3 41.0 40.3 176.6 50.3 18.5 10.8 13.4 40.0 132.4 54.3 53.9 14.5 12.5 18.6 23.5 41.6 9.2 70.1 14.3 48.6 58.4 13.0 33.2 39.9 5.0 49.4 29.5 41.6 14.5 55.4 46.9 40.4 13.5 47.8 61.7 13.6 78.3 79.0 18.9 14.7 107.4 34.2 66.5 50.1 112.1 111.0 292.4 77.5 110.4 79.7 91.5 36.6 174.4 63.5 86.1 104.6 53.8 67.6 47.0 128.9 108.2 285.4 57.3 80.4 22.8 54.5 79.6 135.3 153.0 110.5 81.3 92.0 68.6 128.2 130.3 60.9 39.8 116.0 103.0 33.4 81.9 70.0 59.3 88.6 50.0 68.6 51.7 49.9 111.1 147.9 15.3 44.3 70.5 39.5 76.1 66.9 58.3 133.5 117.8 88.0 57.9 86.7 94.1 59.6 63.9 58.6 61.4 116.8 112.1 176.8 84.4 208.0 29.1 133.4 32.8 54.4 38.1 28.3 72.7 42.2 22.0 24.7 313.4 65.1 210.2 38.6 46.3 108.6 11.6 11.4 11.7 13.5 10.8 13.4 14.5 12.5 14.3 14.5 13.5 14.7 57.0 35.3 49.9 12.4 243.7 96.0 82.4 159.3 55.2 13.9 233.0 57.5 5.8 60.1 112.0 95.6 12.5 253.6 122.5 88.0 33.2 113.8 12.3 129.1 68.3 70.7 132.1 41.2 14.2 83.0 101.7 74.9 63.2 180.9 126.8 186.5 124.9 305.2 156.5 50.5 19.2 117.6 118.0 310.1 815.8 8.4 39.4 326.0 81.8 30.0 425.8 130.1 71.1 18.1 9.4 136.7 46.1 42.9 104.7 147.1 23.8 63.4 183.0 17.3 39.5 32.9 74.3 36.1 20.2 89.7 126.6 261.7 120.9 50.3 64.6 110.3 CMTM8 CKLFSF8 ENSG00000170293 "CKLF like MARVEL transmembrane domain containing 8" Q8IZV2 3 32238679-32370321 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 47.7" "Cell type enhanced" "Detected in many" "Adipocytes: 94.7;Cytotrophoblasts: 107.6;Granulosa cells: 129.9;Syncytiotrophoblasts: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "BEWO: 208.4;SK-BR-3: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055077, HPA073258" Approved Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA055077: AB_2682691, HPA073258: AB_2686591" "unprognostic (9.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-1)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (9.46e-2)" "unprognostic (5.67e-2)" "unprognostic (8.85e-2)" "unprognostic (1.29e-1)" "unprognostic (7.59e-2)" "unprognostic (2.56e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" 14.8 12.9 6.0 3.3 5.8 1.2 15.5 4.9 6.7 5.9 5.9 7.0 7.3 4.4 17.4 3.5 8.4 3.4 13.6 5.5 5.0 10.2 41.2 17.9 3.9 6.2 5.4 1.4 47.7 12.0 3.6 17.4 6.3 11.7 7.4 1.1 19.7 6.0 4.7 9.2 6.2 2.5 5.5 1.3 14.9 1.0 7.0 9.5 13.6 5.1 4.1 4.8 3.7 4.9 10.6 10.8 2.1 13.5 9.5 14.7 208.4 0.1 0.3 1.1 1.2 15.0 14.9 0.0 21.8 0.0 0.0 5.8 17.2 3.5 0.9 0.0 31.5 6.8 2.1 25.2 0.6 2.8 5.3 28.8 10.8 1.5 10.4 5.2 8.4 11.2 0.1 0.0 10.7 7.8 8.9 1.0 4.4 16.4 9.9 12.4 2.5 2.1 13.1 12.1 3.7 3.0 1.7 59.3 5.8 2.5 17.0 1.4 7.6 0.0 15.5 0.0 3.2 0.5 0.4 0.1 0.0 4.8 3.7 0.0 0.0 1.6 0.1 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 6.0 5.8 4.9 6.7 5.5 5.0 6.2 5.4 6.3 5.5 7.0 4.9 94.7 38.5 36.3 1.0 2.8 11.6 35.2 4.6 18.8 0.1 75.4 45.6 2.2 17.2 16.1 0.0 0.0 107.6 2.3 13.7 11.7 18.1 13.0 22.1 5.6 51.9 22.2 5.7 2.2 37.0 67.5 17.7 32.1 29.2 0.0 129.9 54.7 79.5 9.8 0.0 41.6 40.7 16.2 5.3 15.0 2.4 2.5 3.6 5.4 36.5 1.2 35.6 0.0 17.6 1.0 25.8 17.7 1.2 1.4 64.9 21.3 24.3 9.9 2.7 0.0 2.2 12.3 3.5 3.7 12.1 6.5 116.2 18.6 10.9 21.0 49.7 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COLCA2 "C11orf93, CASC13" ENSG00000214290 "Colorectal cancer associated 2" A8K830 11 111298555-111308735 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.9;Cholangiocytes: 24.3;Early spermatids: 73.2;Ionocytes: 38.7;Late spermatids: 67.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 11.7;OE19: 41.4;RT4: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.73e-3)" "unprognostic (5.15e-2)" "unprognostic (6.97e-3)" "unprognostic (1.30e-3)" "unprognostic (1.15e-1)" "unprognostic (9.04e-2)" "unprognostic (1.13e-3)" "unprognostic (3.28e-2)" "unprognostic (6.03e-3)" "unprognostic (3.54e-2)" "unprognostic (3.34e-2)" "unprognostic (1.90e-1)" "prognostic favorable (8.97e-6)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.05e-2)" "unprognostic (2.46e-1)" 3.6 2.9 9.2 1.9 10.0 0.1 4.5 9.1 11.1 6.0 8.7 10.4 10.8 8.6 27.2 8.4 19.5 9.9 1.8 9.4 8.7 14.8 2.6 4.2 4.7 9.1 10.9 12.3 8.4 19.0 2.9 2.6 8.8 9.7 11.1 0.2 17.8 15.9 2.1 1.7 8.5 6.5 8.4 0.7 20.1 11.2 9.8 3.3 10.4 3.0 4.7 10.6 7.9 8.9 0.0 3.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 3.1 1.9 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 11.7 0.1 0.0 0.0 0.2 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.6 41.4 0.0 0.7 0.0 0.0 0.0 10.6 1.9 0.5 0.4 4.2 0.0 1.0 5.6 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 10.0 9.1 11.1 9.4 8.7 9.1 10.9 8.8 8.4 9.8 8.9 0.3 0.0 0.5 13.1 1.6 0.4 9.7 25.9 0.6 0.0 0.1 3.9 0.6 24.3 14.8 7.3 0.0 0.0 0.1 3.6 11.7 7.6 73.2 7.9 7.0 0.2 1.8 0.0 2.3 16.7 0.0 5.3 7.7 1.4 1.3 0.9 0.0 0.9 0.0 0.0 2.7 13.1 38.7 0.0 0.7 67.5 8.4 0.4 1.8 1.9 0.0 0.0 0.0 0.5 0.2 5.6 3.3 5.7 1.0 2.1 5.6 3.5 23.5 0.0 0.0 0.9 2.0 1.1 1.4 4.1 0.1 0.0 0.2 0.3 5.7 5.6 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COQ10A FLJ32452 ENSG00000135469 "Coenzyme Q10A" Q96MF6 12 56266890-56270966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 166.3;skeletal muscle: 280.7;tongue: 387.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068931 Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 24: NB-4 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Endoplasmic reticulum, Golgi apparatus" "HPA068931: AB_2686061" "unprognostic (4.55e-2)" "unprognostic (4.88e-3)" "prognostic unfavorable (5.46e-4)" "unprognostic (8.99e-3)" "unprognostic (2.77e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-1)" "unprognostic (2.86e-3)" "unprognostic (6.09e-2)" "unprognostic (8.57e-2)" "prognostic favorable (2.06e-4)" "unprognostic (5.03e-2)" "prognostic favorable (3.44e-4)" "unprognostic (1.67e-1)" "unprognostic (8.07e-2)" "unprognostic (7.20e-2)" "unprognostic (1.15e-1)" 7.0 33.3 16.3 3.5 16.9 4.6 7.2 17.7 19.7 9.1 21.1 9.5 3.2 10.0 16.2 9.0 10.8 6.3 166.3 16.2 17.6 17.1 37.0 6.7 7.8 16.5 18.3 10.2 18.0 15.7 25.4 2.7 17.2 11.9 5.0 26.0 12.6 9.8 280.7 5.0 9.7 7.2 16.4 12.2 8.8 6.8 18.6 7.9 10.3 387.5 8.9 8.5 6.8 15.8 3.7 15.2 14.4 9.4 8.1 8.0 6.0 5.2 12.5 18.3 18.2 11.9 5.6 21.5 11.3 13.3 5.1 3.5 16.8 3.0 10.9 3.2 17.0 10.2 14.1 12.4 11.0 8.1 5.9 8.4 4.9 13.6 5.3 11.4 9.8 14.9 6.8 8.8 17.1 5.1 11.7 29.1 12.0 2.7 8.7 24.2 15.6 14.5 10.1 2.2 20.5 22.0 18.1 3.8 5.8 10.6 5.8 8.9 6.9 3.4 10.0 9.5 5.3 18.1 20.4 10.8 10.2 7.6 2.6 14.1 1.1 1.1 7.4 1.0 7.4 12.7 7.0 7.8 1.7 6.8 8.3 8.1 0.4 5.8 0.9 6.9 5.1 3.9 16.3 16.9 17.7 19.7 16.2 17.6 16.5 18.3 17.2 16.4 18.6 15.8 8.1 3.2 7.2 12.4 20.8 13.4 13.0 2.3 15.4 17.9 8.4 12.7 120.5 7.2 3.2 11.0 16.7 5.8 32.0 2.0 52.8 2.8 0.2 13.7 6.3 9.6 16.2 4.2 3.9 4.6 6.8 10.9 6.6 5.1 4.5 8.2 3.6 15.2 5.2 32.0 6.2 3.4 4.1 2.5 12.1 1.7 8.4 4.5 12.4 3.7 2.5 26.5 13.4 4.5 2.3 2.7 2.5 17.0 18.6 4.4 3.1 18.1 11.0 32.3 39.5 22.1 14.0 4.0 22.2 4.9 10.5 3.0 19.5 10.4 4.4 5.9 CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 568.8;lymphoid tissue: 583.8" "Cell type enhanced" "Detected in many" "B-cells: 523.9;dendritic cells: 588.7;Hofbauer cells: 494.4;Kupffer cells: 395.8;Macrophages: 342.7;monocytes: 583.7;NK-cells: 968.1;T-cells: 663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 924.0;HL-60: 645.7;HMC-1: 1086.7;JURKAT: 603.0;MOLT-4: 632.5;NB-4: 771.8;RPMI-8226: 980.9;U-698: 618.2;U-937: 829.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 45000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB046473: AB_10602363, HPA051132: AB_2681355" "unprognostic (4.17e-3)" "unprognostic (3.64e-3)" "unprognostic (3.86e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.41e-1)" "prognostic favorable (4.42e-4)" "unprognostic (1.99e-2)" "unprognostic (8.27e-3)" "unprognostic (8.26e-3)" "unprognostic (4.30e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (2.55e-1)" "unprognostic (2.37e-2)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" 29.1 20.8 34.4 306.4 37.1 568.8 11.2 24.9 52.0 10.6 23.6 26.8 44.3 10.0 3.1 22.5 17.9 45.0 11.3 36.9 31.9 11.5 13.1 49.5 583.8 37.6 32.0 6.4 8.4 4.3 9.3 18.4 32.2 11.4 15.3 0.9 32.9 7.3 6.7 17.6 111.0 22.2 35.8 321.4 49.0 4.8 33.9 257.6 12.7 8.8 309.1 57.6 10.4 50.0 3.1 3.6 10.9 21.5 0.1 0.1 6.1 2.6 0.7 5.4 3.0 0.7 6.9 924.0 6.1 0.9 1.5 4.4 5.2 10.8 1.3 302.3 2.5 97.9 0.5 15.0 1.7 645.7 1086.7 2.8 0.0 4.3 0.5 0.4 2.0 603.0 1.5 467.6 3.4 80.7 632.5 771.8 4.0 3.1 6.4 340.0 17.5 980.9 1.3 5.1 17.3 13.0 2.2 110.7 2.0 0.2 1.9 373.0 1.6 4.0 9.0 2.7 3.1 348.5 497.7 618.2 3.0 829.6 6.3 797.2 773.6 2671.1 637.5 859.7 597.8 505.5 567.3 625.6 843.2 512.0 537.1 566.2 1318.9 531.0 898.0 482.1 858.7 1647.2 34.4 37.1 24.9 52.0 36.9 31.9 37.6 32.0 32.2 35.8 33.9 50.0 6.3 22.4 32.5 0.3 523.9 11.3 1.2 3.2 2.2 1.2 4.7 5.5 1.5 17.2 6.0 1.8 0.0 4.6 588.7 2.3 0.0 3.5 0.5 1.1 2.0 12.3 6.0 60.2 3.3 0.9 17.4 9.5 18.8 1.3 83.7 0.6 21.8 4.8 494.4 0.0 1.7 2.2 6.1 395.8 197.9 1.2 0.6 342.7 32.0 4.7 583.7 0.8 968.1 1.5 0.4 11.1 47.5 0.0 201.4 0.8 1.0 4.8 3.5 0.9 6.6 2.9 5.1 0.1 0.9 2.4 9.1 4.9 663.0 2.7 3.3 0.9 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 26 "granulocytes: 4422.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cell line enriched" "Detected in some" 45 "HEL: 303.3" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 18.2 2.6 0.0 19.9 0.4 25.7 20.9 0.0 0.0 59.4 0.3 39.2 27.3 26.1 19.3 41.1 6.6 112.0 6.2 0.0 0.0 3.3 2.7 86.3 11.2 0.0 0.0 0.9 21.0 2.8 0.9 1.7 0.0 18.5 56.6 0.0 12.1 15.1 1.6 17.7 45.9 25.7 0.0 1.1 45.3 3.8 0.0 14.9 0.9 10.2 15.1 54.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 303.3 0.0 0.0 0.2 0.2 6.7 0.2 0.0 0.1 0.3 0.5 3.8 0.0 0.1 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1115.4 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 163.9 0.0 0.5 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 16.0 0.0 1.6 0.0 3.5 0.5 0.0 4422.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 5.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 6.7 0.3 0.0 0.0 8.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 41.7 0.0 0.0 0.3 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CRMP1 "DPYSL1, DRP-1" ENSG00000072832 "Collapsin response mediator protein 1" Q14194 4 5748084-5893086 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.7;pituitary gland: 67.3;retina: 57.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 148.9;Excitatory neurons: 40.8;Horizontal cells: 210.3;Inhibitory neurons: 44.5;Muller glia cells: 78.4" "Cancer enhanced" "Detected in all" "glioma: 37.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 81.0;HAP1: 117.2;NTERA-2: 84.3;REH: 229.4;RH-30: 129.6;SCLC-21H: 167.2;SH-SY5Y: 105.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035640, CAB037313" Approved Supported Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Centrosome Cytosol "CAB037313: AB_1078571, HPA035640: AB_10670838" "unprognostic (1.56e-1)" "unprognostic (7.22e-2)" "unprognostic (5.14e-2)" "unprognostic (8.08e-3)" "unprognostic (2.80e-1)" "unprognostic (2.22e-1)" "unprognostic (1.84e-2)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (9.71e-2)" "prognostic favorable (4.54e-4)" "unprognostic (2.26e-1)" "unprognostic (8.52e-3)" "unprognostic (1.21e-2)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.60e-3)" 1.8 9.8 53.0 2.7 55.9 0.1 0.9 45.0 58.0 9.6 10.7 4.4 1.3 21.9 0.1 2.7 4.9 5.1 2.8 59.7 57.9 2.1 0.3 5.7 1.9 31.0 35.2 7.9 5.7 0.7 67.3 5.4 41.0 3.2 1.6 57.6 2.7 3.1 0.5 3.7 2.9 14.5 30.8 1.1 3.7 3.0 47.1 1.2 2.4 1.1 1.0 2.6 2.9 38.2 1.3 2.7 81.0 2.8 0.1 0.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 27.2 1.9 117.2 0.0 0.0 2.2 0.9 0.0 4.0 0.6 1.4 0.1 0.7 1.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.3 1.3 0.0 0.4 0.0 84.3 0.0 2.6 229.4 129.6 20.2 0.0 0.2 167.2 105.8 0.0 0.6 1.4 54.2 0.8 0.1 6.8 3.8 27.3 2.3 2.6 14.8 2.2 0.1 9.8 0.9 69.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 55.9 45.0 58.0 59.7 57.9 31.0 35.2 41.0 30.8 47.1 38.2 1.0 0.0 1.1 23.8 0.0 0.4 0.0 1.5 0.0 148.9 0.0 0.0 1.5 0.0 0.0 0.0 18.8 0.1 0.0 0.0 0.0 0.1 2.2 0.4 13.6 6.3 2.4 1.3 40.8 0.0 0.2 3.5 3.1 0.5 0.0 2.4 0.0 0.0 0.5 210.3 44.5 0.0 0.0 0.0 0.0 5.5 0.6 0.2 1.8 6.5 0.0 78.4 0.0 33.2 2.9 0.4 0.0 0.4 0.0 0.4 0.0 0.0 0.0 22.8 6.6 0.4 6.2 1.0 12.4 1.1 0.1 0.3 0.2 1.5 0.0 0.1 CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 75.0;Distal tubular cells: 19.6;Granulosa cells: 30.7;Muller glia cells: 51.7;Proximal tubular cells: 42.5;Sertoli cells: 72.3;Smooth muscle cells: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 12.4;U-2 OS: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" 6.8 143.8 29.4 1.6 21.8 0.1 3.2 64.5 32.1 69.9 4.1 16.5 0.8 83.5 1.4 3.2 24.1 2.3 288.2 30.5 35.3 40.4 2.6 11.5 0.2 44.4 41.0 133.6 51.1 0.0 20.5 0.4 36.9 26.2 0.5 5.2 1.0 10.4 2.7 2.1 3.2 10.9 26.1 1.1 4.5 31.3 44.9 0.0 2.5 2.7 0.0 27.4 29.0 22.7 0.0 0.2 1.5 0.2 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.9 0.0 0.0 0.5 4.7 0.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 12.4 1.5 3.5 0.0 0.0 1.9 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.1 1.1 0.2 0.0 0.1 0.1 1.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.1 41.8 0.3 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 29.4 21.8 64.5 32.1 30.5 35.3 44.4 41.0 36.9 26.1 44.9 22.7 0.1 0.0 0.0 4.6 0.5 0.3 0.2 0.3 0.6 9.9 0.1 0.6 75.0 0.0 0.0 7.3 2.1 0.1 0.0 0.0 19.6 0.3 1.5 0.2 6.0 0.9 0.0 0.0 6.8 10.4 0.1 5.1 0.0 0.1 0.0 30.7 0.4 0.2 0.2 6.7 11.0 0.0 0.0 0.0 0.0 5.1 5.3 0.3 1.8 0.0 0.0 51.7 0.0 1.0 0.6 2.4 0.0 2.6 0.0 0.2 0.0 42.5 0.7 3.2 72.3 0.4 19.9 2.1 0.3 0.0 0.1 0.3 0.2 0.3 0.0 0.0 CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.5;Extravillous trophoblasts: 124.6;Langerhans cells: 365.1;Macrophages: 114.5;monocytes: 575.2;Syncytiotrophoblasts: 312.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Group enriched" "Detected in some" 7 "BEWO: 194.0;HMC-1: 58.3;SK-MEL-30: 142.0" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" 10.0 5.5 4.2 25.4 4.4 21.7 6.8 5.2 4.8 5.1 5.4 5.8 5.8 2.5 1.7 5.3 4.1 12.6 2.5 4.0 5.4 2.3 4.6 14.2 20.9 8.5 6.6 1.8 3.3 3.1 1.4 64.4 8.3 2.5 7.4 0.7 3.0 3.0 0.6 4.0 6.6 7.1 7.2 14.9 5.0 1.1 9.0 9.4 1.6 2.0 23.5 12.7 1.5 11.9 0.3 11.5 0.5 0.0 0.0 0.0 194.0 0.3 0.5 0.4 0.1 4.2 1.0 0.2 12.6 0.0 10.3 0.2 0.1 0.0 0.0 3.9 0.1 0.2 8.0 0.1 0.0 4.6 58.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.2 0.4 18.8 1.6 1.8 0.4 0.2 0.5 0.3 0.0 0.5 0.1 0.3 3.7 0.1 142.0 15.1 9.4 16.8 0.0 0.2 5.5 0.1 0.0 0.1 0.1 0.6 0.0 18.5 0.1 17.4 161.1 200.3 0.4 94.9 1.0 2.3 0.3 0.3 170.7 0.6 0.4 0.3 320.2 7.3 48.7 164.0 1.1 65.5 4.2 4.4 5.2 4.8 4.0 5.4 8.5 6.6 8.3 7.2 9.0 11.9 1.2 0.0 7.3 1.3 5.5 7.8 0.9 0.1 0.6 0.6 6.3 2.5 1.2 2.8 3.6 1.8 0.0 248.5 38.3 0.0 0.0 0.3 0.6 7.8 1.2 5.3 0.0 1.3 1.4 1.8 124.6 3.4 0.0 14.7 10.1 0.5 0.7 0.1 75.5 0.0 1.7 0.0 2.0 74.8 365.1 0.3 0.9 114.5 8.8 66.5 575.2 0.3 0.0 1.5 0.9 0.2 0.0 0.4 1.0 0.5 0.0 0.1 2.7 1.5 6.6 1.8 1.4 0.2 0.4 0.0 5.3 312.5 3.3 0.1 0.0 2.5 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 87.1 52.8 81.1 41.2 82.6 51.6 88.3 80.8 95.1 93.6 66.0 73.0 41.4 82.7 52.5 69.0 83.3 48.7 80.9 82.9 73.7 70.2 37.4 92.2 40.3 78.9 78.6 109.5 64.9 74.1 85.1 71.2 79.5 80.3 35.5 47.3 71.6 44.9 60.5 94.8 50.9 45.3 70.2 63.6 58.0 29.5 83.2 33.3 64.4 47.2 37.8 65.7 88.4 93.9 101.5 57.4 121.6 114.7 61.5 88.3 92.1 126.9 168.6 116.7 114.3 63.9 76.7 74.2 53.0 120.7 70.7 77.9 96.1 177.9 79.2 123.0 215.2 23.9 181.2 47.4 123.7 48.3 61.9 90.2 143.8 171.7 220.3 141.0 121.1 60.6 50.9 155.0 110.8 68.4 71.1 60.9 87.2 67.3 69.1 130.8 90.1 123.4 99.0 92.4 181.6 69.3 102.9 109.3 124.7 68.0 59.5 73.0 134.3 94.0 111.3 58.7 102.1 61.2 105.2 104.5 151.0 56.9 176.3 4.8 1.6 3.6 3.0 0.8 3.8 2.1 3.4 3.0 1.8 3.1 1.9 2.5 3.8 5.7 0.5 15.9 1.6 1.2 81.1 82.6 80.8 95.1 82.9 73.7 78.9 78.6 79.5 70.2 83.2 93.9 73.4 38.5 21.7 0.0 32.3 78.6 158.8 89.1 68.9 132.6 53.7 42.4 49.8 34.3 73.9 23.9 60.5 35.2 42.3 28.4 7.9 30.8 46.0 94.3 72.5 76.4 62.8 12.6 0.0 41.8 49.2 60.8 39.8 126.5 3.8 46.6 45.0 21.3 23.1 72.3 0.0 46.0 46.8 17.6 54.1 69.1 85.4 21.8 60.5 0.0 13.3 117.9 28.8 0.0 0.0 57.5 33.1 66.2 83.5 160.5 9.0 6.5 62.8 60.7 72.3 85.7 98.0 8.0 20.0 50.3 104.7 125.5 26.0 34.9 37.6 280.8 CSRNP3 "FAM130A2, FLJ32093, PPP1R73, TAIP-2" ENSG00000178662 "Cysteine and serine rich nuclear protein 3" Q8WYN3 2 165469647-165689407 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 358.3;Inhibitory neurons: 315.3;Oligodendrocyte precursor cells: 344.8;Oligodendrocytes: 95.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.8;PC-3: 2.4;SCLC-21H: 7.1;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017905 Approved Uncertain "Nucleoplasm,Nucleoli rim" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli rim" Nucleoplasm "HPA017905: AB_1857757" "unprognostic (2.85e-1)" "unprognostic (1.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.61e-1)" "unprognostic (8.87e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-3)" "unprognostic (7.41e-2)" "unprognostic (5.36e-2)" "unprognostic (3.17e-1)" "unprognostic (1.08e-2)" 0.9 2.3 9.4 0.4 9.3 0.0 3.2 0.0 14.4 2.3 7.0 0.8 0.7 2.7 0.8 0.7 0.9 0.9 1.4 10.6 10.5 1.5 0.6 0.4 0.2 0.0 0.7 3.4 3.7 1.1 3.4 0.2 0.0 1.5 0.9 6.4 2.2 2.1 0.1 0.7 0.6 2.5 0.0 0.8 0.7 0.6 8.6 0.5 2.3 0.7 0.2 0.6 1.0 6.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.4 0.0 0.3 0.1 0.5 0.0 0.2 0.0 0.7 0.4 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.0 0.6 0.5 0.0 7.1 5.8 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.3 0.0 14.4 10.6 10.5 0.0 0.7 0.0 0.0 8.6 6.5 2.5 3.2 5.1 81.6 0.2 5.2 4.0 2.3 6.8 55.7 16.2 13.5 8.7 5.7 1.6 11.0 70.9 0.3 0.0 0.7 3.9 2.7 2.9 2.3 9.6 3.6 7.7 0.0 358.3 2.3 0.1 8.2 2.0 2.3 0.0 47.9 1.4 3.6 2.6 11.8 315.3 4.7 4.1 0.3 1.6 1.7 7.5 0.4 7.2 7.5 0.0 19.6 0.0 344.8 95.4 0.9 1.9 8.2 0.0 0.6 1.7 7.2 0.5 20.4 6.6 4.4 23.0 0.6 1.6 6.3 4.5 0.3 0.2 13.2 2.6 2.0 CSRP3 "CLP, CMD1M, MLP" ENSG00000129170 "Cysteine and glycine rich protein 3" P50461 11 19182030-19210571 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Actin-binding, Developmental protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2613.3;skeletal muscle: 1649.3;tongue: 579.0" "Cell type enriched" "Detected in some" 35 "Cardiomyocytes: 3433.6" "Cancer enriched" "Detected in some" 6 "head and neck cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA042581 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 250000 "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Nucleoplasm "HPA042581: AB_2678061" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.55e-2)" "unprognostic (4.72e-2)" "unprognostic (5.99e-2)" "unprognostic (1.08e-1)" 0.3 0.2 0.3 0.0 0.1 0.1 2.8 0.5 0.3 0.0 0.0 0.2 0.0 0.1 0.0 39.6 0.0 0.5 2613.3 0.1 0.2 0.2 0.2 1.2 1.2 0.2 0.1 0.5 2.6 0.0 0.1 0.1 0.2 32.8 0.0 0.0 24.8 0.0 1649.3 0.4 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.7 579.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3433.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 28.8 0.0 0.0 0.3 6.0 0.0 79.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 95.5 32.7 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1095.6" "Group enriched" "Detected in many" 9 "dendritic cells: 1094.4;Langerhans cells: 541.7;monocytes: 659.7;NK-cells: 1385.2;T-cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1287.0" "Group enriched" "Detected in all" 27 "granulocytes: 342.2;NK-cells: 655.3;T-cells: 1287.0" "Cell line enhanced" "Detected in some" "HL-60: 77.8;HMC-1: 204.6;NB-4: 212.1;U-937: 380.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" NA NA 26000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" 18.0 3.6 1.3 24.2 1.6 1095.6 5.7 2.8 5.1 4.5 1.7 5.7 5.9 4.6 4.8 5.4 10.4 17.7 5.6 1.5 1.4 5.4 12.7 49.3 73.4 2.4 1.4 2.5 3.9 1.0 2.2 4.4 2.0 4.3 5.1 0.2 6.6 2.0 1.9 4.5 13.9 5.0 1.6 148.1 8.7 1.7 1.6 17.3 5.6 4.4 16.4 19.2 5.2 1.4 0.3 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.3 1.7 0.0 0.4 0.0 77.8 204.6 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 2.8 0.0 0.2 2.0 212.1 0.1 0.0 0.2 0.5 7.7 0.1 0.0 0.1 0.3 0.2 0.0 0.1 1.0 0.1 0.0 13.3 0.2 0.1 0.8 0.2 0.5 0.1 0.1 0.2 0.1 380.4 0.1 74.3 3.0 10.4 1287.0 3.4 720.2 3.7 186.8 904.7 28.4 3.9 38.8 531.2 342.2 655.3 3.5 7.2 123.0 600.8 1.3 1.6 2.8 5.1 1.5 1.4 2.4 1.4 2.0 1.6 1.6 1.4 8.1 9.6 14.1 0.0 14.5 22.8 0.3 0.0 0.0 0.0 2.5 2.4 1.4 4.3 0.6 0.0 0.0 0.2 1094.4 0.3 0.0 1.3 0.0 1.3 0.7 3.2 0.0 46.7 0.0 3.7 0.1 5.2 11.2 1.2 60.0 0.0 11.0 3.8 1.4 0.0 0.0 0.1 0.0 16.2 541.7 0.0 0.0 61.9 24.9 1.9 659.7 0.0 1385.2 0.0 0.1 0.2 0.1 0.0 90.9 0.1 0.4 2.3 2.2 0.0 0.0 2.2 3.6 0.0 0.2 0.5 23.9 1.1 544.5 0.0 0.6 0.6 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 CTNNA3 "MGC26194, VR22" ENSG00000183230 "Catenin alpha 3" Q9UI47 10 65912523-67696195 "Disease related genes, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 176.3" "Cell type enriched" "Detected in some" 14 "Oligodendrocytes: 4054.6" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;Karpas-707: 1.5;NTERA-2: 1.7;RPMI-8226: 2.4;SCLC-21H: 1.5;U-266/70: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061818 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA061818: AB_2684618" "unprognostic (2.19e-1)" "unprognostic (1.57e-1)" "unprognostic (8.64e-4)" "unprognostic (8.13e-3)" "unprognostic (6.43e-3)" "unprognostic (9.90e-2)" "unprognostic (2.60e-4)" "unprognostic (8.27e-2)" "unprognostic (5.10e-2)" "unprognostic (2.55e-1)" "unprognostic (9.09e-3)" "unprognostic (1.15e-1)" "unprognostic (2.67e-3)" "unprognostic (7.93e-5)" "unprognostic (6.43e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" 0.7 0.5 31.8 0.6 96.9 0.1 0.5 49.3 49.7 1.4 0.0 2.0 0.3 1.3 0.1 1.4 0.7 0.6 18.7 30.3 51.6 0.5 8.5 0.1 0.2 90.9 66.8 1.7 0.1 0.2 0.2 0.4 95.3 0.4 0.6 0.4 0.3 0.2 12.0 0.2 0.8 2.6 52.4 0.3 1.2 2.2 69.7 0.1 0.3 23.4 0.3 0.6 0.6 176.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.7 0.6 0.7 0.1 0.0 2.4 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.4 0.0 0.0 6.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.8 96.9 49.3 49.7 30.3 51.6 90.9 66.8 95.3 52.4 69.7 176.3 0.4 0.0 0.0 24.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 75.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 217.8 0.0 1.5 1.2 0.0 0.0 49.8 0.0 0.0 2.5 0.0 0.1 0.0 2.6 0.4 5.7 0.0 0.0 50.6 0.0 0.0 0.8 0.3 275.5 4.4 0.3 0.0 30.0 0.0 1.4 0.0 50.3 4054.6 0.0 0.1 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 9.3 4.0 1.6 0.0 0.1 0.0 0.1 4.6 0.1 0.0 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573518-24576250 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 154 "bone marrow: 5352.9" "Cell type enriched" "Detected in some" 16 "granulocytes: 534.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "THP-1: 8681.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" NA NA 330000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB000110: , HPA047737: AB_2680140" "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.91e-4)" 23.4 0.1 0.0 13.5 0.0 5352.9 25.4 0.0 0.0 16.6 0.0 25.5 5.8 9.6 10.2 22.1 2.7 25.9 3.7 0.0 0.0 2.3 3.6 11.6 6.5 0.0 0.0 0.5 3.5 1.5 1.0 2.9 0.0 3.7 25.5 0.0 11.5 4.8 1.8 28.0 18.1 7.7 0.0 16.9 4.9 3.2 0.0 26.0 0.8 7.6 6.0 34.8 4.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 303.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 3.6 41.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.2 0.0 3.6 0.0 0.0 8681.4 0.0 0.0 0.3 0.0 5.3 0.0 0.8 2.8 0.0 1287.5 0.1 0.0 6.0 0.0 1.1 1.0 0.0 0.0 0.9 3.4 5.4 0.0 0.0 1.7 7.3 5.0 0.0 6.5 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 33.3 0.0 0.2 6.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 534.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 11.1 9.1 0.0 1.5 5.4 0.0 1.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 1.3 0.3 1.7 0.0 4.0 0.0 5.1 0.0 0.4 0.0 CTXN3 ENSG00000205279 "Cortexin 3" Q4LDR2 5 127649044-127658630 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "kidney: 79.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 201.3" "Cancer enriched" "Detected in single" 8 "renal cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (7.32e-2)" "unprognostic (9.88e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (6.20e-3)" 0.0 0.0 3.1 0.0 4.2 0.0 0.0 1.9 10.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 4.8 79.8 0.0 0.1 0.0 8.3 11.8 0.0 0.0 0.2 5.3 0.0 10.2 0.5 0.0 0.2 0.2 0.0 12.9 0.0 0.0 0.0 2.6 0.0 0.0 0.1 5.3 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 4.2 1.9 10.2 5.1 4.8 8.3 11.8 10.2 2.6 5.3 3.6 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 23.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 201.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 140.4" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 257.7;Proximal tubular cells: 325.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.8;ASC TERT1: 3.0;SK-MEL-30: 2.8;WM-115: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" 0.7 0.8 0.8 0.4 0.9 0.4 0.8 0.8 0.7 1.2 1.3 0.5 0.2 0.7 3.1 0.2 2.1 0.3 0.6 0.8 0.8 140.4 0.1 0.6 0.8 2.5 1.7 2.5 0.5 0.6 2.2 2.6 2.4 1.1 0.2 3.0 0.7 0.4 0.3 0.8 28.0 0.4 1.7 0.9 0.4 2.0 1.0 1.7 3.8 0.5 0.7 0.4 0.7 0.6 0.0 0.0 1.5 14.8 0.5 3.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.6 1.5 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.1 0.0 0.1 1.6 0.1 0.2 0.3 0.1 0.5 0.0 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.9 0.8 0.7 0.8 0.8 2.5 1.7 2.4 1.7 1.0 0.6 3.2 0.0 1.5 23.8 3.7 0.5 0.4 0.2 0.6 2.9 0.6 0.6 1.7 0.0 3.2 5.5 2.1 0.0 3.3 0.1 13.7 0.0 37.3 3.1 2.2 5.7 0.0 0.0 8.4 0.2 0.0 2.3 0.0 2.2 0.0 2.2 1.4 0.0 0.1 0.0 9.0 3.7 0.0 0.3 0.4 31.8 2.8 3.1 7.2 7.5 0.1 6.5 1.0 9.0 5.5 0.1 5.0 1.2 1.6 0.4 257.7 325.0 3.5 4.0 0.0 19.0 1.6 1.1 0.9 0.1 0.9 0.1 2.9 1.2 1.2 0.2 CUTC CGI-32 ENSG00000119929 "CutC copper transporter" Q9NTM9 10 99702558-99756134 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 385.5;tongue: 204.2" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038619, HPA058231" Enhanced Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" Nucleoli "HPA038619: AB_10672649, HPA058231: " "unprognostic (1.25e-2)" "unprognostic (5.92e-2)" "unprognostic (2.70e-1)" "unprognostic (8.66e-2)" "unprognostic (7.39e-2)" "unprognostic (1.39e-1)" "unprognostic (3.55e-3)" "unprognostic (8.67e-2)" "unprognostic (5.36e-2)" "unprognostic (1.81e-1)" "unprognostic (5.87e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.81e-7)" "unprognostic (1.00e-1)" "unprognostic (3.42e-2)" "unprognostic (2.41e-1)" "unprognostic (3.97e-1)" 38.7 15.5 19.3 14.6 21.9 23.6 27.3 20.8 25.9 17.3 17.3 19.4 11.1 14.7 11.0 16.0 17.1 12.1 41.7 18.7 20.7 13.5 30.2 15.1 22.3 21.0 20.6 12.6 14.2 8.6 7.8 11.3 21.3 16.1 15.9 28.3 16.9 11.2 385.5 18.6 20.9 14.4 20.1 28.6 18.6 43.4 20.3 23.9 13.2 204.2 19.7 43.8 16.7 25.0 27.4 57.7 19.9 60.7 71.8 32.8 10.8 22.0 28.0 21.6 24.2 26.7 20.5 98.9 19.1 37.5 10.6 22.9 40.8 36.6 23.9 29.5 39.0 32.9 26.1 42.7 33.2 61.5 15.5 34.0 22.3 34.5 71.1 26.8 37.8 56.2 29.6 21.4 16.4 19.4 55.7 63.2 20.0 27.7 21.4 37.5 23.3 38.3 22.8 11.2 6.5 14.8 10.1 15.9 28.9 27.1 25.3 34.7 21.2 9.0 12.2 9.9 29.5 34.7 48.5 69.6 29.4 130.0 8.2 70.6 42.6 111.7 56.9 35.2 60.0 73.4 53.9 54.9 47.1 66.5 74.4 57.2 68.6 63.1 46.0 54.2 57.0 45.3 19.3 21.9 20.8 25.9 18.7 20.7 21.0 20.6 21.3 20.1 20.3 25.0 26.3 9.6 12.5 15.3 32.8 12.1 14.7 23.1 5.7 18.7 12.6 15.2 40.6 14.3 14.9 5.5 8.4 18.6 23.2 4.6 21.5 16.9 12.6 11.4 12.0 19.8 12.1 28.2 8.5 17.4 13.5 32.8 10.7 8.3 30.4 14.4 27.5 23.4 20.9 11.8 9.0 7.4 12.2 17.0 11.7 10.8 13.1 16.6 30.2 7.5 28.0 25.9 21.6 8.0 26.9 10.5 7.4 16.1 27.2 16.1 19.2 34.8 21.5 33.0 19.7 27.1 15.5 163.3 36.7 14.3 10.9 13.5 25.6 36.3 9.6 11.6 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "pons: 124.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 432.2;SK-BR-3: 209.2;T-47d: 168.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA014753: AB_1847364" "prognostic unfavorable (8.89e-5)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-5)" "unprognostic (1.81e-3)" "unprognostic (3.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.91e-2)" "unprognostic (8.97e-2)" "unprognostic (6.38e-2)" "unprognostic (8.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.89e-1)" 14.8 125.6 22.2 12.3 24.4 4.1 32.8 6.8 23.1 45.0 70.6 26.4 36.6 12.3 57.2 51.9 55.8 17.3 16.2 20.4 33.2 24.5 21.0 30.9 8.3 17.2 23.2 9.4 118.0 76.1 74.1 16.2 124.7 63.3 21.1 9.8 85.0 37.8 6.0 37.3 31.9 9.2 9.8 8.7 48.1 6.0 28.0 3.5 40.8 4.6 12.8 16.4 27.4 17.9 99.3 31.9 2.6 20.5 11.5 52.7 43.3 10.3 12.0 12.3 4.9 29.2 96.9 0.2 23.0 75.5 3.3 83.1 20.3 8.0 4.8 26.1 8.7 12.7 20.4 2.0 21.7 1.3 4.3 8.6 84.1 11.2 1.5 17.9 23.9 0.1 41.2 17.7 4.0 140.3 0.5 4.9 20.9 80.5 49.9 0.3 0.2 31.0 40.0 49.8 73.7 432.2 26.0 209.2 10.4 7.3 168.6 6.2 3.6 25.9 29.4 60.6 3.1 0.4 0.4 0.1 22.6 5.1 14.0 0.3 2.0 0.2 19.2 5.7 24.6 0.6 14.4 13.2 2.1 0.6 1.3 4.2 5.2 20.3 7.7 0.1 0.0 5.8 22.2 24.4 6.8 23.1 20.4 33.2 17.2 23.2 124.7 9.8 28.0 17.9 14.6 28.9 37.8 3.6 3.5 16.4 23.7 16.0 26.2 6.1 37.4 24.6 12.8 20.0 36.7 23.9 0.0 25.1 7.0 22.2 3.9 41.1 6.9 74.5 12.5 18.3 21.6 3.4 14.1 50.5 29.2 15.0 30.1 53.9 15.9 7.3 11.4 11.1 4.7 0.0 10.7 31.7 18.3 7.0 9.8 6.2 3.7 4.1 3.6 9.4 6.0 5.2 2.1 0.5 0.6 30.8 11.4 3.4 15.3 41.6 32.1 11.9 68.5 26.8 6.6 5.1 7.6 6.9 7.2 34.2 27.8 24.8 11.4 0.4 26.2 22.6 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DACT1 "DAPPER, DAPPER1, FRODO, HDPR1, THYEX3" ENSG00000165617 "Dishevelled binding antagonist of beta catenin 1" Q9NYF0 14 58633967-58648321 "Disease related genes, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 56.0;Late spermatids: 17.9;Peritubular cells: 27.8;Smooth muscle cells: 15.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 17.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 13.5;SuSa: 17.2;U-138 MG: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003016, HPA074619" Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA003016: AB_1078623, HPA074619: " "unprognostic (2.47e-2)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (3.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (4.79e-2)" "unprognostic (1.93e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" 8.6 7.9 5.2 4.1 4.2 1.5 6.5 17.4 3.3 12.0 0.6 6.3 5.9 7.6 5.8 2.9 5.9 24.9 8.0 3.6 2.5 5.5 2.7 9.3 4.1 1.6 3.2 24.4 2.3 8.0 3.8 12.1 2.0 11.8 6.7 2.0 3.5 13.1 2.4 2.7 3.9 8.9 2.0 7.2 6.9 9.8 2.4 3.6 10.7 4.4 2.3 14.0 6.6 3.4 0.0 0.0 4.0 0.1 4.5 5.0 0.1 2.3 2.9 2.4 2.1 0.3 0.2 0.0 0.1 6.9 4.0 3.6 11.5 0.0 1.3 2.7 2.4 0.0 0.1 0.0 8.2 0.0 1.3 5.9 0.3 9.0 0.0 9.0 0.1 0.8 0.0 0.0 1.6 0.0 0.9 0.1 3.8 0.2 0.9 4.9 5.6 0.0 0.0 0.0 0.1 0.0 6.5 0.0 13.5 17.2 0.0 0.4 0.0 31.7 10.8 0.5 8.5 4.4 1.8 0.0 3.4 1.4 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.2 4.2 17.4 3.3 3.6 2.5 1.6 3.2 2.0 2.0 2.4 3.4 1.1 0.0 0.0 0.3 1.0 0.8 1.2 0.0 1.2 0.4 0.3 1.5 3.9 7.2 0.0 1.8 0.0 0.2 0.2 0.3 0.0 1.7 56.0 0.4 9.3 1.4 0.0 0.0 2.7 2.3 0.8 11.7 2.0 0.3 0.0 2.3 4.2 0.0 1.2 0.0 4.0 1.0 0.0 2.9 2.1 17.9 12.2 0.6 1.8 6.5 0.0 4.5 0.0 1.5 0.8 3.1 0.0 27.8 0.6 0.4 0.0 1.0 0.0 0.5 0.0 2.9 15.7 12.6 8.6 0.3 1.3 0.1 0.5 3.6 0.5 0.4 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078445-150257438 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.0" "Group enriched" "Detected in many" 6 "Astrocytes: 501.1;Excitatory neurons: 189.8;Inhibitory neurons: 173.2;Oligodendrocyte precursor cells: 172.4" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 23.6;BJ: 11.8;BJ hTERT+: 24.9;fHDF/TERT166: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.25e-4)" "prognostic favorable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 1.7 2.8 45.8 0.9 42.0 0.5 1.4 34.6 43.6 2.0 7.7 5.6 1.4 2.7 2.0 1.5 1.9 2.5 12.2 59.0 41.2 2.3 0.6 2.1 0.4 41.2 46.6 2.9 2.2 0.6 8.3 1.5 38.4 2.7 2.0 18.4 0.8 2.0 1.2 1.0 2.2 4.7 46.6 1.2 2.3 2.8 42.7 0.2 2.6 1.4 0.3 2.6 1.3 46.8 1.2 4.2 23.6 3.7 0.0 1.1 0.4 11.8 24.9 3.5 0.9 0.1 0.0 0.0 0.4 11.0 3.6 0.1 3.5 0.0 4.4 5.1 2.1 0.0 7.0 0.0 5.0 0.7 0.7 0.6 0.0 2.2 0.2 2.2 1.2 0.6 0.0 0.1 2.5 0.2 0.4 0.0 0.5 0.3 1.6 0.0 2.8 1.0 0.1 1.0 9.2 9.1 4.7 3.4 1.0 2.0 0.0 0.1 2.1 3.3 1.3 2.2 1.3 1.1 0.0 0.1 3.1 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 45.8 42.0 34.6 43.6 59.0 41.2 41.2 46.6 38.4 46.6 42.7 46.8 10.7 0.0 0.0 501.1 0.6 0.5 0.1 0.0 0.6 26.2 2.8 2.2 10.5 1.5 0.7 3.7 16.7 0.0 0.0 0.8 0.0 0.4 0.1 0.4 4.6 7.6 3.0 0.0 189.8 0.7 0.0 3.4 1.1 0.5 4.5 5.7 7.5 0.0 1.6 35.3 173.2 0.3 0.0 0.6 3.4 0.3 1.8 0.7 5.4 43.1 0.2 31.2 0.0 172.4 37.6 0.1 0.4 3.8 0.3 0.6 0.0 0.4 0.1 9.6 13.1 5.6 9.2 0.1 2.0 0.1 0.6 0.3 0.9 6.6 1.4 0.2 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 96.5 17.2 26.6 12.0 24.7 10.8 81.2 24.2 44.7 131.5 26.1 72.2 4.4 94.4 8.7 39.0 80.5 44.0 63.2 23.9 33.5 67.1 32.1 62.3 20.6 31.8 28.2 67.7 16.5 17.5 26.0 18.3 28.1 65.2 7.7 5.8 58.2 27.0 13.4 67.7 38.9 11.9 32.0 49.4 35.4 13.4 27.4 9.6 65.1 4.5 7.8 61.0 91.0 30.9 2.0 20.1 0.7 28.5 17.0 26.6 3.8 0.0 10.6 10.9 7.3 40.4 6.7 0.4 24.4 26.5 0.9 2.4 0.5 9.7 1.9 0.0 14.2 1.9 7.8 22.4 18.2 0.3 1.5 18.8 1.2 12.2 0.9 3.7 33.3 14.1 0.4 11.1 4.8 63.0 1.5 27.5 4.1 4.3 12.2 0.2 0.9 10.5 21.6 0.5 1.5 5.7 0.0 4.7 27.4 2.9 37.7 7.8 0.1 16.9 24.7 11.2 0.0 4.1 12.8 3.3 11.3 5.9 4.3 141.3 15.4 135.0 14.8 37.4 5.8 49.7 4.0 5.3 26.8 39.6 2.7 3.4 27.8 29.2 44.9 93.9 4.1 11.4 26.6 24.7 24.2 44.7 23.9 33.5 31.8 28.2 28.1 32.0 27.4 30.9 102.3 28.9 14.7 10.4 76.8 66.9 88.7 49.6 56.3 4.5 132.8 96.0 39.5 62.9 36.9 82.8 29.2 15.5 84.4 386.3 178.1 148.2 83.1 62.6 94.2 101.2 150.0 20.4 0.3 32.3 37.3 154.1 33.1 75.0 113.3 121.7 94.9 31.9 223.2 0.0 0.3 71.5 109.9 139.7 301.2 23.6 180.5 95.7 103.2 14.0 64.2 120.9 40.2 4.5 2.7 85.1 299.5 153.1 24.5 95.2 61.5 165.8 50.5 25.7 105.2 122.7 153.0 4.1 12.5 35.8 59.2 18.1 41.1 21.3 104.6 67.0 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.3;Inhibitory neurons: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nuclear speckles" "HPA042586: AB_2678064" "unprognostic (8.79e-2)" "unprognostic (1.58e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (7.79e-3)" "unprognostic (3.99e-2)" "unprognostic (3.13e-2)" "unprognostic (5.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" 2.0 2.7 2.4 3.8 8.3 5.6 5.7 3.9 3.0 3.1 1.5 6.0 5.7 2.1 4.0 4.4 2.0 3.4 5.8 2.1 4.4 5.6 5.0 4.3 6.5 2.9 5.3 4.0 5.8 5.9 2.5 1.5 3.6 3.8 5.7 5.9 4.5 3.2 3.9 1.9 6.9 1.9 1.9 4.3 4.8 2.2 4.5 6.6 6.0 5.9 6.5 4.0 2.8 2.6 7.2 1.8 2.0 3.4 0.9 5.0 3.0 5.4 3.7 3.3 2.0 1.9 4.5 13.0 2.7 8.3 1.9 3.6 3.2 3.9 2.9 10.0 3.4 4.7 3.7 0.9 2.7 15.5 5.6 1.7 5.2 1.3 3.6 10.0 1.4 7.4 3.6 19.6 3.3 1.3 8.3 7.9 0.7 1.8 1.7 5.1 1.7 10.3 7.9 6.6 3.4 5.3 8.3 5.5 1.5 3.1 2.3 13.4 4.0 0.4 3.1 0.2 3.2 9.8 0.0 6.4 3.4 6.2 6.2 2.3 0.1 1.1 0.9 0.3 0.4 1.2 0.6 1.4 0.7 0.3 0.3 0.6 0.4 2.7 0.3 0.9 1.8 0.3 2.4 8.3 3.9 3.0 2.1 4.4 2.9 5.3 3.6 1.9 4.5 2.6 9.1 41.7 16.2 46.4 24.1 8.4 23.6 9.2 12.0 18.3 28.9 11.9 28.3 15.7 17.3 14.7 25.0 10.4 22.1 65.5 17.6 9.7 26.8 7.9 5.7 6.5 14.4 8.0 101.3 23.1 9.7 10.9 20.9 17.1 64.7 12.8 9.3 15.3 18.9 5.0 138.5 27.4 4.1 18.9 82.4 26.8 23.9 30.0 16.0 42.2 15.8 8.6 28.8 75.4 5.8 22.5 54.5 13.2 50.7 21.9 59.9 16.4 9.6 14.0 0.0 13.9 6.3 8.1 13.9 22.9 12.1 7.4 42.5 5.7 27.9 53.5 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DENND2C "dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1" ENSG00000175984 "DENN domain containing 2C" Q68D51 1 114582848-114670422 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.7;skeletal muscle: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.1;Basal prostatic cells: 138.2;Glandular and luminal cells: 192.7;Squamous epithelial cells: 114.9;Suprabasal keratinocytes: 171.8;Urothelial cells: 340.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "U-2197: 11.8;U-266/70: 25.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029935, HPA054955" Uncertain Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA029935: AB_10601208, HPA054955: AB_2682648" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "unprognostic (9.97e-2)" "unprognostic (4.89e-4)" "unprognostic (1.52e-1)" "unprognostic (2.46e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (2.20e-2)" "unprognostic (7.43e-2)" "unprognostic (2.77e-2)" "unprognostic (2.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.57e-2)" 0.9 0.5 0.8 0.3 0.8 1.0 1.9 0.9 0.9 4.2 2.2 0.6 0.7 1.5 0.8 17.7 0.9 1.2 1.1 1.1 0.4 0.6 2.0 1.5 0.4 0.6 0.6 1.1 1.2 1.7 0.6 0.1 0.7 1.4 0.6 1.5 2.7 1.4 41.6 12.4 0.6 1.1 0.3 0.4 0.9 5.5 0.6 0.4 1.4 1.7 3.4 2.6 7.0 0.5 2.1 0.0 0.1 1.4 1.7 1.8 0.4 0.6 1.1 0.7 1.1 0.3 0.0 0.1 0.9 4.1 1.4 7.4 1.4 4.6 0.7 0.1 1.8 1.2 0.4 0.1 0.5 0.0 1.8 1.8 4.4 2.7 2.3 0.1 0.2 0.5 0.2 0.3 2.4 6.0 0.2 0.1 0.9 0.0 1.1 0.0 6.2 0.1 0.1 5.7 0.0 0.0 4.5 0.1 0.5 1.1 0.9 0.3 0.3 1.0 1.5 11.8 0.2 25.4 4.8 0.0 1.0 0.0 0.8 3.0 0.0 0.9 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.8 0.8 0.9 0.9 1.1 0.4 0.6 0.6 0.7 0.3 0.6 0.5 6.6 28.9 2.2 3.3 3.3 109.1 138.2 32.5 60.3 20.4 5.2 5.3 8.7 11.5 21.3 7.3 20.9 0.1 1.9 1.1 0.0 7.2 29.5 100.3 15.7 8.6 0.0 0.0 2.8 7.5 0.1 6.9 5.6 192.7 2.5 8.1 15.4 11.7 0.3 0.0 0.8 0.9 4.1 2.2 9.3 12.9 5.0 14.0 7.2 9.4 1.1 2.3 1.0 5.0 3.5 33.0 0.2 2.2 17.6 79.5 0.1 0.8 46.8 10.3 0.0 21.7 6.6 47.9 59.7 114.9 171.8 0.0 3.7 1.3 1.5 340.4 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 34.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.1;Cone photoreceptor cells: 189.7;Inhibitory neurons: 90.0;Rod photoreceptor cells: 165.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 84.8;MOLT-4: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 4.1 2.2 5.4 4.5 6.9 3.1 3.0 9.4 7.4 4.9 7.7 4.9 2.6 6.5 4.2 2.6 4.8 4.6 2.9 5.8 8.1 2.6 2.8 5.2 5.0 3.3 4.7 3.5 3.9 4.1 6.2 2.7 3.4 4.1 3.3 34.5 2.5 3.3 1.2 1.9 4.4 4.3 2.7 6.9 3.7 6.5 6.9 9.8 4.0 2.2 4.3 3.8 4.2 5.8 3.5 3.3 3.0 0.3 0.6 1.0 1.4 5.8 4.7 3.9 4.5 7.7 4.2 5.1 7.0 3.1 1.9 4.2 7.2 3.2 7.8 16.5 9.5 6.6 8.9 5.1 3.3 12.7 8.9 1.9 4.0 4.1 8.0 3.6 5.4 14.7 5.5 84.8 4.8 5.1 30.3 7.1 2.3 4.6 10.0 9.4 12.4 12.2 3.9 7.6 4.7 3.2 4.7 2.5 0.2 1.9 5.3 6.0 5.0 1.1 5.4 1.7 0.9 11.3 25.3 3.4 3.3 7.3 0.3 0.1 0.2 0.0 1.0 0.1 0.7 0.9 0.6 0.7 0.2 0.3 0.7 0.9 0.3 0.7 0.2 0.8 1.7 0.3 5.4 6.9 9.4 7.4 5.8 8.1 3.3 4.7 3.4 2.7 6.9 5.8 51.2 3.2 6.0 10.4 11.3 8.9 13.5 3.1 21.6 181.1 5.0 6.3 6.3 10.0 4.0 16.5 189.7 6.6 16.3 5.6 0.0 7.4 18.3 9.0 9.9 30.6 11.3 2.1 66.0 4.7 3.0 6.9 9.7 19.3 0.0 13.1 29.3 4.0 2.2 8.4 90.0 7.7 8.2 5.0 9.3 9.2 4.4 7.4 3.6 32.8 6.3 18.6 14.4 32.6 14.4 6.0 6.4 5.3 15.1 21.3 1.9 0.1 2.8 165.4 6.6 11.8 10.7 28.5 20.7 9.7 6.7 3.4 18.9 5.7 5.8 13.4 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DHRS12 "FLJ13639, SDR40C1" ENSG00000102796 "Dehydrogenase/reductase 12" A0PJE2 13 51767993-51804162 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 66.8" "Cell type enhanced" "Detected in many" "Late spermatids: 69.1;Proximal tubular cells: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB034238, HPA057028, HPA058315" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Vesicles" "CAB034238: AB_2091845, HPA057028: AB_2683314, HPA058315: AB_2683678" "prognostic favorable (1.41e-4)" "unprognostic (1.98e-2)" "unprognostic (2.98e-1)" "unprognostic (7.57e-2)" "unprognostic (2.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.47e-3)" "unprognostic (1.70e-1)" "unprognostic (3.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.21e-2)" "unprognostic (3.98e-1)" "prognostic favorable (2.22e-16)" "unprognostic (2.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.03e-2)" "unprognostic (3.44e-1)" 22.7 10.6 7.8 2.9 7.3 4.5 20.5 8.9 7.8 13.9 6.5 14.0 5.5 13.1 5.0 10.3 14.5 6.1 14.3 7.3 6.7 24.6 28.9 11.7 5.3 7.2 6.6 18.4 66.8 6.6 18.7 3.6 7.0 15.4 3.7 5.9 15.0 5.9 16.0 14.1 12.5 4.0 7.6 15.7 15.0 8.2 7.0 2.3 18.8 4.1 3.5 13.2 11.2 8.3 1.1 2.5 3.8 5.6 1.2 2.6 4.4 1.6 4.1 1.8 1.3 4.5 8.6 4.2 1.2 2.5 2.5 2.0 0.0 0.3 0.3 4.2 3.4 0.6 1.1 3.2 6.6 0.4 0.7 2.7 3.9 0.6 2.4 4.5 5.2 4.0 2.0 3.0 1.3 5.5 1.0 3.5 6.1 4.2 0.6 0.5 0.8 5.8 5.6 3.2 3.4 6.9 2.9 2.5 7.1 5.0 2.8 2.8 3.7 1.3 1.5 0.1 1.7 1.4 1.8 1.9 2.3 1.4 3.7 6.6 16.6 0.5 14.0 14.2 24.1 13.7 19.7 16.9 9.0 13.4 16.4 12.9 31.4 3.8 16.5 10.6 19.8 13.5 7.8 7.3 8.9 7.8 7.3 6.7 7.2 6.6 7.0 7.6 7.0 8.3 14.1 12.8 14.8 11.1 11.4 11.3 12.1 22.2 10.8 11.9 23.5 22.9 15.7 18.6 13.3 16.5 8.4 24.9 8.0 7.8 52.8 12.5 26.1 5.6 7.7 10.1 10.3 2.1 4.9 16.7 17.5 17.1 7.1 6.4 12.0 6.8 8.6 30.7 17.1 3.3 5.4 12.4 22.4 11.2 11.6 69.1 11.1 10.1 14.2 3.7 10.5 32.4 8.2 24.6 12.9 12.6 21.9 9.8 4.8 12.2 25.5 83.5 19.5 18.5 0.0 14.2 11.4 1.4 8.2 10.5 14.9 23.8 13.7 13.4 11.0 12.2 DIRAS3 "ARHI, NOEY2" ENSG00000162595 "DIRAS family GTPase 3" O95661 1 68045886-68051631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 143.9;ovary: 60.1;pituitary gland: 52.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 64.6;Theca cells: 206.2" "Group enriched" "Detected in many" 4 "endometrial cancer: 4.3;glioma: 16.3;pancreatic cancer: 5.6;thyroid cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 8.2;HSkMC: 17.2;TIME: 11.2;U-251 MG: 9.1;U-87 MG: 16.9" "Low region specificity" "Detected in all" "HPA028483, HPA028557, HPA029384" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Cytosol" "HPA028483: AB_10599599, HPA028557: AB_10602091, HPA029384: AB_10601343" "prognostic favorable (9.21e-4)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-2)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (7.86e-2)" "unprognostic (8.35e-2)" "unprognostic (4.33e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.34e-1)" "unprognostic (4.99e-1)" "unprognostic (1.24e-2)" "unprognostic (5.07e-3)" 1.4 20.1 25.3 0.5 18.7 0.1 5.0 2.2 11.5 5.2 3.0 3.3 7.5 2.5 10.6 1.7 3.3 10.2 11.3 7.0 143.9 6.9 9.5 5.1 0.2 39.6 49.2 60.1 20.0 7.5 52.5 0.6 18.5 2.9 0.8 4.0 2.3 2.6 1.1 2.1 1.4 1.2 7.8 2.5 4.2 5.5 104.7 1.6 3.8 1.9 0.3 3.1 6.4 8.0 0.0 1.5 1.6 0.0 5.2 3.9 0.6 4.6 1.6 0.3 1.2 0.0 0.8 0.0 0.2 4.8 0.1 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.6 0.0 8.2 0.0 0.0 17.2 0.1 0.7 0.0 0.0 1.0 0.2 0.3 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.1 0.5 0.1 0.0 11.2 0.0 0.5 0.2 9.1 2.7 0.0 0.0 16.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 25.3 18.7 2.2 11.5 7.0 143.9 39.6 49.2 18.5 7.8 104.7 8.0 0.3 0.0 1.8 5.2 0.0 3.2 25.0 0.6 0.6 1.1 5.4 6.5 5.9 7.2 2.5 3.7 10.4 1.1 0.0 0.4 64.6 3.7 0.1 0.7 0.7 1.7 16.2 0.0 2.2 18.7 0.1 10.3 4.1 1.8 0.0 0.8 3.3 3.9 0.1 0.0 8.8 2.3 0.0 0.0 4.8 0.8 6.8 0.3 5.4 0.0 0.0 0.7 1.0 5.0 0.2 2.9 0.1 1.5 0.0 5.3 0.1 11.1 0.9 6.1 0.0 16.9 1.7 0.0 1.4 1.7 2.8 0.4 0.7 206.2 0.7 2.4 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" Q14184 17 142789-181650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 24.6" "Group enriched" "Detected in many" 5 "Adipocytes: 49.4;Cone photoreceptor cells: 175.2;Muller glia cells: 146.7;Rod photoreceptor cells: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 37.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 56.1" HPA043168 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA043168: AB_2678349" "prognostic favorable (3.45e-4)" "unprognostic (2.28e-3)" "unprognostic (3.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "prognostic favorable (8.68e-4)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.78e-3)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (2.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (4.87e-3)" 15.9 4.5 11.6 3.0 12.7 6.2 13.9 18.6 21.1 3.7 1.3 4.0 0.0 4.0 0.0 14.4 5.8 0.0 5.3 22.5 6.5 8.7 0.7 3.4 1.3 8.7 11.7 1.1 10.0 0.2 6.7 1.4 10.8 3.6 1.1 24.6 2.1 0.6 2.7 4.4 4.5 1.5 12.6 3.3 3.4 0.3 12.2 0.8 3.0 0.1 2.5 4.4 5.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 12.7 18.6 21.1 22.5 6.5 8.7 11.7 10.8 12.6 12.2 0.9 49.4 0.0 2.3 0.3 0.2 0.0 0.8 0.0 2.2 10.1 1.5 1.3 2.0 0.0 0.0 9.2 175.2 0.0 0.0 0.2 0.0 0.2 1.1 0.7 4.6 22.8 0.0 0.0 3.8 4.2 0.0 2.3 9.2 0.8 0.0 0.1 18.5 0.2 0.1 1.7 2.3 0.0 0.0 0.3 0.0 2.5 0.0 0.5 0.0 1.0 0.6 146.7 0.0 1.5 0.1 4.3 0.0 0.0 0.0 0.9 0.0 0.5 1.5 100.7 0.0 2.3 0.8 0.2 0.1 1.8 0.0 0.3 0.1 0.8 0.2 3.6 DOCK1 "ced5, DOCK180" ENSG00000150760 "Dedicator of cytokinesis 1" Q14185 10 126905409-127452517 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 186.4;Oligodendrocyte precursor cells: 331.3;Oligodendrocytes: 429.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004378, HPA048692, HPA053277" Approved Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "CAB004378: AB_2094604, HPA048692: AB_2680495, HPA053277: AB_2682097" "unprognostic (4.27e-2)" "unprognostic (4.22e-3)" "unprognostic (1.49e-3)" "unprognostic (8.98e-3)" "unprognostic (2.57e-2)" "unprognostic (3.31e-1)" "unprognostic (4.12e-1)" "unprognostic (4.80e-2)" "unprognostic (6.85e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-2)" "unprognostic (2.42e-1)" "unprognostic (2.61e-3)" "unprognostic (1.87e-1)" "unprognostic (3.85e-2)" "unprognostic (1.18e-1)" "unprognostic (4.83e-2)" 19.9 8.2 38.1 7.3 54.3 0.7 19.9 39.1 34.6 23.3 22.5 17.7 13.4 19.6 15.5 16.1 18.1 17.2 14.2 29.9 37.2 19.3 9.6 13.7 4.6 44.7 51.8 24.7 14.1 25.6 5.6 19.6 44.5 16.5 13.8 2.3 17.7 18.4 5.2 33.4 15.1 19.2 35.6 9.9 13.3 6.9 45.3 8.5 26.6 10.6 5.7 16.5 18.9 50.1 16.1 29.8 57.2 41.2 29.2 38.7 12.6 31.5 66.2 21.9 23.1 18.8 18.0 0.0 10.3 47.4 19.8 18.0 18.4 23.8 25.4 0.3 17.9 10.0 18.8 22.7 28.9 0.0 14.2 31.8 7.0 22.7 49.3 53.0 51.3 0.0 0.0 0.1 33.1 16.4 0.0 0.0 14.1 12.4 13.5 0.0 37.3 0.4 22.1 17.5 3.4 24.5 32.9 18.6 28.9 40.6 4.7 0.1 54.2 39.7 15.3 9.8 30.7 0.0 0.1 0.0 31.3 0.0 25.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 38.1 54.3 39.1 34.6 29.9 37.2 44.7 51.8 44.5 35.6 45.3 50.1 55.9 32.1 20.3 186.4 0.4 17.2 15.5 9.5 43.9 0.5 18.5 17.3 11.8 12.8 17.9 22.0 0.0 14.1 3.2 28.0 0.0 14.7 11.3 20.2 36.8 35.2 5.4 1.7 2.4 7.1 11.5 27.7 16.8 17.1 0.0 33.3 26.4 7.8 5.7 0.0 4.8 15.3 6.1 4.6 5.9 24.5 32.6 5.1 7.2 105.9 2.8 6.6 0.0 331.3 429.1 13.6 9.4 36.5 0.1 13.7 17.5 11.5 20.6 1.2 13.1 30.5 24.1 2.0 6.7 21.5 16.2 12.6 1.1 35.4 12.3 10.3 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 110.7;Distal tubular cells: 39.2;Excitatory neurons: 49.7;Horizontal cells: 38.7;Inhibitory neurons: 79.6;Muller glia cells: 63.9;Oligodendrocyte precursor cells: 58.3" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 32.9;ASC diff: 13.1;ASC TERT1: 11.0;hTEC/SVTERT24-B: 13.7;U-138 MG: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 2.9 1.9 14.6 1.7 14.2 0.0 1.9 13.4 15.6 1.1 13.0 1.4 0.3 1.7 0.3 1.7 12.2 9.8 18.4 15.4 16.9 5.2 2.3 1.0 0.6 15.9 14.7 0.9 1.2 0.2 1.1 1.8 18.6 0.9 0.7 11.7 1.4 0.8 46.0 0.5 0.7 2.8 13.9 0.3 0.8 1.7 15.3 0.4 5.1 24.3 0.4 4.7 0.9 13.3 0.0 0.0 32.9 0.0 13.1 11.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 4.3 0.0 13.7 0.0 0.6 1.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 3.6 7.0 0.0 8.6 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.0 51.3 3.2 1.4 0.0 0.0 0.0 0.1 2.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 14.2 13.4 15.6 15.4 16.9 15.9 14.7 18.6 13.9 15.3 13.3 4.8 0.0 0.0 110.7 0.3 0.3 2.3 0.0 0.0 12.3 6.7 6.2 7.3 12.8 0.0 11.0 6.2 0.3 0.1 0.0 39.2 17.7 2.3 0.4 1.5 3.3 0.0 0.0 49.7 1.2 0.6 14.4 0.0 10.6 0.0 28.6 17.5 0.0 29.0 38.7 79.6 0.0 0.0 0.6 2.5 4.5 2.5 0.6 0.0 9.4 14.5 63.9 0.0 58.3 2.1 2.2 0.0 1.2 0.1 2.0 0.0 0.2 0.0 8.1 0.0 2.8 5.3 3.7 1.5 0.0 0.4 0.8 0.2 1.6 0.0 0.9 DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 230.4;Excitatory neurons: 236.8;Inhibitory neurons: 259.1;Oligodendrocyte precursor cells: 178.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.5;Hep G2: 11.1;RPMI-8226: 10.5;SCLC-21H: 4.7;SH-SY5Y: 10.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" 1.1 0.7 8.8 0.7 10.3 0.1 0.5 0.9 14.0 1.8 0.0 0.6 0.3 1.5 0.5 0.7 0.7 3.2 6.2 17.8 10.6 4.9 2.4 2.4 0.5 10.9 11.6 2.2 0.2 12.5 0.7 5.9 9.7 1.3 0.5 22.3 0.8 2.1 0.1 0.5 0.5 2.5 4.1 0.9 0.7 1.5 6.5 0.1 2.2 0.6 0.5 3.1 1.1 5.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.0 11.1 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 10.5 0.0 0.0 4.7 10.5 0.0 0.0 0.0 7.6 0.0 0.0 0.0 4.0 0.6 0.0 1.5 0.3 0.0 0.0 3.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.3 0.9 14.0 17.8 10.6 10.9 11.6 9.7 4.1 6.5 5.8 0.5 0.0 0.0 9.8 0.0 0.3 0.1 0.0 0.0 230.4 0.1 0.0 9.1 0.0 1.3 0.0 14.6 0.0 1.2 0.0 1.9 0.0 45.3 0.4 13.3 1.5 0.0 0.0 236.8 0.0 0.0 6.7 0.0 0.3 0.0 17.2 0.0 0.9 0.0 10.1 259.1 0.0 0.0 0.3 0.8 30.6 1.5 2.1 0.0 8.4 0.1 6.9 2.1 178.4 6.4 0.0 0.0 6.8 0.7 0.1 0.0 9.6 0.0 14.6 0.0 0.4 5.5 0.9 1.1 0.1 0.6 0.0 1.2 4.9 0.0 0.1 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.3;testis: 83.8" "Group enriched" "Detected in many" 12 "Early spermatids: 179.4;Late spermatids: 580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favorable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 9.5 19.6 4.8 2.7 4.8 4.7 10.9 4.1 6.2 12.5 4.8 12.4 5.3 11.9 7.8 11.7 13.8 3.3 20.0 4.7 3.6 16.2 7.5 8.8 4.6 3.5 3.4 11.6 10.3 6.5 31.5 2.7 3.6 13.0 2.1 4.1 14.3 3.3 131.3 14.8 10.2 2.6 1.2 14.0 12.1 83.8 3.6 5.2 16.5 49.9 2.5 11.4 10.5 3.0 0.4 9.3 8.8 6.2 4.9 4.6 0.7 2.9 1.8 2.6 2.3 0.9 3.6 1.4 11.0 3.4 0.1 3.2 1.3 2.0 2.3 5.4 7.8 0.6 5.9 0.9 4.1 0.3 1.9 6.2 1.2 0.8 2.9 8.6 0.6 3.5 1.5 2.0 0.4 4.7 2.1 0.8 2.2 2.7 2.1 1.0 0.2 0.6 5.7 2.2 12.7 14.5 4.5 4.4 0.2 4.6 4.4 0.5 4.5 1.1 2.0 1.0 0.9 3.2 1.1 1.0 7.4 0.9 0.4 0.7 1.6 1.8 3.0 1.7 3.6 2.4 2.0 3.1 1.9 1.6 1.0 1.7 2.5 3.3 1.6 4.5 2.2 1.7 4.8 4.8 4.1 6.2 4.7 3.6 3.5 3.4 3.6 1.2 3.6 3.0 6.0 0.0 0.6 6.2 10.9 3.4 3.8 8.4 10.2 15.2 9.0 6.1 6.1 7.2 3.4 16.5 20.9 2.1 21.7 10.3 9.8 13.1 179.4 15.4 6.7 7.3 20.4 19.8 4.6 4.3 1.7 5.1 7.7 10.1 1.3 11.9 12.1 3.9 5.9 10.1 6.3 9.8 10.2 8.2 3.0 580.2 7.2 4.7 5.4 7.5 5.7 8.3 10.3 5.0 3.2 9.7 9.7 5.3 5.0 4.8 11.5 17.4 10.7 13.0 0.0 11.1 4.8 30.1 13.4 6.1 2.8 1.4 10.8 20.2 7.4 3.6 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 EDA2R "EDA-A2R, EDAA2R, TNFRSF27, XEDAR" ENSG00000131080 "Ectodysplasin A2 receptor" Q9HAV5 X 66595637-66639298 "Predicted membrane proteins" Differentiation "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 8.3;Microglial cells: 5.6;Oligodendrocytes: 6.4;Theca cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 24.3;HSkMC: 33.3;LHCN-M2: 31.8;SuSa: 25.2" "Not detected" "Not detected" HPA054522 Approved "Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Cell Junctions" "HPA054522: AB_2682516" "unprognostic (1.31e-3)" "unprognostic (3.17e-3)" "unprognostic (2.19e-1)" "unprognostic (8.49e-3)" "unprognostic (4.15e-3)" "unprognostic (3.63e-3)" "unprognostic (2.48e-2)" "unprognostic (3.37e-2)" "unprognostic (2.82e-1)" "unprognostic (7.17e-2)" "unprognostic (6.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (8.23e-2)" "unprognostic (4.92e-2)" "unprognostic (3.08e-1)" 2.1 5.7 1.7 0.5 2.4 0.0 3.0 1.9 2.1 6.1 3.8 2.2 0.3 5.7 4.2 2.4 4.3 3.3 2.1 1.7 1.8 1.2 0.8 2.6 0.5 2.5 1.8 7.5 3.1 3.0 3.4 1.1 2.7 4.0 4.9 0.7 2.5 5.4 2.4 1.5 1.1 5.2 2.2 1.2 0.8 1.4 2.3 2.6 5.6 0.9 0.4 2.4 4.3 3.7 0.0 16.4 15.0 0.0 21.0 24.3 0.2 22.5 24.0 2.1 3.3 0.0 0.0 8.3 0.0 14.6 0.0 0.1 0.0 8.6 7.3 0.0 7.8 0.0 0.5 11.0 3.7 0.0 0.1 33.3 20.0 16.4 15.1 20.2 0.5 0.4 0.8 8.4 31.8 1.9 0.4 0.0 5.6 0.0 0.0 0.0 2.0 0.0 1.5 0.0 0.0 2.7 0.0 0.0 0.0 25.2 0.5 0.3 17.3 0.0 12.0 0.0 0.2 0.0 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.9 2.1 1.7 1.8 2.5 1.8 2.7 2.2 2.3 3.7 0.5 3.2 0.0 0.7 0.8 0.3 1.0 1.5 2.8 0.1 1.2 1.7 0.5 1.5 1.4 1.8 0.0 1.2 0.1 0.0 0.0 0.2 0.0 0.5 1.2 0.6 1.2 0.0 0.0 0.6 1.3 2.5 0.5 0.2 0.0 8.3 0.7 0.0 0.2 0.0 0.3 0.5 2.0 0.0 0.3 0.0 1.8 0.1 1.8 5.6 0.0 1.5 1.0 2.0 6.4 0.6 0.3 0.4 0.0 1.1 0.2 0.4 1.0 0.0 0.0 3.6 1.6 0.0 0.2 0.7 0.6 0.7 0.6 5.0 0.5 0.6 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGR2 KROX20 ENSG00000122877 "Early growth response 2" P11161 10 62811996-62919900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 59.9;thyroid gland: 136.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 55.5;Breast myoepithelial cells: 68.1;Enteroendocrine cells: 73.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 19.7" "Group enriched" "Detected in many" 5 "cerebral cortex: 10.2;hippocampal formation: 5.2" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "U-87 MG: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031165 Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031165: AB_2673768" "prognostic favorable (7.30e-5)" "unprognostic (1.86e-3)" "unprognostic (1.45e-2)" "unprognostic (8.72e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (9.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-3)" "unprognostic (6.54e-2)" "unprognostic (1.74e-2)" "unprognostic (3.46e-1)" "unprognostic (1.11e-3)" 13.7 10.6 0.4 9.8 1.2 8.2 8.6 1.3 10.2 18.5 2.0 3.3 1.9 6.0 59.9 8.8 4.5 31.9 14.9 5.2 0.2 7.9 5.4 15.2 14.4 0.3 0.3 9.4 4.2 7.0 8.7 3.0 0.7 17.5 3.7 1.4 2.9 1.9 0.9 14.2 4.6 16.8 0.1 4.5 2.3 4.1 0.6 26.4 136.4 9.1 7.1 15.7 1.7 1.5 0.0 0.2 2.5 1.0 1.8 2.4 0.4 0.5 0.2 0.6 0.8 0.0 0.3 0.6 0.0 0.6 0.7 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 3.8 0.3 0.6 1.3 0.2 0.8 0.1 0.3 0.2 0.8 0.1 1.2 0.0 1.8 0.2 0.1 1.1 0.1 0.3 0.4 0.0 0.2 0.1 0.3 0.2 0.5 4.2 0.5 0.0 0.5 0.1 0.5 0.4 0.2 0.3 1.3 0.7 0.3 22.5 0.5 0.4 0.0 0.5 0.2 0.1 2.5 0.0 0.4 0.0 0.1 0.5 0.4 0.0 0.1 0.7 0.2 2.3 0.0 0.0 0.4 0.4 1.2 1.3 10.2 5.2 0.2 0.3 0.3 0.7 0.1 0.6 1.5 15.9 0.0 12.6 0.0 14.0 21.3 30.1 36.0 33.0 1.4 55.5 68.1 7.8 0.0 9.4 0.0 0.0 1.1 9.9 9.5 0.0 1.4 8.9 13.9 14.0 16.7 73.1 0.0 1.7 0.6 1.6 30.4 13.3 26.1 20.8 2.3 5.3 2.4 25.2 0.0 0.5 29.4 14.2 28.1 39.5 4.3 1.8 40.5 8.8 0.0 0.8 4.1 0.0 0.0 0.1 1.0 4.4 7.2 6.4 5.5 7.7 0.0 7.1 0.7 6.6 20.7 12.0 0.1 2.0 14.8 12.5 1.1 13.6 5.1 25.8 3.1 EGR3 PILOT ENSG00000179388 "Early growth response 3" Q06889 8 22687659-22693480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;skin 1: 45.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 284.3;Glandular and luminal cells: 116.6;granulocytes: 108.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 47.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HMC-1: 9.5;MCF7: 31.9;SK-MEL-30: 22.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 19.3;basal ganglia: 52.5;cerebral cortex: 47.8;hippocampal formation: 41.3;olfactory bulb: 33.7" "HPA006206, CAB009373" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB009373: AB_2097202, HPA006206: AB_10602491" "prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "unprognostic (4.07e-2)" "unprognostic (1.00e-1)" "unprognostic (6.44e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.48e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.11e-2)" "unprognostic (4.72e-2)" "unprognostic (2.35e-2)" "unprognostic (1.07e-2)" 29.0 24.5 7.7 19.0 9.9 10.1 10.3 0.6 47.2 9.5 0.0 4.6 1.5 5.6 0.4 5.9 17.3 30.0 12.1 16.1 0.0 5.8 2.9 5.8 11.4 5.1 0.0 15.3 4.5 13.8 6.8 1.0 2.0 14.4 3.2 4.5 3.1 0.9 1.9 45.6 3.9 12.5 1.3 3.3 6.5 5.4 0.0 19.5 8.4 3.2 5.9 14.8 3.6 5.8 0.2 0.0 0.2 0.3 1.8 5.5 0.1 0.6 0.6 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.4 0.5 0.2 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.5 0.6 0.2 0.2 0.0 0.8 0.1 0.2 0.3 0.1 0.0 31.9 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.5 0.0 22.5 0.3 1.4 0.1 0.0 0.3 0.1 0.2 0.4 0.4 0.1 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 9.9 0.6 47.2 16.1 0.0 5.1 0.0 2.0 1.3 0.0 5.8 80.2 6.4 11.2 0.3 46.7 23.1 31.9 43.8 39.3 2.3 73.0 68.2 47.1 0.0 12.2 0.0 0.0 1.3 9.3 3.5 0.0 3.3 18.4 47.1 52.7 36.5 284.3 0.0 16.0 4.2 1.3 33.9 35.2 116.6 108.7 21.8 37.5 0.5 4.7 0.0 0.9 19.2 8.2 19.0 20.3 11.6 3.1 27.8 21.4 3.7 0.0 5.1 0.0 1.0 0.7 4.5 2.2 0.4 3.7 16.1 0.2 0.1 5.7 1.3 0.0 41.3 35.9 0.3 0.2 16.5 50.0 9.7 11.5 6.5 7.0 9.8 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 34.3;Granulosa cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" 12.2 3.7 1.8 14.6 1.6 53.1 9.6 2.8 2.0 9.4 2.6 18.1 14.2 10.6 2.0 11.7 12.1 9.3 5.6 1.8 2.4 6.0 2.8 15.9 18.3 2.8 2.4 17.5 2.6 4.8 4.2 23.7 2.4 6.1 17.7 0.6 5.5 4.1 2.0 10.9 17.0 10.6 1.5 18.1 20.3 2.6 2.9 19.6 3.9 3.6 18.0 18.8 9.1 3.1 56.0 20.7 3.7 0.4 9.1 19.3 52.6 25.3 32.1 30.4 33.4 28.7 38.9 28.6 49.5 34.8 42.3 35.2 20.5 30.0 29.9 31.0 16.8 56.7 27.3 13.6 20.2 49.7 69.3 20.4 32.6 49.1 48.0 19.0 30.0 6.5 22.0 7.7 16.5 32.8 8.2 28.2 2.4 28.4 19.4 17.6 6.5 12.2 18.3 63.9 13.6 6.0 22.8 21.9 6.9 19.1 11.0 46.9 27.6 21.2 16.6 39.5 47.7 4.2 1.8 22.6 24.6 44.8 5.0 1.6 4.0 5.8 7.1 7.6 5.6 2.6 4.2 6.1 4.5 2.7 4.2 4.8 6.9 6.5 5.5 2.7 4.8 4.2 1.8 1.6 2.8 2.0 1.8 2.4 2.8 2.4 2.4 1.5 2.9 3.1 10.7 9.6 4.4 0.0 8.0 13.6 8.2 2.9 9.1 0.0 2.1 1.5 0.8 0.0 4.4 0.0 0.0 10.6 12.2 24.1 0.0 2.3 0.1 8.9 3.8 8.4 9.0 7.4 0.2 4.0 34.3 6.4 17.9 17.1 1.3 27.5 6.4 1.0 9.7 0.0 0.3 8.3 2.0 12.2 9.2 0.6 1.8 14.8 3.6 5.6 13.1 0.0 16.5 0.0 1.2 9.1 17.4 1.2 2.0 7.5 11.6 0.3 5.4 0.0 6.6 2.6 2.5 0.0 4.0 6.5 10.4 11.2 9.5 5.2 7.1 18.9 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "CAB017042: , HPA047752: AB_2680147, HPA054197: AB_2682413" "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (2.76e-2)" 242.4 134.7 51.3 74.9 67.0 114.6 199.2 74.6 79.2 48.9 49.4 40.0 28.3 39.8 49.7 28.4 46.0 51.3 37.8 50.8 65.3 38.9 108.9 68.4 106.7 80.7 69.0 32.3 15.4 24.3 28.5 40.2 74.5 128.0 18.3 36.5 24.8 103.0 9.9 32.9 47.5 52.4 67.7 56.1 22.8 82.5 65.8 107.3 45.1 19.5 102.4 67.1 27.0 98.9 137.2 98.1 168.0 309.0 436.0 250.8 71.3 155.8 174.2 123.2 171.5 87.4 154.5 154.4 110.3 163.3 193.1 78.9 168.0 142.6 183.7 131.2 117.5 153.1 85.0 122.9 239.0 122.2 107.2 233.6 109.8 123.6 153.9 124.5 139.1 301.4 194.2 87.3 90.3 14.9 364.4 107.9 91.2 5.2 73.6 139.9 115.3 54.3 232.7 80.6 155.7 107.1 129.3 66.9 135.2 108.7 152.3 112.9 133.0 134.7 118.5 242.2 208.8 72.8 72.1 116.2 70.2 173.6 97.8 47.6 49.2 183.7 34.9 34.9 56.5 88.4 58.1 42.7 77.9 101.5 27.8 26.3 261.5 36.7 45.0 20.4 110.0 50.6 51.3 67.0 74.6 79.2 50.8 65.3 80.7 69.0 74.5 67.7 65.8 98.9 48.6 80.1 50.7 75.4 118.3 52.4 108.2 36.8 44.3 11.6 177.3 70.9 23.3 21.5 40.2 12.9 2.1 25.3 55.5 2.1 15.6 34.9 94.2 37.4 53.2 54.4 25.0 77.0 25.8 36.1 58.2 54.8 3.1 66.4 99.0 28.4 39.3 88.7 35.5 8.4 29.8 1.6 16.2 57.3 114.6 181.0 20.8 55.5 48.0 39.4 53.5 83.2 39.1 49.3 111.2 27.8 1.4 32.0 45.2 169.2 21.9 48.4 58.5 6.0 65.7 27.3 77.5 27.0 18.9 35.7 60.9 31.2 97.2 60.0 4.4 73.4 ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.4;Hepatocytes: 102.0;Inhibitory neurons: 78.5;Oligodendrocytes: 77.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 2.4;MAIT T-cell: 2.6;memory CD4 T-cell: 1.0;memory CD8 T-cell: 1.3;naive CD8 T-cell: 1.0;NK-cell: 3.3" "Group enriched" "Detected in many" 21 "NK-cells: 3.3;T-cells: 2.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favorable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" 12.2 8.7 4.6 2.9 5.2 4.0 7.4 5.2 7.9 4.2 1.5 11.5 8.5 3.1 2.1 18.0 2.1 3.2 4.2 4.9 5.0 4.0 36.2 3.1 0.7 5.8 5.4 1.5 2.0 6.4 4.0 1.7 6.0 1.9 10.2 12.1 4.1 2.3 1.0 15.3 6.3 3.7 5.8 1.6 13.6 0.9 5.3 1.8 1.8 0.5 2.3 6.8 5.7 7.8 24.1 14.5 57.8 12.9 31.6 32.6 24.6 16.8 9.5 6.4 16.4 7.6 45.5 2.5 1.3 13.3 22.0 21.5 46.8 52.2 13.6 9.5 14.8 33.9 17.3 17.9 19.6 30.4 18.8 30.0 10.2 34.9 13.5 21.5 11.9 3.4 33.8 57.0 12.6 10.5 7.1 2.6 25.0 15.3 7.2 4.3 24.1 7.2 37.2 20.3 11.0 23.3 9.9 57.9 9.1 24.3 10.0 0.3 5.9 13.2 15.5 20.4 21.4 2.7 11.3 57.9 20.8 0.0 2.8 0.1 0.0 0.0 2.4 0.0 2.6 0.0 1.0 1.3 0.0 0.0 0.3 1.0 0.1 3.3 0.0 0.0 0.1 0.4 4.6 5.2 5.2 7.9 4.9 5.0 5.8 5.4 6.0 5.8 5.3 7.8 2.1 0.0 7.8 51.2 1.6 1.8 3.0 8.6 2.8 24.4 3.8 2.8 3.2 8.6 9.8 11.0 37.5 2.5 8.9 38.1 5.9 13.0 7.6 3.5 11.1 2.2 3.0 34.9 83.4 8.2 26.8 6.9 30.5 6.3 6.3 8.3 4.2 102.0 1.9 26.9 78.5 14.4 8.2 3.0 0.3 3.9 1.2 0.7 0.0 18.7 0.1 5.5 18.6 56.3 77.3 16.6 24.8 1.2 2.9 2.5 7.1 6.9 2.9 16.3 6.6 6.4 7.5 0.2 1.5 19.9 7.0 2.1 9.6 11.8 22.4 5.1 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.2;Oligodendrocytes: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "GAMG: 41.9;HDLM-2: 29.3;HEL: 37.3" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 10.5 5.5 23.1 2.2 24.9 1.0 22.1 29.5 26.5 3.6 36.2 8.8 11.8 2.2 0.9 5.0 2.8 19.3 0.9 18.3 30.0 16.2 1.0 3.8 2.5 31.8 26.3 0.5 8.5 21.0 2.7 0.8 32.9 22.0 11.5 10.5 4.7 1.2 0.5 26.2 21.3 3.7 30.1 0.5 3.3 0.8 32.9 1.8 16.8 1.0 4.0 7.6 6.7 32.2 20.7 7.6 0.1 0.5 0.0 0.0 18.6 0.0 4.3 2.5 8.4 9.6 21.4 0.0 9.1 0.0 41.9 1.2 11.9 8.3 3.8 29.3 6.9 37.3 0.9 3.2 0.2 3.0 15.2 0.1 14.6 0.3 12.3 0.9 0.0 6.5 5.9 7.2 0.0 17.8 0.1 0.3 2.4 1.9 0.1 1.6 1.9 1.2 19.4 18.5 7.8 1.2 10.9 8.8 5.0 2.0 14.2 0.6 0.2 1.5 9.0 0.2 7.2 18.5 19.7 0.3 13.2 0.8 0.4 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.5 23.1 24.9 29.5 26.5 18.3 30.0 31.8 26.3 32.9 30.1 32.9 32.2 14.5 12.8 3.1 4.9 0.5 31.1 13.1 1.4 4.6 2.3 3.1 1.4 0.7 20.0 4.8 12.9 0.0 0.2 0.3 8.8 5.9 6.8 0.1 6.5 1.6 21.1 4.8 1.3 29.5 3.1 0.0 2.0 5.6 20.4 12.7 0.4 0.4 0.0 0.1 0.0 26.0 17.0 0.0 0.0 16.6 0.0 0.0 4.9 10.6 190.2 2.0 3.5 0.0 6.0 90.8 7.1 13.3 0.0 0.1 23.4 29.7 8.9 1.7 6.7 0.0 1.0 0.8 0.2 1.1 2.9 38.2 2.9 0.9 0.2 15.9 8.6 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported Microtubules,Cytosol NA NA 25000 "Cluster 13: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Microtubules Cytosol "HPA036687: AB_2675251, HPA036688: AB_10671968, HPA065337: AB_2685474" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "unprognostic (3.53e-3)" "unprognostic (1.79e-2)" "unprognostic (9.19e-2)" "unprognostic (8.61e-3)" "unprognostic (1.61e-2)" "unprognostic (2.96e-3)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 11.2 13.7 1.5 32.4 2.5 41.1 14.1 1.0 1.4 11.7 3.9 23.6 38.8 11.1 4.6 11.1 9.9 19.9 4.6 1.6 1.0 19.4 38.1 24.3 28.3 2.2 1.6 8.9 24.3 13.8 4.3 35.6 1.6 9.7 23.7 10.3 21.0 8.0 2.4 18.3 36.5 14.1 2.0 28.3 20.9 20.4 3.7 14.9 21.5 3.9 30.0 27.3 5.7 2.8 45.1 76.7 43.7 34.9 15.6 25.4 47.7 27.3 21.4 29.7 28.5 80.8 55.1 41.1 18.5 26.9 45.6 22.7 38.0 26.3 51.3 80.8 31.8 37.7 23.5 186.3 19.7 28.8 37.1 27.9 9.8 39.4 26.5 14.4 20.9 14.0 37.9 40.3 32.5 26.4 27.3 7.7 44.8 57.8 21.9 27.8 69.2 24.3 24.2 64.3 42.9 86.3 26.9 27.7 20.8 39.6 14.4 11.4 24.6 30.1 39.9 24.3 24.9 44.9 33.3 34.6 26.3 27.0 21.6 5.6 4.7 9.9 9.0 13.7 19.0 13.9 15.0 14.8 4.1 9.1 12.8 9.6 12.3 11.9 14.6 5.3 22.3 7.6 1.5 2.5 1.0 1.4 1.6 1.0 2.2 1.6 1.6 2.0 3.7 2.8 47.0 60.9 107.3 37.9 137.6 67.3 74.3 60.5 75.1 35.1 53.5 45.7 7.0 51.5 60.9 40.5 47.9 143.0 120.8 57.0 17.6 34.0 33.1 33.4 50.1 50.8 102.3 20.8 54.2 75.4 47.5 55.3 76.0 86.6 48.1 80.7 43.9 61.9 65.6 16.8 60.0 69.3 34.6 40.3 56.6 31.0 23.9 74.8 16.0 119.9 38.4 35.1 47.4 62.8 32.9 38.1 58.9 23.0 139.5 65.4 51.3 41.3 28.6 47.3 6.6 25.0 47.6 46.5 39.4 73.4 79.7 118.9 223.8 42.0 85.0 96.4 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 160.0;Glandular and luminal cells: 387.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Group enriched" "Detected in some" 18 "HEL: 4.4;Hep G2: 14.6;HMC-1: 6.2" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 1.2 6.2 0.4 1.1 0.4 0.1 6.6 0.9 0.5 32.1 0.2 9.3 16.2 3.8 1.2 0.5 2.3 1.3 0.1 0.3 0.5 10.0 5.0 0.9 0.5 0.5 0.6 0.5 0.1 0.3 0.1 0.1 0.5 2.4 8.4 0.3 18.1 15.6 0.1 0.6 44.5 0.8 0.4 0.3 0.5 0.8 0.5 9.6 0.3 0.2 0.4 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.4 0.0 14.6 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.5 0.3 0.5 0.5 0.6 0.5 0.4 0.5 0.4 0.4 0.0 1.1 5.2 0.2 0.0 2.6 0.7 1.2 0.2 1.0 0.6 0.3 0.0 2.5 0.0 0.0 0.0 0.2 9.2 1.9 0.0 1.6 160.0 46.3 1.4 0.0 2.1 2.1 0.0 0.1 0.5 0.0 387.2 36.0 0.1 0.7 1.7 0.1 0.0 4.1 1.5 0.0 0.6 1.1 0.4 1.2 1.5 1.8 2.8 0.0 0.1 1.0 3.5 0.9 0.0 1.9 0.7 0.3 2.7 53.3 9.1 5.4 0.1 0.0 0.2 1.0 2.5 0.8 0.0 0.6 0.1 2.2 0.1 4.9 1.1 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;kidney: 30.6;ovary: 12.5" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 119.9;Peritubular cells: 35.3;Proximal tubular cells: 31.3;Theca cells: 23.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.2;SH-SY5Y: 3.6;U-266/70: 2.9;U-266/84: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 290000 "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.2 0.3 2.7 0.8 11.8 0.9 0.8 14.2 5.5 0.2 2.3 1.0 1.7 0.2 6.1 1.0 0.3 0.5 0.2 2.7 6.1 30.6 0.1 0.3 0.9 20.4 9.6 12.5 0.0 0.0 4.2 0.1 18.1 2.2 1.0 0.1 0.7 6.1 0.2 0.1 2.2 0.1 12.5 1.0 1.2 2.4 11.1 1.9 0.1 1.3 2.8 0.6 0.3 29.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 2.7 11.8 14.2 5.5 2.7 6.1 20.4 9.6 18.1 12.5 11.1 29.4 0.5 0.0 0.0 5.9 0.1 0.0 0.2 0.9 0.6 0.0 0.1 0.5 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 3.9 1.1 1.0 0.0 0.0 0.5 0.0 0.0 4.3 0.2 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.4 0.2 0.0 1.5 0.0 0.0 0.6 0.0 0.4 4.1 0.6 1.8 4.7 1.1 0.0 0.0 6.6 119.9 0.0 0.0 35.3 0.5 0.1 0.0 31.3 0.2 0.0 0.0 5.1 0.6 0.1 1.6 0.0 0.0 0.0 0.3 23.9 0.0 0.3 EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 156.4;Inhibitory neurons: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "A549: 163.5;HaCaT: 237.9;OE19: 192.9;SK-BR-3: 185.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA054104: AB_2682380, HPA056817: AB_2683244" "unprognostic (2.01e-2)" "unprognostic (7.77e-2)" "unprognostic (1.76e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-2)" "unprognostic (3.87e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.30e-4)" "unprognostic (1.78e-1)" "prognostic favorable (4.39e-10)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.26e-2)" 55.1 122.1 68.6 8.1 73.8 0.4 25.7 66.0 97.2 37.7 0.0 31.2 13.8 27.9 31.0 46.3 45.3 40.3 21.3 64.7 81.7 64.7 8.9 30.1 4.4 101.5 80.3 41.8 29.3 37.0 21.1 21.8 94.0 26.9 20.9 39.5 56.6 42.6 12.0 14.2 16.7 27.2 53.0 8.1 64.2 18.3 75.0 4.5 24.8 15.4 14.0 40.7 31.7 79.9 53.5 163.5 57.7 21.5 36.8 22.8 53.8 16.8 37.7 35.1 27.9 108.7 93.7 3.0 26.4 52.7 71.7 237.9 26.7 19.6 26.2 0.5 14.9 0.4 52.7 107.6 11.3 0.2 19.4 19.9 9.4 32.9 2.7 44.7 8.6 13.0 2.7 41.5 30.5 34.2 1.8 0.9 21.4 192.9 49.9 2.6 16.0 66.3 30.5 84.6 20.1 24.5 74.9 185.6 6.4 43.9 45.8 2.4 7.3 40.9 43.0 20.8 3.7 50.3 19.0 0.6 71.2 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 68.6 73.8 66.0 97.2 64.7 81.7 101.5 80.3 94.0 53.0 75.0 79.9 14.5 16.0 22.1 27.7 0.4 2.9 5.0 11.1 30.7 31.9 12.8 9.4 8.5 28.6 16.5 47.8 156.4 1.5 0.8 23.8 19.6 22.2 2.9 10.6 8.7 9.2 15.5 0.0 56.8 10.8 0.5 11.0 50.4 7.5 52.5 13.3 10.0 3.7 6.9 32.0 75.7 6.0 4.1 1.3 2.2 2.7 15.8 6.0 3.6 3.7 0.0 22.7 0.0 24.6 73.1 31.6 15.7 42.2 2.1 5.1 8.0 37.1 21.9 8.7 32.9 6.8 35.1 4.6 7.1 43.2 1.7 1.1 0.8 7.1 13.2 18.0 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 36.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 13.7;Early spermatids: 14.1;Horizontal cells: 55.5;Late spermatids: 37.6;Rod photoreceptor cells: 40.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;K-562: 5.0;U-266/70: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074772: " "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.92e-5)" "unprognostic (5.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-4)" "unprognostic (4.40e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.9 0.3 0.6 6.6 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 36.5 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.1 2.4 1.2 0.9 0.1 0.0 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.2 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.2 2.3 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.3 0.6 1.5 1.2 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.4 5.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 13.7 0.0 14.1 0.0 0.0 0.8 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 2.0 0.0 0.0 0.0 0.0 37.6 0.0 0.1 0.0 3.7 0.0 4.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.3 0.0 0.1 0.8 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.6;parathyroid gland: 46.3;retina: 36.1;stomach 1: 35.1" "Group enriched" "Detected in many" 4 "Astrocytes: 330.7;Excitatory neurons: 415.2;Inhibitory neurons: 495.5;Oligodendrocyte precursor cells: 391.6;Oligodendrocytes: 218.7;Syncytiotrophoblasts: 214.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 23.0;SH-SY5Y: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044678: AB_10963215" "unprognostic (6.48e-2)" "unprognostic (1.11e-1)" "unprognostic (7.06e-2)" "unprognostic (7.32e-2)" "unprognostic (2.34e-1)" "unprognostic (5.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (2.88e-1)" "unprognostic (2.35e-1)" "unprognostic (1.79e-2)" "prognostic favorable (1.13e-11)" "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.65e-4)" "unprognostic (2.05e-1)" 0.4 6.4 1.1 0.2 3.1 0.0 3.6 16.9 12.3 1.5 7.4 0.5 5.3 0.4 0.9 1.6 2.5 0.7 10.6 4.4 2.3 29.0 0.7 0.5 0.2 45.4 4.9 0.7 5.7 46.3 1.5 10.6 49.6 3.1 0.3 36.1 16.0 0.7 5.8 0.8 5.0 0.2 1.6 1.1 35.1 1.1 3.5 0.6 5.9 10.2 0.3 0.7 0.2 6.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 23.0 3.4 2.5 8.1 42.4 0.0 0.4 0.0 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 3.1 16.9 12.3 4.4 2.3 45.4 4.9 49.6 1.6 3.5 6.1 0.2 0.0 1.8 330.7 0.2 0.3 3.8 0.6 0.6 29.5 9.5 5.2 51.2 10.0 1.8 23.9 58.4 35.4 0.0 0.0 54.8 5.0 5.1 15.9 2.0 1.3 8.3 0.0 415.2 2.4 4.7 3.0 70.3 3.5 0.0 0.5 1.1 0.6 4.8 48.8 495.5 1.7 14.2 0.3 0.4 8.1 0.3 0.5 8.8 36.5 0.0 13.3 0.0 391.6 218.7 0.4 1.3 0.7 0.1 4.9 16.3 29.0 16.0 41.3 0.0 10.3 0.4 1.6 0.3 0.8 0.3 214.9 0.3 1.1 2.6 1.7 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 137.7;Astrocytes: 67.3;Cardiomyocytes: 87.7;Enteroendocrine cells: 198.1;Excitatory neurons: 66.9;Oligodendrocyte precursor cells: 135.7" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 67.8;hTERT-RPE1: 76.2;SCLC-21H: 79.3;U-87 MG: 157.2;WM-115: 78.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" 4.9 23.0 13.6 1.9 10.9 0.2 8.2 119.9 12.1 2.3 0.1 4.1 2.2 4.4 2.3 2.7 1.5 17.3 35.6 14.6 5.6 3.2 3.9 28.7 1.4 4.6 14.0 1.4 3.1 11.5 7.4 3.5 9.0 5.5 4.3 4.5 91.6 12.6 0.8 1.9 3.5 3.5 3.1 9.1 2.6 8.9 32.8 4.7 12.2 2.5 1.9 2.7 1.5 8.1 0.1 4.9 35.5 67.8 12.1 35.4 0.1 3.2 12.1 2.0 8.0 0.0 16.6 0.0 3.6 5.6 9.8 0.4 1.5 3.8 4.3 0.9 1.6 2.1 3.1 0.0 7.1 12.3 4.5 10.7 0.0 23.3 1.9 76.2 15.3 1.1 11.0 0.6 14.6 0.0 0.1 0.0 53.2 2.1 36.5 0.0 21.5 2.9 23.7 0.4 79.3 15.6 0.0 1.2 19.6 12.2 1.2 0.5 8.6 7.0 2.2 13.8 13.4 12.2 4.1 0.0 157.2 0.8 78.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 10.9 119.9 12.1 14.6 5.6 4.6 14.0 9.0 3.1 32.8 8.1 16.0 19.2 137.7 67.3 0.0 1.0 2.8 0.9 13.6 4.9 5.8 23.6 87.7 28.6 0.7 3.7 0.0 0.6 0.1 0.8 5.9 3.6 25.4 1.3 3.9 11.1 198.1 0.8 66.9 0.9 0.4 17.7 1.1 2.0 2.5 0.2 2.9 13.1 3.4 5.0 45.3 2.4 0.0 7.2 1.6 8.7 1.5 0.7 12.4 28.1 0.0 12.6 0.0 135.7 4.3 0.9 0.1 34.6 1.2 0.6 0.0 3.0 1.4 0.6 19.7 17.4 12.6 1.2 2.1 3.1 1.3 0.3 2.2 9.7 1.2 0.3 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 EVC DWF-1 ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Microglial cells: 10.3;Skeletal myocytes: 10.5" "Cancer enhanced" "Detected in all" "renal cancer: 16.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 62.3;hTERT-HME1: 60.7;hTERT-RPE1: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008703, HPA016046" Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "HPA008703: AB_1078765, HPA016046: AB_1848299" "unprognostic (1.69e-1)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (9.37e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.63e-2)" "unprognostic (2.82e-1)" "prognostic favorable (5.60e-9)" "unprognostic (3.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (9.47e-5)" 6.6 3.3 2.2 3.0 2.4 0.1 5.4 1.5 1.4 10.3 4.4 8.4 1.9 13.7 8.3 8.1 13.9 14.1 7.2 1.6 2.1 26.0 2.8 8.3 2.8 3.7 2.4 33.5 9.3 18.8 1.9 3.6 1.7 11.4 3.4 1.7 9.6 9.8 1.4 7.8 3.0 11.7 2.5 3.0 4.6 3.5 2.7 4.2 9.4 3.3 2.8 7.0 6.0 1.3 7.5 9.4 5.1 13.4 32.6 46.7 1.8 16.3 62.3 18.6 23.9 0.0 0.0 0.0 5.1 26.2 31.0 8.7 5.4 13.5 15.2 12.4 3.7 0.0 5.6 2.5 24.1 0.0 1.4 23.2 19.4 24.8 60.7 53.0 13.1 0.0 0.1 0.1 43.6 0.0 0.0 0.0 5.6 0.0 8.6 11.4 14.1 0.2 6.4 1.3 2.9 8.7 0.0 0.0 6.4 4.9 3.4 0.6 22.9 15.8 3.0 11.3 14.5 9.9 8.6 0.8 45.2 0.0 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 1.5 1.4 1.6 2.1 3.7 2.4 1.7 2.5 2.7 1.3 0.5 3.2 2.3 26.4 0.1 3.4 1.9 3.6 2.2 0.5 0.5 1.1 2.0 1.5 2.2 3.7 0.0 0.1 0.0 0.0 1.9 0.6 0.5 0.8 6.6 0.7 0.0 0.4 1.2 0.0 0.0 6.5 1.5 4.5 0.0 1.5 0.7 0.8 0.0 0.0 1.1 0.0 2.0 0.0 1.0 0.2 0.9 0.2 5.4 10.3 0.0 2.0 0.0 2.0 0.1 0.3 0.0 0.7 0.4 0.9 0.0 1.5 1.5 0.1 0.0 10.5 2.6 0.0 0.0 2.0 2.8 0.1 0.9 2.4 0.0 1.2 EVI2A "EVDA, EVI2" ENSG00000126860 "Ecotropic viral integration site 2A" P22794 17 31316410-31321749 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;lymphoid tissue: 105.1" "Cell type enhanced" "Detected in many" "granulocytes: 81.4;Hofbauer cells: 114.2;Kupffer cells: 240.6;Langerhans cells: 112.5;Macrophages: 112.0;monocytes: 195.8;NK-cells: 87.6;Oligodendrocytes: 218.9;T-cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 57.1;Karpas-707: 99.1;RPMI-8226: 160.7" "Low region specificity" "Detected in all" "HPA045033, HPA057051" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nuclear bodies" "HPA045033: AB_2679191, HPA057051: AB_2683321" "unprognostic (7.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" "unprognostic (8.49e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.55e-4)" "unprognostic (1.90e-1)" "unprognostic (3.54e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.63e-6)" "unprognostic (7.64e-2)" "unprognostic (4.95e-2)" "unprognostic (5.87e-2)" "unprognostic (2.90e-2)" 10.9 7.9 72.3 47.9 106.9 31.2 8.1 98.9 126.4 8.1 53.3 11.3 11.0 3.6 1.4 6.0 2.8 17.9 4.2 73.2 82.1 2.9 9.6 20.1 53.6 105.0 89.1 2.4 2.8 2.3 1.4 21.0 109.1 3.8 13.6 0.9 4.0 3.2 0.9 1.9 12.2 7.1 88.3 38.2 12.8 1.8 83.3 105.1 2.5 3.7 40.8 20.3 2.8 155.7 0.1 0.1 0.0 0.0 4.9 30.0 0.1 4.1 6.6 5.0 17.3 0.0 1.5 26.2 0.0 5.3 29.0 0.1 0.0 0.3 14.3 0.0 0.2 0.1 0.1 0.1 57.1 31.5 33.4 37.6 0.0 7.2 20.0 7.7 1.8 24.7 1.1 99.1 39.4 0.6 22.9 35.3 0.0 0.0 0.0 23.8 3.9 160.7 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 34.5 11.6 21.5 0.6 0.9 14.8 44.2 0.0 30.1 17.1 23.0 18.1 6.0 91.0 3.6 36.0 44.6 44.0 28.5 51.0 42.6 62.4 14.7 60.4 53.8 177.1 32.4 35.8 20.4 60.9 95.1 72.3 106.9 98.9 126.4 73.2 82.1 105.0 89.1 109.1 88.3 83.3 155.7 1.2 0.0 5.6 1.3 48.3 4.0 0.4 0.4 0.0 0.3 0.7 0.9 0.7 0.0 1.3 0.0 0.0 0.7 68.7 0.1 0.0 0.2 2.8 0.3 0.5 2.7 0.0 8.8 0.8 0.0 0.8 2.2 4.1 0.9 81.4 0.0 6.1 1.6 114.2 0.0 0.8 0.1 2.0 240.6 112.5 1.6 0.3 112.0 14.2 9.4 195.8 0.5 87.6 1.0 218.9 0.0 0.0 0.0 53.6 0.3 0.0 0.6 1.6 1.0 0.0 0.7 1.2 0.2 0.3 0.4 3.1 1.4 116.0 0.1 0.6 0.4 EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 164.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.7;Microglial cells: 146.1;Oligodendrocyte precursor cells: 157.3;Rod photoreceptor cells: 177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" 8.7 14.4 5.9 8.2 7.5 12.9 8.0 7.7 8.6 6.5 8.0 9.6 8.1 6.1 5.7 4.2 5.8 10.1 7.1 8.2 6.0 6.4 10.1 10.7 9.5 3.4 2.4 3.9 10.0 6.3 6.1 37.4 3.7 8.6 10.2 164.2 5.6 4.3 31.8 5.0 9.5 7.7 3.3 9.1 7.0 9.9 6.1 8.5 28.4 19.7 8.2 10.1 3.5 7.1 19.8 24.3 25.7 16.8 1.3 1.6 9.1 9.0 24.9 8.1 9.7 9.1 16.5 22.5 19.0 4.3 6.6 12.3 20.8 5.7 10.1 20.1 20.9 35.1 8.3 11.7 9.6 36.4 30.6 2.2 3.0 7.2 4.8 14.6 113.8 14.6 29.2 14.5 4.0 10.7 15.3 23.2 3.5 40.2 7.0 22.5 11.2 11.6 17.4 13.2 8.5 11.9 9.2 9.2 11.8 6.4 18.2 18.8 22.4 0.6 8.2 7.5 14.7 10.8 12.4 18.1 2.8 41.6 9.3 6.2 4.9 15.2 3.0 3.9 3.0 6.7 3.4 2.8 5.1 6.6 2.7 3.2 30.6 2.8 3.9 11.1 3.3 2.4 5.9 7.5 7.7 8.6 8.2 6.0 3.4 2.4 3.7 3.3 6.1 7.1 28.3 16.0 16.7 33.6 27.6 3.3 10.7 8.6 3.4 40.2 9.8 6.5 12.0 20.0 15.0 16.5 39.6 22.9 24.1 14.3 5.9 28.3 5.4 8.8 3.0 53.1 25.6 39.2 181.7 15.4 7.8 7.8 13.7 16.5 10.8 24.3 77.1 14.2 21.4 23.5 100.3 16.6 14.2 18.2 12.5 12.6 4.4 18.9 5.4 146.1 22.8 27.1 19.6 157.3 84.7 14.1 10.3 14.7 13.8 14.1 10.8 8.4 10.0 177.8 13.1 13.6 9.0 25.0 25.5 4.9 4.8 20.5 18.4 29.8 11.9 15.8 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 204.7;BJ hTERT+: 244.1;fHDF/TERT166: 273.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 96000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: AB_2685931, HPA069104: AB_2686087, HPA069701: AB_2686175" "unprognostic (2.13e-3)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" "unprognostic (9.40e-3)" "unprognostic (6.77e-2)" "unprognostic (2.54e-1)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.63e-6)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (3.44e-3)" 28.4 48.1 7.9 23.6 11.8 2.0 20.2 7.8 9.2 48.4 23.7 34.6 22.9 29.2 17.8 35.1 19.5 36.4 23.7 9.9 11.4 11.8 54.2 21.2 8.9 13.7 12.5 41.5 25.6 22.4 18.5 35.6 11.2 35.5 33.7 3.1 61.2 27.8 16.6 15.6 24.4 61.7 9.0 8.8 34.4 12.5 12.1 4.3 17.6 22.7 19.5 35.6 26.4 13.4 43.5 30.7 18.5 21.9 197.4 204.7 6.1 167.9 244.1 69.7 105.8 8.1 33.0 0.0 23.0 273.8 118.8 11.9 0.1 53.7 80.1 0.2 4.6 3.1 30.3 40.6 70.6 0.1 5.8 122.1 17.0 101.2 23.3 157.2 101.4 0.1 3.4 0.2 102.9 11.0 0.1 2.3 3.8 18.3 15.6 0.8 90.9 3.2 23.4 8.7 0.7 9.4 33.8 0.7 33.8 42.8 20.8 3.8 156.3 75.4 34.8 95.3 39.5 0.7 0.2 0.3 123.3 3.3 63.0 0.6 3.2 0.0 0.1 3.6 0.0 0.4 0.1 0.1 2.6 0.1 0.1 0.1 2.4 0.0 1.4 0.3 0.0 0.9 7.9 11.8 7.8 9.2 9.9 11.4 13.7 12.5 11.2 9.0 12.1 13.4 28.1 16.0 13.2 5.9 2.2 12.2 47.4 43.7 15.4 0.3 29.9 21.2 17.2 14.3 56.0 7.3 0.0 2.2 0.2 46.8 9.8 45.6 1.0 17.5 88.6 35.2 15.7 3.6 1.0 61.0 47.0 94.9 35.7 39.1 1.3 30.4 31.1 68.3 16.1 0.0 1.8 78.7 83.4 7.2 15.0 6.3 110.9 8.7 21.4 17.8 6.4 12.2 0.0 14.6 31.0 47.6 41.6 116.2 8.5 92.6 39.0 11.7 47.8 1.2 19.7 49.4 44.3 1.2 5.5 23.6 10.2 3.4 3.1 94.1 32.0 82.7 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.4;Fibroblasts: 20.4;Langerhans cells: 11.9;Melanocytes: 5.4;Peritubular cells: 4.1;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" 6.5 0.1 0.8 0.0 2.0 0.1 5.2 5.9 1.7 0.4 5.1 0.6 0.0 0.2 0.0 0.1 0.4 0.4 0.7 0.6 0.8 0.0 0.0 0.2 0.0 1.9 1.3 0.1 0.1 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.1 0.0 1.0 6.3 0.2 0.1 1.3 0.1 0.5 0.5 1.6 0.7 4.3 2.9 0.1 0.4 0.2 2.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 5.9 1.7 0.6 0.8 1.9 1.3 1.5 1.3 1.6 2.6 0.8 0.0 0.0 1.0 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 20.4 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.9 0.3 2.5 0.3 5.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.0 0.0 FAM217B "C20orf177, dJ551D2.5" ENSG00000196227 "Family with sequence similarity 217 member B" Q9NTX9 20 59933764-59948680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041021, HPA056698" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA041021: AB_10959734, HPA056698: AB_2683212" "unprognostic (1.78e-1)" "unprognostic (2.92e-2)" "unprognostic (2.88e-2)" "unprognostic (1.32e-2)" "unprognostic (9.43e-2)" "unprognostic (5.05e-2)" "unprognostic (9.04e-8)" "unprognostic (2.78e-3)" "unprognostic (4.51e-2)" "unprognostic (1.56e-1)" "unprognostic (1.17e-1)" "unprognostic (9.89e-2)" "unprognostic (1.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (2.63e-2)" 4.8 4.0 8.6 6.3 10.3 13.6 4.9 5.7 17.3 4.8 0.1 4.2 5.1 6.8 5.6 4.6 5.5 4.1 9.9 10.8 6.7 5.3 2.0 5.3 9.3 6.1 6.9 10.7 3.0 3.8 6.9 6.3 6.4 7.5 3.5 8.2 4.3 9.0 15.5 3.5 5.9 4.5 5.9 6.3 4.6 9.5 7.4 9.4 6.8 17.4 8.8 3.6 3.1 12.1 9.1 6.1 14.0 9.6 6.6 9.8 11.2 12.7 10.8 13.8 9.9 31.9 19.4 20.0 21.0 5.3 11.1 21.9 15.2 10.6 13.4 11.1 9.6 18.7 15.5 18.5 4.2 30.2 24.3 5.7 12.9 10.2 3.3 5.6 4.1 23.8 13.6 8.2 9.0 16.6 53.0 16.4 13.6 8.5 12.5 12.7 13.8 19.5 5.3 14.1 14.2 16.9 17.0 21.8 18.9 12.9 21.2 21.1 5.8 11.4 13.3 11.8 6.8 14.0 25.7 23.9 15.8 19.4 7.6 9.3 5.9 8.2 8.5 3.7 10.3 4.9 8.0 7.7 6.5 5.7 8.2 8.8 11.1 8.0 3.6 5.2 7.6 6.0 8.6 10.3 5.7 17.3 10.8 6.7 6.1 6.9 6.4 5.9 7.4 12.1 16.0 16.0 19.4 25.5 18.5 5.4 5.4 13.6 10.2 35.6 16.4 16.0 34.9 10.0 12.1 11.0 22.9 23.4 22.2 11.7 17.6 5.5 29.9 8.4 15.5 16.7 8.4 11.3 33.5 8.2 12.0 18.0 7.1 6.6 29.1 19.3 17.2 5.0 19.1 60.6 32.6 5.3 8.2 34.0 13.4 24.9 17.4 13.2 12.4 12.2 32.4 24.4 44.3 22.6 27.9 8.1 5.1 10.1 16.8 9.6 26.3 14.5 17.5 32.0 32.9 36.2 16.6 52.4 16.2 11.0 5.4 6.8 23.3 13.1 9.5 9.7 FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403135-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 26: Non-specific - Mitochondria" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" Cytosol "HPA040930: AB_10795484, HPA041730: AB_10804114" "unprognostic (3.01e-2)" "unprognostic (6.44e-3)" "unprognostic (5.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.18e-1)" "unprognostic (8.10e-3)" "unprognostic (3.06e-1)" "unprognostic (2.15e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (8.51e-5)" "unprognostic (2.82e-2)" "unprognostic (8.91e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "prognostic favorable (5.53e-4)" 10.6 9.6 14.5 5.5 13.9 8.7 12.3 12.3 17.6 14.8 7.2 14.6 13.8 10.7 2.6 17.7 12.3 5.3 11.6 13.8 11.7 12.2 13.3 9.1 6.2 18.9 11.6 12.5 18.6 8.4 11.6 2.3 13.5 13.4 4.7 1.7 13.9 5.8 3.3 25.2 15.4 3.3 12.7 11.8 14.4 9.0 14.4 4.7 11.4 2.5 3.8 12.7 14.6 14.3 15.6 16.3 1.9 9.4 2.0 6.8 8.2 8.8 7.3 8.5 8.9 2.8 11.0 13.9 9.7 5.2 3.0 7.5 3.7 6.3 1.4 22.6 7.6 4.6 2.9 6.5 9.0 3.9 8.1 6.6 13.0 4.3 7.8 4.7 5.0 22.5 12.9 15.0 5.1 17.2 5.9 3.1 1.4 25.5 17.5 11.6 3.9 8.4 10.4 8.0 3.3 9.6 8.8 15.6 5.6 0.9 11.8 12.3 6.7 3.8 10.4 11.9 10.7 16.1 8.8 6.1 9.9 9.2 6.2 0.0 1.9 10.8 2.4 2.7 3.2 2.0 4.2 3.4 2.6 6.5 3.3 2.6 1.7 3.0 2.7 1.0 3.9 1.4 14.5 13.9 12.3 17.6 13.8 11.7 18.9 11.6 13.5 12.7 14.4 14.3 19.8 9.6 8.9 3.6 17.5 21.5 22.3 23.7 14.8 15.1 21.1 26.3 5.4 10.0 21.2 23.9 12.5 11.8 22.1 41.4 21.5 22.2 6.4 18.2 9.1 12.0 25.7 9.7 11.7 32.9 10.9 13.9 17.9 18.0 15.2 8.6 11.4 12.5 11.0 11.8 9.5 32.4 22.4 13.2 18.2 2.4 18.6 14.3 23.2 2.8 14.4 14.6 34.0 5.5 8.5 23.8 42.8 18.4 12.7 12.2 100.4 22.6 22.4 12.5 13.1 13.5 13.8 37.4 37.4 22.3 29.8 6.2 21.8 12.9 34.8 23.4 FAXDC2 "C5orf4, FLJ13758" ENSG00000170271 "Fatty acid hydroxylase domain containing 2" Q96IV6 5 154818492-154859252 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 304.9" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Erythroid cells: 93.5;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8;ASC TERT1: 26.3;HSkMC: 23.2;hTERT-RPE1: 25.3;SK-MEL-30: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (6.38e-3)" "unprognostic (2.88e-2)" "unprognostic (6.26e-2)" "unprognostic (5.11e-2)" "unprognostic (3.12e-2)" "unprognostic (2.70e-2)" "prognostic favorable (3.87e-5)" "unprognostic (8.29e-2)" "unprognostic (2.52e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (3.42e-2)" "prognostic favorable (9.71e-10)" "unprognostic (1.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.07e-3)" "unprognostic (3.94e-1)" 34.7 37.5 49.9 5.8 79.0 34.4 27.0 73.6 57.1 24.3 63.0 46.3 8.8 34.7 55.7 16.9 37.4 30.4 34.0 49.0 57.9 25.4 139.7 36.7 7.3 76.4 72.0 59.4 15.0 304.9 12.1 12.6 74.8 28.0 17.8 10.2 40.5 31.0 12.5 21.9 16.2 37.8 60.4 13.3 17.7 12.1 66.6 5.9 36.7 24.3 4.1 19.5 17.2 101.9 1.6 1.3 5.0 10.5 34.8 26.3 3.9 3.7 10.5 1.4 6.4 1.3 13.5 1.9 2.2 5.8 0.3 1.3 0.1 1.7 1.3 1.1 1.7 20.5 3.5 7.4 5.1 2.6 1.7 23.2 6.6 3.3 0.8 25.3 7.9 1.4 11.8 0.3 8.8 0.5 1.5 3.9 2.4 5.0 0.4 1.6 3.3 0.7 2.3 1.4 0.5 9.0 1.6 0.9 24.6 10.6 0.6 0.6 2.8 3.6 2.2 1.5 1.1 1.5 1.1 1.3 5.0 1.5 2.2 3.5 0.8 1.3 0.4 0.6 0.4 0.4 0.5 0.4 1.1 1.1 0.4 0.6 4.2 2.4 0.5 0.6 0.3 6.6 49.9 79.0 73.6 57.1 49.0 57.9 76.4 72.0 74.8 60.4 66.6 101.9 14.3 41.7 11.8 58.8 1.3 2.9 12.3 2.0 7.4 1.6 7.1 8.8 17.8 12.8 6.8 9.2 0.0 4.2 0.3 4.0 9.8 3.4 12.9 6.9 14.9 14.3 3.0 93.5 5.5 0.7 0.4 22.6 2.0 1.9 6.3 14.5 21.8 44.3 2.1 3.3 4.7 29.8 2.0 11.6 9.1 11.2 47.2 17.0 5.4 37.5 2.6 46.8 3.1 51.3 164.8 12.8 5.5 50.8 0.2 4.0 4.2 2.9 15.0 1.8 0.0 24.5 9.4 2.5 0.8 0.7 3.7 1.4 1.9 11.9 1.2 3.8 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 753.6;tongue: 385.3" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 11.2;Skeletal myocytes: 8.7;Spermatogonia: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Region enriched" "Detected in some" 4 "hippocampal formation: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.9;CACO-2: 2.1;HMC-1: 2.2;MCF7: 3.0;OE19: 2.9;PC-3: 2.0;SiHa: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 960000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 0.1 0.9 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.0 69.2 0.3 5.3 0.0 0.0 8.1 0.0 0.1 0.2 6.1 0.0 0.2 0.2 0.4 0.4 0.7 0.3 0.0 4.3 49.7 0.0 0.1 0.1 1.2 0.0 0.0 4.2 3.3 753.6 0.2 0.9 0.0 0.9 0.0 36.1 1.4 1.4 0.2 0.3 385.3 0.9 0.3 0.0 0.0 0.3 1.3 0.0 1.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 1.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 2.9 2.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 2.8 0.6 0.0 0.1 0.2 0.1 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.6 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 6.1 0.0 0.7 0.3 0.1 0.9 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.5 1.3 0.0 0.0 11.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.2 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 162.5" "Group enriched" "Detected in many" 4 "Kupffer cells: 466.3;Langerhans cells: 571.0;Macrophages: 430.3;monocytes: 463.1;Skeletal myocytes: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.5;eosinophil: 226.3;intermediate monocyte: 380.6;myeloid DC: 160.0;neutrophil: 294.7;non-classical monocyte: 379.8" "Group enriched" "Detected in all" 59 "dendritic cells: 160.0;granulocytes: 294.7;monocytes: 380.6" "Cell line enhanced" "Detected in some" "Karpas-707: 2.0;LHCN-M2: 2.9;NB-4: 2.9;RPTEC TERT1: 5.0;THP-1: 2.1;U-937: 5.0;WM-115: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" NA NA 38800000 7800000 "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "HPA021011: AB_1848532, HPA026682: AB_1848533" "unprognostic (9.80e-3)" "unprognostic (4.70e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (5.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" 48.5 24.4 3.3 89.4 2.7 5.8 35.1 5.3 3.5 17.2 6.1 44.9 43.7 17.8 7.6 38.5 22.1 45.4 21.6 2.4 5.4 44.9 43.5 32.7 56.5 7.7 5.9 10.9 8.3 5.2 7.9 21.6 6.7 10.5 57.2 0.8 14.8 11.7 8.8 13.9 69.8 45.7 6.2 162.5 23.5 6.2 3.9 30.1 18.8 24.6 27.5 73.3 7.1 9.8 0.0 0.0 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.9 0.0 0.0 2.9 0.1 0.0 0.0 0.1 0.2 0.3 5.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.0 5.7 2.8 256.5 226.3 3.9 380.6 1.2 4.3 2.5 3.4 160.0 2.0 1.8 3.0 294.7 2.5 379.8 6.2 4.7 174.0 3.3 2.7 5.3 3.5 2.4 5.4 7.7 5.9 6.7 6.2 3.9 9.8 102.0 6.4 12.1 0.0 26.2 38.1 1.1 0.1 3.4 1.1 1.4 3.0 4.4 0.0 5.0 88.3 10.4 1.3 60.3 17.3 5.9 1.9 7.5 2.6 0.7 50.6 0.0 7.0 0.3 0.0 1.4 102.8 2.0 5.0 10.1 0.6 45.3 5.2 36.2 1.7 0.4 0.3 0.0 466.3 571.0 9.4 27.7 430.3 49.8 33.7 463.1 13.6 39.1 0.0 0.9 0.1 10.9 19.5 82.6 1.1 42.5 5.9 2.2 7.4 0.0 166.2 8.2 0.4 0.4 2.1 31.3 3.7 24.1 0.2 0.8 1.5 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FITM1 FIT1 ENSG00000139914 "Fat storage inducing transmembrane protein 1" A5D6W6 14 24130659-24132849 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 171.1;skeletal muscle: 224.1" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 281.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.0;HMC-1: 1.2;RH-30: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA019842 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA019842: AB_1853025" "unprognostic (1.81e-2)" "unprognostic (4.29e-7)" "unprognostic (2.77e-1)" "unprognostic (2.02e-3)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "prognostic favorable (1.00e-3)" "unprognostic (1.20e-4)" "unprognostic (4.57e-1)" "unprognostic (2.12e-2)" "unprognostic (2.84e-2)" "unprognostic (3.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.86e-2)" "unprognostic (5.62e-1)" "unprognostic (1.96e-1)" "unprognostic (2.12e-3)" 1.0 7.3 0.7 0.2 0.8 1.7 1.2 1.1 1.1 0.9 0.6 1.3 0.9 0.8 0.5 1.3 0.8 0.2 171.1 0.6 0.7 1.8 27.0 1.4 0.5 0.8 0.7 1.4 15.5 0.1 1.5 0.1 0.8 3.3 0.3 0.8 7.4 0.4 224.1 1.6 2.3 0.0 0.6 10.2 1.3 2.2 0.7 0.4 2.0 1.7 0.2 0.7 0.9 1.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.1 0.2 2.0 0.2 0.0 1.2 0.2 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.3 0.2 0.2 0.2 0.6 0.0 0.0 0.3 0.3 2.0 0.0 0.1 0.3 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.2 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 1.1 1.1 0.6 0.7 0.8 0.7 0.8 0.6 0.7 1.0 2.7 0.0 0.0 0.0 0.6 0.1 0.3 0.4 0.0 1.8 1.3 0.9 281.6 1.5 0.2 0.0 0.0 0.2 1.1 1.9 0.0 1.0 2.2 0.5 0.3 5.0 1.2 0.0 0.3 3.0 0.2 12.2 1.1 0.9 0.0 0.6 1.1 37.4 0.2 0.0 0.2 1.1 0.0 0.8 0.3 3.9 0.0 0.4 0.0 0.0 0.9 0.9 2.1 0.0 0.4 0.8 0.3 0.7 0.2 0.3 3.8 0.6 0.3 0.7 0.0 56.8 7.5 1.5 0.3 0.7 0.6 0.7 0.8 12.3 0.9 0.2 FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 495.0" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 332.6;Karpas-707: 315.1;OE19: 527.2" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 25.6 17.6 4.0 60.2 4.1 34.5 34.5 3.7 4.9 42.4 5.6 57.2 70.8 17.4 86.4 16.2 19.1 25.4 13.1 3.8 12.0 13.8 59.4 23.9 55.4 5.7 6.3 13.8 495.0 4.7 47.2 15.6 5.2 28.9 53.3 2.1 160.2 32.7 2.4 8.0 55.9 26.2 3.8 76.4 70.6 6.1 9.6 16.4 22.9 0.4 77.4 49.2 17.3 4.8 13.6 24.7 3.0 4.5 116.0 141.3 3.8 123.2 183.3 128.0 154.5 78.3 88.3 192.8 2.2 226.8 1.1 60.6 31.6 60.4 77.0 39.1 7.7 6.6 24.7 0.3 332.6 3.2 3.3 165.0 109.8 99.2 171.4 67.2 75.4 53.1 3.0 315.1 49.9 44.7 26.3 5.1 7.4 527.2 33.9 76.5 3.3 280.7 21.0 2.3 35.0 10.6 36.6 66.5 24.4 4.0 2.0 7.0 49.2 21.0 2.8 2.1 2.3 132.3 122.2 108.1 16.1 3.9 33.0 6.0 1.0 2.8 115.7 1.3 188.3 50.5 80.5 92.7 1.9 25.7 38.8 69.9 4.1 26.7 1.1 39.3 33.4 36.3 4.0 4.1 3.7 4.9 3.8 12.0 5.7 6.3 5.2 3.8 9.6 4.8 22.3 16.0 19.1 5.2 229.8 28.3 56.0 48.6 39.3 5.5 45.0 43.3 2.3 30.0 42.8 9.2 39.6 21.5 130.9 23.1 7.9 23.7 18.4 19.2 117.8 32.3 25.1 20.6 5.3 171.7 80.7 64.1 31.6 31.0 12.7 34.0 40.4 96.6 10.9 1.7 3.7 227.7 16.2 15.1 26.1 17.4 27.7 10.1 272.1 0.0 8.0 1.8 158.6 1.5 1.8 59.8 14.3 13.9 1153.9 111.8 14.1 18.0 43.3 14.6 6.6 10.8 88.7 12.0 9.8 23.0 21.3 42.3 145.3 37.5 49.7 45.0 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FLVCR1 "AXPC1, FLVCR, MFSD7B, PCA, SLC49A1" ENSG00000162769 "FLVCR heme transporter 1" Q9Y5Y0 1 212858275-212899363 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Erythrocyte maturation, Transport" Receptor "Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "NTERA-2: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046646 Approved Approved "Cell Junctions" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "Cell Junctions" "HPA046646: AB_2679735" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.01e-1)" "unprognostic (2.83e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.03e-1)" "unprognostic (1.21e-1)" "unprognostic (3.88e-2)" "prognostic favorable (3.50e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.15e-2)" "unprognostic (2.25e-1)" "unprognostic (3.91e-2)" "unprognostic (7.29e-3)" 2.1 2.4 3.4 3.1 2.8 6.2 3.1 5.0 3.7 2.9 2.7 3.4 9.7 2.5 4.9 2.1 2.4 2.0 1.6 3.2 4.4 2.4 1.8 2.4 2.9 4.5 4.1 2.4 2.6 3.6 6.9 2.4 5.3 3.4 2.8 7.0 1.9 1.8 1.0 2.9 19.4 1.7 2.5 2.6 4.8 2.8 4.3 2.6 2.2 0.6 2.2 2.3 2.3 4.2 8.4 11.0 16.8 5.1 2.8 3.4 31.3 2.4 1.8 4.8 2.9 16.1 15.2 9.1 4.4 1.7 10.2 12.5 18.2 5.4 4.7 5.4 8.0 5.4 10.4 14.9 3.2 14.5 8.4 2.7 3.5 5.2 6.6 2.5 3.8 6.4 14.7 7.4 3.2 3.2 4.1 7.2 55.3 11.1 7.7 9.0 15.4 10.6 6.0 8.0 18.1 12.7 11.2 11.1 10.4 13.8 18.2 6.7 2.2 2.3 5.6 7.7 11.2 4.6 9.9 10.8 3.5 8.3 2.9 0.5 0.2 1.5 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.3 0.3 0.7 0.2 0.2 0.4 0.4 0.0 3.4 2.8 5.0 3.7 3.2 4.4 4.5 4.1 5.3 2.5 4.3 4.2 6.7 12.8 16.0 12.4 8.3 14.3 8.8 6.9 9.6 24.0 10.3 9.5 4.1 14.3 12.1 20.2 35.5 3.9 6.8 13.7 1.9 5.5 4.7 7.0 7.8 9.3 32.4 9.5 28.8 13.4 6.7 8.8 17.3 7.6 7.0 20.1 10.0 9.2 6.5 16.8 39.4 10.6 10.2 10.1 9.6 6.8 6.2 9.0 5.4 9.4 10.5 5.8 4.1 24.1 28.7 8.9 12.0 2.6 6.5 11.9 73.7 4.6 10.1 31.8 6.6 18.0 7.2 10.4 6.8 7.0 9.2 2.5 8.3 5.1 8.2 4.3 FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 199.0" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 97.9;Proximal tubular cells: 196.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 5.1 5.6 0.1 0.5 0.1 0.0 10.0 0.1 0.3 6.3 0.3 0.4 0.1 3.1 0.1 3.5 4.2 5.2 0.7 0.1 0.1 199.0 2.9 1.5 0.4 0.1 0.1 5.0 2.4 1.1 1.8 2.3 0.1 0.4 0.2 0.0 5.4 0.7 0.1 10.4 20.2 4.2 0.1 0.0 0.9 1.6 0.1 7.4 2.3 0.8 10.8 2.5 1.7 0.1 0.0 0.0 0.0 0.0 2.7 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.0 0.0 0.0 0.3 3.0 3.2 0.5 0.0 12.5 0.0 0.5 1.1 10.0 2.8 0.0 3.7 0.0 0.3 0.0 0.0 13.7 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.1 18.7 0.0 0.0 0.0 3.2 0.0 0.3 0.4 0.0 0.1 2.9 0.0 0.0 0.0 1.5 10.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 2.6 0.0 0.1 97.9 196.9 0.0 0.0 6.6 0.5 4.7 0.0 0.1 1.4 2.3 0.8 1.0 2.6 1.4 0.1 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.0;Hofbauer cells: 12.7;Kupffer cells: 18.8;Late spermatids: 26.8;Macrophages: 61.3;monocytes: 23.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Cell line enriched" "Detected in some" 20 "U-937: 32.7" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" 13.6 1.2 0.3 56.1 0.6 16.6 0.6 0.3 2.6 0.5 0.9 0.8 1.0 0.5 0.1 1.8 1.8 5.9 0.9 0.3 0.3 0.4 4.9 9.4 1.9 0.6 0.5 1.5 2.3 0.3 0.2 7.6 0.9 0.4 0.5 0.1 0.5 0.3 0.3 0.4 1.3 6.7 0.3 17.2 0.7 2.4 1.2 1.6 0.7 4.2 0.8 15.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.9 32.7 0.0 3.6 122.0 5.8 0.2 122.7 0.7 0.1 0.2 0.2 16.6 0.2 0.1 0.2 1187.9 0.2 85.0 3.3 0.1 46.0 0.3 0.6 0.3 2.6 0.3 0.3 0.6 0.5 0.9 0.3 1.2 0.5 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 9.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 5.1 0.0 0.4 0.4 12.7 0.0 0.0 0.0 0.0 18.8 0.8 26.8 0.0 61.3 0.0 0.0 23.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FSD2 "RP11-127F21, SPRYD1" ENSG00000186628 "Fibronectin type III and SPRY domain containing 2" A1L4K1 15 82755362-82806070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "heart muscle: 52.3;skeletal muscle: 154.3;tongue: 44.3" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 81.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 3.6;U-266/70: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046263 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA046263: AB_2679604" "unprognostic (2.80e-1)" "unprognostic (3.54e-1)" "unprognostic (6.63e-2)" "unprognostic (6.30e-2)" "unprognostic (7.71e-2)" "unprognostic (1.83e-1)" "unprognostic (5.97e-2)" "unprognostic (7.66e-2)" "unprognostic (1.07e-1)" "unprognostic (9.37e-2)" "unprognostic (3.05e-2)" "unprognostic (2.21e-1)" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-2)" "unprognostic (1.59e-2)" 0.2 0.7 0.2 0.9 0.2 0.8 0.1 0.7 0.4 0.0 0.0 0.1 0.9 0.4 0.6 1.9 0.3 0.3 52.3 0.3 0.5 0.3 0.1 0.2 1.1 0.1 0.1 0.6 0.6 0.7 0.1 0.3 0.2 1.2 0.0 2.4 0.8 0.0 154.3 1.5 0.8 0.1 0.0 0.6 0.6 0.7 0.3 0.0 0.9 44.3 0.1 0.1 0.0 0.6 0.7 0.7 1.1 1.3 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.6 1.2 2.3 0.5 0.0 0.6 2.8 0.0 0.0 0.2 0.4 3.1 1.3 3.6 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.1 0.7 0.0 1.0 1.2 2.0 0.0 0.7 0.4 1.4 1.0 0.5 0.6 0.8 0.8 0.6 0.1 1.3 1.1 0.9 0.5 0.5 0.9 0.5 0.9 1.0 0.5 1.6 0.8 0.6 1.0 4.7 2.1 0.8 1.0 2.8 0.4 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.7 0.4 0.3 0.5 0.1 0.1 0.2 0.0 0.3 0.6 0.4 0.0 2.2 1.3 0.2 0.4 1.0 0.2 0.0 2.1 0.5 0.3 81.6 1.5 0.8 0.0 6.2 0.1 0.3 0.1 0.0 0.0 4.8 1.7 0.3 1.2 1.2 0.0 3.9 0.4 0.1 3.0 0.0 1.6 1.3 0.6 0.0 0.0 0.3 11.8 3.6 0.0 2.0 0.3 2.1 6.1 0.3 0.2 0.0 1.0 0.1 0.7 0.0 4.0 3.3 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.5 4.5 0.0 4.5 0.6 0.6 0.3 0.0 0.6 0.3 0.4 0.2 0.1 0.3 FUBP1 "FBP, FUBP" ENSG00000162613 "Far upstream element binding protein 1" Q96AE4 1 77944055-77979110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006149 Supported Enhanced Nucleoplasm NA NA 300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA006149: AB_1849172" "unprognostic (4.17e-2)" "unprognostic (2.83e-2)" "unprognostic (3.35e-3)" "unprognostic (3.89e-2)" "unprognostic (3.77e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.83e-9)" "unprognostic (2.32e-2)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-3)" "unprognostic (9.80e-3)" "unprognostic (9.02e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (6.24e-2)" "unprognostic (9.46e-2)" 29.6 37.8 13.4 35.5 15.3 79.6 30.9 24.0 17.9 28.1 18.5 24.3 24.9 36.4 36.8 24.8 28.5 16.8 29.7 13.8 15.9 39.3 17.1 31.6 42.8 15.6 13.4 46.9 33.7 23.0 41.7 23.0 15.7 24.1 27.5 57.2 30.5 13.3 33.8 27.5 27.5 19.0 15.1 35.2 26.1 17.0 15.3 35.7 36.9 15.2 38.6 25.3 27.4 24.3 49.4 36.5 106.9 40.0 11.9 19.0 77.6 53.5 23.4 35.8 29.2 34.7 49.1 91.3 22.1 31.9 49.1 51.4 54.8 45.4 48.1 91.6 38.5 58.8 87.4 56.9 25.8 104.9 22.8 25.2 35.5 39.7 36.4 39.6 29.2 59.1 65.8 45.1 31.0 39.0 74.0 60.4 75.7 38.0 26.2 94.6 78.7 30.9 35.2 49.0 54.2 61.1 41.5 42.8 44.2 44.7 52.9 38.7 50.7 50.7 66.0 14.7 62.5 44.8 39.4 106.1 21.1 45.3 44.5 6.5 10.5 12.3 20.5 17.0 23.3 19.0 19.6 20.8 9.3 14.7 19.4 23.6 5.3 29.4 19.1 15.4 24.5 15.3 13.4 15.3 24.0 17.9 13.8 15.9 15.6 13.4 15.7 15.1 15.3 24.3 38.6 73.7 57.5 48.0 70.7 84.8 107.0 49.5 39.3 44.7 48.7 31.2 76.4 24.3 71.0 33.1 41.7 46.8 68.2 27.1 43.0 59.5 33.3 54.8 50.7 52.0 55.1 43.1 48.8 72.1 66.2 49.0 28.5 60.5 77.8 59.4 30.4 23.4 33.4 18.5 53.6 35.9 36.7 32.1 37.0 19.8 48.1 41.8 39.2 61.8 61.5 32.5 52.5 56.3 88.3 69.2 33.5 30.1 68.9 54.2 23.6 28.9 73.2 40.5 32.9 70.3 65.7 33.2 41.3 40.9 63.1 35.7 72.1 38.0 37.8 72.7 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 564.7;Hofbauer cells: 172.0;Proximal enterocytes: 690.7;Proximal tubular cells: 368.1" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 12.9 8.8 4.2 11.3 4.4 6.6 13.0 4.0 7.2 7.3 8.2 12.0 52.0 5.5 3.2 8.7 7.9 9.6 17.4 4.2 4.6 46.7 228.3 14.1 16.8 5.3 4.7 7.3 18.3 8.0 6.0 5.2 5.7 7.0 5.4 0.3 28.8 3.6 3.0 7.4 46.8 3.6 4.9 23.7 8.5 5.6 5.1 6.1 6.6 2.6 8.0 7.9 7.7 4.8 23.3 7.2 13.6 28.4 3.8 9.2 24.8 18.3 20.7 6.5 8.1 46.4 12.4 0.0 20.7 13.8 0.0 1.2 4.9 6.3 0.5 8.4 4.9 22.3 10.3 50.7 20.1 25.2 14.8 9.6 0.2 2.6 1.4 3.0 9.2 22.9 22.2 29.7 13.9 23.0 3.9 33.6 9.5 13.5 3.2 21.8 0.4 13.0 7.5 0.0 1.4 11.0 6.7 20.6 25.3 6.8 0.2 38.3 18.7 0.1 18.4 0.0 0.1 15.5 2.7 16.7 5.5 10.2 7.1 0.1 68.9 6.5 16.0 73.2 14.7 36.0 14.0 13.4 57.2 34.5 14.9 13.1 3.3 17.1 15.7 79.0 10.4 28.6 4.2 4.4 4.0 7.2 4.2 4.6 5.3 4.7 5.7 4.9 5.1 4.8 20.4 6.4 10.0 0.0 32.7 12.1 9.2 8.5 6.2 0.1 12.2 25.7 10.9 22.8 11.4 9.2 0.0 10.3 25.1 79.2 31.3 13.6 3.7 3.8 9.7 14.1 3.0 24.4 0.6 12.7 9.0 25.6 8.6 7.7 27.3 15.5 25.0 564.7 172.0 0.0 1.2 49.7 6.1 103.0 55.4 10.3 10.2 68.7 26.6 1.9 85.6 3.5 13.4 0.0 1.0 12.5 119.5 3.8 29.6 17.8 690.7 368.1 4.0 1.1 13.1 11.6 14.9 20.2 23.7 10.0 9.9 6.6 21.5 4.1 61.1 12.1 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 25.8;tongue: 11.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Club cells: 1.3;Collecting duct cells: 1.8;Fibroblasts: 5.9;Late spermatids: 1.8;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;TIME: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.3 0.4 2.2 0.4 2.1 1.2 0.4 2.6 2.5 0.1 0.1 0.2 0.2 0.3 0.6 0.6 0.2 0.3 0.6 1.8 0.8 0.7 0.3 0.3 0.4 0.9 0.5 0.6 0.4 0.2 0.2 0.3 0.9 0.6 0.2 1.7 0.4 0.1 25.8 0.9 0.2 0.2 0.1 0.6 0.3 0.5 1.0 0.1 0.9 11.3 0.3 0.2 0.0 2.3 0.4 0.0 0.2 0.4 0.3 0.1 0.5 0.2 0.1 0.0 0.0 0.5 0.5 0.4 0.2 0.0 0.2 0.3 4.7 0.1 0.1 0.6 0.1 0.5 0.8 0.2 0.0 0.3 1.3 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.5 1.7 0.2 0.3 0.2 0.5 0.5 0.1 0.1 0.7 0.9 0.4 0.2 0.6 0.5 0.3 0.2 0.3 1.3 0.3 0.4 0.3 2.4 0.6 0.5 0.8 0.2 0.6 0.3 0.3 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.2 2.1 2.6 2.5 1.8 0.8 0.9 0.5 0.9 0.1 1.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 1.8 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 65.2;Syncytiotrophoblasts: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 23.9 37.9 22.5 24.8 24.4 41.7 25.1 25.9 24.3 26.7 27.4 35.1 23.9 22.9 50.2 27.6 20.5 28.3 19.1 26.1 27.7 33.6 33.7 28.3 19.9 27.3 28.0 16.9 33.4 103.1 43.8 39.2 36.2 23.3 39.8 12.4 26.8 33.6 9.1 33.4 22.5 29.7 25.0 29.0 22.7 8.8 29.2 19.7 37.7 13.6 28.0 27.1 21.9 29.5 38.0 72.2 25.1 34.2 254.8 55.8 29.3 65.4 230.4 95.3 119.0 43.2 135.7 26.3 70.4 153.7 152.0 76.2 35.9 46.4 50.3 55.5 25.1 21.8 45.1 23.2 73.6 25.8 87.0 73.4 38.2 199.7 30.2 100.2 85.6 22.2 23.4 42.9 113.5 82.6 32.5 11.9 16.3 61.9 51.2 26.8 41.9 108.1 63.9 29.0 23.9 33.5 57.4 136.4 145.3 45.6 102.6 63.3 65.7 71.7 31.7 91.9 53.7 86.2 78.6 20.4 126.6 23.4 56.4 21.4 36.0 15.3 20.8 35.8 13.2 11.1 15.7 13.8 22.4 7.8 11.0 11.7 28.9 11.6 37.2 12.5 23.4 23.3 22.5 24.4 25.9 24.3 26.1 27.7 27.3 28.0 36.2 25.0 29.2 29.5 6.8 3.2 5.1 3.3 8.8 6.0 5.8 9.5 4.6 4.0 12.7 6.5 8.8 17.2 8.1 12.9 2.1 30.7 6.2 36.1 3.9 30.5 1.4 12.3 9.7 12.2 14.6 7.4 3.4 32.4 27.9 18.6 20.9 17.9 7.0 7.9 17.2 23.2 65.2 5.0 2.7 11.6 4.1 33.3 9.9 2.8 9.9 26.8 26.6 1.0 22.8 11.7 12.3 0.5 3.3 29.5 15.8 9.1 19.8 6.7 28.6 20.6 8.5 6.0 0.0 9.4 21.6 22.5 12.5 8.6 4.4 59.4 8.5 6.0 10.4 6.5 GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Hofbauer cells: 21.3;Kupffer cells: 31.9;Macrophages: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 64.1;HMC-1: 57.1;HUVEC TERT2: 24.0;NB-4: 29.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" 9.9 10.5 6.3 11.0 5.9 9.9 6.5 11.8 7.0 5.4 11.8 5.3 3.3 6.7 2.7 3.6 7.4 7.5 6.7 5.9 8.2 5.6 1.3 9.7 9.7 13.5 11.2 12.5 3.4 4.8 4.2 12.8 13.8 6.1 3.2 1.0 4.8 4.2 2.2 3.5 6.7 6.7 7.7 8.9 22.2 1.3 11.5 2.7 6.7 2.9 8.1 6.0 6.3 8.5 0.1 1.6 1.5 0.0 1.0 1.1 0.5 4.7 3.8 2.6 0.1 0.0 0.9 1.2 15.5 4.7 1.7 17.3 10.5 1.0 0.1 0.0 0.5 64.1 1.1 0.0 12.4 2.4 57.1 5.3 1.7 0.6 0.1 10.5 24.0 0.8 18.7 0.2 1.0 0.3 0.2 29.0 4.9 0.5 0.4 4.5 0.4 1.7 1.6 0.2 0.4 1.8 0.0 2.6 0.1 2.0 0.1 14.0 14.8 0.0 2.0 1.9 0.1 0.0 0.0 0.1 0.3 10.2 0.8 6.2 10.7 5.2 0.2 7.2 0.4 1.8 0.3 0.0 3.0 2.7 0.1 0.1 1.7 0.2 6.4 2.2 0.2 2.5 6.3 5.9 11.8 7.0 5.9 8.2 13.5 11.2 13.8 7.7 11.5 8.5 1.6 0.0 1.7 4.9 4.9 0.8 2.2 0.6 2.8 0.3 4.1 2.7 2.6 1.5 0.7 1.8 0.0 2.4 0.0 0.6 0.0 3.2 0.0 0.5 1.8 1.8 0.0 16.4 2.4 0.6 1.1 7.3 2.6 0.3 11.4 3.6 0.7 0.0 21.3 0.0 1.9 0.3 0.0 31.9 3.1 0.0 7.5 22.0 0.0 5.6 11.1 2.4 0.0 1.5 0.0 0.8 12.1 1.9 0.7 1.5 0.1 1.6 0.0 0.2 0.0 3.9 6.2 0.1 0.1 1.4 1.1 3.6 2.0 0.5 1.2 1.7 GBX1 ENSG00000164900 "Gastrulation brain homeobox 1" Q14549 7 151148589-151174745 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 12.9;testis: 5.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HMC-1: 1.5" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Low region specificity" "Detected in single" HPA055783 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA055783: AB_2682919" "unprognostic (4.24e-2)" "unprognostic (3.87e-2)" "unprognostic (3.58e-2)" "unprognostic (2.40e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.91e-1)" "unprognostic (3.14e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 1.4 0.0 0.0 5.2 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.7 0.2 0.9 1.1 0.0 0.0 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA031650: AB_10601014" "unprognostic (2.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (6.81e-5)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.69e-3)" "unprognostic (5.18e-2)" "prognostic favorable (2.00e-6)" "unprognostic (2.08e-1)" "unprognostic (7.93e-2)" "unprognostic (9.66e-2)" "unprognostic (4.02e-2)" 15.7 32.9 14.3 10.1 15.2 11.8 15.8 15.1 16.2 18.6 15.2 15.3 15.8 15.1 11.0 8.8 15.9 10.6 12.3 13.9 15.8 24.5 18.6 15.9 13.2 18.3 15.7 22.2 26.4 12.8 16.7 9.3 16.7 20.7 5.3 3.8 24.1 14.2 7.8 9.8 19.4 5.3 15.0 32.2 19.5 5.9 15.5 7.4 26.8 5.7 6.5 15.5 13.3 16.3 7.5 26.1 1.8 20.5 6.8 6.0 16.1 9.9 7.7 5.0 6.5 8.4 35.4 11.4 34.9 9.2 6.1 0.6 5.8 0.2 1.2 18.8 21.1 17.3 11.9 18.0 17.7 13.9 70.4 9.1 5.3 13.7 4.2 6.1 7.8 6.9 16.8 50.0 2.6 9.2 9.0 27.1 4.4 28.1 0.0 8.7 9.5 49.8 13.8 6.0 4.0 13.9 0.3 46.1 34.4 0.4 31.8 22.0 6.7 23.3 9.2 20.4 4.7 37.3 31.3 7.7 19.7 17.3 9.6 0.8 3.2 1.8 2.3 3.0 1.0 2.5 1.5 2.3 2.7 4.1 1.5 1.8 1.6 1.1 4.1 2.4 1.4 2.6 14.3 15.2 15.1 16.2 13.9 15.8 18.3 15.7 16.7 15.0 15.5 16.3 16.2 0.0 9.6 4.9 9.9 2.9 9.3 8.8 2.2 7.6 8.8 7.1 2.1 14.3 6.7 16.5 6.2 13.1 8.7 5.1 3.9 12.9 1.0 5.6 8.5 12.6 13.8 4.6 2.6 19.3 11.6 10.0 6.1 8.9 13.3 6.5 28.5 15.3 27.9 8.4 4.3 10.7 8.2 25.5 5.4 1.3 11.5 12.6 8.8 2.8 9.3 16.2 13.4 1.0 3.5 10.3 4.8 13.9 4.7 6.5 25.6 16.5 7.8 5.5 0.0 12.8 6.3 2.8 0.5 2.2 1.8 7.3 9.5 15.9 9.4 5.4 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-783390 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA021623: AB_1844365, HPA023246: AB_1844366, HPA023248: AB_1844367" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.11e-1)" "unprognostic (2.88e-1)" "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.86e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.18e-6)" "unprognostic (6.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" 42.5 46.8 27.4 33.5 31.0 22.5 34.5 25.4 33.3 28.4 33.4 71.3 80.5 31.6 33.6 42.9 44.9 32.6 37.3 30.6 36.4 75.7 67.7 31.5 46.9 27.8 27.9 39.9 40.5 37.6 23.2 36.7 28.8 37.8 48.3 25.6 39.5 27.3 39.8 44.3 72.7 31.9 28.3 36.8 85.3 19.4 35.3 35.2 47.4 23.0 40.0 41.5 22.4 27.5 121.1 106.8 120.9 67.1 52.0 51.5 73.8 94.4 57.6 75.0 56.7 87.4 84.0 142.9 100.2 42.8 69.7 85.5 106.6 60.1 78.0 105.4 91.2 69.0 55.7 115.5 51.6 72.1 87.5 36.2 81.9 75.5 66.0 47.7 70.4 116.9 115.1 90.4 80.2 73.9 124.1 55.3 88.7 118.8 36.3 122.7 49.0 65.9 74.5 81.2 54.8 91.8 74.8 53.6 124.6 75.3 66.6 75.2 92.2 71.0 56.8 99.9 120.4 50.3 100.0 89.1 83.6 79.5 75.9 26.1 51.8 48.7 68.1 64.1 73.2 70.0 81.0 82.2 45.9 75.4 68.9 75.7 7.1 64.0 70.4 47.2 99.1 75.9 27.4 31.0 25.4 33.3 30.6 36.4 27.8 27.9 28.8 28.3 35.3 27.5 52.2 57.7 35.2 11.4 48.5 47.9 40.4 91.1 40.5 39.6 39.2 36.3 30.9 54.3 70.4 101.2 29.2 104.5 43.2 39.3 178.1 77.3 34.0 44.0 34.3 43.8 28.9 54.7 12.7 57.4 85.9 41.5 71.4 40.8 40.4 42.1 31.1 58.8 82.3 13.5 13.6 52.0 97.6 30.1 26.5 63.3 38.8 40.8 67.6 7.5 61.7 39.8 44.3 10.1 13.2 58.7 52.0 46.6 27.5 39.4 110.5 186.1 66.8 38.7 46.0 30.3 45.8 23.5 32.9 53.6 54.8 69.1 53.3 57.2 63.7 39.3 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNB3 ENSG00000111664 "G protein subunit beta 3" P16520 12 6839954-6847393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "retina: 426.5" "Group enriched" "Detected in many" 7 "Bipolar cells: 471.3;Cone photoreceptor cells: 932.0;Rod photoreceptor cells: 462.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 14.1;NTERA-2: 17.0;U-698: 40.9" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.1" HPA040736 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (3.86e-2)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (2.53e-2)" "unprognostic (5.74e-3)" "unprognostic (5.98e-2)" "unprognostic (4.43e-3)" "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.25e-5)" "unprognostic (3.21e-2)" "unprognostic (4.77e-11)" "unprognostic (2.43e-1)" "unprognostic (6.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-2)" 0.9 1.4 6.3 1.6 6.0 1.0 0.6 6.7 9.5 2.3 6.7 1.4 1.7 2.2 0.7 0.4 1.6 1.1 4.4 5.9 6.6 2.0 0.2 0.7 1.6 5.7 5.3 2.8 0.7 1.5 36.2 0.4 5.6 2.1 0.6 426.5 2.1 1.4 1.3 0.7 1.5 3.2 5.2 0.9 1.0 0.6 5.7 0.3 1.6 0.3 1.6 1.6 1.1 6.4 0.4 1.2 9.4 3.1 1.3 2.0 0.9 4.8 0.8 2.5 2.1 1.9 0.5 14.1 0.1 5.1 0.1 0.5 9.2 0.3 2.3 1.2 2.1 3.4 6.8 1.5 0.9 1.1 2.3 2.4 0.5 2.4 2.7 9.6 2.5 1.8 1.5 1.3 1.2 0.7 0.7 0.8 17.0 0.1 0.5 0.7 2.8 0.9 0.5 0.4 1.1 2.2 0.4 0.1 1.0 2.5 0.1 0.6 4.0 3.2 3.8 4.8 6.7 1.4 1.0 40.9 1.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 6.0 6.7 9.5 5.9 6.6 5.7 5.3 5.6 5.2 5.7 6.4 0.3 0.0 0.0 5.2 1.3 0.4 0.4 0.2 1.2 471.3 0.8 1.3 6.1 0.0 0.1 0.0 932.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 3.3 0.0 1.3 12.3 0.0 0.0 2.3 2.0 0.1 0.0 0.1 1.1 0.0 0.1 74.0 12.4 0.0 4.1 0.3 0.4 0.0 3.7 0.1 1.8 3.7 0.1 86.7 0.0 6.0 1.2 0.1 0.0 3.4 3.2 0.8 0.0 0.1 0.6 462.8 0.0 0.3 1.4 0.1 0.5 0.0 0.0 0.0 0.4 0.2 0.1 0.2 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "B-cells: 23.6;Langerhans cells: 45.5;Macrophages: 30.2;monocytes: 19.1;NK-cells: 15.5;T-cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "HDLM-2: 26.9;Karpas-707: 26.6;THP-1: 8.2" "HPA029694, HPA029695" Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" 2.1 0.7 0.9 7.0 0.7 8.0 0.9 0.7 0.9 0.9 1.0 1.3 1.0 0.6 0.4 0.8 1.6 1.4 0.8 0.8 1.0 5.4 0.5 2.7 7.7 1.6 1.1 0.3 0.7 0.3 0.5 1.5 1.2 0.8 0.9 0.3 0.9 0.3 0.5 2.6 4.3 0.8 1.0 7.8 1.7 0.3 1.2 1.9 4.6 0.6 4.5 2.4 1.1 1.3 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.5 3.5 0.6 0.0 0.0 0.7 0.0 0.0 0.0 26.9 0.3 0.6 0.1 0.0 0.1 2.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 26.6 0.0 0.8 0.0 2.7 0.1 0.0 0.0 2.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 8.2 0.4 0.1 0.1 0.0 0.3 0.7 2.6 0.3 0.0 2.4 0.0 9.6 6.0 5.5 6.1 7.7 5.9 4.2 4.8 5.5 5.7 4.5 4.8 5.3 4.7 5.8 9.1 3.1 3.6 5.0 0.9 0.7 0.7 0.9 0.8 1.0 1.6 1.1 1.2 1.0 1.2 1.3 0.6 0.0 1.9 0.7 23.6 1.7 0.1 1.0 0.0 0.0 0.3 0.3 0.8 0.0 0.7 1.8 0.0 0.1 12.2 0.0 1.9 0.4 0.0 2.2 0.8 0.9 0.0 4.0 0.7 0.6 0.3 0.4 1.1 5.2 12.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.0 7.1 45.5 0.2 0.0 30.2 5.4 7.5 19.1 0.0 15.5 0.0 0.1 1.2 0.0 0.0 11.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 1.6 0.0 20.7 0.0 0.0 0.9 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.6;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in many" "dendritic cells: 256.1;granulocytes: 317.8;Kupffer cells: 112.5;monocytes: 90.9;NK-cells: 319.3;T-cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 5.7;HEL: 6.2;HL-60: 7.5;HMC-1: 9.0;RH-30: 11.5" "Not detected" "Not detected" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" 2.0 1.1 0.5 9.1 0.6 12.6 0.9 0.5 0.8 1.1 0.6 1.2 1.6 0.7 0.4 0.9 0.7 2.8 0.6 0.4 1.0 0.8 2.7 4.3 8.8 1.9 1.0 0.3 0.4 0.4 0.4 1.7 1.6 0.8 1.5 0.1 0.7 0.5 0.2 0.3 2.4 2.3 1.0 9.6 1.6 0.6 1.2 4.2 0.4 0.5 6.6 3.4 0.5 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.2 7.5 9.0 0.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 39.0 19.8 43.6 33.8 28.4 62.4 9.3 16.9 26.2 13.0 8.1 8.6 19.4 15.2 49.1 32.1 5.9 9.0 24.5 0.5 0.6 0.5 0.8 0.4 1.0 1.9 1.0 1.6 1.0 1.2 2.3 2.9 3.2 21.6 0.3 77.8 4.2 0.5 0.0 0.0 0.2 1.9 3.2 0.4 7.2 1.3 0.0 0.0 0.2 256.1 0.5 0.0 0.0 9.1 0.2 0.4 2.1 0.0 6.6 0.0 0.0 0.3 2.3 6.6 0.5 317.8 0.0 3.9 1.4 62.8 0.0 0.0 0.6 0.0 112.5 73.1 1.4 0.6 88.6 3.6 4.7 90.9 0.0 319.3 0.0 0.1 0.0 0.0 0.0 25.6 0.2 0.1 0.3 0.7 0.2 0.0 0.9 2.0 0.1 0.1 0.7 5.3 0.4 192.8 0.9 0.4 0.2 GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 78.7;Macrophages: 53.9;Sertoli cells: 78.9;T-cells: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 102.6;RPMI-8226: 27.7;SCLC-21H: 27.2;U-266/70: 15.9;U-266/84: 13.2" "Region enhanced" "Detected in many" "basal ganglia: 16.2" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA043148: AB_2678341, HPA057666: AB_2683496, HPA059092: AB_2683902" "unprognostic (9.05e-2)" "unprognostic (4.92e-2)" "prognostic favorable (7.22e-5)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-3)" "unprognostic (3.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.34e-3)" "unprognostic (3.13e-1)" "prognostic favorable (8.33e-4)" "unprognostic (1.91e-1)" "unprognostic (5.35e-2)" "unprognostic (3.93e-1)" "unprognostic (7.82e-4)" 2.7 1.2 4.1 9.0 9.5 7.8 1.4 17.8 3.1 2.2 0.9 5.3 6.2 1.4 0.7 0.9 0.9 3.5 4.0 2.2 7.3 3.9 2.0 6.9 10.2 4.3 6.5 3.2 5.1 0.6 2.9 1.0 4.5 0.8 7.1 3.5 1.5 0.6 1.0 0.6 5.3 1.4 4.1 7.1 3.6 0.4 5.0 2.8 1.3 3.2 7.9 2.7 1.0 5.9 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.8 0.1 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 102.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 27.7 0.3 0.1 27.2 0.6 0.0 0.1 1.1 1.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 15.9 13.2 0.1 0.5 0.0 0.0 0.0 0.3 0.0 2.8 1.0 3.8 0.2 2.7 2.2 0.9 0.0 1.1 1.1 0.0 1.9 1.5 0.0 3.4 1.0 4.1 9.5 17.8 3.1 2.2 7.3 4.3 6.5 4.5 4.1 5.0 5.9 11.1 0.0 22.6 10.1 6.7 1.1 0.9 0.1 0.0 12.2 1.6 1.7 20.3 8.6 5.0 3.7 0.0 0.2 51.2 17.4 1.9 2.0 0.2 5.8 3.4 11.7 78.7 6.5 21.7 9.4 0.1 3.0 15.8 15.0 7.6 12.2 1.8 0.4 18.7 26.9 32.7 38.0 0.0 28.2 29.0 0.0 0.3 53.9 1.8 41.2 7.4 1.0 23.7 26.2 0.5 1.3 11.0 1.2 48.6 0.3 16.3 1.9 0.7 10.8 78.9 3.3 32.7 0.1 0.8 0.3 1.0 0.3 76.9 0.7 26.2 0.5 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 237.3;Paneth cells: 88.4;Proximal enterocytes: 139.7;Proximal tubular cells: 164.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;Karpas-707: 2.8;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 22.6 2.4 2.2 4.6 1.9 2.3 12.5 3.3 4.7 0.7 3.5 36.0 18.3 0.5 0.4 2.4 1.3 2.4 40.3 2.1 0.4 13.9 179.6 0.4 0.3 0.8 0.5 1.1 10.3 1.4 2.9 0.1 0.6 1.8 5.8 0.6 14.6 1.2 50.1 17.1 18.0 0.4 0.2 0.6 15.0 2.6 0.9 0.0 0.9 24.3 0.2 0.6 1.3 0.9 0.2 0.8 0.2 0.5 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.9 0.4 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.7 1.3 0.3 1.5 2.5 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.2 2.8 0.0 1.3 0.4 0.4 0.3 0.6 0.5 0.5 0.1 1.5 0.0 0.9 0.5 0.8 0.2 0.7 0.1 0.1 1.9 0.1 0.2 0.1 0.6 0.7 0.1 2.9 0.2 0.2 0.4 0.9 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.2 1.9 3.3 4.7 2.1 0.4 0.8 0.5 0.6 0.2 0.9 0.9 0.2 0.0 0.0 14.4 5.3 1.7 1.3 1.2 0.6 0.9 14.1 4.6 8.5 34.3 1.8 7.3 0.0 0.0 0.4 176.9 21.5 1.1 16.5 0.5 0.4 1.1 2.4 43.2 0.8 2.4 3.3 0.3 51.0 0.7 8.9 0.3 14.3 237.3 0.1 3.3 0.5 30.4 0.0 14.4 2.1 48.1 0.6 1.2 1.8 1.0 0.1 15.6 0.0 2.0 0.0 1.3 88.4 0.4 0.1 1.2 139.7 164.9 0.5 2.0 0.0 2.0 0.4 1.0 0.6 2.4 4.5 0.0 1.8 0.4 62.1 1.6 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 209.8;Proximal enterocytes: 236.8;Proximal tubular cells: 162.7" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cell line enhanced" "Detected in some" "CACO-2: 14.0;Hep G2: 49.4;REH: 9.9;THP-1: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" 8.7 5.4 1.8 5.9 2.1 4.1 12.9 2.1 2.5 16.0 3.3 13.2 23.1 10.5 14.5 6.0 10.6 6.1 7.0 1.8 2.3 41.8 295.8 5.7 6.1 2.0 2.5 14.0 26.3 2.9 4.5 8.5 2.3 10.1 11.6 0.3 3.8 11.3 2.4 5.0 40.8 4.7 2.1 5.4 9.6 1.8 2.1 4.0 5.8 3.2 4.5 15.8 9.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 4.6 14.0 0.1 0.0 0.1 0.6 0.0 0.0 4.7 0.0 0.8 0.0 1.4 5.6 0.0 49.4 0.4 1.9 0.1 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 2.6 0.2 0.0 9.9 1.1 0.3 0.0 0.0 0.1 0.0 0.6 1.0 0.0 1.3 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 7.9 17.4 19.2 0.0 10.5 0.0 3.5 0.0 0.0 23.2 3.9 0.0 0.1 5.5 0.7 2.9 7.7 0.0 5.6 1.8 2.1 2.1 2.5 1.8 2.3 2.0 2.5 2.3 2.1 2.1 2.3 2.5 0.0 1.1 3.6 3.5 4.0 6.3 2.3 14.8 0.1 2.9 7.6 0.6 14.3 1.6 1.8 0.0 1.1 2.9 18.3 17.6 7.4 0.0 0.6 8.1 1.9 6.7 12.0 3.4 13.3 0.5 18.0 1.5 0.3 30.4 1.2 4.6 209.8 21.3 0.0 2.2 14.9 0.0 13.5 4.9 0.2 12.5 8.7 5.4 8.4 8.4 3.6 1.0 5.5 1.0 4.8 28.7 10.5 0.5 2.1 236.8 162.7 0.5 0.3 13.1 37.7 13.8 0.4 0.7 6.0 4.8 1.2 1.2 2.2 25.5 2.7 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 129.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "BEWO: 2.2;NB-4: 2.8;THP-1: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 1.4 0.3 0.1 2.9 0.1 11.5 2.2 0.1 0.4 0.8 0.1 0.5 0.6 0.4 0.0 1.0 0.7 0.6 0.3 0.1 0.1 0.3 198.2 2.3 0.5 0.1 0.1 0.2 0.9 0.1 3.0 0.4 0.1 0.2 0.4 0.0 0.6 0.1 0.2 61.1 0.8 0.5 0.0 7.6 0.4 0.1 0.1 0.5 0.2 0.6 1.4 0.5 1.4 0.2 0.4 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.4 0.4 0.0 0.6 0.3 0.2 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.1 2.8 0.9 0.1 0.4 0.2 0.1 0.0 0.1 0.6 0.1 0.3 0.3 0.0 0.0 0.0 0.0 11.4 0.1 0.1 0.1 0.1 0.1 0.4 0.5 0.1 0.0 1.7 0.0 56.9 15.1 2.4 0.0 5.7 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 73.3 0.7 13.6 0.3 0.2 4.4 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.7 2.8 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 3.2 2.0 0.4 0.0 9.7 0.2 0.2 0.7 0.1 0.5 15.0 0.0 0.1 2.5 129.6 0.3 0.0 0.1 0.1 0.0 7.7 0.8 0.0 0.0 3.5 0.0 0.0 6.3 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.4 0.2 1.2 0.7 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 2.8 0.0 0.6 0.0 0.3 0.1 HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "dendritic cells: 87.6;granulocytes: 80.6;Hofbauer cells: 148.3;Kupffer cells: 89.1;Langerhans cells: 67.8;Macrophages: 83.2;monocytes: 49.5;NK-cells: 70.0;Proximal tubular cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;Daudi: 6.4;HDLM-2: 26.3;HMC-1: 6.0;RPMI-8226: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" 14.2 8.2 9.5 19.7 11.1 13.9 5.3 11.1 13.3 4.9 10.4 5.4 4.0 3.2 6.0 3.7 3.3 12.8 2.5 9.1 11.8 26.8 9.8 22.6 32.1 18.0 13.7 1.7 3.0 2.8 1.8 16.9 16.9 2.1 6.8 1.2 2.9 2.9 1.7 2.2 4.9 7.9 16.1 24.1 4.7 2.0 17.5 9.1 1.6 2.1 14.0 13.1 1.2 27.2 0.0 0.2 0.1 0.2 7.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 6.4 0.3 0.0 0.2 0.1 0.0 0.0 0.0 26.3 0.0 1.1 0.1 0.0 0.0 0.0 6.0 0.4 0.4 0.0 0.2 0.0 0.0 0.7 0.1 2.3 0.0 0.1 0.1 3.9 0.2 0.0 0.0 0.1 3.0 21.5 0.3 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.2 0.3 0.0 0.9 0.3 0.3 0.0 0.3 1.8 0.2 0.1 0.7 0.1 16.7 53.8 0.1 14.6 57.9 3.0 1.2 5.9 7.9 137.9 0.5 7.0 9.5 2.5 97.1 36.1 16.4 11.5 43.1 9.5 11.1 11.1 13.3 9.1 11.8 18.0 13.7 16.9 16.1 17.5 27.2 1.2 6.4 6.5 2.0 5.9 1.0 0.2 0.1 0.0 0.9 0.7 1.5 1.1 0.0 1.9 0.0 0.0 0.6 87.6 0.3 7.9 0.1 11.1 0.1 0.1 3.7 0.0 1.3 2.1 0.0 0.8 0.9 0.5 0.1 80.6 0.1 1.1 0.5 148.3 0.0 1.7 0.3 0.0 89.1 67.8 7.8 0.3 83.2 3.6 31.9 49.5 0.1 70.0 1.0 4.8 0.1 0.1 0.0 16.3 0.5 0.1 57.7 0.0 0.2 6.6 0.7 0.5 0.3 0.4 0.1 1.3 1.1 26.3 1.5 0.2 0.3 HCFC1R1 "FLJ20568, HPIP" ENSG00000103145 "Host cell factor C1 regulator 1" Q9NWW0 16 3022625-3024286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 511.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 396.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 376.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059647 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA059647: AB_2684094" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.85e-3)" "unprognostic (6.03e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (1.61e-2)" "unprognostic (2.12e-1)" "unprognostic (3.43e-3)" "unprognostic (2.23e-1)" "unprognostic (2.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (4.89e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" 82.6 98.5 174.5 20.9 178.9 17.9 74.8 164.1 248.1 124.9 129.3 131.5 30.4 140.6 29.2 59.0 81.7 43.1 138.7 172.0 182.0 180.5 48.2 72.0 24.2 181.5 182.7 86.7 44.0 40.9 97.7 32.1 185.2 102.8 18.8 21.6 50.6 87.4 511.6 76.3 53.1 47.5 154.0 45.9 65.6 36.6 181.0 17.0 68.0 196.2 18.3 85.2 103.0 174.1 59.6 175.6 32.5 38.1 123.0 160.9 33.4 26.0 115.0 57.8 161.2 37.9 75.8 49.2 66.1 108.3 52.8 81.0 32.7 121.5 26.3 62.7 88.4 21.3 132.2 65.5 105.2 37.3 39.5 205.7 73.9 62.1 63.4 376.5 81.5 33.0 30.4 81.6 63.3 63.0 20.1 53.0 70.5 34.7 36.5 70.1 31.3 124.6 209.4 13.7 57.3 48.4 54.7 70.7 78.5 77.5 48.6 28.1 35.5 98.4 256.8 85.8 50.7 53.0 59.1 40.7 42.9 22.1 23.8 5.3 36.3 16.3 20.1 28.2 19.3 23.2 25.5 21.7 44.9 21.7 18.5 22.9 8.0 25.8 26.5 22.1 36.7 17.9 174.5 178.9 164.1 248.1 172.0 182.0 181.5 182.7 185.2 154.0 181.0 174.1 51.3 57.7 15.0 17.9 30.7 85.4 58.0 123.7 92.2 29.3 45.2 80.0 45.8 47.1 37.4 198.6 6.2 116.2 23.7 53.7 240.7 49.7 5.2 38.0 56.0 38.3 43.7 37.0 19.3 26.5 120.7 98.4 34.1 45.3 40.0 26.1 60.3 45.9 117.9 20.2 19.8 40.9 40.7 57.5 57.0 15.8 96.3 42.2 64.0 13.1 51.0 52.6 39.1 6.6 19.0 26.7 55.4 178.3 35.0 37.8 114.2 396.2 28.4 28.1 124.9 39.7 149.2 15.2 44.3 69.5 65.8 53.9 35.0 26.7 45.9 41.3 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HCN1 "BCNG-1, BCNG1, HAC-2" ENSG00000164588 "Hyperpolarization activated cyclic nucleotide gated potassium channel 1" O60741 5 45254948-45696498 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 7.2;retina: 17.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 671.7;Inhibitory neurons: 766.5;Rod photoreceptor cells: 199.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019195 Enhanced NA NA "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019195: AB_2670094" "unprognostic (1.30e-1)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (6.82e-2)" "unprognostic (1.10e-1)" "unprognostic (9.63e-3)" "unprognostic (4.11e-3)" "unprognostic (6.78e-2)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (3.68e-3)" 0.0 0.4 1.8 0.0 2.5 0.1 0.0 2.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.5 2.4 7.2 2.5 1.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 24.5 0.0 0.1 0.1 0.0 0.0 29.4 0.0 0.0 7.4 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 671.7 0.7 0.0 0.6 0.0 0.1 0.0 0.6 0.0 0.0 0.0 6.7 766.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.5 0.0 14.8 0.0 21.1 14.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 199.4 0.0 0.3 0.1 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HERC5 CEB1 ENSG00000138646 "HECT and RLD domain containing E3 ubiquitin protein ligase 5" Q9UII4 4 88457119-88506163 "Predicted membrane proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.9" "Cell type enhanced" "Detected in many" "Early spermatids: 90.5;Spermatocytes: 272.1;Spermatogonia: 431.3" "Cancer enriched" "Detected in all" 5 "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 89.9;BJ hTERT+ SV40 Large T+ RasG12V: 123.5;SK-MEL-30: 58.1" "Low region specificity" "Detected in all" HPA043929 Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA043929: AB_10962492" "unprognostic (2.87e-1)" "unprognostic (2.10e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (4.46e-5)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.35e-1)" "unprognostic (2.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.23e-2)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (1.61e-1)" 5.5 6.0 3.1 6.0 3.8 18.8 4.9 2.7 5.1 7.8 4.8 3.9 4.0 15.4 3.3 2.6 5.9 5.8 4.0 2.8 3.0 6.4 9.7 6.5 7.2 4.5 4.0 14.0 7.7 9.6 4.1 10.2 4.1 5.5 2.6 3.7 11.9 5.8 1.5 2.5 4.6 13.4 5.6 12.1 4.8 57.9 3.1 13.9 5.3 3.4 4.3 4.5 4.4 4.6 7.5 3.5 2.0 0.4 0.4 0.8 27.9 0.6 10.7 89.9 123.5 1.1 19.9 0.3 4.9 0.0 40.8 1.4 13.7 2.1 7.6 46.4 8.4 12.1 13.2 0.3 0.8 14.8 5.5 0.8 0.6 22.7 0.0 4.9 0.6 24.4 0.5 28.2 1.7 0.8 45.9 18.2 7.5 0.4 2.4 45.3 35.9 1.9 1.6 1.7 0.5 11.7 15.0 0.3 58.1 23.3 1.2 8.2 0.3 1.1 0.2 0.5 5.9 38.7 36.3 0.3 8.6 10.9 1.1 14.8 7.2 11.6 7.6 8.4 8.6 7.1 8.7 6.3 2.7 4.4 5.4 4.7 25.1 8.0 7.9 8.0 27.7 5.0 3.1 3.8 2.7 5.1 2.8 3.0 4.5 4.0 4.1 5.6 3.1 4.6 26.9 0.0 0.5 5.5 14.8 4.0 5.9 0.8 8.0 7.9 6.4 7.1 2.3 2.8 1.0 1.8 18.8 25.8 19.9 1.1 23.5 2.6 90.5 5.4 2.0 20.6 0.0 3.8 0.4 5.1 12.1 10.9 3.6 3.9 2.5 57.1 14.3 7.8 15.0 0.0 1.1 0.7 0.0 8.1 2.5 19.4 9.9 16.6 7.2 7.5 8.3 9.6 16.5 18.1 1.8 2.8 2.3 9.1 34.5 7.3 2.6 9.8 1.7 2.8 19.7 10.8 7.9 272.1 431.3 2.5 1.8 11.9 19.2 20.2 0.4 1.7 HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 39.2;T-47d: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" 9.6 7.9 1.3 5.3 2.1 0.6 7.8 1.4 1.9 6.7 9.3 5.8 5.9 4.9 12.4 4.8 4.5 8.1 3.7 1.5 1.5 6.7 15.4 7.5 3.6 2.4 1.7 7.3 6.3 15.4 1.2 6.1 2.2 6.8 6.9 1.3 6.9 9.6 2.3 2.8 5.0 6.0 1.7 8.6 8.3 1.7 1.9 1.7 9.9 3.0 3.1 7.4 3.2 2.8 17.2 39.2 0.7 18.6 27.3 21.1 0.1 12.2 28.5 15.1 23.6 3.3 34.3 1.8 32.4 20.2 22.9 10.7 0.0 14.2 19.1 4.6 0.2 0.5 8.1 2.6 5.6 0.0 0.7 21.6 4.0 16.7 1.4 13.2 10.4 0.0 0.7 0.4 13.0 7.2 0.1 0.2 0.9 8.1 0.0 2.3 0.0 0.3 12.5 11.5 0.1 0.1 7.3 0.0 10.2 0.3 54.0 1.9 8.2 10.6 1.1 10.7 10.6 0.2 0.4 0.2 15.9 0.2 23.5 1.3 10.7 0.0 1.5 10.4 1.2 3.3 1.6 2.1 4.7 1.3 0.4 1.0 1.9 0.2 9.2 0.3 0.3 3.8 1.3 2.1 1.4 1.9 1.5 1.5 2.4 1.7 2.2 1.7 1.9 2.8 3.9 3.2 5.1 1.0 1.7 1.7 2.6 3.7 6.2 1.0 3.7 2.2 3.2 2.8 6.7 5.5 2.1 1.7 0.5 3.8 0.0 4.1 0.1 1.8 2.3 3.4 1.8 2.7 0.1 3.4 0.8 4.6 8.2 1.5 2.5 3.0 6.8 12.2 11.1 0.0 0.1 4.0 4.1 25.4 7.6 0.2 3.7 7.4 0.0 2.8 3.8 2.9 2.1 0.0 3.3 2.4 0.9 6.0 0.3 2.6 2.9 2.7 5.9 1.7 0.0 5.7 2.4 0.2 1.1 3.4 3.4 1.8 1.0 2.8 3.3 1.9 HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.8;Excitatory neurons: 47.7;Microglial cells: 20.6;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 13.6;LHCN-M2: 11.6;RH-30: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" 2.1 6.5 1.1 0.6 1.1 0.4 3.3 0.3 1.6 3.4 3.6 2.3 1.1 2.5 3.1 2.8 2.8 2.2 2.4 1.0 0.4 4.0 2.7 2.1 0.8 0.7 0.8 2.1 2.3 1.7 3.2 1.3 0.6 4.0 1.3 1.7 4.4 2.0 0.3 3.4 2.5 1.1 0.9 2.2 1.8 2.5 0.6 2.0 4.6 0.2 0.8 3.1 2.9 0.9 0.8 0.9 2.3 1.3 1.0 1.3 4.8 1.2 1.1 1.9 3.1 0.2 0.9 0.0 1.2 0.9 3.1 0.6 0.5 0.5 2.2 1.7 1.2 0.0 0.1 1.1 0.2 0.3 13.6 1.2 2.7 1.6 1.2 3.2 0.3 1.2 0.0 0.0 11.6 1.2 0.6 0.0 0.6 0.7 0.1 1.3 12.4 0.0 7.5 2.6 1.9 7.8 2.1 0.0 6.0 5.9 4.0 0.7 1.7 2.8 8.5 1.6 4.7 3.8 0.2 0.0 1.1 0.8 2.3 0.0 0.3 0.0 0.7 0.4 1.3 1.5 0.9 0.8 0.4 1.8 0.0 0.2 0.0 0.1 0.1 3.7 0.2 0.4 1.1 1.1 0.3 1.6 1.0 0.4 0.7 0.8 0.6 0.9 0.6 0.9 2.0 0.0 2.4 25.8 5.3 2.2 5.7 2.8 6.8 0.5 5.8 2.4 2.4 4.3 1.2 9.2 0.0 4.6 13.9 1.9 3.9 2.6 1.2 8.8 2.6 2.0 0.0 0.4 47.7 0.7 3.6 3.0 2.6 5.8 0.0 4.6 3.6 2.5 1.9 0.0 11.8 2.7 4.1 2.9 0.5 0.5 1.2 1.5 0.0 20.6 1.0 15.6 0.0 17.1 26.0 1.2 2.1 0.4 2.2 3.7 2.3 0.6 12.9 0.5 0.0 1.7 1.7 0.3 1.3 3.1 2.6 2.2 2.8 0.4 2.0 5.2 HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 77.2;Cholangiocytes: 125.8;dendritic cells: 57.6;Ductal cells: 107.9;Endothelial cells: 80.0;Hepatic stellate cells: 88.9;Hepatocytes: 58.3;Hofbauer cells: 72.6;Kupffer cells: 63.5" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 87.7;HEL: 99.9;HMC-1: 105.6;HUVEC TERT2: 106.1;K-562: 154.8;NB-4: 101.8;U-937: 79.7" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" 16.2 18.5 5.0 22.2 5.4 84.7 11.2 5.6 8.8 7.1 5.1 7.8 6.4 6.4 3.5 4.1 6.1 27.4 6.1 4.8 5.2 7.0 91.2 16.9 39.1 6.3 5.4 3.0 38.1 1.9 2.2 14.6 6.4 4.7 6.5 0.3 3.5 4.0 2.9 4.6 19.0 5.8 6.2 39.9 5.2 2.4 6.0 4.4 102.1 6.3 30.4 12.7 5.0 6.7 11.2 20.6 10.5 0.1 0.9 0.7 0.2 5.6 46.4 7.4 6.6 4.0 2.6 10.7 87.7 0.7 0.0 2.1 9.5 0.3 9.1 0.1 11.1 99.9 8.8 67.4 21.0 58.6 105.6 0.3 0.2 6.5 0.0 3.7 106.1 0.3 154.8 0.1 0.5 3.2 0.4 101.8 0.2 30.2 11.8 34.0 3.0 0.1 0.9 4.3 4.9 1.0 6.2 0.0 0.1 0.5 3.3 30.6 37.2 0.0 0.6 0.1 0.1 2.6 1.8 21.2 0.0 79.7 51.4 28.0 41.5 61.8 0.8 45.7 0.3 59.3 0.0 0.1 30.8 65.8 0.1 0.1 31.4 1.0 50.7 36.3 0.4 15.5 5.0 5.4 5.6 8.8 4.8 5.2 6.3 5.4 6.4 6.2 6.0 6.7 31.9 0.0 3.0 0.0 77.2 6.4 2.1 0.9 2.2 0.0 3.0 3.2 3.6 125.8 1.6 0.0 0.0 0.7 57.6 0.4 0.0 107.9 0.3 0.8 0.5 80.0 5.3 28.2 0.0 12.0 0.7 2.2 0.5 1.0 7.0 0.0 88.9 58.3 72.6 0.0 0.0 1.6 0.0 63.5 29.1 1.1 0.3 51.7 7.2 5.6 50.4 0.0 9.2 0.5 0.0 10.5 0.0 1.2 1.6 3.2 0.0 0.2 0.9 0.2 0.0 1.9 2.1 0.3 6.3 1.0 3.7 1.1 8.3 3.4 0.7 1.3 HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 175.6;Leydig cells: 136.1;Oligodendrocytes: 413.3;Theca cells: 162.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 322.6;TIME: 376.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" 2.3 2.3 10.4 0.4 25.4 0.8 0.3 10.7 19.6 1.3 0.0 3.2 2.6 1.6 3.8 0.0 0.1 1.1 0.2 17.1 11.0 0.8 6.8 16.2 0.0 20.0 20.2 0.6 2.6 0.0 0.3 0.0 13.6 4.7 3.2 0.9 0.3 2.6 0.4 0.2 3.7 0.1 9.4 0.0 5.9 1.5 18.1 2.7 0.6 1.3 0.0 5.0 0.3 37.3 0.0 0.1 4.9 0.1 0.3 1.9 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.2 0.3 0.0 2.2 0.0 2.0 0.1 0.0 0.1 0.1 0.0 0.0 10.4 7.8 17.2 322.6 29.1 0.1 0.0 4.8 0.0 47.7 0.0 4.4 0.0 2.8 0.4 65.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 376.7 0.4 3.9 0.3 2.5 2.2 0.0 10.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.4 25.4 10.7 19.6 17.1 11.0 20.0 20.2 13.6 9.4 18.1 37.3 0.3 12.8 175.6 3.9 0.4 0.0 0.0 0.5 0.0 42.7 0.0 0.0 1.2 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.5 6.0 0.6 0.0 0.0 17.6 0.4 0.0 38.9 0.0 0.4 16.5 0.1 9.3 0.1 0.1 0.0 13.9 0.0 2.0 0.0 0.4 4.5 136.1 1.3 1.8 1.0 0.0 0.3 0.0 8.5 413.3 0.1 0.0 44.0 0.0 0.0 0.0 0.0 4.4 3.3 0.0 1.7 0.9 0.3 0.5 0.0 0.6 0.0 1.0 162.7 0.0 0.0 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 230.2;Proximal tubular cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 34.0 60.1 40.6 17.4 49.2 14.5 28.5 40.5 60.3 33.4 51.0 37.5 55.9 28.1 29.1 34.9 22.5 22.3 28.7 40.7 47.7 142.2 129.0 13.9 20.5 43.9 43.1 18.6 27.2 58.2 19.1 18.6 44.9 25.5 40.9 38.4 20.9 23.2 49.2 58.7 33.9 18.3 45.0 17.8 25.6 21.7 43.3 16.8 31.7 38.5 21.9 23.7 26.6 72.6 23.5 16.1 37.0 23.8 29.9 27.6 16.9 23.1 11.4 20.8 22.1 46.8 20.2 33.3 36.1 18.1 17.0 44.4 33.2 30.7 29.5 47.0 25.1 44.5 37.7 41.4 10.7 31.8 16.7 19.8 17.8 24.3 4.8 32.3 31.6 30.4 55.2 30.3 20.8 18.2 34.3 33.6 11.1 30.2 30.2 42.4 24.8 83.8 43.8 68.4 27.9 24.0 18.0 27.2 66.8 47.2 32.0 21.3 26.5 22.8 20.8 16.1 15.8 18.7 45.2 30.9 20.7 27.4 18.6 27.8 11.9 26.4 19.5 14.2 21.3 43.5 21.8 21.0 20.9 34.7 22.9 29.6 6.0 32.0 11.3 26.7 37.0 12.7 40.6 49.2 40.5 60.3 40.7 47.7 43.9 43.1 44.9 45.0 43.3 72.6 23.3 22.4 25.8 129.3 29.8 56.0 131.4 74.9 34.1 35.3 39.1 24.1 28.6 42.9 51.3 36.8 102.2 53.6 18.8 53.5 115.4 27.4 230.2 48.0 21.4 33.3 37.8 13.0 46.4 29.4 22.3 27.7 29.6 39.3 10.2 41.1 89.3 117.4 35.3 25.2 51.5 31.4 71.2 15.7 11.7 62.9 34.8 15.9 46.2 52.5 14.1 35.5 39.1 104.0 141.1 15.6 26.6 45.5 23.3 27.9 32.4 376.2 47.6 50.5 39.5 29.9 26.2 18.0 29.4 45.5 40.6 20.0 30.7 61.7 62.7 67.8 HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 subunit alpha" Q16665 14 61695513-61748259 "Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 448.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 155.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 155.0" "Cell line enhanced" "Detected in many" "LHCN-M2: 941.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (9.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.77e-2)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (3.58e-1)" "unprognostic (7.35e-2)" "unprognostic (3.88e-2)" 64.9 133.7 22.1 146.6 24.0 448.3 36.2 28.2 26.1 132.9 24.7 42.8 33.6 52.4 74.8 62.1 41.1 145.4 36.5 21.1 28.4 104.2 51.6 75.7 71.4 29.7 29.7 35.3 36.0 91.7 30.7 77.6 33.3 46.9 41.7 35.5 45.3 67.2 12.1 34.2 37.3 59.1 27.2 72.4 37.6 32.4 38.5 55.8 49.5 17.6 88.2 169.9 43.1 26.5 313.6 123.6 112.7 344.7 185.2 297.1 161.5 253.8 270.1 288.7 258.9 54.1 100.3 75.8 186.2 293.0 73.6 71.8 71.0 416.1 352.5 33.7 41.0 46.5 105.3 93.1 414.8 20.1 49.3 523.4 129.2 216.5 225.6 408.6 198.1 44.4 32.3 0.4 941.4 65.6 59.2 24.3 108.9 49.6 159.7 4.3 269.1 22.8 400.2 204.3 100.3 111.9 472.5 67.0 170.7 148.9 70.6 36.3 119.2 700.2 157.3 235.9 215.2 39.1 61.2 84.1 369.9 38.5 194.7 43.8 22.3 155.0 11.5 18.0 14.4 19.5 15.0 13.3 19.6 19.0 22.6 15.6 56.3 19.7 19.4 9.2 11.0 18.4 22.1 24.0 28.2 26.1 21.1 28.4 29.7 29.7 33.3 27.2 38.5 26.5 93.3 70.5 116.0 69.2 157.3 106.4 101.8 102.6 97.9 54.1 38.5 30.1 43.5 87.2 69.0 261.1 50.1 24.8 65.1 44.1 103.7 278.5 3.6 95.6 131.3 152.3 66.4 35.3 45.6 251.6 67.1 81.4 49.5 272.3 223.6 339.7 176.0 30.7 136.4 156.5 39.3 39.0 57.0 145.9 111.7 6.2 24.2 240.2 103.2 53.4 87.1 134.0 26.8 78.9 35.8 236.9 21.9 48.5 60.0 59.3 20.2 192.1 37.7 54.8 52.6 75.8 136.9 80.5 44.2 128.7 87.9 25.4 91.6 92.2 51.8 116.0 HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 49.9;Excitatory neurons: 80.7;Inhibitory neurons: 76.2;Oligodendrocytes: 23.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" 1.4 3.6 6.1 0.2 5.9 0.0 1.4 5.9 5.2 0.8 0.0 0.8 0.2 0.2 0.0 1.0 0.4 0.6 1.8 5.5 10.6 0.9 0.7 2.6 0.3 5.6 6.3 0.4 1.6 0.1 4.7 6.2 6.6 3.0 0.8 4.5 0.8 1.0 1.1 0.1 0.9 0.5 9.2 0.0 1.0 2.6 8.3 0.6 0.4 2.8 0.2 0.9 0.7 9.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.9 5.9 5.2 5.5 10.6 5.6 6.3 6.6 9.2 8.3 9.4 0.6 0.0 1.3 49.9 0.0 0.0 0.0 0.0 1.2 15.1 3.7 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.5 0.0 0.0 80.7 0.0 0.0 5.8 0.0 0.0 0.0 3.5 3.9 0.0 0.1 0.0 76.2 0.0 0.0 0.3 0.0 1.3 0.3 0.1 0.0 15.0 0.0 1.5 0.0 5.5 23.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.9 5.6 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HS3ST5 3-OST-5 ENSG00000249853 "Heparan sulfate-glucosamine 3-sulfotransferase 5" Q8IZT8 6 114055586-114343045 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;skeletal muscle: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 102.5;Excitatory neurons: 154.8;Inhibitory neurons: 130.9;Oligodendrocytes: 606.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 4.6;RT4: 6.8;SCLC-21H: 14.2;U-266/70: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021823, HPA064677" Approved NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA021823: AB_1851100, HPA064677: AB_2685318" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-2)" "unprognostic (1.04e-2)" "unprognostic (1.72e-2)" "unprognostic (3.00e-2)" "unprognostic (7.98e-4)" "unprognostic (5.39e-2)" "unprognostic (6.29e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.53e-2)" 0.0 0.3 3.5 0.1 9.7 0.2 0.0 3.6 4.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 4.5 0.1 0.0 0.1 0.0 7.2 7.0 0.0 0.2 0.0 0.0 0.0 7.3 0.0 0.1 1.1 0.0 1.3 3.2 0.2 0.1 0.1 6.5 0.0 0.2 0.1 7.6 0.0 0.0 1.4 0.0 2.2 0.0 6.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 1.9 4.6 0.0 0.8 0.0 0.0 6.8 14.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.1 4.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 9.7 3.6 4.4 2.8 4.5 7.2 7.0 7.3 6.5 7.6 6.0 0.0 0.0 0.0 102.5 0.0 1.3 0.0 0.0 0.0 3.8 0.0 0.0 0.6 0.0 0.0 11.0 18.8 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.1 0.0 0.0 154.8 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 130.9 0.4 0.0 0.0 0.0 0.8 3.7 0.0 0.0 9.4 0.0 0.0 0.0 11.6 606.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 7.9 0.1 1.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.5 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873020-32044633 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 9.8" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 109.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;BEWO: 16.3;RH-30: 18.1;SCLC-21H: 14.8;SiHa: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA027295: AB_2672203, HPA027372: AB_2672239" "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 0.7 1.0 0.8 1.3 1.3 0.2 1.2 0.4 4.7 0.4 0.0 3.6 1.4 4.1 1.9 0.4 1.9 0.5 0.4 4.2 2.6 3.7 0.5 0.9 0.4 0.4 0.1 0.6 9.8 0.1 1.1 4.6 0.1 0.9 3.7 3.0 0.6 2.1 0.3 3.0 2.7 2.4 0.0 0.1 1.3 0.9 0.2 0.7 0.6 0.2 0.6 1.5 0.7 1.6 0.0 3.9 13.2 0.1 0.0 0.0 16.3 1.3 0.0 0.2 0.0 5.3 0.1 0.0 0.5 6.2 0.2 0.0 7.7 0.0 0.1 0.1 3.9 0.0 3.7 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 1.1 0.2 1.1 10.2 0.1 0.1 0.1 18.1 0.1 1.3 0.0 14.8 9.8 13.2 1.0 0.5 9.3 5.5 1.4 0.0 0.1 9.3 0.1 0.0 0.1 0.0 1.8 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.4 4.7 4.2 2.6 0.4 0.1 0.1 0.0 0.2 1.6 0.2 6.4 9.1 7.5 0.0 5.1 2.6 0.2 0.6 8.1 0.5 2.8 3.5 14.3 3.0 7.3 2.1 9.2 0.0 4.6 0.0 5.3 0.2 1.2 1.3 0.8 4.9 0.0 19.0 3.3 13.9 7.9 0.5 3.4 0.0 4.3 0.4 1.0 2.7 3.3 109.6 5.1 0.0 0.0 4.2 0.1 0.3 0.4 3.6 1.0 0.1 8.1 0.0 10.1 1.5 1.6 4.4 0.0 0.0 2.1 1.8 1.9 0.8 1.2 0.0 6.3 2.2 0.7 1.1 0.7 5.8 6.2 0.5 0.0 10.6 0.9 ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 594.7;Late spermatids: 867.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 29.9" "Lineage enriched" "Detected in many" 9 "T-cells: 29.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.1;MCF7: 42.5;OE19: 48.4;RT4: 49.4;SCLC-21H: 66.1;SH-SY5Y: 105.8;SK-BR-3: 52.1;T-47d: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: AB_2684525" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" 15.8 10.4 11.3 5.7 16.2 23.8 21.1 21.5 21.8 16.4 1.2 22.8 13.6 6.8 13.6 9.5 13.7 11.1 44.3 13.4 9.3 16.0 8.8 11.2 13.5 8.0 9.5 1.7 62.7 20.9 19.8 8.2 9.3 22.1 23.5 2.9 37.1 4.9 2.8 12.8 17.8 5.6 5.1 12.4 30.5 24.2 13.3 5.0 14.1 3.3 9.6 13.8 7.4 15.3 0.0 1.5 1.7 0.2 0.2 0.0 4.2 0.0 0.0 0.6 0.2 1.0 47.1 0.3 5.2 0.1 0.9 0.0 0.8 1.9 0.0 0.0 6.8 9.1 0.9 0.0 0.4 9.1 1.8 0.0 3.0 0.0 0.0 0.5 31.5 8.2 26.4 0.0 0.0 42.5 0.4 0.0 9.9 48.4 0.4 0.0 0.0 19.5 19.0 49.4 66.1 105.8 0.0 52.1 0.7 11.6 43.4 14.3 19.8 0.0 0.9 0.2 1.0 14.1 7.5 0.0 0.0 6.9 10.3 1.0 2.4 0.2 0.3 0.8 0.6 0.4 5.4 0.4 2.4 0.7 0.3 0.2 3.4 0.9 0.4 0.6 29.9 1.3 11.3 16.2 21.5 21.8 13.4 9.3 8.0 9.5 9.3 5.1 13.3 15.3 73.4 28.9 24.4 6.5 1.6 20.5 16.2 7.1 9.1 10.4 42.8 28.7 43.2 22.8 20.1 22.0 6.2 2.7 2.1 28.2 43.0 38.4 594.7 34.2 5.8 44.1 77.2 16.4 132.1 74.8 0.8 4.5 56.1 65.4 8.2 11.2 42.1 1.3 23.9 0.0 138.0 80.5 44.7 8.1 9.3 867.0 7.5 9.6 14.2 60.0 6.3 0.8 3.1 49.3 3.9 59.8 53.1 3.0 1.7 53.8 23.8 8.3 17.8 1.7 6.6 1.2 5.6 13.9 9.6 18.4 8.9 2.2 9.5 4.7 41.8 42.7 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Proximal enterocytes: 84.2;Proximal tubular cells: 224.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: AB_2683716" "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" 8.9 12.0 18.8 6.1 24.5 5.8 8.7 20.6 26.8 4.3 22.7 9.5 26.3 5.3 13.3 8.3 12.9 6.4 5.8 19.1 22.6 50.9 70.5 7.3 11.0 20.3 20.8 5.5 13.8 14.8 9.0 3.0 20.6 8.4 9.2 10.9 8.8 9.5 2.3 7.1 26.9 4.4 20.5 7.9 8.9 3.7 20.8 38.9 13.2 2.6 9.5 5.2 3.9 21.1 4.3 10.4 1.7 1.8 4.6 6.9 7.8 3.4 8.6 3.5 2.8 2.9 5.3 5.8 5.2 5.8 3.5 8.4 1.3 2.0 3.6 11.9 1.6 2.1 4.6 12.7 19.4 1.5 2.8 4.3 3.3 7.2 7.2 6.2 7.9 16.0 1.9 7.1 4.8 26.8 3.7 1.4 1.6 18.1 6.0 4.6 4.2 3.3 9.6 5.5 6.9 8.6 7.5 6.5 7.6 2.5 6.0 8.1 7.4 1.6 1.3 14.3 6.1 9.0 10.4 1.0 7.3 2.4 2.8 100.7 13.0 19.1 30.5 24.1 25.4 39.3 26.0 24.7 18.1 26.7 20.2 27.2 2.8 33.1 47.6 20.9 52.2 24.8 18.8 24.5 20.6 26.8 19.1 22.6 20.3 20.8 20.6 20.5 20.8 21.1 6.2 12.8 8.7 14.7 9.3 6.8 3.2 7.3 4.0 8.9 10.0 8.4 9.9 10.0 8.8 5.5 0.0 8.0 11.3 8.4 80.3 11.3 0.4 34.6 2.0 5.6 7.3 2.5 4.7 16.1 4.6 8.0 4.6 7.0 20.8 10.2 3.3 44.3 11.1 10.1 5.6 12.8 12.2 11.6 7.5 2.0 4.4 8.2 12.4 11.2 19.8 38.0 24.7 8.0 11.4 5.4 21.7 4.1 12.1 4.6 84.2 224.4 28.3 3.5 0.0 8.8 5.9 1.4 1.5 5.4 5.8 3.0 13.7 9.9 11.2 4.2 IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" 95.7 37.9 13.5 114.5 17.5 35.5 72.8 14.3 14.1 56.8 9.1 38.3 23.8 76.5 22.7 63.6 54.2 100.6 35.0 13.7 20.3 30.1 27.7 68.2 140.6 29.9 22.7 76.8 16.7 9.7 9.3 66.7 27.0 26.5 45.0 7.7 63.7 32.0 16.8 58.8 47.9 87.3 23.6 107.8 30.7 18.8 23.8 116.8 37.4 32.6 133.1 113.6 52.8 26.2 43.5 3.2 14.4 0.6 97.4 319.5 0.4 89.9 238.0 245.7 324.2 0.0 54.1 251.7 75.4 55.3 79.2 122.2 2.2 91.1 97.7 78.4 1.1 64.9 17.2 0.1 181.8 22.8 4.2 302.4 159.5 126.5 177.8 117.8 262.8 218.1 1.4 179.4 138.6 0.0 302.2 21.1 38.4 0.0 32.5 140.6 91.4 295.0 34.4 16.1 6.6 0.1 117.7 1.0 259.5 56.9 0.4 26.3 150.2 63.1 29.7 179.9 38.2 165.8 82.8 235.5 181.2 72.7 155.7 9.1 67.7 0.4 57.5 66.4 51.9 88.4 54.3 59.4 68.3 94.6 33.9 43.3 164.4 91.6 65.3 51.1 82.1 63.8 13.5 17.5 14.3 14.1 13.7 20.3 29.9 22.7 27.0 23.6 23.8 26.2 378.4 38.5 54.6 4.2 217.8 95.0 110.7 197.6 174.8 0.4 47.8 43.8 10.7 37.1 130.7 42.3 0.0 3.4 278.3 7.9 1.9 38.0 4.9 41.9 219.1 286.8 12.1 38.7 1.3 47.8 2.9 207.8 9.7 68.0 138.3 27.7 137.4 3.0 214.2 0.0 2.2 19.9 79.3 163.8 135.0 9.8 117.4 187.2 83.6 116.2 202.4 30.8 329.6 37.2 20.7 47.1 23.5 53.0 143.3 32.6 7.9 4.9 76.6 1.4 85.5 185.3 132.7 2.4 13.2 92.6 68.2 3.3 219.2 70.6 26.4 107.5 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IFI6 "6-16, FAM14C, G1P3, IFI-6-16, IFI616" ENSG00000126709 "Interferon alpha inducible protein 6" P09912 1 27666064-27672212 "Predicted membrane proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 4084.0;Extravillous trophoblasts: 1291.2;Syncytiotrophoblasts: 4273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 1349.9;BJ hTERT+ SV40 Large T+ RasG12V: 1570.7;EFO-21: 544.1;SK-MEL-30: 1075.0" "Low region specificity" "Detected in all" HPA005543 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA005543: AB_1849342" "unprognostic (4.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (6.96e-2)" "unprognostic (9.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (6.77e-3)" "unprognostic (5.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.92e-3)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" 84.0 161.4 117.5 37.5 142.0 113.2 73.1 106.8 159.3 99.7 164.7 76.3 44.0 55.6 39.1 30.5 49.6 56.8 114.2 126.4 168.7 154.1 135.6 143.5 14.9 200.8 145.5 81.4 57.2 116.0 316.7 298.2 155.6 60.6 24.5 17.2 334.3 23.0 23.8 35.3 52.1 43.6 299.5 91.0 96.1 61.9 153.1 62.2 166.9 20.1 14.5 43.8 47.4 139.2 15.6 4.4 22.7 14.1 72.4 38.8 90.6 48.5 220.1 1349.9 1570.7 8.0 58.5 6.1 544.1 22.1 352.4 5.2 5.5 10.8 43.7 117.3 18.4 36.4 11.2 4.8 19.4 12.4 45.1 43.3 1.8 82.1 1.1 20.9 12.6 31.6 2.5 95.2 15.3 4.4 44.1 153.4 4.4 28.7 46.4 29.6 12.1 14.9 12.2 0.9 32.2 28.8 59.9 13.6 1075.0 6.7 6.9 46.5 21.7 12.6 19.3 9.4 8.4 113.5 68.1 4.4 24.6 105.3 35.8 193.3 265.8 252.0 128.7 374.6 127.9 57.3 128.2 118.0 117.6 47.0 132.7 130.9 506.8 102.0 259.4 12.8 172.9 113.2 117.5 142.0 106.8 159.3 126.4 168.7 200.8 145.5 155.6 299.5 153.1 139.2 158.0 141.1 74.4 5.2 26.1 23.5 19.8 39.3 29.0 15.2 17.5 14.4 12.9 54.3 42.2 64.4 10.4 4084.0 44.7 13.2 19.6 244.0 3.4 61.4 76.4 194.8 58.4 27.6 3.6 340.0 1291.2 149.3 21.4 91.8 63.3 186.3 82.8 40.4 685.3 3.3 7.4 60.5 67.1 71.8 49.1 11.5 110.6 169.4 71.2 24.4 93.8 95.1 46.4 16.1 3.9 214.2 11.7 204.7 96.0 48.2 16.9 32.7 89.3 5.6 111.7 60.9 63.1 7.9 1.6 5.8 22.4 4273.1 59.6 138.6 13.0 49.0 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IFT80 "FAP167, KIAA1374, WDR56" ENSG00000068885 "Intraflagellar transport 80" Q9P2H3 3 160256986-160399880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 254.5;Respiratory ciliated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035868 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA035868: AB_10959463" "unprognostic (2.71e-2)" "unprognostic (4.47e-3)" "unprognostic (2.13e-1)" "unprognostic (5.29e-2)" "unprognostic (3.03e-1)" "unprognostic (7.25e-2)" "unprognostic (4.08e-3)" "unprognostic (1.29e-2)" "unprognostic (5.95e-2)" "unprognostic (6.70e-2)" "unprognostic (8.31e-2)" "unprognostic (4.24e-3)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (5.60e-3)" 7.5 10.0 17.2 8.3 25.6 6.2 11.5 17.0 26.2 13.3 20.6 7.7 6.1 14.6 16.9 8.9 17.3 11.6 10.0 17.6 20.0 17.9 7.6 14.5 12.1 18.7 21.0 16.5 10.2 27.5 25.7 7.6 18.7 9.8 9.9 25.1 7.3 10.8 4.7 12.3 8.3 10.8 15.4 9.4 11.2 24.1 19.7 18.2 18.2 6.8 11.6 8.9 8.9 40.1 23.9 16.3 36.9 16.9 34.0 59.8 9.1 20.0 29.3 15.1 19.8 13.3 33.9 15.5 25.7 18.9 22.9 20.3 13.1 19.3 33.7 23.1 14.5 20.7 23.4 9.5 33.8 9.9 17.4 33.2 13.0 17.2 18.4 68.1 17.1 19.7 8.9 28.8 23.8 11.5 18.4 11.7 11.6 15.0 9.5 16.3 19.3 26.3 31.5 6.9 22.0 23.2 21.9 20.6 26.1 23.9 34.5 11.3 15.3 15.5 10.5 21.2 19.9 41.7 28.9 28.5 26.7 17.8 15.6 0.9 0.5 0.5 0.6 0.2 0.6 0.8 0.7 0.7 0.7 0.7 1.0 0.7 0.4 0.9 0.5 1.4 1.0 0.6 17.2 25.6 17.0 26.2 17.6 20.0 18.7 21.0 18.7 15.4 19.7 40.1 6.5 41.7 33.0 42.7 7.0 3.3 5.9 7.5 15.4 16.7 6.4 3.8 7.2 18.6 14.4 23.9 16.7 3.1 7.3 3.8 7.9 5.6 30.5 39.0 19.0 7.0 11.4 11.6 61.7 1.8 2.9 13.8 5.6 9.6 2.5 13.3 6.8 4.0 2.9 1.7 44.9 5.2 2.0 4.1 2.7 9.5 16.4 4.4 1.8 27.2 2.5 8.0 7.2 46.3 254.5 2.6 2.6 21.8 10.9 2.4 1.9 6.7 71.7 18.1 6.6 8.3 8.3 43.2 10.4 8.5 3.8 0.7 8.8 11.6 5.1 3.6 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 672.7;Endometrial stromal cells: 542.2;Endothelial cells: 502.3;Fibroblasts: 585.4;Hepatic stellate cells: 566.5;Hepatocytes: 501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.5;NK-cell: 37.0" "Group enriched" "Detected in many" 5 "NK-cells: 37.0;T-cells: 19.5" "Cell line enhanced" "Detected in many" "A549: 1334.8;ASC diff: 961.5;ASC TERT1: 933.8;BJ: 1066.4;BJ hTERT+: 1088.2;HSkMC: 2001.2;U-2197: 882.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" NA NA 227000000 410000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" 884.7 248.1 26.0 307.7 26.9 2.4 754.6 25.3 46.5 1020.7 65.0 618.0 82.8 795.8 141.9 246.7 791.1 391.4 502.9 25.6 28.2 464.4 1475.9 390.1 60.0 29.5 34.1 1270.4 164.4 44.6 203.7 231.8 28.9 470.0 133.5 13.1 264.4 279.0 107.3 241.7 289.5 645.1 28.3 295.5 369.6 67.7 35.3 38.9 501.4 97.4 44.2 552.1 576.2 25.8 0.2 1334.8 66.8 0.5 961.5 933.8 2.2 1066.4 1088.2 199.7 154.4 59.7 17.3 0.3 563.7 511.0 27.2 11.9 22.6 6.8 90.2 4.8 1.3 4.3 91.3 89.9 601.2 2.9 0.5 2001.2 4.6 267.7 37.7 23.8 350.6 0.1 21.7 0.2 290.5 41.2 0.8 252.5 37.2 58.9 178.2 67.2 1.3 2.1 8.4 42.1 18.3 53.0 482.3 2.0 17.0 63.5 486.6 24.7 534.7 276.0 14.4 882.1 1.1 0.9 0.6 1.7 163.8 9.9 72.4 0.0 0.0 0.0 2.7 0.0 19.5 0.8 5.0 6.7 0.0 5.2 0.3 0.6 0.0 37.0 0.0 0.2 0.0 1.4 26.0 26.9 25.3 46.5 25.6 28.2 29.5 34.1 28.9 28.3 35.3 25.8 672.7 9.6 37.4 1.3 17.6 56.3 97.1 36.7 79.1 3.2 118.9 163.2 16.9 90.1 16.2 7.3 0.0 6.1 10.6 93.3 17.6 4.1 6.7 69.8 542.2 502.3 8.4 37.9 3.8 2.4 7.2 585.4 13.7 59.1 2.5 230.9 566.5 501.2 273.6 1.7 3.4 74.7 4.1 42.8 94.0 16.5 246.4 21.3 72.9 18.7 3.4 3.8 1.0 1.0 0.3 39.1 72.1 118.5 7.4 63.8 71.6 204.7 18.5 1.1 190.7 13.8 299.9 1.9 8.2 26.8 47.7 7.5 20.3 25.9 109.0 73.6 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 256.5;WM-115: 239.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA036305: AB_2675050, HPA036306: AB_10671245" "unprognostic (9.87e-2)" "unprognostic (3.64e-1)" "unprognostic (9.51e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (4.03e-6)" "unprognostic (9.40e-2)" "unprognostic (4.41e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.87e-6)" "unprognostic (5.29e-2)" "unprognostic (4.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" 1.5 1.8 0.9 1.3 1.8 0.3 8.5 1.8 3.9 6.1 1.4 6.5 7.7 2.9 5.7 23.2 2.0 3.2 9.1 1.1 3.0 11.4 0.5 8.4 0.5 2.0 3.5 0.4 2.6 2.1 2.4 11.1 2.3 5.6 5.8 7.5 9.1 5.7 1.6 18.2 8.8 2.9 4.7 0.4 8.7 4.1 4.9 10.9 8.3 1.5 5.3 5.0 10.9 2.9 22.3 36.9 28.2 7.2 6.4 13.4 75.5 0.1 1.0 2.9 1.0 21.5 12.4 0.0 11.4 0.3 15.8 60.7 12.6 30.4 1.3 256.5 9.3 12.1 13.7 0.6 0.0 1.2 22.2 1.7 23.1 0.2 5.2 5.3 0.2 4.1 3.7 0.2 0.6 78.0 0.9 0.8 17.8 13.4 0.9 9.1 34.6 0.1 21.6 27.5 16.4 50.0 8.9 84.7 55.1 53.9 28.7 1.5 0.1 4.9 16.4 0.2 23.0 0.3 1.3 0.1 2.2 0.7 239.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 1.8 3.9 1.1 3.0 2.0 3.5 2.3 4.7 4.9 2.9 3.5 16.0 36.0 1.0 0.0 19.6 8.6 23.2 23.9 29.3 17.1 10.8 16.1 7.2 9.1 14.7 0.0 13.7 0.1 29.3 3.9 14.0 2.1 8.3 2.1 3.3 3.0 0.0 11.8 1.9 27.3 7.8 16.8 14.4 1.3 7.3 1.8 0.6 2.1 6.7 18.8 5.0 2.0 1.3 11.1 2.2 1.2 0.5 8.8 0.0 3.1 11.3 0.0 1.5 0.4 16.4 7.3 0.0 0.0 10.2 15.4 11.4 11.3 0.8 0.0 26.4 2.8 0.5 3.8 30.6 27.7 13.3 0.4 3.5 9.3 11.4 IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Cell line enhanced" "Detected in all" "BJ: 206.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" 14.0 7.1 2.3 15.3 2.8 5.1 10.1 2.3 3.1 12.6 5.0 6.6 4.1 10.3 5.8 4.8 6.7 12.9 9.3 2.3 2.9 8.3 10.3 11.0 12.6 3.2 2.7 5.9 5.8 4.2 7.7 26.8 3.2 6.8 7.0 1.2 6.1 7.4 2.6 3.1 5.7 16.0 2.9 11.8 5.6 4.6 3.1 11.6 9.3 4.8 9.6 17.1 7.4 3.7 13.0 39.8 43.5 28.4 102.8 105.8 39.4 206.0 124.7 53.3 67.2 8.8 12.4 42.4 35.5 128.7 37.1 26.7 17.5 80.5 90.1 12.4 26.7 16.2 23.9 59.8 39.3 30.2 31.1 81.1 16.6 62.4 54.5 95.3 75.3 7.8 25.5 16.0 133.3 11.8 14.0 68.7 16.9 10.2 33.5 11.9 64.0 21.7 88.9 14.6 6.6 20.8 58.9 4.1 34.1 73.6 13.1 37.0 71.6 115.7 41.3 50.5 53.9 17.2 20.1 31.8 33.3 27.2 85.1 11.4 6.4 19.3 2.8 4.9 3.3 5.9 1.8 2.9 5.4 3.8 2.0 2.0 28.1 5.0 5.7 3.7 2.6 1.8 2.3 2.8 2.3 3.1 2.3 2.9 3.2 2.7 3.2 2.9 3.1 3.7 44.9 12.8 15.7 1.6 34.4 7.6 15.5 55.6 21.6 2.8 7.9 22.4 3.0 0.0 18.7 3.7 4.2 35.5 32.5 2.3 11.7 10.5 2.8 7.9 47.4 47.7 0.0 19.8 5.9 5.8 65.3 47.0 2.6 4.4 20.8 32.7 44.3 8.4 45.7 3.3 3.3 4.8 12.2 31.2 34.1 3.6 30.7 35.4 14.2 14.0 40.4 2.0 37.0 11.6 2.2 5.1 3.1 17.0 74.8 7.6 1.0 10.1 6.3 2.6 39.5 27.8 46.8 32.1 16.0 9.0 7.2 10.1 23.6 25.3 2.9 6.5 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.2;myeloid DC: 17.2;neutrophil: 29.2" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.2;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 181.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001587 Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles Nucleoplasm "HPA001587: AB_1079133" "unprognostic (5.14e-3)" "unprognostic (4.72e-2)" "unprognostic (7.12e-2)" "unprognostic (7.75e-2)" "unprognostic (8.81e-3)" "unprognostic (3.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.44e-1)" "unprognostic (1.90e-1)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.82e-2)" "unprognostic (5.08e-2)" 51.9 34.3 15.9 40.3 16.2 7.1 41.5 18.1 17.3 27.1 20.4 52.1 48.5 31.9 26.2 53.5 35.8 39.3 20.2 14.6 22.3 33.7 120.3 48.9 25.4 26.0 20.3 37.5 22.3 22.2 15.4 32.8 24.6 22.5 61.6 25.6 34.7 27.1 31.4 20.6 60.8 40.6 22.2 29.9 35.8 16.6 19.6 16.0 29.8 55.9 34.5 31.6 27.4 24.6 31.6 37.2 17.4 48.0 39.0 113.5 33.1 63.3 86.2 29.2 37.6 21.8 55.0 0.1 111.4 86.6 84.8 29.1 19.0 26.6 32.3 181.0 16.5 5.1 30.9 55.8 23.4 0.6 13.0 104.1 23.5 40.0 48.8 87.9 61.8 0.0 16.6 3.3 41.9 44.8 0.1 8.5 16.1 57.8 38.6 0.1 43.3 0.2 43.6 32.9 6.5 6.0 102.3 35.5 24.7 22.8 22.8 28.9 79.3 56.7 26.7 99.7 50.5 0.7 16.8 0.3 125.6 16.1 24.6 0.2 10.9 12.2 0.0 2.7 0.1 2.9 0.0 0.0 17.2 2.5 0.0 0.0 29.2 0.1 1.1 2.9 0.1 2.9 15.9 16.2 18.1 17.3 14.6 22.3 26.0 20.3 24.6 22.2 19.6 24.6 36.0 70.5 48.5 1.0 20.2 17.2 37.1 17.2 18.2 2.1 32.4 26.3 11.5 37.1 46.0 29.5 16.7 8.1 2.8 61.9 9.8 36.1 38.1 25.8 34.0 58.8 93.2 4.8 0.3 98.3 31.9 38.7 38.7 27.3 0.0 13.6 78.9 149.0 41.2 0.0 2.0 138.4 16.2 124.8 140.6 7.3 24.2 120.4 21.4 73.1 199.7 43.7 2.1 0.0 6.9 87.9 27.0 18.8 1.3 42.3 70.8 25.2 49.7 11.2 32.9 14.4 26.2 7.5 28.9 37.2 12.1 9.4 2.7 7.1 29.5 30.8 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72005715 "Disease related genes, Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 3070000 16000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 14.4 18.4 6.0 25.0 6.3 7.9 13.6 7.1 9.1 12.5 4.9 12.7 8.3 10.4 3.5 6.4 10.1 8.1 10.9 5.8 8.3 24.9 15.0 31.1 26.2 8.7 7.8 11.1 8.4 2.5 10.7 17.1 9.0 16.5 11.0 3.8 8.9 4.2 5.0 7.4 17.2 13.5 6.1 49.2 10.2 6.1 8.5 6.5 12.6 2.4 11.9 12.2 8.5 7.3 1.7 2.3 5.1 2.9 1.0 1.6 5.9 3.3 1.8 3.0 4.0 11.7 2.4 1.2 2.2 1.3 3.4 4.0 2.5 2.4 2.0 2.5 3.8 4.5 7.6 3.7 1.3 2.4 12.3 2.4 2.3 2.4 1.2 3.5 6.3 7.9 7.4 2.0 1.8 3.2 3.8 5.7 3.6 1.9 2.2 6.1 5.4 1.9 2.1 4.4 2.8 5.3 3.0 4.2 3.7 4.8 3.6 2.7 13.6 4.2 3.5 5.1 1.9 3.3 1.8 2.1 1.7 11.5 2.3 7.0 20.2 56.1 52.5 72.9 23.9 31.9 27.5 31.6 36.9 20.2 22.5 32.5 8.6 5.2 60.9 53.7 15.1 39.8 6.0 6.3 7.1 9.1 5.8 8.3 8.7 7.8 9.0 6.1 8.5 7.3 14.0 6.4 3.3 0.7 8.0 2.0 0.4 0.7 0.0 3.3 2.1 1.9 1.8 1.5 1.0 0.0 10.4 1.0 7.2 0.5 0.0 3.0 0.0 1.1 1.9 11.1 0.0 0.8 0.7 13.6 1.4 3.4 1.1 1.8 7.6 2.2 10.4 0.5 11.2 3.3 0.5 0.8 0.0 14.2 12.9 0.0 0.9 15.4 0.0 1.0 4.6 1.1 7.2 0.5 0.0 5.4 0.2 0.7 2.3 1.0 1.1 1.9 1.8 3.7 0.0 1.8 1.6 0.7 0.5 0.6 2.0 0.8 6.4 1.6 0.8 0.2 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 94.4;Langerhans cells: 68.0;Leydig cells: 137.6;Smooth muscle cells: 218.3;Syncytiotrophoblasts: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 75.9;hTEC/SVTERT24-B: 227.0;hTERT-HME1: 92.9;hTERT-RPE1: 139.2;TIME: 120.1;U-138 MG: 174.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" 2.3 1.5 2.1 5.1 2.0 10.4 0.9 2.3 7.8 1.5 0.7 1.0 0.8 17.3 3.7 2.1 1.2 21.6 5.4 8.7 3.3 2.8 9.5 11.0 1.2 4.3 8.1 6.8 0.6 0.5 0.5 10.9 3.4 3.2 0.6 2.3 5.4 5.0 0.5 2.0 0.5 4.3 4.5 0.5 0.8 1.7 3.0 0.2 1.2 4.6 0.4 10.3 1.1 3.4 4.2 0.0 0.4 0.1 3.3 7.1 0.0 18.2 1.9 9.9 3.3 0.0 0.4 0.0 1.1 6.9 11.6 15.3 0.0 75.9 9.6 5.1 0.0 0.0 0.0 0.0 13.9 0.0 0.2 7.0 4.2 227.0 92.9 139.2 8.2 0.0 0.5 0.0 23.0 0.2 0.0 0.3 1.5 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.1 5.7 11.1 0.6 0.0 6.2 0.1 0.2 120.1 174.7 49.7 18.9 19.0 0.0 0.0 0.0 6.7 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 2.1 2.0 2.3 7.8 8.7 3.3 4.3 8.1 3.4 4.5 3.0 3.4 0.7 3.2 15.7 0.0 0.9 17.3 10.8 13.5 2.2 0.1 3.5 6.5 6.0 0.0 4.4 0.0 0.0 1.4 0.3 0.1 0.0 23.6 0.6 1.4 4.1 5.9 0.0 0.0 2.4 2.0 4.6 42.0 0.0 2.6 7.6 94.4 0.7 18.5 1.5 0.0 0.2 0.2 4.1 1.4 68.0 5.9 137.6 55.8 14.2 0.0 27.0 16.1 0.0 4.0 0.3 11.1 0.1 23.3 0.0 12.5 0.0 0.1 2.8 1.3 0.0 4.9 218.3 0.7 0.3 1.4 8.9 178.4 1.7 18.8 0.2 2.3 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 123.2;thyroid gland: 204.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 35.0;Distal enterocytes: 24.0;Inhibitory neurons: 19.5;Muller glia cells: 25.2;Proximal enterocytes: 62.3" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 19.6;SK-BR-3: 41.1;T-47d: 25.7;U-698: 18.1" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 2.1 3.2 0.8 4.8 0.1 8.9 17.3 13.2 4.0 2.4 10.4 16.3 3.0 0.6 2.4 2.3 1.2 27.8 11.5 15.2 32.1 0.4 2.3 0.5 6.0 4.0 1.2 15.7 123.2 10.1 0.1 5.2 9.2 3.7 5.3 33.1 12.1 2.8 4.4 26.2 1.5 1.4 0.3 13.6 4.4 8.3 0.2 204.2 2.6 0.4 2.7 2.4 5.7 2.1 2.0 1.2 2.3 0.3 0.2 1.1 0.8 0.8 4.1 4.0 1.2 1.3 0.1 1.0 0.4 0.4 2.4 2.5 1.2 1.7 0.0 6.5 0.0 9.7 0.4 0.8 19.6 0.2 0.2 1.3 3.4 0.4 2.7 0.3 0.1 1.8 2.8 0.1 6.4 0.1 0.1 2.3 2.8 0.4 0.0 0.4 4.5 1.7 2.5 9.9 7.5 1.6 41.1 0.5 1.1 25.7 1.6 0.0 0.2 7.3 0.8 0.5 0.1 3.5 18.1 0.7 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 4.8 17.3 13.2 11.5 15.2 6.0 4.0 5.2 1.4 8.3 5.7 0.7 0.0 4.1 3.3 0.0 0.9 2.3 0.3 1.2 9.5 15.8 7.5 6.1 0.0 1.1 35.0 0.0 0.0 0.2 24.0 11.7 1.4 0.4 1.9 0.4 0.5 0.0 0.0 5.5 2.2 0.2 0.6 4.6 2.7 0.0 0.8 0.0 0.0 0.1 5.0 19.5 6.4 0.0 0.0 1.9 0.6 0.0 0.3 0.0 1.0 0.6 25.2 0.0 2.0 1.0 0.8 12.3 0.0 0.1 2.5 62.3 0.5 0.5 3.1 0.0 0.5 1.3 2.4 1.2 1.1 1.3 0.1 0.4 0.4 8.8 1.6 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859117 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.5;kidney: 3.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.9;Cardiomyocytes: 2.3;Early spermatids: 2.8;Spermatocytes: 4.1;Spermatogonia: 5.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "medulla oblongata: 14.5;pons: 13.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 4.6;SH-SY5Y: 15.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA025285 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.5 1.4 0.0 0.0 0.5 0.0 0.2 1.2 1.9 1.3 0.2 0.1 0.0 0.5 0.0 0.0 0.4 0.0 0.2 0.0 0.5 3.8 0.0 0.0 0.0 14.5 0.6 0.0 0.2 0.0 0.6 0.0 13.4 0.6 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.3 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.9 0.0 0.5 14.5 0.6 13.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899162-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.5;lymphoid tissue: 244.1" "Cell type enhanced" "Detected in many" "B-cells: 225.8;dendritic cells: 492.3;Kupffer cells: 105.1;Langerhans cells: 366.0;Macrophages: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2477.4" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2477.4" "Group enriched" "Detected in some" 4 "Daudi: 240.7;THP-1: 382.3;U-698: 928.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013480: AB_2533439, HPA002267: AB_1079143, HPA002531: AB_1851904" "unprognostic (2.09e-3)" "unprognostic (7.51e-2)" "unprognostic (5.16e-2)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (3.46e-3)" "unprognostic (3.19e-2)" "unprognostic (5.31e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (5.31e-2)" "unprognostic (3.14e-3)" "unprognostic (3.97e-2)" "unprognostic (9.66e-3)" "unprognostic (4.04e-1)" "unprognostic (1.10e-2)" 25.9 7.6 4.7 81.4 5.6 85.5 9.3 7.0 6.2 5.6 5.4 27.1 47.1 8.0 3.1 6.7 6.5 19.7 3.8 6.3 5.4 6.1 36.9 27.4 244.1 9.5 8.5 2.5 3.4 1.7 1.7 10.1 10.0 7.7 33.5 0.8 7.1 8.9 2.0 5.0 56.2 13.5 11.3 137.3 22.9 4.8 12.6 61.5 4.1 1.7 224.9 21.8 1.6 14.0 0.9 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 26.0 0.0 240.7 1.5 0.0 0.0 0.1 1.4 0.0 0.2 0.2 2.7 0.1 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.5 0.0 0.0 0.6 21.3 0.2 20.6 0.0 7.5 1.1 27.2 0.0 0.0 0.1 0.1 1.0 0.0 0.2 1.4 0.0 382.3 0.6 0.0 10.9 0.2 0.9 0.3 0.3 928.2 0.0 128.4 0.0 9.1 137.1 3.4 3.3 134.3 4.5 347.0 1.8 2.1 291.2 361.3 3.5 2.8 8.4 111.5 97.3 2477.4 0.7 150.1 4.7 5.6 7.0 6.2 6.3 5.4 9.5 8.5 10.0 11.3 12.6 14.0 3.7 0.0 4.2 0.0 225.8 10.5 0.8 0.0 0.6 0.0 2.4 3.4 1.5 2.8 1.3 0.0 0.0 0.8 492.3 13.0 1.9 0.5 1.5 7.3 7.6 7.6 28.7 7.4 0.6 1.4 5.7 10.8 15.3 12.5 2.5 0.4 1.8 6.5 64.1 0.0 0.2 11.8 0.0 105.1 366.0 4.6 0.3 122.2 44.4 33.7 35.3 0.4 23.7 1.0 0.4 0.1 10.7 0.0 14.1 2.3 34.2 3.5 0.0 0.2 6.6 0.7 6.7 0.7 6.7 0.4 9.2 1.1 23.1 48.8 25.6 2.5 ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.1;granulocytes: 74.0;Hofbauer cells: 45.1;Kupffer cells: 51.5;Langerhans cells: 77.3;Macrophages: 141.7;Microglial cells: 56.2;NK-cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 6 "HMC-1: 106.1" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871" Enhanced NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB004458: AB_626859, CAB072871: AB_2665723, HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" 12.9 2.3 6.0 42.7 8.1 48.1 4.3 8.8 33.7 2.2 8.4 2.9 2.3 2.8 0.8 2.0 5.9 10.8 3.5 6.2 9.3 2.9 6.3 58.1 23.2 14.6 11.8 1.0 2.9 1.4 2.9 4.6 14.3 3.2 4.3 0.6 4.5 1.5 1.3 2.1 5.5 4.7 13.0 67.5 4.8 0.6 18.4 4.0 2.8 3.2 12.3 9.2 2.1 24.8 0.1 0.6 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.0 9.0 0.0 0.3 0.1 0.0 0.3 0.1 18.6 0.1 0.1 0.3 0.4 0.0 1.1 106.1 0.1 0.1 1.7 0.2 0.7 1.0 0.0 0.1 0.4 0.0 0.0 0.1 8.8 0.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.1 0.0 3.3 0.8 0.0 1.6 0.0 0.1 0.1 0.0 0.2 4.9 1.8 0.3 12.8 29.1 27.1 4.8 50.3 0.4 2.1 0.1 0.7 34.7 1.0 0.1 0.7 87.5 41.4 61.0 0.6 0.1 11.5 6.0 8.1 8.8 33.7 6.2 9.3 14.6 11.8 14.3 13.0 18.4 24.8 0.8 12.8 51.1 0.0 9.8 2.8 0.3 0.0 0.0 0.1 0.6 1.3 1.5 0.0 10.5 0.0 0.0 0.4 33.6 0.0 0.0 0.3 0.0 0.4 0.5 4.8 0.0 3.4 0.2 0.0 0.6 4.4 0.0 0.5 74.0 0.0 1.1 0.1 45.1 0.0 0.3 0.0 0.0 51.5 77.3 0.0 0.0 141.7 1.8 56.2 35.3 0.1 68.0 0.5 0.3 0.2 0.0 0.0 5.5 0.2 0.0 0.3 1.5 0.1 0.0 0.6 1.0 0.0 0.2 0.0 1.1 0.4 16.5 0.1 0.0 0.1 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCTD10 "BTBD28, MSTP028" ENSG00000110906 "Potassium channel tetramerization domain containing 10" Q9H3F6 12 109448655-109477359 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014273 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA014273: AB_1852159" "unprognostic (7.21e-3)" "unprognostic (3.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.32e-4)" "unprognostic (1.84e-2)" "unprognostic (1.85e-1)" "unprognostic (7.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.45e-1)" "unprognostic (7.72e-2)" "unprognostic (5.76e-2)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" 40.3 23.4 20.5 26.2 19.7 15.4 32.9 17.2 20.3 34.2 32.1 42.5 14.7 43.8 14.0 36.6 27.4 33.0 24.1 19.7 31.0 23.0 11.4 31.9 21.9 21.1 23.1 18.1 12.4 22.2 17.0 25.4 26.6 29.2 33.2 14.3 20.7 44.3 11.5 30.3 22.3 57.0 19.2 23.2 25.8 16.3 30.1 14.9 47.1 11.7 22.8 39.0 29.4 18.9 28.4 27.9 84.6 27.5 67.8 91.2 18.5 59.0 80.2 38.8 38.2 28.1 23.1 27.5 34.0 136.4 19.2 22.0 30.7 51.6 35.9 26.0 22.0 32.3 19.2 19.3 44.5 24.9 26.7 92.2 30.7 50.0 29.3 54.7 89.5 26.4 21.5 11.5 68.0 15.1 29.8 32.9 48.1 12.7 36.0 29.2 37.7 22.6 38.5 48.9 29.5 44.3 35.6 38.8 41.8 47.5 45.2 18.8 70.0 42.3 15.5 24.0 32.8 26.0 52.8 37.1 48.8 20.2 60.5 10.9 9.5 6.4 13.5 14.4 10.1 6.6 8.0 10.0 11.9 6.2 8.8 11.1 6.5 25.1 17.2 9.0 10.0 14.9 20.5 19.7 17.2 20.3 19.7 31.0 21.1 23.1 26.6 19.2 30.1 18.9 21.1 16.0 29.9 6.2 9.0 14.7 20.1 17.4 11.4 5.4 12.1 13.5 11.5 10.0 13.7 5.5 16.7 9.1 19.4 31.5 5.9 15.3 12.2 9.9 17.8 26.8 11.5 6.5 9.8 13.1 12.8 15.5 10.7 12.8 14.0 11.3 24.7 5.3 11.5 8.4 8.1 13.4 10.2 13.6 13.3 11.3 11.5 14.6 16.0 8.4 15.7 2.8 81.4 8.0 9.4 25.9 11.8 18.8 7.5 12.2 6.4 10.5 12.2 4.4 26.3 13.4 32.6 13.5 6.3 10.2 16.6 13.5 10.6 10.4 15.0 18.1 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 73.2;Fibroblasts: 54.7;Intestinal goblet cells: 70.6;Proximal enterocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 267.0;BJ: 180.5;BJ hTERT+: 182.0;fHDF/TERT166: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043477: AB_10962952, HPA076405: AB_2686797" "unprognostic (1.76e-1)" "unprognostic (3.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-1)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.05e-10)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (8.24e-2)" "unprognostic (2.07e-2)" 13.4 4.4 0.9 7.6 1.3 2.0 12.2 2.9 2.1 31.1 8.7 18.1 15.4 7.5 29.5 4.8 7.4 19.6 15.7 1.3 0.9 8.5 12.6 10.3 3.2 1.5 1.7 3.5 15.9 12.1 14.2 16.0 1.1 19.7 22.5 3.1 34.4 10.9 2.1 4.1 18.5 15.5 1.3 2.5 35.0 3.9 1.1 1.7 6.3 3.7 7.2 12.5 4.4 1.5 35.8 11.1 8.7 37.2 142.7 267.0 6.4 180.5 182.0 42.7 105.3 22.1 45.1 0.3 38.2 289.3 15.2 5.1 8.9 10.7 51.0 0.4 21.8 2.5 8.7 55.2 62.9 0.4 24.1 99.9 8.0 53.9 5.7 60.1 52.4 0.3 9.0 0.1 70.7 56.8 0.1 1.3 2.1 150.2 33.2 0.2 2.4 11.8 51.5 4.8 0.7 4.6 46.7 2.7 22.9 3.6 13.3 2.4 41.5 45.8 29.0 160.3 18.0 1.7 0.6 0.2 73.5 0.1 65.0 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.0 0.0 1.6 0.2 0.1 0.9 1.3 2.9 2.1 1.3 0.9 1.5 1.7 1.1 1.3 1.1 1.5 14.5 0.0 4.8 0.3 4.5 7.6 5.7 7.5 1.2 1.3 10.0 4.2 2.5 8.6 10.0 14.7 2.1 5.1 0.3 9.1 7.9 19.0 0.2 8.0 19.4 10.2 4.9 0.8 0.7 31.6 73.2 54.7 24.5 11.0 1.3 6.9 14.6 5.3 4.7 0.0 0.5 70.6 0.0 0.9 14.5 0.6 32.6 1.1 16.0 1.9 1.0 6.3 0.0 0.0 0.4 31.5 4.9 16.1 12.8 16.3 40.1 0.8 9.2 1.4 0.0 1.7 20.5 0.5 2.4 1.6 7.1 8.2 2.3 4.2 11.1 7.8 KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 4.1;basal ganglia: 5.6;cerebral cortex: 6.2;hippocampal formation: 5.6" HPA039321 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 50: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 KIFC3 ENSG00000140859 "Kinesin family member C3" Q9BVG8 16 57758217-57863053 "Cancer-related genes, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 169.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 141.8;Early spermatids: 203.7;Late spermatids: 430.5;Rod photoreceptor cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "A549: 215.1;HMC-1: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021240 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA021240: AB_1852509" "unprognostic (1.53e-1)" "unprognostic (3.10e-3)" "unprognostic (8.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "unprognostic (2.29e-1)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (7.66e-3)" "unprognostic (1.59e-2)" "unprognostic (2.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" "unprognostic (4.33e-2)" 30.5 29.0 25.4 25.9 16.6 14.5 23.8 28.2 35.9 22.7 13.4 21.0 30.7 22.2 30.1 26.2 14.8 21.1 62.7 21.2 38.5 169.2 85.6 45.4 13.5 25.7 14.2 19.0 76.6 26.1 30.9 25.6 29.9 26.3 13.4 82.3 22.1 22.3 13.7 80.0 37.4 13.0 7.3 21.2 24.5 64.9 35.0 4.1 68.1 6.6 9.6 30.3 24.4 46.4 41.5 215.1 15.2 32.8 4.9 10.4 26.8 51.1 65.1 76.4 36.3 58.2 62.6 4.4 64.5 32.8 79.3 43.2 1.8 47.1 25.6 2.1 10.2 34.6 72.9 75.8 28.8 5.0 204.7 14.2 16.6 40.3 40.5 39.1 18.4 11.9 61.7 7.4 28.6 28.2 7.4 60.9 10.3 16.2 45.6 4.6 23.1 33.0 48.9 21.3 5.3 10.7 86.8 60.7 55.8 10.5 18.2 26.0 39.9 98.4 69.3 45.3 71.5 5.9 3.7 4.3 49.9 3.3 94.7 0.1 0.2 0.2 1.5 0.0 0.1 0.7 0.6 1.5 0.1 0.5 0.3 0.4 0.5 0.1 0.7 0.1 0.0 0.6 25.4 16.6 28.2 35.9 21.2 38.5 25.7 14.2 29.9 7.3 35.0 46.4 40.0 48.1 33.3 28.4 0.5 12.6 12.3 8.1 5.7 5.7 5.0 7.4 8.4 38.6 15.3 66.2 141.8 31.8 9.2 0.1 50.9 50.6 203.7 18.5 4.8 25.3 0.0 4.8 15.8 63.6 6.4 11.8 2.0 15.6 3.8 0.9 25.4 16.6 25.7 1.7 14.8 2.1 2.0 6.6 10.2 430.5 12.2 24.7 28.4 16.9 1.1 10.6 15.5 27.2 28.9 67.1 1.2 22.6 0.8 13.8 34.7 51.4 14.9 165.5 19.7 10.3 16.5 7.7 9.9 1.0 8.2 19.4 5.8 10.5 0.9 7.9 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLHDC3 "dJ20C7.3, hPeas, PEAS" ENSG00000124702 "Kelch domain containing 3" Q9BQ90 6 43014103-43021298 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 395.9" "Group enriched" "Detected in all" 5 "Early spermatids: 552.0;Late spermatids: 1588.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030131, HPA030132, HPA030133, HPA030134" Uncertain Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA030131: AB_10599712, HPA030132: AB_10600880, HPA030133: AB_10611532, HPA030134: AB_10601350" "unprognostic (3.85e-2)" "prognostic favorable (9.15e-4)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (9.97e-3)" "unprognostic (2.80e-1)" "unprognostic (2.09e-3)" "unprognostic (1.05e-2)" "unprognostic (5.09e-2)" "unprognostic (1.58e-3)" "prognostic favorable (9.08e-4)" "unprognostic (6.34e-2)" "unprognostic (2.88e-2)" "unprognostic (8.73e-2)" "unprognostic (9.78e-2)" "unprognostic (2.88e-1)" "unprognostic (1.52e-1)" 52.5 64.9 161.4 33.9 170.8 48.6 52.7 144.2 203.3 48.5 139.0 75.0 40.1 44.5 56.3 49.5 53.0 37.4 105.7 178.2 143.8 53.2 73.0 43.2 45.4 150.6 153.9 55.6 51.1 54.6 68.8 59.2 156.5 56.8 40.7 48.2 60.6 47.8 395.9 51.4 48.6 43.3 140.5 54.0 64.8 192.2 158.6 67.1 49.7 203.9 44.8 49.8 46.2 157.1 119.1 36.0 117.1 197.3 79.0 59.4 83.8 52.6 67.7 100.7 109.4 104.5 60.6 117.0 58.7 77.3 37.8 61.6 126.1 67.8 68.5 62.8 171.3 146.0 102.1 109.7 77.4 86.5 99.7 95.8 67.1 77.6 45.2 77.9 98.7 131.1 180.7 80.9 38.4 147.3 142.3 148.9 153.4 297.3 38.0 137.2 86.0 141.4 62.3 67.9 216.1 168.8 55.8 63.2 93.1 75.7 109.8 247.6 58.8 45.7 83.9 50.8 52.9 88.0 118.8 170.9 19.9 122.7 39.4 42.3 83.5 100.3 62.0 78.9 51.9 41.6 50.8 56.0 90.7 39.6 65.6 51.8 40.4 54.7 63.3 49.8 59.5 76.5 161.4 170.8 144.2 203.3 178.2 143.8 150.6 153.9 156.5 140.5 158.6 157.1 21.3 12.8 17.0 10.4 26.7 18.7 32.9 33.5 14.8 31.9 37.8 33.7 40.3 37.1 19.1 18.4 14.6 99.6 32.7 34.8 86.1 61.7 552.0 19.2 19.0 30.4 52.3 59.3 29.1 54.7 115.1 36.2 20.9 18.8 13.4 50.7 32.5 28.4 63.8 32.0 22.0 43.7 34.6 47.0 22.7 1588.3 44.7 31.8 33.8 11.2 54.7 55.4 55.6 11.6 14.8 46.3 44.3 59.0 31.7 44.4 72.6 55.3 16.9 25.9 52.6 30.4 32.2 180.8 35.6 22.8 20.6 107.0 28.3 71.4 53.7 36.7 KLHL33 ENSG00000185271 "Kelch like family member 33" A6NCF5 14 20425852-20436166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 29 "skeletal muscle: 73.3;tongue: 20.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 21 "dendritic cells: 5.8" "Cell line enriched" "Detected in single" 9 "REH: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049985, HPA056560" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA049985: , HPA056560: AB_2683174" "unprognostic (6.92e-2)" "unprognostic (6.39e-2)" "unprognostic (2.07e-1)" "unprognostic (4.81e-1)" "unprognostic (2.43e-1)" "unprognostic (2.26e-1)" "unprognostic (2.38e-3)" "unprognostic (1.60e-1)" "unprognostic (9.77e-2)" "unprognostic (1.25e-1)" "unprognostic (7.39e-2)" "unprognostic (4.15e-2)" "unprognostic (4.60e-2)" "unprognostic (7.43e-3)" "unprognostic (4.88e-3)" "unprognostic (3.32e-5)" "unprognostic (2.32e-1)" 0.9 0.3 0.5 0.2 0.5 0.2 0.6 1.5 0.6 1.2 0.3 0.8 0.3 1.4 1.0 0.9 0.8 0.8 1.0 0.4 0.5 0.5 0.1 0.4 0.6 0.4 0.6 1.2 0.2 0.5 0.2 0.2 0.4 1.0 0.3 0.3 0.5 1.0 73.3 0.1 0.5 0.5 0.1 0.6 0.3 0.4 0.6 1.0 0.4 20.2 0.6 0.5 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 5.8 0.0 0.1 0.5 0.5 1.5 0.6 0.4 0.5 0.4 0.6 0.4 0.1 0.6 0.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.5;brain: 21.3" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 286.2;Theca cells: 109.4" "Cancer enriched" "Detected in some" 8 "glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;GAMG: 18.2;HUVEC TERT2: 32.0;NTERA-2: 24.3;SuSa: 17.8;TIME: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Centriolar satellite" "HPA029192: AB_10602341" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "unprognostic (5.90e-2)" "unprognostic (1.71e-2)" "unprognostic (1.89e-2)" "unprognostic (5.21e-2)" "unprognostic (2.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (2.40e-4)" "unprognostic (1.05e-1)" "unprognostic (5.87e-2)" "unprognostic (7.25e-4)" 1.3 26.5 5.3 0.4 10.2 0.0 0.9 7.3 7.1 1.2 0.6 0.3 0.1 3.0 0.3 0.5 2.5 1.5 0.8 5.2 5.7 1.1 0.6 0.8 0.4 9.6 7.5 7.9 0.3 0.0 0.0 0.1 9.5 0.3 0.3 2.3 0.0 1.4 0.3 0.1 0.3 5.1 7.5 1.3 0.3 7.0 6.7 0.1 0.6 0.3 0.1 0.9 0.2 21.3 0.0 3.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.1 0.9 0.0 1.4 0.4 0.0 2.6 0.0 11.0 0.2 0.0 1.6 4.7 6.0 1.3 11.6 32.0 0.0 0.2 2.5 8.1 0.0 0.0 0.0 24.3 0.1 5.7 0.0 8.9 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 17.8 0.0 0.1 34.4 0.0 5.6 0.0 0.5 0.2 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 10.2 7.3 7.1 5.2 5.7 9.6 7.5 9.5 7.5 6.7 21.3 1.7 0.0 0.0 2.0 0.0 0.1 0.0 0.1 0.0 3.6 0.0 0.0 1.5 0.0 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.7 0.2 0.1 15.0 0.0 0.0 44.4 0.0 0.0 4.4 0.0 0.1 0.0 4.5 14.3 0.2 0.1 0.0 6.6 0.0 0.0 0.3 0.3 1.5 0.9 0.1 0.0 4.7 0.0 1.5 0.0 36.2 286.2 0.1 0.0 1.5 0.1 0.0 0.0 3.4 2.2 4.1 0.0 1.2 0.5 0.4 0.4 0.0 0.3 0.0 0.7 109.4 0.0 0.0 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 284.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 39.1;Basal squamous epithelial cells: 21.6;Endometrial ciliated cells: 7.2;Glandular and luminal cells: 10.9;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 7.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049550, HPA055194" Enhanced NA NA 440000000 "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA049550: AB_2680813, HPA055194: AB_2682733" "unprognostic (3.92e-2)" "unprognostic (3.50e-1)" "unprognostic (3.30e-1)" "unprognostic (5.51e-2)" "unprognostic (7.71e-2)" "unprognostic (4.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (4.07e-1)" "unprognostic (4.26e-2)" "unprognostic (1.65e-1)" 3.8 0.0 0.4 0.0 0.1 0.0 0.5 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 4.7 284.4 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 39.1 0.3 2.9 21.6 0.0 0.2 0.6 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.0 10.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.4 16.5 7.7 0.0 0.1 0.2 0.0 0.0 KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 136.1;Club cells: 109.6;Ionocytes: 114.0;Langerhans cells: 190.5;Macrophages: 122.9;monocytes: 248.0;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cell line enhanced" "Detected in many" "A549: 185.2;GAMG: 298.5;HeLa: 195.5;Hep G2: 128.3;hTEC/SVTERT24-B: 106.5;U-87 MG: 314.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 5.2 4.0 2.4 24.4 2.1 10.8 30.8 2.7 4.5 4.0 3.6 2.4 1.1 2.5 1.3 6.7 1.2 9.8 1.2 2.0 1.6 18.6 88.4 13.5 15.0 2.8 1.7 0.4 0.9 0.8 1.2 7.3 3.3 0.9 2.9 1.5 1.8 0.7 0.7 1.3 3.0 4.8 0.5 8.9 5.8 16.6 6.6 3.9 2.3 0.3 28.9 51.5 3.4 2.1 0.2 185.2 0.3 0.4 0.4 0.6 0.5 0.4 5.1 0.2 0.2 3.3 2.7 11.9 0.5 0.1 298.5 0.7 0.1 0.2 0.2 0.6 0.2 4.3 195.5 128.3 2.4 0.4 0.8 17.3 15.0 106.5 0.6 0.2 0.2 0.3 0.5 1.1 1.7 96.7 0.2 11.8 0.7 0.2 0.9 0.2 0.9 0.4 3.2 96.0 0.5 0.3 102.2 15.2 1.0 1.0 50.9 26.5 1.5 5.9 0.5 89.1 0.3 0.7 0.3 0.3 314.5 22.2 0.6 0.7 109.4 2.4 0.5 142.7 0.4 73.6 0.6 0.3 111.2 51.3 0.5 0.3 5.8 1.8 123.4 77.7 0.6 49.2 2.4 2.1 2.7 4.5 2.0 1.6 2.8 1.7 3.3 0.5 6.6 2.1 3.0 3.2 2.7 0.7 46.8 4.0 0.5 136.1 0.0 0.5 5.8 0.9 1.6 7.2 109.6 3.7 4.2 3.3 16.1 0.7 5.9 14.5 46.3 1.5 1.1 5.1 0.0 2.5 1.3 9.5 2.3 1.8 20.4 15.7 0.0 0.0 2.5 49.1 38.8 10.1 0.9 0.0 114.0 64.7 190.5 42.8 1.8 122.9 1.8 29.0 248.0 0.2 1.0 0.5 0.8 59.6 1.1 0.4 5.1 1.1 0.0 44.4 21.1 0.6 6.6 0.5 3.9 47.8 8.0 1.5 3.1 104.7 2.2 0.1 1.0 22.6 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAPTM4B LC27 ENSG00000104341 "Lysosomal protein transmembrane 4 beta" Q86VI4 8 97775057-97853013 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 380.1" "Cell type enhanced" "Detected in all" "Granulosa cells: 348.5;Rod photoreceptor cells: 575.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;T-cells: 1.4" "Cell line enhanced" "Detected in many" "HEL: 611.7;RPTEC TERT1: 549.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020782, HPA068830" Uncertain Approved "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "CAB020782: , HPA068830: AB_2686044" "prognostic unfavorable (5.63e-4)" "unprognostic (1.91e-2)" "unprognostic (7.04e-2)" "unprognostic (6.83e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.70e-4)" "prognostic unfavorable (2.70e-6)" "unprognostic (9.25e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-1)" "unprognostic (7.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-1)" "unprognostic (3.14e-1)" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" 24.2 43.2 30.2 18.0 29.7 5.3 42.9 37.3 29.6 50.1 78.2 34.0 79.7 71.0 29.3 33.7 67.5 46.3 220.9 23.6 35.3 67.3 25.3 39.6 13.7 42.1 36.1 45.1 28.8 185.5 20.3 28.2 39.5 29.2 32.9 380.1 32.8 44.9 153.7 43.9 43.0 47.8 45.2 38.3 32.2 62.5 44.2 8.6 43.0 117.0 20.2 41.0 28.5 50.1 219.2 170.8 171.9 350.3 80.2 61.0 108.1 98.0 50.1 222.9 188.6 103.1 168.0 1.0 378.0 73.5 75.2 241.2 208.8 94.8 242.9 1.5 282.4 611.7 130.6 169.0 66.1 0.3 101.5 83.8 71.0 130.8 66.0 75.1 29.1 69.5 375.7 0.8 92.4 164.1 54.5 34.1 318.8 116.5 106.5 0.6 90.5 0.7 549.4 100.9 172.8 287.1 133.6 63.8 159.4 188.0 154.3 83.7 8.1 47.7 92.0 99.0 70.7 22.4 68.8 2.2 60.8 0.5 144.9 3.3 0.1 0.0 0.5 0.0 1.4 0.3 0.4 0.3 0.1 0.1 0.8 0.9 0.1 0.3 0.0 0.1 0.2 0.2 30.2 29.7 37.3 29.6 23.6 35.3 42.1 36.1 39.5 45.2 44.2 50.1 60.5 102.5 56.1 8.5 4.9 55.2 68.1 63.9 89.4 195.9 59.8 55.6 208.1 82.9 30.9 106.7 223.1 26.6 3.9 17.9 39.2 244.5 7.1 70.6 59.6 77.4 35.4 36.6 15.0 123.6 33.2 72.2 19.4 105.6 12.7 348.5 132.8 32.6 8.6 134.6 36.6 29.6 59.0 3.7 10.1 8.6 23.9 6.6 42.7 4.7 2.8 135.0 1.0 19.1 20.1 72.1 34.4 30.9 1.7 77.0 95.9 62.1 10.5 575.3 59.2 62.6 75.4 7.4 35.8 45.1 44.3 14.1 10.2 119.9 52.1 86.4 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86668507-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 1423.0;skeletal muscle: 2945.6;tongue: 1809.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1825.0" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.7;melanoma: 2.5;prostate cancer: 3.6;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 3.0;hTERT-RPE1: 3.3;SCLC-21H: 4.9;SK-MEL-30: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048955 Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 750000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: AB_2680568" "unprognostic (1.60e-1)" "unprognostic (9.01e-2)" "unprognostic (4.87e-2)" "unprognostic (6.92e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-2)" "unprognostic (7.61e-2)" "unprognostic (2.54e-3)" "unprognostic (3.55e-2)" "unprognostic (4.72e-4)" "unprognostic (3.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.16e-1)" 11.1 1.4 12.8 2.8 39.6 0.4 6.5 29.8 29.0 10.1 0.1 36.2 2.4 15.1 4.9 54.5 17.3 3.1 1423.0 14.7 23.3 2.0 0.8 5.1 0.5 55.5 36.9 6.4 1.3 0.5 2.4 2.7 46.2 38.1 5.3 0.7 20.8 25.2 2945.6 4.8 8.8 23.7 26.4 0.6 9.0 4.7 38.4 0.7 5.2 1809.4 0.3 7.0 10.3 78.4 0.1 0.1 0.2 1.7 0.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.4 0.7 0.0 0.0 0.0 0.9 3.0 0.2 0.0 0.0 3.3 0.0 0.3 0.1 1.0 0.0 0.8 0.2 0.1 0.2 0.2 0.2 0.0 1.1 0.0 0.0 0.6 4.9 0.9 0.2 0.1 2.4 0.7 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 39.6 29.8 29.0 14.7 23.3 55.5 36.9 46.2 26.4 38.4 78.4 1.5 0.0 0.0 1.0 0.0 1.0 0.5 0.2 0.0 1.5 0.2 0.3 1825.0 0.0 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.0 23.4 0.1 0.4 15.5 0.0 0.0 4.5 1.1 0.0 31.5 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.0 2.6 0.0 4.1 0.0 1.2 19.6 11.1 0.5 1.8 1.9 0.0 0.7 0.0 1.5 245.1 0.1 0.0 6.8 0.0 0.3 0.0 0.1 0.1 4.1 39.5 48.0 54.9 1.0 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.7;choroid plexus: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 242.9;Excitatory neurons: 57.1;Inhibitory neurons: 74.7;Oligodendrocyte precursor cells: 28.6" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;CACO-2: 2.0;NTERA-2: 6.1;SuSa: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" 0.5 1.8 26.8 0.1 31.5 0.0 0.2 23.8 39.7 0.1 44.7 4.0 0.5 0.1 0.0 4.3 0.1 1.0 0.5 29.2 22.6 0.0 2.7 0.0 0.0 29.9 24.2 0.0 0.2 0.0 7.6 0.0 32.9 0.7 2.6 0.4 0.1 0.5 5.9 0.3 1.5 0.6 23.7 0.0 1.8 0.4 26.7 0.0 0.2 3.6 0.1 0.9 0.3 25.2 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 31.5 23.8 39.7 29.2 22.6 29.9 24.2 32.9 23.7 26.7 25.2 0.2 0.0 0.0 242.9 0.0 0.3 0.4 0.0 0.0 0.5 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 57.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 74.7 0.0 0.0 0.0 0.4 1.6 1.5 0.0 0.0 10.3 0.0 0.1 0.0 28.6 3.9 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.2 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1448.9;Macrophages: 346.1;Syncytiotrophoblasts: 416.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 898.6;U-266/70: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 173.7 44.4 37.6 82.2 38.6 20.6 69.7 31.7 60.8 52.6 51.2 102.5 110.4 30.8 36.8 64.5 36.6 145.8 85.3 40.0 40.3 205.9 111.1 107.3 177.0 35.6 37.3 33.0 37.9 247.0 24.9 262.1 42.4 51.9 105.9 19.7 56.4 32.2 50.4 32.7 97.6 65.0 35.9 202.2 107.0 29.8 62.8 52.8 93.2 50.4 54.9 144.7 52.1 49.4 33.2 47.5 30.8 57.4 94.3 76.0 108.4 70.3 67.0 71.7 84.2 36.9 58.6 18.2 101.5 116.5 44.3 81.5 0.0 60.8 33.7 1.6 36.2 1.2 24.4 42.8 27.7 1.0 2.7 54.2 29.1 68.4 39.4 21.3 82.1 33.7 7.4 150.9 5.2 45.2 8.9 1.2 15.1 208.2 32.1 8.4 27.1 898.6 59.2 129.1 33.6 23.2 97.9 59.4 53.0 66.8 43.9 0.6 47.2 35.3 44.8 64.5 21.8 462.5 58.0 25.0 20.0 0.2 69.1 1.9 1.6 0.1 0.8 3.1 1.6 17.0 5.1 1.3 19.3 14.5 15.2 9.0 1.6 3.7 1.0 209.2 9.7 7.0 37.6 38.6 31.7 60.8 40.0 40.3 35.6 37.3 42.4 35.9 62.8 49.4 34.9 57.7 128.0 8.8 33.9 23.1 37.5 36.0 22.2 10.6 31.2 37.6 29.8 42.9 48.1 31.3 93.8 181.8 24.5 64.2 9.8 61.3 1.3 79.4 23.5 38.3 36.5 22.7 19.2 50.6 140.2 63.8 73.4 177.7 8.8 17.6 276.3 46.4 1448.9 13.5 41.0 31.1 95.6 317.6 89.0 3.3 30.4 346.1 48.0 27.2 37.5 23.6 2.1 10.6 15.2 50.5 57.1 57.9 24.7 44.6 163.4 220.4 20.9 19.8 19.7 40.4 62.1 19.9 17.6 22.3 17.5 416.3 8.2 15.1 48.3 44.7 LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 9.0;Cardiomyocytes: 10.5;dendritic cells: 6.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 15.4;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.4" "Cell line enhanced" "Detected in some" "A549: 17.4;CAPAN-2: 15.4;HaCaT: 8.3;HeLa: 3.9" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" 1.1 0.2 2.3 0.4 5.4 1.4 5.1 8.2 1.5 3.7 0.3 1.4 0.1 1.2 2.2 5.0 8.8 6.2 14.7 1.0 7.2 0.8 2.1 3.4 0.8 14.7 7.6 1.8 0.2 0.0 17.5 0.3 8.0 5.9 0.7 0.0 5.3 1.4 0.3 4.1 1.3 0.3 6.1 6.7 0.6 7.2 9.8 0.3 5.1 0.5 0.3 2.9 3.8 2.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.6 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.0 0.0 1.7 9.1 0.0 0.0 0.7 4.8 0.0 0.4 0.0 0.0 0.5 3.4 2.3 5.4 8.2 1.5 1.0 7.2 14.7 7.6 8.0 6.1 9.8 2.0 0.1 0.0 0.0 2.6 0.2 1.3 3.6 0.5 23.3 0.0 1.5 9.0 10.5 0.0 0.6 0.0 0.0 0.9 6.0 0.8 0.0 0.0 3.1 0.0 0.0 0.2 0.0 0.4 1.0 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.4 0.2 0.1 0.0 0.8 1.6 0.0 0.6 0.3 4.1 0.0 0.2 0.0 1.9 0.0 0.0 4.1 0.0 0.2 0.0 0.7 0.0 2.5 0.2 0.1 0.1 0.0 0.0 0.0 0.0 5.6 5.5 3.3 0.3 0.1 0.8 4.3 0.0 2.7 0.9 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 61.1;Kupffer cells: 103.4;Macrophages: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" 17.9 10.3 0.2 1.7 0.5 0.9 7.2 0.3 1.0 1.6 1.3 6.1 4.6 1.1 0.8 1.8 4.4 2.8 5.1 0.2 0.2 1.6 7.1 5.3 1.8 0.5 0.3 1.3 0.8 0.3 0.7 4.8 0.4 0.6 4.8 0.1 2.9 0.6 1.8 2.3 6.8 2.4 0.2 49.1 2.5 1.1 1.0 1.0 1.4 1.3 0.7 4.2 1.2 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.5 0.3 1.0 0.2 0.2 0.5 0.3 0.4 0.2 1.0 1.1 0.5 0.0 1.1 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 1.7 0.0 0.1 0.2 0.0 2.7 0.0 0.0 0.4 0.7 0.0 0.1 0.0 0.1 8.6 0.9 61.1 0.0 0.0 0.0 0.0 103.4 9.8 1.8 0.0 40.1 1.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.5 0.0 0.1 0.3 1.1 0.8 0.4 0.5 0.0 0.0 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.3;Early spermatids: 107.2;Excitatory neurons: 135.5;Inhibitory neurons: 93.1;Late spermatids: 76.9;Spermatocytes: 61.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;ASC TERT1: 31.4;HAP1: 25.2;HDLM-2: 29.6;HL-60: 29.1;NB-4: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" 5.0 3.1 5.5 2.4 6.5 27.9 5.4 22.2 8.0 7.9 1.0 1.9 0.5 8.5 0.5 0.9 3.7 4.0 6.3 6.4 6.0 8.7 17.7 5.1 2.6 1.9 6.9 3.7 0.5 0.9 6.0 5.3 3.1 1.8 0.6 26.6 0.8 0.7 1.0 0.7 2.1 4.6 2.3 4.6 1.1 7.1 6.9 0.7 4.2 2.5 1.2 3.9 4.6 3.6 0.0 0.6 5.0 0.0 21.3 31.4 0.0 12.8 5.9 5.1 1.1 9.9 0.0 0.0 0.0 4.9 0.1 0.0 25.2 0.0 1.5 29.6 7.8 0.0 0.2 15.6 2.6 29.1 0.2 7.8 0.0 0.5 0.5 1.2 4.1 0.0 0.0 0.0 2.3 0.3 0.0 27.0 4.7 0.3 0.1 0.0 18.7 0.0 2.9 4.1 10.2 0.0 0.0 0.0 0.1 0.3 1.1 15.5 0.0 4.0 1.5 2.1 0.1 4.4 0.0 0.0 0.4 0.0 0.2 18.8 5.2 15.8 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 29.8 0.0 0.2 0.0 0.1 1.2 5.5 6.5 22.2 8.0 6.4 6.0 1.9 6.9 3.1 2.3 6.9 3.6 4.8 22.4 5.8 18.6 0.0 0.8 4.8 0.0 0.0 77.3 10.8 3.4 22.8 8.6 0.6 25.8 2.1 0.4 0.2 0.3 9.8 1.3 107.2 1.9 8.9 1.9 1.8 0.4 135.5 0.2 0.1 4.9 0.0 3.5 0.0 0.1 1.8 21.5 2.5 30.3 93.1 0.5 0.0 5.2 0.7 76.9 4.7 4.2 0.0 9.4 6.5 42.6 0.0 23.1 2.7 0.0 1.2 1.5 0.4 2.0 20.1 26.5 0.7 11.2 13.1 5.0 19.2 61.3 1.3 0.0 0.4 0.7 0.6 3.5 1.1 1.8 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 6.8 5.3 4.5 7.8 4.7 14.3 3.0 4.5 5.3 5.1 3.8 7.3 4.0 7.4 1.7 3.2 4.9 6.5 8.2 4.5 5.6 2.0 1.5 4.6 4.1 7.0 5.0 2.9 1.1 1.7 2.7 15.9 6.3 3.3 3.7 4.9 1.6 4.0 1.3 2.0 3.9 8.1 5.6 8.9 2.7 2.6 7.0 1.4 2.2 1.5 2.3 5.2 4.0 7.3 1.6 0.3 21.8 3.7 17.1 20.6 4.5 71.0 143.4 33.8 31.8 25.6 1.3 0.1 0.9 73.1 1.6 1.1 2.8 1.8 19.8 110.7 1.0 17.6 1.8 0.2 5.7 0.6 16.7 22.6 0.2 90.6 3.8 12.0 0.7 0.8 0.8 2.8 6.4 4.1 0.2 6.5 12.0 0.8 0.7 2.0 3.1 0.3 0.3 1.2 11.2 12.8 0.6 1.1 14.7 3.2 2.3 1.3 0.3 245.9 8.2 1.4 0.9 1.4 0.5 0.1 92.5 6.8 549.6 0.1 6.0 0.3 0.0 11.7 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 2.5 0.0 9.3 0.4 0.0 2.6 4.5 4.7 4.5 5.3 4.5 5.6 7.0 5.0 6.3 5.6 7.0 7.3 0.9 0.0 0.5 14.0 0.3 0.9 0.2 0.6 0.6 0.9 0.4 0.8 0.3 1.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.2 4.8 1.2 0.0 0.4 0.4 0.0 1.5 7.1 0.0 0.5 1.3 0.7 0.4 0.1 17.9 1.7 4.2 0.1 0.0 12.5 2.5 0.7 5.0 12.3 0.0 30.0 4.8 10.6 1.0 11.6 0.6 0.3 0.0 4.5 0.1 0.3 0.0 0.1 0.0 0.9 19.7 1.6 5.3 0.6 0.8 0.1 0.1 0.8 0.4 0.2 0.0 0.2 LPCAT2 "AGPAT11, AYTL1, FLJ20481, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.3;thyroid gland: 86.3" "Cell type enhanced" "Detected in many" "granulocytes: 173.3;Microglial cells: 224.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 23.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.4;eosinophil: 199.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 115.9;HaCaT: 89.2;HL-60: 103.0;HMC-1: 161.7;hTERT-RPE1: 162.9;WM-115: 117.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favorable (3.43e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" 9.8 9.0 5.6 14.4 7.7 88.3 12.2 10.6 5.2 14.0 10.7 9.0 7.4 18.5 36.7 7.8 8.8 10.5 5.7 4.8 8.5 10.9 3.9 10.4 5.0 13.7 8.5 15.8 5.4 13.6 1.0 16.0 15.9 7.0 9.3 7.7 8.4 28.6 2.2 12.0 9.1 15.0 12.7 11.8 9.0 4.1 7.9 3.5 86.3 5.8 4.0 9.5 7.5 22.4 33.5 4.2 3.5 0.3 10.8 4.1 5.6 14.1 13.5 6.8 6.9 7.5 115.9 0.0 46.6 19.9 5.5 89.2 2.2 19.4 10.9 9.1 9.6 34.2 10.2 17.3 4.1 103.0 161.7 2.1 19.2 7.5 6.3 162.9 53.5 1.8 1.5 0.4 11.6 2.1 0.0 41.8 5.1 9.5 0.4 10.4 3.8 5.1 6.8 12.9 2.2 25.3 27.1 10.8 19.9 15.8 4.6 25.8 60.3 0.3 0.1 6.9 9.6 0.6 0.2 0.2 0.5 49.4 117.8 151.4 17.5 199.2 0.0 27.4 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 47.0 0.0 39.1 0.7 0.0 6.5 5.6 7.7 10.6 5.2 4.8 8.5 13.7 8.5 15.9 12.7 7.9 22.4 68.6 6.4 25.7 2.9 1.1 15.4 37.2 68.3 17.1 5.5 8.8 33.9 2.2 4.3 22.3 68.0 10.4 0.7 3.3 7.0 1.9 8.3 1.7 6.4 4.8 41.0 1.2 9.7 8.1 9.7 7.5 20.7 10.2 13.9 173.3 0.4 12.1 2.0 36.5 0.0 11.7 12.2 18.3 71.9 57.7 3.1 16.4 74.4 17.8 224.9 40.6 24.0 0.0 4.5 66.5 32.8 23.0 12.8 1.0 9.0 3.4 3.5 8.1 5.3 0.0 20.0 4.2 49.6 24.0 14.2 15.3 1.9 5.6 7.0 11.6 17.6 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.2;Gastric mucus-secreting cells: 131.5;Urothelial cells: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 108.5;OE19: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 19.7 6.2 18.0 12.2 18.3 6.7 17.8 12.8 38.5 21.6 4.0 44.8 30.9 14.4 9.4 36.1 18.7 17.0 26.0 18.8 21.2 9.3 3.4 10.0 9.7 26.2 12.8 11.8 10.2 7.1 11.8 5.1 26.0 11.1 35.9 4.9 11.8 8.8 8.3 18.6 31.2 16.7 8.5 16.3 39.7 3.3 18.1 8.7 8.4 8.0 11.2 22.2 28.9 21.6 13.7 31.9 15.7 12.6 41.4 41.9 7.5 18.8 31.5 17.6 24.0 11.6 36.0 12.4 38.4 26.3 41.3 108.5 13.8 35.5 7.8 25.2 8.2 12.5 13.6 11.3 8.5 13.5 12.3 31.3 15.8 16.6 21.4 40.6 29.0 22.1 8.3 23.6 33.1 13.3 11.9 26.1 15.7 113.7 26.0 14.7 17.6 25.1 38.7 32.4 12.6 9.5 11.3 14.9 7.3 18.2 11.5 17.9 36.4 32.5 19.6 51.8 18.3 28.5 23.9 4.3 24.3 37.0 7.6 0.1 0.8 3.6 2.7 1.1 6.6 1.6 3.2 4.2 1.3 2.3 1.8 1.7 3.5 1.7 1.4 4.6 5.6 0.8 18.0 18.3 12.8 38.5 18.8 21.2 26.2 12.8 26.0 8.5 18.1 21.6 31.0 25.6 5.9 8.8 13.1 4.8 7.8 35.5 15.4 15.5 5.8 8.3 12.8 25.8 63.1 9.2 4.2 4.9 15.7 85.2 1.9 11.6 0.0 7.1 7.8 31.9 25.3 9.2 57.5 9.8 17.1 9.6 131.5 10.1 12.0 5.5 23.6 0.7 7.9 10.1 53.3 58.0 24.4 8.1 9.7 1.2 15.5 6.3 8.8 9.4 5.7 1.7 9.2 12.5 7.2 43.1 83.4 6.8 29.1 9.7 58.7 2.8 40.7 5.9 13.1 5.1 11.9 2.5 8.1 20.3 6.1 2.5 19.9 8.6 71.8 129.9 LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 89.2;Inhibitory neurons: 117.6;Microglial cells: 183.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 37.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" 15.1 5.0 4.7 10.7 4.7 8.9 14.6 37.1 6.2 15.9 4.2 15.2 7.9 16.3 7.7 10.0 11.8 12.6 8.4 5.7 6.1 14.9 12.2 13.8 16.3 6.5 7.0 10.1 5.6 5.4 5.8 18.2 7.8 10.8 10.0 10.3 10.0 12.0 3.9 17.9 11.6 17.6 7.9 14.6 13.0 4.6 6.8 18.5 6.5 7.5 15.7 13.5 9.7 7.5 7.4 10.4 9.2 9.6 6.6 12.5 23.6 12.4 16.1 15.0 14.2 23.5 12.3 23.4 3.4 11.7 9.8 10.4 7.1 12.5 21.6 24.2 6.6 21.0 4.3 11.1 8.2 13.8 34.5 7.9 9.7 13.9 16.8 12.3 13.1 15.6 4.2 6.9 11.2 14.2 14.8 17.3 5.2 46.3 5.5 8.0 10.0 6.3 28.1 7.5 14.5 14.6 7.0 6.8 18.8 16.2 5.3 18.3 12.5 8.8 6.0 11.0 11.9 1.3 3.7 10.6 10.3 11.9 10.8 0.6 0.9 0.9 1.5 0.7 0.8 2.2 1.1 1.0 0.8 2.7 0.8 0.9 0.3 2.5 0.5 1.0 0.8 0.9 4.7 4.7 37.1 6.2 5.7 6.1 6.5 7.0 7.8 7.9 6.8 7.5 61.5 6.4 6.1 24.8 26.7 37.5 10.5 6.2 27.3 8.3 12.0 11.8 7.2 17.2 6.5 22.0 22.9 13.4 8.4 6.8 9.8 8.3 1.6 5.4 6.5 32.5 1.8 9.9 89.2 4.2 12.7 14.3 18.8 13.7 27.9 2.8 17.5 9.3 13.4 3.3 117.6 10.6 8.2 16.9 30.7 2.1 13.1 12.3 30.2 183.6 8.4 5.5 8.2 64.8 9.7 13.5 5.5 17.0 12.4 12.9 8.0 8.4 2.6 8.5 13.1 15.6 18.6 1.7 4.1 15.9 33.2 9.7 14.7 15.3 7.8 9.2 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRRC10B ENSG00000204950 "Leucine rich repeat containing 10B" A6NIK2 11 61508749-61511018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 42.4;fallopian tube: 28.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 49.3;Muller glia cells: 9.5;Respiratory ciliated cells: 37.2;Sertoli cells: 19.7;Smooth muscle cells: 20.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.8" "Region enhanced" "Detected in many" "basal ganglia: 42.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 9.7;RH-30: 10.5;SCLC-21H: 5.4" "Region enriched" "Detected in many" 7 "basal ganglia: 222.5" "Group enriched" "Detected in many" 5 "basal ganglia: 30.9;hippocampal formation: 24.2" HPA047619 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Nucleoli "HPA047619: AB_2680106" "unprognostic (9.95e-2)" "unprognostic (2.67e-2)" "unprognostic (4.92e-2)" "unprognostic (1.26e-2)" "unprognostic (2.11e-1)" "unprognostic (1.32e-1)" "unprognostic (6.10e-2)" "unprognostic (9.22e-2)" "unprognostic (4.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.21e-3)" "unprognostic (2.52e-2)" "unprognostic (5.27e-4)" "unprognostic (5.07e-2)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (6.63e-2)" 3.7 0.9 11.1 0.4 42.4 0.0 2.9 0.5 11.2 5.9 3.6 2.2 0.3 4.9 1.9 0.5 28.7 0.3 1.7 13.5 5.2 2.2 0.1 4.9 0.0 4.0 4.0 2.3 1.3 2.2 33.7 0.5 2.1 1.6 0.3 0.1 1.3 0.5 0.7 0.9 1.4 1.6 3.1 0.4 2.9 5.9 7.9 2.7 1.6 0.9 0.0 1.1 2.5 3.4 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.0 10.5 0.0 0.0 0.0 5.4 0.5 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 42.4 0.5 11.2 13.5 5.2 4.0 4.0 2.1 3.1 7.9 3.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.6 0.4 1.1 0.0 3.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 3.2 49.3 0.5 0.4 4.2 0.0 1.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 6.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 37.2 0.2 19.7 0.7 20.6 0.8 1.1 0.0 0.3 0.1 0.1 0.2 0.1 0.1 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC3 "C21orf102, C21orf30, DKFZP434C128, LRRC3DN" ENSG00000160233 "Leucine rich repeat containing 3" Q9BY71 21 44455510-44462196 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.7;U-2 OS: 6.3" "Low region specificity" "Detected in all" HPA017975 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "HPA017975: AB_1853307" "unprognostic (1.36e-2)" "unprognostic (5.48e-3)" "unprognostic (1.49e-2)" "unprognostic (2.10e-4)" "unprognostic (1.55e-1)" "unprognostic (1.74e-2)" "unprognostic (7.20e-3)" "unprognostic (2.59e-1)" "unprognostic (4.61e-1)" "unprognostic (7.43e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-5)" "unprognostic (6.44e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-2)" "unprognostic (6.66e-3)" 1.9 1.4 0.8 0.7 0.5 0.6 1.5 0.2 0.7 1.4 0.3 6.6 1.7 1.3 0.4 1.1 1.5 2.2 1.9 0.6 2.0 0.7 15.5 1.6 0.5 0.6 0.9 3.4 0.7 0.3 1.3 0.9 0.6 0.8 0.8 0.3 1.0 0.6 0.4 1.8 1.6 1.5 0.2 1.1 3.8 1.7 1.2 0.5 0.6 1.0 0.3 2.0 1.3 0.6 0.5 0.4 3.5 2.9 0.0 0.0 8.7 1.5 0.0 0.1 0.0 1.3 1.2 0.0 2.6 0.7 1.9 0.1 1.7 0.0 0.0 0.2 3.8 0.0 0.4 4.0 0.6 0.0 2.3 1.1 1.4 0.0 0.0 0.0 1.4 0.6 0.3 4.5 0.0 1.3 0.5 0.2 0.9 4.5 1.4 1.9 0.0 1.5 0.1 0.1 2.8 3.2 1.3 0.3 0.6 1.9 0.8 1.9 2.8 0.0 6.3 0.0 0.0 2.5 5.2 0.0 0.0 1.6 0.5 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.2 0.7 0.6 2.0 0.6 0.9 0.6 0.2 1.2 0.6 2.6 0.0 1.5 0.0 0.8 0.6 1.1 0.0 3.4 1.1 0.6 0.9 2.0 1.5 0.0 1.8 0.0 0.2 0.3 1.6 0.0 0.3 0.3 0.2 0.4 0.6 4.2 2.7 0.0 0.4 6.6 2.5 1.5 0.9 1.3 2.4 1.1 30.7 2.5 0.0 0.1 1.8 0.0 2.5 0.5 1.5 0.6 1.1 0.0 0.0 3.2 1.4 1.0 0.0 0.1 1.7 0.3 0.7 0.2 1.3 1.8 0.0 0.0 0.0 0.0 0.8 1.4 0.9 2.0 0.6 0.6 0.3 0.8 0.3 1.7 0.7 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC39 "MGC14816, myomasp" ENSG00000122477 "Leucine rich repeat containing 39" Q96DD0 1 100148448-100178273 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 107.0;retina: 117.9;skeletal muscle: 431.0;tongue: 172.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 96.4;Cone photoreceptor cells: 60.5;Early spermatids: 204.8;Hofbauer cells: 76.4;Inhibitory neurons: 62.2;Rod photoreceptor cells: 74.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077159 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA077159: AB_2732333" "unprognostic (7.68e-2)" "unprognostic (3.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-1)" "unprognostic (6.40e-2)" "unprognostic (1.27e-1)" "unprognostic (4.07e-3)" "unprognostic (1.58e-2)" "unprognostic (1.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (3.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (8.17e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-4)" 2.2 9.8 3.5 1.5 3.6 1.5 1.9 2.8 4.7 1.6 1.1 1.8 1.0 1.4 1.4 4.2 1.7 1.1 107.0 2.8 3.7 1.7 2.6 1.7 2.4 3.8 2.9 1.6 1.6 5.3 2.3 4.2 2.5 4.2 0.6 117.9 2.9 0.5 431.0 3.8 1.7 0.7 1.8 2.3 1.6 6.5 4.2 1.1 1.9 172.9 0.9 1.7 1.3 3.6 0.4 0.5 1.8 2.4 0.4 0.8 1.5 0.8 0.3 0.3 0.7 0.1 1.1 2.0 0.9 0.3 0.4 1.1 0.2 0.2 0.7 0.3 1.7 0.9 2.4 0.4 0.2 0.6 1.1 1.5 0.3 0.3 0.1 0.5 0.3 1.5 0.9 1.7 0.5 0.3 1.0 2.4 0.8 0.5 0.6 1.0 0.8 0.8 0.3 0.6 0.7 2.5 0.5 0.7 6.7 0.6 0.6 1.4 0.5 1.0 0.9 1.3 1.6 3.2 1.6 0.7 1.7 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.8 4.7 2.8 3.7 3.8 2.9 2.5 1.8 4.2 3.6 0.3 0.0 1.3 6.8 0.4 0.1 0.1 0.0 0.0 13.1 0.3 0.1 96.4 0.0 0.0 0.0 60.5 0.5 0.3 0.3 0.0 0.2 204.8 0.2 0.5 1.8 0.0 0.0 14.6 0.6 0.6 3.8 0.0 0.5 1.3 0.2 0.7 0.2 76.4 18.5 62.2 0.0 0.0 0.3 0.0 21.7 2.1 8.0 0.0 1.9 0.8 8.1 1.0 5.5 10.2 0.3 0.1 0.4 0.5 0.1 0.0 0.0 0.7 74.2 0.0 8.6 1.4 9.9 1.2 0.0 0.1 0.7 0.4 0.4 0.0 0.0 LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 3.6;Endothelial cells: 4.9;Erythroid cells: 1.7;Fibroblasts: 1.8;granulocytes: 3.8;Hepatic stellate cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HUVEC TERT2: 17.6;TIME: 9.6" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.7 0.8 0.5 1.4 0.4 3.6 4.7 0.5 1.2 3.9 0.6 1.4 0.8 1.9 1.0 1.7 3.3 3.6 1.8 0.4 0.4 1.9 1.4 1.9 1.9 0.7 0.8 2.9 0.9 1.2 1.4 4.6 0.6 2.0 1.4 1.0 1.2 0.5 0.7 2.7 1.4 3.4 0.6 4.1 1.1 1.7 0.5 1.0 4.0 0.6 0.7 1.7 2.8 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 17.6 0.3 0.2 0.7 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.5 0.4 0.5 1.2 0.4 0.4 0.7 0.8 0.6 0.6 0.5 0.8 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.1 4.9 0.0 1.7 0.0 0.0 0.0 1.8 0.0 0.1 3.8 0.1 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.4 0.3 0.0 0.3 0.0 0.0 0.0 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LSMEM1 "C7orf53, FLJ39575" ENSG00000181016 "Leucine rich single-pass membrane protein 1" Q8N8F7 7 112480853-112491062 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 81.6" "Cell type enhanced" "Detected in many" "Early spermatids: 49.2;Glandular and luminal cells: 27.7;Late spermatids: 67.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HeLa: 8.7" "Group enriched" "Detected in many" 4 "amygdala: 1.4;basal ganglia: 1.0;cerebellum: 4.0;olfactory bulb: 3.3" "Low region specificity" "Detected in many" "HPA013753, HPA047988" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol Vesicles "HPA013753: AB_1848926, HPA047988: AB_2680229" "unprognostic (6.87e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-2)" "unprognostic (2.77e-2)" "unprognostic (1.38e-1)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (6.68e-2)" "unprognostic (3.54e-2)" "unprognostic (2.80e-3)" "unprognostic (1.47e-6)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.25e-2)" "unprognostic (3.42e-2)" 2.2 2.1 1.2 0.2 1.7 0.3 1.5 2.1 2.5 1.7 1.1 2.0 0.5 1.0 1.0 2.0 1.6 0.1 2.9 1.2 1.7 4.0 7.2 4.3 0.1 1.2 1.1 1.7 5.5 0.0 2.3 0.2 1.1 2.5 0.3 0.8 1.7 0.3 81.6 1.4 2.2 0.1 0.8 4.2 2.7 2.9 1.3 0.1 2.2 17.0 0.0 1.8 2.2 1.5 0.0 0.1 0.1 0.6 0.5 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.2 8.7 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.9 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.7 1.3 0.0 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 2.1 2.5 1.2 1.7 1.2 1.1 1.1 0.8 1.3 1.5 16.8 0.0 2.8 5.9 5.1 5.5 2.7 1.3 9.6 2.1 12.8 23.4 9.9 2.8 2.2 1.8 2.1 1.3 9.5 17.5 0.0 0.8 49.2 12.7 18.4 5.3 3.0 0.0 8.5 0.9 1.1 7.2 7.7 27.7 0.0 0.5 1.1 1.0 4.0 0.0 7.6 5.7 0.0 1.2 4.8 67.8 0.9 13.6 1.8 3.7 1.8 0.6 0.0 1.5 5.0 0.8 7.1 0.4 4.2 6.1 5.2 0.5 1.4 3.2 0.0 22.3 8.1 0.5 0.5 9.5 4.7 1.9 6.3 2.2 5.4 3.6 LSMEM2 "C3orf45, FLJ38608" ENSG00000179564 "Leucine rich single-pass membrane protein 2" Q8N112 3 50279087-50288114 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.9;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 6 "Late spermatids: 283.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079523 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA079523: " "unprognostic (2.84e-3)" "unprognostic (6.54e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.46e-2)" "unprognostic (2.48e-1)" "unprognostic (6.49e-3)" "unprognostic (1.71e-1)" 0.4 0.4 2.9 0.1 4.8 0.4 0.3 3.1 3.7 1.3 1.8 0.5 0.3 0.7 0.2 0.5 0.7 0.2 23.9 3.2 3.2 0.8 0.2 0.4 0.0 3.7 3.7 1.2 0.2 0.0 0.1 0.1 3.4 0.4 0.1 0.3 0.2 0.4 16.5 0.2 0.3 0.4 2.7 0.2 0.3 3.9 3.8 0.0 0.2 5.5 0.0 0.4 0.8 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.8 3.1 3.7 3.2 3.2 3.7 3.7 3.4 2.7 3.8 6.0 1.0 0.0 0.6 0.7 0.3 1.0 0.2 0.2 0.0 0.2 1.5 0.9 4.4 0.0 0.8 1.8 0.0 0.1 0.3 0.9 0.0 0.1 40.5 3.3 0.6 0.8 0.0 0.0 0.2 0.2 0.1 0.4 0.0 10.1 5.1 0.2 0.0 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.4 283.1 1.2 0.3 1.8 0.0 0.0 0.5 0.0 0.0 2.8 0.2 0.0 0.7 0.0 0.4 1.5 0.1 0.2 0.2 0.0 1.4 4.7 1.8 1.1 0.4 1.3 0.1 0.2 0.1 0.7 0.1 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 78.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 27.8;monocytes: 96.5;Proximal enterocytes: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.8;HDLM-2: 21.7;Karpas-707: 85.3;RT4: 30.1;THP-1: 22.3" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" 2.0 1.9 1.1 18.7 1.0 9.6 9.4 1.1 1.2 7.3 0.7 12.4 18.0 2.6 0.7 5.0 8.5 7.7 1.0 0.9 1.3 3.7 2.0 7.7 30.3 1.7 1.1 1.0 1.4 1.1 0.6 1.3 1.6 1.8 11.9 0.7 7.8 2.6 0.3 7.4 17.6 2.3 1.8 18.4 7.1 0.4 1.2 78.4 17.3 0.9 22.1 10.3 2.2 1.8 3.5 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 9.1 21.8 15.7 0.7 0.0 0.0 0.4 0.0 0.1 0.0 21.7 0.0 4.4 0.2 0.1 0.4 3.3 0.1 0.3 0.1 0.6 0.2 0.0 11.1 0.0 0.0 85.3 0.0 0.0 0.0 5.8 0.5 0.5 0.0 6.0 0.0 3.8 6.4 30.1 0.0 0.0 7.0 5.0 0.0 0.2 0.0 22.3 16.7 0.0 0.0 0.0 0.0 13.2 2.4 3.0 0.0 7.7 0.0 2.6 1.2 2.4 4.2 1.7 4.6 3.7 3.8 4.8 2.9 2.7 4.3 5.1 3.7 5.2 0.7 1.0 3.0 1.4 1.1 1.0 1.1 1.2 0.9 1.3 1.7 1.1 1.6 1.8 1.2 1.8 1.7 0.0 3.4 0.0 15.4 7.5 2.2 5.6 7.4 0.2 9.9 12.1 0.5 4.3 6.3 23.9 2.1 0.1 10.6 27.8 0.0 0.8 0.6 15.4 1.3 3.3 1.8 6.9 0.0 5.5 0.1 1.8 8.6 9.4 11.4 1.7 2.2 0.2 3.9 0.0 0.0 9.8 4.1 10.1 11.3 0.3 2.5 11.5 5.4 0.0 96.5 0.2 13.4 0.0 0.0 4.9 10.9 0.4 8.1 1.3 33.5 2.0 20.7 0.2 0.0 3.7 1.3 0.0 0.7 4.5 6.7 0.3 14.2 0.9 12.3 5.6 LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.8;parathyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.6;Excitatory neurons: 26.2;Horizontal cells: 20.2;Melanocytes: 19.6;Rod photoreceptor cells: 18.5;Sertoli cells: 65.7;Smooth muscle cells: 15.4" "Cancer enhanced" "Detected in all" "melanoma: 59.2" "Group enriched" "Detected in many" 5 "amygdala: 13.1;basal ganglia: 11.6;cerebral cortex: 14.8;hippocampal formation: 14.5;white matter: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 19.7;SK-MEL-30: 75.0;U-698: 23.2;WM-115: 50.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 23.2;basal ganglia: 66.8;cerebral cortex: 45.5;hippocampal formation: 36.3;olfactory bulb: 26.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoli "HPA006294: AB_1079288, HPA022046: AB_1853455" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (6.27e-2)" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.41e-2)" "unprognostic (9.06e-3)" "unprognostic (6.81e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (9.28e-6)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (6.82e-3)" 3.7 1.7 13.1 1.5 11.6 0.1 3.0 0.0 14.8 2.0 0.0 1.3 0.5 2.9 0.9 5.3 1.6 3.5 5.0 14.5 0.6 4.7 0.7 7.0 1.1 0.0 0.1 1.2 1.5 54.2 2.2 6.5 0.3 2.8 0.4 3.5 1.4 1.1 1.9 4.6 0.9 2.5 0.0 0.5 1.4 7.5 2.3 1.9 2.7 2.0 0.5 2.3 1.7 9.2 0.1 0.0 9.7 8.3 0.0 0.0 1.2 5.0 0.1 4.3 3.7 0.3 0.1 11.1 3.5 3.1 1.6 0.2 0.5 0.2 2.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 1.7 0.9 0.1 1.8 0.0 0.6 0.0 11.7 0.0 0.1 14.4 0.0 19.7 0.1 12.2 0.0 0.0 0.0 15.6 0.0 2.7 0.4 14.8 12.9 0.0 0.0 75.0 8.2 0.1 0.4 0.0 5.1 3.5 0.1 1.5 0.1 0.1 23.2 0.1 1.1 50.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.1 11.6 0.0 14.8 14.5 0.6 0.0 0.1 0.3 0.0 2.3 9.2 3.9 0.0 0.0 1.6 0.0 1.3 0.8 1.0 17.6 1.8 0.3 11.3 4.6 0.0 0.1 0.0 4.2 7.1 0.4 0.0 1.9 0.0 0.5 0.6 1.3 3.2 0.0 0.0 26.2 0.0 2.3 2.4 0.0 0.5 0.0 3.5 0.0 0.0 0.9 20.2 2.9 0.0 2.0 0.0 0.0 0.8 1.2 0.2 19.6 1.9 0.0 0.9 0.0 6.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 18.5 65.7 1.1 15.4 0.2 1.1 7.3 0.1 0.8 1.4 2.5 0.0 0.0 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.2;Excitatory neurons: 12.2;Horizontal cells: 28.6;Inhibitory neurons: 12.2;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.8" "Low region specificity" "Detected in all" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA003047: AB_1079298" "unprognostic (9.30e-2)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "unprognostic (3.94e-2)" "unprognostic (5.61e-3)" "unprognostic (8.72e-3)" "unprognostic (2.41e-3)" "unprognostic (1.43e-1)" "prognostic favorable (3.95e-4)" "unprognostic (7.91e-2)" "prognostic favorable (6.86e-6)" "unprognostic (4.60e-3)" "unprognostic (2.71e-1)" "unprognostic (6.03e-3)" "unprognostic (5.99e-3)" 1.6 3.2 10.0 1.6 10.2 0.3 1.6 3.0 20.6 2.8 0.0 2.2 0.5 3.3 1.7 1.0 2.5 1.1 2.2 12.1 17.0 2.1 0.3 1.3 2.5 7.7 5.1 4.7 2.6 6.1 6.0 0.0 7.9 3.2 0.9 6.4 1.7 4.0 1.1 1.8 1.8 2.6 1.0 2.7 1.6 0.4 9.8 2.9 2.1 0.9 1.9 2.1 1.7 6.7 0.2 3.8 3.9 7.5 2.7 1.5 3.4 2.9 2.9 2.4 1.3 0.8 0.6 0.8 1.4 2.5 7.8 2.9 5.8 5.4 1.9 1.9 0.1 0.0 0.0 2.5 0.5 1.5 0.5 1.1 2.4 0.6 0.6 0.1 0.9 4.2 0.3 0.0 3.6 0.5 4.3 0.2 4.7 0.0 5.8 3.4 2.9 0.0 3.1 0.0 0.0 2.0 0.0 0.4 0.6 3.9 1.7 0.1 0.5 3.6 4.5 3.8 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.2 0.5 0.0 0.2 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 10.0 10.2 3.0 20.6 12.1 17.0 7.7 5.1 7.9 1.0 9.8 6.7 0.8 3.2 2.6 3.3 1.7 0.5 0.7 1.2 1.2 11.2 0.9 1.9 1.9 1.5 1.1 1.8 4.2 0.2 1.4 0.3 1.9 1.4 0.0 0.4 1.3 2.4 0.0 0.4 12.2 1.5 0.4 1.3 1.1 0.4 1.3 1.5 1.8 0.2 0.1 28.6 12.2 0.4 0.0 0.3 0.0 0.1 1.5 0.1 0.0 3.7 0.1 5.5 2.1 5.5 5.0 0.7 0.0 4.5 0.3 0.3 0.0 1.3 0.3 5.0 19.7 2.7 3.6 0.3 0.2 0.6 0.1 0.1 2.5 0.8 0.1 0.2 MAGEF1 ENSG00000177383 "MAGE family member F1" Q9HAY2 3 184710364-184712064 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046899, HPA054190" Uncertain Approved "Actin filaments" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Actin filaments" "HPA046899: AB_2679859, HPA054190: AB_2682411" "unprognostic (7.36e-3)" "unprognostic (3.79e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.46e-3)" "unprognostic (2.34e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (2.80e-3)" "unprognostic (1.82e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.59e-4)" "unprognostic (7.65e-2)" "unprognostic (8.97e-2)" "unprognostic (3.15e-3)" "unprognostic (1.19e-1)" 16.8 26.9 28.9 16.4 29.3 2.7 24.0 29.6 33.4 33.7 31.3 28.2 17.4 32.4 35.9 20.7 26.1 15.5 26.2 29.1 37.7 36.3 25.4 20.3 21.3 29.0 29.8 27.4 29.3 35.5 56.3 23.1 29.2 30.3 17.1 27.0 25.9 26.8 32.6 22.7 20.3 19.1 29.7 19.1 27.0 12.3 31.8 21.7 29.7 21.7 17.6 27.3 21.7 27.9 86.3 22.3 89.8 56.1 32.0 12.9 61.8 32.1 34.9 53.2 53.3 54.8 31.3 59.1 65.2 29.2 88.1 60.0 46.2 27.7 49.0 96.2 65.1 17.3 32.9 77.4 31.5 27.4 27.4 29.7 34.4 33.9 10.7 25.4 13.0 19.3 30.3 40.0 31.5 108.8 10.4 60.8 56.9 54.6 38.4 29.9 72.6 18.4 39.5 56.4 99.0 94.6 49.5 83.1 77.4 50.0 132.4 10.1 9.1 35.0 61.6 41.1 62.9 82.9 65.6 78.7 27.6 9.8 46.3 0.1 1.4 2.5 1.6 0.3 0.6 2.8 2.2 1.8 5.7 4.7 6.1 3.1 0.2 1.2 0.2 0.4 2.3 0.9 28.9 29.3 29.6 33.4 29.1 37.7 29.0 29.8 29.2 29.7 31.8 27.9 6.5 32.1 25.8 10.4 22.1 18.7 52.7 56.9 30.1 60.3 37.5 33.7 19.2 48.6 33.0 42.3 10.4 103.2 6.0 9.2 146.8 54.3 1.2 27.0 22.3 16.0 49.3 13.2 14.6 41.3 56.4 37.3 27.5 19.0 5.7 36.1 20.3 26.2 68.6 63.9 15.1 46.1 71.2 8.1 36.3 3.9 55.3 10.1 24.9 6.5 32.3 67.3 20.6 13.6 12.6 30.0 22.4 57.2 26.5 44.3 11.2 64.8 30.1 49.2 32.9 30.7 33.4 21.3 8.9 29.6 13.8 60.5 11.4 56.8 32.5 72.3 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Excitatory neurons: 72.8;Hepatic stellate cells: 63.9;Hepatocytes: 57.8;Inhibitory neurons: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.7" "Lineage enriched" "Detected in single" 5 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "AF22: 30.5;HSkMC: 108.9;U-266/70: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 12.5 11.6 13.3 9.4 15.2 2.2 6.2 16.6 16.1 19.6 27.3 10.0 4.5 14.5 7.5 7.0 9.7 18.6 10.1 15.9 16.9 25.4 29.6 9.2 12.4 45.1 23.2 17.3 3.6 24.0 17.1 21.1 26.1 17.6 4.6 11.0 5.7 17.9 4.6 8.1 6.1 19.9 29.4 19.3 7.3 4.2 16.4 10.5 26.0 5.5 9.4 12.3 9.1 37.8 0.1 0.4 30.5 6.4 22.4 17.2 8.6 0.4 5.8 1.4 0.4 0.6 0.2 0.1 0.3 2.3 3.9 0.4 3.0 0.3 0.6 9.8 1.3 0.6 0.5 0.1 2.6 5.2 12.0 108.9 0.5 0.7 0.0 0.4 0.1 1.2 0.1 1.3 0.0 1.6 0.0 5.8 7.8 0.1 0.2 0.6 18.9 0.6 0.2 0.7 17.7 0.6 0.7 4.7 1.5 5.5 2.4 3.6 0.1 0.0 1.6 20.1 0.7 31.7 0.1 0.1 4.6 10.7 1.5 0.3 0.9 0.4 0.3 0.6 0.5 0.2 2.1 0.9 0.3 0.5 4.7 2.7 0.6 0.4 0.8 0.2 0.5 0.7 13.3 15.2 16.6 16.1 15.9 16.9 45.1 23.2 26.1 29.4 16.4 37.8 5.8 3.2 3.2 18.3 2.0 6.6 2.9 3.6 5.2 23.5 1.1 1.5 7.0 4.3 7.3 22.0 54.2 10.6 1.6 0.5 9.8 1.0 0.3 0.4 8.1 8.4 3.0 2.7 72.8 3.8 0.9 23.3 1.1 0.6 2.5 0.3 63.9 57.8 24.8 21.9 65.8 0.1 16.2 19.0 4.3 2.1 27.1 6.8 1.8 39.4 3.3 17.8 3.1 25.1 21.7 1.4 0.3 22.2 2.2 2.0 0.0 23.3 2.2 4.4 6.6 17.0 7.1 0.2 2.9 1.0 5.3 42.7 6.9 0.7 0.2 1.9 MAP6D1 "FLJ12748, SL21" ENSG00000180834 "MAP6 domain containing 1" Q9H9H5 3 183815922-183825594 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.6;choroid plexus: 24.9;skeletal muscle: 26.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocytes: 101.3" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "T-47d: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037991 Enhanced Supported Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA037991: AB_10672503" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-3)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-1)" "unprognostic (1.28e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (8.81e-12)" "unprognostic (1.08e-1)" "unprognostic (2.96e-3)" "unprognostic (1.86e-1)" "unprognostic (5.72e-2)" 0.8 0.9 40.9 0.3 66.1 0.2 0.9 60.3 73.2 1.1 24.9 1.3 0.7 1.0 0.9 1.4 1.1 0.4 1.8 40.9 44.5 1.2 1.2 0.7 0.7 67.1 59.1 1.1 4.7 0.4 2.2 0.3 60.4 3.4 0.3 1.0 1.2 0.7 26.9 3.6 1.0 0.4 53.0 1.3 0.7 1.3 56.3 3.6 1.0 14.3 0.4 1.0 1.2 102.6 3.5 2.1 3.6 0.7 0.9 1.2 2.8 4.2 0.8 7.3 5.3 2.5 0.1 0.3 5.4 6.1 3.6 2.7 6.9 1.6 4.5 2.3 11.8 0.5 0.0 0.0 2.3 4.5 1.5 0.5 0.6 1.7 0.8 0.4 1.7 5.5 0.5 0.0 0.7 14.8 10.0 5.8 2.2 2.0 6.7 5.0 5.7 0.0 0.4 0.0 11.7 2.1 2.9 2.2 4.4 2.5 63.9 4.2 0.8 1.8 2.5 2.7 6.1 2.4 1.6 1.4 0.6 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 40.9 66.1 60.3 73.2 40.9 44.5 67.1 59.1 60.4 53.0 56.3 102.6 0.0 0.0 0.0 4.9 0.1 1.1 0.7 0.9 0.6 2.5 0.0 0.0 2.4 0.0 0.4 0.0 2.1 0.3 0.0 0.9 0.0 0.0 3.4 0.0 0.0 0.3 2.4 0.4 7.4 0.0 0.5 0.4 1.1 0.0 0.0 0.0 0.7 0.4 0.9 1.7 3.5 0.4 4.1 0.0 0.7 2.2 0.9 0.3 0.0 0.0 0.5 0.8 1.0 7.1 101.3 0.0 0.1 0.0 0.2 2.4 0.2 0.0 0.3 1.9 0.0 1.6 0.4 2.9 2.1 1.0 1.4 0.7 0.3 0.0 0.3 0.7 MBOAT1 "dJ434O11.1, LPEAT1, MGC44669, OACT1" ENSG00000172197 "Membrane bound O-acyltransferase domain containing 1" Q6ZNC8 6 20099684-20212469 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 18.8;Langerhans cells: 25.2;Oligodendrocytes: 41.5;Respiratory ciliated cells: 19.1;Suprabasal keratinocytes: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 42.2;HEL: 40.6;T-47d: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.26e-2)" "unprognostic (4.18e-2)" "unprognostic (2.06e-2)" "unprognostic (5.85e-3)" "unprognostic (3.88e-2)" "unprognostic (5.31e-2)" "unprognostic (2.55e-2)" "unprognostic (6.57e-3)" "unprognostic (1.87e-1)" "unprognostic (1.62e-3)" "prognostic unfavorable (9.15e-4)" "unprognostic (2.90e-2)" "unprognostic (5.59e-2)" "unprognostic (5.17e-2)" "unprognostic (2.56e-1)" "unprognostic (1.70e-1)" "unprognostic (4.24e-2)" 7.3 3.3 1.4 6.0 3.6 11.1 12.5 4.6 2.4 13.3 1.9 19.2 13.8 14.2 5.8 10.5 21.7 8.4 5.9 1.1 2.1 6.1 4.5 7.4 5.4 7.4 3.8 12.5 5.8 5.7 2.4 4.0 6.3 9.3 18.9 1.2 8.1 5.3 1.9 6.8 16.4 8.4 4.6 7.3 15.2 1.4 4.1 2.7 7.6 2.2 5.2 8.6 10.9 9.4 4.5 4.7 8.3 6.6 0.9 2.7 0.6 7.1 2.0 4.4 5.1 2.3 19.0 0.0 14.5 6.8 3.9 42.2 7.6 3.6 6.3 11.3 4.5 40.6 7.9 0.1 5.5 10.6 11.9 1.2 3.6 1.9 8.1 2.3 2.4 7.1 5.4 7.2 1.0 4.7 6.3 10.1 2.1 4.4 2.3 2.0 9.1 25.0 5.9 8.7 0.4 5.3 1.4 8.6 9.0 15.9 31.2 5.3 2.0 6.0 4.2 3.6 3.4 9.7 20.9 0.1 0.6 7.9 7.9 39.9 27.6 66.8 3.9 33.3 20.2 2.6 9.1 7.2 15.1 1.6 2.6 2.6 34.4 4.4 41.1 18.5 13.5 7.9 1.4 3.6 4.6 2.4 1.1 2.1 7.4 3.8 6.3 4.6 4.1 9.4 1.3 3.2 0.5 0.3 1.7 11.0 0.9 3.5 4.6 0.0 2.4 1.3 0.4 0.0 6.6 0.0 0.0 0.1 3.7 3.5 1.9 2.7 0.0 4.7 3.1 2.5 0.0 8.4 1.1 1.2 0.1 6.4 18.8 7.5 0.0 1.9 1.1 0.0 1.5 0.0 0.5 2.0 2.0 1.0 25.2 0.0 0.3 4.4 8.8 6.5 4.5 1.3 0.0 0.0 41.5 1.5 7.7 0.0 1.5 0.8 5.5 0.0 19.1 0.1 0.0 1.0 3.6 0.0 0.1 5.4 15.5 0.3 6.4 10.4 3.0 1.8 MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 11 "Oligodendrocytes: 2895.5" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 99.3;SK-MEL-30: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" 27.3 7.1 15448.6 20.9 21296.6 43.0 20.9 19749.8 26916.8 17.3 9144.9 19.0 18.6 13.2 7.9 20.5 31.5 17.2 24.1 12696.6 16271.8 28.7 23.5 20.0 26.9 30812.9 22193.8 22.3 22.8 47.5 26.7 4.7 25986.2 15.3 16.9 7.5 22.0 13.0 140.8 28.7 20.7 8.7 23219.4 28.0 17.5 6.1 19406.0 12.5 22.2 81.6 27.8 19.0 20.2 30044.2 26.1 22.4 0.2 0.8 35.8 53.1 8.5 0.6 0.6 0.8 0.6 3.2 39.2 15.9 4.4 1.7 0.2 49.9 3.8 22.1 0.7 60.7 5.3 10.4 3.9 5.2 22.5 99.3 65.3 7.7 18.4 19.8 30.3 16.4 6.5 37.9 0.0 3.6 0.0 3.2 4.1 50.6 2.2 15.6 18.1 1.5 0.4 35.9 34.5 34.3 1.8 0.3 3.2 0.0 204.7 6.1 0.6 60.5 0.1 0.2 0.5 0.2 2.8 0.1 0.5 16.9 5.8 62.0 2.5 21.7 8.5 32.4 21.6 8.1 13.1 5.9 15.4 28.1 9.2 5.1 9.1 17.0 39.5 28.0 8.1 11.9 14.9 11.6 15448.6 21296.6 19749.8 26916.8 12696.6 16271.8 30812.9 22193.8 25986.2 23219.4 19406.0 30044.2 5.5 48.1 39.5 10.7 86.8 118.8 61.1 28.1 84.2 52.8 24.2 22.7 45.0 35.8 50.3 103.0 2.1 0.7 221.8 48.7 41.1 43.7 5.9 159.8 11.2 9.4 49.8 68.8 32.4 35.8 0.8 36.2 59.1 161.1 71.5 2.1 10.0 30.2 44.4 1.7 47.1 51.4 44.7 78.3 123.1 6.3 28.3 98.2 92.5 45.0 84.4 25.7 247.2 124.7 2895.5 60.4 25.5 14.3 45.3 117.6 37.5 36.0 54.0 6.1 0.0 88.7 8.4 7.7 1.1 75.6 154.7 0.7 151.6 0.0 42.1 103.7 MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 43.5;epididymis: 13.9;parathyroid gland: 35.3" "Group enriched" "Detected in many" 7 "Enteroendocrine cells: 113.6;Melanocytes: 151.2" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.9;HAP1: 12.7;RH-30: 15.7;SK-MEL-30: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" 3.0 43.5 0.7 0.2 0.2 0.0 2.2 0.0 4.0 5.1 3.3 1.0 5.4 5.7 13.9 0.3 1.7 0.3 4.4 3.5 0.1 5.0 0.1 4.5 0.1 0.0 0.1 2.1 7.4 35.3 7.0 2.5 0.1 0.3 1.0 0.1 3.7 0.6 0.2 4.3 2.2 1.9 0.2 0.9 2.6 0.6 0.5 4.3 1.9 1.1 0.2 0.4 2.4 0.0 9.0 2.0 0.0 0.0 6.6 5.9 2.4 0.1 12.9 3.2 8.8 0.6 1.5 0.0 0.9 0.1 3.0 0.0 12.7 4.2 2.0 3.6 8.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 1.5 2.6 1.5 3.2 0.0 0.0 0.0 0.0 6.3 0.7 0.0 0.0 1.0 0.0 1.1 0.0 15.7 0.0 0.4 0.0 0.5 0.0 0.4 0.0 29.3 0.9 5.2 6.5 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 4.0 3.5 0.1 0.0 0.1 0.1 0.2 0.5 0.0 16.6 16.0 1.7 0.0 0.0 8.7 3.5 7.0 0.6 0.0 4.2 1.9 6.8 11.5 2.5 3.7 0.0 9.0 0.1 0.3 0.0 1.7 0.4 0.8 8.1 2.0 113.6 0.0 1.2 9.6 0.2 18.4 1.5 1.9 0.0 0.3 0.0 0.1 3.5 0.0 0.4 2.5 6.1 0.0 7.1 0.1 1.8 3.2 151.2 2.8 1.6 0.0 0.0 0.0 0.1 3.6 12.9 0.0 0.3 1.4 4.1 3.4 0.7 0.0 6.6 6.3 1.2 1.8 4.1 0.4 3.4 2.6 1.4 1.0 3.8 0.6 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.9;placenta: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 84.7;Endothelial cells: 37.2;Leydig cells: 40.4;Peritubular cells: 25.2;Sertoli cells: 26.3;Smooth muscle cells: 27.0" "Cancer enriched" "Detected in many" 8 "glioma: 15.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AN3-CA: 248.8;U-138 MG: 62.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 3.5;spinal cord: 9.5" HPA053793 Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA053793: AB_2682264" "unprognostic (1.10e-1)" "unprognostic (4.72e-2)" "unprognostic (9.82e-3)" "unprognostic (4.22e-2)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-3)" "unprognostic (4.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-5)" "unprognostic (3.67e-3)" "unprognostic (1.13e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-4)" 37.9 1.1 0.6 2.9 0.3 0.0 26.2 0.3 0.7 4.3 0.2 5.7 0.4 2.9 2.4 2.4 5.0 6.1 11.8 0.3 0.7 0.5 0.7 12.9 9.1 2.2 0.9 2.4 1.6 1.2 1.2 42.1 1.0 1.9 1.9 0.2 4.4 1.5 9.9 6.9 2.2 4.5 0.7 0.9 2.3 2.3 1.0 3.3 8.6 13.3 5.3 6.1 4.8 0.5 0.0 0.0 0.0 248.8 2.4 8.5 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 62.9 0.0 25.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.7 0.3 0.7 2.2 0.9 1.0 0.7 1.0 0.5 84.7 0.0 0.5 0.7 0.3 8.2 0.0 0.0 0.6 0.0 0.5 1.3 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 37.2 0.0 0.0 3.8 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 3.7 0.0 0.0 0.0 9.6 0.2 40.4 0.3 3.6 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 25.2 0.0 0.1 0.0 0.0 0.0 0.0 26.3 1.5 27.0 0.1 0.1 0.1 7.0 0.1 0.8 0.7 0.0 0.0 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 82.3;Excitatory neurons: 76.7;Suprabasal keratinocytes: 61.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.3;CACO-2: 45.2;CAPAN-2: 27.9;T-47d: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" 3.8 2.7 0.1 5.7 1.0 8.8 9.7 4.7 2.2 6.4 0.1 10.7 6.0 5.1 1.9 37.1 11.8 6.4 6.6 0.4 0.0 12.2 1.9 10.1 2.6 0.0 0.0 3.4 12.1 11.8 2.2 11.7 0.1 8.0 9.3 9.7 7.6 4.8 13.8 24.8 7.2 8.7 0.0 2.4 8.8 9.0 0.0 3.2 14.4 14.3 6.9 9.7 9.6 1.1 5.9 0.1 0.6 0.0 0.1 0.1 23.3 1.2 0.9 4.7 7.4 45.2 27.9 0.0 0.3 3.4 3.4 10.4 3.9 7.5 10.9 0.0 7.5 0.0 1.3 2.8 0.0 0.0 0.0 0.3 11.6 0.7 0.4 0.0 0.0 2.2 1.1 0.0 6.2 10.9 2.3 0.0 1.4 8.9 2.1 1.2 13.3 0.0 0.4 19.0 1.1 0.0 2.3 11.3 0.0 3.6 89.3 1.1 0.0 1.8 12.5 0.0 1.0 0.2 0.0 0.1 0.1 10.7 0.0 0.0 7.7 9.0 3.8 2.5 5.6 0.6 4.2 2.6 7.8 0.5 7.9 5.7 3.1 5.0 1.5 0.1 1.1 5.1 0.1 1.0 4.7 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.1 1.6 44.8 48.3 10.4 5.5 23.1 10.9 9.5 7.4 1.1 14.7 8.6 12.1 10.0 24.3 14.7 16.7 50.0 9.8 15.3 9.8 5.5 82.3 9.3 0.6 11.7 6.7 4.2 76.7 12.9 3.5 2.6 11.2 6.6 1.3 0.7 2.9 3.2 5.4 3.3 30.3 10.4 8.2 4.7 5.3 20.3 0.9 8.1 7.2 12.2 16.2 24.0 4.1 4.5 2.5 6.6 7.8 0.4 5.1 7.5 12.1 9.5 19.3 8.5 0.0 1.5 7.6 5.4 9.5 48.0 61.1 46.5 16.3 0.1 11.3 17.4 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Glandular and luminal cells: 34.1;Rod photoreceptor cells: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA068583: AB_2686009" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.13e-2)" "unprognostic (3.70e-1)" "unprognostic (7.37e-2)" "unprognostic (2.39e-1)" "unprognostic (5.85e-3)" "unprognostic (8.11e-3)" "unprognostic (8.93e-2)" "unprognostic (6.38e-3)" "unprognostic (6.62e-3)" "unprognostic (6.92e-2)" "prognostic favorable (4.20e-4)" "unprognostic (9.99e-2)" 5.9 8.2 3.9 5.4 8.9 5.9 21.4 17.9 5.6 6.7 6.2 5.6 6.4 3.4 5.0 29.8 5.8 2.8 0.7 4.6 4.5 5.4 17.8 10.3 10.8 5.6 4.7 2.5 2.2 7.3 7.6 7.7 5.9 2.4 5.8 46.9 4.9 6.1 2.7 20.2 5.5 1.8 3.3 4.4 6.8 1.1 6.5 9.9 6.6 0.9 15.1 5.5 14.3 5.0 20.9 5.1 5.9 3.5 3.9 2.1 13.1 7.0 5.6 4.6 8.9 24.3 15.5 6.7 6.0 4.3 11.5 13.0 17.9 26.5 10.1 14.1 15.1 10.6 5.6 43.5 2.3 6.0 3.9 3.9 11.2 5.3 7.4 4.6 4.0 15.2 5.3 17.8 2.9 82.8 17.0 5.7 23.3 12.4 4.8 9.8 13.9 10.7 12.3 29.3 16.4 8.6 4.4 36.4 40.3 13.7 20.2 2.8 0.5 9.8 2.5 5.0 10.7 23.0 15.3 17.5 6.0 22.2 7.5 1.6 0.1 0.2 0.7 0.1 1.2 1.1 0.6 1.1 0.1 0.6 0.3 0.5 0.8 0.8 0.2 2.1 1.0 0.1 3.9 8.9 17.9 5.6 4.6 4.5 5.6 4.7 5.9 3.3 6.5 5.0 0.6 3.2 13.4 7.8 4.3 2.7 12.1 0.6 9.6 14.4 24.1 12.1 0.8 2.8 9.2 7.3 60.5 21.7 8.5 3.8 3.9 3.2 0.3 14.0 1.9 1.1 1.8 2.1 21.1 2.5 4.7 1.8 5.6 34.1 1.3 0.6 1.4 8.3 13.4 1.7 21.4 1.8 2.0 0.8 3.0 0.0 2.5 4.0 5.4 6.5 21.3 7.6 2.1 8.5 12.8 7.5 4.6 7.5 7.0 7.0 3.1 1.1 3.0 40.1 6.6 1.2 1.2 1.1 4.6 28.7 1.6 25.9 4.0 1.0 2.9 22.6 MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 43.9;Cardiomyocytes: 26.9;Cytotrophoblasts: 9.9;Endothelial cells: 9.6;Extravillous trophoblasts: 10.0;Smooth muscle cells: 14.9;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 170 "amygdala: 9.4;basal ganglia: 15.1;cerebral cortex: 21.4;hippocampal formation: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA011286: AB_1853973" "unprognostic (2.00e-1)" "unprognostic (5.28e-1)" "unprognostic (1.30e-2)" "unprognostic (3.62e-1)" "unprognostic (7.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-1)" "prognostic favorable (6.20e-4)" "unprognostic (5.22e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (5.96e-2)" 21.4 7.3 9.4 8.6 15.1 3.8 18.3 0.0 21.4 19.0 0.0 9.9 9.7 14.9 9.1 14.5 14.0 13.3 11.8 21.7 0.0 8.4 5.9 13.2 7.6 0.0 0.0 7.1 12.1 22.2 4.9 21.7 0.0 15.5 10.8 8.6 11.6 15.2 11.9 16.6 7.9 15.6 0.0 5.1 10.1 17.5 0.0 10.3 16.9 14.5 8.1 11.3 12.2 0.0 17.6 17.8 17.8 13.2 5.9 11.0 8.0 4.9 13.3 7.4 10.6 7.7 16.4 9.4 12.4 8.4 9.3 13.8 12.9 14.4 13.5 23.1 7.0 6.0 13.6 13.3 8.2 4.2 5.4 8.4 14.6 12.8 8.3 7.8 14.7 12.2 7.9 9.7 5.6 15.1 13.4 2.8 6.0 4.7 4.8 20.5 13.7 8.1 7.3 17.3 6.2 10.8 23.9 10.2 4.9 8.2 18.0 3.5 9.4 15.3 14.9 4.4 6.4 6.6 8.8 8.4 16.6 7.1 11.7 0.2 0.5 0.0 1.1 0.7 1.7 3.7 1.9 0.9 0.7 1.5 2.4 1.3 0.3 1.1 0.8 1.7 0.9 0.6 9.4 15.1 0.0 21.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 9.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 10.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 10.4 0.4 0.0 0.0 0.0 MS4A8 "CD20L5, MS4A4, MS4A8B" ENSG00000166959 "Membrane spanning 4-domains A8" Q9BY19 11 60699585-60715807 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 129.7;intestine: 197.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 376.4;Enteroendocrine cells: 473.4;Ionocytes: 140.4;Proximal enterocytes: 694.6;Respiratory ciliated cells: 502.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.9;RPMI-8226: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007319 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA007319: AB_1854138" "unprognostic (7.28e-3)" "unprognostic (2.11e-1)" "unprognostic (9.03e-2)" "unprognostic (1.91e-2)" "unprognostic (2.52e-2)" "unprognostic (9.41e-2)" "unprognostic (4.89e-3)" "unprognostic (9.33e-2)" "unprognostic (7.97e-3)" "unprognostic (2.40e-1)" "unprognostic (2.40e-9)" "unprognostic (2.46e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-3)" 0.0 0.8 1.6 3.5 1.3 0.0 0.0 0.0 1.1 25.6 5.4 18.2 189.8 8.2 0.0 0.3 129.7 10.8 0.0 0.6 0.4 0.1 0.0 16.6 0.2 0.0 0.2 0.3 2.2 0.7 7.5 0.1 0.0 1.7 16.9 0.0 0.6 7.1 4.6 0.0 197.7 1.0 0.0 0.0 45.7 0.5 0.9 0.1 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 0.0 1.1 0.6 0.4 0.0 0.2 0.0 0.0 0.9 0.0 0.0 6.4 6.4 0.0 0.2 0.0 0.2 11.9 0.0 0.0 0.0 0.0 0.3 18.6 58.8 1.8 0.0 0.0 0.0 15.0 0.0 0.3 1.3 376.4 3.2 0.3 473.4 0.0 0.4 2.5 0.0 2.0 14.3 11.6 1.3 0.0 0.0 0.0 0.0 0.0 0.1 42.5 140.4 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 46.1 0.0 0.0 1.7 694.6 0.2 502.8 0.0 0.0 0.0 3.5 0.3 0.7 0.0 0.0 0.0 0.5 0.2 24.7 0.4 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSS51 "FLJ39565, ZMYND17" ENSG00000166343 "MSS51 mitochondrial translational activator" Q4VC12 10 73423579-73433561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 261.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.3;Excitatory neurons: 11.9;Inhibitory neurons: 9.7;Oligodendrocyte precursor cells: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038564 Uncertain Vesicles,Cytosol NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Vesicles Cytosol "HPA038564: AB_10674687" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.40e-3)" "unprognostic (2.06e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-3)" "unprognostic (3.05e-3)" "unprognostic (7.88e-3)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (1.50e-4)" "unprognostic (1.22e-1)" "unprognostic (1.78e-7)" "unprognostic (1.51e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-2)" 1.9 1.5 1.5 1.5 1.8 1.6 1.7 4.3 2.0 3.2 1.6 2.3 1.2 2.1 1.7 1.4 2.2 1.2 10.9 1.5 0.6 1.7 1.6 2.2 1.8 0.2 0.3 3.0 1.9 56.2 2.3 0.6 0.2 2.5 1.3 2.5 1.7 0.8 261.3 3.7 2.7 1.1 0.0 3.9 1.8 1.4 0.7 1.5 1.5 5.9 1.5 2.2 2.2 1.3 0.9 0.6 1.5 2.7 2.1 2.8 1.2 0.7 0.5 0.3 0.6 0.3 0.7 2.1 0.2 0.7 0.1 1.1 1.0 0.2 0.8 1.1 0.9 1.7 1.3 0.5 0.7 1.1 1.7 2.4 0.7 0.6 1.7 2.1 0.2 0.8 0.6 1.0 1.2 0.2 0.9 1.6 0.4 0.5 0.7 0.5 4.1 0.1 0.8 0.9 0.3 0.8 0.5 1.0 0.9 1.4 0.9 0.9 1.3 1.2 0.7 0.4 1.7 0.6 2.1 1.1 0.5 1.9 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.8 4.3 2.0 1.5 0.6 0.2 0.3 0.2 0.0 0.7 1.3 0.9 0.0 3.6 4.6 1.0 0.5 0.1 0.6 0.0 1.4 0.4 0.5 5.3 0.0 0.2 0.0 0.0 0.3 0.4 0.4 0.0 0.4 0.3 0.4 0.7 1.2 0.0 1.3 11.9 0.4 0.2 0.8 1.1 0.8 5.1 1.8 1.4 0.2 0.2 0.0 9.7 0.4 0.0 0.8 0.6 0.3 3.1 0.5 0.0 4.7 1.1 0.5 1.0 6.0 3.4 0.2 3.9 1.5 0.4 0.5 0.6 0.2 0.3 1.2 0.0 4.0 0.6 0.7 0.3 0.0 0.0 0.1 1.1 1.4 0.6 0.2 MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 362.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 84.6;NB-4: 17.3;U-266/70: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 29.3 28.0 8.1 1.0 8.3 6.3 8.2 8.8 14.0 12.6 8.1 5.1 50.6 8.9 11.3 7.3 10.5 7.4 4.9 8.1 8.4 96.9 927.9 5.9 3.6 8.4 8.4 12.5 16.4 9.4 29.3 5.8 8.3 12.9 2.1 5.3 8.1 5.1 3.6 14.8 31.1 2.1 8.1 13.9 8.8 34.9 8.2 2.2 36.4 2.9 1.7 6.0 6.9 8.3 0.2 0.4 1.2 2.0 3.7 7.6 3.7 1.1 1.4 0.6 0.8 3.9 1.2 0.3 2.6 1.3 0.5 0.8 0.6 1.5 0.6 1.3 0.7 0.6 2.6 84.6 5.8 0.0 1.6 10.2 2.6 0.7 2.1 14.1 1.4 3.5 0.7 9.9 1.9 0.6 0.5 17.3 0.2 1.1 1.0 0.4 0.5 2.2 4.2 0.6 0.2 2.8 0.0 1.6 0.4 2.5 1.5 5.7 0.9 1.9 0.6 0.1 0.2 21.8 2.9 0.5 2.2 3.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 8.3 8.8 14.0 8.1 8.4 8.4 8.4 8.3 8.1 8.2 8.3 3.1 6.4 3.9 10.1 3.5 2.9 4.6 5.8 6.8 8.2 6.1 10.2 2.2 45.8 5.4 27.6 8.4 4.8 1.0 5.1 62.6 6.9 7.6 2.3 3.5 3.4 8.3 29.7 1.1 3.9 19.7 5.2 9.2 3.2 1.3 36.9 10.0 362.8 1.4 1.7 2.0 8.9 6.1 10.7 1.4 2.6 3.1 1.2 3.6 2.8 0.1 8.9 0.0 3.0 2.9 2.1 7.2 1.9 1.6 1.3 57.0 61.9 6.7 6.9 0.0 2.3 10.9 21.8 9.2 2.6 4.7 5.1 2.1 22.8 13.7 3.4 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Extravillous trophoblasts: 166.5;Granulosa cells: 86.9;Microglial cells: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" 12.5 12.2 7.1 11.4 6.7 13.2 7.9 25.1 7.4 7.1 8.3 7.4 3.2 8.4 6.2 6.7 7.1 5.9 11.5 6.4 9.8 12.7 5.6 19.5 11.1 11.5 10.1 14.6 10.7 6.8 9.2 14.3 11.0 5.5 7.9 7.5 3.2 7.0 1.3 6.0 5.2 10.0 11.6 9.2 6.0 9.9 8.4 8.6 10.9 0.5 10.8 12.8 4.2 15.4 40.6 35.1 44.9 110.0 11.5 40.0 108.4 63.0 68.3 62.1 75.7 71.8 37.4 152.3 41.1 96.9 36.8 42.7 72.4 61.8 76.8 63.4 65.3 62.7 60.4 66.1 72.4 115.7 9.8 47.7 76.9 60.6 109.8 55.5 105.5 81.6 150.9 76.2 65.0 86.1 57.1 23.9 45.5 40.7 32.1 67.2 33.2 67.1 42.1 19.6 44.1 32.5 83.9 36.7 53.0 40.6 11.5 79.5 80.6 41.4 90.6 91.9 90.5 62.3 63.5 154.0 68.8 105.7 54.0 0.0 0.2 0.0 0.2 0.3 0.4 0.2 0.6 0.7 1.1 0.3 0.5 0.6 0.0 0.3 0.3 0.5 1.8 0.2 7.1 6.7 25.1 7.4 6.4 9.8 11.5 10.1 11.0 11.6 8.4 15.4 6.9 0.0 1.7 47.7 6.9 6.5 8.0 15.7 1.8 0.0 3.3 4.1 2.4 1.5 9.8 14.7 0.0 25.8 1.4 2.6 7.9 9.0 44.9 11.3 18.4 10.7 1.2 5.0 84.0 18.1 166.5 14.4 8.2 22.2 0.0 86.9 6.1 1.7 24.9 0.0 73.8 3.0 46.8 3.0 13.3 6.2 0.6 13.8 35.6 126.5 2.4 0.0 2.1 60.8 59.3 19.2 1.4 7.9 14.0 31.3 0.9 15.2 5.3 0.0 0.0 8.7 13.1 0.5 6.8 2.3 3.4 73.6 4.0 42.9 4.0 35.1 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYF5 bHLHc2 ENSG00000111049 "Myogenic factor 5" P13349 12 80716912-80719671 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 5.6;tongue: 8.9" "Cell type enriched" "Detected in single" 1159 "Skeletal myocytes: 347.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "LHCN-M2: 478.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA041691 Supported Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041691: AB_10796780" "unprognostic (2.65e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 478.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 347.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYH3 "HEMHC, MYHC-EMB, MYHSE1, SMHCE" ENSG00000109063 "Myosin heavy chain 3" P11055 17 10628526-10657309 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 29.0;seminal vesicle: 18.3;skeletal muscle: 20.6" "Cell type enriched" "Detected in many" 7 "Early spermatids: 411.9" "Group enriched" "Detected in many" 4 "head and neck cancer: 3.3;prostate cancer: 4.6;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 26 "HSkMC: 59.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA021808 Enhanced NA NA 29000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA021808: AB_1854242" "unprognostic (1.70e-2)" "unprognostic (1.10e-3)" "unprognostic (4.19e-4)" "unprognostic (3.35e-1)" "unprognostic (7.66e-2)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (1.67e-2)" "unprognostic (3.54e-1)" "unprognostic (7.84e-4)" "unprognostic (1.29e-1)" "unprognostic (3.24e-4)" "unprognostic (1.91e-2)" "unprognostic (6.17e-3)" "unprognostic (3.40e-2)" "unprognostic (3.49e-1)" 1.6 0.9 1.8 1.1 1.7 0.8 1.5 1.5 1.9 2.9 1.5 7.9 1.1 3.4 1.2 9.1 2.6 0.5 1.0 1.6 1.6 2.1 3.3 1.2 1.3 1.8 1.8 2.3 2.4 0.3 1.5 0.4 1.7 29.0 1.0 1.8 1.5 18.3 20.6 2.8 2.5 1.7 1.4 2.6 1.7 4.6 1.8 3.0 3.4 6.0 0.6 4.4 3.8 1.8 0.2 1.1 0.8 1.1 1.0 0.3 1.0 0.8 0.4 0.5 0.5 1.0 0.1 0.7 0.3 0.4 0.2 1.1 0.5 0.2 1.0 0.7 0.9 1.0 0.3 1.6 0.3 0.6 1.4 59.6 0.4 0.6 0.8 0.1 0.1 1.3 0.4 0.1 0.2 0.7 1.0 2.3 0.9 0.3 0.6 0.8 0.8 0.3 0.3 0.3 0.0 0.4 0.4 0.0 0.3 0.7 0.3 0.3 0.3 0.1 1.0 0.3 0.1 1.3 1.1 0.3 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.5 1.9 1.6 1.6 1.8 1.8 1.7 1.4 1.8 1.8 0.5 0.0 9.8 4.6 0.7 2.9 0.9 0.1 0.6 4.9 0.7 1.8 3.6 1.5 0.7 0.0 6.2 0.4 0.8 0.9 0.0 0.6 411.9 0.5 0.8 1.4 0.0 2.7 3.9 0.6 0.8 1.1 1.1 0.5 7.6 0.8 0.4 0.6 0.1 0.0 3.4 0.5 0.0 0.8 0.3 56.0 2.8 1.2 1.8 1.9 0.2 1.8 0.0 7.5 5.4 0.7 0.2 2.6 0.0 1.5 1.8 0.3 0.3 4.6 0.0 5.5 0.8 10.7 4.2 0.3 1.6 0.5 1.4 0.2 0.8 0.3 MYL1 ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 88 "skeletal muscle: 21805.2;tongue: 15591.3" "Cell type enriched" "Detected in some" 246 "Skeletal myocytes: 492.9" "Group enriched" "Detected in some" 18 "head and neck cancer: 36.0;prostate cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HSkMC: 51.4" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced "Intracellular and membrane" NA NA 21000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA046859: AB_2679842, HPA063034: AB_2684927, HPA073827: " "prognostic unfavorable (6.59e-4)" "unprognostic (1.88e-1)" 2.3 0.5 0.1 0.0 0.1 0.0 3.3 0.0 0.1 0.1 0.0 1.1 0.0 0.5 0.0 212.7 0.0 0.0 2.0 0.1 0.0 0.7 1.0 0.9 0.0 0.0 0.0 0.6 1.1 0.0 0.4 0.0 0.0 164.2 0.0 0.0 170.2 0.0 21805.2 4.0 0.7 0.0 0.0 0.4 0.7 0.5 0.0 7.4 2.3 15591.3 0.9 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 492.9 2.0 0.1 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 4234.5;skeletal muscle: 3072.7;tongue: 2082.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6094.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB004503: AB_2282358, HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.14e-3)" "unprognostic (5.30e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (3.03e-2)" "unprognostic (7.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.57e-3)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-1)" "unprognostic (9.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (4.58e-3)" "unprognostic (7.13e-2)" 492.0 246.2 83.6 358.2 86.6 455.0 423.8 91.2 123.7 311.2 114.1 448.8 315.2 258.1 267.0 410.9 274.7 354.6 4234.5 81.0 97.2 427.9 462.3 564.8 562.8 101.2 89.5 191.4 228.8 364.4 106.9 445.4 101.7 247.4 486.6 50.7 282.4 245.6 3072.7 280.7 332.6 317.3 97.0 566.3 369.0 106.8 93.5 461.6 314.3 2082.4 601.6 408.3 240.5 96.8 467.6 298.1 580.7 257.3 701.6 691.8 386.7 1045.3 1176.5 827.9 895.4 440.7 543.5 224.6 263.9 1412.9 627.3 192.7 360.9 601.0 736.0 326.9 129.4 236.6 297.2 360.0 1118.3 658.7 401.0 1129.5 803.3 698.0 420.0 799.7 1332.7 272.6 292.6 694.7 1748.4 793.6 282.9 571.7 253.3 496.5 199.3 167.0 341.1 384.7 1827.8 680.1 86.7 211.5 840.9 333.1 674.0 541.8 233.8 918.2 1717.0 212.6 508.4 635.5 828.0 166.9 278.8 351.6 665.5 249.5 798.1 3164.3 1120.8 2382.2 2287.2 1192.8 2280.2 1588.6 2106.9 2315.1 1639.0 1353.6 1901.6 2215.8 1785.1 1629.3 1464.6 2487.8 2068.3 4517.7 83.6 86.6 91.2 123.7 81.0 97.2 101.2 89.5 101.7 97.0 93.5 96.8 1206.6 737.2 291.0 4.6 530.9 635.9 973.5 1804.3 259.6 29.4 294.8 396.4 6094.3 449.0 949.8 511.3 12.5 748.1 1090.0 1033.5 471.6 1335.5 32.4 570.0 312.1 938.8 105.4 244.9 1.7 1487.7 1168.6 453.0 318.5 662.3 521.0 301.7 870.6 272.5 844.2 57.2 2.9 570.4 889.0 605.3 992.8 32.8 334.6 924.2 442.9 26.2 1616.2 92.6 1388.3 4.0 9.0 2236.5 977.2 396.5 207.4 817.8 758.0 757.7 673.1 42.4 571.9 378.7 757.0 78.9 166.5 262.6 545.1 666.0 1078.8 303.7 429.6 698.2 MYL5 ENSG00000215375 "Myosin light chain 5" Q02045 4 673580-682033 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 66.1" "Cell type enhanced" "Detected in many" "Late spermatids: 87.3;Proximal enterocytes: 55.5;Rod photoreceptor cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 60.4" "Not detected" "Not detected" "HPA037381, HPA039262" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA037381: AB_10672484, HPA039262: AB_2676418" "unprognostic (6.30e-3)" "unprognostic (1.42e-2)" "unprognostic (5.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.53e-2)" "unprognostic (1.33e-1)" "unprognostic (4.77e-3)" "unprognostic (2.38e-1)" "unprognostic (8.39e-2)" "unprognostic (1.61e-3)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (2.95e-2)" "unprognostic (3.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.91e-2)" 17.9 21.4 21.8 7.0 21.8 11.4 16.6 21.9 36.0 10.6 19.4 20.7 20.7 7.4 17.8 20.0 7.9 8.3 10.4 21.0 20.4 19.4 22.2 11.0 11.0 22.8 21.1 7.7 9.9 15.3 13.7 5.1 22.3 18.2 13.0 66.1 13.3 8.9 24.6 18.6 25.2 5.6 20.9 16.1 12.3 22.2 21.9 10.0 13.6 8.3 10.3 11.2 13.3 23.5 4.3 6.9 24.8 13.2 60.4 41.2 11.9 10.2 13.6 10.2 9.3 8.4 17.7 4.9 4.8 16.6 7.3 6.2 4.0 7.0 3.0 9.2 5.0 7.4 11.7 7.9 21.0 11.3 6.5 31.3 6.5 8.1 8.4 14.8 6.3 10.4 7.7 6.5 12.7 8.0 6.1 7.8 5.2 8.8 10.4 5.4 5.3 3.0 16.9 19.9 11.3 6.4 3.4 8.5 7.2 8.0 13.7 10.2 10.4 8.7 1.6 7.5 6.0 24.7 5.3 2.9 9.5 10.1 4.6 15.5 8.2 1.5 3.3 5.5 4.2 8.7 5.6 2.0 7.7 12.7 6.7 6.8 5.8 18.4 12.3 14.5 2.6 5.8 21.8 21.8 21.9 36.0 21.0 20.4 22.8 21.1 22.3 20.9 21.9 23.5 4.5 0.0 11.9 2.3 11.7 12.0 6.8 12.8 18.2 6.3 12.9 14.5 1.4 7.2 5.7 7.3 20.9 7.3 9.2 22.7 11.7 9.6 22.2 9.1 6.9 5.9 5.4 4.2 1.4 4.7 5.4 7.5 13.7 5.3 13.9 4.9 10.4 18.3 22.7 11.8 1.3 11.4 6.1 21.2 8.6 87.3 7.2 12.4 7.2 1.0 22.8 22.2 13.4 0.5 1.6 6.1 13.2 3.8 5.1 8.3 55.5 42.6 8.2 74.3 6.6 21.7 5.6 14.1 4.4 21.2 13.4 5.5 5.9 14.7 15.4 9.7 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 103.4;skeletal muscle: 46.5;tongue: 72.6" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 169.0;Endometrial ciliated cells: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HEL: 40.2;K-562: 6.5;SK-BR-3: 7.9" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.5" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 1.9 0.1 1.7 0.3 0.1 1.1 2.3 0.4 1.7 0.0 0.1 0.3 0.8 4.3 1.7 0.2 103.4 2.5 2.8 1.1 0.1 0.4 0.2 9.8 12.2 0.3 0.1 0.0 0.4 0.5 8.2 2.2 0.1 0.2 2.1 0.1 46.5 0.1 0.1 0.2 5.9 0.1 0.1 6.0 1.9 0.1 0.1 72.6 0.1 0.0 0.0 3.0 0.0 0.1 0.1 0.1 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 2.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.5 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 7.9 0.2 3.5 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.9 1.7 1.1 2.3 2.5 2.8 9.8 12.2 8.2 5.9 1.9 3.0 0.2 0.0 3.3 0.7 0.5 0.0 0.7 0.0 0.0 0.9 1.3 0.0 169.0 0.0 3.7 0.0 2.1 2.0 0.2 0.0 0.0 0.0 8.1 44.8 7.1 1.7 0.0 0.0 0.9 0.2 0.5 6.7 0.0 2.2 1.3 1.6 0.7 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 7.2 0.6 0.8 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.8 0.0 0.2 8.7 1.3 0.0 4.9 2.7 1.0 0.7 0.0 0.0 0.3 0.8 0.7 0.0 0.8 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 MYO5C MGC74969 ENSG00000128833 "Myosin VC" Q9NQX4 15 52192322-52295804 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 68.5;Alveolar cells type 1: 131.4;Alveolar cells type 2: 84.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 25.4;MCF7: 46.3;OE19: 41.2;RT4: 26.4;SK-BR-3: 34.0;T-47d: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020790, HPA032115, HPA032116" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" Cytosol Nucleoplasm "CAB020790: , HPA032115: AB_2674158, HPA032116: AB_2674159" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "prognostic favorable (5.18e-5)" "unprognostic (2.94e-1)" "unprognostic (4.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.53e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-3)" "unprognostic (4.82e-2)" "prognostic favorable (2.47e-5)" "prognostic favorable (5.82e-4)" "unprognostic (9.15e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" 11.1 1.5 3.0 2.8 3.3 0.8 13.2 7.9 3.1 14.1 17.0 14.0 5.3 4.2 12.8 7.0 11.5 6.9 1.6 2.6 2.9 5.6 3.4 13.8 1.9 5.1 2.8 1.6 27.3 13.7 7.3 2.5 6.3 10.3 17.7 1.6 21.1 4.4 2.1 4.8 5.1 4.0 7.3 3.5 19.4 4.7 3.3 1.9 17.9 2.6 2.4 4.4 4.4 5.9 21.4 25.4 3.5 0.0 0.0 0.1 3.0 0.0 0.3 0.1 0.0 3.9 8.8 1.2 5.3 0.1 0.2 3.4 5.3 7.4 0.0 1.1 8.4 0.1 17.3 15.7 0.0 0.0 0.2 0.0 7.2 0.0 6.8 3.6 5.6 0.9 0.0 0.3 0.1 46.3 1.3 0.2 1.4 41.2 12.0 17.6 2.1 10.6 19.5 26.4 3.5 3.9 1.6 34.0 0.0 5.4 40.9 0.0 0.0 0.0 0.2 0.0 3.3 0.7 0.7 2.1 0.1 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.0 3.0 3.3 7.9 3.1 2.6 2.9 5.1 2.8 6.3 7.3 3.3 5.9 68.5 131.4 84.5 3.9 1.5 0.6 20.5 10.2 2.2 0.4 22.4 10.9 4.9 18.6 47.1 22.0 0.0 2.3 0.3 26.5 3.9 21.1 2.8 34.1 4.8 26.1 5.4 2.1 29.3 29.6 1.5 3.7 41.3 50.4 3.8 5.1 2.5 5.1 0.9 0.0 3.9 47.1 22.4 0.8 3.1 3.2 1.8 1.4 7.2 14.0 0.1 5.6 1.0 8.0 2.8 39.0 21.5 0.4 2.7 28.1 2.1 1.3 49.8 0.5 0.0 1.3 1.5 9.0 5.9 14.1 1.4 0.7 1.6 2.0 25.8 38.7 MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749192-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 409.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.5;MAIT T-cell: 3.0;memory CD4 T-cell: 1.8;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.5" "Cell line enhanced" "Detected in many" "RT4: 103.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB010762: AB_477166, HPA035482: , HPA035483: AB_2674647" "unprognostic (6.29e-2)" "unprognostic (6.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.30e-1)" "unprognostic (8.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-2)" "unprognostic (1.23e-2)" "unprognostic (2.66e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-2)" "prognostic favorable (1.27e-12)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.49e-2)" 9.9 9.5 18.6 7.1 29.3 0.3 28.3 22.6 32.0 18.5 32.6 22.1 33.0 7.6 22.9 32.0 11.5 27.0 5.3 19.6 19.5 51.4 15.2 23.2 4.7 23.7 24.4 4.7 21.6 40.4 14.5 7.6 24.3 17.2 19.2 49.0 25.9 19.9 3.4 16.8 33.9 5.7 16.0 7.6 27.6 14.6 23.9 5.1 15.9 3.1 12.8 24.0 15.8 34.6 52.2 13.0 12.3 8.9 29.7 23.7 42.6 20.7 23.6 12.3 18.3 22.2 44.2 0.1 16.1 25.7 14.0 40.0 15.3 29.2 18.6 17.0 30.3 17.4 5.6 14.1 25.0 0.0 22.2 17.5 21.6 19.3 14.5 24.0 43.3 7.9 22.4 7.2 15.4 48.3 0.2 0.8 7.7 44.1 3.8 0.7 29.1 1.6 51.1 103.6 26.8 14.8 5.6 46.6 6.8 28.3 16.5 35.8 59.4 13.7 9.3 0.6 20.0 13.2 16.1 0.3 10.9 0.2 5.3 0.2 0.1 0.1 5.5 0.0 3.0 0.2 1.8 3.1 0.0 0.1 0.4 3.0 0.6 2.9 0.1 0.1 0.2 0.8 18.6 29.3 22.6 32.0 19.6 19.5 23.7 24.4 24.3 16.0 23.9 34.6 74.8 141.1 207.0 286.3 4.7 30.1 87.5 49.2 18.2 83.6 99.6 35.9 8.1 38.6 91.3 150.8 120.9 32.0 14.7 112.2 54.8 128.9 7.0 86.9 26.9 57.2 85.0 0.0 147.8 120.3 23.8 30.5 91.7 169.2 26.0 81.0 37.9 33.8 6.3 95.9 167.2 76.4 116.0 2.9 6.1 9.6 30.1 6.7 30.2 105.9 2.7 307.3 12.3 179.4 409.1 197.0 99.7 43.2 11.4 165.9 105.7 97.6 109.5 188.4 13.1 26.5 32.7 14.4 32.1 28.3 34.1 78.4 13.4 191.8 77.5 199.7 MYO7A "DFNA11, DFNB2, NSRD2, USH1B" ENSG00000137474 "Myosin VIIA" Q13402 11 77128246-77215241 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Leber congenital amaurosis, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 41.9;choroid plexus: 53.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.9;Cytotrophoblasts: 42.3;Hofbauer cells: 30.1;Kupffer cells: 17.8;Rod photoreceptor cells: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.6;intermediate monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.6" "Cell line enhanced" "Detected in some" "BEWO: 11.8;CACO-2: 9.0;RH-30: 19.5;RPMI-8226: 13.8;SK-BR-3: 10.5;U-937: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB034059 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB034059: AB_2148626" "unprognostic (1.14e-3)" "unprognostic (2.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (4.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (3.03e-2)" 5.2 41.9 2.5 3.0 2.9 1.0 3.1 2.2 2.7 1.9 53.2 2.8 2.2 1.5 1.2 1.0 2.7 2.8 2.5 4.0 8.6 4.3 23.3 2.3 2.9 5.0 8.3 5.2 5.4 0.5 19.1 16.0 8.4 2.4 1.2 27.4 1.5 0.8 1.4 0.8 2.8 2.2 3.5 15.8 2.2 24.5 5.1 1.4 2.0 0.7 1.1 2.0 1.6 4.4 0.0 1.3 0.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 9.0 2.0 0.0 2.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.7 0.0 0.3 5.7 0.2 0.4 0.0 0.1 0.0 0.0 0.5 0.0 3.9 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.6 1.2 0.3 0.0 19.5 13.8 0.0 0.3 2.9 0.9 0.1 10.5 0.1 2.2 1.3 1.3 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 2.6 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.8 2.5 2.9 2.2 2.7 4.0 8.6 5.0 8.3 8.4 3.5 5.1 4.4 1.7 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.0 14.2 0.5 0.5 4.4 4.3 0.0 0.0 47.9 42.3 0.3 0.2 0.0 0.6 1.9 0.1 0.5 2.2 1.2 0.0 0.7 1.7 10.5 1.4 5.6 0.3 0.0 0.8 16.4 16.1 30.1 0.0 0.8 0.7 0.0 17.8 0.9 6.4 3.1 7.3 0.0 6.5 0.8 17.0 0.0 3.0 0.1 0.7 0.2 0.4 0.1 0.1 1.7 2.7 0.1 31.4 0.0 5.2 0.3 0.4 0.6 0.1 0.3 16.1 1.4 3.2 0.6 0.2 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYOT "LGMD1, LGMD1A, TTID" ENSG00000120729 Myotilin Q9UBF9 5 137867858-137887851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "skeletal muscle: 2183.8;tongue: 2038.6" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 40.9;Skeletal myocytes: 42.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037733, HPA037734" Enhanced NA NA 9100 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA037733: AB_10697082, HPA037734: AB_2675638" "unprognostic (5.85e-2)" "unprognostic (2.38e-2)" "unprognostic (6.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (8.03e-2)" "unprognostic (1.17e-2)" "unprognostic (1.54e-2)" "unprognostic (2.02e-2)" "unprognostic (6.44e-2)" "unprognostic (1.14e-1)" "unprognostic (7.56e-4)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.10e-1)" "unprognostic (1.40e-1)" 0.8 1.7 5.7 1.4 9.3 0.0 0.8 5.8 9.8 3.3 3.9 8.0 2.1 0.4 0.5 34.6 0.7 0.7 17.0 5.4 5.8 0.9 0.4 0.2 0.1 6.2 7.2 0.4 0.4 1.1 0.5 0.0 6.0 20.0 1.6 0.5 19.4 3.7 2183.8 1.0 3.1 1.0 5.3 0.6 1.9 0.2 6.8 0.2 1.0 2038.6 0.3 2.3 3.7 7.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 9.3 5.8 9.8 5.4 5.8 6.2 7.2 6.0 5.3 6.8 7.8 0.0 0.0 0.0 0.3 0.2 0.3 0.6 0.0 1.2 0.0 0.0 0.1 40.9 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.7 0.0 0.0 2.3 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.7 0.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.9 0.5 3.6 0.0 0.0 0.0 0.0 2.0 8.2 0.0 0.1 0.0 0.1 0.3 0.3 0.2 0.1 0.8 0.0 42.0 1.3 0.2 0.2 0.2 0.0 0.0 0.3 0.1 0.5 0.1 MYOZ1 "CS-2, FATZ, MYOZ" ENSG00000177791 "Myozenin 1" Q9NP98 10 73631612-73641474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 82 "skeletal muscle: 7134.0;tongue: 3308.1" "Cell type enriched" "Detected in some" 11 "Skeletal myocytes: 144.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BEWO: 44.6" "Region enriched" "Detected in single" 17 "olfactory bulb: 3.9" "Low region specificity" "Detected in all" "HPA037848, HPA038437" Enhanced NA NA 71000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA037848: AB_10670156, HPA038437: AB_2676009" "unprognostic (4.55e-2)" "unprognostic (2.23e-1)" "unprognostic (4.90e-2)" "unprognostic (3.91e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (2.76e-2)" "unprognostic (1.22e-4)" "unprognostic (1.18e-1)" "unprognostic (9.25e-2)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (5.14e-2)" "unprognostic (2.64e-2)" "unprognostic (6.78e-2)" "unprognostic (7.17e-2)" "unprognostic (1.09e-1)" 3.0 0.7 2.9 0.2 3.1 0.0 2.6 2.8 3.9 1.4 2.6 0.7 0.0 1.0 23.2 63.9 1.5 1.4 45.2 2.6 3.4 2.9 0.6 5.0 0.4 3.0 2.8 1.8 0.6 0.2 2.7 2.2 3.0 22.1 0.3 1.1 36.9 3.4 7134.0 2.1 0.5 0.9 2.9 1.6 0.6 2.1 3.0 0.9 4.4 3308.1 0.4 0.9 1.6 3.0 0.0 0.0 0.3 0.0 0.0 0.0 44.6 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 7.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.1 2.8 3.9 2.6 3.4 3.0 2.8 3.0 2.9 3.0 3.0 0.2 0.0 0.0 0.3 0.0 0.3 1.6 0.3 0.6 2.7 1.0 1.9 9.3 0.0 1.3 5.5 0.0 0.4 0.0 0.0 7.9 0.1 0.1 0.0 0.3 0.6 0.0 0.0 0.1 0.2 2.5 1.5 0.0 0.0 0.0 0.9 0.0 0.0 6.3 0.0 0.1 0.0 2.0 0.0 0.8 1.2 0.9 0.7 0.0 0.0 0.0 6.1 0.0 0.5 0.1 0.0 0.0 7.5 0.0 0.3 0.0 0.4 0.1 0.6 13.1 144.4 11.6 0.4 2.2 0.1 0.3 0.1 0.6 3.0 0.0 0.3 MYSM1 KIAA1915 ENSG00000162601 "Myb like, SWIRM and MPN domains 1" Q5VVJ2 1 58643440-58700077 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Immunity, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054291, HPA057306" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA054291: AB_2682438, HPA057306: " "unprognostic (2.95e-3)" "unprognostic (3.64e-2)" "unprognostic (3.20e-2)" "unprognostic (8.68e-2)" "unprognostic (2.08e-2)" "prognostic favorable (5.09e-5)" "unprognostic (8.12e-3)" "unprognostic (9.63e-3)" "unprognostic (5.72e-3)" "unprognostic (3.74e-1)" "unprognostic (2.25e-1)" "unprognostic (4.56e-2)" "unprognostic (2.38e-3)" "unprognostic (4.22e-2)" "unprognostic (1.83e-1)" "unprognostic (8.45e-2)" "unprognostic (1.44e-2)" 11.2 7.5 4.0 4.4 3.9 12.5 12.0 4.3 5.9 11.9 4.2 11.8 5.4 10.6 6.2 10.0 10.2 3.1 10.5 4.1 3.9 7.2 8.0 10.1 6.3 3.9 3.7 13.2 12.1 5.9 8.7 4.4 3.9 9.6 4.4 8.4 11.8 4.1 10.0 10.5 12.6 3.6 3.7 11.4 9.9 4.4 3.9 5.3 11.5 3.1 4.9 9.3 11.1 4.4 10.1 2.6 5.0 6.7 6.0 7.2 10.5 5.9 5.6 5.1 3.9 5.3 4.2 10.3 1.8 3.8 4.8 7.4 7.7 2.1 11.0 6.2 4.3 11.3 2.1 5.1 7.4 19.6 9.7 5.4 5.9 7.5 3.8 6.1 1.2 4.2 12.6 6.3 6.8 2.6 7.8 16.3 11.4 3.5 3.5 7.3 16.4 6.1 4.6 3.8 5.8 6.6 4.4 9.4 13.9 9.0 3.1 10.6 4.9 9.3 4.6 6.4 11.3 10.8 5.8 13.9 5.8 13.7 11.6 0.9 0.3 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.1 0.3 0.5 0.4 1.0 0.1 0.5 0.4 0.4 0.1 4.0 3.9 4.3 5.9 4.1 3.9 3.9 3.7 3.9 3.7 3.9 4.4 36.5 22.4 33.7 47.7 26.0 19.1 22.8 13.5 30.7 19.5 25.6 21.0 28.2 10.0 35.1 11.0 25.0 8.4 36.6 22.1 15.6 8.8 3.9 22.1 34.8 25.4 16.2 14.1 87.4 9.4 5.7 20.8 19.9 36.9 56.3 30.1 23.9 16.3 11.3 18.5 58.2 17.0 24.4 13.9 14.2 6.3 12.8 22.2 8.8 35.6 21.3 12.7 22.6 58.3 106.9 12.7 13.1 17.3 29.5 19.3 19.2 8.8 21.2 27.8 26.3 28.8 21.5 15.5 20.6 25.0 18.5 11.4 30.8 22.0 18.5 26.4 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.4;retina: 40.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Excitatory neurons: 27.9;Horizontal cells: 62.2;Inhibitory neurons: 57.1" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cell line enhanced" "Detected in some" "AF22: 13.6;HAP1: 13.2;NTERA-2: 24.0;SuSa: 20.7;U-2197: 16.1" "Low region specificity" "Detected in all" HPA026075 Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA026075: AB_1854301" "unprognostic (7.18e-2)" "unprognostic (1.81e-2)" "unprognostic (9.26e-2)" "unprognostic (4.83e-4)" "unprognostic (3.06e-1)" "unprognostic (1.28e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.75e-3)" "unprognostic (5.01e-2)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-4)" 2.5 13.4 65.2 2.8 53.3 1.2 2.6 46.9 103.4 19.3 11.2 3.2 1.5 12.1 5.6 1.3 10.0 5.4 11.3 50.5 62.9 3.3 1.3 1.8 2.5 45.3 62.7 16.7 1.3 1.0 18.1 1.5 54.4 4.4 2.4 40.9 1.4 5.3 0.4 1.7 2.0 8.2 40.6 4.6 1.4 16.6 46.9 1.1 5.6 1.2 1.3 3.5 2.8 47.5 0.0 0.2 13.6 9.9 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 7.6 0.3 0.1 13.2 0.0 0.0 0.0 0.3 6.4 0.0 0.2 0.7 0.0 0.4 6.1 0.0 0.6 6.2 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 24.0 0.0 5.7 0.0 10.5 0.0 0.4 0.1 0.1 1.4 0.0 0.0 0.2 20.7 0.0 0.7 0.0 7.5 10.9 16.1 0.7 10.2 4.5 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.7 0.0 2.6 0.9 0.0 0.0 4.1 2.9 0.1 3.1 0.0 0.0 0.8 0.9 65.2 53.3 46.9 103.4 50.5 62.9 45.3 62.7 54.4 40.6 46.9 47.5 0.8 0.0 0.0 11.8 0.3 0.6 0.3 0.0 0.0 41.8 0.2 1.9 8.3 0.0 0.6 0.0 6.2 0.2 0.8 0.0 17.6 0.1 1.2 0.3 9.9 1.4 0.0 1.3 27.9 0.0 0.2 7.6 0.0 0.3 5.7 7.4 1.1 0.0 0.4 62.2 57.1 0.0 0.0 0.0 0.9 2.2 11.8 0.3 5.4 9.4 0.2 16.6 0.0 16.6 21.2 0.2 0.0 19.5 0.1 0.0 0.0 0.5 1.5 12.9 0.0 6.6 4.0 5.7 7.4 0.0 0.4 0.3 1.6 16.4 0.0 0.0 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.3;tongue: 727.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1711.2;Distal tubular cells: 1064.4;Proximal tubular cells: 780.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" 119.4 114.4 151.2 88.9 152.7 79.7 105.5 165.7 227.5 69.9 161.9 185.7 136.7 46.4 132.2 98.4 66.1 66.3 389.3 151.5 165.1 247.1 195.3 63.5 103.7 158.2 155.4 46.2 54.7 219.3 57.8 78.0 158.1 77.1 174.6 140.8 100.8 75.8 704.3 52.0 127.9 73.8 157.2 61.6 115.5 83.1 158.2 143.4 96.0 727.7 128.8 95.4 53.7 160.6 180.1 148.9 227.5 122.0 226.3 207.0 183.1 224.8 160.1 171.9 200.3 347.2 211.3 144.4 249.8 211.4 261.9 154.5 209.6 287.7 269.4 294.5 460.6 349.0 363.8 394.8 141.2 500.9 170.5 180.1 223.6 203.3 119.2 211.3 250.3 259.2 311.1 240.3 313.1 234.4 313.8 459.8 129.9 392.4 536.7 215.6 200.4 388.0 380.6 278.7 209.5 150.1 176.0 153.2 258.2 353.2 150.7 373.0 227.3 144.8 179.7 150.9 222.8 174.5 435.3 452.6 246.0 284.4 172.6 205.2 135.4 159.4 116.1 205.3 129.2 148.8 132.7 135.7 177.3 117.3 115.2 140.9 267.3 141.6 213.3 211.8 183.1 109.6 151.2 152.7 165.7 227.5 151.5 165.1 158.2 155.4 158.1 157.2 158.2 160.6 95.3 80.1 57.7 18.9 100.9 78.1 100.0 433.7 66.6 52.9 101.7 128.1 1711.2 141.5 205.1 187.6 12.5 254.6 83.5 473.9 1064.4 247.0 218.1 191.6 93.9 101.9 146.4 113.8 13.2 201.7 208.9 103.4 118.7 135.2 78.0 61.0 86.7 260.5 288.2 32.0 14.7 299.0 248.2 121.6 107.1 59.9 95.4 126.8 168.9 10.3 292.9 184.6 116.4 7.5 19.9 177.3 411.0 101.5 135.2 72.5 496.3 780.3 229.2 92.0 92.1 82.3 125.4 270.0 89.7 169.2 91.9 157.6 89.7 113.9 322.1 132.9 NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 83.5;skeletal muscle: 268.3;tongue: 158.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1840.3;Distal tubular cells: 1136.7;Proximal tubular cells: 1449.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Approved Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" 9.5 15.3 19.9 8.0 20.4 9.1 11.0 22.4 28.6 7.4 21.3 18.6 23.8 8.1 14.3 10.5 10.5 5.4 83.5 19.6 20.8 26.7 24.1 8.8 10.1 20.3 21.0 10.0 14.8 22.9 15.8 5.9 21.6 9.7 19.0 23.5 18.9 14.4 268.3 13.2 18.6 7.4 19.5 10.4 17.0 12.7 20.5 8.6 14.8 158.5 11.0 8.6 7.9 22.4 21.4 5.9 19.2 30.8 17.7 22.7 20.5 20.1 13.1 11.1 10.4 13.1 23.7 7.7 7.7 15.5 14.9 10.5 38.6 18.2 15.0 13.0 13.5 11.9 13.5 23.0 18.1 11.2 10.1 24.5 18.2 14.4 21.6 16.8 17.5 17.8 25.3 33.8 11.0 17.8 17.8 32.1 16.3 44.1 11.7 14.9 10.6 52.6 24.6 14.2 14.6 14.7 13.8 23.2 10.5 15.6 23.7 23.2 8.1 24.2 6.4 13.0 13.5 23.2 49.5 18.5 18.9 26.7 13.8 26.2 10.1 13.1 8.5 10.3 11.6 7.1 11.7 11.5 8.9 15.9 10.5 11.4 3.0 10.1 14.2 16.2 18.2 10.8 19.9 20.4 22.4 28.6 19.6 20.8 20.3 21.0 21.6 19.5 20.5 22.4 201.8 89.8 145.7 15.7 95.8 140.2 173.3 402.7 185.0 120.4 240.3 349.6 1840.3 221.6 240.1 439.6 33.3 147.4 71.7 343.0 1136.7 270.3 409.9 333.5 115.5 162.7 221.4 175.2 10.9 336.9 166.2 176.9 158.0 196.8 73.3 151.2 133.5 432.9 225.1 119.5 14.3 340.5 276.7 102.0 65.7 70.9 169.3 115.6 266.8 6.5 185.5 446.6 79.3 8.0 13.3 265.3 355.8 206.5 155.6 173.7 471.7 1449.6 297.1 139.1 98.6 159.3 184.4 439.0 197.4 290.1 179.3 118.1 83.5 224.7 343.7 176.0 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NEDD1 "GCP-WD, TUBGCP7" ENSG00000139350 "NEDD1 gamma-tubulin ring complex targeting factor" Q8NHV4 12 96907224-96953780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 255.8;Late spermatids: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 133.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038591 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Centrosome" "HPA038591: AB_10674688" "unprognostic (7.93e-2)" "unprognostic (3.18e-1)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (2.21e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (1.94e-4)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.81e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.56e-1)" "unprognostic (2.46e-3)" "unprognostic (7.29e-2)" "unprognostic (2.28e-1)" "unprognostic (1.34e-1)" "unprognostic (5.59e-2)" 9.1 5.8 3.4 9.7 4.3 15.2 12.8 4.0 3.9 9.9 7.7 8.3 7.1 12.7 6.4 10.0 9.1 7.5 9.2 3.1 4.7 8.9 6.3 8.8 15.4 5.0 4.5 9.8 7.1 14.9 3.8 11.0 4.7 10.6 9.7 7.2 6.8 8.2 38.0 8.2 6.9 13.1 4.8 13.4 7.2 23.6 3.7 22.5 10.5 25.6 15.2 9.6 6.1 6.3 39.4 25.8 43.3 26.8 21.1 19.0 30.7 133.1 47.0 60.5 51.7 17.0 14.2 24.1 12.6 107.7 28.8 34.5 29.5 31.0 80.7 46.7 26.2 30.2 16.1 15.1 17.5 41.8 26.2 14.1 24.9 37.2 28.3 39.8 30.0 41.0 17.8 17.3 43.9 16.3 76.1 19.0 23.8 20.6 80.8 40.0 43.7 24.0 25.0 25.7 13.4 23.6 37.4 20.9 23.7 33.5 28.2 14.6 21.5 38.0 28.8 27.2 31.9 17.0 22.0 32.3 11.7 20.9 46.7 14.1 8.5 25.6 13.8 13.8 15.8 11.1 15.4 15.0 7.4 10.4 15.7 12.5 6.3 19.9 10.2 5.7 17.8 9.4 3.4 4.3 4.0 3.9 3.1 4.7 5.0 4.5 4.7 4.8 3.7 6.3 18.8 9.6 11.5 11.4 19.1 19.4 28.1 7.3 13.1 8.0 10.4 6.9 10.5 21.5 11.9 16.5 0.0 8.2 20.5 6.3 9.8 9.8 255.8 15.3 10.0 14.6 6.1 34.1 3.7 8.2 13.9 13.3 8.6 9.7 16.5 9.3 15.0 4.8 8.6 18.5 3.0 7.5 4.1 8.1 9.2 92.0 12.5 9.4 7.2 15.9 7.5 11.5 17.5 9.0 15.1 8.3 8.3 10.1 13.3 49.6 4.7 11.2 21.8 8.4 19.7 13.9 13.6 34.3 26.0 12.0 14.1 4.0 24.6 9.8 8.0 18.3 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.2;Oligodendrocytes: 140.9;Skeletal myocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 149.5;fHDF/TERT166: 211.3;U-138 MG: 191.5;U-2197: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA007533: AB_2667855" "unprognostic (3.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.84e-1)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (8.12e-2)" "prognostic favorable (4.66e-4)" "prognostic favorable (2.35e-4)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.92e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-2)" 76.4 14.9 30.4 19.7 80.2 14.9 48.0 99.8 97.7 67.2 4.0 60.4 20.9 88.5 10.9 72.4 69.5 53.9 60.9 54.0 15.0 8.9 20.3 50.0 6.2 50.9 45.1 73.8 23.8 13.2 18.9 11.8 39.4 85.0 19.7 11.7 150.4 60.0 410.3 99.2 24.3 67.8 45.6 11.3 37.3 16.0 46.9 11.6 31.0 138.2 6.2 45.0 52.7 105.2 39.2 16.2 1.0 119.9 111.7 149.5 1.3 48.1 68.6 45.7 31.8 1.3 3.3 0.6 13.4 211.3 31.4 17.5 12.8 37.4 20.1 25.8 19.7 20.2 7.6 17.2 53.8 8.5 10.3 99.0 10.9 44.1 24.6 80.3 12.4 8.6 6.7 6.2 29.3 12.1 14.9 5.7 0.5 8.6 132.3 43.5 22.2 23.1 0.4 8.5 17.9 47.6 34.5 0.3 43.0 0.0 22.7 17.3 12.2 191.5 23.5 185.1 68.5 4.5 1.7 0.3 49.9 12.1 62.0 0.1 0.1 0.0 0.5 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 30.4 80.2 99.8 97.7 54.0 15.0 50.9 45.1 39.4 45.6 46.9 105.2 19.5 12.8 59.3 62.7 6.8 58.8 45.5 22.4 134.9 13.3 57.9 74.2 33.2 27.1 15.9 14.7 4.2 0.2 3.7 16.5 1.9 24.3 64.0 12.1 40.1 20.0 12.1 145.2 69.0 12.7 0.3 89.7 32.6 3.0 3.8 4.3 17.9 33.9 1.0 0.0 38.1 25.8 2.0 4.1 15.2 43.1 112.2 5.8 26.6 17.8 1.9 93.7 0.0 52.3 140.9 15.2 12.0 126.0 2.5 60.3 8.4 10.0 19.0 3.0 6.6 174.7 38.3 15.6 13.2 99.4 51.4 0.3 3.8 56.0 29.5 31.8 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.4;Basal squamous epithelial cells: 36.5;Ionocytes: 89.5;Leydig cells: 96.0;Muller glia cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Group enriched" "Detected in some" 7 "RH-30: 200.1;WM-115: 225.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" 36.8 20.7 4.1 8.2 12.1 0.4 20.3 17.3 63.6 13.1 1.4 16.8 2.4 12.0 4.0 6.5 20.2 9.4 40.9 3.2 25.1 8.0 22.8 2.9 5.0 16.9 15.2 4.1 10.9 1.3 10.5 14.7 15.1 19.1 2.4 45.1 21.2 7.6 4.8 15.9 8.0 8.2 10.9 23.0 7.9 7.7 17.2 2.0 28.9 1.3 3.9 15.3 13.2 27.8 0.0 0.1 6.3 10.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.1 0.0 2.1 0.1 3.4 4.8 1.5 4.6 0.0 0.4 0.7 0.4 0.0 3.8 0.4 0.3 0.3 20.9 0.3 0.6 1.5 0.1 0.0 0.0 0.0 0.1 29.5 0.6 0.0 0.1 3.8 0.0 0.2 3.9 200.1 0.2 0.0 0.0 1.9 1.3 0.1 0.0 14.0 7.4 0.4 0.2 0.0 0.1 3.4 0.6 10.2 0.2 0.3 0.1 0.2 1.9 225.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 4.1 12.1 17.3 63.6 3.2 25.1 16.9 15.2 15.1 10.9 17.2 27.8 1.2 0.0 0.0 0.0 1.1 3.6 33.1 52.4 36.5 4.8 2.4 10.9 0.7 0.0 3.8 0.0 4.2 0.5 4.0 0.0 0.0 0.1 0.7 0.2 0.6 1.3 0.0 0.0 0.1 0.0 0.5 7.3 0.5 0.2 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 89.5 0.0 3.1 2.9 96.0 0.7 16.0 0.0 0.0 151.7 0.0 0.0 6.5 0.0 0.0 27.8 1.0 3.7 0.0 0.1 1.7 7.0 32.9 1.7 12.9 0.4 0.9 1.8 1.7 0.1 2.3 0.4 0.0 2.9 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NIPSNAP3B FLJ11275 ENSG00000165028 "Nipsnap homolog 3B" Q9BS92 9 104764129-104777764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.4;tongue: 19.5" "Cell type enhanced" "Detected in many" "Adipocytes: 11.8;Cardiomyocytes: 21.6;Excitatory neurons: 10.7;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "REH: 3.0;SH-SY5Y: 2.1;THP-1: 2.2;U-266/70: 2.3" HPA042491 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042491: AB_2678023" "unprognostic (1.72e-2)" "unprognostic (1.47e-2)" "unprognostic (9.76e-2)" "unprognostic (1.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (1.41e-3)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (4.25e-5)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (5.61e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (4.81e-2)" 6.6 5.1 1.8 1.1 1.9 0.7 4.3 1.2 2.2 2.3 1.6 1.1 0.5 3.1 3.4 1.0 1.9 1.3 12.8 1.9 2.0 1.5 0.5 1.4 1.5 1.5 1.5 3.3 1.9 1.0 2.7 3.0 1.6 2.7 0.9 2.5 1.4 3.6 20.4 1.3 1.2 1.6 1.2 2.0 1.1 1.0 1.8 0.8 2.0 19.5 1.8 0.9 1.5 1.5 0.0 0.3 0.4 0.1 0.4 0.4 0.7 0.1 0.2 0.2 0.1 0.3 0.3 0.8 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.0 0.5 1.4 1.2 0.1 0.4 0.2 0.4 0.4 0.1 0.3 0.0 0.5 0.1 0.7 1.2 0.0 0.0 0.2 0.6 1.2 0.2 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.9 2.1 1.2 0.0 0.1 0.2 1.1 2.2 0.1 0.2 0.4 0.2 0.1 2.3 0.8 0.2 0.0 0.2 0.0 2.8 0.0 0.6 0.0 0.1 0.1 0.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 1.8 1.9 1.2 2.2 1.9 2.0 1.5 1.5 1.6 1.2 1.8 1.5 11.8 0.0 1.1 2.0 8.5 0.4 1.5 0.8 1.2 4.0 0.9 1.7 21.6 0.0 0.3 3.7 0.0 0.8 0.1 0.0 5.9 0.7 0.0 2.2 2.0 3.4 1.2 5.9 10.7 0.2 0.2 3.9 2.6 1.2 1.3 2.5 6.1 0.3 6.2 0.0 9.8 0.3 4.1 0.9 3.9 0.9 2.5 3.0 0.0 16.9 4.1 1.2 0.0 4.5 1.1 0.2 0.0 6.8 2.3 0.3 0.0 0.4 3.2 0.5 0.0 2.0 3.7 0.8 1.1 1.7 0.9 0.8 1.1 0.8 0.2 0.2 NKAIN1 "FAM77C, FLJ12650" ENSG00000084628 "Sodium/potassium transporting ATPase interacting 1" Q4KMZ8 1 31179745-31239887 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adrenal gland: 24.2;brain: 19.9;skeletal muscle: 19.4;tongue: 11.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 43.9" "Group enriched" "Detected in many" 5 "breast cancer: 17.2;glioma: 4.6;prostate cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.2;AN3-CA: 35.8;NTERA-2: 92.7;SCLC-21H: 27.3;SH-SY5Y: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006873 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA006873: AB_1848410" "unprognostic (1.58e-2)" "unprognostic (7.99e-2)" "unprognostic (8.54e-2)" "unprognostic (6.11e-5)" "unprognostic (6.59e-2)" "unprognostic (1.24e-1)" "unprognostic (4.30e-4)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (2.78e-2)" "unprognostic (2.01e-2)" "unprognostic (8.07e-2)" "unprognostic (6.31e-9)" "unprognostic (1.00e-2)" "unprognostic (8.83e-3)" "unprognostic (1.62e-4)" "unprognostic (5.50e-2)" 0.1 24.2 8.1 0.2 15.6 0.0 0.4 17.3 11.6 0.3 3.1 0.3 0.1 0.6 3.4 0.6 0.1 0.0 0.0 11.5 10.6 0.2 0.0 0.0 0.0 17.9 16.4 0.1 0.2 0.6 2.2 0.3 19.9 1.0 0.1 1.5 0.4 0.3 19.4 1.7 0.1 0.2 6.8 0.0 0.1 0.3 12.2 0.2 0.0 11.9 0.0 0.0 0.5 18.6 0.0 0.4 21.2 35.8 0.2 0.0 0.3 0.1 0.0 0.4 0.1 0.4 0.2 0.0 0.7 0.4 0.4 0.0 5.3 0.0 0.1 0.0 1.5 0.0 0.3 0.3 0.2 0.4 0.1 0.1 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.3 0.8 92.7 0.0 0.9 0.0 0.3 0.1 0.1 3.6 27.3 43.9 1.0 0.3 2.5 2.4 9.6 0.4 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 15.6 17.3 11.6 11.5 10.6 17.9 16.4 19.9 6.8 12.2 18.6 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.9 0.2 0.0 0.1 1.1 0.0 0.0 0.0 3.6 0.0 0.3 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 3.3 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.5 43.9 0.1 0.0 0.0 0.0 0.3 0.0 0.8 0.1 0.5 0.0 0.3 0.3 0.8 1.2 0.3 1.4 0.4 0.0 0.1 0.0 0.2 NKAIN2 "FAM77B, TCBA1" ENSG00000188580 "Sodium/potassium transporting ATPase interacting 2" Q5VXU1 6 123803865-124825640 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 56.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1721.6;Inhibitory neurons: 636.4;Oligodendrocytes: 2869.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 3.0;HEL: 6.4;Karpas-707: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045860 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA045860: AB_10983192" "unprognostic (3.09e-2)" "unprognostic (1.06e-2)" "unprognostic (2.33e-2)" "unprognostic (4.53e-3)" "unprognostic (5.67e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.41e-3)" "unprognostic (2.02e-3)" "unprognostic (2.61e-1)" "unprognostic (5.95e-3)" "unprognostic (3.63e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (1.63e-1)" 0.9 0.4 24.2 0.1 33.6 0.7 0.3 30.1 39.3 0.3 9.8 1.0 0.0 0.1 0.3 0.2 0.3 0.2 1.1 29.2 25.3 0.1 0.2 0.2 0.2 40.7 28.0 0.1 0.1 0.0 1.8 0.1 37.4 0.2 0.1 6.6 0.3 0.2 2.9 0.1 0.3 0.3 34.8 0.1 0.2 0.4 28.8 0.5 0.1 3.4 0.2 0.5 0.3 56.8 0.0 0.0 1.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.4 0.0 0.0 0.4 0.0 0.0 1.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 10.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 33.6 30.1 39.3 29.2 25.3 40.7 28.0 37.4 34.8 28.8 56.8 0.5 0.0 0.0 97.3 0.0 0.1 0.0 0.2 0.0 3.0 0.0 0.1 1.3 0.0 0.1 0.0 2.1 0.2 0.0 0.0 0.0 0.1 1.7 0.2 0.1 0.3 1.8 2.1 1721.6 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 47.1 636.4 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.0 47.8 0.0 15.8 0.0 19.1 2869.5 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 567.3;Alveolar cells type 2: 566.9;Club cells: 217.6;granulocytes: 278.8;Late spermatids: 223.3;Respiratory ciliated cells: 250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA039077: AB_2676336, HPA057402: AB_2683427" "unprognostic (9.45e-3)" "prognostic favorable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 7.5 7.4 17.7 4.9 26.7 19.3 8.3 46.5 45.4 6.7 8.2 6.9 9.2 9.4 8.1 5.4 13.6 5.4 11.6 21.5 10.9 9.2 6.6 4.3 4.8 8.6 5.3 20.1 12.0 8.9 5.5 2.2 15.1 6.5 7.5 30.6 9.3 5.5 29.6 19.0 7.8 5.6 2.5 5.4 5.6 11.3 14.6 3.0 7.6 20.3 5.3 5.5 6.8 50.1 9.2 3.6 4.0 4.6 0.9 0.9 5.0 3.7 0.4 0.6 0.5 5.1 6.4 5.9 10.8 0.7 4.3 4.5 3.0 1.2 0.7 5.8 5.3 31.4 9.1 6.9 2.4 5.6 5.5 1.4 7.8 1.0 1.7 9.3 0.5 3.6 5.0 13.1 0.6 6.2 5.3 4.6 9.0 16.5 3.7 4.4 4.5 4.3 1.2 6.3 9.2 5.4 9.2 4.8 3.3 7.3 12.6 15.6 5.6 5.7 12.6 7.2 5.5 23.1 11.0 4.2 3.8 9.0 5.4 11.4 3.6 2.2 2.8 3.4 1.9 2.7 2.4 2.4 2.8 4.5 3.4 3.6 7.0 4.0 3.4 2.9 1.6 1.7 17.7 26.7 46.5 45.4 21.5 10.9 8.6 5.3 15.1 2.5 14.6 50.1 5.5 567.3 566.9 34.9 1.9 4.1 6.3 6.6 6.2 2.7 8.2 7.1 9.7 8.6 217.6 9.2 4.2 0.4 0.8 2.3 11.7 3.3 128.2 2.1 2.4 38.8 6.7 27.1 37.2 3.1 0.2 38.3 3.1 1.7 278.8 9.7 2.5 2.7 2.0 1.7 26.0 6.5 8.2 4.1 2.9 223.3 7.8 31.8 7.2 12.2 1.8 12.3 0.0 46.8 16.9 0.8 2.9 6.4 0.7 6.1 3.5 16.1 250.6 18.5 6.6 13.2 3.8 67.1 3.5 4.4 9.7 0.1 21.5 5.9 10.6 4.8 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Early spermatids: 148.5;Endometrial ciliated cells: 136.3;Respiratory ciliated cells: 167.4;Spermatocytes: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA046093: AB_2679535, HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" 3.1 3.7 4.5 1.0 4.7 0.1 4.0 4.0 8.6 4.7 11.1 5.3 1.0 5.4 9.0 1.3 17.1 3.3 4.8 4.6 5.2 8.0 0.8 4.3 0.9 5.4 5.8 4.5 3.2 17.0 11.7 1.3 5.0 4.4 1.7 10.8 2.5 4.7 36.2 1.7 1.9 4.6 4.6 1.9 3.6 24.9 5.5 1.1 7.4 10.8 0.6 4.1 2.7 4.6 9.8 3.1 5.9 4.3 3.3 7.9 1.3 2.4 7.9 8.5 8.4 3.1 7.1 0.5 6.0 5.8 7.8 4.7 2.8 7.5 10.0 1.7 3.9 0.2 1.9 2.1 4.5 1.4 0.0 5.2 4.4 12.7 3.6 12.0 4.7 1.9 0.1 0.8 4.9 2.0 1.0 2.1 2.8 0.2 4.9 0.2 6.5 0.3 14.5 0.8 3.0 3.1 3.2 4.2 9.2 2.8 5.1 1.0 3.2 4.9 4.2 5.0 7.7 2.4 2.9 0.7 13.9 0.2 3.3 0.3 0.0 0.0 0.3 0.1 0.5 0.8 0.2 0.1 0.3 1.5 0.5 0.3 0.2 1.1 0.0 0.0 0.0 0.1 4.5 4.7 4.0 8.6 4.6 5.2 5.4 5.8 5.0 4.6 5.5 4.6 8.3 6.4 8.9 31.6 1.6 5.2 8.7 18.1 2.8 11.8 5.3 6.6 14.3 8.6 23.3 9.2 47.9 1.9 0.3 0.8 19.6 15.6 148.5 136.3 15.8 7.0 0.0 0.0 29.1 4.9 0.5 8.1 0.0 17.0 0.0 13.4 9.3 2.7 1.4 21.9 15.0 0.9 18.3 0.8 3.1 65.2 7.5 1.4 7.2 4.7 0.0 12.3 0.0 12.1 11.5 6.4 1.3 9.8 0.1 3.1 0.2 35.9 167.4 69.1 13.1 14.3 10.3 146.3 24.9 1.0 4.0 0.3 1.3 9.6 1.7 5.8 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 32.8;Excitatory neurons: 39.8;Hepatic stellate cells: 160.6;Sertoli cells: 46.0;Smooth muscle cells: 34.1" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HEL: 128.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 30.5 31.0 10.4 2.9 13.1 0.0 32.4 0.0 13.7 7.8 0.0 5.8 1.0 7.3 10.2 1.8 8.4 4.5 4.8 9.1 19.7 32.3 14.7 2.1 17.3 0.3 0.8 2.8 28.7 3.6 3.0 5.2 0.4 2.5 4.5 4.4 21.4 8.3 2.9 9.8 1.5 5.7 5.7 119.6 1.8 4.1 2.2 1.1 7.9 2.6 0.9 1.8 4.9 9.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 7.0 0.0 0.0 0.0 0.0 128.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 1.2 0.0 4.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.0 0.0 0.0 0.1 1.2 0.0 0.6 0.1 0.0 0.0 1.4 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 10.4 13.1 0.0 13.7 9.1 19.7 0.3 0.8 0.4 5.7 2.2 9.0 2.1 0.0 0.5 1.3 0.7 2.8 0.7 0.0 3.4 11.6 19.2 3.3 0.9 1.5 0.0 0.0 2.1 0.0 0.0 3.4 13.7 12.5 5.0 0.0 0.4 10.8 32.8 0.0 39.8 0.0 0.0 5.1 0.0 0.1 0.0 3.7 160.6 0.9 0.1 0.0 18.8 1.6 0.0 7.2 0.9 2.4 11.5 0.1 5.4 4.7 0.0 1.1 0.0 2.0 1.4 0.1 15.9 0.4 0.0 0.5 0.1 0.1 0.0 2.1 46.0 1.1 34.1 0.5 0.6 0.1 1.7 0.0 0.6 0.5 2.1 0.3 NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2363.9;tongue: 1144.8" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 534.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 8.2;prostate cancer: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: AB_2675755, HPA037954: AB_10672394, HPA075074: " "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (3.61e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (1.97e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-3)" "unprognostic (3.72e-2)" "unprognostic (4.20e-2)" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (5.39e-4)" "unprognostic (8.21e-2)" "unprognostic (1.16e-1)" "unprognostic (3.16e-1)" 0.3 0.1 0.1 0.0 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 24.8 0.0 0.2 428.6 0.2 0.0 0.1 0.5 0.4 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 20.4 1.0 0.0 22.1 0.0 2363.9 0.8 0.1 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.4 1144.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 534.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.1 0.0 3.7 0.0 0.0 0.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 4.8 0.0 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 57.3 3.3 1.0 2.3 0.0 0.1 0.0 0.2 0.0 0.5 0.0 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.1;ovary: 32.5;placenta: 24.2" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 79.4;Leydig cells: 113.4;Syncytiotrophoblasts: 67.9;Theca cells: 70.2" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 11 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 58.1;HSkMC: 10.6;RH-30: 12.8;RPTEC TERT1: 34.8;SuSa: 40.5" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 41.6" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 0.8 16.1 0.0 0.9 0.0 0.0 0.7 7.0 0.3 1.8 0.0 1.4 0.1 1.7 4.6 0.6 0.9 10.1 3.5 0.0 0.1 6.2 0.1 0.2 0.0 0.1 0.6 32.5 0.4 0.1 0.3 24.2 0.5 4.9 0.3 0.1 1.1 0.9 0.2 0.1 0.3 1.7 0.1 0.0 0.5 3.3 0.0 0.1 0.2 3.3 0.0 1.0 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 10.6 0.0 0.1 0.0 3.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 12.8 0.0 34.8 0.7 0.0 0.2 0.0 1.8 0.0 40.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.1 0.1 0.6 0.5 0.1 0.0 0.4 3.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 1.2 1.0 4.8 0.0 0.0 0.0 0.0 79.4 0.0 0.2 19.6 0.2 1.3 0.0 3.2 0.7 0.0 0.0 0.9 0.0 10.1 8.9 0.0 0.0 0.0 2.1 0.0 0.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 2.6 113.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 13.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.7 1.6 1.7 0.1 0.0 67.9 0.0 70.2 0.2 0.1 NRXN2 ENSG00000110076 "Neurexin 2" "P58401, Q9P2S2" 11 64606174-64723197 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.4;Horizontal cells: 149.7;Inhibitory neurons: 47.8;Late spermatids: 49.7;Muller glia cells: 60.7;Oligodendrocyte precursor cells: 47.3;Peritubular cells: 59.0" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 47.8;SCLC-21H: 22.8;SH-SY5Y: 10.5;U-2 OS: 26.1;U-87 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1000000 "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.87e-2)" "unprognostic (1.54e-4)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "unprognostic (8.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (5.08e-2)" "unprognostic (3.23e-1)" "unprognostic (5.93e-3)" "unprognostic (3.40e-1)" "unprognostic (9.97e-3)" "unprognostic (2.39e-2)" "unprognostic (6.99e-2)" "unprognostic (4.27e-4)" "unprognostic (5.46e-3)" 3.8 4.7 61.0 2.0 51.6 0.5 2.6 73.6 65.9 27.0 0.0 17.1 1.0 19.0 1.1 0.4 14.6 2.2 3.7 61.9 21.8 5.8 1.0 1.5 1.0 16.0 18.2 15.5 3.0 0.1 4.3 0.7 11.6 4.9 0.6 13.0 1.6 2.9 1.1 0.9 2.7 2.4 4.6 1.5 2.4 15.3 24.8 0.8 4.0 0.3 0.4 5.9 7.4 18.3 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.3 0.3 2.5 2.0 0.1 3.3 0.0 0.0 0.3 0.4 6.5 0.0 0.0 0.0 0.0 0.5 1.2 0.0 4.5 0.0 0.0 0.0 0.1 0.0 9.0 3.1 0.0 0.7 0.3 7.6 0.0 0.0 47.8 1.4 1.9 0.0 0.0 22.8 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.3 1.1 26.1 0.5 0.0 0.0 0.0 0.0 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 61.0 51.6 73.6 65.9 61.9 21.8 16.0 18.2 11.6 4.6 24.8 18.3 0.5 0.0 0.0 13.1 0.0 0.5 0.1 0.0 0.0 72.4 0.2 0.6 3.2 0.0 0.0 1.8 6.2 0.1 0.6 6.3 3.9 0.0 23.6 0.9 23.5 2.5 6.7 2.1 36.0 2.7 0.2 7.3 0.0 0.6 0.0 0.7 2.9 8.6 0.2 149.7 47.8 1.1 0.0 1.2 0.7 49.7 42.6 1.2 0.0 7.5 0.7 60.7 6.2 47.3 26.0 0.4 2.5 59.0 0.0 0.1 5.1 40.9 0.0 21.7 0.0 27.3 4.0 37.5 15.2 0.0 0.1 0.3 0.7 4.9 0.9 0.0 NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39659121-39672038 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 72.4;tongue: 28.6" "Cell type enhanced" "Detected in single" "Inhibitory neurons: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "SH-SY5Y: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050283, HPA054158" Supported NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050283: AB_2681072, HPA054158: AB_2682402" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-1)" "unprognostic (1.51e-3)" "unprognostic (7.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.81e-2)" 0.2 2.6 1.4 0.1 0.8 0.0 0.0 4.8 5.4 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.2 0.0 11.4 0.7 1.6 0.4 0.0 0.0 0.0 3.0 3.1 0.1 3.9 0.0 0.0 0.0 2.0 0.5 0.0 0.1 0.1 0.1 72.4 0.0 0.1 0.1 1.4 0.0 0.1 0.2 2.2 0.1 0.0 28.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 17.8 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.8 4.8 5.4 0.7 1.6 3.0 3.1 2.0 1.4 2.2 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 321.8;choroid plexus: 89.2;retina: 74.8" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 608.9;Astrocytes: 2164.2;Cone photoreceptor cells: 950.8;Excitatory neurons: 651.0;Inhibitory neurons: 1056.6;Oligodendrocyte precursor cells: 1930.7;Oligodendrocytes: 1257.6;Rod photoreceptor cells: 1415.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.4" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.4" "Cell line enhanced" "Detected in many" "LHCN-M2: 122.4;U-138 MG: 47.7;U-2 OS: 81.8;WM-115: 166.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" NA NA 58000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB024875: " "unprognostic (1.52e-2)" "unprognostic (4.38e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-1)" "unprognostic (1.07e-1)" "unprognostic (9.99e-3)" "unprognostic (9.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.10e-8)" "unprognostic (4.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (9.31e-3)" 17.9 4.7 137.2 2.3 138.8 0.0 2.9 165.1 321.8 1.6 89.2 12.0 2.5 1.3 0.6 9.4 0.9 9.6 30.5 136.9 131.5 2.3 0.3 25.8 0.4 144.0 135.4 0.3 0.9 22.1 0.9 0.7 143.6 1.9 3.8 74.8 2.7 2.8 0.9 6.1 4.6 4.5 135.0 0.5 2.0 0.6 154.2 0.5 1.1 5.0 0.4 3.5 1.8 158.4 0.1 0.0 7.5 0.1 0.9 22.2 0.0 36.7 19.5 11.7 6.8 0.1 0.0 0.0 0.0 20.3 0.0 0.3 0.0 43.6 12.6 0.1 0.4 0.0 0.0 0.4 0.4 0.0 0.2 2.0 0.0 38.0 45.0 29.0 7.5 0.0 0.0 0.3 122.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 3.9 20.8 0.0 2.4 3.8 0.0 0.0 0.2 1.3 0.0 0.1 8.1 47.7 81.8 2.2 31.6 0.0 0.0 0.2 0.1 0.0 166.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 137.2 138.8 165.1 321.8 136.9 131.5 144.0 135.4 143.6 135.0 154.2 158.4 1.2 608.9 27.6 2164.2 0.0 1.8 0.0 1.5 2.2 225.3 0.9 4.4 13.7 0.0 29.7 20.2 950.8 0.0 5.4 0.4 0.0 0.6 10.9 0.0 0.5 2.9 0.0 2.7 651.0 0.0 0.0 22.2 0.5 0.0 53.0 0.1 0.7 0.0 0.1 40.4 1056.6 0.1 0.0 0.0 3.8 2.2 0.3 0.7 3.6 139.6 0.0 30.5 0.0 1930.7 1257.6 0.1 0.2 0.4 0.1 0.1 0.0 0.1 1.5 1415.0 0.0 20.6 7.5 0.4 0.9 0.5 4.8 0.0 0.8 0.0 0.8 0.1 NXF3 ENSG00000147206 "Nuclear RNA export factor 3" Q9H4D5 X 103075810-103093143 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 25.0;testis: 57.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Early spermatids: 2.4;Endometrial ciliated cells: 8.4;Hepatic stellate cells: 2.9;Kupffer cells: 2.6;Late spermatids: 4.2;Paneth cells: 3.9;Undifferentiated cells: 2.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 48.6;HL-60: 46.6;NB-4: 43.0;THP-1: 33.0;U-2197: 135.9;U-937: 101.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003132, HPA046757" Approved Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA003132: AB_1079514, HPA046757: AB_2679789" "unprognostic (1.20e-3)" "unprognostic (6.72e-2)" "unprognostic (2.74e-1)" "unprognostic (3.05e-2)" "unprognostic (6.75e-4)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (8.86e-2)" "unprognostic (6.19e-2)" "unprognostic (3.13e-2)" "unprognostic (3.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.21e-10)" "unprognostic (1.90e-2)" "unprognostic (4.51e-2)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" 0.6 0.8 0.0 0.1 0.0 3.9 0.2 0.0 0.1 1.4 0.1 0.3 0.6 0.1 10.9 0.1 25.0 7.2 0.4 0.0 0.0 1.1 1.1 4.9 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.9 0.0 1.1 0.1 0.0 0.1 3.0 0.0 0.0 0.6 0.1 57.8 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 0.2 0.0 0.0 0.1 0.5 0.2 0.0 48.6 0.5 0.0 0.0 46.6 0.0 0.0 0.0 1.9 0.0 0.6 0.0 2.2 0.0 8.6 1.0 0.0 0.2 43.0 0.0 0.4 0.2 0.0 0.9 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.0 0.0 0.0 0.1 135.9 0.1 0.1 0.0 0.0 0.7 101.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 2.4 8.4 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 2.9 0.0 0.5 0.0 0.1 0.9 0.0 2.6 0.0 4.2 0.3 1.4 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.6 3.9 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.0 0.1 0.8 1.6 0.0 0.0 0.0 0.0 0.0 2.8 0.0 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112905856-112933219 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 91.0;urinary bladder: 111.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 151.0;Hofbauer cells: 105.6;Paneth cells: 127.9;Urothelial cells: 171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 572.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 247.1;BJ hTERT+ SV40 Large T+ RasG12V: 336.6;OE19: 307.6;U-266/70: 272.9;U-266/84: 210.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favorable (6.12e-6)" 17.0 11.5 6.8 27.3 7.3 14.3 13.1 6.5 9.7 29.6 6.1 49.0 51.7 8.0 8.1 57.1 10.0 22.5 9.5 6.6 6.9 22.3 38.6 23.1 27.2 15.4 8.0 8.1 4.4 9.0 8.3 20.4 11.5 9.1 45.1 1.5 91.0 7.3 2.4 10.3 39.8 14.6 21.2 50.5 43.6 4.8 8.4 28.1 7.7 7.4 25.6 111.1 22.7 9.9 4.7 24.4 0.0 0.1 9.4 6.6 1.5 0.1 38.8 247.1 336.6 18.5 34.1 42.3 12.2 0.3 121.8 10.8 0.2 4.2 2.2 21.0 0.0 0.7 35.2 4.6 2.9 0.6 1.4 0.5 7.2 8.0 0.0 3.1 13.5 0.7 0.0 17.4 0.2 0.4 0.6 17.0 0.7 307.6 22.5 5.8 0.2 20.5 11.6 89.4 0.2 0.9 3.7 4.2 85.2 0.4 0.9 5.1 50.4 0.0 0.5 3.2 0.4 272.9 210.3 23.9 2.9 6.6 1.4 6.3 253.6 3.2 26.5 403.9 25.3 108.8 36.3 34.3 153.9 93.1 14.3 18.8 24.4 24.9 572.0 144.5 108.7 217.8 6.8 7.3 6.5 9.7 6.6 6.9 15.4 8.0 11.5 21.2 8.4 9.9 23.0 3.2 2.2 0.0 21.1 3.4 16.6 24.0 10.8 0.2 6.0 8.1 3.1 14.3 35.4 5.5 0.0 12.6 31.5 151.0 5.9 19.5 0.4 1.9 3.6 17.2 4.2 3.6 0.6 12.0 36.4 11.1 28.5 4.1 5.1 15.4 14.3 11.9 105.6 0.0 1.0 59.3 26.4 36.9 11.4 1.2 7.2 52.9 5.4 13.1 36.2 15.0 18.6 3.5 0.1 19.5 127.9 10.5 24.1 7.4 50.9 25.4 17.5 0.4 6.6 3.0 7.5 0.0 0.5 18.3 2.3 5.7 9.1 12.7 14.6 171.9 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like cytoskeletal adaptor 1" O75147 2 219550728-219571859 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 337.3" "Group enriched" "Detected in many" 8 "Early spermatids: 1140.1;Late spermatids: 1994.5;Spermatocytes: 572.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 11 "dendritic cells: 1.3;granulocytes: 4.4" "Cell line enhanced" "Detected in many" "BEWO: 155.2;SK-BR-3: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA036404: AB_10670437, HPA036405: AB_2675104" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 52.3 117.5 25.0 9.7 24.3 3.1 53.5 24.4 32.2 74.6 34.4 44.6 9.4 78.0 22.5 17.7 84.6 28.8 90.8 26.1 27.9 110.1 43.9 38.6 9.6 30.3 29.1 337.3 120.6 49.5 74.9 45.8 24.8 63.1 5.4 14.9 62.9 44.2 64.1 38.3 22.5 20.9 25.2 31.7 48.0 40.5 29.7 6.9 148.9 30.2 4.6 41.2 36.7 22.3 34.2 22.7 40.9 85.8 27.7 20.4 155.2 25.3 36.8 31.5 29.0 20.0 52.2 0.2 51.6 34.7 30.5 34.4 31.9 19.0 6.5 0.3 56.2 74.3 23.0 102.1 20.9 1.9 0.3 55.3 15.4 7.3 12.1 56.1 3.4 0.1 31.3 0.7 22.7 84.6 0.1 21.3 97.8 9.7 23.1 37.5 36.3 0.2 57.4 31.9 18.1 61.3 28.6 150.9 59.2 102.8 14.0 63.9 8.6 33.3 35.6 10.6 10.0 0.2 0.2 0.3 19.5 0.2 33.7 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 1.3 0.0 0.0 25.0 24.3 24.4 32.2 26.1 27.9 30.3 29.1 24.8 25.2 29.7 22.3 10.4 9.6 20.4 45.7 1.1 8.4 22.8 11.7 19.9 35.8 27.0 38.7 52.4 27.1 10.0 53.3 2.1 64.7 2.5 1.5 52.8 15.9 1140.1 19.5 33.0 11.4 20.4 0.0 21.1 12.5 69.7 30.1 6.6 21.7 4.5 152.8 11.4 15.4 7.7 42.1 43.3 3.7 6.1 1.0 3.9 1994.5 77.0 3.4 14.2 9.4 0.7 87.0 0.0 23.1 3.1 7.6 2.0 74.1 0.1 8.8 7.1 20.3 7.8 11.6 13.1 29.9 27.0 572.7 57.0 4.3 6.7 86.5 1.4 114.0 3.3 10.2 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OR51E2 PSGR ENSG00000167332 "Olfactory receptor family 51 subfamily E member 2" Q9H255 11 4680171-4697854 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 9.6;prostate: 28.9" "Cell type enriched" "Detected in some" 6 "Enteroendocrine cells: 77.4" "Cancer enriched" "Detected in some" 274 "prostate cancer: 217.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;BJ hTERT+: 1.1;hTERT-RPE1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.98e-3)" "unprognostic (1.91e-1)" "unprognostic (6.09e-3)" "unprognostic (1.57e-2)" "unprognostic (8.00e-4)" "unprognostic (3.61e-2)" "unprognostic (6.27e-2)" "unprognostic (1.66e-1)" "unprognostic (3.05e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-1)" "unprognostic (3.61e-1)" "unprognostic (5.04e-5)" "unprognostic (3.34e-2)" "unprognostic (4.66e-2)" "unprognostic (5.76e-2)" "unprognostic (3.29e-1)" 0.6 0.2 0.3 1.0 0.4 0.1 0.5 0.4 0.5 0.7 0.6 9.6 0.2 1.3 0.3 0.0 0.5 0.3 0.2 0.4 0.2 0.4 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.0 0.0 4.0 0.4 28.9 2.2 0.1 0.0 2.3 0.4 0.2 0.8 2.1 0.1 0.0 0.4 0.3 0.5 0.0 0.1 0.4 0.0 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.5 0.4 0.2 0.3 0.3 0.4 0.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 77.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 OTULINL "FAM105A, FLJ11127, NET20" ENSG00000145569 "OTU deubiquitinase with linear linkage specificity like" Q9NUU6 5 14581792-14616180 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 29.5;dendritic cells: 36.7;Endometrial stromal cells: 16.6;Hofbauer cells: 100.7;Macrophages: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 17.7;HMC-1: 55.6;OE19: 16.1;THP-1: 16.9;U-937: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046638 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli, Cytosol" "HPA046638: AB_2679731" "unprognostic (1.47e-1)" "unprognostic (6.64e-3)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (6.26e-2)" "unprognostic (1.13e-3)" "unprognostic (2.33e-2)" "unprognostic (2.27e-2)" "unprognostic (6.44e-2)" "unprognostic (2.42e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.13e-1)" "unprognostic (1.33e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (3.14e-1)" "unprognostic (8.79e-3)" 3.1 2.7 1.2 6.8 1.1 30.3 4.1 1.3 1.6 3.8 4.8 12.3 6.6 1.5 1.4 1.7 1.4 2.7 0.9 1.1 1.8 3.6 1.4 13.1 5.4 2.3 1.5 2.0 7.6 1.2 2.5 4.2 2.1 8.3 13.3 0.5 1.4 10.0 0.4 1.7 9.4 2.5 2.4 7.9 3.3 2.5 1.9 3.4 2.8 0.8 3.6 5.2 3.1 3.6 0.0 0.8 1.6 0.0 0.3 0.0 6.9 2.0 1.8 0.5 1.0 2.8 1.7 0.1 1.1 0.9 2.8 0.1 3.7 1.6 0.7 1.1 4.9 4.6 17.7 0.4 1.7 0.1 55.6 0.1 0.3 0.2 0.0 0.0 0.1 2.9 0.0 7.1 0.2 1.4 0.0 1.7 2.5 16.1 11.9 0.5 0.7 2.0 0.0 13.9 6.0 7.0 0.9 0.6 0.0 1.7 0.6 16.9 0.0 0.9 4.4 0.4 1.6 0.0 0.0 0.1 1.0 27.2 0.4 0.2 33.4 0.3 5.5 16.2 7.3 0.1 6.7 7.2 33.8 0.1 9.0 9.1 8.6 19.2 12.7 25.0 12.8 24.6 1.2 1.1 1.3 1.6 1.1 1.8 2.3 1.5 2.1 2.4 1.9 3.6 10.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 7.4 7.9 0.0 0.0 0.0 29.5 0.0 0.9 36.7 0.0 1.9 0.4 0.0 0.9 16.6 1.1 0.0 0.0 0.0 6.2 2.2 1.4 0.0 1.2 0.0 0.5 0.0 0.0 100.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 12.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 8.8 0.2 0.0 0.0 P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 156.7" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "Karpas-707: 40.0;RPMI-8226: 24.8;SK-MEL-30: 41.0;U-266/70: 21.7;U-266/84: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" 2.8 2.5 20.2 5.1 28.5 2.9 2.0 23.1 30.7 6.1 11.3 3.6 1.5 4.1 1.5 1.4 2.3 3.5 1.3 21.8 20.7 0.7 4.6 6.5 5.9 26.3 24.7 8.3 1.4 1.7 1.8 2.9 28.3 1.8 2.3 0.5 2.5 1.8 0.6 13.1 1.8 4.2 21.3 5.9 1.6 1.3 26.2 1.7 1.0 1.0 3.6 2.3 4.4 47.3 0.1 0.0 0.0 1.0 1.1 0.4 0.8 0.1 1.9 0.7 1.7 0.0 0.0 0.1 0.1 0.7 4.3 0.2 0.0 0.0 0.5 1.8 0.1 0.7 0.0 0.1 0.8 1.6 11.6 1.0 0.0 2.0 0.0 0.0 1.9 0.4 0.0 40.0 0.0 0.0 0.2 4.4 0.1 0.0 0.4 3.8 8.9 24.8 0.0 0.0 0.5 2.3 0.2 0.0 41.0 0.0 0.6 7.8 0.0 0.6 0.1 0.1 0.2 21.7 20.2 0.1 2.4 11.8 6.1 0.4 2.9 0.0 1.3 4.5 0.5 0.3 0.6 0.6 2.6 0.2 0.5 0.6 0.3 0.6 3.3 0.4 1.4 0.9 20.2 28.5 23.1 30.7 21.8 20.7 26.3 24.7 28.3 21.3 26.2 47.3 2.0 3.2 4.8 12.1 3.9 6.9 3.0 0.0 1.8 3.9 1.8 2.2 2.4 5.7 3.7 0.0 2.1 3.5 9.0 1.2 0.0 1.2 0.6 0.7 1.6 3.9 0.0 1.7 52.8 0.0 0.9 3.7 0.0 0.3 6.3 2.6 5.3 3.9 23.4 1.7 18.4 0.2 0.0 21.5 35.0 1.5 11.1 34.2 16.0 34.7 21.2 1.3 7.2 87.9 156.7 0.2 0.0 10.5 1.3 1.2 0.1 0.0 3.6 1.0 6.6 3.2 1.9 1.2 0.9 1.0 3.7 4.0 6.6 4.1 0.1 1.0 P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 25.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Cholangiocytes: 21.5;Distal enterocytes: 25.4;Kupffer cells: 21.1;Squamous epithelial cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.6" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.6" "Cell line enriched" "Detected in many" 5 "HEL: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015577 Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" 1.6 1.4 6.2 2.3 14.2 5.7 1.4 3.1 6.4 4.5 1.0 9.1 3.2 6.5 0.5 19.2 2.1 2.0 2.9 5.9 6.7 0.8 1.5 7.0 0.8 3.3 4.2 8.8 3.3 0.3 1.6 25.4 8.4 7.7 6.7 9.0 3.2 2.2 7.7 8.9 6.1 4.5 4.9 2.2 0.9 1.1 8.2 1.6 1.3 3.4 2.7 2.4 8.0 4.1 0.0 0.7 7.0 0.0 1.1 0.1 0.0 0.0 0.1 0.2 0.6 9.0 0.1 0.0 0.7 0.0 1.1 1.5 3.9 1.3 0.3 0.0 3.4 45.9 0.1 0.0 0.0 5.4 4.0 0.5 8.7 0.0 0.4 3.5 0.0 1.5 1.4 0.0 0.0 0.1 0.8 0.1 6.4 0.0 5.5 0.0 0.2 1.3 0.0 3.1 1.1 0.0 0.0 0.0 0.9 1.6 0.0 2.4 0.0 0.7 1.8 0.0 3.9 0.0 0.0 0.0 4.5 0.0 5.2 6.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.1 6.2 14.2 3.1 6.4 5.9 6.7 3.3 4.2 8.4 4.9 8.2 4.1 1.0 0.0 0.5 12.7 0.8 1.9 6.7 3.3 15.9 23.3 0.5 0.1 7.1 21.5 1.0 0.0 0.0 0.2 1.6 25.4 0.0 1.3 0.2 1.9 12.0 7.1 0.0 10.8 0.0 0.0 0.3 5.6 0.0 2.7 10.1 0.1 11.7 0.3 7.4 0.0 0.2 8.9 0.0 21.1 0.3 0.8 14.9 15.9 0.0 1.0 1.8 19.1 0.0 0.0 0.6 0.9 12.3 6.0 0.0 6.3 13.4 0.2 0.2 1.5 0.0 1.2 1.0 0.4 2.2 45.4 2.0 0.1 0.5 3.5 8.3 4.9 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.5 2.6 1.2 1.5 0.7 0.3 3.9 3.7 2.7 11.9 5.6 5.4 0.8 19.2 0.5 1.6 9.9 1.7 4.5 1.1 1.2 2.0 0.6 3.7 0.3 1.3 0.2 12.4 2.9 4.5 15.4 1.3 0.3 6.0 0.3 4.1 6.5 3.7 0.8 3.0 2.8 3.8 0.2 1.3 3.8 1.2 0.9 0.1 4.3 0.3 0.3 7.8 6.4 0.5 0.0 1.6 7.1 14.0 8.4 10.2 0.3 39.6 22.4 12.2 13.5 0.6 0.0 0.0 0.5 14.9 0.5 0.0 4.4 0.4 2.7 0.1 18.8 1.0 4.2 1.9 5.9 1.0 0.0 11.1 0.4 6.0 3.3 27.3 13.1 1.2 3.7 0.0 5.7 0.0 0.1 0.4 27.5 0.0 1.1 0.0 6.9 0.2 0.6 0.0 2.8 10.5 0.1 0.0 4.8 3.4 0.2 0.2 23.2 12.0 17.5 18.6 27.7 0.1 0.3 0.3 10.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 3.7 2.7 1.1 1.2 1.3 0.2 0.3 0.2 0.9 0.5 2.3 0.0 0.0 3.3 0.5 0.0 4.9 0.0 2.2 47.2 5.3 5.5 11.1 1.5 1.8 5.5 100.1 0.5 0.1 0.1 1.9 1.4 0.9 0.9 19.6 3.9 1.2 0.0 13.1 2.7 0.5 24.1 2.0 0.4 0.0 0.8 7.9 0.0 1.4 43.7 13.7 2.7 0.0 0.0 0.0 2.2 49.7 0.5 0.0 2.8 1.1 5.3 0.0 5.5 1.3 1.3 0.1 38.4 3.1 5.1 0.4 0.4 1.5 28.8 6.6 7.8 11.9 0.7 0.8 0.8 0.0 1.0 0.9 3.2 0.6 1.5 PABPC4L ENSG00000254535 "Poly(A) binding protein cytoplasmic 4 like" P0CB38 4 134196333-134201789 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 10.3" "Cell type enhanced" "Detected in some" "Adipocytes: 5.3;Endometrial ciliated cells: 7.4;Endometrial stromal cells: 5.7;Fibroblasts: 5.5;Glandular and luminal cells: 12.2;Leydig cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 11.4;HeLa: 15.8;REH: 8.1;RH-30: 8.5;U-2 OS: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.00e-1)" "unprognostic (3.53e-2)" "unprognostic (1.96e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (2.55e-3)" "unprognostic (1.58e-1)" "unprognostic (3.63e-1)" "unprognostic (9.05e-3)" "unprognostic (2.97e-1)" "unprognostic (9.52e-2)" "unprognostic (6.44e-2)" "prognostic favorable (1.11e-5)" "unprognostic (4.41e-3)" "unprognostic (1.82e-1)" "unprognostic (1.22e-1)" "unprognostic (4.14e-3)" 1.5 0.4 0.6 0.5 0.7 0.0 0.8 0.5 0.8 2.4 0.5 0.4 0.3 3.7 1.4 0.7 2.0 1.1 1.7 0.4 0.5 1.0 0.1 0.5 0.2 0.5 0.5 2.2 0.3 5.3 0.3 10.3 0.6 2.9 0.3 0.0 2.1 4.2 0.2 0.3 0.3 2.4 0.5 0.1 0.3 0.5 1.1 0.9 2.0 0.9 0.5 0.7 0.8 0.6 0.0 0.1 2.8 0.0 0.0 0.0 0.0 3.4 2.3 1.6 1.9 0.0 0.0 0.0 3.5 0.0 0.0 0.3 11.4 0.1 2.3 0.0 2.6 4.5 15.8 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.6 0.0 2.3 0.0 1.3 0.0 0.1 0.0 0.0 0.0 1.4 8.1 8.5 0.0 0.5 0.0 3.4 0.9 0.0 0.7 0.2 2.9 0.0 1.5 0.2 2.9 8.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.8 0.4 0.5 0.5 0.5 0.6 0.5 1.1 0.6 5.3 3.2 1.1 0.0 0.0 0.3 0.4 0.0 1.2 0.0 0.2 0.9 1.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.3 7.4 5.7 4.3 0.0 0.0 0.0 0.0 0.4 5.5 0.0 12.2 0.0 3.8 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 2.3 5.6 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.4 3.1 1.3 0.8 0.1 0.8 0.3 4.5 0.0 0.1 PAGR1 "C16orf53, GAS, MGC4606, PA1" ENSG00000280789 "PAXIP1 associated glutamate rich protein 1" Q9BTK6 16 29816152-29822489 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 166.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Plasma cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041440, HPA043608" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" "HPA041440: AB_10795541, HPA043608: AB_10797144" "unprognostic (2.35e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" "unprognostic (1.44e-2)" "unprognostic (4.20e-1)" "unprognostic (1.14e-3)" "unprognostic (7.09e-3)" "unprognostic (5.12e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (1.84e-3)" "unprognostic (3.41e-2)" "unprognostic (1.51e-2)" "unprognostic (8.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (5.39e-2)" 23.5 27.8 10.2 5.5 10.8 6.5 23.2 18.4 12.3 120.8 8.9 48.9 8.7 55.3 7.1 25.7 68.4 6.1 32.0 10.1 9.9 30.4 28.1 23.0 8.7 10.9 10.7 166.5 26.3 7.4 128.9 3.7 10.8 69.3 5.7 6.8 21.4 8.8 24.6 18.0 30.8 4.7 10.5 23.6 26.4 31.2 10.6 9.3 30.2 9.0 6.8 50.7 73.8 12.5 16.7 24.1 13.9 8.7 7.0 6.7 11.8 12.7 11.5 14.5 12.7 17.1 16.9 33.4 12.7 9.1 7.2 15.4 15.2 19.1 9.2 14.8 31.1 14.8 16.4 16.1 7.3 23.6 26.9 7.5 15.1 10.2 10.0 13.4 12.1 31.0 20.1 10.4 9.9 45.2 18.6 27.6 19.3 14.2 20.4 35.4 24.5 24.9 10.8 7.8 34.9 13.2 9.6 22.4 9.7 10.5 20.9 15.0 9.2 12.0 10.9 15.2 12.9 19.4 21.3 13.1 15.8 24.2 15.0 22.5 16.9 33.0 19.7 17.0 22.1 19.7 16.8 20.0 21.3 19.5 21.7 20.1 11.0 13.9 19.6 21.5 12.7 15.2 10.2 10.8 18.4 12.3 10.1 9.9 10.9 10.7 10.8 10.5 10.6 12.5 1.3 0.0 9.8 66.6 15.2 0.0 0.3 0.1 18.2 3.5 4.7 2.9 0.6 14.3 6.9 1.8 0.0 5.6 5.3 5.9 0.0 27.9 0.5 1.0 1.3 3.8 14.6 10.7 16.2 21.7 8.2 4.4 13.3 0.8 7.6 0.3 6.1 2.0 7.5 5.0 16.5 11.1 0.0 5.6 0.0 0.6 0.9 7.7 0.0 9.4 22.5 1.9 4.1 11.6 8.6 13.5 15.8 3.4 34.5 0.7 20.7 2.1 3.0 3.3 0.0 0.9 5.0 3.1 1.6 16.7 0.4 6.7 10.9 0.2 13.2 0.2 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.9;pancreas: 42.7;pituitary gland: 13.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 104.1;Excitatory neurons: 364.0;Inhibitory neurons: 323.5;Oligodendrocyte precursor cells: 165.9;Peritubular cells: 81.3" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Cell line enhanced" "Detected in some" "EFO-21: 10.8;HAP1: 9.9;HDLM-2: 12.4;NTERA-2: 9.7;SCLC-21H: 12.4;SH-SY5Y: 7.7;U-2197: 7.6;U-251 MG: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 1.0 5.2 16.9 1.6 16.2 0.1 5.2 0.0 17.6 2.3 0.0 0.7 0.2 5.4 5.8 0.7 2.5 1.6 0.3 17.8 31.9 0.7 0.2 0.9 1.7 1.6 0.0 6.2 42.7 0.1 13.7 0.6 6.0 3.4 0.7 7.0 2.2 4.8 1.6 1.3 0.5 4.7 0.4 2.0 2.0 2.6 13.2 0.6 6.2 0.4 0.8 0.9 0.7 2.8 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 0.0 0.0 10.8 1.2 1.6 0.0 9.9 0.6 1.3 12.4 0.4 0.0 1.3 0.0 0.0 0.0 0.4 0.3 0.0 0.1 2.2 5.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 9.7 0.0 2.2 0.1 4.3 0.0 0.8 0.0 12.4 7.7 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.7 4.7 7.6 13.6 0.1 0.1 0.1 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 16.2 0.0 17.6 17.8 31.9 1.6 0.0 6.0 0.4 13.2 2.8 0.9 3.2 1.1 16.0 0.6 0.3 13.3 0.2 0.0 104.1 6.9 10.4 1.0 20.0 0.7 0.0 0.0 0.3 0.2 0.2 0.0 4.7 4.4 1.0 10.8 2.3 3.6 0.0 364.0 13.1 0.4 10.3 10.2 1.7 1.3 21.9 1.4 0.2 0.2 6.7 323.5 0.3 0.0 0.3 5.7 7.0 34.2 1.1 0.0 17.8 0.7 27.5 1.0 165.9 12.0 5.3 0.0 81.3 1.0 1.7 0.0 0.6 0.0 6.0 0.0 1.6 7.8 1.4 1.4 0.3 1.1 6.7 2.4 29.2 0.3 0.9 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PARP12 "ARTD12, FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023749-140062951 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA003584: AB_1079568, HPA063872: AB_2685139" "unprognostic (1.46e-3)" "unprognostic (2.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "unprognostic (6.74e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (2.30e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (7.51e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (4.12e-7)" "unprognostic (3.31e-2)" "unprognostic (2.76e-1)" "unprognostic (1.75e-2)" "unprognostic (6.01e-2)" 6.4 4.7 4.1 12.3 4.3 15.8 6.6 3.6 5.3 4.0 5.2 12.1 18.3 7.6 9.6 4.8 8.1 9.3 5.9 3.6 4.2 5.0 7.8 15.4 13.4 8.3 4.4 6.3 9.2 10.2 2.3 9.9 5.4 7.0 11.6 1.8 17.2 4.8 2.9 15.0 18.1 7.9 6.3 17.1 13.1 10.4 4.9 10.7 5.8 2.5 9.5 8.7 2.4 5.0 20.8 7.6 0.6 0.8 2.4 5.7 15.1 4.7 10.4 36.3 42.5 4.9 12.6 8.6 11.5 3.9 28.0 9.3 5.4 17.6 6.0 33.4 8.7 9.2 4.9 6.8 15.2 2.4 6.2 5.7 6.7 12.7 15.5 9.9 28.2 10.4 19.0 6.0 2.7 8.4 25.7 14.3 1.3 10.7 18.0 15.2 0.0 2.7 7.1 7.9 4.6 0.0 14.2 7.7 11.2 0.7 9.2 5.6 31.0 4.3 10.2 0.3 14.5 0.5 1.5 2.0 7.9 12.2 5.2 1.2 3.0 4.3 1.5 5.5 1.3 1.7 2.1 1.6 2.1 2.4 0.9 0.7 1.0 2.5 6.4 0.2 5.8 1.2 4.1 4.3 3.6 5.3 3.6 4.2 8.3 4.4 5.4 6.3 4.9 5.0 24.1 6.4 10.6 2.6 17.9 6.5 7.2 4.4 8.0 2.9 6.2 5.5 5.4 7.2 5.8 11.0 2.1 6.0 13.0 48.9 1.9 13.9 0.7 7.0 6.4 18.1 24.0 4.8 1.2 26.0 19.1 6.9 18.3 6.3 19.7 38.2 7.9 10.9 24.2 0.0 2.6 19.4 4.1 13.6 9.7 0.9 7.2 20.5 7.2 26.2 17.5 2.9 11.3 9.5 3.1 35.2 37.0 7.2 8.3 12.4 44.2 6.9 9.0 2.5 0.0 7.3 7.9 35.0 15.6 8.7 9.9 2.1 15.6 8.4 11.6 10.6 PARP14 "ARTD8, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 74.7;BJ hTERT+ SV40 Large T+ RasG12V: 113.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 14.0 12.6 4.3 24.3 5.1 20.1 11.3 3.6 2.7 11.4 5.5 11.5 15.3 8.2 2.4 9.0 10.7 15.2 11.1 2.8 5.1 14.9 24.5 33.5 24.0 15.1 5.9 9.2 7.8 7.3 7.6 17.8 8.6 13.0 8.7 1.1 11.7 7.2 5.0 5.3 17.5 10.2 10.9 37.4 11.7 2.2 8.9 15.4 14.7 8.3 26.8 13.7 9.4 7.8 15.6 13.0 8.0 8.3 9.1 26.2 0.0 6.1 40.1 74.7 113.1 6.9 28.7 0.0 24.2 13.4 41.8 11.5 11.9 11.6 15.0 24.0 1.5 14.6 5.8 8.7 20.4 6.4 6.8 14.7 4.7 13.0 4.8 16.4 32.2 12.3 7.0 22.7 2.1 7.9 24.8 1.5 1.1 2.1 11.1 34.2 8.3 4.3 9.5 16.2 0.6 0.0 15.3 3.1 14.1 0.8 5.7 9.3 22.0 4.0 9.4 2.3 5.5 8.7 1.6 2.7 12.0 13.8 7.2 13.1 10.8 5.8 8.6 13.7 7.2 12.8 4.5 5.6 5.6 20.3 3.6 4.1 29.5 9.5 14.7 0.7 9.9 4.3 4.3 5.1 3.6 2.7 2.8 5.1 15.1 5.9 8.6 10.9 8.9 7.8 111.5 246.8 98.4 17.3 115.3 16.8 17.0 35.9 13.1 2.1 19.6 15.6 14.6 24.3 65.9 25.8 4.2 14.1 64.9 43.0 3.9 36.0 0.3 118.8 59.8 94.7 10.7 18.5 0.5 41.2 28.4 37.2 24.5 149.8 32.2 69.6 67.1 32.5 36.5 0.0 3.0 18.2 26.4 61.6 39.9 2.1 28.0 83.9 16.0 124.6 132.2 15.1 58.7 47.3 1.1 44.0 20.2 17.3 50.9 31.8 29.5 11.5 73.0 1.0 13.1 32.7 30.3 1.9 1.1 13.7 10.5 4.8 51.4 42.8 16.0 25.9 PARP9 "ARTD9, BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 95.8;BJ hTERT+ SV40 Large T+ RasG12V: 113.4;SK-MEL-30: 93.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" Mitochondria "HPA066708: AB_2685707" "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 20.1 29.4 14.0 35.8 15.1 20.8 17.6 13.8 17.4 20.3 14.8 22.5 21.2 19.6 19.1 24.8 20.1 28.8 18.3 13.5 15.1 22.0 68.3 36.5 30.5 21.3 15.5 12.9 22.0 23.7 18.5 20.1 16.8 18.9 19.5 5.8 39.9 12.6 13.6 11.6 21.4 29.1 17.6 44.3 20.0 6.4 17.4 30.6 16.8 17.3 25.9 26.0 16.5 16.1 23.1 7.7 2.8 1.9 16.9 34.6 2.6 7.6 41.0 95.8 113.4 12.0 24.9 5.2 16.4 15.3 60.2 24.8 6.6 13.4 19.9 40.3 4.5 24.9 7.6 6.4 18.0 8.1 15.9 28.4 12.9 13.6 3.4 19.1 20.8 15.7 2.3 20.7 3.9 10.2 26.0 10.1 1.1 4.7 21.1 27.3 27.2 1.7 37.0 13.1 1.7 6.6 20.2 3.3 93.8 1.5 10.7 9.0 12.6 4.1 11.8 0.9 4.7 12.8 7.1 9.5 14.1 8.7 7.7 41.9 29.9 36.9 19.8 41.1 18.5 15.9 20.6 22.3 27.5 11.4 15.6 19.3 87.5 30.2 45.2 3.3 24.9 23.3 14.0 15.1 13.8 17.4 13.5 15.1 21.3 15.5 16.8 17.6 17.4 16.1 37.0 41.7 44.2 13.4 18.9 7.1 10.8 13.8 12.5 0.8 10.5 6.3 5.8 10.0 35.1 20.2 0.0 5.2 14.0 32.5 1.9 30.4 1.6 23.6 28.1 37.4 10.7 19.0 0.3 39.9 19.3 19.9 22.4 23.2 10.1 19.5 21.8 50.1 42.0 0.0 1.3 11.5 10.2 32.3 9.2 4.5 18.3 41.2 7.2 45.0 50.2 12.1 32.0 17.1 3.9 36.8 11.7 24.0 13.6 8.9 17.5 19.3 48.8 1.0 19.7 18.9 16.3 0.9 1.9 15.7 6.7 1.6 23.5 17.0 8.6 14.4 PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 56.9;dendritic cells: 51.7;granulocytes: 60.1;Hofbauer cells: 66.7;Kupffer cells: 87.3;Langerhans cells: 53.4;Macrophages: 91.9;monocytes: 62.0;T-cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HL-60: 116.4;NB-4: 44.9;THP-1: 64.7;U-937: 53.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" 3.5 2.9 3.7 26.7 3.5 49.7 1.8 4.4 7.1 2.6 4.0 3.1 3.6 2.4 0.6 2.5 2.2 6.2 1.3 3.8 4.7 1.8 3.1 10.4 30.1 8.2 4.9 0.8 1.4 0.5 1.3 3.0 6.9 2.1 3.4 0.2 2.6 1.1 1.2 1.7 12.7 2.9 5.9 28.9 4.4 1.7 7.9 18.4 1.9 0.4 26.8 4.7 1.5 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 116.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 16.8 44.9 0.1 0.0 0.0 9.2 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 64.7 0.0 0.0 11.5 0.2 0.0 0.3 0.0 0.3 0.0 53.9 1.9 12.5 62.0 71.3 13.9 57.6 13.9 21.4 8.0 15.2 49.2 20.4 8.9 10.3 72.2 13.1 65.9 33.3 12.1 44.6 3.7 3.5 4.4 7.1 3.8 4.7 8.2 4.9 6.9 5.9 7.9 9.4 1.3 6.4 14.0 1.0 56.9 2.4 0.1 0.0 0.6 0.2 0.7 1.5 1.1 0.0 3.1 0.0 0.0 0.6 51.7 0.1 0.0 0.0 4.2 3.7 0.4 2.9 0.0 10.1 3.9 0.2 0.7 2.3 3.6 2.5 60.1 0.0 3.9 1.3 66.7 0.0 2.9 0.0 0.0 87.3 53.4 2.7 0.0 91.9 5.4 10.3 62.0 0.0 26.8 0.0 1.4 0.0 0.0 0.0 15.9 0.0 0.0 0.5 1.5 0.2 0.0 0.5 0.4 1.1 0.8 0.4 1.8 1.0 48.3 0.0 0.1 0.1 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH19 "EFMR, EIEE9, KIAA1313" ENSG00000165194 "Protocadherin 19" Q8TAB3 X 100291644-100410273 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 21.5" "Cell type enhanced" "Detected in many" "Adipocytes: 29.9;Excitatory neurons: 24.5;Inhibitory neurons: 51.8;Oligodendrocyte precursor cells: 40.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6;ovarian cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027533 Approved Approved Cytosol NA NA 83000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027533: AB_10602043" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (5.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (4.77e-2)" "unprognostic (3.64e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-1)" "unprognostic (2.79e-1)" "unprognostic (9.77e-3)" "unprognostic (2.82e-3)" "unprognostic (1.53e-1)" "unprognostic (1.80e-4)" "unprognostic (1.37e-1)" 1.8 0.1 6.8 0.2 7.6 0.0 1.7 0.0 10.7 1.6 0.0 1.3 0.2 1.1 0.2 0.8 0.6 0.4 0.3 10.7 12.0 0.2 0.0 0.1 0.2 0.6 1.3 1.0 0.1 0.1 0.7 0.1 4.1 0.2 1.7 1.8 0.6 0.3 0.4 0.9 0.4 0.9 0.0 0.0 0.5 0.6 21.5 0.8 0.2 0.9 0.0 0.8 0.6 0.0 0.0 0.0 18.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 3.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.6 0.0 10.7 10.7 12.0 0.6 1.3 4.1 0.0 21.5 0.0 29.9 0.0 0.5 13.4 0.0 3.1 0.1 0.9 4.6 12.9 0.5 0.8 1.8 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.4 6.2 11.3 1.8 0.0 24.5 0.0 0.1 2.9 0.0 1.4 0.0 2.5 1.1 0.0 0.1 0.0 51.8 0.1 0.0 0.3 3.4 2.2 3.4 0.1 0.0 7.5 0.0 1.9 0.0 40.7 2.2 0.1 0.1 0.4 0.0 0.4 0.0 0.2 1.3 1.9 0.0 5.9 7.8 0.1 1.5 1.0 1.6 0.0 0.2 0.7 0.0 0.1 PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720415-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Group enriched" "Detected in many" 8 "Astrocytes: 311.8;Excitatory neurons: 1152.0;Inhibitory neurons: 882.3;Oligodendrocyte precursor cells: 917.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 43.4;RH-30: 120.4;RT4: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" 1.8 3.2 10.5 5.2 14.6 0.0 3.0 0.0 33.7 23.9 0.0 19.2 3.2 16.9 25.1 14.3 9.7 8.1 19.1 23.7 50.1 2.0 1.0 2.9 1.4 13.0 14.3 4.7 0.9 1.1 0.2 0.2 14.3 10.6 7.8 3.4 0.8 18.2 0.6 11.6 5.0 22.1 3.9 18.6 11.4 1.0 46.3 1.4 4.1 0.4 1.2 16.3 5.9 11.8 0.0 1.1 14.4 20.1 29.5 28.5 0.0 3.8 0.0 1.9 0.9 1.9 26.5 0.0 0.1 0.2 0.0 15.3 1.3 38.5 3.4 0.0 43.4 0.1 26.8 0.0 30.4 0.6 0.0 17.2 8.8 1.0 10.7 17.5 7.5 0.0 0.0 0.0 9.0 0.1 0.0 0.1 8.8 9.3 4.0 0.0 120.4 0.0 0.9 65.2 0.9 0.2 0.4 1.2 1.3 8.2 1.8 6.9 0.0 24.1 6.2 6.7 0.0 0.0 0.0 0.0 18.8 0.1 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 14.6 0.0 33.7 23.7 50.1 13.0 14.3 14.3 3.9 46.3 11.8 1.1 0.0 0.0 311.8 0.3 85.0 92.4 25.7 46.7 46.8 0.7 9.0 83.2 0.0 13.7 64.4 0.0 0.1 0.0 0.3 0.0 0.6 16.9 66.8 8.4 7.6 0.0 0.0 1152.0 0.7 0.1 24.0 20.9 60.4 1.3 0.8 19.2 0.1 0.3 10.1 882.3 0.5 4.1 1.0 3.5 10.4 0.3 1.3 21.4 43.1 0.0 1.3 0.0 917.3 26.4 26.5 0.0 28.6 1.3 26.1 0.0 0.2 27.0 3.4 0.0 51.3 11.0 1.1 2.7 18.5 38.6 0.1 1.8 1.7 0.3 50.3 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 599.4;Hepatocytes: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 313.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" NA NA 510000000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 78.5 33.5 15.4 12.7 15.7 3.7 34.4 12.1 18.4 56.5 29.3 26.9 24.9 39.9 33.6 38.8 35.6 31.7 37.7 14.7 27.8 92.6 103.5 56.2 14.6 16.5 22.0 39.6 20.6 66.0 17.9 29.0 24.9 44.3 23.6 30.7 70.1 46.6 92.1 33.0 24.5 40.8 14.6 15.6 22.1 14.2 28.4 11.1 60.0 50.4 14.2 25.7 25.2 13.2 38.8 54.9 43.2 48.6 313.2 160.0 37.9 64.8 59.4 35.4 26.5 86.5 33.6 4.0 27.3 89.2 58.2 62.2 31.7 50.2 40.5 22.1 26.9 14.9 41.0 75.7 31.4 14.1 12.7 154.9 54.1 47.4 13.3 93.9 42.6 14.2 27.0 27.8 50.7 23.6 10.7 22.8 26.1 55.9 23.1 19.6 90.2 34.5 50.1 42.8 11.3 24.1 97.8 47.7 45.5 61.0 39.1 18.2 53.4 59.2 32.7 52.9 34.2 22.9 55.1 5.1 71.3 19.3 22.1 16.3 6.5 6.8 8.3 5.4 10.4 3.7 8.0 6.7 5.9 2.8 10.8 9.2 4.1 6.1 6.0 7.4 7.8 6.5 15.4 15.7 12.1 18.4 14.7 27.8 16.5 22.0 24.9 14.6 28.4 13.2 37.3 599.4 77.5 16.0 12.2 21.3 23.1 43.9 29.6 48.7 46.0 31.8 81.1 40.0 49.9 53.3 43.8 43.4 12.1 30.7 7.9 26.7 1.7 18.4 65.9 33.4 8.5 12.0 24.7 10.2 36.0 81.9 22.4 36.2 10.1 20.9 39.7 187.8 22.1 57.2 36.8 21.0 36.7 17.4 9.2 3.9 89.2 14.3 24.9 23.4 8.6 90.3 11.3 21.6 18.0 13.9 21.0 120.7 26.2 27.0 47.7 69.0 25.0 36.9 72.3 65.5 63.7 14.7 32.2 40.8 28.3 22.0 14.5 56.2 26.5 18.4 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 702.6;Rod photoreceptor cells: 272.3;Syncytiotrophoblasts: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 289.6;ASC TERT1: 233.8;K-562: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" 32.9 16.9 103.0 20.9 82.9 15.8 22.3 142.7 106.1 28.0 32.4 22.5 24.2 17.4 73.5 37.9 19.8 19.5 729.5 115.5 118.5 42.0 63.5 36.1 21.7 102.2 95.6 8.6 21.4 84.6 53.1 68.5 109.7 29.2 25.4 173.3 34.9 22.9 2164.0 26.1 29.4 18.8 96.8 17.2 29.7 9.2 139.9 12.1 16.9 1379.7 23.2 24.0 17.1 114.9 39.2 7.5 10.6 11.6 289.6 233.8 60.7 45.2 42.3 42.7 55.7 35.5 24.1 19.8 13.7 64.5 121.3 19.8 25.7 31.5 72.1 14.7 36.8 10.0 16.2 14.2 76.2 8.8 10.2 167.5 61.9 181.7 97.8 96.9 17.1 16.3 222.1 45.0 76.8 66.2 6.9 5.4 37.1 32.3 15.9 14.6 26.5 7.7 25.4 39.9 50.1 4.7 44.1 123.4 36.1 44.7 37.5 11.7 22.9 49.3 11.2 124.7 100.9 19.9 29.6 29.1 200.6 8.0 30.2 10.6 5.7 4.5 5.3 6.1 5.5 12.0 10.6 7.1 7.0 11.0 8.1 4.5 1.3 4.9 2.1 3.0 14.4 4.8 103.0 82.9 142.7 106.1 115.5 118.5 102.2 95.6 109.7 96.8 139.9 114.9 5.7 51.3 45.1 81.3 24.0 28.8 9.9 19.8 23.3 71.0 16.1 11.3 702.6 24.3 45.4 69.9 114.7 184.6 9.5 24.0 62.6 13.1 38.9 41.1 14.2 15.7 43.2 7.4 85.8 7.1 148.3 54.2 20.4 27.0 13.9 6.1 5.3 80.8 45.0 33.7 81.1 32.0 20.3 46.1 90.4 50.0 10.5 68.7 55.2 6.5 21.5 45.7 14.4 65.9 41.5 4.5 25.1 9.8 37.5 4.1 48.8 20.7 88.0 272.3 32.9 131.2 40.1 8.7 15.9 14.6 16.3 309.2 24.0 4.2 24.2 4.3 PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 968.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 89.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA007722: AB_1855130" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (8.99e-3)" "unprognostic (2.75e-2)" "unprognostic (3.42e-1)" "unprognostic (3.72e-1)" "unprognostic (4.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.94e-2)" 16.7 16.6 20.9 8.5 32.3 3.3 10.5 21.9 22.4 11.6 15.2 24.0 15.3 9.1 7.3 6.4 9.0 15.8 8.0 17.3 20.1 24.3 30.0 10.8 5.6 23.8 28.5 12.7 14.5 16.9 6.7 11.4 23.6 6.9 21.9 14.5 6.4 9.6 5.8 6.3 13.6 10.6 19.5 6.3 11.0 11.0 26.9 4.6 12.3 6.5 5.1 17.7 7.0 45.2 29.0 48.4 7.9 5.4 32.7 17.2 9.6 19.4 21.1 16.6 18.9 10.9 16.9 5.8 14.6 25.9 19.7 20.2 33.8 14.9 22.0 10.8 20.2 7.7 30.3 15.6 23.5 4.5 11.3 17.4 9.1 19.6 18.6 14.3 21.6 6.4 15.6 18.3 15.2 24.5 2.6 4.5 3.8 9.5 8.6 3.6 6.5 8.1 13.2 89.0 18.3 14.1 18.9 20.3 55.5 8.7 6.7 8.7 17.1 38.4 13.6 13.9 31.6 8.9 16.7 6.2 26.1 18.1 11.0 0.0 0.9 0.6 0.3 0.7 0.6 0.2 0.5 0.6 0.5 0.3 0.7 0.3 0.0 0.2 1.6 0.0 1.1 0.2 20.9 32.3 21.9 22.4 17.3 20.1 23.8 28.5 23.6 19.5 26.9 45.2 30.7 6.4 26.5 83.9 14.8 11.3 11.1 13.9 18.2 13.0 6.6 5.2 6.8 41.5 15.4 7.3 12.5 8.0 5.5 58.7 7.9 11.3 6.4 12.5 21.6 24.3 14.5 0.8 60.8 9.6 7.1 16.2 26.5 20.6 22.1 17.9 14.3 23.3 10.8 10.1 126.2 19.0 4.1 12.3 18.9 5.6 10.8 19.2 10.6 85.3 9.0 2.6 10.3 119.1 968.6 11.5 31.8 11.3 7.2 25.4 22.1 21.1 10.5 31.2 39.5 17.8 24.5 25.6 17.3 7.5 10.4 4.5 10.8 25.3 28.5 26.4 PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 106.5;ovary: 78.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;dendritic cells: 30.0;Ductal cells: 30.6;Fibroblasts: 44.3;Inhibitory neurons: 95.0;Microglial cells: 28.1;NK-cells: 46.4" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Group enriched" "Detected in many" 6 "ASC diff: 139.8;HHSteC: 42.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.4" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 95000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" 20.4 106.5 0.5 3.4 0.8 0.9 21.7 0.7 1.3 25.1 9.0 8.8 4.1 11.8 7.1 1.9 9.3 34.0 23.2 0.8 2.2 7.7 2.3 3.1 7.4 5.1 6.6 78.0 25.7 17.1 13.4 7.0 9.4 10.0 9.8 1.5 8.6 37.4 2.2 7.9 4.8 9.7 1.8 2.8 23.4 3.3 2.0 3.7 18.3 8.8 5.4 15.8 15.4 2.3 0.0 7.8 4.0 0.0 139.8 4.2 0.1 0.9 0.8 0.7 0.8 0.0 1.3 7.4 1.4 7.3 5.2 0.4 0.0 0.2 0.3 0.0 3.2 0.2 1.6 0.3 42.6 0.0 0.1 14.7 0.0 0.1 0.0 0.2 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 1.4 0.0 2.1 0.0 6.7 0.0 0.1 9.6 0.0 13.8 3.2 1.8 0.0 2.0 1.0 0.1 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 9.5 16.4 0.0 1.4 0.4 1.7 7.2 0.0 0.0 0.2 6.0 0.2 17.1 0.1 0.0 0.1 4.2 0.5 0.8 0.7 1.3 0.8 2.2 5.1 6.6 9.4 1.8 2.0 2.3 15.6 0.0 0.0 1.0 1.6 3.1 7.7 0.2 1.8 2.3 1.7 9.4 4.5 32.9 0.6 5.5 0.0 0.2 30.0 0.2 0.0 30.6 8.2 0.8 1.8 10.3 1.8 1.3 13.9 4.4 0.2 44.3 0.0 1.4 0.0 8.1 2.9 0.0 0.3 26.9 95.0 1.0 0.0 1.3 3.7 13.3 0.3 0.8 0.0 28.1 0.9 1.5 46.4 2.0 2.8 3.0 0.5 2.2 8.4 1.6 0.0 0.3 0.0 0.5 6.6 1.9 3.7 0.4 4.3 0.3 2.0 0.0 10.2 5.2 0.6 3.2 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDLIM4 RIL ENSG00000131435 "PDZ and LIM domain 4" P50479 5 132257696-132273454 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 315.5;Prostatic glandular cells: 473.0;Skeletal myocytes: 225.2;Urothelial cells: 381.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 91.8;HBEC3-KT: 109.2;HHSteC: 103.7;hTEC/SVTERT24-B: 117.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011912 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Cytosol" "HPA011912: AB_1856277" "unprognostic (1.36e-3)" "unprognostic (1.93e-1)" "unprognostic (1.62e-2)" "unprognostic (8.08e-3)" "unprognostic (4.70e-3)" "unprognostic (2.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-2)" "unprognostic (4.20e-2)" "unprognostic (5.84e-3)" "unprognostic (1.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.57e-2)" "unprognostic (3.40e-3)" 24.8 6.6 14.5 18.6 13.8 0.7 34.5 17.9 17.8 36.5 20.1 104.9 6.9 90.7 17.7 50.0 48.3 20.5 61.6 15.8 23.8 33.3 1.2 10.5 4.5 27.7 20.5 28.4 6.5 4.9 28.2 8.0 21.3 50.2 4.8 2.6 47.4 28.1 5.4 64.4 27.2 42.9 22.5 6.7 32.2 6.3 17.9 6.6 14.2 2.6 10.1 59.4 39.1 21.7 46.6 0.0 9.7 0.1 13.2 36.7 3.3 12.9 6.3 12.9 4.2 0.0 4.3 0.3 8.6 68.4 65.8 91.8 0.0 109.2 6.1 0.2 5.1 0.0 0.0 2.2 103.7 0.0 0.3 46.5 7.8 117.6 43.7 45.9 74.0 0.0 20.2 0.1 57.6 0.0 0.0 0.3 3.4 0.0 28.1 2.2 66.4 0.2 29.0 0.0 0.0 39.0 29.7 0.0 0.0 7.7 0.1 4.8 47.9 46.3 49.9 48.4 72.9 0.1 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.5 13.8 17.9 17.8 15.8 23.8 27.7 20.5 21.3 22.5 17.9 21.7 10.1 0.0 4.4 5.5 0.7 105.7 315.5 183.8 76.2 0.5 38.2 149.5 6.8 0.0 57.0 14.7 2.1 5.1 0.8 0.6 107.6 121.5 14.2 21.1 81.0 69.8 16.8 0.0 0.7 9.9 14.4 85.1 6.1 17.9 4.5 10.7 21.0 0.3 6.6 0.0 0.6 16.6 61.1 0.3 32.5 15.8 36.4 3.4 165.4 3.7 1.0 17.7 0.0 0.0 0.3 105.7 154.6 27.4 0.0 473.0 5.6 8.9 138.3 0.7 26.3 225.2 53.8 9.9 13.9 47.8 82.8 22.8 4.2 2.0 5.5 381.7 PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 629.5;skeletal muscle: 1163.5;tongue: 576.0" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 1844.2" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 219.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 219.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" 41.7 26.0 20.5 25.6 25.2 59.7 39.5 22.4 22.4 27.4 84.9 34.1 33.3 94.8 11.3 72.3 40.5 47.5 629.5 21.4 27.7 34.9 82.7 22.0 16.2 30.9 30.1 27.2 30.2 12.2 17.5 67.7 25.0 88.5 30.8 18.2 40.2 68.9 1163.5 21.5 34.4 105.9 22.7 24.1 31.0 12.7 26.3 10.9 25.5 576.0 21.1 45.8 27.6 21.0 31.4 87.2 33.6 13.0 71.7 51.3 13.0 71.6 59.9 40.1 32.6 80.8 66.3 12.0 72.0 72.3 21.0 31.8 46.5 68.2 65.9 24.1 19.3 43.7 53.8 32.2 103.7 14.6 38.3 66.4 58.4 96.1 74.0 177.9 93.5 13.2 19.2 12.5 86.2 29.8 15.0 4.8 11.4 66.7 36.6 7.2 24.7 11.1 45.0 94.6 16.5 21.8 38.9 88.7 20.3 26.7 10.3 5.2 113.7 103.7 17.3 46.1 44.1 9.5 13.0 12.7 56.5 10.3 24.9 219.7 23.4 21.0 12.1 40.6 9.7 10.5 12.0 12.8 19.5 7.6 7.9 10.4 22.6 9.2 44.6 6.6 11.8 15.2 20.5 25.2 22.4 22.4 21.4 27.7 30.9 30.1 25.0 22.7 26.3 21.0 107.4 44.8 23.6 184.1 22.1 194.4 380.3 92.1 63.7 4.7 90.2 67.4 1844.2 62.9 82.9 49.7 31.3 13.7 18.5 180.0 13.7 95.0 19.2 68.7 11.8 117.2 109.4 27.6 4.9 95.1 96.5 97.8 84.6 108.7 52.0 29.1 137.8 207.0 38.8 1.7 20.7 107.4 36.7 60.6 75.3 9.1 41.3 59.8 62.2 104.0 41.6 86.2 12.3 181.5 43.1 139.2 166.8 66.5 23.2 300.7 117.5 73.6 70.0 35.8 78.9 96.7 134.7 23.8 34.4 107.3 157.0 23.8 31.1 6.8 74.0 217.5 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.1;Plasma cells: 318.8;Squamous epithelial cells: 208.0;Suprabasal keratinocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Cell line enhanced" "Detected in many" "CACO-2: 58.8;U-698: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 27.6 7.9 10.2 28.1 14.4 228.5 25.7 11.9 13.5 17.9 9.2 18.6 17.6 17.3 8.6 42.9 12.7 26.1 11.8 13.8 11.2 10.6 13.5 31.0 24.7 12.2 11.2 5.5 9.3 37.9 15.8 15.6 12.2 8.9 20.1 5.1 18.9 7.7 7.1 29.7 23.2 13.9 12.6 21.8 18.1 10.7 10.9 28.3 9.7 10.0 29.0 22.4 23.7 15.6 3.6 2.8 36.5 24.6 4.2 3.2 8.3 4.8 5.4 4.3 6.8 58.8 4.1 48.3 11.3 1.7 1.6 5.8 11.1 10.5 8.6 12.2 8.9 4.4 1.7 9.5 12.4 4.8 8.3 4.2 8.1 6.4 21.6 4.5 24.3 18.2 2.7 11.7 3.7 0.3 10.6 6.9 23.8 11.1 1.7 13.2 12.6 28.1 17.7 10.8 16.7 23.3 3.6 5.5 12.9 11.3 3.0 3.3 17.5 4.0 5.7 4.0 7.1 27.0 2.8 146.7 2.1 4.3 10.9 15.0 15.6 15.0 0.9 14.1 1.7 8.5 4.8 1.9 5.4 6.6 5.6 2.5 76.9 3.0 23.2 0.5 11.6 6.6 10.2 14.4 11.9 13.5 13.8 11.2 12.2 11.2 12.2 12.6 10.9 15.6 94.5 28.9 49.2 4.6 84.4 224.1 74.6 48.2 105.9 1.7 60.9 50.3 5.7 15.7 52.0 5.5 0.0 1.7 16.9 57.9 1.9 5.3 10.6 34.6 26.4 52.1 25.7 3.4 23.4 26.7 8.6 24.5 75.4 58.7 15.2 6.3 37.5 7.5 22.8 3.3 19.1 23.4 30.5 67.6 103.7 11.2 1.5 107.0 112.1 119.9 30.6 5.5 3.1 82.9 67.9 20.9 45.9 1.9 318.8 44.7 32.7 9.6 43.6 2.0 0.0 10.1 51.9 8.4 9.6 208.0 217.5 4.0 49.4 3.2 32.4 145.8 PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 5241.0;monocytes: 4824.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" 573.1 365.8 278.0 1133.4 302.0 1613.0 397.0 323.2 333.0 393.7 289.2 970.2 764.0 734.4 346.4 582.7 500.9 372.7 343.8 281.8 301.5 460.9 661.6 559.2 1357.9 347.3 325.4 247.7 246.4 311.3 198.9 581.1 348.6 419.4 808.4 71.8 346.9 601.4 337.9 449.8 772.9 1034.7 315.2 910.8 675.1 116.2 366.2 1197.6 269.2 238.7 1440.0 842.6 425.0 355.2 3019.5 4276.8 1461.5 1205.2 778.8 977.1 1972.7 2416.8 1970.4 2568.6 1923.7 1684.1 1181.1 2476.9 1892.0 2542.0 1453.6 1825.4 1383.6 3040.5 2049.6 3560.1 2355.1 2516.6 2034.3 2225.8 2144.0 1630.4 5006.0 1152.4 1331.9 1957.6 1939.8 1477.6 2361.3 1646.4 1488.6 1736.7 3150.5 1815.0 2469.9 3448.0 2095.2 1474.7 2297.3 2451.9 2035.1 1494.6 2491.7 1909.8 564.0 1586.2 1910.5 1180.9 1679.7 1226.8 1121.0 1359.7 2731.7 2136.6 1675.1 1512.3 3969.3 931.3 1070.7 1799.3 1834.4 1949.7 3316.4 8100.1 8206.3 13914.4 9850.0 10858.8 6780.3 5722.0 8185.7 9586.6 9920.0 4970.0 5238.0 7604.7 9387.0 9112.1 13547.4 7809.7 11245.6 23570.1 278.0 302.0 323.2 333.0 281.8 301.5 347.3 325.4 348.6 315.2 366.2 355.2 561.8 112.2 176.1 12.1 1070.6 1806.0 873.2 3658.3 1003.3 25.0 767.4 914.1 147.6 457.5 1020.0 741.2 0.0 1911.0 1725.6 1733.8 992.0 1866.6 19.7 313.4 546.1 806.6 603.7 713.5 7.1 1625.2 5241.0 599.9 733.4 422.7 486.5 291.2 637.5 754.3 4094.2 38.7 6.4 1399.7 1452.6 1434.3 2934.8 31.0 263.8 1854.7 873.4 21.5 4824.7 99.8 3216.3 9.0 37.2 2933.5 1585.7 375.0 927.8 1238.2 1472.2 1671.2 559.4 17.8 506.2 282.3 1838.4 97.4 355.4 1170.1 1513.5 1682.8 1804.7 410.7 1355.5 1177.9 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavorable (8.78e-4)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 23.6 21.0 12.0 18.1 12.9 9.3 18.0 20.2 15.2 24.4 19.6 18.0 15.8 17.1 34.5 12.3 13.4 24.6 14.3 9.7 10.5 13.6 38.3 16.8 11.2 10.9 10.2 22.7 46.1 13.3 28.2 47.5 13.1 51.0 23.4 26.8 35.8 20.3 6.7 10.9 18.2 18.5 6.6 11.5 24.9 32.3 11.1 8.2 25.6 8.6 15.2 19.0 12.3 15.9 35.1 23.4 41.8 51.0 68.9 72.9 48.9 118.1 82.9 55.2 83.3 60.1 16.1 18.3 24.7 112.3 53.0 20.1 38.4 49.5 104.6 14.6 37.8 22.7 41.9 105.0 77.6 22.6 11.2 46.2 40.1 96.6 120.0 55.5 64.6 12.1 74.9 19.6 61.0 39.1 3.7 14.7 18.8 31.8 31.6 16.2 92.5 11.3 42.0 36.0 16.9 26.3 34.8 28.5 20.9 61.8 27.0 25.5 94.2 38.3 21.2 74.9 60.5 36.5 16.1 13.0 29.7 17.7 58.4 10.8 4.1 2.7 2.6 3.5 3.9 4.6 2.8 3.4 3.6 2.5 4.5 4.7 1.8 3.5 4.5 4.2 2.1 2.3 12.0 12.9 20.2 15.2 9.7 10.5 10.9 10.2 13.1 6.6 11.1 15.9 14.3 28.9 27.7 14.4 13.0 15.8 29.2 28.5 5.7 16.4 19.9 15.0 6.8 15.7 36.1 11.0 10.4 32.4 12.7 15.9 7.9 31.7 67.7 17.0 35.1 13.8 16.1 6.9 25.1 49.6 71.1 46.1 23.9 36.4 5.1 25.4 14.3 32.6 17.6 8.4 29.4 35.5 18.3 6.0 8.7 20.9 33.5 8.6 10.6 15.9 10.1 25.9 2.1 41.2 36.8 37.9 19.7 18.4 44.1 56.5 16.1 23.2 22.2 21.1 6.6 22.1 26.6 75.5 34.2 11.6 15.6 64.4 10.1 12.2 17.6 25.6 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Vesicles, Cytosol" "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.5 13.7 16.3 12.3 25.9 9.4 15.9 22.5 14.6 16.1 17.4 13.2 14.9 18.0 15.7 15.4 14.5 19.0 12.4 10.5 14.0 23.5 15.5 16.6 11.3 16.6 16.1 14.1 12.3 43.6 10.3 23.1 17.0 16.4 13.0 22.4 11.8 14.8 6.4 12.3 11.8 18.3 13.8 13.0 18.0 19.3 19.6 9.4 30.7 12.1 10.9 14.9 12.0 15.8 53.8 24.1 39.6 24.8 28.0 28.3 35.3 33.2 35.7 23.9 33.2 58.9 6.0 15.6 16.2 28.6 39.1 34.8 31.9 25.4 42.1 13.5 27.6 9.8 28.4 23.3 30.6 12.3 14.9 22.2 17.5 23.6 45.8 22.2 57.7 9.9 23.4 14.7 18.6 16.6 6.6 7.7 22.6 30.1 18.5 6.9 41.1 11.0 29.6 47.0 23.2 20.5 50.6 21.4 23.2 33.0 12.7 12.3 72.5 19.1 27.4 50.1 20.4 5.9 14.1 12.8 22.8 11.3 22.6 1.7 1.5 1.1 1.7 1.0 1.1 1.4 1.3 1.3 2.1 1.5 1.7 1.0 2.3 1.8 3.2 1.4 0.9 0.6 16.3 25.9 22.5 14.6 10.5 14.0 16.6 16.1 17.0 13.8 19.6 15.8 93.2 76.9 62.0 217.4 25.0 35.3 26.1 18.7 24.5 49.1 34.7 25.0 29.7 25.8 33.1 36.8 70.9 29.6 29.5 22.6 19.6 19.8 35.9 51.8 35.1 87.6 28.7 11.2 57.0 25.1 17.9 28.6 45.3 72.4 32.2 22.8 106.7 32.4 19.2 35.3 81.1 23.5 18.3 46.3 33.1 18.6 25.7 27.0 19.6 69.3 19.6 73.0 17.5 62.8 79.4 26.1 13.1 31.2 29.9 42.7 15.2 22.4 26.4 40.4 39.5 33.7 35.1 52.6 26.8 23.5 34.0 143.5 25.3 25.1 20.7 37.3 PIP4K2B "PIP5K2B, PIP5KIIB, PIP5KIIbeta" ENSG00000276293 "Phosphatidylinositol-5-phosphate 4-kinase type 2 beta" P78356 17 38765691-38800126 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062220 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA062220: AB_2684715" "unprognostic (7.77e-2)" "unprognostic (8.37e-2)" "unprognostic (3.74e-2)" "unprognostic (1.13e-1)" "unprognostic (2.67e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.64e-1)" "unprognostic (2.33e-1)" "unprognostic (1.50e-2)" "unprognostic (6.10e-3)" "unprognostic (3.79e-1)" "unprognostic (4.82e-3)" "unprognostic (3.38e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.36e-4)" "unprognostic (2.48e-1)" 19.9 27.0 82.5 15.5 85.6 7.3 20.8 62.3 93.9 30.1 43.3 24.2 10.3 28.8 23.3 15.4 29.1 16.3 30.2 90.7 75.2 20.1 14.4 21.4 20.5 65.9 65.7 49.8 16.4 16.6 25.2 22.8 67.1 22.2 14.0 36.0 16.9 25.3 99.0 24.6 17.3 29.5 63.2 23.2 16.4 13.0 80.4 23.4 20.3 75.6 20.4 22.9 20.9 81.4 18.1 40.2 66.0 69.9 56.7 45.5 12.2 31.6 38.2 43.1 35.0 28.2 18.4 44.8 17.2 59.8 36.3 35.9 44.9 28.7 41.4 27.8 17.2 38.4 27.3 40.7 26.2 43.7 23.5 40.0 34.2 33.7 24.2 59.2 36.3 48.6 34.2 22.3 46.8 14.2 44.0 34.0 32.0 20.7 15.8 44.6 63.7 25.6 31.3 22.3 34.0 46.1 30.9 13.9 34.5 68.5 43.6 44.5 33.4 35.8 21.6 29.4 28.9 27.4 36.5 19.7 42.0 36.8 32.9 1.3 1.9 0.6 3.4 1.6 3.5 2.3 2.9 3.3 2.4 2.3 3.2 2.9 1.8 2.8 1.4 2.2 3.0 3.3 82.5 85.6 62.3 93.9 90.7 75.2 65.9 65.7 67.1 63.2 80.4 81.4 15.8 19.2 11.4 21.5 6.7 6.1 3.5 4.6 7.4 31.6 11.5 13.3 23.4 4.3 7.5 5.5 10.4 7.0 14.8 3.7 1.9 5.3 9.2 10.8 17.7 17.3 11.5 9.0 33.5 4.9 5.0 13.8 5.6 9.0 1.3 22.6 18.2 12.7 8.8 43.7 29.1 7.4 2.0 11.3 4.9 21.1 15.2 8.6 1.8 18.7 6.9 14.8 10.3 22.1 24.0 6.0 4.1 16.6 6.2 4.9 5.4 7.7 6.4 14.0 6.6 13.8 13.2 4.6 7.4 9.9 4.4 2.5 8.1 17.3 7.2 2.7 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 252.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.6;Leydig cells: 138.5;Theca cells: 205.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 99.0;RH-30: 94.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: AB_2682893" "unprognostic (4.74e-3)" "unprognostic (8.35e-3)" "unprognostic (5.43e-2)" "unprognostic (1.74e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.32e-2)" "unprognostic (6.17e-2)" "unprognostic (3.49e-2)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.94e-6)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.69e-2)" "unprognostic (5.17e-3)" "unprognostic (4.93e-3)" 37.7 74.8 4.1 18.5 5.2 21.7 29.6 1.9 7.0 31.4 5.8 28.8 9.6 29.5 9.0 32.9 20.8 26.9 26.4 3.8 2.9 17.0 3.6 26.7 12.1 3.6 4.1 36.5 27.7 9.5 81.6 252.3 3.9 26.0 21.3 1.6 30.1 12.1 12.2 61.9 20.6 19.7 3.2 15.6 26.9 8.7 6.0 6.6 13.8 22.3 12.1 39.6 34.4 4.0 0.2 5.0 99.0 0.1 39.4 78.0 0.3 32.9 21.6 16.1 33.5 0.3 6.0 2.7 16.0 30.4 4.0 0.0 0.8 12.0 32.2 3.1 4.4 45.2 58.7 0.9 13.9 40.9 8.9 60.5 4.6 15.8 13.8 23.4 33.5 16.1 4.4 0.8 18.0 6.2 16.9 19.8 17.2 0.0 3.7 20.7 94.1 0.1 33.1 1.1 8.7 10.3 51.0 0.1 0.1 29.6 0.1 50.1 19.8 0.2 35.2 77.7 36.4 9.1 9.0 0.6 25.3 16.6 2.0 4.9 12.0 25.1 1.4 9.1 1.4 3.7 1.3 1.9 14.9 5.8 0.9 1.5 21.7 2.2 2.9 6.7 2.0 3.8 4.1 5.2 1.9 7.0 3.8 2.9 3.6 4.1 3.9 3.2 6.0 4.0 19.5 51.3 51.0 28.4 15.2 21.7 14.6 5.3 34.1 2.1 16.8 14.0 8.4 5.7 12.6 5.5 0.0 4.6 19.0 16.1 7.9 11.8 1.8 8.6 91.9 23.8 16.7 19.3 60.3 11.3 15.0 143.6 11.7 13.0 18.4 38.7 8.6 0.2 20.3 8.4 76.6 33.6 18.3 26.8 27.8 5.5 138.5 26.8 8.8 49.6 37.6 0.9 2.1 10.6 5.5 13.0 22.5 97.0 5.7 52.0 4.3 15.3 4.4 0.4 13.1 61.7 31.1 0.9 1.0 24.1 43.3 9.9 10.0 205.8 28.5 19.7 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.3;tongue: 40.8" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2062.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.7;K-562: 15.6;Karpas-707: 10.7;MOLT-4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031849: AB_10602192" "unprognostic (7.77e-3)" "unprognostic (2.57e-1)" "unprognostic (2.09e-1)" "unprognostic (5.18e-3)" "unprognostic (4.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.05e-1)" "unprognostic (4.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-2)" "unprognostic (7.42e-2)" "prognostic favorable (3.91e-7)" "unprognostic (1.07e-4)" "unprognostic (6.74e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" 4.0 4.1 15.6 2.7 40.5 1.6 2.4 32.5 21.4 4.5 9.5 4.0 0.6 14.8 3.1 3.6 3.3 3.0 32.4 13.8 30.8 31.5 0.5 3.2 3.4 42.6 37.4 7.0 1.6 14.8 2.1 7.9 39.2 10.5 1.3 4.0 2.3 7.1 30.8 0.9 1.8 6.0 22.6 1.9 2.2 1.7 27.7 17.2 3.3 40.8 2.6 4.1 1.9 65.3 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.5 0.0 0.2 0.0 1.8 4.2 0.0 0.0 0.0 0.0 8.7 2.9 15.6 10.7 0.1 0.4 11.4 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.2 0.0 1.6 0.9 1.8 0.0 2.5 0.8 0.2 0.0 0.7 0.2 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 1.4 0.0 15.6 40.5 32.5 21.4 13.8 30.8 42.6 37.4 39.2 22.6 27.7 65.3 7.0 19.2 4.4 44.4 0.9 1.3 0.8 0.0 0.6 14.8 2.0 1.8 159.0 1.5 1.9 14.7 0.0 0.1 0.8 1.8 58.7 0.9 15.5 2.0 102.7 5.4 1.8 0.0 201.0 0.4 0.0 6.0 1.1 1.9 6.3 3.8 0.4 0.0 3.1 15.2 160.9 0.0 2.0 4.1 2.0 3.8 1.8 4.6 0.0 49.6 2.9 2.7 0.0 181.5 2062.6 0.2 0.0 7.9 3.8 0.6 0.6 52.4 2.2 1.2 32.9 5.4 31.8 1.0 1.8 0.2 1.3 0.1 8.2 1.6 0.1 0.3 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 380.7;Extravillous trophoblasts: 257.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "NK-cell: 9.1" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1060.6;T-47d: 396.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 24.3 8.4 25.6 7.4 35.7 9.3 40.6 6.4 31.2 37.9 16.4 11.8 9.3 29.0 9.3 35.5 21.0 32.1 54.7 44.4 10.4 15.7 31.1 32.3 7.2 8.1 12.3 19.3 23.4 5.9 6.3 47.6 8.4 17.7 14.6 2.1 42.9 10.5 7.4 47.3 12.9 26.6 7.3 83.6 10.4 38.1 11.8 7.2 18.0 13.6 7.6 29.8 32.1 16.8 131.1 115.6 38.3 3.1 19.9 31.9 15.1 27.1 44.8 86.3 49.8 8.6 112.1 0.0 176.3 95.2 208.3 159.8 1.7 61.5 75.6 0.3 3.5 0.0 50.8 9.7 106.1 0.6 3.6 18.7 82.0 33.3 90.9 1060.6 175.4 0.0 0.1 4.4 169.8 47.5 0.3 0.2 7.6 12.4 18.5 6.3 106.5 0.0 221.6 25.4 2.3 5.1 82.4 16.0 76.0 66.1 396.9 2.0 231.9 24.3 63.8 11.0 217.8 0.1 0.3 0.3 18.8 0.3 110.7 2.2 0.5 1.9 0.1 1.2 0.0 0.8 0.5 0.0 2.2 0.6 0.9 0.4 1.5 9.1 0.5 1.5 0.4 0.4 25.6 35.7 6.4 31.2 44.4 10.4 8.1 12.3 8.4 7.3 11.8 16.8 144.6 19.2 15.8 5.9 23.4 141.7 194.1 116.1 380.7 3.8 108.5 203.7 128.9 30.0 134.9 18.4 4.2 66.5 22.7 66.3 9.8 109.8 10.9 132.7 67.8 178.7 84.3 2.7 44.3 77.9 257.3 107.8 136.6 165.4 9.5 4.1 89.3 7.7 14.9 0.0 22.8 39.9 124.1 8.1 19.3 5.0 12.8 39.5 24.9 15.9 3.2 3.3 0.0 3.5 4.9 103.2 44.6 10.9 8.2 76.1 38.5 5.5 31.6 2.9 0.0 74.0 106.6 65.1 10.4 184.9 103.4 129.8 21.2 7.4 45.6 63.1 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 299.3;Fibroblasts: 63.8;Sertoli cells: 46.0;Skeletal myocytes: 96.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.2;MOLT-4: 3.0;U-87 MG: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012805 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" "HPA012805: AB_1857893" "unprognostic (4.28e-1)" "unprognostic (3.55e-1)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (6.07e-3)" "unprognostic (4.62e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (9.15e-8)" "unprognostic (9.37e-3)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" 6.3 2.8 6.7 3.3 7.9 1.1 8.3 10.0 11.6 5.3 4.6 5.2 1.8 12.6 3.8 12.2 11.5 14.3 21.7 6.0 6.1 5.5 0.6 4.2 5.4 6.8 10.4 14.9 3.5 6.7 2.8 2.2 7.8 5.4 2.9 48.4 4.1 5.1 8.1 4.2 5.3 10.8 5.1 1.8 4.5 5.7 8.3 23.1 3.1 18.4 5.3 4.0 4.6 8.0 0.1 0.0 0.1 1.4 0.2 0.0 0.2 0.1 9.2 0.6 0.4 0.1 2.2 0.1 0.2 0.3 0.0 0.2 0.2 0.1 0.5 0.0 0.7 0.2 0.6 0.1 0.2 0.3 0.1 0.3 0.1 0.4 0.1 0.1 0.0 0.9 0.0 0.6 0.0 1.1 3.0 0.3 0.3 0.1 0.0 0.3 0.4 0.4 0.0 0.1 1.4 0.1 0.0 0.2 0.0 0.1 0.2 0.2 0.0 1.1 0.6 0.4 0.2 0.1 0.0 0.1 5.9 0.4 0.1 0.3 0.1 0.1 1.8 0.0 1.5 0.1 0.5 0.6 0.0 0.1 2.1 2.2 0.4 1.1 0.0 0.9 0.0 0.8 6.7 7.9 10.0 11.6 6.0 6.1 6.8 10.4 7.8 5.1 8.3 8.0 3.4 0.0 14.9 2.9 0.7 5.2 0.9 0.2 2.8 299.3 1.6 1.8 6.9 0.0 1.9 0.0 20.9 0.1 5.4 0.1 0.0 0.0 2.2 0.2 2.4 14.4 0.0 2.7 16.6 0.2 0.1 63.8 2.0 0.3 1.3 0.2 0.4 0.2 0.1 6.7 16.3 0.0 2.0 1.3 6.9 9.1 0.6 7.9 7.2 35.6 5.2 12.2 18.6 3.0 1.4 0.1 0.0 1.2 2.0 0.9 0.0 0.1 1.5 24.2 46.0 96.1 29.3 0.7 0.7 1.2 4.4 0.0 12.1 0.4 0.0 0.5 PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" 84.4 29.4 14.4 25.6 13.8 38.1 77.0 11.8 16.4 53.7 11.6 46.7 18.4 47.1 7.5 38.3 44.6 21.6 39.3 13.8 13.1 35.4 25.4 75.2 25.6 18.2 13.8 37.5 20.3 8.3 26.8 23.7 14.8 41.5 8.5 3.9 44.2 17.2 22.5 47.4 39.0 19.5 14.6 48.6 35.3 11.3 15.2 17.0 48.1 7.9 15.2 42.7 44.5 13.1 37.2 13.8 11.8 11.4 30.2 43.2 40.6 18.5 31.6 55.9 63.3 14.6 64.2 16.4 63.7 31.6 53.3 66.6 16.3 37.1 7.6 58.0 25.1 35.8 21.3 16.3 36.9 33.9 31.1 83.7 24.8 37.5 19.2 39.3 38.3 26.1 30.6 28.3 32.7 17.3 28.3 52.6 12.8 7.7 25.0 21.6 13.4 30.8 60.3 59.5 10.1 11.1 29.7 16.3 44.8 10.3 12.8 28.7 66.1 56.6 15.5 28.5 38.1 29.4 20.0 8.0 38.9 42.2 18.2 7.4 14.7 23.4 13.0 20.2 9.8 12.4 10.4 14.1 14.5 10.2 8.2 8.5 12.0 14.5 22.6 9.2 14.3 10.1 14.4 13.8 11.8 16.4 13.8 13.1 18.2 13.8 14.8 14.6 15.2 13.1 127.8 16.0 12.2 8.8 24.9 22.9 14.3 30.4 37.5 8.1 13.5 12.8 10.0 5.7 16.7 5.5 2.1 9.4 18.8 13.1 7.9 25.8 3.4 16.0 16.7 48.0 14.3 29.3 4.7 19.1 15.0 20.7 58.1 26.0 12.0 11.5 32.2 11.3 30.8 8.4 4.8 14.3 14.2 20.1 18.5 4.0 27.7 19.6 7.2 7.5 24.6 8.5 20.6 4.5 6.0 62.8 15.5 24.0 21.6 26.2 22.8 10.4 18.3 5.4 39.5 7.7 20.4 1.1 4.0 27.1 19.6 4.9 20.4 16.8 12.1 26.0 PNMA8A "FLJ10781, KIAA1183L, PNMAL1" ENSG00000182013 "PNMA family member 8A" Q86V59 19 46466491-46471563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Endometrial ciliated cells: 8.4;Granulosa cells: 13.5;Respiratory ciliated cells: 10.9;Theca cells: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 32.9;K-562: 36.3;LHCN-M2: 35.9;SH-SY5Y: 31.3" "Low region specificity" "Detected in all" "HPA012956, HPA077702" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA012956: AB_1844328, HPA077702: " "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "unprognostic (9.35e-3)" "unprognostic (1.01e-1)" "unprognostic (6.90e-3)" "unprognostic (1.76e-3)" "unprognostic (9.56e-2)" "unprognostic (1.78e-2)" "unprognostic (2.85e-2)" "unprognostic (1.82e-1)" "unprognostic (6.48e-3)" 1.1 22.8 45.8 0.9 44.8 0.7 4.7 16.2 54.3 5.8 13.9 3.6 0.7 12.5 16.2 1.2 22.1 5.2 15.0 45.4 53.9 8.7 0.4 1.7 0.3 27.0 30.1 17.2 6.3 15.8 36.7 2.6 35.3 8.8 0.7 35.6 6.0 9.6 1.6 1.2 1.3 7.2 23.3 0.6 1.8 22.5 39.8 30.1 15.4 1.1 0.6 3.1 1.6 34.6 0.0 13.9 19.7 19.6 5.6 12.7 3.5 1.3 0.2 2.4 1.2 0.2 1.6 0.1 18.1 0.9 6.8 0.2 32.9 5.3 1.6 0.1 12.2 0.0 0.5 0.5 9.4 0.2 0.2 3.3 6.5 8.2 0.0 1.8 2.0 11.9 36.3 0.2 35.9 0.1 0.2 0.2 16.5 0.0 0.0 0.0 21.5 0.0 8.2 0.1 16.0 31.3 0.1 0.3 0.0 18.0 0.2 0.3 1.2 0.0 0.2 0.2 6.8 0.1 0.1 0.2 0.3 0.1 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.0 45.8 44.8 16.2 54.3 45.4 53.9 27.0 30.1 35.3 23.3 39.8 34.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 0.0 0.0 1.8 11.0 0.0 1.9 0.0 0.0 3.9 0.9 0.0 8.4 2.3 0.3 0.0 0.0 0.0 0.0 0.5 2.8 0.0 1.3 0.0 13.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 8.6 0.0 0.0 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477089 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 333.9;epididymis: 594.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 360.6;Erythroid cells: 227.3;Syncytiotrophoblasts: 646.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 531.3;U-937: 593.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol NA NA 58000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favorable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 78.6 24.8 16.1 46.8 16.6 333.9 34.6 22.6 22.7 25.3 18.9 52.2 120.3 14.2 594.8 87.4 18.2 56.8 29.0 17.7 19.6 206.8 98.0 48.6 46.7 20.3 18.1 5.0 23.2 32.0 19.8 132.6 20.1 15.0 61.8 27.1 22.6 27.4 7.3 29.6 60.3 38.7 23.1 44.5 50.6 7.4 21.1 33.5 17.8 10.0 64.4 100.4 41.5 20.1 86.1 113.4 24.0 53.9 26.0 21.0 71.8 85.2 40.3 68.2 67.0 66.1 76.5 227.1 96.8 45.5 81.5 89.9 125.2 159.8 89.5 75.0 109.6 189.1 89.9 109.3 24.2 531.3 94.7 14.4 57.4 206.0 91.0 37.8 295.9 141.0 95.4 137.4 86.7 79.1 157.6 311.3 67.5 215.7 186.1 130.2 35.9 88.3 243.7 79.6 101.9 22.6 163.4 205.0 13.2 32.6 75.5 92.5 240.0 46.1 62.6 105.1 148.4 63.1 113.3 258.9 39.3 593.0 4.6 12.0 30.6 10.3 39.8 27.3 73.6 25.7 44.2 45.0 48.1 28.8 27.6 35.9 3.7 38.5 26.6 27.3 16.7 31.1 16.1 16.6 22.6 22.7 17.7 19.6 20.3 18.1 20.1 23.1 21.1 20.1 149.6 0.0 23.5 5.9 50.3 84.6 67.4 12.6 112.7 4.7 56.3 62.6 3.5 27.1 13.4 82.8 14.6 360.6 45.2 61.1 39.2 43.2 1.3 36.0 12.7 139.4 46.4 227.3 0.6 51.5 41.8 32.4 106.5 65.3 57.7 5.0 24.3 30.6 70.9 16.8 1.1 51.3 18.3 18.1 58.4 0.8 0.3 83.3 30.2 3.7 13.2 78.8 29.9 3.0 0.9 130.8 83.9 0.7 88.6 27.5 41.2 118.9 10.5 18.1 0.0 23.9 41.3 0.4 0.7 114.7 63.9 646.2 62.3 3.1 51.4 77.1 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Proximal tubular cells: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 20.8 27.6 11.9 9.7 12.6 8.7 22.6 12.0 11.8 13.9 16.9 15.4 18.9 14.0 18.1 21.0 24.7 9.4 42.1 11.1 14.2 41.2 40.1 9.8 10.8 12.1 13.5 22.4 28.8 25.2 13.5 8.0 12.4 12.8 12.3 16.8 26.9 10.8 77.9 15.0 11.4 12.1 12.5 9.4 19.5 7.8 15.6 16.3 29.9 66.0 10.2 8.9 13.3 11.9 44.7 18.1 2.8 44.4 0.9 0.5 11.9 13.7 1.5 23.0 14.1 18.1 16.1 13.9 0.1 4.5 0.3 25.7 0.0 45.6 39.2 0.4 32.0 10.0 32.8 38.6 28.6 17.8 14.1 29.5 45.7 11.7 27.3 5.5 16.2 0.3 39.9 0.5 0.3 11.8 0.3 17.2 46.9 30.7 38.0 0.3 0.2 15.6 30.6 20.3 25.3 12.7 41.2 16.8 23.7 49.7 26.1 13.0 9.4 0.2 11.4 35.5 0.2 20.3 0.3 27.0 0.2 0.1 3.7 7.4 11.4 9.7 6.1 13.5 7.0 14.7 8.7 6.7 22.2 16.7 11.3 10.8 0.7 11.9 12.5 16.3 6.0 9.3 11.9 12.6 12.0 11.8 11.1 14.2 12.1 13.5 12.4 12.5 15.6 11.9 10.7 9.6 12.5 3.3 8.2 11.9 16.7 46.0 17.6 11.3 38.2 33.5 55.0 20.0 24.3 20.2 0.0 28.7 7.8 31.2 95.9 34.2 3.1 35.9 20.6 10.6 19.8 15.6 2.8 48.7 21.3 14.6 13.7 15.5 8.2 17.3 13.2 62.1 28.7 10.1 3.6 30.6 38.7 9.2 10.2 3.7 16.4 12.1 17.8 1.0 13.3 36.1 6.2 2.5 1.0 39.8 25.1 20.3 14.2 15.3 47.6 126.4 31.0 15.0 6.6 6.6 14.6 22.2 21.4 24.0 16.8 14.0 6.4 49.0 32.3 16.0 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POT1 "DKFZp586D211, hPot1" ENSG00000128513 "Protection of telomeres 1" Q9NUX5 7 124822386-124929983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 41.5;Oligodendrocytes: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068538 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068538: AB_2686001" "unprognostic (1.39e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-3)" "unprognostic (7.88e-2)" "unprognostic (2.26e-2)" "unprognostic (1.51e-1)" "unprognostic (2.48e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-2)" "unprognostic (4.77e-3)" "unprognostic (7.42e-2)" 5.6 5.7 3.2 5.7 3.8 4.1 10.4 3.7 3.6 7.9 4.0 5.6 4.5 9.5 6.1 4.5 8.1 6.0 6.2 3.2 4.2 9.7 9.9 6.1 8.8 3.9 3.4 10.1 5.3 9.8 6.4 6.9 4.1 7.1 6.4 9.9 3.9 6.7 3.2 4.1 4.2 7.2 3.8 8.1 5.8 13.8 3.2 13.0 12.9 4.4 9.6 7.7 4.5 6.1 24.0 6.9 14.0 9.9 9.2 16.2 10.3 12.1 14.9 14.3 19.7 7.3 25.9 24.4 8.5 11.1 23.6 9.5 14.8 15.0 21.7 21.4 17.5 18.9 10.3 3.2 15.4 22.6 12.4 13.1 13.6 12.8 21.8 14.5 16.6 10.1 38.1 51.9 15.0 4.1 29.8 12.5 17.4 13.2 14.1 19.1 14.0 27.5 9.9 9.8 13.9 16.6 18.7 19.8 15.6 20.3 8.0 12.3 8.4 14.3 5.5 19.1 17.1 23.2 27.0 39.8 20.4 23.6 22.7 0.6 2.2 1.0 2.3 2.3 4.3 3.2 2.6 3.0 2.5 2.5 4.3 3.0 0.4 3.7 1.8 2.2 2.8 1.9 3.2 3.8 3.7 3.6 3.2 4.2 3.9 3.4 4.1 3.8 3.2 6.1 9.7 6.4 4.1 36.9 10.1 4.6 6.7 5.5 13.1 9.2 7.1 7.1 8.8 8.6 3.6 12.9 10.4 7.0 8.0 1.5 19.6 5.0 19.3 4.3 6.9 7.1 9.0 16.0 34.7 4.5 8.0 6.9 8.2 4.2 3.8 9.4 7.1 10.5 6.3 8.4 41.5 4.0 2.0 10.9 7.0 8.3 8.7 8.7 16.0 24.4 5.6 12.6 4.1 37.2 66.8 3.8 1.7 4.5 7.6 2.8 0.8 11.2 4.9 10.0 0.0 5.4 6.3 35.2 14.4 7.6 2.6 4.5 8.5 4.8 4.9 3.5 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 65.9;Respiratory ciliated cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Vesicles, Cytosol" "HPA030123: AB_10603987" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 9.3 17.1 24.2 3.5 24.5 25.2 10.3 25.2 38.2 14.5 24.7 12.7 3.9 10.9 8.3 8.9 22.0 4.7 13.1 24.4 24.7 15.5 11.5 8.6 5.7 25.0 25.0 13.8 10.8 7.2 13.7 6.5 24.6 13.4 3.9 12.6 8.7 7.7 7.6 11.2 8.5 6.6 25.0 13.6 10.9 6.9 24.0 5.0 11.9 5.6 5.2 11.6 9.6 25.4 10.0 8.0 12.7 8.5 10.4 9.3 3.5 5.9 5.7 7.5 10.3 10.4 9.3 7.4 14.3 5.3 4.1 6.3 9.8 8.8 7.1 4.6 20.3 9.0 18.9 23.9 8.6 3.0 4.6 7.6 11.0 6.3 9.4 9.4 14.7 7.0 22.8 11.2 5.6 9.2 12.0 8.6 8.2 11.2 18.8 13.6 8.2 16.7 15.1 4.2 9.8 14.7 6.6 10.3 12.0 14.6 19.9 9.5 5.7 6.5 7.1 6.5 7.5 19.4 15.3 10.5 6.8 6.0 4.9 6.3 7.2 5.3 10.4 7.6 7.2 9.0 7.8 7.6 10.4 8.2 6.8 6.9 2.9 12.0 5.2 6.6 16.1 7.8 24.2 24.5 25.2 38.2 24.4 24.7 25.0 25.0 24.6 25.0 24.0 25.4 10.9 3.2 13.7 10.4 9.8 12.0 8.3 16.6 9.1 18.0 12.1 14.1 10.1 4.3 15.6 7.3 22.9 21.4 10.6 3.6 21.5 9.5 9.8 39.1 5.9 8.3 6.0 65.9 5.9 5.6 9.4 9.1 5.1 4.6 6.3 12.3 8.9 6.1 9.3 15.2 7.5 7.3 26.4 4.7 8.4 12.1 10.2 8.0 1.8 5.6 8.1 10.4 8.2 9.0 8.9 6.3 3.8 6.8 16.9 3.2 6.6 17.2 84.4 20.9 6.6 9.6 15.6 12.8 9.3 7.2 14.9 10.4 10.6 11.1 7.5 6.2 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PPP1R3B "FLJ14005, GL, PPP1R4" ENSG00000173281 "Protein phosphatase 1 regulatory subunit 3B" Q86XI6 8 9136255-9151574 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.9;skeletal muscle: 95.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 69.9;Hepatocytes: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 53.6;eosinophil: 15.8;neutrophil: 50.4" "Lineage enriched" "Detected in all" 19 "granulocytes: 53.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 47.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028731 Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA028731: AB_10602120" "unprognostic (4.97e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.39e-1)" "unprognostic (5.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.08e-7)" "prognostic unfavorable (6.03e-5)" "unprognostic (3.33e-1)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" 24.1 7.5 1.9 8.2 2.8 12.3 15.9 3.4 3.8 19.6 5.9 16.1 4.6 19.8 4.4 17.2 12.9 9.0 29.9 1.7 3.1 7.6 144.9 9.2 4.3 4.8 3.0 10.4 5.1 50.1 3.3 10.4 4.1 21.7 9.5 7.1 13.9 18.6 95.4 12.3 7.2 12.0 3.1 7.7 12.0 7.1 3.9 4.5 11.7 17.7 3.6 26.4 15.0 4.5 6.7 2.5 7.3 2.5 17.9 15.1 26.3 2.4 7.9 2.9 3.5 10.0 3.1 2.3 3.9 5.0 16.1 1.2 1.3 1.9 3.1 7.2 1.1 4.0 1.0 0.0 8.0 2.0 17.1 12.4 5.9 2.5 14.6 22.0 47.3 11.6 3.1 5.6 1.1 4.1 11.2 3.8 10.6 15.2 2.2 4.5 9.2 4.0 28.6 26.9 0.0 13.6 4.4 0.1 18.6 11.6 3.4 4.1 32.9 8.5 2.9 1.7 3.1 3.1 7.5 0.0 14.8 6.2 2.6 53.6 1.6 15.8 2.2 1.1 1.8 1.6 2.0 1.2 0.9 1.2 2.7 1.5 50.4 2.2 0.7 1.8 1.5 1.6 1.9 2.8 3.4 3.8 1.7 3.1 4.8 3.0 4.1 3.1 3.9 4.5 16.7 12.8 34.5 0.7 5.5 10.7 18.8 7.2 3.4 3.7 19.4 12.7 69.9 24.3 21.8 9.2 6.2 12.9 7.6 26.7 3.9 8.8 20.3 29.5 21.9 21.0 0.0 0.8 0.8 12.7 38.3 12.7 9.7 51.7 33.6 10.4 31.1 184.7 6.9 6.7 0.4 11.5 8.2 9.8 27.9 5.2 9.6 15.6 5.4 3.7 3.1 3.9 4.1 3.5 1.4 18.4 7.5 18.0 4.5 8.0 7.4 6.8 30.8 13.0 13.1 10.9 17.9 1.7 5.7 0.6 12.1 18.3 10.8 9.4 5.5 2.2 PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633071 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 908.0;tongue: 448.5" "Group enriched" "Detected in many" 8 "Astrocytes: 201.8;Cardiomyocytes: 232.0;Hepatocytes: 64.2;Muller glia cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 41.9;HHSteC: 51.7;hTERT-RPE1: 85.4;LHCN-M2: 102.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027041 Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027041: AB_1855649" "unprognostic (2.11e-1)" "unprognostic (1.86e-3)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.15e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.38e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-3)" "unprognostic (5.63e-3)" "unprognostic (1.59e-2)" "unprognostic (5.48e-3)" "unprognostic (8.44e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" 14.1 12.2 39.3 3.4 51.5 0.0 9.9 39.8 44.6 97.1 21.4 16.2 4.0 10.3 12.0 106.8 10.2 14.4 170.5 40.1 42.9 11.6 164.2 12.3 1.4 44.1 55.1 10.2 18.7 4.5 5.7 15.6 43.9 29.1 4.1 83.2 28.4 35.7 908.0 17.0 5.8 15.4 39.6 3.0 17.5 2.5 42.4 0.5 2.7 448.5 6.2 19.8 136.7 38.0 0.0 6.6 1.8 26.8 11.9 5.6 0.0 29.8 23.2 12.0 12.8 0.0 2.2 0.0 1.2 28.0 4.8 1.6 0.7 3.2 22.0 0.0 0.1 0.4 41.9 4.8 51.7 0.0 0.0 19.1 5.2 7.6 0.4 85.4 3.0 0.0 14.4 0.0 102.5 1.0 0.0 0.0 1.7 0.0 0.0 0.0 6.4 0.0 1.1 26.2 0.9 1.8 0.0 0.0 0.0 0.0 0.2 4.5 20.3 5.3 5.2 7.0 4.3 0.2 0.6 0.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 51.5 39.8 44.6 40.1 42.9 44.1 55.1 43.9 39.6 42.4 38.0 2.4 0.0 0.0 201.8 0.4 4.6 9.3 0.8 0.6 9.7 4.8 2.5 232.0 1.5 0.2 3.7 0.0 0.2 0.0 0.3 7.9 3.1 0.1 0.3 0.7 3.5 10.1 0.0 1.7 11.4 0.5 11.9 0.0 0.6 0.0 0.4 2.5 64.2 1.4 18.5 3.0 0.5 2.0 1.6 1.5 0.1 2.8 0.6 12.4 5.6 0.0 133.1 0.0 3.5 0.5 4.0 0.1 7.5 0.0 2.5 0.0 1.8 0.4 12.8 0.0 9.4 18.6 0.7 1.7 5.4 4.0 0.3 0.7 0.1 0.1 0.7 PPP1R3G ENSG00000219607 "Protein phosphatase 1 regulatory subunit 3G" B7ZBB8 6 5085341-5089487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.9;liver: 6.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.5;Glandular and luminal cells: 7.2" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.3;PC-3: 3.9;THP-1: 14.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056393 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA056393: AB_2683115" "unprognostic (1.99e-2)" "unprognostic (5.50e-3)" "unprognostic (2.10e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (6.56e-3)" "unprognostic (8.64e-3)" "unprognostic (1.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.04e-2)" "unprognostic (3.71e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-2)" "unprognostic (5.56e-2)" "unprognostic (3.17e-3)" "unprognostic (1.27e-1)" 2.3 3.0 2.3 0.3 2.1 0.1 1.4 1.5 2.7 2.1 0.9 2.0 0.2 1.2 1.0 1.8 1.0 0.3 5.9 2.0 1.8 0.6 6.2 0.3 0.5 2.3 2.3 0.8 0.1 0.3 0.2 0.7 1.9 1.2 0.5 0.2 0.6 1.4 0.5 1.2 0.5 0.5 1.6 2.8 0.6 0.2 2.2 0.2 0.3 0.2 0.4 2.8 2.1 1.7 0.0 0.2 0.1 0.0 1.6 1.0 0.0 0.3 0.4 0.2 0.3 0.0 0.3 0.0 3.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.3 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 3.9 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 14.6 0.0 0.0 0.0 0.8 0.5 2.0 1.7 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 2.3 2.1 1.5 2.7 2.0 1.8 2.3 2.3 1.9 1.6 2.2 1.7 4.2 0.0 0.0 0.0 0.4 0.5 0.5 0.4 0.0 0.5 0.2 0.1 18.5 0.0 0.1 3.7 0.0 0.8 0.0 1.3 0.0 0.3 0.0 1.2 2.0 1.9 1.2 0.0 0.0 0.0 0.4 3.7 0.0 7.2 0.0 1.4 2.9 0.0 4.5 0.0 0.0 0.9 0.0 4.0 4.7 0.2 0.9 1.8 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.6 1.8 3.0 1.8 0.4 0.0 2.1 0.2 0.2 0.0 2.0 2.5 0.1 0.9 0.2 0.3 0.8 0.2 0.5 1.4 1.2 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 51.2;skeletal muscle: 180.5;tongue: 117.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 37.4;BJ hTERT+: 35.3;RPTEC TERT1: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 3.1 3.4 3.3 2.3 7.2 0.2 7.1 4.3 5.0 5.2 3.9 8.0 2.0 7.7 5.1 8.3 4.1 5.0 51.2 4.2 4.9 22.0 1.1 3.9 0.6 5.7 5.5 5.6 3.4 11.7 1.8 2.8 5.3 5.9 5.4 2.6 8.9 6.5 180.5 18.9 2.3 9.6 4.3 1.1 7.4 7.2 6.0 0.6 3.1 117.6 1.2 4.5 4.0 13.7 37.4 2.0 10.3 5.0 8.1 10.2 11.9 28.5 35.3 13.2 16.3 2.4 2.4 0.1 10.7 29.3 9.5 4.7 4.3 10.0 28.3 0.1 1.4 1.6 1.0 0.1 5.8 0.0 1.4 9.3 8.5 16.8 7.8 13.3 12.8 1.0 1.0 0.1 19.2 6.2 0.3 0.2 7.2 0.4 6.9 0.1 15.1 0.1 46.2 1.4 0.7 5.7 4.7 5.7 10.9 9.2 9.1 0.5 8.4 13.7 7.5 18.8 12.7 0.4 1.0 0.1 10.1 0.8 4.9 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 3.3 7.2 4.3 5.0 4.2 4.9 5.7 5.5 5.3 4.3 6.0 13.7 7.9 28.9 27.6 51.6 2.8 26.4 19.5 7.1 19.4 5.7 19.9 15.5 115.3 8.6 10.0 55.2 0.0 10.9 6.7 25.3 21.5 20.6 8.4 9.9 19.0 11.4 13.1 0.4 35.2 9.9 15.4 14.8 21.9 16.1 3.8 15.7 8.6 2.9 2.5 3.3 47.2 6.9 6.1 2.4 9.8 10.7 24.5 3.2 28.4 13.1 9.6 8.9 2.1 72.4 201.1 17.2 10.6 18.4 1.5 17.8 21.7 40.1 8.1 2.6 6.6 29.0 14.0 10.1 18.6 15.3 33.2 10.4 3.4 6.7 8.9 15.6 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436433-73496024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 379.3;tongue: 179.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 44.8 37.5 40.5 29.8 51.1 19.8 32.1 49.5 63.1 30.3 26.7 41.4 24.2 40.3 34.5 33.1 30.9 28.3 41.3 56.9 29.5 28.1 21.8 23.5 34.9 25.4 25.2 39.6 25.3 39.2 30.6 25.5 28.7 39.1 29.6 57.0 26.6 39.8 379.3 26.3 22.6 48.2 27.2 25.3 24.3 29.0 29.1 32.9 23.5 179.7 36.1 34.3 24.3 44.9 53.7 29.0 50.9 53.0 71.4 98.3 24.5 48.0 65.7 46.1 45.4 18.6 26.8 47.1 15.3 70.0 21.8 28.1 41.6 36.9 64.5 66.6 34.0 20.3 25.0 35.5 42.7 45.2 40.2 70.1 43.5 43.6 58.1 84.7 32.3 40.6 25.6 54.0 94.1 16.9 40.7 41.6 20.7 23.3 83.8 26.9 27.7 22.4 45.1 25.6 27.2 31.5 28.1 69.5 36.4 42.1 52.4 43.2 35.6 36.6 33.7 29.5 66.1 35.8 105.3 33.0 45.3 64.0 21.3 2.2 2.0 3.5 4.0 2.7 4.8 2.7 4.3 4.4 2.1 2.3 3.4 5.1 1.1 3.5 1.7 4.0 7.8 1.9 40.5 51.1 49.5 63.1 56.9 29.5 25.4 25.2 28.7 27.2 29.1 44.9 23.0 3.2 14.3 72.5 31.6 25.6 29.8 13.2 27.3 54.8 25.7 16.9 48.9 14.3 12.8 18.4 20.9 21.0 23.7 11.1 62.6 18.1 11.8 20.0 24.2 21.5 42.6 30.7 119.5 19.4 16.8 32.6 20.4 18.8 21.0 35.4 18.9 14.2 20.3 38.7 111.0 13.2 18.3 31.7 24.2 9.9 33.5 25.2 26.6 51.5 29.6 34.8 18.6 79.4 54.4 16.7 12.9 29.0 34.1 27.1 13.4 34.2 17.6 30.1 6.6 41.8 36.4 43.8 49.2 32.1 31.5 22.2 27.3 28.4 13.1 22.1 PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Early spermatids: 75.6;Inhibitory neurons: 31.9;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Cell line enhanced" "Detected in many" "U-266/84: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" 3.0 4.0 1.8 1.6 2.0 3.5 3.0 3.2 2.0 5.2 4.2 3.2 1.3 6.0 2.8 2.2 4.6 2.4 3.0 1.6 3.2 1.9 0.4 4.2 0.9 4.1 4.0 10.3 4.8 8.6 3.9 3.5 4.0 4.1 2.9 4.7 1.8 4.3 1.6 1.5 1.8 4.4 4.7 2.4 2.1 3.6 2.9 1.4 5.8 3.0 0.8 2.9 3.3 4.4 2.2 3.4 7.8 0.1 4.5 9.3 9.2 4.7 9.9 4.7 4.2 4.4 1.2 0.4 1.2 6.2 4.5 0.1 0.0 1.0 6.0 0.0 1.4 2.9 3.1 0.3 4.9 10.0 0.1 6.6 2.9 3.3 4.1 4.3 3.4 1.2 0.0 14.2 5.7 0.4 1.5 0.1 5.7 0.8 2.7 0.0 9.3 6.1 1.6 0.0 1.4 6.2 0.0 0.1 0.9 4.0 6.4 4.1 1.4 0.2 2.7 4.8 4.6 13.0 19.7 0.1 3.6 0.1 3.6 0.1 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 1.8 2.0 3.2 2.0 1.6 3.2 4.1 4.0 4.0 4.7 2.9 4.4 7.1 12.8 5.6 51.2 0.5 1.7 2.7 2.4 9.1 9.1 1.1 2.4 8.2 2.8 3.8 1.8 8.4 1.0 0.2 1.5 1.9 2.3 75.6 1.4 9.4 6.3 3.6 0.0 25.0 2.5 2.6 9.6 2.6 1.4 2.5 15.5 3.6 0.0 0.8 0.0 31.9 3.6 4.1 0.3 0.7 31.0 8.7 0.6 1.8 23.4 0.2 7.6 0.0 52.8 8.0 1.5 0.8 9.4 0.7 2.6 0.1 0.2 1.8 7.5 6.6 10.1 6.6 8.2 3.5 4.6 1.7 0.5 1.2 14.9 3.0 0.7 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PRSS45P "PRSS45, TESPL, TESSP5" ENSG00000188086 "Serine protease 45, pseudogene" Q7RTY3 3 46742092-46750891 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 6.4;skeletal muscle: 10.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA060284 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "HPA060284: AB_2684242" "unprognostic (4.55e-3)" "unprognostic (3.49e-2)" "unprognostic (1.07e-2)" "unprognostic (2.50e-1)" "unprognostic (6.07e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (6.20e-2)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-4)" "unprognostic (2.33e-2)" "unprognostic (6.60e-3)" "unprognostic (1.27e-2)" "unprognostic (1.57e-2)" "unprognostic (2.15e-1)" "unprognostic (5.97e-3)" 0.3 0.2 0.3 0.0 0.3 0.0 1.1 0.5 0.4 1.6 1.0 0.5 0.1 0.3 6.4 0.2 0.9 0.0 3.5 0.2 0.7 1.7 1.3 0.6 0.1 0.6 0.7 0.4 2.1 2.8 1.9 0.1 0.7 1.4 0.0 0.2 0.9 1.0 10.4 0.3 0.3 0.1 0.5 0.3 0.3 2.2 0.6 0.2 4.9 0.9 0.0 0.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.2 0.7 0.6 0.7 0.7 0.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.1;Oligodendrocyte precursor cells: 111.6;Oligodendrocytes: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cell line enhanced" "Detected in many" "CACO-2: 75.9;CAPAN-2: 94.3;HEL: 56.2" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" 5.4 22.2 21.7 4.5 28.7 0.9 7.6 24.9 27.2 12.9 16.1 9.9 17.7 15.8 7.4 5.5 9.8 14.8 10.9 22.4 24.6 4.8 2.8 4.3 4.2 26.7 24.0 20.2 4.6 13.4 11.4 2.9 28.0 7.8 11.3 16.5 9.7 8.2 1.3 1.8 17.1 9.8 25.8 3.2 17.5 2.2 23.7 6.8 5.3 2.8 3.2 7.4 6.3 37.1 19.5 41.3 30.2 12.4 4.9 24.4 0.0 20.2 15.1 14.2 19.3 75.9 94.3 0.0 3.1 23.7 1.2 10.7 34.7 0.0 22.0 0.0 1.4 56.2 7.6 0.1 14.6 0.0 0.0 7.1 0.2 7.7 0.0 13.3 22.6 2.2 18.6 10.5 6.8 0.5 8.8 0.1 20.9 3.3 0.7 9.7 0.1 0.2 12.7 0.5 21.5 0.9 19.3 0.1 0.0 0.6 1.1 4.3 12.2 6.3 15.5 23.1 12.2 0.9 0.0 0.0 16.8 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 4.4 0.0 0.1 0.0 0.9 21.7 28.7 24.9 27.2 22.4 24.6 26.7 24.0 28.0 25.8 23.7 37.1 3.5 0.0 0.5 136.1 0.7 2.7 4.6 5.4 2.8 10.2 1.1 5.8 8.6 7.2 3.9 3.7 2.1 1.0 0.8 3.8 5.9 5.8 1.4 1.5 27.3 2.8 5.4 3.0 38.2 0.5 4.9 20.6 12.2 2.2 0.0 25.1 7.5 0.1 7.2 6.7 43.0 7.3 0.0 0.9 3.1 1.0 12.2 7.8 3.6 24.4 1.5 45.8 0.0 111.6 148.2 2.3 2.1 9.8 1.3 1.1 12.2 0.1 1.1 15.9 0.0 16.4 10.4 3.4 6.3 0.4 2.8 0.8 1.0 22.7 11.6 1.5 PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4" "Cell type enhanced" "Detected in many" "Astrocytes: 558.3;Early spermatids: 686.7;Excitatory neurons: 284.7;Oligodendrocyte precursor cells: 488.1;Oligodendrocytes: 584.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.8;hTERT-RPE1: 48.0;LHCN-M2: 47.3;U-87 MG: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA002455: AB_2666597" "unprognostic (3.87e-2)" "unprognostic (2.52e-2)" "prognostic favorable (7.55e-4)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.56e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (7.27e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-3)" "unprognostic (2.13e-1)" "unprognostic (7.18e-3)" "unprognostic (3.71e-2)" "unprognostic (8.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" 2.4 17.8 24.8 3.1 46.2 1.2 5.9 62.4 46.1 11.9 0.0 6.7 4.8 8.8 3.8 5.3 2.5 7.4 27.5 51.9 4.0 1.9 18.9 4.6 2.5 3.3 10.0 18.0 9.9 18.4 7.3 6.6 1.8 3.9 7.3 19.9 4.1 5.8 1.3 4.4 5.0 5.8 0.0 10.4 9.8 16.4 7.8 2.2 6.1 2.3 3.4 5.8 4.3 17.2 11.0 5.7 25.0 0.1 8.8 53.8 1.3 5.7 8.9 5.1 10.5 3.3 4.3 6.5 3.6 23.8 22.3 0.9 7.3 10.1 9.7 0.0 6.6 0.6 4.6 0.5 15.9 0.2 0.4 14.2 6.2 28.2 4.9 48.0 6.8 1.6 0.8 4.9 47.3 3.7 0.0 1.2 4.9 9.6 14.7 5.2 21.4 3.0 12.7 14.0 10.7 11.8 2.5 1.1 3.8 5.4 0.3 2.6 28.0 15.7 10.8 37.5 5.1 0.4 0.7 14.8 49.5 2.7 5.4 0.7 0.2 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.3 0.3 0.2 0.1 0.4 0.1 24.8 46.2 62.4 46.1 51.9 4.0 3.3 10.0 1.8 0.0 7.8 17.2 8.1 3.2 2.7 558.3 3.3 21.9 13.7 26.4 13.6 191.9 14.4 10.7 119.2 7.2 23.9 9.2 118.9 3.2 0.1 48.5 1.9 13.5 686.7 12.5 69.9 8.2 6.1 0.0 284.7 8.7 1.7 44.3 43.8 6.6 0.0 87.2 4.2 42.9 13.1 18.5 121.6 20.0 44.7 16.0 25.9 217.9 33.2 9.0 1.8 148.9 59.7 78.0 0.0 488.1 584.6 27.0 13.5 53.8 0.1 11.2 20.3 0.3 41.0 52.0 13.1 29.3 17.7 16.5 17.7 32.4 9.9 1.1 1.1 114.9 17.2 23.7 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.7;pancreas: 54.2" "Cell type enhanced" "Detected in many" "dendritic cells: 134.8;Langerhans cells: 130.7;Macrophages: 90.2;T-cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 43.2;HUVEC TERT2: 28.7;LHCN-M2: 27.6;RT4: 43.1;THP-1: 27.4;TIME: 54.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.48e-4)" 11.7 9.7 0.7 15.1 0.5 85.7 6.3 0.9 1.0 3.1 1.1 20.3 20.6 2.7 1.2 5.6 12.1 11.2 6.4 0.8 0.8 8.5 4.1 18.3 15.4 1.8 2.4 1.2 54.2 1.0 1.1 3.0 1.7 3.0 17.0 0.1 3.5 2.5 3.9 3.8 24.8 5.9 1.7 12.5 19.7 2.9 1.0 19.4 2.8 6.8 9.3 11.6 2.4 3.3 3.7 0.8 0.0 0.1 16.7 19.7 0.1 0.3 1.4 1.0 0.7 0.0 1.1 0.4 0.3 0.0 17.5 2.8 0.2 6.7 1.7 43.2 0.8 0.0 1.5 0.0 15.1 15.2 3.0 2.1 1.0 10.2 4.1 2.3 28.7 14.7 0.0 10.2 27.6 0.0 16.3 7.0 0.1 0.7 6.5 10.7 2.7 1.4 3.9 43.1 0.0 0.0 0.6 1.3 0.1 0.6 6.6 27.4 54.0 5.5 0.0 0.1 1.3 0.1 0.3 2.0 2.4 11.3 1.5 5.3 7.1 14.6 15.8 19.0 9.0 1.8 9.5 9.9 8.1 1.6 5.7 8.1 12.8 3.8 24.7 1.1 8.4 7.3 0.7 0.5 0.9 1.0 0.8 0.8 1.8 2.4 1.7 1.7 1.0 3.3 44.5 12.8 9.0 1.3 46.4 61.2 5.8 16.2 22.8 0.0 9.4 9.1 3.9 0.0 10.2 7.3 0.0 0.2 134.8 45.7 0.0 0.9 3.7 1.6 1.4 18.0 13.1 2.5 2.8 7.7 0.9 30.0 29.6 2.2 10.1 4.6 3.6 0.8 29.5 0.0 3.4 53.8 4.1 49.7 130.7 1.8 0.9 90.2 19.6 3.7 48.8 0.1 57.7 1.5 7.1 2.9 28.1 0.4 38.6 6.7 16.3 0.1 13.0 0.3 0.0 39.1 11.8 7.1 1.0 17.5 30.4 0.3 214.9 0.1 31.4 1.4 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 317.3;Endometrial stromal cells: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" NA NA 12000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 15.0 5.0 9.6 6.7 8.4 2.8 17.5 8.5 8.9 69.5 36.0 9.4 6.5 87.4 87.1 30.1 38.2 24.7 8.8 8.7 10.8 29.3 1.6 33.9 3.9 10.2 11.4 85.3 16.4 13.0 21.1 48.8 8.7 37.9 8.5 6.0 36.7 25.4 0.6 34.6 9.5 38.7 9.0 27.8 12.2 41.7 11.2 30.4 23.0 1.5 6.4 22.3 43.6 8.2 9.1 2.5 83.6 141.6 88.0 89.9 119.4 94.2 145.5 77.0 99.4 77.0 31.0 0.2 74.0 107.3 56.4 99.5 38.0 87.5 49.3 0.7 52.0 8.5 17.1 105.2 132.5 0.3 0.4 129.1 77.4 103.2 32.6 135.8 10.1 35.0 6.2 0.2 36.4 7.0 32.5 12.6 39.1 0.8 7.0 33.3 119.0 0.3 61.0 42.4 48.3 91.6 14.8 1.5 50.0 87.8 51.9 19.5 6.8 84.1 53.1 0.4 51.0 0.5 0.9 3.2 19.1 0.3 14.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.4 0.2 0.7 0.0 13.5 0.0 0.8 9.6 8.4 8.5 8.9 8.7 10.8 10.2 11.4 8.7 9.0 11.2 8.2 3.0 16.0 13.1 10.7 0.8 17.3 19.9 40.4 27.9 4.3 23.5 32.5 1.6 5.7 14.6 12.9 56.3 19.1 6.3 1.7 1.9 21.0 317.3 23.5 84.7 8.7 21.6 4.0 8.7 6.9 2.2 30.0 8.6 25.2 1.3 25.3 2.2 0.0 3.5 0.0 5.3 3.9 42.7 0.0 9.8 48.9 18.3 4.1 16.0 1.0 1.0 20.1 0.0 3.5 1.4 10.5 4.1 18.4 1.4 11.8 0.6 0.6 15.4 2.2 13.1 8.7 27.9 2.8 21.2 13.7 10.4 8.2 3.0 17.7 6.3 11.8 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 60.5 30.1 24.2 43.9 26.6 69.9 50.3 29.2 31.6 40.9 25.9 48.9 18.9 38.6 18.6 38.5 39.6 40.2 39.0 25.1 27.3 36.1 30.9 65.0 27.5 28.5 27.8 34.6 20.1 21.0 21.9 74.7 30.5 26.4 27.7 30.9 23.8 33.2 24.6 36.9 29.7 40.2 26.7 52.7 27.1 30.1 32.7 33.9 31.0 44.5 27.5 46.7 39.6 30.2 72.4 43.5 100.6 51.8 69.1 71.7 54.2 73.3 93.0 56.6 80.0 21.6 109.9 8.6 23.2 86.3 123.6 50.2 34.2 73.4 113.3 21.2 19.2 44.9 44.2 88.4 67.7 25.8 28.8 59.0 80.3 123.2 157.6 101.0 121.6 2.1 54.9 12.2 182.6 49.4 3.6 71.9 81.7 97.6 49.2 15.1 80.6 4.5 97.6 38.5 12.5 66.6 90.4 81.5 73.4 172.2 39.5 93.9 89.3 121.4 73.1 45.0 141.3 12.6 7.4 22.2 71.6 65.9 215.7 3.6 4.1 6.8 3.1 2.8 1.3 2.3 1.1 2.6 3.8 1.0 0.6 3.3 9.5 13.3 5.3 0.3 1.6 2.7 24.2 26.6 29.2 31.6 25.1 27.3 28.5 27.8 30.5 26.7 32.7 30.2 139.3 70.5 56.2 30.0 18.2 68.8 60.0 55.9 23.9 16.7 40.9 26.3 41.3 28.6 46.4 20.2 8.4 40.0 89.0 31.2 3.9 42.1 3.5 43.9 62.4 114.4 12.1 16.6 65.8 39.6 58.7 54.6 21.4 87.2 14.5 21.7 119.2 24.6 50.1 35.3 58.0 21.7 28.5 82.0 121.3 6.7 46.6 96.1 35.6 93.7 54.9 66.9 163.7 70.4 67.3 75.0 21.4 47.0 17.6 62.0 10.9 19.2 23.2 15.2 65.7 127.9 66.8 51.2 71.4 29.8 101.4 72.1 27.3 24.4 23.3 104.8 PWWP3B "FLJ33516, MUM1L1" ENSG00000157502 "PWWP domain containing 3B" Q5H9M0 X 106168305-106208956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "ovary: 189.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.2;Cytotrophoblasts: 1.9;Endothelial cells: 1.7;Fibroblasts: 4.0;Syncytiotrophoblasts: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;HHSteC: 1.6;HSkMC: 2.9;LHCN-M2: 5.5;NTERA-2: 2.1;SuSa: 1.5;T-47d: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000168, HPA020464" Enhanced NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA000168: AB_1079431, HPA020464: AB_1854209" "unprognostic (2.79e-1)" "unprognostic (1.08e-2)" "unprognostic (3.83e-2)" "unprognostic (6.08e-2)" "unprognostic (5.06e-2)" "unprognostic (4.12e-6)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.86e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (8.43e-3)" "unprognostic (2.11e-5)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.53e-2)" 3.5 3.7 4.5 0.0 3.8 0.0 1.0 0.1 7.4 13.7 0.2 0.1 0.0 15.8 9.3 0.3 13.5 1.2 4.3 4.5 12.2 1.4 1.5 0.5 0.0 2.6 8.1 189.9 28.1 0.7 6.1 0.5 5.5 2.4 0.1 0.1 0.2 3.5 10.9 0.2 0.1 3.1 0.5 0.0 1.2 18.0 9.1 0.0 10.3 9.2 0.0 0.3 2.2 3.1 0.0 0.0 2.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.6 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 1.5 1.9 0.0 0.0 0.2 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.8 0.1 7.4 4.5 12.2 2.6 8.1 5.5 0.5 9.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAB27A "GS2, HsT18676, RAB27, RAM" ENSG00000069974 "RAB27A, member RAS oncogene family" P51159 15 55202966-55319113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Exocytosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 119.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 147.1;Intestinal goblet cells: 252.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 261.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 208.7;K-562: 238.0;Karpas-707: 179.4;SK-MEL-30: 188.3;U-937: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001333, CAB034046" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB034046: AB_2176724, HPA001333: AB_1079730" "prognostic favorable (2.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (2.77e-1)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.23e-2)" "unprognostic (4.34e-1)" "unprognostic (7.95e-3)" "unprognostic (4.32e-1)" 17.5 27.8 3.5 40.2 3.9 100.2 13.9 4.4 4.4 12.9 5.6 53.0 30.0 12.8 5.0 20.6 12.3 17.6 7.7 3.4 6.7 19.2 43.6 42.4 46.0 5.8 5.0 8.0 29.2 11.4 31.4 17.6 5.9 61.2 66.1 4.2 18.3 11.8 3.2 12.8 40.9 25.8 5.0 30.8 119.9 10.0 5.9 19.3 30.5 7.0 46.2 37.5 13.9 5.7 23.0 10.0 9.7 11.3 8.3 38.8 9.5 29.4 32.5 19.2 26.4 7.0 15.6 0.9 22.3 16.0 38.9 16.0 15.7 27.0 18.3 84.9 9.7 5.4 37.6 18.1 56.0 208.7 26.5 34.3 44.2 29.0 71.6 80.7 46.9 26.4 238.0 179.4 20.7 27.7 1.5 57.6 3.6 38.9 14.7 32.4 27.3 50.3 28.7 17.7 14.9 7.1 31.4 15.2 188.3 24.3 13.3 162.2 25.3 52.5 20.3 33.1 33.6 72.0 88.2 6.0 70.2 185.1 19.0 261.3 72.4 99.8 59.2 30.1 58.2 8.0 28.6 61.9 39.0 13.4 13.9 37.4 114.9 34.1 24.0 2.1 36.2 48.9 3.5 3.9 4.4 4.4 3.4 6.7 5.8 5.0 5.9 5.0 5.9 5.7 27.5 76.9 147.1 12.7 18.6 14.1 25.7 19.2 6.2 3.0 16.3 18.3 7.4 15.7 50.1 11.0 2.1 6.3 81.0 18.5 13.7 24.6 2.8 10.1 15.6 32.1 74.3 12.8 12.5 87.6 18.7 16.9 93.3 16.7 31.7 8.8 41.7 41.7 15.6 0.0 12.2 252.0 12.2 33.3 15.2 2.2 7.5 31.1 71.2 10.3 71.9 2.4 104.0 10.1 7.1 62.9 15.9 13.9 38.6 32.3 14.6 6.7 31.3 4.4 19.7 9.4 15.8 9.3 4.6 7.1 15.5 7.5 81.4 4.6 18.4 23.4 RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 62.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 140.6;Inhibitory neurons: 509.9;Oligodendrocyte precursor cells: 131.2" "Cancer enhanced" "Detected in some" "glioma: 1.0;pancreatic cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.7;HEL: 2.5;NB-4: 1.6;SCLC-21H: 10.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA003160: AB_1079731, HPA048156: AB_2680291" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (8.73e-3)" "unprognostic (3.40e-2)" "unprognostic (6.90e-2)" "unprognostic (7.58e-2)" "unprognostic (9.52e-4)" "unprognostic (1.51e-3)" "unprognostic (3.70e-5)" "unprognostic (4.70e-2)" "unprognostic (1.05e-1)" "unprognostic (9.65e-2)" "unprognostic (3.61e-3)" 1.1 9.0 19.1 1.2 20.6 0.0 0.7 0.9 32.7 0.1 0.0 0.6 1.6 0.7 0.0 0.2 0.2 0.7 0.1 10.2 62.5 0.0 0.1 0.1 0.2 7.4 12.3 0.3 1.7 0.1 6.8 0.1 31.6 0.0 0.8 6.0 0.1 0.0 0.1 0.0 1.8 0.7 3.9 0.0 0.9 0.1 19.2 0.1 0.1 0.0 0.2 0.6 0.2 3.8 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.6 0.9 32.7 10.2 62.5 7.4 12.3 31.6 3.9 19.2 3.8 8.6 0.0 0.6 10.1 0.4 0.1 0.0 0.0 0.0 28.3 0.3 0.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.9 0.1 20.0 0.0 0.1 12.1 57.6 1.3 140.6 9.6 0.8 0.2 0.0 0.0 2.5 0.0 5.7 1.2 0.1 3.3 509.9 5.5 0.0 0.9 1.1 11.8 0.9 0.1 1.8 6.5 0.0 1.6 0.0 131.2 8.4 3.9 1.2 0.7 0.0 0.0 0.3 0.1 0.0 6.7 13.1 0.5 0.2 2.4 4.1 0.0 0.1 0.0 1.3 0.1 0.3 0.0 RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Astrocytes: 150.8;Microglial cells: 263.3;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 375.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Nucleoplasm "CAB016191: AB_2238209, HPA051869: AB_2681644" "unprognostic (9.10e-3)" "unprognostic (5.45e-2)" "unprognostic (4.92e-1)" "unprognostic (6.65e-2)" "unprognostic (2.38e-2)" "unprognostic (4.85e-2)" "unprognostic (6.42e-3)" "unprognostic (2.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (6.80e-3)" "unprognostic (1.47e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.49e-2)" "unprognostic (6.79e-2)" "unprognostic (8.13e-3)" 3.1 2.3 3.0 2.9 5.7 7.3 5.5 3.8 3.3 5.8 5.8 3.0 1.1 4.4 9.0 3.7 3.9 4.3 1.7 3.4 3.7 2.7 2.1 2.7 4.8 5.7 4.7 6.3 2.1 4.9 2.0 4.1 5.7 2.5 2.6 3.0 13.1 2.3 1.2 4.2 2.4 4.4 4.3 2.6 2.6 1.8 5.0 5.9 2.5 1.2 4.3 3.6 4.5 7.3 15.3 5.9 6.5 3.9 5.9 10.0 4.0 7.6 5.8 8.2 10.5 4.2 20.1 18.6 4.8 4.7 9.4 13.4 4.1 12.1 11.1 8.4 4.2 8.9 5.4 3.3 3.2 7.6 8.6 5.1 9.0 9.4 9.9 3.8 7.4 13.5 7.3 8.4 6.7 11.9 14.9 2.7 3.8 14.6 5.9 16.6 7.7 6.8 6.3 4.3 4.4 2.9 6.0 2.2 13.1 7.6 10.1 6.8 2.0 9.9 9.6 7.8 6.3 4.0 4.4 14.9 5.5 13.1 5.7 17.4 5.7 5.7 8.1 4.8 6.6 14.2 7.6 8.6 6.5 11.8 9.4 8.9 0.7 8.5 4.7 6.4 9.4 4.5 3.0 5.7 3.8 3.3 3.4 3.7 5.7 4.7 5.7 4.3 5.0 7.3 5.1 0.0 1.1 150.8 13.3 6.6 5.1 6.4 5.7 1.8 8.4 5.1 1.6 0.0 4.0 1.8 8.4 5.4 3.5 1.1 3.9 1.9 3.0 5.3 3.7 4.5 4.8 4.6 21.5 1.4 6.7 4.2 3.1 3.6 4.5 6.8 1.8 0.8 6.5 1.7 22.0 3.8 2.0 3.4 3.5 1.9 3.7 4.2 8.8 263.3 6.8 5.8 3.1 157.3 375.2 1.0 0.6 4.5 8.9 2.4 2.7 1.8 8.4 6.0 0.0 3.6 7.0 6.2 3.2 5.6 7.0 4.0 7.0 4.4 1.8 4.6 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RASD2 "MGC:4834, Rhes, TEM2" ENSG00000100302 "RASD family member 2" Q96D21 22 35540831-35553999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 212.9" "Group enriched" "Detected in some" 4 "Intestinal goblet cells: 13.1;Sertoli cells: 46.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 212.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.1;hTERT-RPE1: 9.8;SK-BR-3: 5.6;U-2 OS: 3.1;U-87 MG: 4.0" "Region enriched" "Detected in all" 8 "basal ganglia: 589.6" "Region enriched" "Detected in all" 8 "basal ganglia: 429.3" HPA005839 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA005839: AB_1079745" "unprognostic (1.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.33e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (7.07e-3)" "unprognostic (9.76e-2)" "unprognostic (5.49e-2)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.00e-3)" "prognostic unfavorable (2.22e-5)" "unprognostic (3.75e-2)" "unprognostic (1.61e-1)" "unprognostic (8.42e-3)" "unprognostic (6.22e-2)" 1.8 7.3 30.8 2.5 212.9 3.8 2.3 0.0 30.7 3.1 0.0 28.2 2.3 4.7 15.0 1.9 5.6 2.2 8.6 12.5 9.9 1.5 0.4 3.2 0.4 4.6 12.5 1.2 1.6 1.2 2.1 0.2 6.4 15.2 4.0 0.5 4.0 22.7 15.0 1.6 6.2 7.3 1.8 0.2 3.8 0.7 48.4 0.7 1.2 4.5 1.2 4.3 2.5 9.0 0.1 2.2 0.0 0.4 0.0 0.0 0.0 0.5 0.2 0.8 0.6 0.1 0.4 0.0 0.1 1.9 3.1 0.1 0.1 0.0 0.7 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.1 2.5 1.6 0.2 9.8 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.0 1.5 0.2 1.6 5.6 0.0 0.1 0.4 0.1 0.0 1.3 3.1 0.1 0.7 1.4 0.5 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 212.9 0.0 30.7 12.5 9.9 4.6 12.5 6.4 1.8 48.4 9.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 1.7 2.9 3.3 1.9 0.0 0.2 0.0 0.0 0.0 0.7 3.0 0.0 0.2 0.1 0.1 0.2 2.9 0.0 0.0 3.2 0.2 0.0 3.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.6 13.1 2.0 0.0 0.8 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 1.0 0.7 0.0 2.3 0.7 0.0 0.5 0.1 0.0 0.1 0.2 46.0 0.4 6.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.5 0.3 RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;skeletal muscle: 42.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 186.5;Plasma cells: 64.8;Urothelial cells: 106.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 13.9;memory B-cell: 12.3;naive B-cell: 15.2" "Group enriched" "Detected in many" 16 "B-cells: 15.2;granulocytes: 13.9" "Group enriched" "Detected in many" 7 "Daudi: 88.7;HEL: 92.0;U-266/70: 143.5;U-266/84: 59.1;U-698: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058937 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus" "HPA058937: AB_2683858" "unprognostic (2.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (3.90e-1)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (9.96e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" 7.8 2.9 17.7 15.1 35.2 4.8 5.3 29.8 21.6 3.7 10.2 4.7 7.3 2.5 1.1 2.4 2.5 6.5 34.2 15.1 20.2 6.5 5.5 7.7 27.9 37.4 27.1 1.0 3.4 6.8 2.4 11.0 34.6 1.6 6.6 1.0 6.1 2.0 42.0 1.8 4.7 4.7 25.0 14.8 7.4 0.9 30.7 4.2 6.7 17.6 33.6 6.7 1.2 56.4 0.1 0.0 0.0 0.0 0.0 0.5 0.2 1.2 0.7 4.3 12.4 2.3 0.5 88.7 0.4 0.7 1.0 0.1 0.0 0.0 1.1 9.0 0.8 92.0 0.6 0.0 1.3 0.4 12.4 0.1 0.0 0.1 0.2 1.8 5.3 0.8 0.3 4.8 2.0 0.0 0.7 7.2 0.4 0.5 0.1 0.2 4.1 0.1 1.0 5.3 0.6 0.0 0.0 0.3 4.6 0.1 0.1 0.4 1.7 0.3 0.3 0.4 0.8 143.5 59.1 38.7 0.2 0.4 0.3 13.9 0.0 0.0 0.3 0.0 0.4 12.3 0.6 0.6 0.3 15.2 0.9 0.2 0.0 0.3 0.1 0.0 0.8 1.1 17.7 35.2 29.8 21.6 15.1 20.2 37.4 27.1 34.6 25.0 30.7 56.4 41.4 0.0 5.8 2.0 46.7 5.4 31.2 0.9 0.0 1.6 4.8 2.8 50.8 1.5 3.7 5.5 0.0 0.5 3.6 1.1 11.7 21.1 1.6 10.0 3.9 57.9 0.0 7.4 4.9 54.6 1.3 4.4 3.6 31.0 17.8 2.4 60.7 6.0 44.5 0.0 3.5 0.0 2.0 9.4 26.1 0.8 0.9 29.1 40.9 34.7 13.8 0.2 0.0 2.5 186.5 44.8 0.1 1.9 64.8 37.0 0.2 14.3 3.9 1.3 0.0 5.5 4.1 1.4 2.1 0.4 3.7 0.5 8.1 3.8 0.4 106.4 RAVER2 "FLJ10770, KIAA1579" ENSG00000162437 "Ribonucleoprotein, PTB binding 2" Q9HCJ3 1 64745095-64833232 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Distal enterocytes: 60.1;Inhibitory neurons: 40.4;Oligodendrocyte precursor cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "basophil: 6.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045785 Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA045785: AB_10964058" "unprognostic (8.02e-2)" "unprognostic (5.23e-2)" "unprognostic (4.23e-3)" "unprognostic (2.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.89e-2)" "unprognostic (2.22e-3)" "unprognostic (1.23e-2)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (6.56e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.14e-6)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (1.41e-1)" "unprognostic (5.09e-2)" 4.7 8.2 12.8 4.2 12.1 9.5 8.2 15.0 12.4 7.7 12.6 23.6 24.2 7.8 5.7 9.4 7.5 11.3 12.6 13.3 10.9 7.7 1.6 8.3 2.0 9.7 12.2 6.4 7.3 16.2 12.3 7.3 10.3 12.0 26.8 15.1 15.5 10.3 22.2 6.7 26.1 9.3 10.4 4.3 12.5 2.7 13.3 8.3 6.1 17.7 4.1 6.5 7.4 9.3 16.7 5.1 15.2 16.7 2.7 2.3 4.1 3.6 6.5 7.3 8.2 13.6 7.3 0.1 8.2 3.8 16.6 12.4 15.7 10.9 8.9 0.1 17.3 20.2 13.7 12.2 5.1 27.5 0.2 6.8 9.8 0.5 7.5 16.9 12.2 16.6 4.5 16.3 0.6 6.2 9.2 5.6 18.8 13.1 13.3 31.1 23.9 6.7 8.0 12.3 11.5 25.6 16.4 0.0 16.0 14.3 12.6 4.3 4.6 6.8 10.9 6.8 13.1 12.3 14.9 7.0 4.1 0.1 6.4 6.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 12.8 12.1 15.0 12.4 13.3 10.9 9.7 12.2 10.3 10.4 13.3 9.3 9.2 6.4 13.5 72.8 0.6 8.0 7.0 3.9 8.0 7.1 7.2 6.0 24.4 11.5 8.3 1.8 14.6 0.2 1.1 60.1 0.0 3.4 9.8 5.7 2.5 10.6 18.0 4.2 29.0 5.2 0.3 6.3 11.2 6.5 1.3 7.1 6.8 0.3 0.6 0.0 40.4 30.7 4.1 4.8 3.3 16.8 6.5 2.0 3.6 22.5 0.3 26.1 0.0 40.2 1.8 2.7 20.5 8.2 2.3 6.6 26.9 2.1 6.1 3.7 0.0 6.2 5.5 3.1 3.2 8.5 5.8 0.3 1.5 1.7 27.8 7.3 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RBPMS2 ENSG00000166831 "RNA binding protein, mRNA processing factor 2" Q6ZRY4 15 64739891-64775589 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 300.8;intestine: 147.2" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 215.3" "Cancer enriched" "Detected in all" 4 "testis cancer: 37.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.0;AN3-CA: 55.4;HEL: 86.2;NTERA-2: 76.4;SuSa: 86.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" "unprognostic (1.07e-2)" "unprognostic (6.79e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (4.51e-2)" "unprognostic (6.41e-2)" "unprognostic (5.86e-2)" "unprognostic (2.21e-2)" "unprognostic (4.47e-2)" "prognostic favorable (1.48e-4)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 20.0 4.9 5.2 6.7 6.1 1.6 12.5 2.7 4.7 18.4 14.7 147.2 6.0 53.1 7.5 20.3 30.8 9.9 300.8 3.7 4.3 17.8 13.9 7.6 1.0 3.3 5.0 10.6 2.7 16.5 4.1 7.7 3.0 27.5 8.1 2.0 2.5 45.8 5.6 4.9 30.2 37.6 2.9 4.4 51.9 6.4 12.6 2.5 13.8 4.9 0.6 94.0 14.4 3.2 0.0 6.3 39.0 55.4 0.0 0.0 5.9 1.2 0.2 7.0 1.6 4.9 0.5 0.0 5.2 1.1 6.5 0.0 28.8 0.0 2.6 0.0 9.0 86.2 9.5 9.9 3.7 0.0 0.7 0.1 0.0 4.4 0.0 1.5 0.7 1.9 0.5 0.0 0.5 2.9 0.0 0.3 76.4 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 13.5 8.5 0.1 1.6 86.5 7.9 0.3 0.0 0.0 28.4 3.7 3.7 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 5.2 6.1 2.7 4.7 3.7 4.3 3.3 5.0 3.0 2.9 12.6 3.2 3.1 0.0 0.0 0.0 1.1 0.8 0.3 0.0 0.6 0.3 0.5 0.5 215.3 0.0 0.0 3.7 0.0 0.6 2.0 0.0 9.8 0.4 4.7 0.4 3.4 6.4 0.0 7.4 0.3 1.6 1.1 11.1 5.1 0.7 0.0 0.9 2.9 8.5 0.3 0.0 0.2 0.0 0.0 1.3 1.3 1.0 3.7 10.4 1.8 1.0 0.2 3.3 9.2 0.0 0.0 1.2 0.0 6.4 0.0 1.5 0.0 31.0 0.0 1.7 46.0 1.7 51.0 0.8 14.1 0.3 1.1 3.1 0.7 1.0 0.0 0.2 RCSD1 "CapZIP, MGC21854, MK2S4" ENSG00000198771 "RCSD domain containing 1" Q6JBY9 1 167630093-167708696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 115.5;skeletal muscle: 147.9" "Cell type enhanced" "Detected in many" "B-cells: 258.0;Kupffer cells: 137.5;Macrophages: 80.7;Microglial cells: 78.7;monocytes: 121.6;NK-cells: 142.2;Sertoli cells: 78.9;T-cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 195.2;HDLM-2: 91.0;REH: 224.0;RPMI-8226: 139.7;THP-1: 103.4;U-266/70: 132.0;U-698: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016597, HPA073490" Enhanced Approved "Plasma membrane" NA NA 200000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA016597: AB_2669397, HPA073490: " "unprognostic (2.13e-2)" "unprognostic (7.38e-3)" "unprognostic (6.50e-3)" "unprognostic (1.37e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.97e-4)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (3.65e-1)" "unprognostic (8.48e-2)" "unprognostic (1.01e-1)" "unprognostic (6.33e-2)" "unprognostic (2.53e-3)" "unprognostic (3.19e-1)" "unprognostic (3.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.97e-2)" 14.2 5.8 5.5 42.9 6.1 55.7 11.6 5.8 6.3 5.6 5.9 12.0 8.8 4.6 2.5 8.6 4.0 11.7 25.6 5.2 6.3 5.2 8.0 16.8 88.7 9.9 7.3 2.8 1.5 2.4 2.0 17.5 8.4 3.7 11.9 0.6 4.7 3.9 147.9 2.8 29.3 8.6 6.8 52.4 12.4 3.7 7.7 115.5 6.1 50.6 73.7 14.0 3.4 10.0 0.3 0.0 0.2 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 195.2 0.6 0.2 0.0 0.2 0.0 0.0 0.0 91.0 0.3 1.6 0.1 0.1 0.2 34.4 3.7 0.5 0.3 0.4 0.0 0.0 0.0 76.0 67.8 56.7 25.4 0.0 69.3 49.8 1.7 0.0 0.0 224.0 0.8 139.7 0.0 0.1 0.1 0.1 0.2 0.6 0.1 2.7 0.1 103.4 0.5 0.2 0.6 0.2 0.4 132.0 42.5 132.0 0.1 64.6 0.0 249.3 170.3 271.3 63.5 119.8 76.9 216.4 81.7 80.0 103.4 201.7 68.1 64.7 165.7 130.0 122.7 54.3 129.4 148.9 5.5 6.1 5.8 6.3 5.2 6.3 9.9 7.3 8.4 6.8 7.7 10.0 18.7 3.2 6.7 0.3 258.0 1.1 1.2 0.0 3.4 0.7 6.2 10.7 46.8 0.0 3.1 1.8 0.0 0.5 73.9 0.1 0.0 0.2 0.8 0.4 2.1 18.8 0.0 30.1 4.2 0.0 0.5 12.4 4.1 0.3 13.9 0.2 19.2 1.5 44.2 0.0 0.7 0.0 0.0 137.5 26.9 1.7 0.9 80.7 5.4 78.7 121.6 0.2 142.2 2.0 0.6 0.1 0.0 0.4 55.1 0.8 0.0 0.5 0.0 0.8 78.9 5.8 39.7 0.0 0.3 1.0 1.7 1.2 97.2 0.6 0.1 0.3 RD3L "TDRD9-AS1, TDRD9AS1" ENSG00000227729 "Retinal degeneration 3 like" P0DJH9 14 103940426-103942561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 26 "heart muscle: 23.3;retina: 13.3" "Group enriched" "Detected in some" 9 "Bipolar cells: 78.5;Cardiomyocytes: 40.8;Cone photoreceptor cells: 29.2;Horizontal cells: 26.9;Rod photoreceptor cells: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 10.4" "Low region specificity" "Detected in all" HPA067971 Enhanced Approved "Cell Junctions" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "HPA067971: AB_2685935" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.5 0.0 0.0 40.8 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 REEP3 "C10orf74, Yip2b" ENSG00000165476 "Receptor accessory protein 3" Q6NUK4 10 63521401-63625128 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 346.0;Urothelial cells: 270.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (4.85e-2)" "unprognostic (7.07e-3)" "unprognostic (2.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.50e-3)" "prognostic unfavorable (7.83e-4)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.13e-2)" "unprognostic (9.33e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.89e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (4.06e-2)" 26.5 16.0 10.9 10.3 21.8 2.1 15.9 20.0 12.9 23.5 19.4 16.3 28.3 19.9 16.2 17.1 10.6 15.6 10.5 9.8 15.0 14.0 21.0 17.2 8.8 23.9 20.2 7.4 9.1 29.1 7.0 20.7 23.8 21.6 17.1 6.7 19.8 19.1 6.9 15.5 29.0 25.7 17.8 11.3 13.3 9.2 17.9 6.2 21.0 8.1 9.1 23.6 9.9 35.4 53.6 23.7 21.6 20.7 77.9 76.9 24.3 40.0 66.0 29.9 42.2 33.5 81.2 4.9 14.9 58.5 9.9 61.7 8.7 56.1 52.6 16.3 17.8 11.2 9.7 21.5 50.4 12.5 0.2 65.0 43.2 42.0 63.3 74.2 52.6 6.4 5.5 23.4 54.9 16.3 9.0 19.3 7.5 10.2 50.0 16.0 14.5 10.1 43.1 31.0 6.4 21.7 37.1 36.1 34.7 30.5 35.7 28.6 39.9 28.6 8.6 26.0 31.2 20.0 32.6 7.5 25.8 0.1 30.6 0.1 3.3 2.1 1.6 4.6 3.4 2.0 3.5 2.4 2.9 1.5 1.3 1.9 1.5 1.7 3.0 3.1 5.1 1.6 10.9 21.8 20.0 12.9 9.8 15.0 23.9 20.2 23.8 17.8 17.9 35.4 96.6 28.9 30.4 46.0 25.4 64.5 108.2 46.8 31.9 13.6 76.4 57.1 24.5 34.3 65.9 82.8 27.1 66.7 23.1 113.8 29.4 71.5 346.0 28.9 56.1 64.2 43.0 21.0 96.7 72.1 97.4 56.2 37.8 34.4 9.5 10.7 65.3 71.8 44.2 20.2 37.5 47.0 54.9 38.5 45.4 107.5 105.9 47.6 39.2 65.6 47.1 16.9 13.4 75.9 145.3 156.4 88.3 124.8 47.2 190.8 179.2 46.5 52.1 22.5 98.6 32.0 72.0 133.6 8.8 38.6 73.2 117.5 30.4 42.7 29.4 270.2 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 127.7;Hofbauer cells: 183.4;Kupffer cells: 70.7;Proximal tubular cells: 204.2" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Cell line enhanced" "Detected in many" "EFO-21: 35.5;HMC-1: 121.4;SK-MEL-30: 86.4;U-266/84: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 22.2 19.2 14.6 13.5 18.2 10.9 11.1 16.0 20.6 5.0 12.3 13.8 8.4 3.9 2.5 2.9 5.6 6.2 11.5 14.6 18.8 43.0 5.3 24.6 16.5 18.4 19.8 1.7 1.8 2.1 6.0 10.3 18.0 3.8 4.2 2.2 5.8 2.0 2.2 9.7 13.9 4.7 15.2 67.0 5.9 1.2 19.4 6.2 5.4 0.1 6.3 6.2 4.5 19.6 0.0 0.0 3.3 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 35.5 0.0 0.1 0.0 7.1 0.0 0.0 0.0 1.5 28.2 0.0 2.3 20.4 0.0 121.4 0.8 0.0 0.0 0.0 0.0 0.0 1.0 8.2 10.3 0.0 0.6 7.5 0.3 0.4 0.3 0.0 13.6 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 86.4 3.0 0.3 9.9 1.3 0.0 0.8 0.0 0.1 12.5 74.8 5.0 2.5 13.3 9.8 1.7 0.9 2.7 0.1 0.7 0.1 0.4 0.0 0.0 0.1 0.2 0.4 0.2 2.0 0.1 1.6 0.3 0.0 0.5 14.6 18.2 16.0 20.6 14.6 18.8 18.4 19.8 18.0 15.2 19.4 19.6 1.9 0.0 2.2 7.2 8.0 4.7 1.3 0.3 0.6 2.4 0.4 0.6 1.0 2.8 0.4 9.2 0.0 1.3 2.6 0.4 37.2 1.4 0.1 0.1 0.5 10.7 1.8 3.0 0.2 0.4 6.0 4.5 0.0 0.3 127.7 1.3 52.1 0.8 183.4 15.2 1.7 1.0 0.0 70.7 13.3 0.4 0.3 49.2 28.4 6.5 40.7 10.7 8.2 0.5 6.2 0.5 5.3 0.4 4.0 1.4 12.3 204.2 0.2 0.8 13.1 2.2 4.9 0.1 1.4 0.4 2.0 2.9 7.5 0.7 0.7 0.6 RFLNA "Cfm2, FAM101A, FLJ44614, RefilinA" ENSG00000178882 "Refilin A" Q6ZTI6 12 123973241-124316024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 94.7" "Cell type enriched" "Detected in some" 22 "Pancreatic endocrine cells: 113.9" "Cancer enhanced" "Detected in many" "stomach cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 13.8;HUVEC TERT2: 19.8;LHCN-M2: 34.8;OE19: 37.0;RH-30: 11.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA058911, HPA078021" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Golgi apparatus" "HPA058911: AB_2683853, HPA078021: AB_2732368" "unprognostic (1.71e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (3.15e-2)" "unprognostic (8.78e-4)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.16e-5)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-3)" "unprognostic (1.15e-3)" "unprognostic (1.77e-8)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (6.27e-2)" "unprognostic (1.37e-2)" 3.4 1.1 3.2 2.2 3.8 0.0 1.8 5.7 3.2 10.2 5.4 15.2 13.9 1.7 0.4 0.6 2.9 0.6 0.7 2.7 3.4 2.4 0.1 1.2 0.2 19.1 4.2 2.9 0.3 0.3 2.1 0.6 19.4 4.3 10.4 0.3 2.2 0.3 5.5 1.3 15.2 0.5 3.9 0.1 94.7 0.2 3.7 0.2 0.1 3.2 0.1 0.5 1.3 3.4 0.0 0.0 2.7 0.0 0.0 0.0 3.5 0.0 0.0 0.4 0.4 1.8 1.3 0.0 0.1 4.9 0.2 0.0 2.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.2 0.8 0.0 13.8 0.1 0.8 19.8 2.1 0.0 0.0 34.8 0.0 0.1 0.0 2.9 37.0 0.0 0.0 11.1 0.2 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 3.8 5.7 3.2 2.7 3.4 19.1 4.2 19.4 3.9 3.7 3.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.0 0.1 0.5 0.1 0.0 0.0 0.0 2.6 0.1 0.6 0.0 0.2 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RGS11 ENSG00000076344 "Regulator of G protein signaling 11" O94810 16 268301-275980 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.2;pituitary gland: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Bipolar cells: 69.7;Cone photoreceptor cells: 120.9;Excitatory neurons: 31.9;Inhibitory neurons: 33.6;Oligodendrocytes: 28.0;Rod photoreceptor cells: 67.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;ASC TERT1: 2.2;fHDF/TERT166: 2.0;HHSteC: 3.1;hTERT-RPE1: 2.4;SCLC-21H: 3.0;SH-SY5Y: 2.3;T-47d: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041692, HPA043039" Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA041692: AB_2677619, HPA043039: AB_2678282" "unprognostic (8.39e-2)" "unprognostic (1.97e-1)" "unprognostic (5.46e-2)" "unprognostic (4.55e-3)" "unprognostic (1.46e-1)" "unprognostic (8.50e-2)" "unprognostic (7.48e-2)" "unprognostic (2.02e-1)" "unprognostic (2.93e-1)" "unprognostic (6.56e-2)" "prognostic favorable (1.24e-4)" "unprognostic (1.70e-1)" "unprognostic (1.48e-3)" "unprognostic (6.91e-3)" "unprognostic (2.27e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" 14.7 4.5 13.4 1.0 14.8 0.0 8.4 21.8 40.2 8.8 7.5 21.7 7.1 4.2 0.3 7.4 4.5 0.9 22.3 13.4 11.2 5.4 2.4 9.0 0.4 15.4 14.2 0.8 16.8 4.4 56.4 2.6 15.3 19.2 0.7 8.9 3.8 2.7 2.2 2.5 6.9 1.1 10.2 3.4 15.0 0.8 12.8 0.0 4.2 1.1 0.0 9.2 8.8 14.4 0.0 0.0 0.0 0.0 2.1 2.2 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.8 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.2 0.0 0.0 3.0 2.3 1.2 0.0 0.5 0.0 2.5 0.0 1.6 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 14.8 21.8 40.2 13.4 11.2 15.4 14.2 15.3 10.2 12.8 14.4 1.8 0.0 0.0 31.0 0.1 0.1 0.2 0.1 0.6 69.7 1.0 0.6 7.5 1.5 0.0 0.0 120.9 0.1 0.3 0.9 0.0 0.1 0.0 1.9 5.2 1.8 10.3 0.0 31.9 1.0 0.2 8.6 3.1 3.3 0.0 0.4 6.1 0.0 0.2 10.1 33.6 0.4 2.0 0.0 1.1 0.0 0.9 0.2 1.8 4.7 0.6 3.3 0.0 18.1 28.0 0.4 7.1 1.9 0.0 0.5 5.8 0.0 0.0 67.5 0.0 1.5 7.2 0.5 1.5 0.3 0.6 0.8 0.3 0.1 1.4 0.1 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Sertoli cells: 5114.5;Smooth muscle cells: 1592.3" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1303.0;OE19: 692.4;SH-SY5Y: 4234.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" 138.1 312.4 75.5 29.7 87.2 0.1 58.4 84.2 136.5 160.5 73.1 95.7 64.5 73.7 63.1 71.8 65.5 142.7 238.2 65.9 90.7 88.1 34.1 55.5 33.8 95.6 89.1 19.5 30.6 83.3 45.4 19.9 108.2 75.1 42.9 15.3 27.8 190.0 116.5 21.8 75.8 278.0 68.8 16.7 93.5 40.5 99.6 21.2 164.7 236.8 39.4 136.1 60.5 83.7 0.4 0.0 62.9 8.0 1.3 3.0 2.6 1.1 4.4 2.0 1.3 5.3 1.6 0.5 9.2 1.1 0.7 0.4 0.8 0.8 3.3 3.0 1.0 1.3 0.9 0.1 2.6 0.8 0.7 2.0 1.9 2.1 2.6 14.3 1303.0 0.3 0.2 1.2 4.7 0.0 0.9 2.2 38.7 692.4 1.4 0.4 0.1 3.6 0.7 0.0 5.2 4234.9 0.9 0.0 1.5 185.8 0.0 1.3 5.3 1.0 2.3 0.9 2.0 1.5 1.2 0.4 1.4 0.2 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.2 0.1 0.2 0.4 0.4 0.1 0.2 0.1 0.0 0.2 0.1 75.5 87.2 84.2 136.5 65.9 90.7 95.6 89.1 108.2 68.8 99.6 83.7 458.3 3.2 5.6 61.4 1.7 17.1 6.0 1.0 0.6 1.8 9.8 12.1 0.0 0.0 7.3 1.8 4.2 1.5 2.4 0.3 1.9 1.0 32.7 3.4 11.6 353.7 0.0 0.0 24.4 1.1 0.8 43.0 223.3 8.1 1.3 0.9 0.0 0.0 1.2 0.0 60.5 0.2 0.0 0.0 26.3 17.0 6.8 11.9 23.2 80.6 0.6 2.6 0.0 25.1 69.7 3.9 0.2 2.6 0.4 12.7 0.2 2.5 5.9 5.8 5114.5 44.9 1592.3 5.7 1.7 5.2 12.6 1.2 5.8 5.5 0.2 7.0 RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal enterocytes: 62.0;Proximal tubular cells: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported Nucleoplasm No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA039094: AB_10671037, HPA039095: AB_2676345, HPA061531: AB_2684554" "unprognostic (7.10e-2)" "unprognostic (4.26e-2)" "unprognostic (2.78e-2)" "unprognostic (3.55e-2)" "unprognostic (2.56e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.47e-2)" "unprognostic (2.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 6.8 25.4 17.0 7.1 17.4 7.1 7.7 16.0 20.2 8.7 14.6 9.7 13.1 8.1 6.4 14.3 14.0 5.9 15.0 17.5 15.7 15.9 29.6 6.9 11.1 15.1 15.3 10.6 10.6 9.5 12.6 4.7 15.2 10.1 5.9 4.4 13.7 8.3 31.7 10.8 14.2 4.6 12.6 9.5 8.8 7.4 16.9 9.7 10.4 27.2 8.2 8.5 8.1 15.3 27.0 34.3 8.7 23.0 11.5 8.8 15.6 17.2 35.3 24.9 19.8 40.7 13.0 50.8 26.0 14.6 21.4 20.0 20.0 22.3 14.4 31.3 28.4 17.4 16.6 26.6 18.7 23.4 14.0 13.6 20.2 24.6 13.8 34.5 20.7 24.7 34.0 9.2 14.9 38.6 26.1 63.1 29.2 22.9 41.8 23.2 9.3 43.2 20.3 37.8 28.9 16.6 21.7 45.2 38.2 10.6 38.2 35.5 13.7 15.7 22.3 18.2 24.7 31.6 28.6 56.0 23.4 19.4 22.5 43.7 14.6 9.9 15.3 6.6 15.3 11.0 13.5 13.9 16.5 11.8 13.2 14.6 0.3 20.7 8.6 22.5 16.1 13.5 17.0 17.4 16.0 20.2 17.5 15.7 15.1 15.3 15.2 12.6 16.9 15.3 8.1 0.0 11.3 2.9 11.1 6.4 7.1 14.0 7.4 7.4 14.7 14.7 6.6 12.8 9.1 14.7 4.2 19.3 9.8 17.0 49.0 19.2 10.8 16.7 7.3 9.3 11.4 8.8 6.5 16.4 16.9 7.0 8.2 7.3 0.0 8.7 8.6 37.5 14.2 15.2 6.7 12.5 8.2 7.8 2.4 29.6 9.9 6.3 5.4 2.8 5.9 11.0 19.6 2.0 3.7 15.2 12.9 8.2 14.7 10.1 62.0 51.9 17.1 6.0 6.6 7.7 7.5 4.5 7.8 13.8 6.5 10.1 9.0 17.2 12.7 7.5 RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 490.2;Glandular and luminal cells: 761.3;Hofbauer cells: 382.2;Kupffer cells: 484.7;Macrophages: 418.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 497.9" "HPA029013, HPA066509" Approved "Secreted to blood" NA NA 15000000 "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA029013: AB_10602922, HPA066509: AB_2685682" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.70e-14)" "unprognostic (5.03e-2)" "unprognostic (7.34e-2)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" 34.9 35.0 50.1 68.6 50.4 124.3 50.2 52.2 65.9 161.5 52.3 74.0 57.6 49.1 140.7 24.8 134.6 69.6 19.8 49.5 53.5 31.2 52.4 47.2 117.4 68.2 54.3 36.2 144.7 40.7 26.3 43.5 66.2 51.9 89.9 8.3 112.8 94.1 7.3 25.4 65.4 27.8 61.9 195.1 72.9 13.3 59.1 43.8 76.7 12.1 86.9 54.9 32.2 79.8 12.8 14.2 12.6 37.8 57.0 40.6 8.4 15.8 21.2 7.3 7.4 33.7 19.9 11.1 149.8 41.3 16.7 41.0 20.8 18.6 4.3 15.9 35.1 10.2 20.6 84.6 19.1 152.7 37.3 23.9 33.6 4.3 2.7 30.4 10.1 21.7 20.9 94.5 10.9 44.9 12.6 109.5 6.4 140.0 13.0 25.0 16.6 131.7 136.3 9.9 4.4 28.7 32.0 100.4 8.3 22.3 13.1 497.9 19.3 14.9 9.8 43.7 13.5 15.0 19.5 1.4 32.3 149.2 10.3 116.9 185.6 674.8 29.1 277.0 53.4 136.7 159.9 72.3 226.4 119.6 128.4 41.4 438.9 30.7 368.8 369.3 90.8 179.8 50.1 50.4 52.2 65.9 49.5 53.5 68.2 54.3 66.2 61.9 59.1 79.8 21.8 19.2 29.3 10.1 270.1 43.3 116.4 45.1 72.3 10.5 97.0 95.1 9.5 47.1 28.0 38.6 0.0 63.4 286.8 133.7 23.5 59.2 10.3 490.2 78.9 44.9 75.4 27.6 13.6 27.4 58.8 45.8 80.0 761.3 71.7 38.6 19.2 20.0 382.2 13.5 37.1 204.0 24.4 484.7 187.7 11.3 35.4 418.2 58.7 113.4 146.1 24.4 64.9 14.6 1.7 74.1 324.8 29.3 158.6 61.2 178.5 19.6 19.0 7.1 26.3 31.9 18.6 10.0 23.1 58.3 34.5 27.8 149.2 15.3 193.0 103.9 RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Bipolar cells: 6.6;Excitatory neurons: 19.6;Inhibitory neurons: 11.6;Muller glia cells: 7.6;Oligodendrocyte precursor cells: 13.6;Sertoli cells: 6.6" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.2;fHDF/TERT166: 6.2;SCLC-21H: 6.0;SH-SY5Y: 10.6;U-87 MG: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" 2.2 5.4 20.2 1.5 21.9 0.1 1.9 33.8 25.0 3.2 7.2 9.4 1.8 3.0 4.5 1.7 3.2 2.8 3.6 24.7 16.8 3.9 1.0 2.8 0.7 12.7 14.2 2.4 1.3 0.0 5.5 0.5 14.0 12.3 2.8 1.5 1.2 2.0 1.3 1.9 6.9 2.2 12.9 3.0 2.5 2.3 16.6 0.2 2.2 1.3 0.2 8.4 3.2 23.2 0.0 0.0 0.1 0.4 1.4 5.2 0.2 0.3 1.2 0.1 0.0 0.2 0.0 0.0 0.1 6.2 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 4.2 0.0 0.1 2.1 0.2 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.4 0.1 0.2 0.2 0.0 0.0 6.0 10.6 0.1 0.0 0.0 1.4 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.1 0.0 0.0 34.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 21.9 33.8 25.0 24.7 16.8 12.7 14.2 14.0 12.9 16.6 23.2 1.1 0.0 0.0 8.1 0.0 1.0 0.0 0.2 0.0 6.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 19.6 0.0 0.0 3.3 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 11.6 0.2 0.0 0.6 0.4 0.2 0.0 0.3 0.0 4.7 0.1 7.6 1.0 13.6 3.3 0.0 1.4 3.8 0.0 0.2 0.5 0.0 0.1 0.7 6.6 1.4 1.5 1.7 0.7 0.3 1.0 0.3 0.2 0.0 0.1 0.1 RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468870 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 634.4;Langerhans cells: 296.9;Suprabasal keratinocytes: 1501.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 71.9" "Group enriched" "Detected in many" 9 "dendritic cells: 18.4;granulocytes: 36.7;monocytes: 71.9" "Cell line enhanced" "Detected in many" "Daudi: 192.8;hTCEpi: 59.1;HUVEC TERT2: 55.6;TIME: 56.1;U-698: 160.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: AB_2682391, HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" 9.4 2.0 7.4 15.6 7.4 24.0 29.1 7.9 9.0 9.5 9.1 4.2 1.8 5.7 4.7 8.4 11.8 6.2 8.1 6.4 7.7 14.0 15.5 19.4 11.3 11.8 11.9 1.6 3.2 2.9 1.7 15.1 9.4 13.1 2.8 5.0 16.9 7.3 56.9 21.1 3.3 6.2 8.9 13.1 5.7 2.3 10.5 5.1 40.9 14.1 12.9 9.4 7.1 8.7 4.6 1.0 0.4 0.0 0.3 2.0 9.8 5.3 5.7 11.0 11.8 0.1 0.4 192.8 50.7 2.3 0.6 16.3 0.1 16.0 15.5 0.9 1.4 0.2 0.2 4.2 0.2 0.2 0.2 2.7 59.1 4.3 13.2 4.9 55.6 4.3 0.1 0.0 2.7 2.0 1.5 0.0 1.6 0.6 1.1 0.7 1.7 11.8 33.2 10.6 1.9 0.2 1.2 23.9 18.5 1.5 28.2 0.5 56.1 8.6 1.9 0.8 1.2 0.0 0.1 160.6 1.0 0.4 0.7 0.4 20.7 12.9 0.5 38.9 1.6 4.6 0.8 0.6 13.3 3.6 1.6 1.0 36.7 0.6 71.9 18.4 0.5 7.1 7.4 7.4 7.9 9.0 6.4 7.7 11.8 11.9 9.4 8.9 10.5 8.7 28.8 44.8 15.0 34.9 21.7 634.4 48.8 86.0 14.8 0.9 35.7 26.3 12.8 17.2 48.3 38.6 2.1 14.1 9.8 2.2 19.6 8.6 2.1 49.0 5.8 34.6 1.2 3.8 2.3 8.9 3.7 7.8 10.7 58.5 3.8 0.1 47.2 21.9 15.0 0.0 99.0 1.8 14.2 109.4 296.9 1.8 1.2 171.7 60.5 92.8 54.1 17.9 1.0 3.5 2.5 5.2 3.6 3.0 3.4 112.3 0.9 20.6 36.7 1.2 0.0 9.0 7.8 2.2 3.2 30.0 1501.1 1.5 4.9 0.1 2.3 42.6 RNF212 "FLJ38841, LOC285498" ENSG00000178222 "Ring finger protein 212" Q495C1 4 1056250-1113564 "Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 9.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 62.6;Spermatocytes: 52.3;Spermatogonia: 42.4" "Cancer enhanced" "Detected in many" "cervical cancer: 5.3;ovarian cancer: 5.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "A-431: 11.8;HeLa: 39.4;JURKAT: 18.0;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA057527 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA057527: AB_2683457" "unprognostic (2.75e-2)" "prognostic favorable (1.39e-4)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (1.10e-2)" "unprognostic (2.57e-2)" "unprognostic (4.49e-2)" "unprognostic (1.33e-1)" "unprognostic (2.09e-2)" "unprognostic (2.68e-1)" "unprognostic (1.12e-2)" "unprognostic (3.45e-2)" "unprognostic (7.65e-2)" "unprognostic (8.36e-2)" "unprognostic (1.60e-1)" "unprognostic (5.52e-2)" "unprognostic (1.05e-1)" 1.5 1.2 1.0 0.7 1.5 2.0 1.6 4.4 1.1 1.5 1.1 1.7 0.4 1.0 1.0 1.2 2.1 0.8 0.7 1.0 0.8 4.5 0.2 1.4 1.0 0.8 0.6 5.0 9.2 1.3 7.4 0.3 0.9 1.8 0.6 1.3 1.7 0.5 0.5 1.9 1.1 0.8 0.9 1.1 1.0 3.0 0.8 0.8 3.2 0.6 0.7 0.9 1.8 1.0 11.8 0.7 0.1 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 0.0 5.3 0.1 0.0 2.9 0.0 3.1 0.0 0.0 0.0 18.0 0.1 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 3.8 0.0 22.6 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.5 0.2 1.2 0.2 0.4 0.6 1.1 0.3 0.0 0.1 0.0 0.1 0.2 0.3 1.0 1.5 4.4 1.1 1.0 0.8 0.8 0.6 0.9 0.9 0.8 1.0 1.1 3.2 6.9 1.3 1.3 2.8 5.6 1.5 13.6 3.0 3.9 4.8 0.6 1.5 6.8 0.0 2.1 0.0 1.1 0.5 62.6 3.8 3.9 0.5 2.5 0.8 4.9 0.0 4.7 0.9 0.2 11.7 1.1 1.1 4.5 1.9 0.4 0.0 0.6 0.0 1.7 2.8 0.0 0.8 1.8 7.5 8.4 1.8 0.0 2.8 0.9 5.1 2.1 0.0 4.4 0.8 1.6 0.7 0.8 4.6 0.7 8.9 2.2 6.4 0.0 6.8 1.7 52.3 42.4 4.5 3.1 0.3 1.8 2.1 1.2 4.5 ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3438.7;Inhibitory neurons: 4706.0" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 29.8;HEL: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" 0.7 2.4 10.1 0.5 13.6 0.0 0.6 0.0 14.2 2.4 0.0 0.8 0.5 2.1 0.4 4.8 0.1 2.3 0.6 10.4 1.7 1.8 1.2 10.0 1.5 14.8 13.1 7.0 1.6 2.8 1.5 5.2 14.3 1.2 0.4 15.4 1.6 5.7 0.1 2.3 0.7 1.4 16.7 2.9 0.7 3.7 4.9 9.3 0.1 0.4 2.2 1.2 1.7 8.1 0.0 0.0 2.2 0.0 7.5 8.1 0.1 0.3 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 9.8 83.9 1.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 5.1 9.1 0.0 0.0 1.1 5.1 12.2 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 13.6 0.0 14.2 10.4 1.7 14.8 13.1 14.3 16.7 4.9 8.1 0.7 0.0 0.5 164.6 0.0 1.8 2.0 0.4 19.4 30.8 0.2 1.0 2.4 1.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 1.0 1.7 1.1 0.0 0.0 3438.7 0.0 0.1 10.6 0.0 3.2 0.0 2.3 3.3 0.7 0.1 52.2 4706.0 3.0 0.0 0.0 2.8 3.4 3.1 0.1 0.0 54.4 0.0 2.0 0.0 63.3 52.4 0.2 0.0 6.0 0.0 0.8 0.3 0.1 0.1 5.6 0.0 0.1 0.9 2.9 1.1 15.7 1.1 0.1 0.2 40.5 0.5 0.2 RPL3L ENSG00000140986 "Ribosomal protein L3 like" Q92901 16 1943974-1957606 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 943.6;tongue: 422.7" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 134.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049136 Enhanced Approved "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA049136: AB_2680648" "unprognostic (2.53e-1)" "unprognostic (2.63e-2)" "unprognostic (9.27e-4)" "unprognostic (6.38e-4)" "unprognostic (4.36e-2)" "unprognostic (3.48e-3)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.19e-2)" "unprognostic (2.00e-1)" "unprognostic (2.46e-2)" "unprognostic (4.53e-3)" "unprognostic (3.32e-1)" "unprognostic (4.24e-1)" "unprognostic (8.32e-3)" "unprognostic (4.60e-2)" 0.3 0.4 0.9 0.2 0.6 1.7 1.4 1.7 0.8 0.0 1.0 0.2 0.6 0.3 0.4 8.5 0.1 0.5 174.0 0.5 0.4 0.4 0.3 0.2 0.4 0.1 0.0 0.3 11.5 0.0 0.1 0.2 0.1 4.2 0.0 1.2 6.9 0.1 943.6 0.7 0.5 0.0 0.0 0.4 0.2 6.4 0.1 0.1 0.4 422.7 0.1 0.2 0.1 1.0 1.1 1.2 0.3 1.1 0.0 0.0 0.7 0.5 0.0 0.0 0.0 4.0 2.1 0.6 0.7 0.0 1.0 1.1 0.1 0.1 0.0 0.5 0.6 0.4 0.9 1.4 0.0 0.3 0.4 0.1 0.1 0.1 0.1 0.7 0.0 0.7 0.4 2.8 0.0 0.6 0.8 1.0 0.6 1.2 2.5 0.4 0.3 0.9 0.1 0.4 1.6 0.5 0.5 1.4 0.6 0.7 0.7 0.6 0.6 0.6 1.4 0.8 0.4 1.2 0.6 0.5 0.8 0.2 0.2 0.5 0.2 0.3 0.3 0.3 0.2 0.4 0.2 0.3 0.1 0.4 0.3 0.3 1.2 0.2 0.3 0.4 0.1 0.1 0.9 0.6 1.7 0.8 0.5 0.4 0.1 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.2 0.0 0.0 0.1 0.6 134.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 7.9 0.0 0.1 1.3 0.0 5.3 0.1 0.0 0.2 2.9 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 23.7 2.2 0.7 2.4 0.0 0.4 0.0 0.2 0.1 0.1 0.5 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954418-74956772 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 95.1;Hofbauer cells: 77.0;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 25.8" "Group enriched" "Detected in many" 5 "dendritic cells: 25.8;monocytes: 10.1" "Cell line enhanced" "Detected in many" "HHSteC: 46.0;SCLC-21H: 42.9;SK-MEL-30: 67.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory bulb: 23.0" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 6.0 13.2 7.4 2.7 8.9 0.4 4.5 14.6 8.5 7.1 6.5 7.9 7.2 3.7 1.8 6.9 4.4 4.5 5.5 4.9 10.8 5.1 3.1 5.8 3.9 16.5 12.7 15.4 7.6 23.0 5.2 7.2 16.4 4.2 4.8 12.8 4.6 1.7 1.4 4.9 5.7 2.5 10.8 10.8 7.1 3.0 12.8 2.4 8.9 1.5 3.4 7.7 5.4 12.7 23.6 17.5 4.4 0.1 1.5 0.9 7.4 4.3 5.2 1.3 1.2 24.1 21.0 0.0 19.4 4.4 1.2 6.9 13.7 0.8 0.3 8.9 0.7 0.1 19.9 0.5 46.0 0.0 13.3 5.9 0.6 8.5 0.0 0.9 20.4 5.5 16.1 0.0 4.6 9.1 3.8 6.3 20.8 40.9 7.0 0.1 0.0 15.8 4.2 0.4 42.9 32.1 32.6 28.8 67.4 2.2 5.7 18.7 4.6 0.0 1.4 3.8 0.2 0.4 0.1 0.1 2.3 36.6 25.1 0.0 5.2 0.0 2.3 10.1 1.3 3.4 1.5 1.8 5.1 3.7 3.8 3.0 0.4 0.5 7.7 25.8 0.7 2.5 7.4 8.9 14.6 8.5 4.9 10.8 16.5 12.7 16.4 10.8 12.8 12.7 5.3 3.2 1.1 0.3 4.9 11.0 7.5 9.1 11.4 95.1 11.8 9.9 1.6 14.3 6.4 9.2 4.2 2.3 17.0 24.4 13.7 13.7 0.3 1.6 4.7 8.9 10.2 0.8 0.7 19.3 4.3 23.9 14.8 3.6 0.0 3.4 31.8 1.6 77.0 21.9 10.0 12.5 14.2 14.8 8.6 2.6 39.4 9.3 14.2 1.0 16.1 13.4 4.1 0.0 6.3 13.8 20.5 30.1 8.2 19.1 27.5 16.6 1.3 72.3 13.1 4.3 10.4 1.4 6.5 18.2 11.5 2.3 2.1 26.6 20.7 10.5 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84188199 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.3;Inhibitory neurons: 70.7;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.1;PC-3: 7.9;RH-30: 9.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.4 2.0 2.6 0.5 3.1 0.1 1.7 3.2 3.0 2.0 2.6 2.9 1.2 1.7 3.1 0.8 2.2 1.1 0.6 2.7 3.4 5.7 0.6 0.6 0.2 2.7 2.4 2.6 0.9 7.0 5.8 0.3 2.2 2.8 2.3 7.0 1.7 2.7 1.6 2.0 1.3 1.0 1.5 0.4 1.7 1.5 2.4 1.0 8.1 0.4 0.3 1.3 1.4 2.0 0.0 2.4 2.6 0.0 2.4 2.2 0.0 5.2 2.7 2.3 1.9 1.9 2.0 0.0 0.0 2.6 0.0 0.1 6.4 4.6 5.1 0.0 3.5 0.0 0.1 0.0 2.7 0.0 0.0 1.4 0.0 0.0 2.4 3.0 0.6 0.0 0.0 0.1 2.0 0.0 1.1 0.1 8.1 0.0 7.9 0.0 9.9 0.0 0.5 5.4 0.0 9.4 0.0 3.4 0.0 3.8 1.4 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 2.6 3.1 3.2 3.0 2.7 3.4 2.7 2.4 2.2 1.5 2.4 2.0 0.3 9.6 2.7 6.2 0.7 0.3 5.3 0.3 3.4 21.1 3.6 3.4 2.6 12.8 1.9 18.4 25.0 2.6 0.1 6.7 1.9 0.5 0.7 1.9 1.2 1.2 25.0 2.7 75.3 1.2 0.7 2.2 2.0 0.9 0.0 21.8 1.1 1.3 0.2 1.7 70.7 3.6 0.0 0.0 0.0 0.4 4.4 0.5 0.0 3.7 0.1 2.1 1.0 31.2 5.8 1.3 3.4 6.0 0.0 9.2 1.8 4.3 3.7 18.2 0.0 4.9 1.5 8.4 6.2 2.5 0.4 2.3 0.9 2.0 6.5 5.2 RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 149.6;liver: 124.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 4 "dendritic cells: 6.6;NK-cells: 2.3" "Cell line enhanced" "Detected in many" "Hep G2: 96.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA030259: AB_10601484" "unprognostic (4.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-3)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (2.57e-2)" "unprognostic (9.43e-3)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.96e-2)" "unprognostic (7.15e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.23e-3)" 9.8 8.3 69.5 5.0 104.1 0.6 11.3 85.4 84.6 13.5 51.9 20.3 31.8 8.7 3.5 20.8 12.7 14.2 17.3 72.0 84.3 54.4 124.7 10.3 3.1 100.4 95.5 7.7 30.8 20.7 14.7 11.8 95.7 19.1 12.6 1.9 26.0 9.5 12.8 32.0 25.3 6.3 73.4 5.2 15.3 3.3 93.5 6.3 19.5 7.5 5.3 8.3 16.6 149.6 50.4 15.5 19.5 56.3 11.8 13.7 82.1 7.6 9.9 11.0 8.0 76.3 26.8 0.3 21.2 7.4 13.6 67.2 7.3 48.6 5.3 9.9 31.3 12.0 2.8 96.7 7.2 0.0 0.1 8.4 37.7 9.5 30.0 20.2 5.5 0.7 6.2 0.3 16.5 35.8 1.9 10.1 20.9 70.9 30.3 11.1 60.6 7.6 52.4 0.3 19.0 18.8 20.7 79.3 45.2 17.5 44.6 4.4 0.6 20.5 14.0 9.3 10.6 4.8 3.7 1.8 19.6 0.1 19.5 0.0 0.0 0.0 0.2 0.0 0.2 0.7 0.1 0.2 0.6 1.0 0.0 0.1 0.0 2.3 0.0 6.6 0.0 0.4 69.5 104.1 85.4 84.6 72.0 84.3 100.4 95.5 95.7 73.4 93.5 149.6 4.3 9.6 11.8 4.9 2.0 20.0 22.1 37.2 19.4 0.1 14.4 12.2 3.1 28.6 18.3 11.0 2.1 46.7 4.5 21.7 21.5 43.0 0.7 12.6 6.1 8.8 30.7 1.3 0.5 20.1 8.3 8.9 15.8 26.0 1.3 4.9 5.3 40.1 10.1 0.0 0.9 20.1 18.3 2.2 3.8 1.5 12.8 1.1 28.4 3.7 0.7 6.9 5.2 34.7 48.2 30.5 31.0 8.6 1.4 35.4 44.7 54.7 5.8 0.4 6.6 36.9 3.9 1.1 5.6 12.9 21.6 33.4 2.5 3.1 30.5 15.6 RTL8C "CXX1, FAM127A, Mar8, MAR8C, Mart8, SIRH5" ENSG00000134590 "Retrotransposon Gag like 8C" A6ZKI3 X 135032355-135033546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 111.8;Distal tubular cells: 140.8;Endometrial stromal cells: 92.5;Extravillous trophoblasts: 99.6;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.89e-2)" "unprognostic (2.50e-2)" "unprognostic (3.94e-3)" "prognostic unfavorable (2.69e-4)" "unprognostic (3.64e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.99e-4)" "unprognostic (8.76e-2)" "unprognostic (6.77e-2)" "unprognostic (5.65e-2)" "prognostic favorable (1.97e-4)" "unprognostic (2.06e-1)" "unprognostic (6.45e-2)" "unprognostic (9.02e-3)" "unprognostic (2.21e-1)" "unprognostic (6.13e-2)" "unprognostic (6.09e-3)" 175.1 204.4 190.3 37.2 206.9 10.2 141.2 188.4 305.2 183.7 117.4 197.8 22.9 205.6 27.2 201.2 166.5 45.0 453.7 200.9 215.0 174.4 77.5 134.3 20.2 213.2 221.6 193.7 61.6 38.3 228.1 60.4 216.3 183.9 20.2 34.4 101.2 81.5 239.2 99.1 93.2 95.9 174.5 82.9 121.2 57.9 202.0 19.8 117.6 187.9 15.5 164.3 169.1 192.6 68.6 79.1 78.0 113.1 270.2 310.9 55.1 178.6 137.7 101.9 140.0 65.9 25.5 0.0 218.1 237.1 120.2 69.7 72.1 71.5 38.1 45.9 114.6 18.0 139.2 37.4 160.0 0.0 35.4 337.8 93.6 115.5 29.4 132.6 123.2 0.0 29.1 0.2 172.8 130.8 0.3 50.0 32.3 29.3 147.1 0.0 82.6 0.7 107.9 31.4 58.2 138.8 61.6 46.0 86.6 39.7 29.7 31.5 150.1 141.0 51.4 344.4 131.9 21.7 17.8 0.4 196.0 17.9 76.9 28.1 73.4 67.6 44.1 90.7 34.1 23.2 35.8 45.9 53.4 33.9 41.7 47.5 18.2 49.2 77.9 58.0 39.8 41.8 190.3 206.9 188.4 305.2 200.9 215.0 213.2 221.6 216.3 174.5 202.0 192.6 48.1 38.5 23.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 33.1 31.1 0.0 0.0 16.7 36.8 0.0 111.8 7.9 0.0 140.8 42.3 0.0 27.5 92.5 24.3 0.0 0.0 0.0 26.3 99.6 58.6 0.0 47.6 18.9 35.3 0.0 0.0 63.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 27.9 0.0 0.0 0.0 0.0 39.3 0.0 0.0 1.9 0.0 0.0 67.3 10.2 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 94.0 5.2 45.9 0.0 0.0 RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Astrocytes: 13.4;Cone photoreceptor cells: 25.0;Melanocytes: 28.4;Muller glia cells: 16.8;Sertoli cells: 13.1;Skeletal myocytes: 35.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 39.4" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" 2.4 3.2 14.6 0.4 16.6 0.0 1.0 11.7 17.4 3.0 11.7 4.1 0.7 1.1 0.7 1.0 2.8 0.6 5.3 12.4 21.5 0.2 0.3 2.8 0.3 25.6 14.8 1.0 2.1 0.1 29.9 0.7 22.2 1.1 2.0 24.3 1.2 1.4 49.7 2.3 1.6 1.2 13.6 0.4 1.4 1.0 32.1 0.1 0.7 7.6 0.0 1.6 2.1 15.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 16.6 11.7 17.4 12.4 21.5 25.6 14.8 22.2 13.6 32.1 15.6 0.9 0.0 0.0 13.4 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 2.8 5.0 0.0 28.4 0.0 0.0 16.8 0.0 1.0 1.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.5 13.1 35.9 3.4 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 SAMD14 FLJ36890 ENSG00000167100 "Sterile alpha motif domain containing 14" Q8IZD0 17 50110040-50130160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 56.1" "Cancer enhanced" "Detected in some" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 12.7;HEL: 8.6;HMC-1: 28.0;SH-SY5Y: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051916 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 65: Brain - Ion transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nucleoli fibrillar center" "HPA051916: AB_2681662" "unprognostic (2.33e-2)" "unprognostic (6.05e-2)" "unprognostic (2.85e-1)" "unprognostic (2.10e-1)" "unprognostic (3.24e-1)" "unprognostic (2.31e-1)" "unprognostic (8.84e-3)" "unprognostic (6.77e-2)" "unprognostic (1.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.61e-2)" "unprognostic (3.06e-2)" "unprognostic (1.23e-3)" "unprognostic (1.93e-2)" "unprognostic (4.00e-2)" "unprognostic (9.01e-2)" "unprognostic (7.48e-4)" 0.9 1.4 14.9 0.8 14.0 0.3 0.5 19.4 15.4 1.6 0.0 1.0 0.2 3.1 0.8 0.5 0.5 0.3 1.2 15.3 11.0 3.1 0.8 6.0 0.3 9.4 8.8 1.3 0.2 0.7 3.4 0.7 8.5 3.0 0.1 1.3 0.1 0.7 1.4 0.3 0.9 0.4 6.0 1.7 1.1 2.1 11.2 0.1 0.9 0.5 0.5 1.8 1.1 10.1 0.0 0.2 4.2 0.0 1.1 0.3 0.0 3.0 1.1 0.1 0.0 0.6 0.0 0.1 4.1 1.3 0.0 0.1 0.3 0.0 0.1 12.7 0.1 8.6 0.3 0.0 0.7 0.0 28.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.3 0.3 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 4.4 12.9 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.6 1.6 0.3 0.1 0.2 0.0 0.1 2.2 0.1 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 14.0 19.4 15.4 15.3 11.0 9.4 8.8 8.5 6.0 11.2 10.1 0.6 0.0 0.5 6.2 0.0 0.4 0.1 0.2 0.6 56.1 0.2 0.3 1.1 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.2 3.1 0.0 1.4 6.1 12.7 2.7 8.3 0.4 0.2 2.3 0.5 0.1 2.5 0.1 8.2 0.3 0.1 11.8 7.2 0.3 0.0 0.6 1.0 2.2 1.5 5.7 0.0 1.0 2.0 2.2 0.0 2.5 0.4 0.2 0.1 3.4 0.2 0.0 0.3 1.1 0.0 4.6 0.0 0.1 2.8 1.5 1.1 0.2 0.1 0.4 0.2 0.7 0.1 0.1 SAMD4A "DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA" ENSG00000020577 "Sterile alpha motif domain containing 4A" Q9UPU9 14 54566117-54793315 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 94.3;testis: 107.9" "Group enriched" "Detected in many" 4 "Early spermatids: 1176.0;Late spermatids: 2275.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043061, HPA065309" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" Cytosol "HPA043061: AB_2678299, HPA065309: AB_2685462" "unprognostic (1.46e-1)" "unprognostic (8.10e-3)" "unprognostic (9.66e-3)" "unprognostic (1.18e-4)" "unprognostic (2.79e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (1.09e-2)" "unprognostic (2.83e-2)" "unprognostic (8.27e-2)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" 16.6 4.2 27.4 8.9 33.1 0.4 13.1 42.3 24.9 13.0 14.1 37.6 3.2 26.1 4.0 6.7 12.0 6.0 47.8 22.6 40.3 12.4 16.6 21.2 4.6 79.0 46.2 4.5 6.2 3.8 6.1 9.2 69.4 14.5 4.8 2.6 7.0 9.4 94.3 8.9 10.4 17.1 64.1 7.1 10.9 107.9 41.8 1.1 7.0 39.3 3.1 17.7 12.8 60.8 32.9 2.9 6.7 3.4 14.0 21.3 11.7 27.4 41.4 22.3 22.0 36.8 7.8 1.8 14.0 41.7 8.8 22.6 6.6 14.2 32.8 16.5 2.8 0.0 4.0 7.7 7.7 0.0 0.2 12.6 5.3 15.9 23.4 6.5 17.1 0.0 2.6 0.0 11.0 2.4 0.4 0.1 3.1 0.2 7.5 0.9 13.5 0.1 11.0 10.8 1.0 10.7 4.0 5.2 15.9 13.8 21.0 0.3 37.1 26.6 41.1 6.6 8.7 0.1 0.1 0.0 7.5 0.6 8.4 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 27.4 33.1 42.3 24.9 22.6 40.3 79.0 46.2 69.4 64.1 41.8 60.8 16.0 25.6 1.5 170.1 7.4 39.6 47.0 12.0 1.2 2.4 6.2 6.1 278.5 14.3 9.9 18.4 8.4 10.5 1.6 4.4 3.9 9.9 1176.0 13.7 45.3 30.9 6.0 5.7 64.6 8.0 1.8 47.3 1.5 29.3 22.8 0.8 10.8 62.6 11.6 10.1 173.7 1.5 6.1 15.3 28.9 2275.7 14.6 13.0 24.9 72.1 12.8 1.5 1.0 380.5 140.7 19.8 5.5 23.7 0.3 55.1 5.6 22.9 4.0 5.4 13.1 79.7 37.1 17.1 7.6 0.4 24.3 1.9 5.7 0.3 1.7 44.5 SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Bipolar cells: 96.0;Inhibitory neurons: 276.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.6;Hep G2: 65.6;K-562: 44.7;RH-30: 29.0;WM-115: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" 0.6 1.8 2.8 1.3 5.6 0.1 4.1 1.0 2.6 1.4 0.1 6.0 3.0 4.2 0.8 8.9 0.9 2.2 1.2 2.7 4.0 7.4 7.5 3.4 0.3 8.7 4.1 0.4 1.3 5.7 3.8 12.2 9.1 1.4 8.1 8.9 2.3 2.4 0.2 1.9 4.4 3.1 0.0 1.4 4.5 7.6 7.2 0.1 2.1 0.1 0.7 1.5 1.9 0.8 11.2 1.4 1.4 2.0 0.0 0.0 0.1 3.6 1.3 0.3 0.2 16.6 0.1 0.6 3.6 0.0 0.6 0.1 0.3 2.5 0.4 0.0 2.0 0.8 1.5 65.6 0.2 0.0 1.3 0.0 0.1 0.3 0.1 0.0 6.8 0.0 44.7 0.6 4.8 0.1 0.0 0.0 0.1 8.4 2.8 0.0 29.0 6.5 0.1 2.3 0.5 0.1 0.9 0.2 2.8 0.3 0.0 0.0 4.9 0.5 1.5 0.5 1.3 0.1 1.1 0.0 0.1 0.1 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 5.6 1.0 2.6 2.7 4.0 8.7 4.1 9.1 0.0 7.2 0.8 1.7 3.2 5.9 1.3 1.0 1.8 5.6 0.5 2.2 96.0 2.9 23.5 2.6 0.0 0.0 18.4 2.1 0.2 0.0 5.4 9.8 2.2 0.5 1.1 10.7 11.1 16.9 0.0 15.7 0.2 0.3 6.9 19.4 1.8 0.0 7.0 6.1 28.1 0.8 0.0 276.9 11.6 0.0 1.0 1.4 1.3 0.3 0.7 0.0 45.0 0.0 9.2 0.0 5.5 0.9 0.6 3.4 3.4 0.1 3.0 5.2 19.7 0.0 4.0 0.0 3.1 2.0 0.5 0.2 36.4 1.6 0.3 0.5 3.6 25.7 4.2 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SATB1 ENSG00000182568 "SATB homeobox 1" Q01826 3 18345377-18445588 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 374.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 180.2;Inhibitory neurons: 283.4;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 113.7" "Group enriched" "Detected in all" 4 "NK-cells: 63.4;T-cells: 113.7" "Cell line enhanced" "Detected in many" "HDLM-2: 455.3;JURKAT: 213.3;MOLT-4: 107.7;REH: 126.5;THP-1: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051769, CAB056144, HPA070534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies" "CAB056144: AB_10584780, HPA051769: AB_2681600, HPA070534: " "unprognostic (2.16e-1)" "unprognostic (3.99e-1)" "unprognostic (7.13e-2)" "unprognostic (3.58e-1)" "unprognostic (9.15e-2)" "unprognostic (4.22e-3)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (2.90e-2)" "unprognostic (6.14e-2)" "prognostic favorable (8.97e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.96e-7)" "unprognostic (1.92e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-3)" 16.1 10.3 13.4 28.8 19.1 42.8 13.2 0.8 32.2 11.4 2.6 29.9 16.0 13.6 24.0 12.2 17.9 17.6 26.0 23.4 0.4 10.8 15.4 15.7 38.1 0.3 6.1 13.8 28.8 32.4 22.5 4.9 0.0 22.5 18.5 29.8 44.0 25.9 89.5 21.4 21.0 11.8 1.4 27.4 18.5 6.7 0.9 374.2 24.5 49.0 27.8 24.6 12.3 11.0 2.1 0.0 12.7 0.0 17.2 16.6 1.4 3.4 12.3 2.9 9.8 0.5 22.9 4.7 0.4 4.1 1.0 0.2 46.4 5.4 5.9 455.3 28.0 0.1 1.1 0.0 2.5 26.7 3.8 7.4 4.0 0.1 0.6 35.1 3.3 213.3 0.6 24.3 2.2 0.4 107.7 33.9 18.5 1.5 1.5 126.5 6.2 4.9 4.8 15.7 5.9 34.5 0.0 3.9 0.3 10.0 98.5 192.7 1.7 12.6 7.9 5.9 3.7 1.3 0.4 10.0 10.3 101.3 5.7 21.1 1.9 4.6 44.2 2.0 78.6 1.6 29.9 23.0 3.5 13.0 113.7 69.5 4.1 63.4 1.1 4.0 6.0 26.6 13.4 19.1 0.8 32.2 23.4 0.4 0.3 6.1 0.0 1.4 0.9 11.0 19.3 25.6 29.6 48.3 44.6 14.3 12.3 10.9 12.0 12.1 33.2 18.0 70.0 22.8 15.0 31.3 87.6 0.5 71.1 11.0 1.9 16.9 8.2 31.6 15.3 17.0 32.4 22.5 180.2 12.5 0.2 16.4 8.6 11.6 23.4 20.6 35.0 20.9 9.3 0.0 283.4 30.8 4.1 41.5 36.4 4.3 8.4 45.5 10.6 41.2 23.0 15.5 56.7 168.9 28.8 10.5 23.6 8.2 20.6 21.7 24.6 9.1 50.9 63.1 6.6 8.3 10.2 3.2 9.3 20.5 22.0 0.3 84.0 16.8 25.7 19.7 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28259246-28323849 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.8;skeletal muscle: 44.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Excitatory neurons: 38.2;Granulosa cells: 26.3;NK-cells: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 28.8;AN3-CA: 20.9;NTERA-2: 29.6;REH: 32.6;SCLC-21H: 45.5;SH-SY5Y: 42.6" "Region enriched" "Detected in all" 5 "cerebellum: 275.9" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.15e-2)" "prognostic favorable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.1 2.4 8.0 0.9 7.0 1.3 0.8 26.8 15.0 0.7 0.0 0.3 0.3 0.9 0.4 0.6 0.7 0.2 2.1 11.6 6.7 1.8 0.2 0.8 1.7 6.6 7.6 0.5 1.9 2.9 5.6 0.0 6.7 1.5 0.3 5.0 2.7 0.2 44.1 1.1 0.6 0.1 3.2 1.9 0.8 2.5 12.8 10.0 2.5 9.1 0.8 0.3 0.3 7.9 0.3 0.4 28.8 20.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.2 1.4 0.7 0.2 0.0 0.4 0.5 8.8 0.2 0.1 3.0 1.2 0.1 0.3 0.9 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.2 0.2 11.2 0.0 1.8 0.0 3.6 14.0 0.3 29.6 1.9 0.2 32.6 1.6 0.6 0.1 1.8 45.5 42.6 0.8 2.7 0.4 3.5 3.3 0.1 0.8 0.1 4.3 0.4 0.2 0.3 0.0 0.5 0.1 0.5 1.6 0.3 0.0 0.0 1.5 0.0 0.5 0.0 0.4 0.8 0.0 0.1 0.4 1.0 0.0 0.7 0.0 0.0 0.5 0.1 8.0 7.0 26.8 15.0 11.6 6.7 6.6 7.6 6.7 3.2 12.8 7.9 0.2 3.2 0.5 1.0 0.6 0.6 0.7 1.4 3.4 13.0 6.3 2.9 3.6 2.8 2.5 0.0 81.3 0.0 11.1 0.1 1.9 8.2 1.2 2.4 0.3 0.3 6.0 0.4 38.2 5.6 0.0 0.4 0.0 1.8 0.0 26.3 0.0 0.2 0.1 0.0 13.8 0.8 4.1 0.0 0.8 3.9 0.6 0.4 0.0 0.0 0.7 4.1 36.0 5.0 1.7 3.6 0.0 0.0 2.3 1.5 0.1 0.7 1.7 2.7 0.0 2.5 2.7 2.4 2.1 1.0 0.1 0.1 5.6 0.2 1.2 0.4 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1116.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 1240.7;Proximal enterocytes: 769.0;Proximal tubular cells: 881.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 640000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes Nucleoplasm "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favorable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favorable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" 203.7 125.5 68.5 92.7 71.6 111.2 196.6 74.2 90.1 153.8 79.2 256.7 336.3 94.6 165.5 140.2 119.7 144.6 162.4 65.8 76.1 319.8 1116.8 140.6 106.0 75.4 72.3 94.5 119.2 130.9 64.7 79.0 77.9 150.9 270.5 76.6 114.0 97.3 142.0 130.6 305.7 112.9 75.6 83.9 234.4 63.4 74.7 131.9 140.9 152.8 125.5 139.2 76.9 78.9 120.6 64.8 85.5 157.9 273.6 232.6 92.7 140.0 208.9 90.1 129.2 58.7 127.5 114.7 147.6 206.6 105.3 82.5 59.6 131.0 136.5 168.2 86.4 123.4 88.8 122.1 182.0 179.9 197.5 190.2 175.0 107.1 52.9 196.2 260.0 132.6 111.5 58.2 184.7 70.1 200.7 155.2 94.6 304.4 126.0 101.9 150.9 158.3 252.2 192.2 70.9 85.3 122.0 246.3 121.6 189.6 125.9 201.4 203.8 122.4 63.4 213.2 114.9 95.9 131.0 134.2 159.0 175.7 113.8 285.6 193.7 286.0 185.9 208.8 152.1 150.8 144.9 184.6 230.5 132.6 120.8 171.4 29.4 176.8 204.2 150.9 195.2 289.5 68.5 71.6 74.2 90.1 65.8 76.1 75.4 72.3 77.9 75.6 74.7 78.9 167.0 134.6 198.4 52.2 91.1 150.4 123.8 222.2 110.4 37.5 189.8 86.0 157.4 258.7 166.2 185.8 31.3 182.7 128.3 512.7 473.5 168.1 57.4 150.4 81.6 126.8 235.1 93.4 45.0 162.4 156.5 124.3 180.4 125.3 138.4 54.0 146.7 1240.7 203.5 42.1 54.4 462.7 250.3 230.1 173.1 51.4 184.2 148.8 192.1 42.2 154.6 132.0 181.3 48.2 44.3 157.4 503.4 171.9 76.6 118.1 769.0 881.0 178.2 34.1 78.9 72.0 110.6 20.4 19.4 150.0 170.8 133.9 132.9 110.3 336.4 187.8 SCRN2 ENSG00000141295 "Secernin 2" Q96FV2 17 47837692-47841289 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 149.7;Proximal tubular cells: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022934, HPA023434" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA 370000 "Cluster 44: Non-specific - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus" "HPA022934: AB_1856638, HPA023434: AB_1856639" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (2.86e-1)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (1.73e-1)" "prognostic favorable (3.86e-4)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (5.77e-2)" "unprognostic (1.28e-3)" "unprognostic (8.72e-2)" "unprognostic (3.43e-2)" "unprognostic (5.28e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "prognostic favorable (5.83e-4)" 81.2 22.9 18.9 11.1 19.4 13.4 48.9 18.8 22.3 28.2 22.0 23.8 43.8 24.5 11.5 19.2 26.5 12.0 31.9 18.5 20.6 68.6 37.2 17.4 12.9 19.9 19.6 25.4 26.4 25.4 31.5 12.9 18.8 28.5 10.4 6.5 33.8 19.7 38.1 22.1 36.7 10.2 20.1 34.0 21.5 10.6 19.4 12.0 39.9 25.0 10.1 22.2 23.3 20.1 28.0 43.8 12.1 11.0 33.7 25.7 36.6 13.7 27.6 20.6 21.0 32.5 33.2 15.3 27.5 7.1 11.0 14.7 3.9 24.6 6.9 37.6 29.7 15.5 33.8 29.2 12.0 7.9 12.7 25.7 18.1 12.8 9.8 31.5 23.5 35.6 5.4 18.2 28.9 25.4 24.6 12.8 6.0 12.1 17.5 32.7 9.0 62.4 16.9 12.9 8.9 37.6 8.0 17.3 17.8 8.3 37.9 14.5 10.7 18.2 20.8 5.6 6.6 70.2 9.8 7.7 52.1 13.2 4.2 24.5 19.9 43.4 24.6 21.1 24.1 24.8 20.4 24.2 25.7 25.3 31.7 17.8 5.4 29.3 10.8 30.1 23.0 16.5 18.9 19.4 18.8 22.3 18.5 20.6 19.9 19.6 18.8 20.1 19.4 20.1 21.9 38.5 29.9 15.0 18.7 15.7 31.5 41.8 20.5 12.0 24.5 25.7 19.3 15.7 35.9 16.5 10.4 43.1 12.4 33.2 74.3 27.7 3.9 16.9 10.0 24.6 22.3 7.2 12.4 61.0 9.3 25.7 17.3 12.4 16.5 22.1 24.3 26.7 22.7 20.2 10.5 33.6 48.8 11.1 13.7 2.8 33.2 12.8 42.7 7.5 13.9 28.8 26.8 11.1 6.0 33.3 36.5 16.6 30.9 14.1 149.7 332.7 40.9 16.8 6.6 19.1 16.0 5.2 16.7 21.9 11.5 33.8 21.6 23.9 40.7 27.0 SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA034689: AB_2674282, HPA034690: AB_10670574" "unprognostic (5.39e-3)" "unprognostic (4.58e-2)" "unprognostic (2.06e-2)" "unprognostic (3.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (5.85e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (6.62e-3)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" 16.4 16.4 11.8 9.9 14.4 5.2 13.5 14.7 16.0 9.5 7.0 12.9 18.5 11.9 11.4 16.2 10.4 11.2 26.0 10.8 13.6 20.2 22.0 12.2 11.4 14.6 13.4 13.2 14.7 27.7 14.0 13.1 13.6 15.2 13.2 22.8 11.0 12.5 40.5 13.8 14.3 14.0 12.9 11.8 12.4 10.6 14.1 12.4 20.3 35.8 12.1 10.4 8.3 18.5 15.9 9.7 25.8 22.8 18.8 21.1 13.7 24.1 19.0 18.2 22.0 9.6 11.4 3.0 15.6 24.2 14.0 15.5 19.3 21.1 23.9 34.8 17.8 29.7 21.1 7.5 27.8 22.8 15.0 23.5 25.4 34.4 24.5 20.4 21.8 16.7 20.2 11.1 25.0 18.0 18.9 22.2 12.0 35.4 41.0 9.3 25.7 17.5 21.2 16.5 16.0 44.5 16.6 16.2 30.7 26.4 21.8 21.7 15.7 20.9 10.9 25.6 21.0 29.4 32.8 0.5 22.9 11.2 21.8 7.2 5.2 2.2 4.8 3.3 3.4 8.6 5.1 4.6 5.1 11.0 7.8 6.3 20.0 6.9 4.3 8.0 5.6 2.6 11.8 14.4 14.7 16.0 10.8 13.6 14.6 13.4 13.6 12.9 14.1 18.5 7.8 9.6 15.6 18.6 7.0 3.6 12.1 23.7 12.5 12.8 7.9 6.3 22.8 4.3 12.5 9.2 10.4 10.7 3.8 8.4 13.7 9.1 5.1 9.4 8.3 6.0 6.0 11.6 21.0 9.8 6.3 6.9 11.2 5.4 8.8 9.5 8.6 8.7 9.3 18.5 26.3 7.3 20.3 5.8 2.2 4.0 4.7 6.2 3.6 6.5 6.1 22.6 7.2 27.6 25.7 12.2 4.0 6.8 10.3 5.4 9.9 12.5 13.6 15.0 0.0 8.2 7.1 18.9 7.1 20.4 4.8 6.8 5.8 13.0 6.4 9.7 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" 86.5 91.8 44.2 78.8 47.8 56.2 80.2 47.2 65.3 84.4 72.5 95.9 117.1 91.8 43.9 66.3 74.6 66.2 134.6 45.5 44.8 89.6 160.7 82.0 53.4 53.2 46.1 85.4 104.6 61.5 78.5 73.3 47.0 76.9 60.4 25.7 83.5 52.2 78.9 72.9 116.8 58.2 43.5 78.0 93.6 71.7 50.5 34.6 81.8 47.7 39.6 82.2 71.6 45.9 139.7 123.7 67.1 214.0 320.0 160.4 80.5 266.1 241.4 191.2 159.4 147.0 236.2 87.8 201.8 258.0 137.4 140.4 77.5 117.1 58.2 147.9 133.0 153.6 185.7 207.8 147.4 156.7 199.2 199.0 59.5 144.6 81.2 186.5 155.9 57.3 129.2 225.0 95.7 101.1 77.8 158.9 61.7 158.0 167.1 85.8 86.5 234.4 127.2 66.4 243.3 86.7 177.2 208.2 182.8 59.0 108.0 176.7 198.8 196.2 107.0 149.5 154.2 138.9 141.2 144.6 222.9 289.7 87.1 14.4 21.5 30.8 19.3 14.6 14.6 13.5 27.6 28.4 21.9 16.8 16.0 14.1 16.9 26.8 23.2 14.0 25.1 11.8 44.2 47.8 47.2 65.3 45.5 44.8 53.2 46.1 47.0 43.5 50.5 45.9 92.9 22.4 19.2 18.6 62.5 119.8 74.0 24.6 46.7 34.5 51.2 47.6 35.7 68.6 28.9 49.7 18.8 124.1 68.4 240.0 11.7 79.0 39.1 49.0 76.2 77.8 65.5 32.8 21.1 71.4 284.4 117.1 81.1 60.8 36.2 61.4 76.4 117.1 122.4 38.7 23.5 174.9 30.5 73.7 154.8 36.8 95.4 62.8 167.2 13.1 50.8 64.9 111.2 13.6 17.5 73.0 213.5 76.0 202.5 101.5 406.2 57.7 18.4 40.0 59.2 69.8 75.1 101.7 63.5 53.2 114.2 168.0 73.4 88.7 181.0 71.1 SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 159.7;Kupffer cells: 84.9;Macrophages: 64.8;monocytes: 123.8;NK-cells: 154.5;Plasma cells: 65.1;T-cells: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 136.2;HMC-1: 130.0;JURKAT: 102.2;Karpas-707: 195.1;RPMI-8226: 286.7;U-266/70: 326.8;U-266/84: 214.5" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" 17.5 9.1 12.1 47.4 10.5 21.1 6.9 11.7 12.1 9.2 8.2 9.6 8.6 3.7 2.1 8.6 7.8 17.0 5.0 12.0 14.1 4.0 6.5 40.8 62.2 17.8 13.5 2.8 3.4 4.4 3.0 13.0 16.4 3.3 8.4 0.7 7.0 3.9 2.2 4.7 15.5 11.5 17.0 86.6 11.3 2.2 17.2 52.1 3.4 7.3 30.6 21.5 3.3 24.5 0.5 0.4 1.4 0.8 0.7 1.5 0.8 4.9 4.8 1.8 1.4 0.3 1.9 0.5 1.7 7.4 2.0 0.3 0.1 0.1 1.3 136.2 0.0 45.7 0.2 0.2 0.4 35.1 130.0 1.8 0.5 2.5 0.6 5.0 0.4 102.2 0.8 195.1 6.0 0.0 28.3 18.9 0.2 0.1 1.6 0.3 0.5 286.7 2.9 0.0 0.3 0.0 0.6 0.2 2.2 3.3 0.1 42.6 1.7 2.6 0.8 3.5 1.4 326.8 214.5 6.4 1.5 74.2 1.9 1543.6 297.6 940.2 419.2 509.2 344.3 22.0 396.6 362.9 299.9 22.3 300.3 323.7 1257.2 309.2 762.7 518.3 662.2 1035.5 12.1 10.5 11.7 12.1 12.0 14.1 17.8 13.5 16.4 17.0 17.2 24.5 1.2 3.2 12.4 0.0 11.6 3.4 0.1 0.2 0.0 0.2 0.6 1.4 2.2 4.3 2.7 0.0 0.0 0.5 159.7 0.2 0.0 0.3 8.2 1.8 0.6 2.6 0.0 10.9 0.2 0.2 2.3 2.4 2.6 0.9 29.7 0.4 3.6 2.2 40.1 0.0 0.3 0.0 0.0 84.9 49.6 12.2 0.3 64.8 7.2 15.9 123.8 0.0 154.5 0.0 0.1 0.5 0.0 0.0 65.1 0.1 0.0 0.5 6.4 0.2 0.0 1.2 0.9 0.8 0.5 0.5 1.8 1.0 65.9 0.1 0.0 0.0 SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 1189.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.2;fHDF/TERT166: 37.1;RT4: 66.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 13000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" "HPA004632: AB_1079905" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "unprognostic (6.67e-2)" "unprognostic (3.65e-1)" "prognostic favorable (2.45e-4)" "unprognostic (7.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (8.15e-2)" "prognostic favorable (3.66e-8)" "unprognostic (8.51e-3)" "unprognostic (1.27e-2)" "unprognostic (3.57e-1)" "unprognostic (3.01e-2)" 4.6 1.2 7.8 2.7 9.1 0.0 6.8 5.6 23.6 13.0 3.6 9.5 2.9 8.9 2.2 3.1 2.9 5.4 9.5 35.4 17.0 11.6 4.9 11.1 4.7 10.9 11.1 1.7 4.4 1.9 2.3 7.0 17.1 2.9 7.5 7.0 2.1 4.9 1.3 4.4 5.3 2.4 8.3 6.3 1.9 1.6 16.4 1.7 1.9 3.1 3.7 5.8 3.8 13.4 0.0 0.0 15.0 0.0 10.1 14.1 0.0 24.2 64.2 4.7 2.5 0.0 0.1 0.0 0.0 37.1 0.3 21.6 0.0 1.4 2.4 0.0 0.2 0.0 0.1 0.0 1.4 0.0 0.1 3.6 0.7 5.3 21.6 10.5 0.0 0.0 0.0 0.0 5.7 0.7 0.0 0.0 1.5 13.2 1.1 0.0 0.0 0.9 1.8 66.7 3.1 0.3 0.2 0.0 19.9 5.1 0.0 0.0 0.0 23.0 0.5 0.0 0.5 0.0 0.0 0.0 21.4 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 7.8 9.1 5.6 23.6 35.4 17.0 10.9 11.1 17.1 8.3 16.4 13.4 8.0 150.6 5.6 63.6 0.3 9.2 6.4 30.8 8.0 2.8 1.6 49.0 37.0 22.8 14.3 1.8 0.0 1.8 9.6 23.9 0.0 3.4 32.6 6.3 151.5 6.4 5.4 0.0 60.6 2.3 1.2 27.8 0.5 9.3 1.3 1.8 5.3 4.3 1.3 247.3 53.1 10.9 0.0 0.0 5.2 50.5 10.2 0.8 33.8 134.9 0.1 44.8 0.0 1189.7 152.3 1.2 8.0 14.7 0.0 8.2 16.9 14.4 2.0 3.6 39.5 4.3 40.5 0.6 0.5 11.4 4.8 1.9 1.4 29.0 20.5 14.1 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 231.3" "Cell type enhanced" "Detected in some" "B-cells: 20.3;Cytotrophoblasts: 43.9;dendritic cells: 66.5;Extravillous trophoblasts: 50.1;Hofbauer cells: 54.8;Plasma cells: 28.4;Syncytiotrophoblasts: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 273.0;MOLT-4: 300.5;REH: 271.8;SH-SY5Y: 394.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Supported Approved Cytosol NA NA 2900000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (6.35e-3)" "unprognostic (1.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-1)" "unprognostic (1.73e-1)" "unprognostic (6.23e-2)" "unprognostic (2.13e-1)" "unprognostic (7.24e-2)" "unprognostic (6.27e-2)" "unprognostic (1.46e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-1)" "unprognostic (2.88e-1)" "unprognostic (1.92e-1)" "unprognostic (2.60e-2)" 13.1 73.4 14.5 66.7 12.8 61.1 12.7 16.9 16.9 11.5 7.8 47.4 14.3 11.2 16.9 17.9 18.1 17.5 16.1 12.4 20.8 18.1 21.3 16.5 119.7 18.3 18.0 11.4 4.6 9.9 9.8 14.7 22.1 13.4 18.5 38.9 18.2 40.5 4.6 7.1 35.3 24.4 13.5 61.9 20.0 40.3 20.5 231.3 7.6 5.9 103.9 18.6 9.7 12.0 6.5 10.1 37.9 68.5 3.5 7.7 53.9 18.9 41.7 31.4 53.8 3.4 14.4 130.7 14.6 23.9 32.6 3.7 60.2 12.1 21.7 80.6 13.9 58.1 20.3 23.5 9.1 66.3 29.4 14.0 2.6 24.8 0.6 13.1 46.4 273.0 43.6 68.0 18.7 4.8 300.5 38.6 40.2 1.9 31.0 271.8 31.3 106.7 33.5 6.8 16.8 394.7 49.1 17.9 20.6 40.7 24.3 33.8 29.0 8.5 17.2 27.5 4.7 33.8 14.5 170.7 0.8 69.0 6.3 34.2 17.2 39.9 58.6 26.1 61.4 65.0 75.3 68.6 34.0 64.0 79.3 69.4 11.8 81.3 38.8 63.7 112.4 53.9 14.5 12.8 16.9 16.9 12.4 20.8 18.3 18.0 22.1 13.5 20.5 12.0 13.8 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 43.9 66.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 43.0 15.5 0.0 0.0 0.0 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 118.8;skeletal muscle: 158.0;tongue: 144.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 134.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 66.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007476 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" 14.3 0.6 0.0 0.1 0.1 0.0 2.2 0.0 1.9 0.4 0.0 1.1 0.1 0.1 8.0 3.3 1.1 0.8 118.8 0.1 0.0 0.3 0.0 4.8 0.0 0.3 0.0 0.2 0.1 2.1 0.3 0.0 0.2 3.2 0.6 0.3 4.3 0.4 158.0 3.4 0.6 0.1 0.0 0.1 0.9 1.5 0.2 0.1 0.1 144.1 0.1 3.0 1.4 0.4 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 66.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 0.2 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.0 0.3 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 1.3 0.0 0.0 12.5 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 3.4 3.0 7.5 0.2 5.4 1.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 1.2 3.8 13.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 161.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.3;Excitatory neurons: 86.5;Intestinal goblet cells: 87.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "CACO-2: 81.6;HEL: 41.8;OE19: 99.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" 26.4 6.9 18.8 7.5 18.6 1.7 21.6 15.6 27.5 22.3 15.1 50.5 35.2 9.9 24.7 55.1 17.8 23.2 6.8 21.4 21.8 15.7 53.1 12.7 5.5 26.7 22.0 4.1 23.3 31.5 16.6 24.0 28.1 26.2 47.9 26.0 161.7 11.4 4.8 11.3 35.6 15.8 24.1 6.6 68.9 2.1 24.2 4.8 59.1 10.1 10.7 12.7 19.7 22.5 8.5 1.5 7.6 1.6 6.7 5.6 18.0 0.5 5.6 1.9 4.0 81.6 16.3 0.1 11.4 0.5 1.6 3.9 7.0 9.2 6.7 0.0 10.2 41.8 1.8 15.8 2.8 1.7 1.1 3.1 7.3 5.8 3.3 2.7 23.8 0.0 16.8 0.0 0.7 1.3 0.0 0.2 6.5 99.7 2.8 0.0 2.2 0.2 2.0 27.3 20.3 22.3 0.5 2.4 0.6 10.3 0.4 3.5 13.6 5.2 3.4 0.1 4.9 12.0 6.0 0.0 0.9 0.0 1.6 11.1 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.0 2.2 0.0 0.0 0.1 0.0 8.8 18.8 18.6 15.6 27.5 21.4 21.8 26.7 22.0 28.1 24.1 24.2 22.5 83.2 6.4 24.8 20.9 0.9 2.2 4.6 3.3 2.2 13.5 14.8 9.9 6.1 52.9 21.4 22.0 8.4 40.4 1.7 156.3 0.0 14.8 18.1 14.3 3.7 33.8 12.6 7.4 86.5 13.0 3.7 4.6 81.1 21.0 0.0 2.0 44.6 69.6 4.1 13.5 38.1 87.8 4.1 2.9 2.1 20.3 0.6 21.6 16.0 11.2 4.6 8.6 0.0 33.7 24.9 15.0 76.0 4.5 1.3 19.7 48.7 11.3 24.6 12.2 0.0 3.7 4.7 2.5 1.2 21.5 0.9 52.7 1.0 1.8 67.2 29.9 SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.8;monocytes: 289.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" 45.1 11.0 17.1 45.5 16.8 68.6 26.6 14.2 20.3 18.2 47.3 37.1 13.7 10.6 11.3 8.5 11.9 21.2 24.4 16.4 20.8 13.5 15.6 26.0 68.1 19.9 22.9 8.7 6.9 14.4 11.9 32.5 20.3 6.7 35.3 5.1 10.4 7.4 13.0 24.0 18.4 14.8 18.5 37.0 18.9 5.7 26.0 55.0 20.5 32.4 68.7 17.7 11.2 27.1 52.5 54.3 8.4 19.4 41.6 80.0 44.2 46.4 67.4 23.3 37.2 37.2 105.6 97.4 47.6 67.5 67.0 5.9 19.8 18.4 37.3 32.3 13.4 21.2 13.6 30.1 27.2 134.0 160.2 47.4 18.0 48.5 141.9 64.6 35.4 67.6 8.0 114.2 59.7 23.5 80.4 135.4 14.8 63.1 71.2 49.1 82.0 9.1 27.1 10.6 6.0 6.2 43.2 5.6 65.3 53.8 5.4 155.2 113.6 40.6 34.9 52.2 51.9 165.6 119.0 86.0 86.5 109.4 183.5 49.2 104.7 171.1 180.2 77.7 140.4 55.4 174.2 187.8 132.6 50.3 143.3 142.5 210.0 76.5 96.9 148.4 224.1 195.9 17.1 16.8 14.2 20.3 16.4 20.8 19.9 22.9 20.3 18.5 26.0 27.1 40.3 16.0 54.4 5.5 75.6 12.0 3.5 7.5 5.2 5.1 5.4 6.2 78.1 11.5 25.0 9.2 16.7 26.2 174.3 207.8 1.9 8.3 0.7 6.3 28.5 26.5 50.8 23.3 72.3 18.9 39.3 56.9 23.4 8.3 96.6 5.9 27.8 17.6 55.8 8.4 126.3 34.4 10.2 87.4 102.1 1.9 52.8 113.0 33.8 108.7 289.2 0.1 175.1 87.0 145.9 48.0 153.3 38.4 63.5 3.5 26.4 40.3 20.1 2.8 59.2 12.1 72.2 24.3 22.7 1.9 10.9 22.6 138.7 26.7 59.4 7.7 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Cone photoreceptor cells: 47.9;Microglial cells: 24.4;Peritubular cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 19.2;SK-MEL-30: 18.2;SuSa: 18.6;WM-115: 23.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051646 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: AB_2681562" "unprognostic (8.65e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (6.99e-3)" "unprognostic (8.05e-2)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (9.73e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (1.93e-1)" "unprognostic (7.67e-3)" 0.7 1.8 4.3 0.4 6.0 0.0 1.0 3.6 10.1 2.4 5.4 1.5 0.7 1.5 2.7 5.0 1.6 3.1 0.7 5.9 4.0 3.7 4.0 4.1 0.3 4.8 5.0 6.9 3.7 2.4 4.4 7.6 4.3 5.3 1.3 20.8 3.2 2.6 0.1 4.1 0.5 0.8 4.3 0.7 1.5 3.4 4.7 3.6 1.4 0.1 1.3 2.4 3.1 5.2 6.2 0.7 11.0 1.5 0.6 1.7 6.2 0.6 2.0 2.4 3.8 7.5 0.1 0.0 2.0 1.6 0.4 4.8 5.7 15.9 2.8 0.0 4.3 0.0 0.0 1.2 3.5 0.0 7.4 0.3 10.9 18.0 0.7 3.9 13.7 0.0 0.0 0.0 3.9 6.5 0.0 0.1 9.7 0.0 0.0 0.0 12.1 0.0 10.2 19.2 1.6 0.9 0.5 0.1 18.2 18.6 6.5 0.4 6.4 17.3 2.2 0.1 0.6 0.0 0.0 0.0 11.4 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 6.0 3.6 10.1 5.9 4.0 4.8 5.0 4.3 4.3 4.7 5.2 1.1 0.0 1.5 26.4 0.0 1.9 3.3 2.8 10.8 9.5 3.4 1.7 4.1 4.3 3.1 3.7 47.9 8.9 0.0 2.0 3.9 3.0 0.5 4.8 2.5 7.2 1.2 2.7 9.5 0.0 1.3 1.5 3.1 5.9 0.0 5.4 10.0 5.7 0.7 1.7 9.5 0.3 4.1 0.8 0.0 1.0 3.7 0.2 0.0 24.4 0.0 2.4 0.0 9.5 4.6 1.6 0.1 83.1 0.0 5.4 0.1 1.0 2.8 18.0 0.0 0.6 1.8 0.1 1.1 10.8 2.0 2.1 0.5 5.5 0.9 5.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SINHCAF "C12orf14, FAM60A, TERA" ENSG00000139146 "SIN3-HDAC complex associated factor" Q9NP50 12 31280584-31327058 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.5;Extravillous trophoblasts: 118.8;Glandular and luminal cells: 149.3;monocytes: 154.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NTERA-2: 600.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038167, HPA057585" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA038167: AB_10675629, HPA057585: AB_2732615" "unprognostic (2.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.85e-2)" "unprognostic (8.91e-2)" "unprognostic (2.80e-3)" "unprognostic (1.84e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (1.15e-1)" "prognostic favorable (7.89e-4)" "unprognostic (3.22e-1)" "unprognostic (2.49e-1)" "unprognostic (3.07e-1)" "unprognostic (9.75e-2)" 16.2 11.6 1.1 22.8 2.0 25.6 26.7 2.8 2.0 24.0 10.1 24.3 21.5 51.9 18.0 25.1 36.2 15.2 8.7 1.0 1.1 36.3 7.7 16.6 34.4 2.0 1.5 28.1 22.6 22.6 24.8 26.3 1.5 26.9 25.9 4.0 25.8 30.3 3.2 24.0 19.6 33.3 1.5 17.4 19.5 17.0 1.3 50.9 14.0 3.6 33.6 34.1 23.7 1.4 27.8 29.9 128.7 26.6 8.0 12.0 238.3 10.7 10.3 25.9 36.7 91.6 74.8 95.9 94.9 3.9 26.7 48.1 105.4 48.4 51.0 92.6 42.6 61.7 21.2 66.6 28.4 105.2 54.7 13.0 82.0 21.6 102.2 45.3 61.6 98.9 88.0 39.1 11.4 17.5 173.7 71.7 600.6 81.7 19.0 159.6 62.4 80.0 57.3 67.8 180.0 113.5 26.5 54.1 71.8 280.2 24.6 64.5 58.5 6.0 36.1 2.8 46.4 40.3 50.5 156.9 17.9 42.9 34.0 29.5 12.9 19.8 21.8 15.8 24.8 59.1 30.4 25.9 27.5 48.5 35.8 29.0 3.9 50.4 24.2 71.9 15.3 29.6 1.1 2.0 2.8 2.0 1.0 1.1 2.0 1.5 1.5 1.5 1.3 1.4 31.0 76.9 35.8 0.0 26.5 0.0 0.0 0.0 0.0 0.0 52.3 48.8 0.0 0.0 56.3 46.0 0.0 75.1 37.7 0.0 82.2 70.1 0.0 150.5 37.8 21.8 0.0 0.0 0.0 43.2 118.8 14.9 0.0 149.3 11.4 48.8 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 154.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 11.1 0.0 0.0 41.1 59.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 60.5 18.6 18.3 0.0 0.0 SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.2;Inhibitory neurons: 95.9;Microglial cells: 183.6;Oligodendrocyte precursor cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 69.7;NTERA-2: 53.9;WM-115: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" 12.1 3.3 8.5 6.4 7.2 5.4 9.2 9.6 11.7 10.0 0.5 19.4 3.9 4.4 2.8 20.3 4.5 8.5 31.3 9.6 16.0 7.7 6.4 16.2 3.0 44.0 21.7 11.9 3.6 4.4 8.1 18.3 44.6 8.1 18.9 14.7 8.7 4.7 7.1 9.0 9.2 7.4 14.4 9.6 5.7 7.2 18.7 2.4 8.0 9.5 3.3 12.5 14.9 9.0 0.0 7.5 69.7 0.2 0.6 0.0 29.3 1.2 2.5 3.1 2.2 2.9 0.1 5.9 13.3 26.4 2.9 1.7 13.8 2.3 2.9 0.0 12.8 0.0 7.0 0.0 5.9 1.0 7.2 3.8 9.1 0.6 6.2 0.0 15.7 25.4 0.0 0.1 1.6 3.5 7.4 0.7 53.9 0.2 10.2 0.0 0.0 3.4 8.1 11.5 3.5 11.9 23.8 0.8 9.5 15.8 1.4 0.6 5.6 8.1 0.0 17.8 2.9 6.5 0.0 0.0 10.0 6.2 46.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.3 0.3 0.0 0.1 8.5 7.2 9.6 11.7 9.6 16.0 44.0 21.7 44.6 14.4 18.7 9.0 53.7 6.4 1.8 22.9 0.8 8.8 9.8 8.7 15.4 23.5 10.7 8.6 62.6 12.8 10.4 3.7 52.1 4.9 4.4 29.9 0.0 7.1 11.7 19.0 21.4 22.7 7.2 0.4 80.2 0.5 7.1 15.2 5.1 47.5 1.3 16.0 1.8 3.8 10.0 5.0 95.9 29.5 14.2 16.6 7.2 9.8 0.9 19.5 14.2 183.6 6.3 12.7 1.0 104.0 21.0 1.4 39.9 1.9 0.5 13.2 9.1 0.4 7.7 35.7 0.0 21.8 23.9 6.9 24.0 45.8 7.4 14.8 2.0 11.9 23.4 23.0 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 36.9;Kupffer cells: 19.8;Langerhans cells: 61.8;Macrophages: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.7;HL-60: 1.4;U-138 MG: 1.9;U-87 MG: 1.0;U-937: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" 6.9 3.7 1.7 29.8 1.8 0.9 3.0 1.8 3.6 3.8 2.9 7.6 6.6 1.5 0.7 4.2 2.8 8.0 2.6 1.4 2.3 3.9 3.3 16.1 32.9 4.9 3.9 2.8 2.1 0.6 3.5 5.5 5.3 2.5 9.5 0.3 3.4 1.4 0.9 2.8 9.3 7.6 2.5 11.7 4.9 0.8 9.2 10.5 3.0 0.6 17.7 10.3 2.1 4.9 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 1.0 1.2 0.0 0.0 5.8 0.0 3.5 8.0 0.2 0.0 1.2 4.6 14.3 0.0 0.2 2.7 0.5 8.8 0.5 0.1 0.0 3.1 1.7 1.8 1.8 3.6 1.4 2.3 4.9 3.9 5.3 2.5 9.2 4.9 0.3 0.0 2.3 0.0 1.0 1.8 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.1 0.8 0.0 0.4 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.2 36.9 0.0 0.1 0.0 0.0 19.8 61.8 0.0 0.3 41.1 0.0 1.0 1.3 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 2.9 0.1 0.0 0.0 1.0 0.5 1.3 0.0 0.0 0.0 SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "brain: 405.4;retina: 315.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 362.7;Cone photoreceptor cells: 369.1;Excitatory neurons: 107.8;Rod photoreceptor cells: 358.0" "Cancer enriched" "Detected in some" 6 "glioma: 7.5" "Group enriched" "Detected in many" 7 "amygdala: 176.7;basal ganglia: 243.4;cerebral cortex: 289.7;hippocampal formation: 405.4;white matter: 169.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 20.8;K-562: 7.0;REH: 4.0;SCLC-21H: 4.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 201.2;cerebellum: 204.6;cerebral cortex: 339.5;hippocampal formation: 471.2" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB037183: AB_261840, HPA050458: AB_2681134, HPA063679: AB_2685086" "unprognostic (1.79e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (9.12e-2)" "unprognostic (3.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.32e-2)" "unprognostic (6.61e-2)" "unprognostic (4.26e-12)" "unprognostic (8.36e-4)" "unprognostic (4.27e-1)" "unprognostic (1.35e-2)" "unprognostic (6.17e-3)" 5.7 1.4 176.7 0.2 243.4 0.0 3.0 32.2 289.7 2.0 0.0 1.5 0.4 1.2 0.6 1.1 2.2 0.9 2.8 405.4 0.0 1.0 0.3 0.6 1.0 31.7 0.8 0.6 0.6 0.6 1.6 0.1 37.8 0.5 0.5 315.8 1.2 0.3 1.7 2.2 1.5 0.6 0.0 0.1 0.9 2.3 0.0 0.3 2.3 2.5 0.6 1.6 1.8 169.9 0.0 0.3 0.2 0.4 1.6 0.3 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.3 0.5 1.2 0.1 1.9 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.1 0.3 0.0 0.3 0.0 0.3 7.0 1.0 0.0 0.2 0.0 0.1 0.0 0.3 0.3 4.0 0.1 0.1 0.0 0.0 4.9 0.4 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.3 2.3 0.9 0.0 0.4 0.3 0.3 0.6 2.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.7 243.4 32.2 289.7 405.4 0.0 31.7 0.8 37.8 0.0 0.0 169.9 1.9 0.0 0.0 9.4 0.0 1.3 0.2 0.0 0.0 362.7 0.5 0.8 3.2 0.0 0.0 0.0 369.1 0.1 0.0 0.2 0.0 0.0 5.6 0.0 0.0 1.7 0.0 0.0 107.8 0.0 0.1 5.5 0.0 0.1 0.0 0.1 0.0 0.0 0.3 11.8 3.4 0.0 0.0 0.0 1.3 0.5 6.5 0.3 1.8 11.2 0.0 22.6 0.0 6.0 8.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 358.0 6.6 0.4 4.3 3.5 4.4 0.6 0.6 0.0 0.1 0.0 0.3 0.1 SLC1A1 "EAAC1, EAAT3" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 45.0;intestine: 64.7;kidney: 51.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.5;Glandular and luminal cells: 98.7;Hepatocytes: 68.4;Microglial cells: 67.5;Oligodendrocyte precursor cells: 161.4;Proximal enterocytes: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.1;HDLM-2: 70.9;HUVEC TERT2: 32.5;RPTEC TERT1: 66.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" 4.6 1.7 13.2 2.3 15.4 0.1 4.1 9.5 14.8 5.8 12.9 12.4 34.8 3.7 45.0 2.3 2.6 25.5 2.8 16.5 12.6 51.0 41.2 20.9 2.6 10.8 13.0 0.6 2.1 0.3 6.8 8.1 13.6 6.3 10.2 6.0 4.8 3.2 1.4 1.5 64.7 3.2 10.9 0.4 5.2 0.8 13.9 0.4 29.5 1.3 8.2 5.6 1.5 10.1 0.1 2.0 1.6 9.5 24.3 29.1 8.3 10.4 21.4 3.2 3.1 17.2 0.5 13.7 0.6 5.4 3.9 0.0 3.6 5.7 2.9 70.9 4.5 0.0 13.6 0.1 0.8 0.9 0.0 2.0 0.2 12.1 0.0 1.6 32.5 0.2 0.0 0.0 2.2 0.3 0.0 0.3 4.2 10.5 1.8 0.0 0.0 0.2 66.4 6.1 2.2 2.0 0.8 3.8 0.0 7.7 1.4 0.5 17.6 4.9 0.4 9.5 3.0 0.1 0.1 0.0 23.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.2 15.4 9.5 14.8 16.5 12.6 10.8 13.0 13.6 10.9 13.9 10.1 12.2 163.5 3.2 4.2 0.4 0.0 1.1 0.6 4.6 3.9 2.0 0.8 2.3 28.6 6.1 0.0 0.0 0.1 0.0 52.4 3.9 8.1 4.3 10.7 13.3 10.6 0.0 0.0 48.4 0.8 0.0 1.8 2.0 98.7 0.0 0.6 2.5 68.4 0.1 0.0 50.3 10.1 0.0 1.3 0.3 11.2 0.3 1.1 0.0 67.5 0.0 0.8 0.0 161.4 3.5 9.3 10.6 0.0 0.0 2.4 110.6 43.1 3.3 1.1 0.0 0.5 3.1 0.1 0.2 1.0 0.6 0.1 1.4 0.4 8.5 1.8 SLC22A17 "BOCT, BOIT, NGALR" ENSG00000092096 "Solute carrier family 22 member 17" Q8WUG5 14 23346306-23352912 "Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 304.0;choroid plexus: 372.6;pituitary gland: 149.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 71.4;Horizontal cells: 201.9;Inhibitory neurons: 111.1;Muller glia cells: 74.2;Oligodendrocyte precursor cells: 120.6" "Cancer enhanced" "Detected in all" "glioma: 51.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.7;AN3-CA: 31.4;ASC diff: 23.2;SH-SY5Y: 41.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002728 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA002728: AB_1079998" "unprognostic (9.34e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.23e-3)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.31e-2)" "unprognostic (1.26e-2)" "unprognostic (4.23e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.73e-4)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (3.50e-2)" "unprognostic (1.23e-2)" "unprognostic (3.87e-2)" 7.3 30.1 159.4 3.9 159.6 0.6 11.8 98.0 159.1 25.4 372.6 24.6 4.6 14.8 10.3 4.4 19.1 6.4 22.0 145.5 304.0 16.3 2.5 8.3 3.4 165.6 143.8 17.0 17.2 11.4 149.1 5.0 145.5 39.8 2.4 26.4 25.4 25.7 1.5 7.6 10.2 7.0 125.5 4.2 13.3 8.9 231.8 1.7 19.1 2.7 1.6 15.2 17.9 139.5 0.0 1.9 20.7 31.4 23.2 11.4 3.4 7.5 11.6 2.5 1.9 0.0 1.9 0.0 2.8 11.0 6.6 0.4 0.7 0.5 0.0 0.0 1.4 4.4 0.0 0.2 13.1 0.0 4.4 16.7 1.2 2.6 0.0 11.3 0.8 9.1 0.0 0.2 3.8 3.2 0.1 0.2 11.3 0.0 0.0 0.0 0.7 0.2 0.0 2.0 19.9 41.5 5.8 0.0 0.0 4.0 3.5 0.6 0.0 2.9 8.9 16.6 0.0 0.1 3.2 0.0 1.9 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 159.4 159.6 98.0 159.1 145.5 304.0 165.6 143.8 145.5 125.5 231.8 139.5 7.7 0.0 2.7 46.7 2.3 12.6 18.6 2.6 12.5 53.0 23.4 30.1 10.0 2.8 5.5 20.2 43.8 2.4 1.0 0.0 1.9 0.7 0.2 1.8 10.6 12.0 20.8 1.7 71.4 1.3 4.9 21.7 3.6 0.6 4.5 12.0 16.8 0.9 1.0 201.9 111.1 0.0 0.0 0.6 5.1 2.3 21.1 1.2 7.2 19.7 0.7 74.2 0.0 120.6 49.2 1.5 0.0 42.9 9.2 31.3 0.0 16.9 3.2 69.0 0.0 14.1 18.0 1.1 2.3 3.0 10.9 4.8 2.0 4.5 0.3 6.1 SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.7;Excitatory neurons: 148.5;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" 11.1 11.5 8.5 4.0 9.0 2.8 11.6 9.3 12.3 11.5 6.1 25.2 2.2 13.4 4.3 12.7 11.7 3.7 62.7 8.9 9.0 13.4 1.8 7.1 4.4 6.9 6.7 14.5 3.9 12.0 17.1 3.2 6.8 13.7 6.1 15.8 16.8 9.5 97.0 14.5 10.7 8.5 5.8 8.9 16.4 6.1 7.4 5.6 15.1 51.1 5.2 16.2 12.4 8.4 4.9 3.0 4.2 8.0 9.5 11.7 0.0 5.3 11.2 7.7 7.3 2.2 3.2 14.5 2.6 7.5 4.3 4.3 7.9 8.5 10.7 6.3 10.4 6.9 4.4 5.5 3.8 14.8 4.9 12.6 7.0 11.0 2.3 4.1 8.0 7.0 5.0 5.2 4.4 3.2 9.7 6.5 3.0 3.8 4.7 9.6 4.7 7.4 8.0 4.5 5.1 1.6 2.6 8.5 4.0 2.5 2.8 3.1 6.4 6.2 2.0 6.0 3.2 8.8 4.2 13.6 9.1 7.5 2.9 0.0 0.4 0.1 1.0 0.4 0.8 0.7 0.5 0.9 0.4 0.5 0.9 1.5 0.0 0.9 0.7 0.1 0.7 0.4 8.5 9.0 9.3 12.3 8.9 9.0 6.9 6.7 6.8 5.8 7.4 8.4 9.8 0.0 9.8 71.2 11.3 6.9 10.2 13.2 19.9 25.5 9.3 11.8 97.7 0.0 18.4 18.4 25.0 7.5 10.7 11.6 19.6 1.7 3.2 5.0 10.3 8.7 14.4 6.9 148.5 3.3 1.8 15.1 12.8 6.1 10.8 7.3 7.9 0.6 4.5 37.0 175.2 6.1 16.2 8.4 5.4 2.1 12.5 7.2 16.0 25.3 9.7 19.8 5.2 111.6 44.1 2.0 4.7 24.5 19.5 4.6 4.1 13.2 11.2 25.5 13.1 12.5 16.6 7.8 9.1 16.8 7.7 1.2 15.0 11.0 7.6 8.3 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 67.6;skeletal muscle: 80.2;tongue: 29.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 53.0" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.8 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.2 0.1 0.0 67.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 80.2 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 29.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.4 0.2 0.2 1.1 0.4 0.1 0.4 0.1 0.1 0.2 0.1 0.8 0.6 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.9 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 SLC39A8 BIGM103 ENSG00000138821 "Solute carrier family 39 member 8" Q9C0K1 4 102251041-102431258 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 171.1" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 778.8;Alveolar cells type 2: 305.6;Extravillous trophoblasts: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 158.9;HL-60: 120.9;Karpas-707: 171.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038832, HPA038833" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA038832: AB_2676226, HPA038833: AB_10670910" "prognostic favorable (6.69e-4)" "unprognostic (1.29e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (6.50e-2)" "unprognostic (9.59e-2)" "unprognostic (6.07e-2)" "unprognostic (2.74e-1)" "unprognostic (1.20e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-3)" "unprognostic (2.78e-2)" "prognostic favorable (6.34e-6)" "unprognostic (3.25e-1)" "unprognostic (6.54e-2)" "unprognostic (6.40e-2)" "unprognostic (7.13e-3)" 45.5 3.5 9.6 28.9 10.7 36.5 18.1 10.2 12.1 84.7 9.9 37.8 6.7 11.0 5.7 3.0 11.9 7.8 30.4 8.3 10.5 18.3 40.0 171.1 13.3 14.6 10.7 14.0 54.5 42.0 8.0 13.0 14.4 8.4 43.0 6.4 89.3 6.6 1.1 9.4 7.3 9.1 14.2 6.7 7.8 2.6 13.5 14.4 12.3 2.0 12.3 20.8 6.8 11.6 20.2 19.5 4.4 0.1 15.8 35.4 10.1 2.2 158.9 5.8 9.3 0.9 72.5 19.3 21.0 0.6 20.0 1.4 13.5 4.4 3.4 34.1 39.5 51.0 37.5 0.3 6.3 120.9 16.8 19.1 5.0 3.1 9.1 15.4 2.1 47.1 51.6 171.2 30.7 13.4 43.7 55.9 13.0 26.8 19.0 11.0 0.2 63.8 33.3 7.4 5.6 14.0 55.0 1.0 5.3 3.8 13.4 44.4 11.3 19.3 7.3 39.1 31.6 76.3 34.1 90.4 31.0 77.4 18.2 0.0 1.8 1.4 6.3 1.1 10.9 1.8 11.7 10.0 3.3 3.9 8.6 5.9 0.1 13.7 0.4 1.2 5.0 4.2 9.6 10.7 10.2 12.1 8.3 10.5 14.6 10.7 14.4 14.2 13.5 11.6 16.1 778.8 305.6 15.7 14.5 11.7 9.2 35.9 5.2 2.6 42.8 13.1 21.3 4.3 23.9 5.5 4.2 19.2 14.9 20.3 11.7 1.8 0.7 17.7 5.2 19.8 24.0 46.7 6.6 32.7 217.5 17.4 4.1 40.9 3.8 32.4 5.7 26.1 42.9 3.3 1.5 74.1 6.1 29.8 79.0 0.7 1.2 28.9 28.4 60.9 10.8 5.2 9.2 5.0 1.7 11.8 26.2 1.2 56.0 9.6 2.1 17.7 2.9 1.6 6.6 2.6 8.8 2.3 6.0 2.1 7.0 60.6 23.6 31.0 64.3 6.8 SLC44A3 "CTL3, MGC45474" ENSG00000143036 "Solute carrier family 44 member 3" Q8N4M1 1 94820342-94895246 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 18 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 35.9;RPTEC TERT1: 101.4;RT4: 69.5" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in all" HPA047433 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047433: AB_2680046" "unprognostic (8.06e-2)" "unprognostic (7.65e-2)" "unprognostic (4.63e-3)" "unprognostic (3.57e-2)" "unprognostic (1.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.14e-1)" "unprognostic (4.03e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (5.78e-2)" "unprognostic (2.44e-2)" "prognostic favorable (7.63e-5)" "unprognostic (9.09e-2)" "unprognostic (8.28e-2)" "unprognostic (5.95e-2)" "unprognostic (3.31e-3)" 2.2 8.8 15.7 6.2 15.3 0.1 8.1 17.9 16.9 8.8 14.0 31.5 26.1 7.2 6.6 9.4 8.0 10.9 3.9 14.8 17.0 29.3 6.3 10.3 0.8 20.7 16.4 1.7 27.0 5.2 15.0 3.4 16.4 10.8 35.4 4.3 23.4 7.7 0.2 6.0 28.0 2.8 17.6 0.9 29.3 2.5 15.7 4.9 5.2 0.6 2.2 22.1 6.5 18.3 23.4 3.2 0.8 0.0 2.5 3.2 15.9 0.4 3.4 0.8 3.7 21.4 5.8 0.0 15.4 0.4 6.9 7.7 3.5 5.5 1.4 0.0 4.1 0.0 1.2 1.7 1.1 0.0 0.0 9.9 5.1 1.6 0.0 6.3 0.4 0.0 0.0 0.0 1.4 3.4 0.0 0.3 1.0 35.9 0.8 1.8 0.7 1.3 101.4 69.5 10.4 17.0 1.0 10.8 7.8 7.3 6.2 0.7 0.0 0.5 3.5 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 15.3 17.9 16.9 14.8 17.0 20.7 16.4 16.4 17.6 15.7 18.3 0.4 25.6 6.7 26.1 0.6 3.1 27.8 14.6 4.0 0.7 15.6 8.3 5.7 37.1 22.7 12.9 0.0 15.9 0.1 18.2 15.6 33.4 32.5 12.8 3.2 1.3 16.3 0.0 1.4 27.8 0.8 3.8 16.3 22.5 1.3 5.3 0.7 2.1 1.3 0.0 4.6 32.2 20.3 0.3 0.4 5.3 5.0 0.8 5.4 2.8 1.0 17.0 0.0 5.5 2.0 38.3 36.5 10.9 0.0 12.9 22.8 38.6 11.4 0.2 0.0 9.6 3.4 0.1 0.2 10.2 3.8 6.7 0.8 4.1 42.8 30.3 SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.2;testis: 40.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Cytotrophoblasts: 32.8;Distal enterocytes: 18.8;Glandular and luminal cells: 21.3;Paneth cells: 21.7;Proximal enterocytes: 35.5;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 42.1;OE19: 31.8;RT4: 12.3;SK-BR-3: 15.4;T-47d: 20.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049391: AB_2680743, HPA059078: AB_2732630" "unprognostic (4.53e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (9.03e-3)" "unprognostic (2.12e-3)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (4.36e-2)" "unprognostic (4.39e-3)" "unprognostic (4.82e-2)" "unprognostic (2.04e-3)" "prognostic favorable (5.51e-6)" "unprognostic (3.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" 2.1 0.2 11.0 1.5 8.9 0.4 2.6 9.5 11.4 2.3 5.5 11.5 14.4 2.0 2.0 4.9 1.8 2.6 5.7 9.0 11.1 9.4 0.1 1.2 0.4 12.9 9.8 0.9 1.6 0.2 0.3 4.3 12.3 8.0 7.1 0.6 6.1 4.0 0.6 1.8 19.2 1.7 9.8 0.2 5.6 40.1 12.5 0.1 0.5 0.9 0.8 4.9 2.5 9.7 6.6 2.2 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 4.6 42.1 0.0 7.0 0.0 0.6 6.9 0.0 6.0 0.0 0.0 0.0 0.8 0.7 0.3 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.6 31.8 4.5 0.0 0.0 1.1 0.0 12.3 0.1 0.2 7.2 15.4 0.1 0.8 20.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 2.1 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.8 0.5 0.1 0.3 0.1 0.2 11.0 8.9 9.5 11.4 9.0 11.1 12.9 9.8 12.3 9.8 12.5 9.7 3.8 9.6 3.1 0.0 0.1 0.6 2.2 5.3 1.8 0.4 3.2 2.4 0.7 4.3 5.3 23.9 2.1 32.8 0.0 18.8 1.9 6.6 1.1 8.9 1.1 10.8 0.0 0.0 0.1 2.0 0.9 0.4 4.6 21.3 0.0 5.9 0.0 0.0 2.6 0.0 0.0 6.0 6.1 0.0 1.3 3.2 0.9 0.2 1.8 2.8 0.0 0.0 0.0 0.0 0.0 5.2 21.7 0.4 0.1 4.3 35.5 0.1 2.4 0.1 0.0 0.4 0.6 0.6 0.8 2.3 1.1 52.1 0.2 1.3 10.8 5.8 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SMIM10L2A "LED, LINC00086, LINC0086, MGC39606, NCRNA00086" ENSG00000178947 "Small integral membrane protein 10 like 2A" P0DMW4 X 135421944-135428075 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "adrenal gland: 30.3;brain: 28.2;epididymis: 14.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Distal tubular cells: 7.9;Granulosa cells: 8.4;Proximal tubular cells: 12.4;Rod photoreceptor cells: 6.6;Theca cells: 16.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.1;CACO-2: 2.6;HAP1: 10.3;hTCEpi: 5.4" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.22e-2)" "unprognostic (4.72e-2)" "unprognostic (4.50e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (8.62e-3)" "unprognostic (5.83e-2)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (9.55e-3)" "unprognostic (1.36e-1)" "prognostic favorable (8.28e-8)" "unprognostic (5.29e-2)" "unprognostic (3.26e-1)" "unprognostic (7.37e-3)" "unprognostic (2.28e-2)" 0.8 30.3 17.7 0.4 20.1 0.1 1.9 8.9 24.4 2.0 3.9 0.9 0.2 1.5 14.4 1.4 2.3 0.6 3.4 19.3 28.2 5.8 0.2 2.1 0.5 14.5 16.2 4.7 3.1 4.6 3.9 0.3 21.1 2.1 0.3 5.1 2.8 1.8 0.3 2.3 0.6 0.8 10.5 3.1 1.4 5.4 18.4 0.4 3.6 0.5 0.5 0.8 1.4 14.6 0.0 0.1 0.2 5.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.8 0.1 1.9 0.0 10.3 1.3 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.0 0.4 0.4 5.4 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 0.0 1.0 0.5 2.4 0.0 0.0 0.0 1.5 0.1 0.3 0.9 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 20.1 8.9 24.4 19.3 28.2 14.5 16.2 21.1 10.5 18.4 14.6 0.9 0.0 3.3 0.0 0.0 0.0 1.0 0.0 4.6 6.5 1.6 5.7 3.8 2.8 0.0 5.5 0.0 0.0 0.0 0.0 7.9 0.7 0.4 0.8 0.6 1.8 1.2 0.0 0.0 0.4 0.0 0.7 0.0 1.0 1.3 8.4 3.3 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.4 0.1 12.4 0.0 6.6 0.0 1.2 0.6 1.1 0.4 1.3 0.0 0.3 0.3 16.3 0.1 0.7 SMIM30 LINC00998 ENSG00000214194 "Small integral membrane protein 30" A4D0T7 7 113116718-113118560 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 126.9;Distal tubular cells: 414.8;Hofbauer cells: 243.9;Proximal tubular cells: 396.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.25e-1)" "unprognostic (1.73e-3)" "unprognostic (6.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.44e-3)" "unprognostic (3.89e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.25e-2)" "unprognostic (5.00e-3)" "unprognostic (7.07e-3)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.46e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-1)" "unprognostic (1.35e-1)" 44.6 53.2 40.8 26.8 41.5 12.2 47.2 41.4 57.8 37.2 40.8 33.3 32.3 30.6 70.9 39.5 30.5 37.4 205.3 40.7 42.7 83.7 57.6 40.0 38.5 42.8 40.0 26.9 41.6 83.9 26.3 29.4 42.5 37.6 35.6 43.5 47.8 30.0 142.5 20.8 27.6 39.0 42.5 41.4 39.4 19.7 41.0 30.2 60.0 149.6 31.8 50.6 21.5 44.8 48.0 24.1 56.3 49.6 100.8 159.8 0.2 57.3 95.0 60.5 94.0 25.1 82.7 57.4 69.5 72.0 104.5 29.9 55.8 126.5 146.8 37.9 113.3 130.3 32.7 42.9 66.8 179.2 0.4 120.8 120.1 91.6 46.8 111.0 95.7 60.6 176.1 52.4 199.6 24.7 76.3 196.4 58.6 72.6 66.0 47.7 136.2 156.9 118.8 63.9 85.1 61.8 43.1 85.6 140.2 97.5 57.5 117.4 55.1 96.8 49.6 110.9 86.2 77.6 102.6 205.3 126.9 161.0 138.0 2.0 15.8 12.5 16.1 17.6 17.9 19.6 18.3 16.9 25.2 17.0 17.2 17.5 0.6 19.7 14.1 36.5 23.2 16.7 40.8 41.5 41.4 57.8 40.7 42.7 42.8 40.0 42.5 42.5 41.0 44.8 32.6 51.3 68.9 0.0 10.4 0.0 0.0 0.0 0.0 0.0 77.4 42.7 0.0 0.0 32.8 126.9 0.0 76.2 8.2 0.0 414.8 102.3 0.0 51.5 37.8 27.7 0.0 0.0 0.0 69.8 61.8 20.7 0.0 43.5 32.8 27.0 0.0 0.0 243.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 44.5 0.0 0.0 0.0 0.0 83.7 0.0 0.0 1.3 0.0 0.0 396.3 32.8 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 41.6 11.0 70.8 0.0 0.0 SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 149.8;Leydig cells: 321.8;Peritubular cells: 769.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.1;EFO-21: 2.8;RPMI-8226: 11.3;RPTEC TERT1: 3.8;SuSa: 9.1" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" 67.8 14.0 10.6 13.0 12.7 0.0 61.0 10.8 16.2 82.1 42.3 44.1 21.4 164.0 147.2 53.1 119.6 100.8 57.2 10.6 11.3 13.0 4.0 14.7 14.7 11.8 11.8 124.1 25.2 12.2 4.5 18.8 11.9 31.0 24.9 2.8 17.1 54.6 42.1 28.9 27.8 76.5 10.2 4.4 144.7 44.2 12.2 10.9 43.5 54.8 11.1 68.7 21.8 10.0 2.4 0.0 8.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.4 1.0 0.0 0.0 0.0 0.0 11.3 3.8 0.0 1.7 0.3 0.0 0.3 0.1 9.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 12.7 10.8 16.2 10.6 11.3 11.8 11.8 11.9 10.2 12.2 10.0 8.1 0.0 1.7 0.7 0.0 11.1 8.0 0.0 1.2 7.1 12.5 12.1 7.7 0.0 1.8 11.0 0.0 2.5 0.0 3.6 0.0 0.0 2.6 40.3 42.3 11.0 19.7 0.0 0.5 0.0 1.7 149.8 1.1 58.4 0.0 17.2 3.3 0.0 1.2 0.0 9.7 4.5 0.0 0.0 3.9 17.2 321.8 2.9 3.6 6.5 0.0 0.4 0.0 2.0 0.1 0.1 0.4 769.2 0.1 6.7 2.0 0.0 2.2 0.8 46.0 14.7 63.3 3.9 5.1 0.8 2.7 2.6 1.7 17.3 47.4 1.1 SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "heart muscle: 757.5;skeletal muscle: 1183.4;tongue: 1097.5" "Cell type enriched" "Detected in some" 22 "Cardiomyocytes: 807.6" "Group enriched" "Detected in many" 4 "head and neck cancer: 7.2;stomach cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "GAMG: 23.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077360 Approved "Plasma membrane" NA NA 62000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA077360: AB_2732342" "unprognostic (7.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.39e-2)" "unprognostic (7.46e-2)" "unprognostic (5.27e-1)" "unprognostic (1.96e-2)" "unprognostic (3.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (2.82e-1)" "unprognostic (8.38e-2)" 0.2 0.1 2.6 0.5 2.4 0.1 1.1 3.6 3.8 0.3 0.9 25.6 0.7 0.4 0.0 20.0 0.7 0.5 757.5 1.6 4.1 0.1 1.2 0.5 0.2 1.7 3.3 1.1 0.2 0.0 0.2 0.0 1.5 11.1 3.4 1.7 17.8 0.7 1183.4 0.5 4.1 12.6 1.3 0.1 7.2 0.2 5.3 1.5 0.2 1097.5 0.1 3.2 0.2 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 3.6 3.8 1.6 4.1 1.7 3.3 1.5 1.3 5.3 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 807.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.6 0.0 0.0 16.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 35.6 9.5 0.1 0.3 0.0 0.0 0.3 0.1 2.1 0.1 0.0 SMTNL1 CHASM ENSG00000214872 "Smoothelin like 1" A8MU46 11 57542641-57550274 "Predicted intracellular proteins" "Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "skeletal muscle: 711.3;tongue: 192.9" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.6;U-266/84: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.35e-2)" "unprognostic (3.90e-1)" "unprognostic (1.10e-1)" "unprognostic (1.79e-3)" "unprognostic (3.09e-1)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (8.41e-2)" "unprognostic (1.41e-1)" "unprognostic (3.53e-3)" "unprognostic (4.04e-2)" "unprognostic (2.68e-2)" "unprognostic (1.04e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" "unprognostic (4.49e-1)" "unprognostic (1.44e-2)" 0.4 0.2 0.7 0.9 0.1 2.3 0.4 0.2 0.3 0.4 0.0 0.2 0.3 0.3 0.0 8.8 0.5 0.3 0.3 0.2 0.2 0.2 0.8 0.9 0.8 2.5 0.6 0.5 0.1 0.0 0.5 0.1 0.5 1.6 0.0 0.6 6.1 0.0 711.3 0.3 0.5 0.0 1.3 1.1 0.2 0.5 0.9 0.0 0.4 192.9 0.0 0.2 0.4 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.1 0.7 0.3 0.2 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.6 1.0 0.0 0.1 0.4 0.0 0.6 0.3 0.7 0.4 0.4 0.4 0.2 0.3 0.5 0.2 0.3 0.6 0.4 1.1 0.2 0.5 0.2 0.2 0.1 0.7 0.1 0.2 0.3 0.2 0.2 2.5 0.6 0.5 1.3 0.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SNAI1 "SLUGH2, SNA, SNAH, SNAIL, SNAIL1" ENSG00000124216 "Snail family transcriptional repressor 1" O95863 20 49982980-49988886 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.3" "Cell type enhanced" "Detected in many" "Adipocytes: 191.3;Endothelial cells: 54.4;Extravillous trophoblasts: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.2" "Cell line enhanced" "Detected in many" "SiHa: 28.1;TIME: 39.3;WM-115: 25.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 7.0" "CAB005883, HPA056831, HPA069985, CAB078687" Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB005883: AB_443967, CAB078687: AB_2665847, HPA056831: AB_2732606, HPA069985: AB_2732146" "unprognostic (4.60e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (2.60e-2)" "unprognostic (1.15e-2)" "unprognostic (4.22e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (3.34e-3)" "unprognostic (9.85e-3)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (2.63e-7)" "unprognostic (3.75e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (8.82e-7)" "unprognostic (1.88e-2)" 30.3 12.0 2.5 4.4 2.3 4.5 16.8 2.7 2.8 6.1 2.7 5.1 1.0 7.0 0.7 2.7 9.6 16.5 16.0 2.2 3.8 8.3 5.2 16.7 2.1 4.5 2.7 2.4 5.1 1.3 6.5 7.2 2.6 4.1 0.8 0.3 3.9 2.4 2.3 4.6 3.3 3.1 2.4 9.7 5.9 3.9 4.2 0.8 15.4 1.3 0.7 9.4 4.6 3.0 1.2 0.9 5.4 0.7 1.6 1.0 10.9 4.7 5.8 0.9 0.6 8.9 1.4 0.7 12.6 8.4 5.6 0.1 1.6 0.0 0.5 0.1 1.1 0.6 2.0 5.4 13.6 1.5 4.3 3.1 0.3 2.0 0.0 14.3 14.0 0.7 7.0 0.2 0.0 2.0 0.1 1.6 7.2 0.8 3.8 2.5 1.4 0.8 6.4 0.0 2.3 5.6 28.1 7.1 1.2 4.6 1.4 6.5 39.3 0.0 6.8 0.0 0.1 0.2 0.1 7.5 2.3 2.1 25.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.5 2.3 2.7 2.8 2.2 3.8 4.5 2.7 2.6 2.4 4.2 3.0 191.3 0.0 5.3 0.3 11.8 5.2 2.4 0.5 5.2 0.6 18.6 37.0 4.5 2.8 3.8 0.0 0.0 8.3 29.7 2.8 0.0 1.5 3.0 5.8 18.6 54.4 1.8 0.0 0.6 0.2 79.9 31.7 5.6 8.7 1.3 1.0 17.5 0.3 8.0 3.3 0.4 4.5 2.0 6.4 40.3 0.8 5.6 35.6 5.4 0.0 1.0 0.8 0.0 0.0 0.7 4.7 1.6 14.3 2.2 1.6 1.4 0.2 1.0 0.4 6.6 7.6 17.5 1.4 3.8 7.2 4.8 14.0 12.2 7.2 3.0 0.6 SNCG "BCSG1, persyn, SR" ENSG00000173267 "Synuclein gamma" O76070 10 86958599-86963258 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 268.3;brain: 411.2" "Cell type enhanced" "Detected in many" "Adipocytes: 164.9;Breast myoepithelial cells: 156.1;Endothelial cells: 143.3;Hepatic stellate cells: 206.0;Smooth muscle cells: 234.3;Urothelial cells: 358.3" "Group enriched" "Detected in all" 8 "ovarian cancer: 84.1;urothelial cancer: 301.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 748.2;RT4: 483.5;T-47d: 151.7;TIME: 160.9" "Region enhanced" "Detected in all" "pons and medulla: 279.9" "Low region specificity" "Detected in many" "CAB001452, HPA014404, CAB040581, CAB080022" Enhanced Supported NA NA 23000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001452: AB_564020, CAB040581: , CAB080022: , HPA014404: AB_1857715" "unprognostic (2.06e-1)" "unprognostic (2.58e-1)" "unprognostic (6.87e-3)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (4.76e-3)" "unprognostic (8.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-3)" "unprognostic (3.75e-1)" "prognostic unfavorable (2.29e-8)" "prognostic unfavorable (7.15e-4)" "unprognostic (2.35e-1)" "unprognostic (2.36e-2)" "unprognostic (3.77e-3)" 208.2 268.3 215.6 11.9 150.8 0.0 98.1 199.9 313.3 33.3 44.0 27.0 9.2 22.9 15.1 25.4 64.5 12.7 31.7 190.2 387.7 22.3 4.3 13.9 11.6 411.2 276.4 42.1 5.3 3.3 11.1 11.9 357.8 36.6 4.9 52.7 22.9 101.6 14.6 28.6 18.8 10.1 155.3 64.2 16.4 5.4 304.7 9.0 20.3 13.7 25.6 204.8 38.9 148.8 2.6 6.8 0.7 1.1 0.3 3.9 0.7 0.8 0.0 0.0 0.0 1.1 748.2 0.0 22.6 1.4 0.0 71.0 0.0 3.4 0.0 0.1 1.4 3.6 109.6 2.0 1.4 0.0 1.8 2.8 55.5 0.0 0.6 0.2 49.8 0.0 5.3 0.0 0.0 0.6 0.2 0.4 11.3 0.0 0.4 0.0 0.4 0.3 0.2 483.5 0.1 0.0 6.5 8.7 0.9 1.0 151.7 0.3 160.9 1.1 3.7 0.3 0.0 0.2 0.0 0.0 0.8 3.6 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 215.6 150.8 199.9 313.3 190.2 387.7 411.2 276.4 357.8 155.3 304.7 148.8 164.9 0.0 0.0 7.5 1.5 28.8 65.9 16.3 11.4 32.2 61.1 156.1 1.9 8.6 14.6 55.2 6.2 19.4 2.8 0.1 125.2 3.6 0.6 0.4 0.8 143.3 0.0 2.7 9.9 1.1 0.6 14.2 0.5 0.6 0.0 0.1 206.0 0.8 5.5 87.5 28.0 0.0 20.3 1.8 27.3 3.7 59.0 2.2 23.2 6.5 0.9 66.4 0.0 4.5 7.5 4.7 2.2 9.8 0.0 14.2 0.3 1.3 2.4 109.3 92.1 2.5 234.3 0.6 0.7 2.6 19.7 6.2 2.7 16.9 0.0 358.3 SNX20 "SLIC-1, SLIC1" ENSG00000167208 "Sorting nexin 20" Q7Z614 16 50666300-50681353 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.0;lymphoid tissue: 33.2" "Cell type enhanced" "Detected in some" "B-cells: 15.3;Cardiomyocytes: 16.4;dendritic cells: 23.7;Hofbauer cells: 17.6;Kupffer cells: 17.2;Langerhans cells: 25.2;Macrophages: 19.3;monocytes: 26.1;NK-cells: 24.7;T-cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 29.7;HMC-1: 78.5;NB-4: 48.0;RPMI-8226: 20.6;THP-1: 21.3;U-266/70: 25.7;U-937: 28.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043649 Uncertain Uncertain Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA043649: AB_10965697" "unprognostic (1.53e-2)" "prognostic favorable (9.07e-4)" "unprognostic (5.58e-2)" "unprognostic (5.06e-3)" "unprognostic (9.03e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.97e-1)" "unprognostic (1.26e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.00e-6)" "unprognostic (3.24e-1)" "unprognostic (3.37e-2)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" 2.3 1.0 1.5 20.0 1.5 18.0 1.1 1.8 1.7 1.1 1.5 2.7 2.9 1.0 0.6 1.6 1.0 4.0 0.8 1.3 1.8 0.8 2.2 7.7 27.8 3.4 2.1 0.6 0.5 0.4 0.5 2.7 2.5 1.1 3.6 0.3 1.9 0.7 0.8 2.4 6.1 2.7 2.1 19.2 3.7 0.5 2.6 33.2 0.9 1.1 27.0 6.1 0.7 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.7 0.0 5.2 0.0 0.0 0.0 7.4 78.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 48.0 0.0 0.0 0.0 2.4 0.2 20.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.2 0.0 0.0 0.1 0.0 25.7 14.3 6.5 0.0 28.4 0.0 306.6 66.9 208.0 41.6 118.3 52.2 22.6 73.8 50.9 123.4 22.6 56.1 38.9 62.3 51.3 147.5 34.3 137.5 81.8 1.5 1.5 1.8 1.7 1.3 1.8 3.4 2.1 2.5 2.1 2.6 2.9 0.2 0.0 0.0 0.3 15.3 0.8 0.0 0.0 0.0 0.2 0.3 0.6 16.4 2.8 1.3 0.0 0.0 0.1 23.7 0.0 0.0 0.0 0.1 0.3 0.1 1.5 0.0 6.5 0.0 0.0 0.2 0.5 0.5 0.1 5.1 0.0 1.1 0.4 17.6 1.7 0.0 0.0 0.0 17.2 25.2 0.0 0.0 19.3 0.0 0.0 26.1 0.1 24.7 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.1 0.0 0.1 13.1 0.5 0.5 0.2 0.1 0.0 0.6 0.4 21.3 0.1 0.2 0.0 SORCS1 ENSG00000108018 "Sortilin related VPS10 domain containing receptor 1" Q8WY21 10 106573663-107164534 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;thyroid gland: 11.0" "Group enriched" "Detected in some" 7 "Excitatory neurons: 522.2;Inhibitory neurons: 179.7;Oligodendrocyte precursor cells: 381.5" "Cancer enhanced" "Detected in some" "melanoma: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "RH-30: 80.8;SH-SY5Y: 104.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011948 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA011948: AB_1857366" "unprognostic (5.86e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-2)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (1.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.52e-2)" "unprognostic (5.58e-2)" "unprognostic (6.82e-3)" "unprognostic (5.81e-2)" "unprognostic (6.48e-4)" "unprognostic (2.51e-2)" "unprognostic (8.89e-3)" "unprognostic (2.22e-1)" "unprognostic (2.69e-4)" 0.6 3.1 3.0 1.9 6.2 0.0 1.3 0.0 10.3 2.5 0.0 9.4 0.7 1.1 0.3 0.9 1.6 1.1 3.1 5.4 5.8 4.7 0.1 0.1 1.0 0.6 4.5 0.7 1.6 0.0 0.9 0.0 2.7 2.2 1.9 9.6 1.1 2.5 0.3 1.5 3.6 1.4 0.5 0.8 2.5 1.2 5.8 1.0 11.0 1.7 1.5 3.6 2.8 6.6 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 80.8 0.1 0.0 0.0 0.0 104.9 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 6.2 0.0 10.3 5.4 5.8 0.6 4.5 2.7 0.5 5.8 6.6 0.0 0.0 0.5 7.2 0.0 0.6 0.0 0.0 1.2 2.0 0.1 0.5 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 16.6 0.1 4.9 0.2 0.0 0.0 522.2 0.0 0.0 3.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 1.7 179.7 0.0 0.0 0.3 0.3 5.2 0.0 0.2 1.8 26.2 0.0 49.1 0.0 381.5 10.0 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 2.1 0.0 1.0 0.3 0.2 1.9 0.2 0.1 0.0 0.3 0.0 0.0 0.0 SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 107.1;Bipolar cells: 70.3;Excitatory neurons: 41.4;Muller glia cells: 33.0;Oligodendrocytes: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 7.6;HaCaT: 19.6;HMC-1: 14.5;RPMI-8226: 9.1;SiHa: 14.1;THP-1: 8.4;U-937: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" 2.4 1.1 13.4 3.4 18.3 1.7 1.6 11.6 15.9 8.5 0.0 4.5 1.4 4.7 3.8 2.2 3.3 3.6 2.0 12.1 11.3 9.0 4.6 4.4 0.8 18.6 17.6 5.8 0.7 0.0 2.7 0.2 14.7 5.2 1.1 12.9 1.0 2.4 1.1 1.8 2.6 6.2 11.3 0.4 1.6 1.6 14.1 3.1 3.1 1.2 1.2 3.0 3.7 22.9 0.8 1.1 1.3 0.2 0.1 0.0 0.0 0.2 0.1 1.6 0.4 0.2 0.6 0.0 7.6 5.0 1.3 19.6 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.3 0.2 0.0 14.5 0.2 4.3 6.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 0.0 0.9 0.0 1.6 9.1 0.2 0.0 0.8 0.7 14.1 0.0 0.0 0.8 0.0 8.4 0.0 4.9 1.4 0.0 0.1 0.0 0.0 0.0 1.6 8.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 18.3 11.6 15.9 12.1 11.3 18.6 17.6 14.7 11.3 14.1 22.9 0.1 3.2 11.3 107.1 0.0 0.1 0.3 4.6 0.0 70.3 0.1 2.4 2.0 0.0 6.9 5.5 0.0 0.0 0.3 0.0 0.0 0.2 2.2 0.4 0.4 0.3 0.0 0.0 41.4 0.0 0.0 5.0 0.0 0.9 0.0 5.4 0.4 1.6 0.2 1.7 24.3 0.0 2.0 0.3 0.0 11.6 12.8 0.4 1.8 8.4 0.1 33.0 1.0 8.0 76.2 1.1 0.0 7.9 0.1 0.4 0.4 1.4 2.0 2.7 0.0 0.9 1.0 0.1 0.3 0.0 0.4 0.0 0.3 1.5 0.0 0.6 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 127.4" "Group enriched" "Detected in some" 9 "Muller glia cells: 156.1;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 66.0" "Cancer enriched" "Detected in many" 6 "glioma: 46.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA041640: AB_10964357, HPA058665: AB_2683792" "unprognostic (1.40e-2)" "unprognostic (2.56e-3)" "unprognostic (1.59e-1)" "unprognostic (3.10e-2)" "unprognostic (4.58e-2)" "unprognostic (7.16e-3)" "unprognostic (6.05e-3)" "unprognostic (3.01e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "unprognostic (4.53e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-3)" "unprognostic (8.50e-2)" "unprognostic (6.18e-2)" "unprognostic (5.47e-1)" "unprognostic (9.09e-2)" 0.9 0.5 58.3 0.9 90.4 0.1 1.7 66.7 71.8 1.3 23.6 3.1 0.1 0.4 0.1 0.4 0.6 0.5 4.1 54.0 57.9 0.7 0.2 0.3 2.0 73.6 79.8 0.3 1.0 0.1 1.2 0.4 64.9 1.2 0.6 14.8 8.3 0.4 0.8 5.4 1.8 0.2 58.7 1.0 0.9 2.5 71.2 0.4 0.5 0.6 2.3 1.4 1.6 127.4 0.0 0.6 2.2 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.4 5.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 3.3 1.8 0.2 0.0 114.7 4.5 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 58.3 90.4 66.7 71.8 54.0 57.9 73.6 79.8 64.9 58.7 71.2 127.4 1.5 0.0 0.0 10.1 0.2 0.4 0.5 0.0 0.0 1.8 8.7 10.4 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.6 2.6 0.0 0.0 4.6 0.2 0.1 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.3 0.5 3.4 0.3 1.8 3.7 0.6 156.1 0.0 64.3 66.0 0.1 0.3 1.9 0.5 1.9 0.0 0.0 0.0 8.0 0.0 9.9 0.9 0.0 3.9 0.4 1.0 0.0 0.9 0.1 0.9 0.3 SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.7" "Cell type enhanced" "Detected in many" "B-cells: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 99.3" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA058554: AB_2683754" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-4)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (9.44e-2)" "unprognostic (9.68e-2)" "unprognostic (1.46e-2)" "unprognostic (4.11e-3)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.38e-1)" "unprognostic (2.66e-2)" "unprognostic (2.99e-3)" "unprognostic (9.50e-3)" 14.0 7.3 8.4 38.5 10.3 29.8 11.8 9.4 10.8 11.6 11.5 12.6 11.9 10.5 7.9 9.2 9.6 18.0 8.1 8.1 10.3 11.9 14.8 21.0 53.7 15.3 10.9 16.5 7.9 9.7 5.3 17.5 11.6 9.6 14.0 2.0 17.0 7.6 5.7 7.8 17.6 13.4 12.1 49.8 12.9 3.1 10.9 35.7 7.4 8.4 50.1 18.9 9.3 12.3 8.3 4.4 2.7 4.7 14.2 23.6 8.3 14.8 30.8 70.3 99.3 0.2 12.7 34.5 13.8 15.8 67.0 5.1 9.0 23.0 25.7 30.5 6.0 14.9 6.2 8.9 14.5 22.1 17.1 32.7 11.8 20.8 27.4 13.2 25.3 23.6 5.3 12.1 20.6 4.9 33.0 43.5 8.6 4.2 5.1 20.1 25.4 12.8 56.2 11.1 0.5 5.7 5.7 12.7 32.7 0.9 9.6 18.5 18.8 12.9 7.9 3.2 7.5 12.9 4.6 16.2 14.4 20.6 10.7 92.2 49.7 124.4 55.2 85.8 47.8 142.8 53.5 50.5 44.1 135.8 54.1 58.7 268.6 56.9 143.4 84.4 70.7 48.5 8.4 10.3 9.4 10.8 8.1 10.3 15.3 10.9 11.6 12.1 10.9 12.3 77.8 44.8 23.8 17.3 141.7 9.9 5.2 25.7 16.5 0.4 21.6 19.3 3.7 7.2 19.6 11.0 0.0 3.8 84.0 17.0 13.7 19.9 5.2 17.2 21.3 28.6 6.7 9.7 1.1 28.5 12.7 22.8 9.2 20.1 38.0 21.2 26.4 6.2 26.9 0.0 2.1 11.4 73.2 47.4 25.8 4.2 11.8 62.3 19.6 42.2 56.7 9.7 59.8 19.6 18.2 26.0 11.6 10.1 35.7 3.5 10.7 14.4 21.0 4.9 6.6 8.6 16.2 4.8 2.3 9.8 10.1 4.7 68.8 23.5 6.1 3.0 SPAG8 "BS-84, CT142, HSD-1, hSMP-1, SPAG3" ENSG00000137098 "Sperm associated antigen 8" Q99932 9 35808045-35812272 "Predicted intracellular proteins" "Cell cycle, Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 5.6;choroid plexus: 16.4;fallopian tube: 14.2;testis: 10.3" "Cell type enhanced" "Detected in many" "Early spermatids: 51.2;Endometrial ciliated cells: 75.7;Late spermatids: 26.5;Respiratory ciliated cells: 123.3;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "ASC diff: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068012 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA068012: AB_2685941" "unprognostic (1.01e-4)" "unprognostic (3.52e-3)" "unprognostic (6.36e-3)" "prognostic favorable (2.15e-4)" "unprognostic (2.62e-1)" "unprognostic (5.04e-2)" "unprognostic (1.65e-2)" "unprognostic (1.47e-2)" "unprognostic (1.59e-1)" "unprognostic (4.65e-2)" "unprognostic (1.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (5.41e-2)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (3.22e-3)" 0.3 0.5 0.9 0.2 0.8 0.3 0.3 0.9 1.1 1.7 16.4 0.8 0.4 0.7 1.0 0.2 14.2 0.6 1.7 1.4 0.8 0.7 0.1 1.3 0.4 3.8 5.6 1.3 0.3 1.0 2.5 0.2 2.9 0.7 0.1 0.2 0.3 0.4 0.4 0.2 0.3 0.2 2.0 0.6 0.4 10.3 1.0 0.7 1.4 0.8 0.3 0.5 0.3 1.3 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.3 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.3 0.1 0.4 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.4 0.2 0.6 0.3 0.0 0.0 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.3 0.2 1.4 0.7 0.0 0.6 0.4 0.2 0.0 0.4 0.6 1.1 0.4 0.3 0.8 0.0 0.9 0.0 0.0 1.0 0.4 0.9 0.8 0.9 1.1 1.4 0.8 3.8 5.6 2.9 2.0 1.0 1.3 1.0 0.0 1.5 8.1 1.0 0.4 1.0 6.3 0.0 4.9 0.8 1.8 3.6 0.0 10.4 5.5 8.4 0.3 1.0 0.0 1.9 0.4 51.2 75.7 1.1 1.0 3.0 0.4 4.4 0.0 0.1 1.4 0.5 1.4 1.3 0.7 1.1 0.1 1.0 3.3 4.7 0.0 8.2 0.3 0.9 26.5 1.5 1.9 0.0 1.0 1.9 5.7 0.0 3.0 7.0 0.1 0.0 1.2 0.9 0.6 0.1 1.6 123.3 8.5 0.0 1.5 4.5 58.8 3.1 0.0 0.6 0.1 1.1 1.4 0.1 0.3 SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 68.3;testis: 28.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2341.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.5;BEWO: 24.4;BJ hTERT+: 15.9;HSkMC: 29.3;hTCEpi: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036854, HPA036855" Enhanced Supported Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA036854: AB_10670927, HPA036855: AB_2675352" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.27e-2)" "unprognostic (4.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "prognostic favorable (3.73e-9)" "unprognostic (4.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.01e-2)" "unprognostic (4.00e-2)" 2.1 5.0 2.4 0.7 2.2 0.0 6.3 1.3 1.0 10.7 15.6 4.1 2.1 4.2 2.0 4.6 68.3 6.7 1.8 2.5 2.7 5.3 5.4 8.0 0.3 6.8 8.3 1.8 2.0 4.5 4.9 1.9 5.5 4.2 5.6 0.1 10.1 5.6 0.8 6.6 2.2 3.1 6.0 0.6 4.9 28.8 2.6 3.2 1.2 1.3 0.9 2.8 3.4 3.8 0.0 3.8 1.8 0.0 12.7 31.5 24.4 9.3 15.9 0.6 0.7 0.0 1.5 0.0 0.0 12.3 0.2 0.3 0.1 7.1 0.3 0.0 1.1 0.0 0.0 8.0 11.2 0.0 0.0 29.3 28.7 1.0 4.5 5.1 6.9 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 2.0 1.0 0.0 0.0 9.7 0.0 0.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.2 1.3 1.0 2.5 2.7 6.8 8.3 5.5 6.0 2.6 3.8 0.3 9.6 3.0 0.3 0.0 5.2 8.5 9.4 8.6 0.0 6.0 6.7 2.2 8.6 15.1 0.0 0.0 1.7 0.3 1.8 1.9 1.2 561.1 124.6 1.8 1.2 1.8 0.0 1.7 2.6 1.8 4.3 11.2 4.7 2.5 1.9 1.4 3.4 0.3 0.0 0.5 1.6 6.1 0.6 1.6 2341.5 10.8 1.1 0.0 2.8 0.1 0.0 0.0 0.5 0.1 2.0 2.7 10.9 0.0 5.1 1.9 7.4 141.4 0.0 0.0 1.8 3.9 13.9 7.1 7.1 7.5 0.8 0.2 2.5 4.3 6.8 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPRED2 "FLJ21897, FLJ31917, Spred-2" ENSG00000198369 "Sprouty related EVH1 domain containing 2" Q7Z698 2 65310851-65432637 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 108.7;Excitatory neurons: 138.5;Inhibitory neurons: 122.4;Oligodendrocyte precursor cells: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 1.9;plasmacytoid DC: 4.2" "Group enriched" "Detected in many" 4 "dendritic cells: 4.2;NK-cells: 1.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038256, HPA064394" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA038256: , HPA064394: AB_2732712" "unprognostic (1.49e-1)" "unprognostic (5.95e-3)" "unprognostic (3.46e-2)" "unprognostic (4.40e-3)" "unprognostic (8.94e-2)" "unprognostic (1.63e-1)" "unprognostic (2.90e-2)" "unprognostic (9.94e-2)" "unprognostic (9.07e-2)" "unprognostic (4.25e-1)" "unprognostic (5.05e-2)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (7.21e-3)" "unprognostic (5.43e-2)" 23.9 11.4 12.0 9.7 15.3 7.0 21.7 11.8 22.8 13.5 5.6 16.5 14.9 16.5 8.6 10.9 13.3 13.2 14.7 14.4 11.4 13.7 24.8 18.4 14.0 14.4 12.5 14.0 18.0 16.7 11.5 15.8 11.2 12.3 16.1 10.9 15.9 10.8 8.0 11.3 13.7 11.5 11.1 8.5 19.8 7.4 13.3 28.7 17.9 13.9 15.4 15.5 14.0 12.7 60.4 32.9 32.2 32.4 41.1 40.9 22.2 16.1 25.2 10.9 14.5 43.4 16.4 41.2 9.2 20.8 29.2 18.7 18.2 37.2 21.9 52.3 11.6 9.7 9.1 45.2 21.0 25.7 18.8 33.1 22.2 37.2 36.9 22.9 6.9 24.9 39.1 16.9 17.7 40.9 22.6 26.7 16.1 43.4 35.4 17.1 28.6 24.2 34.1 52.3 13.1 45.1 18.1 14.8 44.2 20.1 15.1 23.7 11.4 27.6 35.8 23.8 27.4 33.2 13.8 73.7 44.7 27.1 54.2 0.0 0.2 0.0 0.6 0.7 0.0 0.0 0.1 0.5 0.4 0.0 0.1 0.1 0.6 1.9 0.3 4.2 0.0 0.7 12.0 15.3 11.8 22.8 14.4 11.4 14.4 12.5 11.2 11.1 13.3 12.7 49.7 19.2 16.0 108.7 1.8 39.9 29.0 12.0 41.5 17.8 22.7 17.7 7.5 14.3 6.6 9.2 6.2 11.0 3.3 32.0 13.7 11.0 1.5 16.8 11.4 18.6 11.4 1.7 138.5 8.6 8.4 21.0 14.8 35.0 1.3 2.8 13.9 14.1 6.7 25.2 122.4 24.1 8.2 7.5 67.6 4.1 17.1 10.2 19.6 68.4 26.0 7.9 0.0 124.1 23.2 13.9 21.5 12.4 0.5 23.4 17.1 7.4 7.2 9.8 26.3 17.0 17.4 3.9 10.4 16.6 16.8 3.0 3.8 4.7 10.9 24.0 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STAU2 39K2 ENSG00000040341 "Staufen double-stranded RNA binding protein 2" Q9NUL3 8 73420369-73747708 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 278.9;Inhibitory neurons: 298.3;Oligodendrocyte precursor cells: 157.8;Oligodendrocytes: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 152.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019155, CAB020836" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB020836: , HPA019155: AB_1857565" "unprognostic (5.75e-2)" "unprognostic (3.39e-1)" "unprognostic (2.31e-3)" "unprognostic (2.47e-2)" "unprognostic (3.76e-1)" "unprognostic (6.27e-2)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (6.36e-2)" "unprognostic (4.01e-2)" "unprognostic (3.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.62e-3)" "unprognostic (9.94e-2)" "unprognostic (2.98e-1)" "unprognostic (6.44e-3)" "unprognostic (4.25e-2)" 20.2 22.7 24.8 15.8 30.5 24.6 17.8 35.0 39.6 15.3 5.5 17.6 14.9 18.2 19.0 35.1 16.6 24.2 70.6 34.8 22.8 29.5 25.7 17.3 19.3 25.3 25.6 18.2 16.1 29.6 12.5 17.6 25.0 20.9 18.6 34.6 20.5 20.8 110.6 15.0 20.8 23.4 16.2 16.7 16.3 16.8 20.7 35.0 22.9 110.0 22.0 20.8 14.2 35.3 34.7 40.7 63.5 34.5 35.5 25.2 19.3 30.4 27.5 27.1 35.4 15.6 36.0 55.1 31.5 23.9 24.3 27.2 44.5 29.2 39.1 56.1 21.2 74.7 19.4 25.5 18.6 28.4 25.8 18.1 21.6 23.2 15.1 55.8 54.8 48.2 50.5 24.2 36.8 22.6 152.7 22.5 31.4 57.5 26.8 44.9 29.6 46.3 57.6 38.1 24.0 40.2 16.4 43.1 27.4 46.8 51.2 33.3 43.4 26.3 46.0 26.2 22.7 39.4 41.7 51.8 29.3 42.3 22.1 24.4 18.0 42.8 28.6 17.9 21.5 15.7 19.0 24.3 18.4 17.9 16.6 21.7 30.8 44.4 22.8 25.1 26.0 12.8 24.8 30.5 35.0 39.6 34.8 22.8 25.3 25.6 25.0 16.2 20.7 35.3 20.4 9.6 31.1 120.8 22.5 10.6 15.4 16.7 8.6 29.1 24.6 11.8 75.7 21.5 40.7 20.2 41.7 18.4 27.1 22.5 43.0 22.7 22.0 18.6 11.6 26.2 29.9 14.7 278.9 21.7 10.0 20.2 21.4 25.5 20.3 21.8 38.2 58.0 16.1 28.6 298.3 17.6 18.3 24.1 16.8 32.2 9.0 22.5 16.0 129.3 16.9 26.9 43.3 157.8 149.9 17.6 16.5 9.4 20.2 10.9 102.1 37.6 27.6 22.2 0.0 15.8 21.8 12.5 13.8 22.1 19.2 12.2 21.6 20.5 16.1 18.5 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STIM2 ENSG00000109689 "Stromal interaction molecule 2" Q9P246 4 26857601-27025381 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 84.2" "Cell type enhanced" "Detected in all" "Astrocytes: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 187.7;U-698: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036933, CAB037196, HPA057511" Supported NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 14: REH - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "CAB037196: AB_1841195, HPA036933: AB_2675391, HPA057511: AB_2683453" "unprognostic (7.09e-2)" "unprognostic (8.80e-3)" "unprognostic (1.60e-3)" "unprognostic (2.58e-2)" "unprognostic (2.83e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (3.97e-5)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "prognostic favorable (5.01e-4)" "unprognostic (6.81e-2)" "unprognostic (1.45e-2)" "unprognostic (2.60e-2)" "unprognostic (7.55e-2)" "unprognostic (3.17e-1)" "unprognostic (2.17e-3)" 11.2 7.5 11.5 16.9 14.3 17.3 11.6 11.1 14.3 11.0 84.2 11.5 16.6 10.8 22.5 6.2 12.3 19.8 6.9 17.7 12.4 13.0 9.9 15.1 25.4 12.7 12.2 18.8 14.2 8.4 13.7 10.3 12.5 13.9 14.4 18.8 12.9 7.3 8.2 13.9 15.0 10.2 9.7 22.1 14.9 7.4 13.7 20.8 10.6 6.5 23.4 13.9 7.7 14.3 10.0 14.1 13.9 17.5 14.7 9.2 12.7 24.0 7.7 12.6 15.1 12.4 34.4 44.5 13.6 9.4 13.1 11.9 10.4 28.3 13.4 13.4 16.2 13.0 26.3 11.9 11.7 23.3 13.5 12.1 13.7 16.9 8.8 16.3 15.4 17.7 14.1 8.8 31.0 11.9 17.2 22.9 15.2 20.8 18.9 187.7 26.0 10.9 10.6 22.3 24.3 8.8 16.9 12.3 6.6 9.9 7.6 19.8 16.3 17.1 11.1 11.8 15.7 23.7 20.8 90.6 18.4 24.8 28.0 12.9 1.7 1.4 3.9 1.4 2.6 4.1 4.2 3.3 1.3 4.8 4.5 3.5 3.0 1.8 6.5 5.0 2.2 1.3 11.5 14.3 11.1 14.3 17.7 12.4 12.7 12.2 12.5 9.7 13.7 14.3 55.8 12.8 26.9 123.7 57.1 16.4 14.1 42.4 17.6 39.0 18.7 16.3 8.8 22.8 30.6 33.1 81.3 11.9 62.7 17.3 13.7 10.5 9.8 18.0 19.9 49.3 45.7 14.9 69.9 20.1 6.9 20.2 26.0 14.7 36.8 32.4 32.2 11.2 7.4 30.3 68.1 30.8 46.8 20.4 16.2 8.3 15.2 29.2 8.8 58.1 18.9 19.2 65.9 101.0 87.5 12.7 15.9 7.2 37.1 10.9 19.4 5.1 112.4 61.1 19.7 22.5 18.3 19.9 24.0 7.8 15.5 4.9 48.3 37.0 14.4 12.9 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in many" "Early spermatids: 108.2;Late spermatids: 39.3;Microglial cells: 27.2;Oligodendrocyte precursor cells: 169.4" "Cancer enhanced" "Detected in many" "renal cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 27.5;HUVEC TERT2: 27.5;REH: 25.2;U-2197: 43.8;WM-115: 112.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 3.5 0.3 2.3 1.2 7.8 1.5 4.3 1.9 2.3 3.3 1.5 1.1 0.5 3.5 0.3 1.2 1.3 1.4 0.4 2.1 4.5 15.0 0.1 0.9 1.8 3.7 3.9 0.6 1.8 0.3 0.4 3.2 3.7 0.6 1.1 0.8 1.0 0.9 1.3 2.4 1.1 2.5 3.6 0.2 6.0 4.5 3.5 19.5 1.7 1.7 1.0 3.1 1.5 3.6 0.0 14.0 0.8 0.0 0.6 1.0 0.0 9.7 1.1 6.3 0.2 0.1 0.0 0.0 2.1 19.7 27.5 0.1 1.5 0.0 2.3 0.0 0.0 0.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.2 27.5 1.4 0.0 0.1 3.4 0.0 0.0 2.0 4.1 0.0 0.0 25.2 0.1 0.0 6.2 0.0 0.4 0.0 0.0 0.1 8.5 0.6 0.0 0.0 7.1 0.2 2.8 43.8 0.0 0.9 0.1 0.0 0.1 0.0 112.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 7.8 1.9 2.3 2.1 4.5 3.7 3.9 3.7 3.6 3.5 3.6 3.6 0.0 1.1 1.6 0.0 2.3 0.2 0.0 0.0 0.0 4.2 1.7 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 17.6 1.1 108.2 0.2 0.1 3.2 0.0 0.0 3.7 0.0 0.1 5.5 4.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 14.4 0.0 0.0 0.0 1.2 39.3 1.5 1.1 5.4 27.2 0.5 0.0 0.0 169.4 1.3 0.4 0.0 1.2 0.0 0.1 0.0 18.9 0.0 0.0 0.0 0.6 0.4 1.2 5.5 0.0 1.0 0.0 0.2 0.4 0.0 0.1 STMN3 SCLIP ENSG00000197457 "Stathmin 3" Q9NZ72 20 63639705-63657682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 291.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.5;Granulosa cells: 254.2;Horizontal cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 5 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "AN3-CA: 125.1;MOLT-4: 142.0;REH: 143.8;SCLC-21H: 192.5;SH-SY5Y: 146.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012947 Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Cytosol "HPA012947: AB_1857606" "unprognostic (7.59e-2)" "unprognostic (4.36e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-1)" "unprognostic (3.60e-2)" "unprognostic (6.30e-2)" "unprognostic (2.75e-1)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.65e-3)" "unprognostic (7.52e-2)" "unprognostic (2.52e-3)" "unprognostic (2.73e-2)" "unprognostic (9.87e-2)" "unprognostic (4.08e-2)" "unprognostic (9.08e-3)" 23.4 49.7 188.4 21.3 197.6 11.4 20.0 112.5 291.7 29.2 16.6 26.5 5.5 30.0 5.0 11.6 27.9 10.9 17.1 215.0 162.0 24.8 3.7 23.6 25.8 259.6 158.1 50.5 16.4 17.5 102.2 10.0 266.1 24.3 5.2 38.8 11.7 12.7 4.3 20.2 24.8 14.7 100.8 48.2 15.1 9.0 159.3 43.5 63.9 3.7 12.4 21.9 19.0 179.9 10.4 11.6 74.4 125.1 1.9 7.3 5.1 12.0 0.4 35.8 16.8 73.6 13.7 0.5 36.3 4.6 2.0 68.6 52.2 1.3 11.1 5.2 14.0 5.1 17.0 27.6 9.9 3.9 42.0 15.3 0.3 11.5 2.9 1.5 1.3 34.4 98.8 2.2 9.6 11.7 142.0 17.7 76.5 2.4 81.7 143.8 12.1 58.0 60.9 2.0 192.5 146.6 5.7 3.4 14.9 5.9 2.1 25.9 1.9 0.8 20.4 0.8 2.6 4.9 10.4 3.6 2.1 14.3 48.8 1.1 0.0 1.1 2.5 0.1 2.7 0.2 5.2 4.5 0.1 0.6 6.2 5.3 0.1 0.0 0.1 1.1 0.9 2.0 188.4 197.6 112.5 291.7 215.0 162.0 259.6 158.1 266.1 100.8 159.3 179.9 5.8 6.4 2.5 16.3 17.1 8.2 6.9 11.9 8.6 108.5 4.7 14.7 2.3 4.3 3.2 3.7 52.1 11.7 13.4 1.1 13.7 4.0 10.0 1.6 17.9 7.8 37.2 4.6 56.9 2.5 4.0 25.4 2.0 2.7 4.5 254.2 6.8 0.0 2.3 109.4 67.1 0.6 4.1 2.2 7.6 18.8 30.1 3.5 7.2 7.5 4.6 37.2 16.5 21.1 11.3 2.2 0.1 35.7 5.3 4.5 0.1 5.0 0.8 44.5 13.1 3.0 20.9 3.3 6.7 1.6 4.3 8.8 28.6 51.0 0.6 2.7 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 85.0;granulocytes: 90.3;Langerhans cells: 271.6;Macrophages: 158.0;monocytes: 85.5;Suprabasal keratinocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cell line enhanced" "Detected in some" "HDLM-2: 17.2;Karpas-707: 10.1;RH-30: 6.9;TIME: 8.3;U-266/70: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" 25.1 4.4 0.6 5.8 0.6 56.5 14.5 0.6 1.1 1.9 0.7 2.8 1.0 1.4 0.3 5.1 2.6 2.1 7.3 0.7 0.8 3.6 3.1 21.3 5.5 1.0 0.7 0.9 1.1 0.6 2.1 2.4 0.9 1.3 0.9 0.2 2.1 0.3 2.5 8.2 3.3 1.9 0.8 14.1 2.0 1.1 0.9 1.8 7.5 0.9 3.5 4.0 3.2 1.1 0.4 0.1 0.1 3.9 0.2 0.3 0.6 0.4 0.3 0.4 0.7 0.1 0.4 0.1 0.4 0.6 0.7 0.6 0.0 0.1 0.2 17.2 0.6 3.0 0.6 0.1 1.0 0.9 0.5 0.0 0.0 0.2 0.1 0.2 4.3 0.8 0.1 10.1 0.5 0.2 0.4 0.9 0.0 0.0 0.3 0.1 6.9 0.6 0.0 1.9 0.2 0.1 1.2 0.1 1.7 0.3 0.1 3.8 8.3 0.2 1.0 0.4 0.3 11.6 4.6 0.1 0.2 2.1 0.4 22.6 68.4 43.5 6.0 81.1 3.8 1.4 2.7 5.1 25.4 2.4 1.0 3.0 81.7 3.2 87.0 2.7 8.3 43.9 0.6 0.6 0.6 1.1 0.7 0.8 1.0 0.7 0.9 0.8 0.9 1.1 41.9 54.5 10.7 0.0 16.6 85.0 11.3 6.3 3.4 0.0 11.1 4.6 4.5 4.3 6.6 1.8 0.0 0.9 38.1 0.1 0.0 6.4 0.4 3.7 0.7 23.7 3.5 6.1 0.1 2.6 5.7 11.2 0.5 5.0 90.3 0.2 8.2 1.4 30.1 0.0 0.1 0.4 2.0 73.7 271.6 1.2 0.6 158.0 44.4 2.8 85.5 0.0 21.6 0.0 0.1 6.1 3.3 0.0 63.1 14.4 0.0 0.1 10.7 0.1 0.0 46.6 9.7 3.0 3.8 11.2 154.6 28.0 36.6 3.2 0.6 33.3 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656348-47786616 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 205.8;Oligodendrocyte precursor cells: 247.8;Theca cells: 265.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basophil: 27.2;classical monocyte: 19.6;intermediate monocyte: 17.2;myeloid DC: 21.3;neutrophil: 31.5;non-classical monocyte: 9.0;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 84 "dendritic cells: 27.1;granulocytes: 31.5;monocytes: 19.6" "Cell line enhanced" "Detected in many" "EFO-21: 338.0;HaCaT: 230.1;HBEC3-KT: 259.4;hTCEpi: 815.1;MCF7: 695.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Intracellular and membrane" NA NA 340000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "HPA002325: AB_1080126" "unprognostic (4.06e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (4.39e-1)" "unprognostic (8.99e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (1.81e-2)" "unprognostic (3.04e-2)" "unprognostic (1.53e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (7.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.14e-3)" 57.5 12.4 25.8 42.7 30.3 11.5 43.5 21.0 30.7 113.3 20.5 48.0 29.4 152.6 9.8 77.5 73.5 64.3 35.6 45.8 41.4 57.2 38.7 16.5 27.8 56.8 51.1 139.3 9.8 7.1 40.4 26.3 57.1 23.3 43.9 13.6 34.0 22.4 14.7 32.7 26.9 86.5 22.3 15.1 20.6 21.3 30.1 18.2 42.7 22.5 25.1 36.6 62.6 22.6 0.5 20.6 93.4 0.1 19.2 2.3 8.5 16.3 0.0 1.7 2.9 36.7 48.7 3.7 338.0 17.0 5.5 230.1 27.2 259.4 0.7 0.4 20.0 0.0 24.2 82.7 17.4 0.1 4.9 104.1 815.1 1.7 11.2 0.2 18.4 0.0 0.0 151.5 1.9 695.2 0.0 1.4 18.8 0.0 209.0 0.2 0.2 39.8 198.6 1.1 8.2 2.1 32.9 0.3 0.1 122.1 1.3 2.6 17.8 0.0 2.1 0.2 22.5 5.4 1.7 1.6 0.4 0.1 2.8 27.2 19.6 2.2 0.0 17.2 0.2 0.3 0.0 0.1 21.3 0.2 0.0 0.0 31.5 0.1 9.0 27.1 0.0 6.2 25.8 30.3 21.0 30.7 45.8 41.4 56.8 51.1 57.1 22.3 30.1 22.6 62.7 9.6 7.2 2.0 21.9 10.5 7.6 25.4 18.8 8.5 14.0 8.3 8.6 20.0 9.0 16.5 0.0 12.0 34.9 38.4 0.0 5.3 2.7 19.7 205.8 59.2 27.4 7.8 10.3 2.2 10.1 37.0 10.2 30.6 1.3 28.1 62.2 19.0 5.2 35.3 10.8 7.6 16.2 20.6 46.2 6.7 28.9 44.4 10.6 12.2 85.8 8.8 6.2 247.8 1.1 4.9 62.0 76.3 6.2 9.9 3.5 14.1 2.7 6.2 0.0 4.1 13.7 1.2 3.5 24.7 8.4 16.4 11.2 265.0 25.8 12.3 SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.3;Cholangiocytes: 37.1;Endothelial cells: 13.2;Granulosa cells: 15.3;Hepatic stellate cells: 17.9;Muller glia cells: 12.3;Oligodendrocyte precursor cells: 17.6" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.5;HUVEC TERT2: 10.7;SH-SY5Y: 42.0;SuSa: 11.6" "Low region specificity" "Detected in many" HPA034530 Approved Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" 6.2 2.0 15.5 1.1 16.1 0.5 5.2 16.9 17.2 21.9 12.9 3.4 1.5 11.1 8.0 2.3 9.3 27.1 10.9 13.6 18.9 18.2 3.7 10.3 1.8 18.8 27.3 27.9 2.9 1.0 5.2 13.0 20.4 6.6 2.2 8.6 1.6 8.9 3.1 0.7 3.2 5.5 18.1 1.4 2.0 1.4 19.0 5.0 4.5 6.2 1.3 3.8 5.3 15.8 0.0 0.1 9.5 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 1.2 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 42.0 0.0 0.0 0.0 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 15.5 16.1 16.9 17.2 13.6 18.9 18.8 27.3 20.4 18.1 19.0 15.8 13.3 0.0 0.5 10.4 0.0 0.3 0.7 0.0 0.0 2.0 0.4 0.3 0.7 37.1 0.0 9.2 0.0 0.3 0.0 0.0 0.0 0.3 5.9 10.9 3.1 13.2 0.0 2.7 0.6 0.2 0.1 4.9 0.0 3.8 0.0 15.3 17.9 0.0 0.9 1.7 0.5 0.0 0.0 1.3 1.0 1.1 1.5 0.4 0.0 7.5 0.1 12.3 0.0 17.6 0.4 0.1 0.0 4.5 1.4 0.7 0.0 7.7 0.0 1.0 0.0 1.4 1.8 0.6 0.7 0.0 0.4 0.3 0.2 7.2 0.0 0.2 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "heart muscle: 262.3;skeletal muscle: 279.2;tongue: 87.2" "Cell type enriched" "Detected in some" 52 "Cardiomyocytes: 665.1" "Group enriched" "Detected in some" 6 "breast cancer: 1.5;head and neck cancer: 1.4;prostate cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 4.1;HSkMC: 3.2;RH-30: 3.0;SK-BR-3: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced Supported "Nuclear speckles,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Cell Junctions, Cytosol" "HPA055192: AB_2682732, HPA057142: AB_2683348" "unprognostic (2.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.20e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-2)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-1)" 0.1 0.5 0.7 0.1 0.7 0.3 3.6 0.8 0.9 0.4 0.1 0.0 0.1 0.1 0.1 11.8 0.1 0.1 262.3 0.7 0.5 0.1 0.1 1.2 0.2 0.7 0.6 0.2 0.4 0.0 0.1 0.6 0.5 3.1 0.0 0.4 4.8 0.0 279.2 0.3 0.0 0.0 0.5 0.2 0.1 0.3 0.6 0.1 0.2 87.2 0.2 0.0 1.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.6 0.1 0.0 4.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 3.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.1 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.7 0.7 0.8 0.9 0.7 0.5 0.7 0.6 0.5 0.5 0.6 0.7 0.5 3.2 0.0 0.3 0.9 1.5 1.4 0.0 2.2 1.9 1.0 0.8 665.1 0.0 0.7 0.0 2.1 0.2 0.5 0.0 0.0 0.0 2.6 0.1 0.4 5.0 0.0 0.0 0.3 0.0 0.2 12.6 0.0 0.3 1.3 0.3 0.0 0.4 0.2 0.0 0.9 0.0 0.0 0.6 2.1 1.1 0.9 0.8 1.8 1.0 0.3 0.4 0.0 1.5 1.1 0.0 0.0 0.4 0.3 0.9 0.0 0.2 0.7 1.2 0.0 12.0 5.2 0.8 1.3 0.4 0.4 0.0 0.7 0.2 0.0 1.0 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 212.0;Microglial cells: 159.3;Oligodendrocyte precursor cells: 193.5;Oligodendrocytes: 223.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036750: AB_10670241" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.91e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" 9.1 5.9 9.7 3.9 14.0 0.2 7.8 15.8 7.5 10.2 8.1 9.2 6.4 10.9 2.0 12.7 5.8 7.5 22.1 13.0 15.8 6.6 4.4 12.6 3.3 18.4 13.6 6.3 5.9 5.9 3.5 13.4 18.1 7.8 7.0 12.0 7.1 4.4 2.7 20.5 6.5 12.9 11.9 5.0 5.9 1.9 21.1 3.6 10.8 4.3 4.8 8.6 6.8 20.0 8.7 7.4 18.4 14.3 16.7 7.1 9.0 6.6 13.9 6.6 10.4 8.0 9.5 0.0 22.6 21.2 5.0 18.7 5.9 26.1 8.4 0.0 13.7 5.6 11.8 1.5 19.7 0.7 14.3 11.0 21.3 12.4 23.1 30.1 35.8 8.5 1.4 39.8 11.1 3.9 5.5 0.0 2.4 9.8 6.7 0.7 10.0 12.9 15.2 34.9 2.8 18.9 14.5 6.6 34.9 11.4 7.2 5.6 33.8 14.7 8.6 3.1 6.1 19.7 14.5 0.0 8.2 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 14.0 15.8 7.5 13.0 15.8 18.4 13.6 18.1 11.9 21.1 20.0 42.1 28.9 17.1 34.9 0.2 48.9 13.5 21.7 46.7 30.1 19.3 16.9 64.7 15.7 23.5 11.0 6.2 2.9 0.9 18.9 3.9 13.3 1.1 11.1 12.1 48.3 0.0 4.2 9.9 12.5 3.8 16.0 33.1 11.7 17.2 47.6 35.3 8.7 2.0 212.0 54.7 16.6 10.2 2.8 10.3 1.7 10.5 1.7 24.9 159.3 0.6 48.6 1.0 193.5 223.7 13.4 22.7 4.9 1.6 14.4 10.5 4.9 12.5 4.9 13.1 11.6 27.5 0.5 2.1 38.6 42.1 2.1 2.5 14.6 14.9 17.3 TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;pancreas: 12.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.9;Inhibitory neurons: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 25.9;OE19: 11.9;RPMI-8226: 12.6;RT4: 12.8;SCLC-21H: 26.5;SK-BR-3: 16.7;T-47d: 14.5" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" 1.5 1.1 2.0 1.0 2.7 0.3 2.3 4.9 10.1 3.0 1.4 1.4 1.8 1.4 1.8 0.6 1.5 1.8 0.6 5.3 1.7 2.2 1.2 2.3 0.4 6.8 1.8 0.9 12.0 2.4 6.4 0.6 6.9 3.0 1.5 2.2 6.8 2.7 0.3 0.8 1.6 0.9 2.0 1.9 3.9 1.9 2.0 0.3 1.5 0.3 0.3 3.3 1.3 3.8 5.1 1.0 0.5 0.3 0.1 0.6 0.7 0.0 0.0 0.1 0.0 4.3 1.8 0.1 0.9 0.1 0.3 0.1 5.3 0.2 0.0 0.0 3.8 0.3 1.4 0.1 0.0 4.0 0.8 0.3 0.1 0.0 0.0 0.6 3.8 1.2 0.0 2.0 0.3 25.9 0.0 0.6 1.1 11.9 5.2 0.2 0.1 12.6 0.9 12.8 26.5 1.8 1.4 16.7 0.3 0.3 14.5 1.4 4.2 0.0 0.9 0.9 2.5 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 2.7 4.9 10.1 5.3 1.7 6.8 1.8 6.9 2.0 2.0 3.8 5.1 0.0 6.3 4.9 0.6 0.9 4.6 0.9 0.0 9.3 7.2 3.8 0.6 5.7 4.5 3.7 8.4 0.7 1.5 2.5 9.8 3.9 14.2 2.2 0.8 6.5 0.0 0.0 30.9 4.9 0.3 0.7 3.6 4.2 8.9 0.8 1.8 0.3 1.6 0.0 42.8 6.4 6.1 4.0 6.2 1.9 0.3 3.0 5.4 12.2 1.2 2.6 0.0 1.5 2.0 2.7 4.9 0.0 0.6 9.1 3.9 2.3 1.8 0.6 0.0 0.6 1.0 3.7 3.0 0.3 1.4 0.1 0.8 0.4 4.4 8.7 TCAIM "C3orf23, DKFZp313N0621, TOAG-1" ENSG00000179152 "T cell activation inhibitor, mitochondrial" Q8N3R3 3 44338119-44409451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 42.9" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.15e-1)" "unprognostic (9.21e-2)" "unprognostic (1.98e-1)" "unprognostic (4.24e-1)" "unprognostic (1.82e-1)" "unprognostic (8.55e-2)" "unprognostic (1.93e-3)" "unprognostic (5.07e-3)" "unprognostic (5.60e-2)" "prognostic favorable (2.19e-7)" "unprognostic (4.03e-1)" "unprognostic (1.49e-1)" "unprognostic (4.65e-2)" "prognostic favorable (2.81e-4)" 8.6 8.5 7.9 6.7 8.6 4.8 6.6 12.0 10.5 5.9 8.7 9.6 8.2 6.7 8.4 10.1 6.4 9.7 19.4 7.0 8.8 24.2 42.9 9.3 6.9 9.8 9.1 8.1 5.7 11.4 3.5 9.2 9.8 9.9 9.8 10.3 4.7 5.9 22.0 7.7 9.2 8.7 8.7 7.2 9.4 5.6 9.1 8.4 7.4 18.9 7.9 9.9 4.2 10.9 15.5 7.5 8.3 10.6 13.5 10.8 17.3 14.8 17.4 15.7 16.5 7.0 35.6 22.0 10.8 10.0 11.4 7.1 8.0 16.5 17.4 9.2 8.8 15.5 10.4 16.5 23.5 25.9 14.4 12.7 33.0 15.9 17.9 14.9 21.3 22.1 19.2 12.5 16.2 10.8 25.2 13.2 7.8 17.4 17.5 5.0 9.1 16.8 36.6 24.2 8.3 20.3 16.5 22.6 24.1 14.4 17.1 15.3 18.1 9.4 11.2 24.7 22.4 8.4 16.5 16.1 21.2 20.9 16.1 14.8 7.9 10.6 3.6 10.0 4.2 2.3 4.7 3.6 10.3 3.7 3.8 5.5 3.6 3.6 10.1 5.5 9.4 4.0 7.9 8.6 12.0 10.5 7.0 8.8 9.8 9.1 9.8 8.7 9.1 10.9 12.5 9.6 16.1 38.5 7.4 10.3 9.3 12.2 12.0 18.9 11.1 8.3 30.1 24.3 10.5 14.7 12.5 13.6 14.5 12.0 60.7 23.6 3.3 10.3 7.8 11.6 6.0 7.2 55.8 20.9 21.0 7.5 12.2 17.7 21.0 15.1 15.0 47.7 20.0 25.2 90.4 17.1 12.2 18.8 10.1 2.0 8.7 17.6 7.2 20.6 16.0 17.1 9.2 42.7 47.1 25.6 14.7 4.9 7.4 10.8 11.7 46.2 11.4 13.1 13.1 8.1 12.8 6.2 11.0 16.8 9.5 13.4 8.2 14.6 17.3 13.4 TCEA2 TFIIS ENSG00000171703 "Transcription elongation factor A2" Q15560 20 64049836-64072347 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 173.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043836 Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Centrosome "HPA043836: AB_2678694" "unprognostic (6.51e-2)" "unprognostic (2.02e-1)" "unprognostic (3.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.80e-1)" "unprognostic (4.91e-3)" "unprognostic (2.38e-1)" "unprognostic (2.91e-1)" "unprognostic (1.65e-3)" "unprognostic (9.03e-3)" "unprognostic (2.49e-2)" "unprognostic (9.67e-2)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (2.70e-1)" "unprognostic (2.28e-1)" "unprognostic (3.79e-1)" 32.9 31.0 63.0 9.7 62.9 8.5 32.1 58.0 105.9 45.8 32.9 43.7 6.2 42.7 13.2 14.2 42.0 16.7 40.1 63.4 61.6 39.7 56.9 23.9 12.8 70.5 61.8 55.8 19.3 31.0 57.7 17.5 71.8 39.2 3.2 12.1 22.2 25.3 41.6 24.7 21.6 14.0 54.2 30.7 25.8 91.9 62.5 15.4 38.5 14.0 6.0 38.2 31.6 62.8 17.1 18.7 29.7 50.2 26.5 15.8 11.5 16.8 20.0 31.4 15.0 11.4 30.5 19.4 38.6 21.8 18.0 45.8 12.3 15.5 6.1 12.0 21.8 7.2 37.3 29.1 38.8 8.3 9.9 24.9 13.4 8.1 10.3 43.9 21.6 24.4 12.8 35.5 9.7 41.5 34.4 41.5 18.4 22.8 44.7 32.1 21.7 51.0 17.1 12.2 28.5 48.4 18.0 12.0 46.3 9.8 34.0 21.3 30.7 56.2 28.3 31.5 10.2 40.2 28.4 10.7 50.1 9.4 11.5 1.6 1.0 3.2 2.2 1.2 0.9 7.5 1.9 1.6 1.3 2.8 3.3 2.1 0.5 2.6 1.9 2.1 3.9 1.0 63.0 62.9 58.0 105.9 63.4 61.6 70.5 61.8 71.8 54.2 62.5 62.8 43.3 0.0 3.1 20.5 34.5 22.6 38.3 17.6 38.7 54.1 44.9 64.0 31.0 30.0 11.5 71.7 27.1 27.6 13.6 0.6 107.6 35.6 123.6 30.8 44.3 40.7 19.1 5.7 21.9 16.0 13.4 43.9 13.7 21.0 2.5 62.8 47.5 47.6 17.4 65.6 19.0 2.8 16.2 16.8 23.7 173.1 51.9 20.5 62.2 7.5 18.4 123.3 10.3 8.5 17.0 24.3 2.1 49.2 14.7 31.2 11.6 115.6 16.1 37.1 26.3 43.2 48.9 126.1 39.0 13.2 20.2 20.8 18.7 42.3 3.6 25.9 TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 55.2;Horizontal cells: 48.8;Leydig cells: 43.8;Muller glia cells: 88.3;Oligodendrocytes: 46.5;Peritubular cells: 39.1;Skeletal myocytes: 48.3;Smooth muscle cells: 38.7" "Cancer enriched" "Detected in many" 10 "glioma: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 83.8;BJ hTERT+ SV40 Large T+ RasG12V: 75.1;GAMG: 115.3;hTEC/SVTERT24-B: 83.8;LHCN-M2: 72.0;SCLC-21H: 210.1;U-87 MG: 78.9" "Low region specificity" "Detected in many" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA051507: AB_2681512, HPA065080: AB_2685419" "unprognostic (1.09e-2)" "unprognostic (4.36e-2)" "unprognostic (5.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (4.52e-2)" "unprognostic (2.17e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.18e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.62e-1)" "unprognostic (2.28e-2)" "unprognostic (1.35e-3)" 7.7 27.9 72.4 4.3 73.0 0.0 9.1 75.1 126.3 26.3 40.5 18.6 4.0 48.2 18.3 5.5 17.0 11.9 14.0 72.1 84.5 5.0 2.4 6.1 2.3 80.8 77.5 29.0 1.2 1.1 37.4 2.1 82.3 12.3 7.8 23.5 3.5 13.2 3.7 1.8 8.3 29.9 74.5 5.8 6.5 3.1 77.2 5.1 3.8 9.9 1.4 9.7 15.6 96.0 0.0 0.0 83.8 0.0 36.3 55.5 15.0 12.0 61.9 26.4 75.1 0.0 0.0 0.0 0.0 12.9 115.3 0.0 0.0 1.8 45.5 0.0 0.8 0.3 0.0 0.0 18.2 0.0 0.1 46.6 0.0 83.8 0.1 0.0 27.6 0.0 0.5 0.2 72.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 53.1 0.3 0.0 0.0 210.1 56.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 38.8 1.4 0.6 0.0 0.0 0.0 0.0 78.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 72.4 73.0 75.1 126.3 72.1 84.5 80.8 77.5 82.3 74.5 77.2 96.0 4.8 0.0 1.3 5.9 0.0 2.5 5.3 0.3 1.2 36.4 0.9 19.2 13.6 0.0 0.7 3.7 4.2 1.4 0.1 0.0 5.9 0.2 0.2 1.0 42.9 5.2 0.0 0.0 21.2 0.0 0.7 55.2 0.0 0.7 0.0 19.2 1.8 0.0 0.7 48.8 26.5 0.0 0.0 0.0 4.0 1.8 43.8 0.6 8.8 4.7 0.0 88.3 0.0 19.6 46.5 0.3 0.0 39.1 0.1 1.1 0.0 2.1 0.0 12.9 13.1 48.3 38.7 3.0 1.5 0.8 3.1 0.3 0.5 5.1 0.0 0.8 TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 11.6;Endometrial ciliated cells: 12.0;Exocrine glandular cells: 12.7;Extravillous trophoblasts: 26.6;Hofbauer cells: 14.6;monocytes: 11.9;Pancreatic endocrine cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 66.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: AB_2676320, HPA039050: AB_10670918" "unprognostic (8.06e-2)" "unprognostic (1.06e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-3)" "unprognostic (8.73e-3)" "unprognostic (2.88e-1)" "unprognostic (1.17e-1)" "unprognostic (6.18e-3)" 5.1 1.6 5.2 4.9 5.5 6.8 4.7 4.1 7.8 4.3 0.5 5.5 5.1 3.8 1.0 6.8 4.6 1.8 4.3 5.8 3.0 4.0 5.4 4.9 5.4 7.0 3.5 2.5 3.0 1.0 5.3 1.6 4.2 4.2 1.6 0.5 4.3 2.3 2.3 8.2 5.4 1.0 3.1 6.8 5.9 4.9 3.6 4.5 5.7 0.5 3.1 3.9 4.5 5.3 17.2 38.9 9.2 13.5 0.8 1.5 24.5 13.4 5.0 15.9 14.7 14.0 31.2 25.6 27.2 2.2 6.2 43.5 3.2 14.0 3.0 29.0 16.0 6.5 22.8 13.3 0.6 12.9 17.9 0.3 4.6 10.6 3.5 2.0 6.4 23.2 10.5 31.2 2.5 66.7 26.9 29.6 11.9 14.6 41.8 21.9 13.8 17.9 4.5 14.3 25.7 15.5 13.7 15.8 9.8 2.0 26.0 12.6 7.8 10.9 18.4 33.4 22.4 17.8 8.2 15.7 13.9 14.8 18.0 0.0 0.5 0.6 0.5 0.9 0.4 0.1 0.8 1.4 0.7 0.3 0.6 0.1 0.1 0.0 0.8 2.4 0.6 0.2 5.2 5.5 4.1 7.8 5.8 3.0 7.0 3.5 4.2 3.1 3.6 5.3 4.8 3.2 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.9 5.3 0.0 0.0 0.6 1.8 0.0 8.0 10.1 0.0 3.9 11.6 0.0 12.0 3.0 4.0 0.0 0.0 0.0 12.7 26.6 3.4 0.0 7.2 0.0 8.1 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 11.9 0.0 0.0 0.0 0.0 14.7 0.0 0.0 4.7 0.0 0.0 2.0 3.6 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.0 4.2 2.5 0.0 0.0 TENM4 "KIAA1302, ODZ4, Ten-M4, TEN4" ENSG00000149256 "Teneurin transmembrane protein 4" Q6N022 11 78652829-79441030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;ovary: 16.6;parathyroid gland: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Early spermatids: 96.8;Excitatory neurons: 337.4;Inhibitory neurons: 297.7;Microglial cells: 117.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 9.1;hTERT-RPE1: 9.5;PC-3: 10.8;REH: 10.4;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "HPA019521, HPA065961" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019521: AB_2670171, HPA065961: AB_2685588" "unprognostic (2.81e-1)" "unprognostic (9.25e-2)" "unprognostic (1.64e-1)" "unprognostic (2.96e-3)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-2)" "unprognostic (1.24e-1)" "unprognostic (3.01e-1)" "unprognostic (3.79e-1)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "unprognostic (6.51e-3)" "unprognostic (5.40e-3)" "unprognostic (5.64e-2)" "unprognostic (7.07e-2)" "unprognostic (9.81e-3)" 1.9 1.4 7.5 1.0 13.4 0.0 0.7 0.3 12.6 2.5 0.0 0.5 0.1 1.3 0.2 2.0 2.1 0.4 0.4 9.0 7.5 1.5 0.0 0.4 0.5 10.9 9.2 16.6 0.3 14.0 7.1 0.1 7.9 0.4 0.3 2.6 0.5 0.2 0.4 3.3 0.3 1.0 13.0 0.3 0.5 1.6 11.8 1.9 5.8 1.0 1.2 0.5 1.5 17.8 0.0 0.0 3.4 0.0 3.7 5.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 7.8 6.7 0.0 2.1 5.0 5.3 0.0 4.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 9.1 2.3 2.5 4.5 9.5 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.0 1.8 0.3 10.8 10.4 0.0 0.0 6.4 1.1 7.1 17.4 0.0 0.0 0.0 6.2 0.0 0.1 0.5 0.1 1.2 0.1 5.9 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 13.4 0.3 12.6 9.0 7.5 10.9 9.2 7.9 13.0 11.8 17.8 0.1 0.0 0.0 134.5 0.2 0.9 0.8 3.4 17.1 7.5 0.1 0.0 1.9 4.3 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 96.8 1.1 1.7 0.3 0.0 0.0 337.4 0.0 0.2 2.6 0.0 0.8 1.3 0.8 0.0 0.0 0.1 0.0 297.7 0.0 0.0 0.6 0.4 56.6 5.3 0.7 0.0 117.1 0.4 13.9 0.0 58.3 21.3 0.0 0.0 1.9 0.0 0.4 0.0 0.4 7.0 1.0 0.0 25.1 2.8 4.8 1.0 7.3 2.0 0.1 0.1 0.3 0.0 0.6 TESPA1 "ITPRID3, KIAA0748" ENSG00000135426 "Thymocyte expressed, positive selection associated 1" A2RU30 12 54948015-54984762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.3;lymphoid tissue: 75.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 202.7;granulocytes: 120.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 247.1;HMC-1: 187.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058823, HPA079222" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA058823: AB_2683828, HPA079222: " "unprognostic (1.98e-5)" "unprognostic (3.70e-4)" "unprognostic (3.87e-4)" "unprognostic (1.13e-3)" "unprognostic (3.20e-2)" "unprognostic (4.55e-4)" "unprognostic (2.29e-3)" "unprognostic (5.34e-4)" "unprognostic (3.83e-4)" "unprognostic (1.35e-2)" "unprognostic (3.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.50e-2)" "unprognostic (4.11e-1)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" 1.3 0.5 19.6 13.9 37.6 14.5 1.7 12.0 81.3 1.9 11.9 3.7 3.0 2.3 4.8 1.9 1.3 4.8 1.0 36.6 13.2 0.8 0.9 5.8 36.4 11.6 12.2 6.9 0.9 0.7 0.6 0.5 12.1 1.5 4.8 1.0 1.4 1.1 1.4 1.0 7.5 2.1 11.4 13.5 3.9 0.9 16.1 75.2 1.1 0.6 36.4 4.0 1.1 44.2 0.2 0.4 0.6 0.4 0.7 0.7 3.2 0.0 0.7 0.2 0.3 0.0 0.4 17.5 0.2 0.7 0.6 0.4 0.7 0.4 0.3 20.0 0.6 247.1 0.8 0.3 0.6 13.6 187.7 0.5 0.4 0.4 0.7 0.5 0.0 41.5 1.0 16.3 0.4 0.4 39.1 1.5 0.5 0.2 0.2 9.3 0.3 2.7 0.6 0.9 0.5 0.2 0.6 0.1 0.5 0.7 0.2 3.6 0.3 0.4 0.4 0.2 0.2 11.1 0.4 12.0 1.7 4.0 0.4 43.1 1.4 1.6 38.3 1.3 43.5 17.9 126.0 57.5 16.0 15.0 175.8 98.8 3.1 57.2 1.5 5.6 92.6 64.5 19.6 37.6 12.0 81.3 36.6 13.2 11.6 12.2 12.1 11.4 16.1 44.2 0.7 0.0 4.3 10.1 9.9 0.5 0.0 0.0 0.0 0.0 0.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 32.4 202.7 0.0 0.0 1.3 0.0 0.1 120.1 0.0 0.4 0.5 0.1 0.0 2.5 0.0 0.0 1.3 1.6 0.0 0.9 4.6 1.8 2.8 3.3 0.0 25.7 7.1 5.1 0.0 0.0 1.2 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.3 0.0 37.0 0.8 0.1 0.0 TEX9 ENSG00000151575 "Testis expressed 9" Q8N6V9 15 56244009-56445997 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.1;Endometrial ciliated cells: 86.2;Respiratory ciliated cells: 125.6;Spermatocytes: 74.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 4.3;memory B-cell: 14.4;naive B-cell: 11.4" "Group enriched" "Detected in many" 12 "B-cells: 14.4;granulocytes: 4.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039415 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039415: AB_10672775" "unprognostic (3.27e-1)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (4.71e-3)" "unprognostic (2.34e-1)" "unprognostic (5.13e-2)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.75e-2)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "unprognostic (8.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" 1.8 6.1 4.1 4.6 3.9 3.4 10.1 7.4 3.9 8.8 17.0 3.6 11.6 5.2 8.4 4.4 28.0 5.2 1.1 3.2 4.2 10.8 1.5 4.4 6.0 9.4 8.6 5.4 5.4 14.2 9.9 1.6 4.5 4.5 4.8 18.0 10.5 3.4 1.2 5.6 8.0 2.2 5.3 3.2 12.2 16.4 6.6 3.7 17.4 1.5 10.6 2.7 1.6 5.7 7.8 7.1 15.3 13.7 3.7 10.8 2.0 1.7 6.3 4.8 5.7 1.7 6.9 15.5 7.0 1.2 8.2 6.6 6.6 7.4 5.5 1.7 7.8 9.1 6.7 5.2 1.1 3.3 1.3 5.9 13.3 5.4 4.1 6.9 0.2 11.1 5.2 1.4 2.6 4.5 6.5 1.2 7.2 13.2 3.0 2.6 7.1 5.5 15.9 4.4 24.3 9.8 8.7 4.9 5.5 11.2 14.6 3.0 0.7 20.3 5.8 6.5 6.4 2.1 16.5 11.7 8.0 1.7 3.9 4.3 0.1 0.1 0.4 0.6 0.1 14.4 0.4 0.3 0.2 11.4 0.2 0.8 0.3 0.4 0.4 0.4 0.6 0.7 4.1 3.9 7.4 3.9 3.2 4.2 9.4 8.6 4.5 5.3 6.6 5.7 1.5 6.4 7.5 38.8 21.0 4.2 7.3 13.2 20.5 6.4 11.3 11.7 0.8 5.7 23.5 11.0 12.5 1.8 0.3 2.3 21.5 15.6 89.1 86.2 5.1 3.2 7.7 5.9 14.3 7.0 0.5 5.0 17.3 4.8 1.3 5.1 1.8 0.4 1.3 1.7 20.4 3.7 16.2 0.0 2.1 40.9 4.7 2.7 3.6 4.7 1.2 6.8 1.0 14.6 15.1 4.5 5.4 3.8 15.8 3.7 12.3 21.7 125.6 37.5 0.0 4.6 6.0 74.6 36.6 6.9 2.3 0.3 1.0 6.2 6.7 4.9 TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 305.8;intestine: 355.3;salivary gland: 340.2;thyroid gland: 416.7" "Cell type enriched" "Detected in many" 10 "Intestinal goblet cells: 33890.3" "Cancer enhanced" "Detected in all" "colorectal cancer: 765.0" "Region enriched" "Detected in single" 6 "midbrain: 1.9" "Immune cell enriched" "Detected in single" 9 "eosinophil: 1.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "MCF7: 58.7;OE19: 126.6;T-47d: 27.8;TIME: 105.0" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" No NA 151000000 6500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "CAB020681: , HPA035464: AB_2674636" "unprognostic (2.84e-2)" "unprognostic (3.61e-3)" "unprognostic (1.07e-1)" "prognostic favorable (5.60e-6)" "unprognostic (1.28e-1)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (3.71e-1)" "unprognostic (6.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" "unprognostic (3.86e-2)" 11.5 5.9 0.1 27.8 0.1 2.2 26.3 0.3 0.2 305.8 0.1 355.3 208.0 2.8 0.5 22.7 49.8 82.8 3.5 0.1 0.1 5.7 6.6 9.9 3.5 0.1 1.9 3.5 6.1 0.0 1.3 0.1 0.2 9.8 305.8 0.1 340.2 1.6 0.9 6.7 290.6 8.4 0.1 23.1 7.4 0.5 0.2 1.8 416.7 1.7 0.9 3.6 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.7 0.0 0.7 0.1 126.6 12.1 0.0 9.0 0.3 0.1 0.0 16.1 0.1 0.0 1.7 0.0 0.0 27.8 0.0 105.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 1.9 0.2 0.1 0.2 0.1 36.9 16.0 25.3 0.0 15.4 41.6 15.1 196.3 3.4 0.1 804.5 444.7 21.6 919.3 595.9 22.0 0.0 0.6 3.4 2188.7 0.0 9.4 0.5 29.3 1.4 322.8 770.9 0.0 0.0 67.8 0.7 21.5 71.4 11.4 59.2 2.0 170.3 5.8 2.1 5.0 0.0 33890.3 3263.2 3.4 42.4 9.0 2.5 2.8 96.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 1855.5 7.9 6.1 73.0 2788.7 0.1 453.2 0.1 0.0 1.1 28.2 1.0 0.3 4.3 38.6 0.8 14.9 0.6 1376.3 107.7 THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 29 "Early spermatids: 297.1;Late spermatids: 1075.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 76.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 9400000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" 16.7 9.3 4.5 8.9 5.1 9.1 16.3 3.0 5.3 24.9 7.9 25.0 5.4 33.6 21.0 14.1 24.4 16.7 23.2 4.9 5.4 16.4 14.5 15.6 5.7 4.8 6.7 24.9 19.1 10.8 15.9 8.8 4.5 20.0 10.7 4.7 13.3 15.5 5.8 18.8 14.1 28.6 3.3 11.0 14.5 14.9 6.4 4.4 23.6 8.0 6.2 18.8 19.4 4.2 3.3 7.8 28.3 28.9 15.1 17.5 1.7 13.3 19.6 6.1 10.9 1.0 24.0 2.2 14.7 29.4 1.8 7.9 0.8 5.0 4.5 5.3 1.9 1.9 9.8 1.1 16.3 1.6 3.9 30.3 17.2 8.9 12.2 76.2 11.0 4.9 1.7 4.6 5.5 12.0 1.3 3.0 6.5 6.9 3.9 26.2 1.2 5.3 12.7 8.2 41.7 23.8 3.4 6.5 6.8 40.7 19.1 4.1 8.5 20.1 4.6 3.8 4.7 11.1 1.4 0.5 18.2 1.7 1.7 0.0 1.6 0.6 0.6 0.8 0.4 0.5 0.9 0.7 1.3 0.2 1.0 0.3 0.7 0.3 0.2 0.2 1.7 0.8 4.5 5.1 3.0 5.3 4.9 5.4 4.8 6.7 4.5 3.3 6.4 4.2 4.0 0.0 14.3 7.2 1.4 7.9 2.6 3.1 4.6 2.5 6.6 6.1 1.7 5.7 2.8 0.0 0.0 1.7 3.5 3.3 1.9 4.9 297.1 5.3 10.3 5.6 4.8 0.8 11.2 2.5 1.8 22.6 5.6 5.0 0.0 7.5 2.9 5.4 9.9 8.4 6.3 4.3 6.1 3.8 8.6 1075.2 23.3 3.7 10.6 0.0 1.9 1.5 1.0 0.0 3.2 3.7 2.9 10.1 1.4 2.3 2.7 3.8 2.6 3.7 0.0 11.8 8.1 20.8 4.8 3.7 5.3 1.4 2.2 2.4 3.4 2.2 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38823715-38856817 "CD markers, Enzymes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 13.6;Hofbauer cells: 7.2;Kupffer cells: 12.2;Langerhans cells: 6.6;Macrophages: 11.6;Microglial cells: 20.6;monocytes: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 13.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.3;GAMG: 13.5;RPMI-8226: 10.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA062733: AB_2684853" "unprognostic (9.82e-2)" "unprognostic (4.76e-2)" "unprognostic (3.30e-2)" "unprognostic (3.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.45e-2)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (7.62e-7)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (7.78e-2)" "unprognostic (2.12e-2)" 1.6 1.6 1.2 10.3 1.1 6.6 1.4 1.4 1.1 1.0 1.4 1.6 1.6 1.0 0.5 1.4 1.2 3.5 0.6 1.1 1.9 0.5 2.0 2.6 10.8 2.6 1.9 1.3 0.4 0.5 0.4 2.6 3.0 0.9 2.1 0.1 2.0 0.5 0.3 0.7 4.4 2.0 2.7 9.7 2.2 0.3 2.8 2.0 0.6 1.3 13.8 3.2 0.8 4.4 1.6 6.1 0.2 0.1 0.3 6.8 0.0 1.7 7.3 0.7 2.4 0.0 13.3 7.5 2.8 0.3 13.5 0.7 0.1 1.3 1.1 0.0 0.5 3.4 7.3 0.2 0.4 3.9 5.5 2.9 1.4 2.9 1.6 0.2 1.5 1.1 3.9 2.3 3.3 0.0 0.0 6.7 0.2 0.0 1.0 3.7 3.2 10.8 0.4 0.1 0.0 0.1 0.2 0.0 1.0 0.3 0.3 2.0 2.1 2.3 7.8 0.9 2.7 0.1 0.0 6.1 5.3 4.4 1.7 0.0 2.6 0.8 0.2 2.5 0.0 1.7 0.1 0.1 1.8 1.0 0.2 0.1 13.4 0.3 1.3 1.2 0.3 0.7 1.2 1.1 1.4 1.1 1.1 1.9 2.6 1.9 3.0 2.7 2.8 4.4 0.6 0.0 0.0 0.3 13.6 0.6 1.2 0.3 0.0 0.6 1.2 0.8 1.2 0.0 0.2 0.0 0.0 0.0 2.2 0.2 0.0 0.5 0.0 0.5 0.7 1.1 0.0 0.4 0.2 0.2 0.2 0.9 0.0 1.2 2.5 0.3 0.4 0.2 7.2 0.0 0.9 0.1 0.0 12.2 6.6 0.0 0.6 11.6 0.0 20.6 14.0 0.2 1.0 0.5 0.3 0.3 0.1 0.7 3.7 0.9 0.2 0.0 1.3 0.8 0.0 0.9 0.5 0.2 0.0 0.2 0.9 0.3 1.7 1.4 0.1 0.8 TMCC2 "FLJ38497, HUCEP11" ENSG00000133069 "Transmembrane and coiled-coil domain family 2" O75069 1 205227946-205285632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 88.1;brain: 47.3" "Cell type enriched" "Detected in many" 8 "Erythroid cells: 622.1" "Cancer enhanced" "Detected in many" "melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014254 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 6: Erythroid cells - Oxygen transport" "HPA014254: AB_1851326" "unprognostic (2.59e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (2.61e-2)" "unprognostic (4.18e-1)" "unprognostic (5.59e-2)" "unprognostic (2.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.53e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-5)" "unprognostic (3.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-3)" "unprognostic (3.06e-2)" "unprognostic (4.01e-1)" "unprognostic (3.43e-3)" 1.4 2.6 15.2 0.4 24.2 88.1 0.9 18.7 47.3 1.8 0.0 2.5 0.3 1.6 0.0 0.7 2.0 0.3 3.6 25.2 16.1 1.4 0.7 3.1 0.3 38.5 26.1 3.1 0.5 3.1 5.0 5.3 41.0 1.0 0.1 8.5 0.9 0.3 3.5 1.7 0.9 0.5 17.3 16.0 0.9 2.0 25.5 0.7 1.3 1.5 0.2 1.2 1.6 33.6 1.9 0.9 1.7 3.8 0.7 0.2 0.9 2.4 1.0 2.3 1.8 0.3 0.2 1.8 0.4 0.6 6.3 3.2 1.1 0.5 0.7 5.7 4.2 7.5 0.5 0.1 0.3 0.3 3.5 0.4 0.1 1.2 0.0 2.0 0.3 1.7 4.0 2.4 0.9 0.1 0.0 0.9 4.1 0.0 5.2 2.8 4.3 9.1 0.4 0.1 32.0 4.3 0.2 0.0 8.0 1.5 0.7 0.4 0.8 1.5 2.5 3.9 2.7 4.9 2.1 1.2 1.3 0.6 9.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 15.2 24.2 18.7 47.3 25.2 16.1 38.5 26.1 41.0 17.3 25.5 33.6 1.9 0.0 0.0 6.2 0.4 1.0 0.4 1.2 0.0 34.4 0.2 0.0 4.6 0.0 0.3 1.8 10.4 0.1 0.3 0.0 0.0 1.6 1.5 3.7 0.8 2.5 3.5 622.1 7.9 0.0 0.2 1.0 0.0 1.9 0.0 7.4 3.9 0.0 0.9 40.4 10.1 0.1 0.0 0.6 6.1 0.8 1.2 13.1 3.6 2.8 7.8 17.7 0.0 2.5 73.0 0.2 0.0 0.4 0.8 0.1 0.0 0.2 0.9 43.2 0.0 1.8 2.8 1.1 4.8 0.4 0.9 0.0 0.7 0.8 0.1 0.1 TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.3;prostate: 36.6;seminal vesicle: 13.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 416.1;Inhibitory neurons: 382.0;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 1337.5" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 36.9;LHCN-M2: 107.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" NA NA "Cluster 65: Brain - Ion transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" 0.3 2.3 30.2 0.1 25.8 0.0 0.3 16.0 26.6 0.1 5.8 0.9 0.6 0.0 8.1 1.2 0.1 1.7 1.8 28.5 26.9 0.0 0.0 0.1 0.0 21.5 23.5 0.2 0.0 0.0 0.3 0.0 22.4 36.6 1.5 3.3 0.1 13.3 0.3 0.2 0.6 0.1 16.6 0.0 0.9 0.7 26.3 0.0 0.2 0.6 0.1 0.8 0.5 33.3 0.0 0.9 36.9 0.0 5.6 5.8 0.1 0.1 0.7 1.8 2.2 0.0 0.0 0.0 0.0 10.3 4.5 0.0 2.3 0.0 7.1 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 15.6 0.0 2.0 10.8 9.0 0.1 0.0 0.0 0.0 107.1 0.0 0.0 0.1 2.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.2 2.8 0.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 25.8 16.0 26.6 28.5 26.9 21.5 23.5 22.4 16.6 26.3 33.3 0.1 0.0 0.0 11.8 0.0 0.1 0.1 0.0 0.0 16.6 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 416.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.6 382.0 0.5 0.0 0.0 0.7 2.3 26.4 0.0 0.0 11.2 0.0 0.6 0.0 210.6 1337.5 0.0 0.0 8.6 0.0 5.7 0.1 0.0 0.0 1.6 6.6 24.6 0.6 1.2 2.6 0.3 0.3 0.0 0.4 0.0 0.0 0.1 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 988.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" 56.0 80.2 53.0 120.2 60.3 225.1 153.3 56.7 68.2 114.9 67.0 120.0 63.5 174.7 47.8 100.1 91.7 99.6 71.2 48.0 61.0 93.2 393.7 119.2 196.4 71.2 68.6 86.8 82.5 70.7 15.8 98.5 65.1 105.2 97.1 9.2 224.0 104.1 20.4 95.6 78.8 130.6 61.3 111.2 125.5 73.3 61.5 238.6 312.3 49.7 142.9 146.8 70.7 89.8 220.5 195.8 186.9 174.8 233.5 185.6 135.8 169.7 352.0 324.4 358.1 247.9 988.1 370.2 423.9 387.9 234.5 228.3 212.3 272.9 339.4 228.4 82.5 192.0 67.8 352.3 207.5 404.1 137.4 219.1 280.7 240.1 352.3 433.9 361.8 187.8 134.3 0.9 257.7 71.8 353.0 135.4 115.8 340.3 181.1 214.7 532.0 359.3 291.3 207.9 90.7 110.5 201.8 267.6 109.9 197.2 161.3 154.0 451.9 211.3 249.4 190.5 126.6 139.4 84.3 366.6 62.0 432.7 143.2 159.7 113.3 207.0 102.6 121.8 155.3 70.1 158.8 123.8 126.1 95.3 208.6 181.7 72.4 223.9 111.0 33.7 183.8 248.7 53.0 60.3 56.7 68.2 48.0 61.0 71.2 68.6 65.1 61.3 61.5 89.8 93.3 125.0 78.1 33.0 179.3 160.3 257.1 307.3 157.6 0.7 144.9 118.4 53.9 143.0 202.8 163.7 0.0 45.8 91.8 48.2 80.3 153.7 41.3 141.1 47.6 140.0 90.5 68.3 1.0 118.8 41.1 82.2 88.2 161.4 58.9 126.6 271.3 317.6 107.1 1.7 2.2 163.1 160.7 249.6 419.9 23.6 94.1 189.8 161.9 63.7 229.4 4.7 83.4 25.6 114.0 127.8 55.1 93.3 117.8 324.2 31.0 52.9 257.0 1.1 65.7 181.9 80.2 23.1 74.9 146.3 177.2 30.4 164.8 109.4 146.3 270.2 TMEM143 FLJ10922 ENSG00000161558 "Transmembrane protein 143" Q96AN5 19 48332356-48364059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 43.6;skeletal muscle: 95.5;tongue: 61.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014476, HPA058645" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "HPA014476: AB_1858092, HPA058645: " "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (5.23e-2)" "unprognostic (2.50e-1)" "unprognostic (5.94e-2)" "unprognostic (2.11e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (4.08e-1)" "unprognostic (2.25e-1)" "unprognostic (7.29e-2)" "unprognostic (9.82e-2)" "prognostic favorable (1.53e-7)" "unprognostic (5.46e-2)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-1)" 6.5 9.0 5.2 2.6 6.0 2.7 5.2 5.3 6.8 4.9 4.3 7.2 4.5 4.3 2.5 4.6 4.5 3.2 43.6 5.2 5.4 10.4 18.1 4.3 3.7 5.5 5.5 4.7 5.7 3.7 5.1 2.7 5.5 5.3 2.7 3.3 5.6 2.6 95.5 5.8 6.8 2.2 4.7 7.7 6.8 4.2 5.7 6.2 6.4 61.2 2.3 6.2 4.3 5.9 4.6 7.4 2.3 4.2 4.5 6.3 4.7 4.2 2.5 2.9 3.7 6.3 5.9 8.6 7.5 2.8 1.4 5.2 2.3 3.0 1.6 10.6 5.2 5.2 6.3 10.1 3.6 4.1 4.8 5.8 3.7 1.5 3.7 3.3 2.4 12.9 3.8 12.5 3.1 2.6 5.9 14.8 2.9 8.7 2.5 8.6 1.4 14.2 3.9 3.4 8.6 8.5 2.5 3.1 2.1 2.6 4.4 2.9 2.9 3.5 3.9 2.6 1.6 24.3 8.2 6.5 2.9 5.4 2.8 1.9 1.2 1.4 2.2 0.7 2.7 2.1 1.7 2.1 1.5 1.5 2.6 1.5 1.0 3.4 1.2 0.6 1.3 1.3 5.2 6.0 5.3 6.8 5.2 5.4 5.5 5.5 5.5 4.7 5.7 5.9 2.3 3.2 1.1 8.1 3.7 0.3 3.0 3.4 2.8 3.3 3.2 1.8 27.0 0.0 2.0 1.8 8.4 9.5 2.8 3.7 13.7 3.5 0.7 2.0 1.4 2.2 3.0 4.8 9.8 2.4 6.1 3.3 5.6 1.3 1.3 4.6 1.4 7.5 5.5 0.0 8.7 4.4 4.1 2.1 1.0 1.3 2.5 2.6 8.8 6.5 2.5 3.9 2.1 5.5 9.9 1.2 7.1 1.2 7.6 0.9 8.5 14.6 5.3 6.7 0.0 2.5 3.1 8.7 5.5 3.1 1.0 3.7 3.6 3.4 4.3 1.2 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1171.9;monocytes: 502.3;Paneth cells: 762.4;Proximal enterocytes: 922.5;Proximal tubular cells: 976.5" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Group enriched" "Detected in some" 17 "HSkMC: 642.7;THP-1: 215.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" 120.9 49.5 48.5 190.8 50.1 13.5 77.8 50.7 65.8 74.5 43.0 251.8 167.7 25.9 25.7 50.4 81.5 197.3 208.5 45.4 58.0 356.5 1656.5 95.6 177.5 69.2 60.1 143.1 53.6 7.3 22.7 115.0 64.5 48.9 244.9 34.1 42.5 28.3 11.0 34.7 286.6 99.0 65.0 87.0 94.5 11.1 52.2 26.1 33.6 36.1 93.7 158.6 92.4 73.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 25.7 0.4 0.8 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.6 0.8 0.2 642.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.9 0.5 0.1 0.0 0.1 1.0 11.8 0.1 0.0 1.9 1.4 0.6 0.3 0.2 0.2 0.0 215.7 0.0 0.0 3.2 0.5 0.2 0.4 0.2 0.6 0.0 0.3 0.0 5.3 865.5 50.5 2.3 586.0 3.4 2.5 0.6 0.7 164.3 0.6 0.7 0.4 8.6 0.6 309.3 7.7 0.6 498.5 48.5 50.1 50.7 65.8 45.4 58.0 69.2 60.1 64.5 65.0 52.2 73.2 22.2 3.2 9.3 14.4 16.9 12.6 0.5 0.9 5.7 156.9 52.2 74.0 73.7 190.1 14.4 375.2 2.1 0.9 2.8 419.4 166.3 95.1 18.5 6.1 14.5 19.8 128.1 13.5 0.1 34.0 1.0 243.7 14.8 2.1 54.4 61.9 22.9 1171.9 92.5 6.7 0.6 252.1 46.8 98.5 44.4 12.2 43.5 190.0 16.0 8.4 502.3 87.3 1.0 7.5 0.1 65.4 762.4 3.4 1.5 2.5 922.5 976.5 11.3 17.9 0.0 6.7 34.0 4.0 3.8 1.8 15.6 2.7 9.1 0.4 263.7 2.8 TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.4;Excitatory neurons: 109.1;Inhibitory neurons: 109.2;Oligodendrocyte precursor cells: 33.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 138.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" 5.9 7.6 65.4 0.6 71.3 0.2 6.2 135.5 104.1 4.1 38.6 8.9 1.9 3.6 1.5 1.8 6.3 2.7 4.5 71.7 51.3 42.7 9.9 6.7 0.5 64.7 54.9 5.9 4.6 2.3 12.9 3.2 65.5 11.6 1.7 15.7 21.9 1.6 2.8 3.3 3.2 2.4 65.7 2.6 8.6 2.2 51.5 0.5 12.3 1.9 0.5 3.9 3.0 108.0 0.0 0.0 138.7 0.1 0.1 3.3 0.2 0.6 0.1 0.0 0.3 0.0 0.3 0.0 3.7 0.0 0.0 0.3 4.5 0.0 0.5 0.3 0.1 0.0 0.0 0.4 1.1 0.1 0.0 2.6 0.3 0.0 0.4 4.3 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 17.7 0.2 0.1 1.7 0.0 0.0 1.0 0.2 25.7 0.6 0.0 0.6 0.3 23.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 71.3 135.5 104.1 71.7 51.3 64.7 54.9 65.5 65.7 51.5 108.0 3.2 0.0 2.0 14.7 0.0 0.4 0.5 0.6 1.8 9.1 1.1 32.4 3.9 0.0 1.3 12.9 6.2 0.3 0.1 0.8 0.0 0.2 0.4 3.0 1.2 4.3 16.1 0.0 109.1 0.2 0.0 2.6 0.0 6.5 0.0 1.4 0.7 0.5 0.2 1.7 109.2 0.4 2.0 0.0 0.4 0.1 0.0 0.2 1.8 7.5 0.0 1.1 0.0 33.7 19.3 0.4 0.3 0.0 0.0 3.7 0.5 0.7 4.3 6.1 0.0 0.9 0.6 0.2 0.5 0.1 0.6 0.5 0.1 0.5 0.4 0.3 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 TMEM208 HSPC171 ENSG00000168701 "Transmembrane protein 208" Q9BTX3 16 67227103-67229278 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041868, HPA041949" Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA041868: AB_10962347, HPA041949: AB_10959903" "unprognostic (9.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.36e-3)" "unprognostic (2.05e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.44e-1)" "unprognostic (6.53e-2)" "unprognostic (6.40e-2)" "unprognostic (1.31e-2)" "unprognostic (2.29e-1)" "unprognostic (5.18e-2)" "unprognostic (7.73e-2)" "unprognostic (9.42e-2)" 35.5 83.8 41.8 31.7 41.9 22.5 40.3 44.0 50.1 34.7 50.3 42.9 45.8 29.2 57.5 41.0 32.7 27.8 26.6 41.8 44.8 52.9 124.7 34.9 28.0 43.8 44.6 25.2 65.3 67.6 62.6 32.7 43.9 34.1 41.7 13.8 44.9 31.1 26.5 32.9 39.1 28.1 43.4 38.2 47.4 30.4 43.8 26.5 41.3 19.0 32.1 36.9 28.7 44.9 64.6 82.1 40.0 48.6 124.3 59.3 73.4 66.3 83.3 72.1 61.4 106.4 80.1 63.4 76.1 93.8 64.6 86.2 64.4 89.8 45.6 27.9 90.1 34.9 64.0 110.1 128.6 56.2 91.6 79.9 112.7 95.1 82.1 51.5 54.3 57.6 61.2 81.4 85.7 128.0 56.2 82.5 67.2 105.5 56.1 61.0 48.7 186.2 97.4 42.9 66.2 67.6 119.1 50.2 54.8 27.2 65.0 70.7 33.8 54.5 35.9 78.3 74.0 122.7 127.9 131.8 96.0 54.1 79.8 79.2 108.5 59.4 74.0 102.7 66.5 70.7 68.7 63.9 85.1 58.5 56.1 61.6 69.7 53.3 81.3 168.5 74.2 93.9 41.8 41.9 44.0 50.1 41.8 44.8 43.8 44.6 43.9 43.4 43.8 44.9 51.7 25.6 36.9 8.1 71.8 51.7 79.5 131.0 48.9 44.7 92.1 96.9 29.8 102.9 111.1 57.0 33.3 98.9 69.2 81.8 60.7 158.8 19.8 57.6 54.3 49.5 76.8 31.6 7.8 202.0 142.9 66.7 50.0 64.1 53.3 47.1 43.5 209.6 120.5 26.9 9.3 119.0 140.4 54.7 53.6 7.4 62.1 59.4 88.9 6.5 90.2 102.6 55.6 9.0 12.3 129.7 107.8 41.8 197.3 137.6 145.4 162.7 109.7 55.5 26.3 43.6 100.6 68.4 58.4 62.7 51.9 143.7 52.4 65.9 95.4 128.0 TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.7;ovary: 19.6" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 32.6;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cell line enhanced" "Detected in some" "Karpas-707: 25.3;NTERA-2: 9.5;RPMI-8226: 17.1;SK-MEL-30: 27.7;U-2 OS: 11.8;U-87 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" 4.7 3.3 7.4 1.8 5.8 0.7 3.2 4.8 9.2 11.9 1.7 2.6 0.7 1.9 1.6 2.8 3.8 1.1 1.3 3.8 27.4 1.4 0.6 3.0 3.6 22.7 48.7 19.6 0.4 1.4 3.8 0.2 33.0 1.4 2.3 1.5 1.2 1.8 1.4 2.6 2.3 0.9 19.9 1.7 1.8 0.2 36.8 8.1 0.4 2.7 3.8 1.9 8.5 11.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.2 0.0 0.1 0.3 0.0 2.9 0.0 1.9 0.7 0.7 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 25.3 0.4 0.0 0.0 0.1 9.5 0.0 0.0 0.1 0.0 17.1 0.0 0.0 5.1 0.1 0.5 0.0 27.7 0.3 0.0 0.3 0.0 0.0 11.8 0.0 5.1 0.0 5.2 3.7 29.7 0.0 0.0 0.0 0.3 0.0 2.8 0.1 1.4 0.2 0.2 1.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 7.4 5.8 4.8 9.2 3.8 27.4 22.7 48.7 33.0 19.9 36.8 11.5 0.1 3.2 0.0 1.6 0.0 0.4 0.1 0.1 0.6 1.9 0.2 1.3 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.2 0.0 0.0 4.4 0.0 0.4 0.0 0.3 0.4 0.0 1.3 0.0 4.3 0.0 0.0 1.0 0.7 1.6 0.6 1.6 5.4 1.9 3.7 0.3 0.0 32.6 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 14.6 0.6 0.1 0.1 0.0 1.3 0.1 0.4 0.0 0.0 0.0 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM51 "C1orf72, FLJ10199" ENSG00000171729 "Transmembrane protein 51" Q9NW97 1 15152532-15220478 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 87.0;Exocrine glandular cells: 74.1;Pancreatic endocrine cells: 71.0;Urothelial cells: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014547, HPA019441" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA014547: AB_1858121, HPA019441: AB_2670142" "unprognostic (1.21e-1)" "unprognostic (1.84e-1)" "unprognostic (8.74e-2)" "unprognostic (1.89e-2)" "unprognostic (3.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.47e-2)" "unprognostic (7.81e-3)" "unprognostic (7.84e-2)" "unprognostic (1.39e-1)" "unprognostic (3.00e-2)" "unprognostic (8.91e-2)" "prognostic favorable (8.16e-8)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (5.58e-2)" "unprognostic (1.67e-3)" 5.0 20.5 8.1 8.8 8.1 0.8 5.5 18.1 10.6 16.0 7.4 19.8 22.8 5.3 7.3 17.6 11.3 21.2 5.8 8.0 7.4 36.0 4.0 14.2 4.8 9.4 8.6 21.3 45.1 12.9 7.0 10.8 8.5 15.7 10.7 0.4 10.4 15.3 1.7 8.4 20.1 7.9 8.2 7.0 30.2 2.6 8.8 2.2 4.8 3.0 5.0 30.3 18.1 9.1 42.7 22.4 12.5 3.0 2.1 4.5 0.0 4.8 20.1 14.5 19.6 29.6 46.8 0.0 15.4 3.2 20.7 40.2 4.3 15.7 8.2 0.1 11.1 1.0 1.2 29.8 17.8 0.0 39.7 1.4 13.7 18.9 20.6 9.3 13.6 1.7 6.5 0.1 7.5 14.7 0.0 0.1 2.3 33.7 8.4 5.9 8.0 7.4 37.0 43.3 1.9 37.0 4.0 16.2 40.6 7.5 2.3 4.5 9.5 15.0 13.2 6.6 15.2 0.4 0.6 0.1 14.8 0.6 18.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 8.1 8.1 18.1 10.6 8.0 7.4 9.4 8.6 8.5 8.2 8.8 9.1 2.7 0.0 2.6 19.9 1.5 18.2 53.8 9.4 15.4 0.1 9.7 6.7 3.0 34.3 10.7 49.7 0.0 6.3 0.1 20.3 5.9 87.0 0.5 10.0 1.9 10.5 19.2 0.0 0.7 74.1 0.9 10.3 26.0 15.7 0.0 0.3 8.6 0.4 48.1 0.0 8.1 18.7 57.0 31.4 19.2 0.4 2.8 22.1 14.2 23.4 13.1 0.0 0.0 11.6 0.4 71.0 27.2 13.9 0.3 53.7 14.3 12.1 11.7 0.1 32.9 1.6 30.3 0.5 3.6 20.7 21.2 1.4 1.1 1.0 15.4 117.9 TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" 10.5 12.2 6.8 14.7 6.6 7.9 20.1 6.1 8.0 12.9 6.9 28.4 28.6 11.0 18.5 10.5 8.4 12.1 5.0 5.9 7.1 7.9 7.4 11.7 15.4 7.5 10.0 6.0 11.3 12.9 9.2 15.1 8.0 30.7 27.8 6.9 15.4 15.9 3.1 13.7 30.5 13.4 7.1 15.5 22.8 5.0 8.3 9.7 15.0 4.2 14.6 17.1 9.0 6.9 21.7 6.4 5.9 25.8 24.9 32.6 21.4 35.5 46.8 21.9 26.7 16.6 28.6 20.9 18.2 47.3 30.2 34.9 3.8 21.6 28.7 12.8 4.1 27.5 4.6 15.2 24.7 19.6 28.9 22.3 25.9 28.0 22.0 21.4 23.6 9.6 16.9 13.1 31.8 13.7 9.3 10.8 4.8 35.0 16.4 7.6 8.9 17.0 20.3 30.2 4.6 6.4 15.4 38.6 34.6 15.5 20.4 14.7 26.6 22.3 6.8 17.6 7.8 10.6 18.1 12.9 25.9 10.1 16.3 5.4 3.0 2.6 3.2 5.2 5.6 5.9 6.9 4.4 2.7 4.9 6.2 3.6 1.8 3.5 6.7 2.7 7.4 3.6 6.8 6.6 6.1 8.0 5.9 7.1 7.5 10.0 8.0 7.1 8.3 6.9 18.3 28.9 13.9 18.9 23.3 12.2 14.5 20.9 39.9 5.0 32.9 14.4 4.6 20.0 21.6 18.4 2.1 15.9 12.3 59.5 0.0 42.9 18.7 14.4 26.5 19.9 17.4 6.3 18.4 89.3 25.5 17.5 46.4 24.9 13.3 14.5 35.7 10.1 21.7 6.7 16.4 53.6 12.2 37.7 10.9 24.5 9.9 22.7 3.6 30.0 20.9 4.0 6.2 21.6 23.1 69.7 47.1 3.0 21.6 28.9 44.9 4.7 17.9 7.9 0.0 5.4 17.2 4.9 5.6 29.9 12.8 29.1 20.5 11.8 38.2 23.9 TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "CACO-2: 277.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" 56.3 50.6 48.9 17.3 84.1 4.7 44.5 75.3 64.1 68.6 161.9 90.0 102.5 100.4 74.2 27.9 96.5 93.9 44.3 51.2 56.9 36.5 27.5 58.1 5.7 72.8 77.4 191.9 88.5 53.7 23.9 28.2 69.7 80.7 96.3 15.7 50.1 23.9 5.3 24.6 118.4 62.3 51.9 19.6 101.6 20.7 75.0 4.4 47.7 14.6 7.7 50.7 42.6 109.3 7.4 27.2 115.5 0.2 154.7 138.0 1.1 114.2 153.2 59.2 126.5 277.6 8.1 1.6 1.7 144.0 2.1 0.9 74.2 30.1 34.5 24.7 92.0 4.6 0.1 124.5 71.5 0.3 1.7 116.3 29.7 74.7 12.1 31.6 154.8 40.7 78.1 0.3 162.9 0.2 0.1 0.7 77.0 83.1 42.0 0.2 108.4 0.5 13.6 49.0 9.8 158.3 2.7 0.0 89.8 72.6 36.5 0.2 128.2 83.8 78.1 1.0 0.2 9.2 3.8 0.1 42.9 0.1 46.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.1 0.0 0.1 48.9 84.1 75.3 64.1 51.2 56.9 72.8 77.4 69.7 51.9 75.0 109.3 7.6 41.7 24.8 6.2 0.6 25.1 76.1 111.5 27.3 1.4 32.4 104.5 14.1 72.9 61.0 46.0 0.0 8.1 0.7 109.2 5.9 81.0 18.2 14.7 48.5 7.8 97.9 2.7 0.6 66.4 7.3 127.2 40.8 12.1 3.8 87.8 29.6 13.0 5.7 0.0 0.3 145.7 40.7 0.6 15.9 14.9 120.5 2.0 44.4 1.9 0.0 106.3 0.0 3.0 173.0 88.2 97.9 151.6 0.2 68.1 250.9 37.2 54.6 4.8 65.7 22.1 55.5 40.7 27.7 17.1 12.6 7.1 2.4 132.6 166.6 68.6 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" 12.2 7.4 4.8 13.6 4.9 9.7 9.4 4.2 5.3 11.4 6.7 15.4 15.5 9.9 10.3 43.4 13.2 11.8 6.9 4.2 3.7 13.5 13.7 21.7 12.8 5.0 5.2 6.9 8.0 7.3 3.4 21.9 4.9 7.5 15.4 3.6 12.8 9.8 3.4 15.0 16.0 9.6 4.9 13.7 16.9 3.4 5.8 12.6 9.6 6.4 19.5 16.4 18.7 5.0 59.4 56.0 22.3 5.8 21.6 35.9 25.8 26.1 35.5 26.7 23.8 21.8 42.4 13.9 21.7 28.0 18.9 82.3 20.7 58.5 33.9 23.8 9.1 20.6 62.6 17.9 24.0 26.6 22.1 24.2 55.7 21.5 66.2 32.9 47.7 20.0 22.3 20.6 32.6 43.9 17.8 17.7 12.4 36.3 10.3 21.0 26.7 37.8 43.5 41.5 5.4 14.6 43.5 28.9 15.6 29.7 19.7 21.0 53.8 33.9 22.6 27.8 31.3 12.5 39.5 15.6 21.7 48.0 20.4 47.6 27.9 41.4 22.7 34.7 20.2 20.4 19.8 20.3 20.6 23.8 16.7 15.7 45.5 18.8 39.3 29.0 26.0 16.7 4.8 4.9 4.2 5.3 4.2 3.7 5.0 5.2 4.9 4.9 5.8 5.0 147.9 397.4 68.2 23.8 43.5 106.9 91.4 66.3 70.6 8.3 38.8 27.3 45.8 30.0 112.7 42.3 14.6 56.1 63.3 117.4 41.1 85.8 38.9 67.5 87.6 131.6 18.6 50.9 29.4 71.6 66.3 84.1 71.9 91.3 143.0 28.8 101.4 52.9 53.9 15.2 25.5 52.0 36.7 51.7 74.1 99.3 45.1 88.4 32.0 33.7 67.5 19.2 60.8 17.1 17.1 152.6 79.0 44.4 44.1 160.3 65.5 56.5 82.2 12.6 13.1 35.2 58.0 14.5 13.9 137.0 132.1 51.3 74.3 57.4 59.9 215.9 TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 60.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 2152.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;WM-115: 80.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Actin filaments" "HPA026954: AB_2256025, HPA026955: AB_10602282" "unprognostic (1.56e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" "unprognostic (7.38e-2)" "unprognostic (2.60e-2)" "unprognostic (3.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.16e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-2)" "prognostic favorable (2.84e-5)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.06e-2)" "unprognostic (8.06e-2)" 3.7 0.8 11.4 4.7 39.8 2.1 4.6 21.4 25.1 4.8 0.0 11.7 2.8 5.4 4.4 9.8 10.0 7.8 2.0 11.2 19.1 6.6 1.2 6.4 1.8 28.3 29.9 1.9 4.5 2.8 3.5 3.4 26.7 6.1 5.7 5.5 6.9 11.2 1.2 5.2 4.7 6.8 11.7 1.3 10.2 3.0 26.8 1.5 6.4 1.7 2.2 7.5 7.3 60.8 1.7 6.4 32.0 0.2 4.3 3.9 2.9 2.1 0.7 1.7 0.3 0.3 3.4 0.0 0.5 11.9 1.2 2.8 9.7 4.9 0.5 7.5 5.8 0.0 5.2 0.2 0.4 2.2 1.0 1.1 4.3 0.2 1.6 3.4 2.7 3.5 0.0 4.2 0.4 3.4 1.6 8.8 1.1 6.0 5.3 0.0 1.3 0.6 2.9 14.1 8.3 15.1 2.9 4.6 21.0 5.4 4.9 0.5 1.7 5.3 1.8 7.2 2.7 7.8 5.7 1.2 1.2 3.8 80.2 0.0 0.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 11.4 39.8 21.4 25.1 11.2 19.1 28.3 29.9 26.7 11.7 26.8 60.8 10.7 9.6 8.9 333.3 2.0 14.4 15.5 12.0 18.2 38.1 8.9 5.5 1.8 11.5 18.4 14.7 8.4 13.6 3.1 3.6 0.0 5.4 12.9 13.5 7.5 10.3 2.4 0.8 117.1 8.2 1.7 9.8 12.8 13.1 0.0 0.2 2.5 1.4 1.9 8.4 377.0 9.8 2.0 6.6 9.6 5.0 5.9 6.2 32.0 86.2 9.3 13.9 1.0 38.7 2152.4 9.4 3.3 1.2 7.3 11.9 2.7 2.1 17.0 1.6 6.6 0.8 2.2 0.6 2.2 16.2 11.5 4.1 2.8 1.0 5.9 14.5 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNKS2 "ARTD6, PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798426-91865475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules NA NA "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Microtubules "HPA036606: AB_10673470" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (4.16e-1)" "unprognostic (1.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" 18.4 19.3 14.7 21.2 16.1 38.5 22.2 18.0 17.0 21.1 25.0 14.8 14.9 22.5 19.8 22.8 17.8 20.8 11.1 14.3 14.9 17.4 21.2 19.7 28.1 14.6 15.1 30.3 22.0 21.8 14.4 31.2 15.8 19.6 17.1 31.2 18.5 16.6 55.6 27.3 15.3 20.7 16.0 30.0 19.8 11.8 17.4 37.7 29.6 40.5 29.4 24.1 17.1 19.7 29.1 24.3 48.9 41.7 33.8 30.6 54.5 30.6 55.5 36.5 44.5 21.7 23.2 27.2 14.3 40.0 24.6 30.6 31.0 23.6 51.3 27.7 29.9 22.6 22.9 24.3 32.9 44.0 32.3 31.4 30.6 37.0 65.3 54.8 34.8 24.1 16.9 29.4 38.5 15.6 38.1 29.9 24.6 13.2 16.1 35.2 30.5 20.9 25.0 30.9 12.8 22.9 30.8 13.4 38.7 39.2 32.5 30.3 37.8 19.6 16.5 26.1 29.5 36.7 32.1 34.8 25.9 32.4 17.9 0.2 0.7 1.2 0.9 0.6 0.8 1.0 0.9 0.8 1.0 1.0 0.7 0.6 0.7 1.0 0.6 1.5 0.5 0.4 14.7 16.1 18.0 17.0 14.3 14.9 14.6 15.1 15.8 16.0 17.4 19.7 39.1 41.7 22.3 63.3 51.6 74.6 32.5 23.8 56.9 41.7 38.8 24.0 23.2 8.6 31.0 44.1 47.9 45.2 48.7 19.2 7.9 16.0 4.7 41.1 29.3 37.1 33.0 27.5 77.5 24.5 55.1 30.9 50.4 52.1 2.5 34.8 35.7 35.9 26.1 42.1 78.5 19.3 26.4 55.3 49.4 8.1 31.1 48.4 33.8 67.5 46.5 24.9 37.0 66.9 68.0 29.0 12.3 35.3 45.7 44.7 16.1 16.6 47.4 34.8 46.0 40.5 28.0 19.1 21.7 75.9 109.1 101.0 49.1 30.5 14.9 61.7 TNMD "BRICD4, ChM1L, myodulin, TEM, tendin" ENSG00000000005 Tenomodulin Q9H2S6 X 100584936-100599885 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 21.1;breast: 12.9;seminal vesicle: 26.1" "Cell type enriched" "Detected in some" 7 "Adipocytes: 73.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HAP1: 6.9;NTERA-2: 16.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034961, HPA055634" Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034961: AB_10670285, HPA055634: AB_2682868" "unprognostic (3.60e-2)" "unprognostic (9.84e-3)" "unprognostic (3.19e-2)" "unprognostic (7.77e-3)" "unprognostic (2.42e-1)" "unprognostic (2.15e-1)" "unprognostic (2.36e-2)" "unprognostic (1.37e-1)" "unprognostic (9.40e-2)" "unprognostic (9.60e-4)" "unprognostic (6.82e-2)" "unprognostic (5.67e-2)" "unprognostic (1.48e-1)" 21.1 0.2 0.2 0.6 0.1 0.0 12.9 0.0 0.2 0.5 1.1 0.8 0.1 0.3 0.2 0.3 0.3 0.5 1.0 0.2 0.5 0.8 0.0 0.0 0.1 0.5 0.5 2.1 0.1 0.0 0.0 2.4 0.3 1.3 0.5 0.0 0.5 26.1 3.3 3.2 0.5 0.7 0.1 0.2 0.1 0.1 0.4 0.4 0.2 5.8 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.5 0.5 0.5 0.3 0.1 0.4 0.1 73.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 3.9 0.0 0.0 0.0 0.1 5.3 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 3.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.7 0.5 9.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.7 3.2 0.0 0.1 0.0 1.0 0.0 0.3 0.7 0.6 0.0 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 25 "granulocytes: 8966.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 50 "basophil: 5.0" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Cell line enriched" "Detected in some" 7 "HMC-1: 297.5" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 16000000 "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 95.1 2.5 0.3 20.2 0.6 4.3 47.8 0.3 0.9 53.2 1.0 77.8 35.5 71.8 9.8 64.6 30.4 103.9 15.0 0.5 0.5 15.5 12.2 127.8 26.2 0.5 0.4 3.5 18.9 1.5 3.9 1.3 0.5 67.0 19.8 0.0 64.5 13.3 10.0 122.5 146.1 22.0 0.5 5.2 102.1 9.9 0.5 4.9 4.7 10.4 9.9 118.6 53.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.2 0.4 297.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 4.7 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.3 0.1 38.5 275.3 0.0 2.8 0.0 4.4 0.0 0.0 0.0 1.5 0.0 1.5 0.0 16.7 0.0 0.0 0.1 0.6 0.7 0.0 2.4 0.6 0.0 0.0 3.2 0.0 18.9 0.0 0.0 0.2 6.0 2.0 0.0 8966.1 0.0 0.0 0.0 3.8 0.0 0.1 0.7 0.0 0.0 0.0 1.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.8 5.4 0.7 0.1 3.6 0.0 0.0 0.4 1.1 0.0 0.7 0.0 0.0 0.1 345.1 0.0 1.0 6.1 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRADD Hs.89862 ENSG00000102871 "TNFRSF1A associated via death domain" Q15628 16 67154185-67159909 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 163.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004602, HPA071341" Enhanced Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB004602: AB_2209061, HPA071341: AB_2732178" "unprognostic (2.66e-1)" "unprognostic (3.11e-1)" "unprognostic (2.23e-2)" "prognostic favorable (1.40e-4)" "unprognostic (1.50e-2)" "unprognostic (1.21e-1)" "unprognostic (5.68e-2)" "unprognostic (4.96e-2)" "unprognostic (4.15e-2)" "unprognostic (2.24e-1)" "unprognostic (2.82e-1)" "unprognostic (8.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (1.83e-1)" 15.4 19.4 9.5 12.8 10.5 4.9 15.6 10.9 10.2 17.8 10.8 17.4 8.4 14.2 3.7 26.9 16.6 4.1 11.2 9.9 8.8 22.2 18.4 17.6 12.4 13.2 10.0 10.5 17.8 7.0 12.1 6.7 12.4 21.2 5.6 1.1 23.8 6.2 6.3 22.5 19.2 4.9 11.3 29.9 19.1 5.0 10.1 7.4 18.1 2.1 10.6 18.2 17.9 12.0 17.3 14.0 0.2 4.8 12.6 10.0 16.8 12.6 9.5 6.0 9.3 8.2 13.0 9.0 21.8 11.0 12.6 29.0 2.0 11.4 4.9 26.1 12.8 5.7 6.4 9.0 15.7 7.3 13.7 10.5 16.0 8.0 3.1 15.3 11.8 8.7 8.4 13.1 9.1 15.5 8.8 14.5 0.2 16.0 42.2 17.1 6.6 36.4 10.4 10.9 2.2 8.1 28.6 6.4 9.0 4.7 11.0 10.3 13.2 7.5 8.2 13.3 9.5 26.3 9.4 10.6 19.9 6.5 9.4 51.9 42.4 95.1 54.4 56.2 84.2 72.0 166.0 96.2 54.2 71.8 46.7 38.5 75.7 40.7 78.6 76.4 82.1 49.5 9.5 10.5 10.9 10.2 9.9 8.8 13.2 10.0 12.4 11.3 10.1 12.0 24.0 3.2 8.6 3.9 37.7 17.3 22.9 60.2 12.5 0.9 29.8 25.0 3.5 30.0 32.8 5.5 0.0 32.0 47.9 24.9 31.3 70.0 1.4 31.0 18.1 20.5 19.2 9.9 1.8 38.1 41.5 22.3 44.9 27.6 8.9 25.9 17.2 19.2 47.0 0.0 2.4 28.2 38.7 37.7 35.0 2.9 30.1 28.6 56.9 0.0 163.4 5.0 48.4 1.0 8.3 62.0 35.7 30.5 52.5 57.7 28.1 80.3 40.7 2.1 26.3 16.0 21.9 2.2 7.6 29.7 25.7 30.5 46.7 23.3 23.8 42.1 TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 168.9;skeletal muscle: 262.4;tongue: 202.6" "Cell type enhanced" "Detected in all" "Astrocytes: 173.0;Cardiomyocytes: 262.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" Nucleoplasm "HPA005853: AB_1854778, HPA011367: AB_2668495" "unprognostic (5.55e-2)" "unprognostic (1.38e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.56e-3)" "prognostic favorable (4.84e-8)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (1.00e-2)" "unprognostic (4.61e-3)" 26.0 13.1 23.0 17.1 26.2 18.2 18.0 28.5 27.7 13.7 27.8 27.1 34.5 12.2 10.4 29.3 19.8 26.9 168.9 24.2 19.5 20.1 15.3 24.1 22.8 24.4 30.3 8.5 13.1 32.2 17.7 15.3 21.6 15.4 25.4 96.7 44.1 13.1 262.4 45.1 42.0 16.8 19.1 22.2 61.0 12.1 26.0 17.9 31.4 202.6 22.6 33.8 18.4 21.4 22.2 19.2 37.9 16.4 25.6 24.9 48.9 29.5 33.5 19.0 20.6 12.8 30.7 43.9 15.1 75.2 20.4 10.7 26.5 68.8 20.6 39.6 18.8 30.4 19.9 35.6 12.8 34.6 22.9 21.4 28.9 41.9 38.0 28.1 38.6 11.6 15.7 34.4 24.4 9.2 3.7 18.1 16.4 60.4 14.8 16.1 14.1 36.8 26.3 165.3 23.8 27.9 11.3 16.3 16.2 31.4 14.6 29.3 39.6 16.6 19.2 99.0 17.4 25.7 23.0 38.9 18.2 30.2 16.4 0.9 1.3 0.5 0.6 2.4 0.5 2.4 0.9 0.7 1.5 3.6 0.3 0.9 0.6 1.0 1.4 2.5 0.4 0.7 23.0 26.2 28.5 27.7 24.2 19.5 24.4 30.3 21.6 19.1 26.0 21.4 27.4 32.1 32.4 173.0 23.9 38.0 16.3 32.1 30.1 22.7 18.5 17.7 262.0 24.3 38.1 14.7 100.1 23.0 13.9 61.4 1.9 10.8 1.1 53.3 21.8 23.9 22.8 6.5 62.0 12.3 18.3 14.0 81.1 70.0 10.8 11.5 6.8 10.3 15.7 33.7 81.3 39.5 26.4 15.7 33.4 3.0 1.8 23.3 24.9 97.4 17.9 27.8 4.1 105.1 64.8 24.2 37.1 2.6 5.4 18.5 97.9 10.2 80.6 139.9 32.9 15.9 29.9 1.0 3.9 27.5 43.2 15.7 7.5 4.6 35.6 27.0 TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" 0.2 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.4 2.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 1.0 0.0 0.9 0.2 0.0 1.3 1.6 0.4 0.5 6.7 0.1 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 9.0 0.0 5.7 0.0 15.4 15.5 0.0 0.0 11.4 26.6 0.2 0.0 0.0 0.0 23.2 4.6 0.1 2.7 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV25-1 "TCRBV11S1A1T, TCRBV25S1, TRBV251" ENSG00000282499 "T cell receptor beta variable 25-1" A0A075B6N4 7 142670740-142671244 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 24.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;T-cells: 2.7" "Group enriched" "Detected in some" 9 "basal ganglia: 4.4;cerebral cortex: 2.3" "Group enriched" "Detected in many" 51 "MAIT T-cell: 8.3;memory CD4 T-cell: 8.7;memory CD8 T-cell: 13.3;naive CD4 T-cell: 12.4;naive CD8 T-cell: 12.1;T-reg: 25.8" "Lineage enriched" "Detected in single" 106 "T-cells: 25.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.1 0.8 0.2 1.7 4.4 0.5 0.0 0.0 2.3 0.0 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.3 3.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.8 0.1 0.0 1.0 0.2 0.7 0.2 24.8 0.1 0.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.0 8.7 13.3 0.2 0.0 12.4 12.1 0.2 0.0 0.0 0.0 25.8 2.9 0.2 4.4 0.0 2.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.9;Inhibitory neurons: 111.4;Microglial cells: 52.5;Oligodendrocyte precursor cells: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 144.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: AB_2672381, HPA051273: AB_2681416, HPA059943: AB_2684173" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (2.39e-1)" "unprognostic (3.28e-3)" "unprognostic (6.64e-2)" "unprognostic (3.92e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-4)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (8.60e-2)" "unprognostic (5.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.78e-2)" 3.4 5.7 1.3 5.8 2.2 13.9 2.6 1.1 3.8 7.7 0.0 3.7 3.2 6.0 2.9 8.8 5.1 3.9 1.8 0.8 0.6 2.9 1.0 2.9 7.7 0.3 0.7 7.1 1.6 3.9 3.5 2.6 0.0 5.4 3.4 2.0 2.3 3.6 1.1 6.4 4.7 3.9 0.2 7.2 4.2 6.0 1.6 10.3 2.0 1.2 5.0 7.0 8.0 0.8 13.7 9.4 10.3 13.2 4.7 10.4 14.5 10.2 16.2 11.4 9.4 0.1 7.1 12.7 2.2 15.5 15.6 16.2 13.2 12.6 9.1 144.3 1.0 13.7 8.0 0.0 3.2 25.4 42.1 4.3 17.3 10.2 4.1 10.3 0.0 8.5 0.1 4.1 5.0 3.0 6.6 42.9 11.3 10.1 9.6 11.8 0.8 4.7 6.7 16.7 8.3 4.4 6.1 0.2 1.0 5.6 5.9 34.1 4.5 6.5 7.5 10.7 2.9 1.7 9.5 13.7 4.4 22.7 0.1 1.1 0.6 4.6 1.5 0.2 1.4 0.2 1.1 1.3 0.7 0.0 0.9 1.0 2.0 1.5 0.1 0.6 1.2 0.7 1.3 2.2 1.1 3.8 0.8 0.6 0.3 0.7 0.0 0.2 1.6 0.8 2.7 3.2 1.3 37.9 3.6 8.3 2.9 3.2 6.2 9.9 4.1 2.5 1.9 1.5 5.9 5.5 0.0 3.4 20.9 8.4 0.0 1.8 2.7 3.3 16.2 5.4 3.0 0.4 96.9 1.0 0.9 11.8 11.2 1.7 12.0 14.7 6.4 0.3 2.6 8.4 111.4 2.1 4.1 4.7 10.4 3.2 14.0 8.0 3.6 52.5 7.9 4.2 12.3 80.4 3.8 1.2 2.5 22.2 7.2 1.6 1.0 0.2 8.5 0.5 26.3 4.4 7.9 10.0 7.4 23.5 7.4 1.2 18.0 4.2 3.8 4.3 TRPC4 "HTRP4, TRP4" ENSG00000133107 "Transient receptor potential cation channel subfamily C member 4" Q9UBN4 13 37632063-37869802 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 11.9;seminal vesicle: 9.0;smooth muscle: 12.6" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 133.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;BJ: 20.2;BJ hTERT+ SV40 Large T+: 9.1;fHDF/TERT166: 19.6;U-2197: 9.3" "Region enhanced" "Detected in many" "basal ganglia: 43.1" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.52e-4)" "unprognostic (9.99e-2)" "unprognostic (5.42e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (3.28e-1)" "unprognostic (1.60e-1)" "unprognostic (5.10e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-6)" "unprognostic (3.73e-3)" "unprognostic (1.93e-2)" "unprognostic (3.24e-1)" "unprognostic (1.43e-2)" 0.8 0.4 2.9 0.8 7.1 0.0 0.3 0.0 3.5 2.5 0.0 3.1 0.4 11.9 0.8 0.1 1.3 3.3 1.2 4.7 5.4 1.8 0.2 3.4 0.1 0.9 2.6 2.7 1.3 0.2 0.2 1.3 0.6 6.7 0.6 0.2 0.2 9.0 0.2 0.1 1.0 12.6 0.6 0.2 2.0 0.1 2.5 0.0 0.7 0.2 0.0 1.6 1.6 1.2 0.0 0.0 8.7 0.0 1.2 2.6 0.0 20.2 2.9 9.1 4.4 0.0 0.3 0.0 0.0 19.6 3.1 0.0 0.1 0.0 4.2 0.0 0.1 0.0 0.4 0.0 3.1 0.0 0.0 1.3 0.0 2.6 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.2 0.1 9.3 1.8 4.7 1.2 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 7.1 0.0 3.5 4.7 5.4 0.9 2.6 0.6 0.6 2.5 1.2 0.3 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.3 12.3 0.6 0.0 0.0 32.0 0.0 0.0 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 133.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 15.0 0.0 0.0 0.0 2.5 1.4 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.2 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.6;intestine: 16.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.9;Glandular and luminal cells: 36.5;Microglial cells: 39.4;Oligodendrocytes: 81.1;Proximal enterocytes: 23.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.1;neutrophil: 7.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 23.1" "Cell line enhanced" "Detected in some" "BEWO: 3.8;HeLa: 2.4;Karpas-707: 1.3;RT4: 3.8;U-266/70: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 0.6 0.0 2.1 0.6 3.5 2.6 0.6 3.0 2.4 0.3 0.2 13.2 7.0 0.3 0.2 0.3 0.2 0.3 0.2 1.6 2.8 1.9 0.1 0.3 0.3 4.2 3.4 0.0 0.1 1.4 0.5 0.3 4.1 0.5 16.6 0.4 0.3 0.1 0.1 0.7 7.9 0.5 2.7 0.5 0.2 1.4 3.1 0.4 0.2 0.1 0.3 0.4 0.3 6.6 0.0 0.8 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.1 2.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.1 0.0 1.4 0.0 0.1 0.0 0.1 0.1 23.1 0.1 2.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 7.5 0.5 0.2 0.3 0.0 0.1 2.1 3.5 3.0 2.4 1.6 2.8 4.2 3.4 4.1 2.7 3.1 6.6 3.3 0.0 1.7 1.0 0.3 0.1 1.9 0.3 2.2 0.3 0.2 0.4 0.9 0.0 1.3 3.7 0.0 0.2 0.2 128.9 0.0 0.0 4.0 11.3 3.4 3.2 3.6 0.0 1.3 0.0 0.1 0.3 0.0 36.5 0.0 0.1 3.3 0.1 0.0 0.0 0.5 3.0 0.0 0.3 0.6 0.9 0.0 0.4 0.0 39.4 0.0 0.3 0.0 0.5 81.1 0.0 13.8 0.4 0.1 1.3 23.3 0.0 0.8 2.7 0.0 0.7 0.4 1.6 2.4 0.5 1.0 0.1 0.5 0.2 7.5 0.8 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.7;Extravillous trophoblasts: 105.1;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 96.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 213.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 58.1" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" 25.4 12.9 11.0 7.1 12.1 0.6 25.0 96.6 13.5 29.6 9.7 18.0 7.9 32.3 11.5 15.4 23.2 35.2 128.8 6.9 12.6 45.8 54.8 35.8 5.4 12.3 13.0 35.3 13.1 28.1 8.6 58.7 14.5 27.6 6.2 14.8 18.0 24.4 16.8 27.9 12.3 23.6 8.6 20.6 13.4 5.1 17.1 19.1 18.4 12.4 7.1 18.4 22.3 7.6 1.5 12.7 20.1 16.1 19.2 15.5 48.3 26.7 82.3 20.1 26.1 30.6 11.6 0.8 23.9 14.6 19.7 3.1 9.5 9.6 11.8 5.0 9.3 36.3 8.5 20.6 42.2 0.2 3.0 17.7 7.4 40.4 16.9 50.4 55.7 1.1 1.0 1.1 17.6 16.7 0.0 0.8 25.5 7.8 7.4 9.9 213.0 3.1 61.7 7.4 36.8 22.6 18.8 36.6 16.4 45.9 13.7 0.2 27.2 8.5 28.8 14.8 25.7 0.2 0.6 0.3 20.3 0.5 10.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.2 11.0 12.1 96.6 13.5 6.9 12.6 12.3 13.0 14.5 8.6 17.1 7.6 60.1 0.0 4.1 10.4 0.8 19.2 13.3 22.4 13.1 68.7 19.8 9.0 50.1 11.5 6.5 12.9 2.1 53.1 0.2 1.7 5.9 21.1 3.0 2.3 24.9 43.1 6.0 5.3 16.8 9.1 105.1 22.2 2.0 5.7 0.0 13.0 41.0 36.7 6.2 33.7 45.5 2.3 2.0 3.2 3.5 4.1 17.4 7.1 12.4 30.9 0.8 4.0 0.0 9.0 2.0 9.9 0.6 17.3 1.4 13.8 2.4 22.4 2.5 4.7 19.7 1.4 20.9 1.3 3.4 9.7 11.9 80.7 1.5 6.4 2.5 10.5 TTC8 "BBS8, RP51" ENSG00000165533 "Tetratricopeptide repeat domain 8" Q8TAM2 14 88824153-88881078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 66.8;Theca cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.8" "Cell line enhanced" "Detected in all" "SH-SY5Y: 118.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.19e-2)" "unprognostic (1.08e-1)" "unprognostic (5.47e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.49e-1)" "unprognostic (7.10e-2)" "unprognostic (5.00e-3)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" "prognostic favorable (7.77e-4)" "unprognostic (3.54e-2)" "unprognostic (2.51e-1)" "prognostic favorable (4.89e-4)" "unprognostic (1.65e-2)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (3.80e-2)" 8.3 38.9 13.9 6.6 14.6 9.3 18.6 11.8 14.2 15.5 20.4 9.4 6.0 13.5 35.9 13.0 23.2 15.5 11.5 14.9 19.3 13.6 13.2 8.9 4.3 14.0 14.4 68.9 12.0 22.5 22.4 6.8 12.7 23.6 9.9 37.4 10.0 18.6 2.6 8.8 5.8 14.4 13.3 6.8 8.4 23.7 16.5 5.9 37.1 4.2 5.0 16.4 5.0 13.4 19.8 28.1 16.7 16.2 35.1 43.5 14.0 24.0 37.6 31.8 21.5 7.9 37.2 8.7 20.6 30.3 19.3 28.5 18.1 19.4 32.2 6.6 7.3 5.5 9.1 11.1 25.4 10.6 1.9 27.3 23.9 23.0 19.9 30.4 19.3 11.6 20.5 9.8 27.3 33.9 10.9 10.2 8.9 10.3 27.0 3.3 23.0 5.2 31.3 30.6 19.6 118.5 38.0 21.3 22.4 11.5 52.6 8.3 11.7 22.6 11.9 20.2 16.6 1.2 6.8 3.8 33.3 2.8 9.9 13.8 0.7 3.8 0.4 0.9 0.6 0.4 0.5 0.5 1.9 2.2 0.2 0.4 0.7 1.7 1.5 0.7 0.0 0.5 13.9 14.6 11.8 14.2 14.9 19.3 14.0 14.4 12.7 13.3 16.5 13.4 3.7 3.2 9.0 38.8 2.1 8.8 8.0 12.3 19.4 17.0 11.7 9.1 6.0 10.0 11.2 9.2 39.6 10.2 0.6 4.3 13.7 13.5 8.1 24.1 10.6 4.9 10.8 4.8 51.1 6.2 9.7 12.8 6.1 11.7 0.0 66.8 5.3 8.0 6.7 20.2 53.4 6.1 6.1 3.5 6.6 7.4 19.6 4.4 7.2 14.0 0.4 12.5 1.0 51.3 21.3 7.8 2.4 25.2 3.7 4.9 2.3 15.5 28.3 41.7 19.7 5.8 12.2 14.6 6.9 8.3 6.5 1.8 1.2 69.0 6.6 4.7 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 TUG1 "FLJ20618, LINC00080, NCRNA00080" ENSG00000253352 "Taurine up-regulated 1" 22 30969245-30979395 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.83e-1)" "unprognostic (7.04e-2)" "unprognostic (1.87e-1)" "unprognostic (9.18e-2)" "unprognostic (8.34e-3)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.68e-1)" "unprognostic (2.89e-2)" "unprognostic (9.60e-3)" "unprognostic (3.98e-2)" "unprognostic (7.55e-2)" "unprognostic (1.50e-3)" "unprognostic (2.49e-1)" "unprognostic (1.93e-1)" "unprognostic (6.53e-2)" "prognostic favorable (8.27e-4)" 6.9 6.5 7.0 8.0 7.2 5.2 8.1 7.1 7.1 10.9 8.2 7.8 8.1 12.4 8.1 6.4 8.3 7.8 5.7 6.6 6.9 8.0 5.2 7.4 7.2 8.5 7.4 11.4 5.6 11.1 12.9 7.2 11.9 7.9 11.8 8.3 9.5 3.2 7.3 8.2 9.3 7.1 9.8 8.2 9.5 7.4 11.8 10.9 4.1 7.1 6.5 8.3 18.9 6.9 22.5 17.3 12.1 15.5 14.1 21.8 10.9 14.2 16.2 12.6 9.2 23.5 14.4 16.6 15.4 17.7 17.7 9.2 18.9 18.2 12.1 17.5 15.4 8.9 10.3 18.4 8.8 15.5 15.4 13.0 13.1 15.1 14.4 13.7 18.9 12.6 13.3 13.0 10.2 13.7 7.8 15.2 11.0 21.9 14.7 9.1 9.3 21.1 28.6 27.1 17.1 9.6 14.4 18.0 19.7 12.2 22.1 18.6 18.5 11.4 11.4 15.8 21.2 12.2 8.3 11.8 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 7.2 7.1 7.1 6.6 6.9 8.5 7.4 7.2 7.1 7.4 8.3 0.0 0.0 0.0 91.7 16.8 34.2 36.2 30.2 35.9 56.6 0.0 0.0 0.0 40.0 19.2 0.0 56.3 38.7 6.7 44.2 0.0 0.0 57.8 0.0 0.0 26.3 64.8 25.4 32.8 0.0 26.1 21.7 34.7 0.0 8.9 0.0 60.0 23.3 23.1 53.8 41.2 59.1 24.4 36.8 22.4 44.7 56.8 25.8 16.0 60.0 29.4 46.6 21.6 38.7 67.5 0.0 29.3 62.4 16.8 45.2 33.1 0.0 21.9 52.1 26.3 55.2 16.3 42.6 18.0 51.2 44.0 36.9 12.7 0.0 47.2 44.9 TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.9;Extravillous trophoblasts: 321.8;Syncytiotrophoblasts: 783.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" 23.3 68.8 18.7 8.4 18.4 0.1 28.3 22.3 17.1 25.0 46.6 14.5 9.3 31.9 100.8 11.8 57.6 16.7 34.9 17.1 48.2 25.2 6.9 18.4 6.8 8.9 11.6 73.6 35.0 54.0 69.6 80.5 8.9 46.4 15.5 40.9 12.1 29.7 4.5 8.2 8.2 32.5 7.7 5.3 10.8 23.2 21.0 7.5 9.5 5.7 5.6 34.0 13.0 8.0 52.1 38.4 104.3 96.7 125.2 126.7 0.2 74.9 168.8 85.2 139.3 0.1 0.1 0.7 24.5 105.9 92.4 39.3 37.5 76.1 116.0 0.1 49.8 0.0 30.1 6.0 51.9 0.2 5.6 111.8 22.8 121.0 43.1 113.7 6.9 15.9 70.9 15.6 123.2 41.2 20.6 0.4 49.2 0.0 33.5 24.8 88.7 0.3 108.3 127.1 40.7 74.6 0.0 40.6 56.5 76.2 49.8 0.2 29.0 71.9 71.3 31.3 36.5 0.0 10.0 0.4 1.2 0.0 102.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.4 22.3 17.1 17.1 48.2 8.9 11.6 8.9 7.7 21.0 8.0 88.6 0.0 10.3 13.4 0.6 9.9 61.1 123.5 63.7 50.4 40.0 52.1 47.5 18.6 47.0 79.1 8.4 472.9 0.9 2.1 17.6 179.0 11.5 100.8 48.6 36.2 95.7 0.0 141.0 12.2 321.8 53.4 7.7 35.0 1.3 39.3 7.5 0.0 41.8 32.0 155.3 26.3 95.6 0.0 6.3 7.6 34.8 1.5 24.9 24.4 1.6 35.9 0.0 61.3 3.9 23.8 4.1 23.0 2.6 63.8 0.0 23.7 172.4 28.1 39.5 2.0 49.7 60.9 47.4 26.2 4.1 783.8 1.6 46.6 7.8 51.4 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 TXLNB "C6orf198, dJ522B19.2, DKFZp451A175, MDP77" ENSG00000164440 "Taxilin beta" Q8N3L3 6 139240061-139291998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 82.0;skeletal muscle: 300.0;tongue: 189.1" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 260.7;Late spermatids: 67.2" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Daudi: 5.0;HSkMC: 3.0;REH: 2.6;RPMI-8226: 3.8;U-698: 7.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030401, HPA030402, HPA030403" Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA030401: AB_2673459, HPA030402: AB_10602486, HPA030403: AB_2673461" "unprognostic (1.54e-1)" "unprognostic (7.01e-3)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (5.75e-3)" "unprognostic (2.94e-1)" "unprognostic (1.09e-2)" "unprognostic (6.00e-2)" "unprognostic (2.06e-1)" "unprognostic (8.10e-3)" "unprognostic (4.79e-1)" "unprognostic (5.15e-2)" "unprognostic (2.16e-4)" "unprognostic (2.19e-2)" "unprognostic (2.21e-1)" "unprognostic (2.65e-1)" "unprognostic (8.05e-4)" 1.1 1.5 0.7 2.5 0.5 0.2 2.2 0.4 0.8 0.9 0.3 1.3 0.6 2.8 0.6 4.4 1.8 2.2 82.0 1.2 1.5 0.1 0.3 1.2 3.1 1.1 1.1 11.4 0.2 2.8 1.2 0.6 1.8 3.0 0.9 0.3 2.4 0.3 300.0 0.6 1.5 2.2 2.0 2.2 0.9 3.8 0.8 7.7 0.3 189.1 3.5 1.1 0.6 1.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.3 0.2 3.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.2 0.2 0.5 0.6 0.1 0.0 0.3 2.6 1.1 3.8 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.9 0.0 0.0 0.0 0.1 0.8 1.4 7.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.8 0.1 0.3 0.0 0.8 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.1 0.7 0.5 0.4 0.8 1.2 1.5 1.1 1.1 1.8 2.0 0.8 1.9 2.0 0.0 0.0 4.9 5.9 0.5 0.3 0.6 0.0 0.1 2.0 0.5 260.7 0.0 1.6 1.8 0.0 0.1 0.7 0.0 0.0 0.0 38.5 4.3 0.3 4.9 0.0 2.7 8.7 0.0 0.0 11.4 0.5 0.4 0.0 0.2 0.7 0.4 1.7 0.0 17.4 0.0 0.0 6.6 6.0 67.2 0.6 4.1 5.4 12.2 0.6 6.5 2.1 2.5 4.0 0.0 0.0 2.2 7.4 0.1 0.0 0.0 17.8 0.1 0.0 25.8 2.2 3.8 1.2 0.3 0.4 0.0 2.0 5.9 0.0 0.1 UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 52.5;granulocytes: 83.0;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 56.7;HEL: 55.7;HMC-1: 103.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 370000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" 21.6 21.4 10.1 32.7 10.6 40.2 20.7 10.4 12.1 25.6 10.4 29.0 43.4 22.5 15.6 18.7 23.8 27.7 17.9 9.8 10.5 25.6 23.0 35.4 51.2 13.7 11.1 32.8 17.2 2.9 14.1 19.4 12.1 34.8 26.1 1.2 42.3 22.4 9.1 20.5 48.6 20.6 12.3 65.6 27.5 5.8 12.2 39.8 31.8 10.3 33.6 23.1 23.3 13.8 11.6 0.1 0.9 0.3 30.2 31.7 3.5 6.1 27.0 42.7 56.7 0.0 23.9 0.4 4.8 22.4 18.3 6.2 0.1 10.9 3.7 29.9 0.1 55.7 0.6 3.5 22.3 5.3 103.7 49.0 0.7 16.9 1.0 29.6 21.7 2.0 0.1 3.4 10.0 0.3 11.6 13.7 0.1 0.0 1.2 14.6 1.0 1.9 8.8 22.3 0.0 0.9 7.4 10.7 3.8 0.6 1.1 36.8 9.7 8.3 1.1 3.7 2.4 0.1 0.2 0.3 23.2 19.8 2.0 20.7 22.5 38.5 16.4 32.9 14.3 17.1 15.0 14.5 21.3 18.1 13.4 12.4 6.8 17.1 27.6 7.6 15.9 22.0 10.1 10.6 10.4 12.1 9.8 10.5 13.7 11.1 12.1 12.3 12.2 13.8 17.3 32.1 20.3 11.4 28.0 3.8 6.3 10.5 6.8 0.2 9.2 9.1 6.9 17.2 16.6 12.9 0.0 5.2 15.5 28.7 0.0 9.5 6.9 5.8 3.0 13.5 9.5 8.0 0.2 7.8 3.5 11.8 52.5 6.5 83.0 13.2 16.1 7.6 21.6 0.0 0.1 21.7 8.2 20.1 6.4 34.1 11.1 32.5 0.0 15.0 16.8 2.4 19.6 1.0 0.1 5.2 21.7 11.3 14.1 4.4 51.8 5.6 12.8 1.2 6.6 5.8 8.1 0.9 0.3 7.3 4.7 2.9 17.7 6.9 20.2 6.6 UNC119 "HRG4, POC7, POC7A" ENSG00000109103 "Unc-119 lipid binding chaperone" Q13432 17 28546708-28552631 "Disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 20 "retina: 1168.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 671.1;Cone photoreceptor cells: 856.9;Muller glia cells: 301.5;Rod photoreceptor cells: 2038.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041912 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041912: AB_10795267" "unprognostic (8.93e-2)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (4.95e-3)" "unprognostic (2.10e-1)" "unprognostic (1.44e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.76e-3)" "prognostic favorable (8.09e-5)" "unprognostic (2.65e-1)" "unprognostic (8.08e-3)" "unprognostic (5.51e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (9.82e-4)" "unprognostic (1.71e-3)" 17.7 29.3 48.1 23.6 47.8 55.9 20.7 44.0 59.2 25.9 54.7 19.9 12.0 21.3 17.8 25.3 19.1 14.3 24.5 49.7 49.5 36.6 32.9 21.1 29.7 49.3 45.9 21.3 24.5 22.2 28.8 11.0 49.7 29.8 10.9 1168.7 26.7 20.1 6.1 32.6 26.0 13.7 43.9 55.5 20.3 53.1 51.4 17.5 23.1 6.2 29.6 22.9 25.9 45.6 24.9 30.7 30.0 42.0 31.1 30.2 14.7 20.0 27.4 35.7 33.4 42.7 8.1 20.2 21.2 30.9 24.5 39.7 25.6 29.8 19.0 37.6 47.8 14.0 15.5 13.2 21.3 20.9 42.1 27.8 40.4 25.7 12.7 33.4 28.9 21.5 14.6 16.3 22.1 39.1 20.8 20.8 29.3 21.0 21.9 32.8 49.2 9.0 27.2 27.2 11.7 41.1 28.8 46.4 31.1 34.5 36.7 35.7 22.1 20.4 38.5 33.3 19.8 18.6 20.7 4.6 33.7 33.5 19.1 21.6 48.7 120.2 8.9 122.1 8.9 29.1 16.9 13.7 82.3 42.6 18.7 13.4 131.5 18.2 212.4 93.4 16.5 36.3 48.1 47.8 44.0 59.2 49.7 49.5 49.3 45.9 49.7 43.9 51.4 45.6 10.4 0.0 5.4 5.2 34.5 13.4 16.3 38.8 34.1 671.1 25.2 33.8 12.6 18.6 17.9 12.9 856.9 25.3 48.7 22.9 33.2 20.4 3.0 5.5 8.4 24.0 25.3 4.8 8.8 18.3 9.0 13.6 11.2 7.8 12.7 14.1 8.9 13.8 34.6 146.4 11.3 14.3 34.6 41.0 89.8 6.6 14.6 44.6 19.6 4.7 56.8 301.5 59.8 4.5 1.2 17.8 16.4 21.4 19.6 22.1 23.8 20.6 6.7 2038.5 46.0 6.6 15.8 1.5 16.6 20.6 14.3 20.0 25.3 14.1 13.7 18.9 UNC13C "DKFZp547H074, Munc13-3" ENSG00000137766 "Unc-13 homolog C" Q8NB66 15 53978201-54633414 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 103.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 73.1;Early spermatids: 184.4;Excitatory neurons: 130.3;Inhibitory neurons: 301.3;Late spermatids: 65.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Karpas-707: 73.7;U-266/70: 97.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 198.6" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.85e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (1.45e-1)" "unprognostic (6.90e-3)" "unprognostic (1.58e-2)" "unprognostic (9.69e-2)" "unprognostic (2.42e-2)" "unprognostic (1.26e-1)" 0.1 0.2 10.5 0.1 11.2 0.1 0.1 103.6 25.6 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.4 0.2 19.0 26.4 0.9 0.0 0.1 0.3 29.5 38.4 0.8 0.0 0.0 1.1 0.0 34.9 0.0 0.1 19.1 0.1 0.0 3.5 0.1 0.1 0.0 6.2 0.1 0.1 8.7 16.9 0.0 0.6 0.0 0.3 0.0 0.0 11.7 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 97.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.5 11.2 103.6 25.6 19.0 26.4 29.5 38.4 34.9 6.2 16.9 11.7 0.1 0.0 0.0 8.5 0.1 0.4 0.4 0.0 0.0 73.1 0.1 0.3 0.8 1.5 0.0 3.7 6.2 1.0 1.3 0.0 0.0 0.0 184.4 0.0 0.0 0.4 0.0 0.0 130.3 0.0 0.1 0.4 0.0 0.1 0.0 0.5 0.7 0.0 0.1 0.0 301.3 0.0 0.0 0.0 0.6 65.9 2.1 0.3 0.0 3.7 0.0 3.2 0.0 4.5 3.2 0.0 0.0 0.4 0.0 0.3 0.0 0.4 0.0 33.8 0.0 2.2 0.7 1.2 1.2 0.0 0.1 0.3 0.1 0.5 0.0 0.5 UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 76.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 96.2;Kupffer cells: 78.3;Macrophages: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "CAPAN-2: 128.9;RPMI-8226: 368.2;SK-BR-3: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA038716: AB_2676169, HPA038717: AB_10674836, HPA042803: AB_2678176" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (7.66e-2)" "unprognostic (1.29e-2)" "unprognostic (9.36e-2)" "unprognostic (5.82e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.76e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.73e-2)" "unprognostic (1.85e-2)" "unprognostic (7.05e-3)" "unprognostic (5.23e-3)" 18.7 17.7 4.9 19.9 5.6 19.9 15.4 5.0 7.5 19.0 6.4 20.2 22.5 7.7 0.8 20.5 15.7 9.8 7.3 4.9 5.0 16.4 15.3 29.5 29.5 10.7 6.5 6.2 17.1 2.6 6.7 6.4 8.1 16.4 3.1 0.1 27.9 8.8 3.5 16.3 35.8 3.1 7.9 76.7 20.6 1.7 6.8 3.5 14.8 1.5 7.3 20.6 15.0 10.2 18.9 34.1 2.5 13.8 7.2 2.7 28.2 8.3 7.7 13.0 11.8 2.8 128.9 40.9 30.8 4.0 11.0 44.9 1.0 7.0 0.4 14.1 9.3 4.2 11.1 6.4 11.2 30.0 22.7 6.0 7.6 3.8 1.5 5.0 2.6 6.4 3.0 19.3 2.0 18.7 0.2 23.9 6.2 46.8 16.7 24.5 0.0 368.2 11.8 10.7 3.9 5.5 14.0 95.6 19.3 1.0 35.4 39.0 9.2 8.6 12.2 12.8 0.8 13.2 18.8 7.0 16.0 30.7 10.5 0.1 3.8 6.6 0.1 7.2 0.2 2.5 0.2 0.2 5.1 2.7 0.0 0.0 3.2 2.1 7.7 14.8 0.0 1.2 4.9 5.6 5.0 7.5 4.9 5.0 10.7 6.5 8.1 7.9 6.8 10.2 12.5 9.6 9.1 4.6 45.3 4.0 21.9 12.5 9.1 0.0 16.4 13.1 1.8 40.0 21.0 16.5 0.0 10.3 63.3 23.2 1.9 36.8 0.8 32.0 5.9 10.0 4.2 3.0 1.1 23.4 47.8 8.0 20.9 17.2 7.0 9.3 10.0 5.4 96.2 5.0 0.1 17.2 14.2 78.3 28.4 0.1 4.4 85.3 23.2 13.1 57.5 4.7 8.2 0.0 0.7 49.7 25.6 4.1 33.8 27.0 31.7 6.9 57.3 0.5 0.0 8.3 9.8 0.2 1.1 12.9 6.5 7.3 10.5 2.1 23.1 37.7 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 51.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.7;Muller glia cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SuSa: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favorable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favorable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 1.4 3.1 2.5 0.9 2.7 0.5 1.7 2.8 2.8 1.9 4.2 0.8 0.4 3.1 51.7 0.6 5.5 0.8 2.1 2.2 4.2 3.7 1.2 1.5 1.1 2.2 3.1 6.5 1.1 5.6 1.4 2.4 2.4 2.4 0.8 3.1 0.8 2.5 0.4 1.1 0.7 1.9 2.5 1.8 0.8 2.3 3.8 2.4 5.3 1.1 1.2 0.9 0.7 2.5 0.0 0.6 3.9 1.1 1.9 1.0 0.0 0.6 0.3 0.7 0.9 1.2 0.5 0.0 4.6 0.8 0.8 0.2 1.0 0.4 1.2 1.3 0.0 1.0 0.2 0.0 0.8 2.5 0.2 3.9 0.0 0.4 0.0 0.3 0.2 3.0 3.1 3.0 0.6 2.6 2.4 1.3 4.8 0.0 0.2 3.4 0.7 1.5 0.9 0.1 0.0 0.7 1.1 0.1 3.7 7.0 0.9 1.3 0.2 1.5 2.1 0.4 0.1 4.7 2.0 0.9 1.0 1.4 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 2.7 2.8 2.8 2.2 4.2 2.2 3.1 2.4 2.5 3.8 2.5 5.1 3.2 5.5 3.3 2.6 0.9 2.2 0.9 2.2 23.7 3.8 7.4 6.9 1.5 2.0 3.7 6.2 4.3 1.2 0.2 9.8 1.5 0.3 9.0 9.2 6.0 3.6 5.0 2.7 0.0 2.2 8.1 0.0 2.1 1.3 7.9 6.4 0.7 7.6 6.7 5.0 0.5 0.0 5.6 2.5 1.0 4.1 4.7 5.4 1.9 0.3 32.9 3.1 3.5 3.7 0.2 0.3 8.2 1.0 1.0 0.0 13.1 11.2 16.4 0.0 7.1 5.0 11.4 12.5 1.0 0.4 2.7 3.1 13.0 0.4 0.5 UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285701-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 410.3;Early spermatids: 527.1;Late spermatids: 332.1;Microglial cells: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 219.4;HUVEC TERT2: 157.0;TIME: 203.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 52.6 17.4 26.8 25.8 40.5 56.6 40.5 32.7 18.3 40.4 35.6 33.8 17.0 29.8 16.8 27.9 43.5 31.2 24.8 18.4 67.9 30.9 25.3 49.3 34.9 48.6 52.1 37.2 52.1 69.4 7.9 45.8 49.7 39.7 31.7 11.0 26.0 26.1 14.0 27.5 22.3 25.9 40.0 71.5 27.2 59.2 48.8 43.2 68.4 38.9 35.8 25.2 16.0 31.0 27.2 22.6 39.3 51.0 66.5 60.5 23.4 39.0 37.8 31.1 45.2 86.1 9.8 8.4 33.6 88.4 36.6 15.6 219.4 32.9 44.6 90.6 25.5 32.2 24.9 51.6 26.3 36.1 0.7 35.5 6.8 46.2 24.1 29.3 157.0 25.1 2.0 22.7 44.1 18.1 28.7 15.5 15.9 16.6 23.9 25.7 70.2 0.8 35.9 0.7 49.7 0.9 60.8 8.4 23.5 59.5 33.3 48.2 203.6 29.8 37.0 15.5 37.6 17.7 25.3 1.3 18.2 21.5 49.5 41.2 40.9 23.2 39.5 120.8 28.3 25.7 24.9 33.0 17.2 35.7 21.8 22.8 34.5 37.6 173.9 50.4 22.2 13.9 26.8 40.5 32.7 18.3 18.4 67.9 48.6 52.1 49.7 40.0 48.8 31.0 267.0 410.3 138.7 148.2 101.2 29.4 31.7 17.2 40.9 6.5 47.4 32.1 56.0 28.6 111.0 31.3 0.0 94.4 175.1 10.9 0.0 25.3 527.1 61.2 51.5 171.8 31.2 19.8 61.2 32.0 6.9 51.6 76.5 87.5 29.7 22.8 83.6 15.6 22.3 60.6 161.4 16.9 8.2 109.7 45.9 332.1 23.9 97.6 39.2 425.3 79.8 29.1 171.0 68.9 4.1 28.1 9.3 33.4 70.3 25.4 3.6 7.1 87.3 4.3 144.7 151.0 157.8 6.6 6.6 33.7 45.5 129.3 108.0 32.0 22.3 19.2 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 67.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 139.7;Early spermatids: 72.8;Late spermatids: 95.3;Microglial cells: 53.4;Rod photoreceptor cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 46.1;HEL: 35.1;HUVEC TERT2: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA000653: AB_1080551" "unprognostic (1.47e-1)" "unprognostic (9.13e-2)" "unprognostic (2.56e-2)" "unprognostic (7.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (6.94e-2)" "prognostic favorable (6.56e-6)" "unprognostic (8.84e-2)" "unprognostic (6.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "unprognostic (1.73e-1)" 12.1 18.5 33.2 12.3 34.0 3.0 7.4 30.8 28.8 9.2 21.3 7.9 5.6 11.9 4.2 4.3 8.7 9.0 36.0 28.1 30.8 8.1 3.8 16.0 7.8 38.7 36.3 13.4 5.7 3.9 13.7 19.9 36.6 6.5 5.2 67.6 5.6 4.5 7.5 4.6 8.2 11.5 37.1 18.3 5.1 13.2 36.1 3.2 6.1 7.0 6.6 8.5 6.6 36.4 1.1 5.6 46.1 13.8 11.6 8.4 2.3 4.0 1.3 3.4 1.4 1.5 3.1 2.1 2.8 3.2 4.2 1.3 7.3 1.5 1.0 25.0 5.3 35.1 3.4 1.5 6.9 1.5 3.5 4.5 0.3 1.3 0.2 10.4 85.0 6.2 1.6 0.4 1.1 7.1 1.3 3.0 4.7 1.4 2.8 1.3 4.6 1.0 0.9 2.6 19.1 14.8 4.6 1.8 2.2 9.1 7.8 7.4 24.2 4.3 9.6 5.2 2.0 2.0 1.1 1.2 6.1 11.2 8.3 0.0 0.8 0.0 0.6 2.0 0.5 0.1 0.3 0.3 1.3 0.3 0.2 0.3 0.0 0.2 2.7 2.4 0.1 0.5 33.2 34.0 30.8 28.8 28.1 30.8 38.7 36.3 36.6 37.1 36.1 36.4 17.3 0.0 2.3 7.2 2.7 0.6 0.0 0.3 0.0 9.4 0.9 2.4 10.9 1.5 0.7 1.8 139.7 0.4 11.1 0.0 0.0 0.9 72.8 0.8 7.7 27.5 6.7 0.0 13.4 0.0 0.3 7.6 1.5 0.6 12.0 18.1 31.8 1.2 14.8 0.0 11.9 0.4 2.0 14.2 9.3 95.3 1.8 23.6 1.8 53.4 7.6 15.2 3.1 21.6 21.8 0.3 0.0 3.0 0.4 0.0 0.0 0.2 0.0 98.8 13.1 5.5 10.0 0.8 2.3 0.4 0.1 0.3 1.8 5.7 0.2 0.1 VASH2 FLJ12505 ENSG00000143494 "Vasohibin 2" Q86V25 1 212950520-212992037 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.9" "Group enriched" "Detected in many" 6 "Early spermatids: 92.8;Late spermatids: 80.8" "Cancer enhanced" "Detected in many" "testis cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 24.2;AN3-CA: 29.6;NTERA-2: 46.2;RH-30: 135.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045820 Approved Cytosol "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA045820: " "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.57e-2)" "unprognostic (1.25e-2)" "unprognostic (4.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.50e-2)" "unprognostic (2.45e-1)" "unprognostic (6.58e-2)" "unprognostic (1.84e-5)" "unprognostic (1.95e-3)" "unprognostic (2.74e-1)" "unprognostic (6.85e-2)" "unprognostic (6.81e-4)" 1.7 0.1 0.9 3.3 0.8 0.9 2.0 0.2 1.1 1.7 0.0 0.5 0.7 1.9 0.4 4.0 0.7 2.6 1.1 0.6 0.4 0.4 0.2 1.1 2.3 1.6 0.9 0.6 0.2 0.8 2.6 0.8 1.6 2.7 0.6 0.5 0.9 0.8 0.5 0.5 0.9 1.8 0.2 1.2 0.8 7.9 2.1 4.3 0.3 0.8 2.1 1.4 0.5 0.7 0.3 1.7 24.2 29.6 0.2 0.1 4.0 0.1 0.0 1.0 1.3 0.1 0.6 0.1 0.4 0.1 0.6 0.1 9.9 0.0 1.2 20.3 3.7 2.0 1.4 1.5 0.1 0.2 0.4 3.8 0.0 1.3 0.0 0.6 0.3 11.4 0.1 5.9 2.0 0.5 13.1 1.5 46.2 0.0 3.6 7.6 135.5 1.3 0.2 1.9 5.6 8.6 3.1 0.2 0.3 12.4 4.5 0.9 0.0 1.0 2.7 0.6 1.3 3.4 6.2 0.9 0.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.8 0.2 1.1 0.6 0.4 1.6 0.9 1.6 0.2 2.1 0.7 0.9 0.0 1.1 0.0 0.6 1.5 0.8 0.2 5.7 3.0 4.1 6.0 1.2 0.0 0.0 0.0 2.1 0.1 12.6 0.2 0.0 0.7 92.8 0.9 1.4 1.1 1.2 0.8 5.4 0.2 0.3 10.9 2.0 1.0 0.0 11.2 0.0 0.1 0.2 1.7 4.3 0.2 2.0 0.3 3.2 80.8 0.3 1.5 0.0 0.0 0.7 0.4 0.0 0.5 0.6 0.1 0.0 0.7 1.0 1.5 0.0 0.4 0.9 2.0 0.0 8.4 4.0 3.2 1.1 0.4 1.6 0.0 0.5 0.1 0.3 0.4 VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 385.2;skeletal muscle: 914.4;tongue: 942.7" "Cell type enhanced" "Detected in all" "Spermatocytes: 403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026864: AB_1858733" "unprognostic (2.55e-2)" "unprognostic (1.96e-2)" "unprognostic (9.88e-3)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-1)" "unprognostic (4.98e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.74e-1)" "unprognostic (1.19e-2)" "unprognostic (6.16e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (8.78e-3)" "unprognostic (6.94e-3)" 67.5 76.2 117.3 59.1 119.4 92.1 70.3 116.8 150.6 53.7 115.4 106.9 79.8 63.5 68.6 99.9 85.8 56.0 385.2 121.1 130.8 108.8 92.9 51.9 66.3 122.7 119.3 61.6 64.6 92.4 58.9 63.9 139.2 69.5 106.4 123.1 61.6 81.3 914.4 54.1 73.0 92.8 114.1 67.3 72.1 114.5 118.6 80.1 83.3 942.7 79.3 78.9 59.8 113.8 226.3 225.7 174.5 185.9 146.3 126.6 84.8 180.0 151.1 225.4 205.2 173.4 190.4 235.8 165.0 153.7 196.3 142.5 238.4 194.1 244.7 117.2 196.6 352.9 138.4 250.2 105.2 172.0 190.1 98.6 143.3 171.6 80.9 149.6 279.8 201.3 284.4 158.6 235.7 126.4 373.3 197.1 205.2 285.6 144.5 193.6 322.1 165.3 245.7 198.8 156.8 133.3 112.1 132.8 116.1 126.4 279.9 129.9 149.8 86.6 150.0 217.7 174.0 145.2 264.1 266.9 117.5 238.0 150.9 142.8 165.3 183.4 145.8 167.2 148.7 126.5 155.6 146.5 222.7 96.6 152.7 147.7 82.8 125.8 155.6 163.0 202.5 360.5 117.3 119.4 116.8 150.6 121.1 130.8 122.7 119.3 139.2 114.1 118.6 113.8 78.1 44.8 24.4 50.6 59.8 64.5 81.1 197.8 58.1 85.9 53.0 73.9 321.2 55.8 82.8 66.2 35.5 145.5 91.9 65.7 307.2 116.3 151.1 112.8 56.7 70.5 47.8 186.4 63.2 90.0 112.1 81.5 41.3 47.1 55.2 100.6 68.2 60.4 139.7 138.0 78.9 86.1 177.0 58.5 77.8 146.4 69.3 107.7 72.9 26.2 130.1 72.9 83.4 38.2 34.7 84.9 86.7 97.4 75.9 48.9 125.3 177.5 142.1 94.5 65.7 146.4 123.8 403.7 156.3 82.3 70.8 58.3 79.7 94.2 124.8 70.4 VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 20.6;Excitatory neurons: 15.2;Muller glia cells: 38.9;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 45.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cell line enhanced" "Detected in some" "HeLa: 6.6;HMC-1: 9.0;MOLT-4: 12.9;U-266/70: 40.5" "Region enhanced" "Detected in many" "olfactory bulb: 27.1" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" 12.5 0.8 2.2 0.9 1.6 0.4 2.5 0.6 6.9 16.8 1.4 13.8 1.7 6.8 12.2 1.4 4.5 2.5 16.4 2.1 2.0 1.1 0.4 0.6 1.1 2.2 0.8 12.0 17.5 0.9 2.7 5.7 2.6 9.2 1.1 6.5 0.3 20.5 7.4 0.7 4.8 4.2 2.1 0.8 8.6 2.2 1.3 8.2 0.2 5.4 0.4 6.8 11.2 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.2 12.9 0.1 1.0 0.0 0.0 3.2 0.1 0.7 0.0 0.0 2.8 2.3 0.1 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.0 0.0 40.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 12.3 0.0 0.1 2.2 1.6 0.6 6.9 2.1 2.0 2.2 0.8 2.6 2.1 1.3 2.9 0.8 0.0 0.0 2.9 0.7 0.6 2.9 0.0 1.8 1.7 1.6 1.8 7.5 0.0 0.0 0.0 2.1 0.0 20.6 0.0 0.0 0.0 1.3 0.4 6.9 0.4 0.0 0.0 15.2 6.7 0.0 10.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.3 1.9 10.2 0.5 1.8 1.9 0.0 38.9 4.1 49.8 0.3 0.8 0.0 2.6 2.4 2.0 0.0 0.5 0.0 45.1 0.0 2.9 5.6 3.6 10.2 0.1 0.0 0.0 3.8 0.1 0.0 0.3 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 VPS54 "HCC8, PPP1R164" ENSG00000143952 "VPS54 subunit of GARP complex" Q9P1Q0 2 63892146-64019428 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 81.8;Microglial cells: 76.8;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055894, HPA067981, HPA070582" Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Nucleoplasm "HPA055894: AB_2682961, HPA067981: AB_2685938, HPA070582: AB_2686282" "unprognostic (1.35e-1)" "unprognostic (3.37e-2)" "unprognostic (6.47e-2)" "unprognostic (2.46e-1)" "unprognostic (3.37e-1)" "unprognostic (9.47e-3)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.16e-1)" "unprognostic (4.62e-2)" "unprognostic (1.82e-1)" "prognostic favorable (2.03e-4)" "unprognostic (3.20e-1)" "unprognostic (8.38e-2)" "unprognostic (3.02e-2)" "unprognostic (1.36e-1)" "unprognostic (1.57e-1)" "unprognostic (4.91e-2)" 11.7 11.5 8.1 10.6 9.7 15.0 14.5 13.5 9.6 13.5 10.9 11.6 13.0 14.4 12.3 10.8 12.4 10.4 8.4 7.8 8.5 16.0 14.4 13.1 11.1 8.8 8.7 14.6 17.0 28.3 13.0 13.5 8.9 17.4 13.4 17.3 36.8 12.8 9.3 10.9 12.2 12.8 8.5 12.9 14.4 13.4 8.5 13.2 17.7 9.9 11.2 10.9 9.8 11.0 23.3 11.9 22.5 17.4 15.7 17.1 16.6 14.3 21.4 15.0 14.9 22.0 14.9 15.8 10.5 20.1 22.3 10.7 22.1 12.9 27.1 23.0 15.9 14.7 10.0 38.9 15.0 10.3 6.2 16.3 19.8 10.5 22.7 18.0 23.0 11.3 16.6 13.4 19.4 10.1 10.9 11.5 13.8 22.9 9.1 10.8 21.8 9.0 17.1 13.1 13.1 19.6 12.8 16.3 17.8 17.3 11.9 20.6 16.8 19.3 15.3 11.8 23.9 30.8 8.7 20.4 14.3 20.5 16.4 1.0 0.7 0.3 0.5 0.6 0.5 0.6 0.4 0.5 0.4 0.7 0.6 0.5 0.6 0.7 0.5 0.6 0.9 0.2 8.1 9.7 13.5 9.6 7.8 8.5 8.8 8.7 8.9 8.5 8.5 11.0 16.6 16.0 22.3 62.7 5.2 11.1 8.7 6.4 3.4 20.9 11.8 9.8 14.3 15.7 14.2 1.8 12.5 6.5 6.4 11.1 1.9 6.8 53.9 9.3 16.6 13.4 13.2 2.1 71.6 13.2 6.8 11.8 15.8 11.0 2.5 15.2 10.8 15.4 8.1 23.5 81.8 17.4 2.0 9.8 9.3 37.4 18.6 12.2 5.4 76.8 9.6 9.4 3.1 105.6 108.9 11.3 12.8 12.4 7.7 17.3 11.6 9.9 10.6 16.2 19.7 13.4 12.8 14.9 8.3 9.4 10.4 5.5 7.5 15.9 12.9 13.8 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Gastric mucus-secreting cells: 33.1;Plasma cells: 57.2;Squamous epithelial cells: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057067 Approved Approved Cytosol No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Cytosol "HPA057067: AB_2683326" "unprognostic (5.94e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (6.05e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (5.80e-2)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "prognostic favorable (6.83e-4)" "unprognostic (1.17e-2)" "unprognostic (1.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (6.36e-4)" 36.9 70.7 141.7 19.6 145.8 31.9 37.7 139.4 171.9 48.2 133.1 46.6 29.1 39.1 44.8 35.7 56.1 36.5 49.9 137.7 136.6 71.2 80.3 33.7 32.2 144.2 141.3 55.6 62.3 73.7 60.8 24.9 138.2 69.9 17.7 24.4 56.4 37.3 31.4 34.9 33.2 19.8 138.1 42.5 58.0 31.8 145.0 44.7 66.9 53.9 20.6 45.7 37.5 139.0 20.6 91.3 56.2 66.7 69.9 54.0 45.7 20.6 40.3 22.4 17.5 47.3 41.9 19.4 39.3 48.9 33.2 28.3 24.8 55.8 19.0 74.3 49.1 27.4 41.4 68.9 47.6 10.3 27.4 76.2 58.9 30.4 42.2 93.8 44.7 51.6 11.5 72.0 54.8 133.8 40.1 25.5 43.3 53.6 46.3 36.4 63.5 33.6 55.9 83.1 35.0 81.3 28.2 49.9 62.5 49.4 65.5 26.9 26.5 53.0 41.9 20.0 23.5 106.7 38.8 22.2 56.2 27.0 48.5 24.1 28.5 19.2 26.5 23.5 22.5 28.4 23.0 25.5 30.2 27.8 31.3 28.0 18.6 34.6 20.1 47.0 39.2 27.1 141.7 145.8 139.4 171.9 137.7 136.6 144.2 141.3 138.2 138.1 145.0 139.0 1.5 3.2 4.2 0.0 14.3 0.9 0.6 2.0 29.0 1.6 3.2 2.2 0.5 0.0 4.2 1.8 2.1 1.4 1.7 3.3 1.9 5.5 2.4 3.1 2.4 3.6 1.8 9.7 0.0 3.9 1.4 7.2 33.1 1.8 1.3 1.1 0.4 0.8 1.7 0.0 0.0 4.7 2.0 2.4 1.0 1.8 2.1 7.1 0.0 0.0 6.0 1.7 2.1 0.0 0.0 5.2 3.1 1.2 57.2 1.2 5.6 3.3 13.1 1.7 0.0 0.5 5.8 0.6 0.2 28.1 1.3 1.8 10.4 0.9 3.7 0.3 WDR62 "C19orf14, DKFZP434J046, FLJ33298, MCPH2" ENSG00000075702 "WD repeat domain 62" O43379 19 36054649-36105108 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 110.3;testis: 63.7;tongue: 63.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Cone photoreceptor cells: 85.5;Early spermatids: 42.5;Late spermatids: 46.2;Rod photoreceptor cells: 41.7;Spermatocytes: 67.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043255, HPA043639" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Centriolar satellite" "HPA043255: AB_2678393, HPA043639: AB_2678593" "unprognostic (1.77e-1)" "unprognostic (2.79e-3)" "unprognostic (3.16e-2)" "unprognostic (4.88e-2)" "unprognostic (1.77e-1)" "unprognostic (4.22e-3)" "unprognostic (1.78e-4)" "unprognostic (2.00e-1)" "unprognostic (4.00e-2)" "unprognostic (5.82e-3)" "unprognostic (4.72e-2)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.73e-3)" "unprognostic (2.72e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" 0.4 0.4 0.3 2.1 0.5 5.4 0.4 0.9 0.7 0.9 0.2 0.9 1.1 0.6 0.2 3.7 0.7 0.2 22.1 0.4 0.2 0.4 0.7 0.7 2.9 0.5 0.5 0.3 0.2 0.1 0.4 0.5 0.5 0.7 0.5 6.7 1.3 0.2 110.3 2.7 1.2 0.7 0.2 2.0 0.9 63.7 0.4 5.0 0.4 63.1 1.8 0.3 1.4 0.8 19.9 37.8 12.3 12.6 1.1 0.3 7.8 18.0 7.6 24.1 20.8 20.0 6.7 24.7 10.9 9.3 11.3 6.1 18.6 6.8 13.5 16.1 8.8 16.9 20.5 13.5 0.8 16.8 19.6 0.3 0.7 17.7 5.2 1.7 6.0 17.3 21.7 26.8 11.3 20.6 33.1 9.0 7.3 16.0 7.4 23.3 12.5 11.7 3.3 7.5 15.3 8.6 12.1 16.7 2.8 7.6 9.6 14.3 4.1 20.8 19.9 16.7 29.6 14.0 22.1 32.0 9.1 13.0 24.6 0.5 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.6 0.2 2.7 0.1 0.5 0.1 0.3 0.5 0.9 0.7 0.4 0.2 0.5 0.5 0.5 0.2 0.4 0.8 1.8 0.0 5.5 0.3 1.0 2.2 1.3 0.5 0.6 1.6 0.9 0.6 43.4 0.0 0.8 0.0 85.5 1.9 1.2 2.5 1.9 0.4 42.5 0.8 0.8 2.0 0.0 11.0 1.4 0.9 1.9 1.8 5.6 0.8 0.0 4.3 1.1 0.8 2.2 3.3 1.0 2.2 2.0 1.3 1.6 46.2 1.2 1.9 1.8 1.0 0.8 2.1 0.0 1.0 1.0 0.5 0.2 0.4 7.1 0.8 0.3 0.3 0.2 41.7 6.6 2.8 1.9 67.6 15.4 2.0 3.7 0.3 2.2 1.2 3.0 0.7 WSCD2 KIAA0789 ENSG00000075035 "WSC domain containing 2" Q2TBF2 12 108129288-108250537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.7;thyroid gland: 16.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.7;Excitatory neurons: 30.1;Horizontal cells: 21.9;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 9.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "RT4: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013346, HPA048133" Approved Uncertain Nucleoplasm "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA013346: AB_1858865, HPA048133: AB_2797236" "unprognostic (1.50e-1)" "unprognostic (1.64e-3)" "unprognostic (1.50e-2)" "unprognostic (4.27e-3)" "unprognostic (1.68e-1)" "unprognostic (3.43e-1)" "unprognostic (1.80e-2)" "unprognostic (3.43e-3)" "unprognostic (3.03e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-1)" "unprognostic (7.43e-2)" "unprognostic (5.99e-2)" "unprognostic (3.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.32e-3)" "unprognostic (7.62e-3)" 0.9 0.7 8.9 0.1 14.3 0.0 0.8 36.7 13.9 3.5 0.3 3.3 0.3 10.1 2.1 1.0 2.6 0.1 0.4 17.9 4.2 1.0 0.0 0.3 0.1 0.6 2.4 0.3 1.4 0.0 1.4 0.2 2.2 4.2 0.3 11.9 0.3 13.5 0.2 0.8 0.7 6.8 2.7 0.1 1.9 0.2 10.0 0.0 16.8 0.4 0.1 2.5 1.3 7.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.9 14.3 36.7 13.9 17.9 4.2 0.6 2.4 2.2 2.7 10.0 7.2 0.8 0.0 0.0 5.9 0.6 0.1 0.0 0.1 0.0 43.7 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 30.1 0.0 0.0 1.6 3.1 0.0 0.0 0.0 0.7 0.0 0.0 21.9 27.7 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 2.8 0.0 0.3 0.0 9.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 YIPF7 "FinGER9, FLJ39576" ENSG00000177752 "Yip1 domain family member 7" Q8N8F6 4 44622065-44678556 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 84.9;tongue: 27.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.6;Cardiomyocytes: 1.5;Early spermatids: 1.5;Excitatory neurons: 4.8;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.0;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA030642 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA030642: AB_10601027" "unprognostic (9.41e-4)" "unprognostic (2.27e-1)" "unprognostic (2.90e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-2)" "unprognostic (1.34e-1)" "unprognostic (9.46e-2)" "unprognostic (9.81e-2)" "unprognostic (2.32e-2)" "unprognostic (3.05e-2)" "unprognostic (1.52e-2)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.98e-2)" 0.0 0.1 1.0 0.0 1.0 0.0 0.1 5.4 1.3 0.1 0.2 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.8 1.0 1.2 0.1 0.0 0.0 0.1 0.8 1.1 0.2 0.3 0.0 0.2 0.0 1.0 0.3 0.0 0.3 0.3 0.2 84.9 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.9 0.0 0.1 27.9 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 1.0 5.4 1.3 1.0 1.2 0.8 1.1 1.0 0.9 0.9 1.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.1 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.5 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ZC3H12B "CXorf32, MCPIP2" ENSG00000102053 "Zinc finger CCCH-type containing 12B" Q5HYM0 X 65366638-65507887 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 30 "Astrocytes: 90.4;Excitatory neurons: 232.1;Inhibitory neurons: 219.8;Microglial cells: 128.4;Oligodendrocyte precursor cells: 253.8;Oligodendrocytes: 258.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000836 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "Golgi apparatus, Vesicles" "HPA000836: AB_2217374" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (1.38e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-1)" "unprognostic (7.44e-3)" "unprognostic (7.86e-3)" "unprognostic (5.46e-2)" "unprognostic (3.32e-1)" "unprognostic (5.76e-2)" "unprognostic (1.12e-3)" "unprognostic (1.28e-1)" "unprognostic (2.61e-1)" "unprognostic (1.11e-2)" "unprognostic (5.08e-2)" "unprognostic (1.45e-2)" "unprognostic (1.71e-2)" 0.6 0.5 2.4 0.4 2.7 0.2 0.5 2.1 2.7 1.3 0.8 1.3 0.6 1.3 0.5 0.3 1.3 0.6 0.6 2.7 1.6 0.7 0.5 0.5 0.5 1.1 1.4 1.7 0.4 1.6 2.2 0.0 0.9 1.1 0.6 1.9 0.6 1.1 0.2 0.3 0.9 0.9 1.3 0.4 0.8 0.2 2.1 0.9 1.0 0.3 0.3 1.0 0.9 2.3 0.1 0.2 2.1 0.3 0.0 0.0 0.2 0.5 1.1 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.0 0.3 0.5 0.0 0.0 0.3 1.5 0.7 1.2 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.4 1.7 0.0 0.0 0.9 0.2 0.8 1.2 0.4 1.0 0.1 0.4 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.2 0.0 0.5 0.0 0.0 0.4 0.7 0.2 0.3 0.4 0.7 1.3 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.4 2.7 2.1 2.7 2.7 1.6 1.1 1.4 0.9 1.3 2.1 2.3 0.2 6.4 0.5 90.4 1.3 0.0 0.5 0.0 1.2 2.7 0.1 0.6 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.7 0.0 0.2 0.2 0.7 1.3 0.5 4.2 0.0 232.1 0.2 0.2 1.4 0.0 0.1 0.0 0.6 0.7 0.7 0.1 1.7 219.8 1.3 0.0 0.0 0.3 0.2 2.5 0.0 0.0 128.4 0.1 1.0 0.0 253.8 258.0 0.2 0.6 4.1 0.3 0.3 1.0 0.4 0.0 1.5 0.0 2.1 1.1 0.0 0.1 0.1 0.4 0.0 0.4 0.5 1.0 0.1 ZCWPW2 ZCW2 ENSG00000206559 "Zinc finger CW-type and PWWP domain containing 2" Q504Y3 3 28348721-28538122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.9" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Early spermatids: 95.0;Excitatory neurons: 33.7;Inhibitory neurons: 34.9;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 31.7;Spermatocytes: 68.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035035, HPA039839" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA035035: AB_10602256, HPA039839: AB_2676708" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (4.59e-3)" "unprognostic (6.53e-2)" "unprognostic (6.09e-4)" "unprognostic (3.21e-1)" "unprognostic (2.70e-2)" "unprognostic (1.73e-3)" "unprognostic (1.12e-1)" "unprognostic (1.10e-4)" "unprognostic (1.06e-2)" "unprognostic (7.88e-2)" "unprognostic (1.40e-2)" "unprognostic (2.38e-2)" 1.5 1.7 1.8 0.9 1.5 0.8 1.8 1.6 1.9 1.4 0.2 1.4 1.2 2.1 2.1 1.3 1.0 2.0 2.7 1.7 1.1 1.6 1.2 1.3 1.2 0.8 1.0 2.4 1.9 1.5 1.2 1.2 1.0 2.2 1.1 1.6 2.3 1.1 6.2 1.9 0.9 1.0 0.8 1.1 1.8 9.9 1.2 0.6 2.5 4.5 1.0 0.8 0.8 1.6 0.3 0.2 0.8 0.3 1.2 2.8 1.2 1.1 0.8 0.3 0.3 0.2 0.9 0.7 0.5 0.6 0.8 0.4 0.2 0.2 0.3 0.4 0.4 0.3 1.1 0.3 0.6 0.5 0.6 1.2 0.5 0.3 0.5 1.3 0.5 1.5 0.3 1.0 1.5 0.3 0.2 0.6 0.3 0.1 1.1 0.3 0.3 0.6 1.2 0.1 0.3 0.9 0.2 0.4 0.7 0.8 0.4 2.6 1.0 0.8 0.4 0.7 0.6 0.3 0.2 0.3 2.8 0.5 1.0 1.0 0.7 1.1 0.3 0.7 0.2 0.1 0.3 0.2 0.3 0.2 0.5 0.7 1.0 0.2 0.2 0.4 0.3 0.2 1.8 1.5 1.6 1.9 1.7 1.1 0.8 1.0 1.0 0.8 1.2 1.6 1.6 0.0 2.0 35.6 0.4 0.6 2.7 3.7 1.2 3.0 1.6 2.7 13.6 0.0 4.3 0.0 0.0 2.4 0.1 0.4 5.9 0.5 95.0 1.2 1.2 1.0 1.2 0.0 33.7 0.9 1.4 4.3 0.0 0.6 2.5 0.8 1.4 0.5 1.3 3.3 34.9 1.9 8.2 0.6 0.7 17.7 4.7 1.3 0.0 13.1 0.7 3.7 1.0 32.2 31.7 0.6 0.3 4.9 0.3 1.1 0.6 2.6 1.7 2.0 0.0 4.4 4.5 68.7 5.8 1.1 1.6 1.2 0.6 1.3 0.7 1.3 ZKSCAN8 "LD5-1, ZNF192, ZSCAN40" ENSG00000198315 "Zinc finger with KRAB and SCAN domains 8" Q15776 6 28141883-28159460 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003483 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA003483: AB_1080686" "unprognostic (2.02e-1)" "unprognostic (1.45e-1)" "unprognostic (3.94e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.75e-3)" "unprognostic (4.19e-2)" "unprognostic (2.24e-3)" "unprognostic (5.34e-2)" "unprognostic (9.80e-3)" "unprognostic (4.68e-3)" "unprognostic (2.63e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-2)" "unprognostic (4.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.28e-1)" "unprognostic (6.33e-3)" 11.0 7.7 4.5 8.1 6.2 14.8 11.5 8.9 7.2 11.2 7.4 11.8 6.6 15.9 13.3 5.6 11.1 7.6 7.6 4.5 5.6 7.7 7.3 9.2 10.5 5.5 5.1 17.6 9.9 12.9 8.4 9.4 6.1 10.3 8.4 17.6 9.0 11.6 8.1 7.9 10.7 10.7 5.0 10.8 9.2 9.1 5.2 13.1 10.6 8.9 10.9 10.2 7.9 9.2 9.0 5.6 26.1 25.4 15.8 14.9 8.2 9.7 18.3 12.6 15.7 6.3 5.3 19.4 15.7 9.4 10.5 7.4 16.7 6.2 17.9 11.2 14.1 17.7 11.7 13.6 14.4 21.8 12.7 15.4 10.4 12.9 19.2 21.5 12.5 16.9 27.9 7.1 12.9 4.4 15.5 18.2 9.5 2.1 6.4 17.0 16.5 15.2 8.6 10.9 19.5 24.7 11.6 5.3 11.9 14.3 5.9 11.7 10.9 18.1 10.5 6.1 13.2 17.3 13.2 15.6 5.1 14.8 9.9 2.2 0.5 0.6 1.0 1.2 1.1 0.5 0.6 0.4 0.4 1.7 1.0 0.8 0.1 1.1 2.1 0.7 0.6 0.6 4.5 6.2 8.9 7.2 4.5 5.6 5.5 5.1 6.1 5.0 5.2 9.2 6.9 3.2 9.3 11.8 9.8 4.8 2.6 3.8 14.8 9.5 8.5 5.1 8.0 7.2 5.0 7.3 6.2 4.2 11.0 2.0 0.0 3.1 3.7 5.9 10.0 8.8 7.2 9.4 11.1 2.9 2.0 9.5 4.6 7.4 5.1 12.7 8.6 10.2 4.1 6.7 12.5 4.6 4.1 11.1 6.8 5.2 9.0 6.0 1.8 15.9 5.9 6.5 4.1 26.7 17.1 3.0 2.4 9.1 9.0 4.3 2.3 3.5 6.1 9.2 0.0 9.9 7.3 11.9 8.6 8.5 2.8 2.3 7.1 7.4 3.7 1.9 ZMYND15 DKFZp434N127 ENSG00000141497 "Zinc finger MYND-type containing 15" Q9H091 17 4739833-4746119 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 28.3" "Cell type enriched" "Detected in many" 6 "Early spermatids: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.1;CAPAN-2: 1.9;HaCaT: 1.6;T-47d: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA023286 Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear speckles" Cytosol "HPA023286: AB_1859076" "unprognostic (2.30e-3)" "unprognostic (1.63e-2)" "unprognostic (1.61e-2)" "unprognostic (7.49e-3)" "unprognostic (3.62e-2)" "unprognostic (7.86e-2)" "unprognostic (4.97e-2)" "unprognostic (1.59e-2)" "unprognostic (1.33e-2)" "unprognostic (3.49e-1)" "unprognostic (6.72e-3)" "unprognostic (4.02e-1)" "unprognostic (5.47e-2)" "unprognostic (4.62e-2)" "unprognostic (9.24e-3)" "unprognostic (2.69e-1)" "unprognostic (2.07e-1)" 1.8 1.3 1.6 2.4 1.6 1.0 1.7 1.6 2.5 0.9 1.7 0.8 4.0 0.6 0.5 0.9 1.1 2.8 0.6 1.6 1.8 1.9 3.1 4.6 1.7 2.4 2.0 0.7 1.2 5.5 1.4 1.2 2.0 1.7 0.7 0.3 3.1 0.8 0.4 1.4 3.0 0.7 2.0 5.5 1.9 28.3 2.4 0.8 1.1 0.1 0.4 1.8 0.7 2.6 2.1 0.3 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.5 1.1 0.9 1.9 0.0 0.0 0.0 0.2 1.6 0.4 0.1 0.0 0.2 0.7 0.0 0.2 0.5 0.3 0.0 0.6 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.2 0.2 0.0 0.0 0.6 0.6 0.9 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.6 1.6 1.6 2.5 1.6 1.8 2.4 2.0 2.0 2.0 2.4 2.6 0.8 0.0 2.0 1.3 0.6 0.9 8.0 1.8 0.6 0.3 4.4 3.7 0.7 2.8 3.1 1.8 0.0 0.1 0.2 3.3 0.0 1.6 191.4 2.8 0.3 1.4 1.2 0.0 0.0 3.9 0.0 0.7 4.6 2.7 0.0 0.3 3.9 0.6 5.2 0.0 0.1 2.9 0.0 11.9 7.3 30.9 0.6 12.9 1.8 1.9 21.9 2.0 0.0 1.0 0.5 3.5 1.4 2.2 0.1 6.7 3.8 0.8 3.7 0.3 0.0 0.2 1.0 24.3 2.0 0.5 0.9 0.0 0.2 0.3 1.3 8.5 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF426 MGC2663 ENSG00000130818 "Zinc finger protein 426" Q9BUY5 19 9523223-9538645 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029342 Approved Approved Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029342: AB_10603007" "unprognostic (3.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-2)" "unprognostic (6.62e-2)" "prognostic favorable (3.74e-4)" "unprognostic (4.34e-2)" "unprognostic (1.77e-2)" "unprognostic (4.75e-3)" "unprognostic (1.05e-3)" "unprognostic (8.89e-3)" "unprognostic (7.41e-3)" "prognostic favorable (2.57e-6)" "unprognostic (1.05e-1)" "unprognostic (3.17e-2)" "unprognostic (2.49e-1)" "prognostic favorable (1.81e-4)" 5.1 3.3 3.1 3.9 4.0 5.7 6.9 5.4 3.4 5.5 4.9 4.1 2.8 7.6 4.5 20.6 5.8 4.3 5.4 3.2 2.9 4.3 2.2 5.1 4.1 3.4 3.4 9.2 4.3 6.3 2.4 5.6 3.4 5.9 3.8 5.1 4.0 5.3 3.7 4.1 2.9 7.8 2.9 4.7 3.7 4.8 3.8 5.7 6.7 5.5 5.7 4.7 5.8 6.0 5.7 1.8 11.2 11.8 7.4 9.7 6.2 7.1 10.8 9.4 11.4 2.4 2.5 5.7 5.6 6.9 6.6 4.8 11.7 8.4 14.0 2.7 9.0 23.7 9.5 4.3 6.7 0.7 7.4 12.4 7.1 10.5 15.0 10.2 10.2 9.7 9.6 0.5 9.1 0.3 13.7 11.4 14.0 1.3 4.4 7.4 13.9 5.9 5.1 14.7 6.3 8.5 12.1 4.3 9.7 9.5 6.0 5.5 8.3 13.2 7.7 6.0 7.7 6.4 9.7 4.8 1.9 0.3 9.6 10.0 3.2 6.1 8.8 4.5 7.8 7.6 6.8 8.7 3.8 6.5 10.0 9.3 6.7 7.8 6.3 3.4 7.1 3.4 3.1 4.0 5.4 3.4 3.2 2.9 3.4 3.4 3.4 2.9 3.8 6.0 15.0 28.9 26.5 3.3 13.2 3.4 15.6 3.2 12.5 24.8 17.1 14.6 10.1 5.7 12.4 7.3 20.9 12.8 13.4 3.8 21.5 10.9 33.5 11.5 14.2 16.4 3.6 12.6 5.4 4.2 10.2 12.4 5.1 15.5 28.4 22.4 14.3 3.0 7.6 37.0 3.9 4.2 12.2 8.9 1.6 8.2 17.1 8.2 3.6 5.6 11.2 20.1 15.5 4.5 4.7 6.9 5.1 22.2 6.7 13.3 4.7 5.4 14.6 22.0 6.6 17.9 13.2 12.2 11.8 14.7 2.8 14.2 12.1 12.3 6.3 17.9 ZNF529 KIAA1615 ENSG00000186020 "Zinc finger protein 529" Q6P280 19 36534774-36605276 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.6;Horizontal cells: 75.7;Inhibitory neurons: 45.7;Oligodendrocytes: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA031311 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA031311: AB_10604158" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (8.51e-2)" "unprognostic (7.94e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-3)" "unprognostic (8.67e-2)" "unprognostic (1.30e-2)" "unprognostic (3.84e-3)" "unprognostic (7.10e-2)" "unprognostic (1.05e-3)" "unprognostic (6.61e-3)" "unprognostic (3.37e-2)" "unprognostic (1.45e-2)" "unprognostic (1.00e-1)" "unprognostic (9.64e-2)" "prognostic favorable (1.39e-5)" 5.7 5.8 8.1 5.1 11.5 10.1 6.0 9.6 10.4 6.2 6.5 5.1 3.1 6.9 5.5 3.3 8.0 3.8 7.3 7.1 9.8 5.9 4.4 5.8 7.4 8.9 9.5 8.9 3.6 6.0 5.7 4.8 9.8 5.1 3.0 20.1 4.2 3.4 5.4 6.6 5.1 4.5 9.0 6.0 3.9 9.2 9.1 6.3 5.7 5.5 6.4 4.7 5.2 14.9 4.0 8.1 11.5 12.3 5.4 6.6 4.5 6.1 3.3 3.4 8.6 4.1 3.1 10.7 7.7 4.9 4.4 1.5 8.7 3.9 6.2 14.4 9.7 13.1 7.6 3.0 6.4 9.9 7.9 8.0 5.0 4.6 6.7 5.8 2.9 8.1 5.5 0.7 7.1 1.1 10.0 3.4 7.5 0.2 3.3 2.9 6.9 4.9 3.0 10.6 5.1 10.4 8.5 2.7 2.6 4.4 3.5 6.0 7.0 7.4 5.3 6.1 7.6 13.2 8.5 9.0 0.2 3.3 5.7 4.7 1.1 1.5 2.3 0.6 3.1 2.9 2.5 2.4 1.2 2.2 2.8 2.2 0.5 2.1 0.7 1.4 3.1 1.2 8.1 11.5 9.6 10.4 7.1 9.8 8.9 9.5 9.8 9.0 9.1 14.9 10.0 3.2 3.3 23.8 14.1 9.8 5.3 2.9 10.2 19.0 12.3 8.1 14.7 5.7 5.7 7.3 25.0 3.6 11.0 1.4 5.9 3.5 4.5 10.1 8.0 10.0 3.0 14.1 46.6 1.6 2.8 7.9 5.1 9.9 2.5 15.2 7.9 6.9 4.0 75.7 45.7 3.5 4.1 5.1 8.4 2.3 6.5 4.3 5.4 19.7 3.1 7.8 6.2 36.2 61.5 2.2 2.5 6.8 7.2 7.0 1.4 4.5 8.8 22.4 0.0 9.1 7.5 18.0 10.3 8.2 9.1 3.3 11.2 9.9 2.8 6.5 ZNF589 SZF1 ENSG00000164048 "Zinc finger protein 589" Q86UQ0 3 48241100-48299253 "Predicted intracellular proteins, Transcription factors" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9" "Cancer enhanced" "Detected in all" "testis cancer: 15.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HAP1: 44.1;NTERA-2: 71.1" HPA003145 Uncertain Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA003145: AB_1080738" "unprognostic (2.49e-3)" "prognostic favorable (2.50e-4)" "unprognostic (9.14e-2)" "unprognostic (7.34e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.01e-5)" "prognostic favorable (6.45e-5)" "unprognostic (2.64e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.21e-4)" "unprognostic (8.02e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-2)" "unprognostic (3.45e-2)" "unprognostic (9.57e-3)" "unprognostic (2.19e-2)" 7.2 8.5 9.6 6.7 9.7 5.8 6.9 14.9 11.2 11.2 2.3 8.3 3.8 7.6 20.1 10.2 8.8 4.6 6.2 11.0 9.3 7.1 3.7 10.1 12.3 7.9 7.9 13.6 6.5 5.9 7.8 3.0 7.7 18.3 6.6 14.8 6.6 15.7 6.1 9.8 16.1 6.0 7.2 24.1 7.9 6.6 8.9 8.1 16.6 4.2 12.2 8.5 10.7 10.2 4.5 3.2 12.7 10.8 15.8 8.7 16.1 4.6 3.5 5.2 6.9 6.8 6.0 17.8 3.3 4.7 4.0 3.9 44.1 11.2 4.2 11.5 10.5 22.5 14.9 5.4 2.9 5.4 5.6 2.8 7.5 6.4 4.3 5.7 9.0 13.7 15.4 4.5 2.8 4.5 6.8 4.1 71.1 4.3 6.6 3.3 4.6 6.8 4.0 4.4 4.9 9.1 3.4 3.7 13.7 18.8 6.0 8.0 14.0 3.0 5.8 7.2 3.5 8.9 12.0 14.6 4.0 12.6 9.3 1.2 2.2 1.6 2.8 2.0 3.5 3.1 3.4 3.8 2.3 1.9 3.8 3.8 1.2 1.2 2.8 10.9 3.1 1.9 9.6 9.7 14.9 11.2 11.0 9.3 7.9 7.9 7.7 7.2 8.9 10.2 2.0 0.0 5.4 4.2 5.5 1.1 1.4 0.9 3.4 15.3 2.4 1.5 4.1 0.0 2.8 9.2 20.9 2.2 13.7 1.3 3.9 1.4 1.5 7.3 3.5 2.7 1.8 2.1 9.8 1.0 1.2 4.3 1.5 11.7 0.0 3.9 2.5 1.0 3.3 1.7 11.5 2.5 0.0 5.5 3.0 2.0 2.1 7.3 1.8 3.7 3.7 5.3 1.0 9.5 11.0 1.0 1.7 4.5 5.3 1.5 1.4 1.6 2.4 13.1 6.6 4.1 3.0 1.4 3.1 2.9 1.3 0.0 4.4 7.0 2.5 0.9 ZNF649 FLJ12644 ENSG00000198093 "Zinc finger protein 649" Q9BS31 19 51889235-51905040 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 29.1" "Low region specificity" "Detected in all" HPA026541 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "HPA026541: AB_1859390" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (8.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.15e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-1)" "unprognostic (4.23e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (2.24e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "prognostic favorable (4.60e-5)" "unprognostic (3.91e-2)" "unprognostic (2.09e-1)" "unprognostic (3.07e-2)" "unprognostic (1.41e-2)" 5.7 4.7 5.6 5.2 6.0 6.5 10.1 9.1 7.8 5.4 1.2 5.6 4.1 8.6 7.0 6.5 7.2 5.6 6.5 5.6 9.2 6.3 4.6 5.6 7.9 7.8 5.2 9.9 6.0 9.5 3.3 8.9 6.1 21.2 6.0 12.8 4.9 7.1 4.0 8.1 4.3 7.6 4.1 6.5 5.5 7.9 6.5 7.9 8.2 6.9 6.4 6.8 3.8 13.8 4.1 0.6 18.3 13.4 7.1 5.7 0.8 7.7 5.4 7.8 7.2 3.5 3.2 3.9 1.8 5.9 5.4 5.6 9.4 7.4 7.3 1.8 22.5 18.4 1.7 4.3 5.5 5.9 8.2 7.1 5.1 9.9 3.3 6.0 4.7 1.0 4.4 0.2 6.6 1.2 16.1 8.2 29.1 0.1 1.7 9.5 10.1 6.6 7.3 15.2 8.2 8.4 9.4 4.8 6.1 10.0 5.9 8.1 3.6 7.0 6.7 2.7 9.5 5.2 0.7 4.9 2.6 1.6 15.3 3.1 4.4 7.7 6.0 4.6 11.6 4.8 7.2 6.7 5.6 9.1 7.4 5.5 1.6 7.7 4.3 4.5 10.1 4.2 5.6 6.0 9.1 7.8 5.6 9.2 7.8 5.2 6.1 4.1 6.5 13.8 5.1 0.0 3.2 0.3 5.9 6.5 10.6 4.2 1.8 8.0 5.4 6.5 5.5 10.0 3.0 3.7 0.0 6.2 4.1 2.5 13.7 5.3 1.2 2.7 6.1 5.6 3.0 6.9 2.0 2.4 7.1 6.1 5.6 3.5 12.0 7.3 5.3 2.9 4.1 15.2 2.2 3.7 0.0 3.5 3.3 1.5 5.3 3.4 5.4 1.9 1.9 6.8 7.2 4.0 6.1 3.5 1.0 9.1 2.4 7.2 1.2 3.8 0.5 6.2 6.6 7.2 5.7 4.4 3.3 4.9 8.1 7.0 3.4 4.1 2.6 8.4 ZNF670 MGC12466 ENSG00000277462 "Zinc finger protein 670" Q9BS34 1 247034637-247078811 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA003142 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA003142: AB_1859404" "unprognostic (2.11e-1)" "unprognostic (8.04e-3)" "unprognostic (2.05e-3)" "unprognostic (9.98e-2)" "unprognostic (1.27e-1)" "unprognostic (3.76e-1)" "unprognostic (1.26e-2)" "unprognostic (1.50e-2)" "unprognostic (1.63e-2)" "unprognostic (3.23e-2)" "unprognostic (9.88e-2)" "unprognostic (5.21e-3)" "unprognostic (2.19e-2)" "unprognostic (1.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.95e-1)" "unprognostic (1.39e-2)" 2.2 1.5 0.8 1.1 0.9 0.5 2.3 2.8 1.2 1.5 0.3 1.5 1.0 2.3 0.6 1.2 1.6 1.3 1.1 0.9 0.8 1.7 1.7 1.5 1.5 0.5 0.8 2.1 1.8 1.6 1.0 0.7 0.5 1.3 1.3 2.1 1.5 1.1 1.0 1.5 1.5 1.7 0.5 1.4 2.0 2.3 0.9 1.9 1.4 1.4 1.7 1.7 1.5 0.8 2.7 1.7 5.7 6.9 1.3 1.9 12.0 3.1 2.0 3.7 3.6 2.4 2.5 4.5 6.2 1.9 2.2 2.1 6.3 2.4 6.8 3.1 0.7 4.1 1.4 3.4 1.1 4.6 2.6 1.2 2.5 2.3 4.9 0.6 2.4 3.8 5.4 1.9 3.9 1.1 5.7 2.4 9.8 5.5 3.6 5.7 7.5 3.9 2.2 5.7 6.7 5.4 4.5 1.8 2.6 3.0 1.9 9.3 1.7 2.5 2.4 1.8 3.6 3.8 6.8 8.0 0.9 3.4 3.0 0.0 0.6 0.5 1.2 0.7 0.6 2.1 1.1 1.3 1.3 1.5 1.8 1.3 0.3 1.0 0.4 0.7 0.9 0.6 0.8 0.9 2.8 1.2 0.9 0.8 0.5 0.8 0.5 0.5 0.9 0.8 4.2 3.2 1.7 0.0 2.5 24.2 9.3 6.1 3.4 4.1 5.0 4.8 0.9 4.3 5.1 5.5 0.0 2.3 2.7 0.4 5.9 5.2 8.9 11.9 2.6 5.2 0.0 3.8 0.0 2.9 8.3 6.3 1.5 13.4 0.0 2.0 5.7 2.9 2.5 6.7 0.0 1.8 8.2 1.6 10.2 2.0 1.8 1.5 7.2 0.0 2.0 3.0 1.0 0.0 0.0 3.5 1.8 1.5 0.9 5.2 1.0 3.6 4.7 1.5 0.0 9.3 4.0 3.2 4.0 2.3 11.2 0.8 1.4 2.2 1.8 3.6 ZNF789 ENSG00000198556 "Zinc finger protein 789" Q5FWF6 7 99472890-99503650 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029500, HPA050793" Uncertain Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA029500: AB_10603009, HPA050793: AB_2681240" "unprognostic (6.84e-3)" "unprognostic (5.75e-2)" "unprognostic (5.71e-2)" "unprognostic (2.49e-2)" "unprognostic (3.08e-1)" "unprognostic (2.90e-2)" "unprognostic (1.25e-3)" "unprognostic (4.38e-3)" "unprognostic (5.16e-2)" "unprognostic (1.56e-1)" "prognostic favorable (7.14e-4)" "unprognostic (1.58e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (6.63e-2)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" "prognostic favorable (5.31e-6)" 5.2 5.7 8.2 4.7 8.3 7.6 5.5 11.0 9.9 7.7 8.1 8.7 8.5 6.1 7.2 5.0 7.1 2.6 4.6 8.3 8.7 9.8 8.8 4.9 6.2 8.4 8.7 7.9 7.6 3.3 11.8 2.6 8.8 16.4 7.3 11.7 6.1 4.3 5.7 7.3 9.8 3.7 8.0 10.7 6.1 13.4 8.5 4.5 8.4 2.9 5.8 5.1 5.2 9.2 12.0 3.8 6.1 11.0 1.9 1.8 8.4 5.8 2.2 3.7 7.9 6.0 7.7 8.6 4.8 2.7 3.7 5.0 3.2 3.3 5.0 4.0 6.0 6.6 10.3 11.8 3.1 4.3 14.5 2.1 2.8 7.2 3.5 2.2 3.9 11.1 10.2 7.7 3.3 11.6 5.7 12.0 6.1 5.7 5.6 7.0 6.2 9.4 4.9 3.4 5.9 6.6 4.2 11.8 7.3 3.4 3.0 7.5 6.1 6.4 8.0 9.9 5.9 5.0 7.6 11.9 10.8 8.2 6.9 2.0 1.5 1.5 2.3 1.0 2.7 2.3 3.0 2.6 5.2 3.6 6.0 3.7 0.3 4.2 1.3 13.5 5.1 1.8 8.2 8.3 11.0 9.9 8.3 8.7 8.4 8.7 8.8 8.0 8.5 9.2 8.2 0.0 6.3 11.8 9.5 5.5 4.2 4.0 4.6 18.3 6.3 6.7 2.4 1.5 4.6 1.8 14.6 4.4 14.0 6.3 1.9 3.8 33.9 5.2 4.8 7.2 5.4 8.6 10.4 5.4 3.2 4.7 9.2 5.6 3.8 11.8 1.8 3.5 6.9 6.7 12.7 6.3 4.1 3.1 6.5 8.4 3.4 4.6 7.2 10.3 3.8 12.0 5.2 12.5 10.6 4.3 5.4 4.5 6.1 2.7 5.2 4.6 4.9 14.7 0.0 6.5 4.8 20.8 4.8 6.7 5.3 2.2 6.9 8.5 6.6 3.4 ZNF853 DKFZp434J1015 ENSG00000236609 "Zinc finger protein 853" P0CG23 7 6615610-6624290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.2;Granulosa cells: 15.1;Muller glia cells: 13.2;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 20.1;SH-SY5Y: 29.5;U-2 OS: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067690 Approved Approved Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA067690: AB_2685888" "unprognostic (1.35e-3)" "unprognostic (2.63e-1)" "unprognostic (7.17e-2)" "unprognostic (8.77e-2)" "unprognostic (2.76e-1)" "unprognostic (1.96e-1)" "unprognostic (1.17e-1)" "unprognostic (3.54e-1)" "unprognostic (2.26e-2)" "unprognostic (5.06e-2)" "unprognostic (1.87e-3)" "unprognostic (9.28e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.41e-3)" "unprognostic (4.95e-2)" "unprognostic (2.30e-3)" "unprognostic (4.01e-2)" 4.1 2.8 24.8 2.3 24.7 0.6 4.5 20.4 24.0 9.6 11.8 12.9 1.1 11.3 4.4 4.3 9.2 4.5 10.5 23.7 23.7 4.9 0.5 3.7 2.9 27.8 27.9 12.0 7.0 5.5 6.6 2.8 25.1 7.8 1.7 5.1 5.4 8.6 27.1 3.1 4.4 6.6 25.6 3.5 4.9 2.6 24.8 3.3 7.9 20.2 2.0 10.1 4.9 21.0 0.0 1.6 4.7 20.1 0.2 0.0 0.2 0.4 0.0 2.1 0.4 3.6 0.8 0.0 7.8 0.0 0.7 0.0 7.2 0.2 2.0 0.0 2.6 0.6 0.0 3.8 2.8 0.0 0.1 0.7 0.6 0.2 0.1 2.0 0.0 1.6 3.2 0.1 1.3 0.1 0.5 2.7 7.5 0.0 0.0 2.3 7.8 0.1 1.5 7.6 6.3 29.5 0.0 0.3 1.2 3.9 1.1 4.3 0.0 1.5 19.5 0.0 1.9 0.4 0.1 0.1 0.0 0.0 7.8 0.0 0.0 0.8 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 24.8 24.7 20.4 24.0 23.7 23.7 27.8 27.9 25.1 25.6 24.8 21.0 4.3 0.0 0.0 2.0 1.0 0.5 1.5 0.2 1.2 13.2 3.2 4.4 10.4 0.0 0.6 7.3 6.2 0.0 2.0 0.1 0.0 0.6 1.6 7.5 4.3 3.2 1.8 0.4 1.5 0.7 0.0 4.4 0.5 2.3 0.0 15.1 2.5 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.9 2.4 5.3 0.2 3.6 1.9 0.1 13.2 1.0 2.0 2.8 0.4 0.1 8.6 1.3 3.3 0.0 0.2 2.3 10.4 13.1 6.4 5.4 0.5 0.5 0.4 0.3 0.3 1.8 6.9 0.1 0.7 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999024-75110994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;T-reg: 2.4" "Group enriched" "Detected in many" 4 "granulocytes: 2.4;T-cells: 2.4" "Cell line enhanced" "Detected in all" "HMC-1: 176.9;MOLT-4: 134.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favorable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 18.7 16.5 21.1 9.6 22.3 6.7 17.8 9.1 22.8 25.3 19.0 30.6 9.6 22.5 9.5 65.9 18.0 7.5 21.0 23.4 24.5 14.7 17.6 24.1 7.7 19.6 22.5 17.4 11.5 11.8 13.4 11.2 18.6 13.7 12.1 7.4 16.9 7.0 81.2 25.0 15.3 11.4 13.4 4.5 21.0 37.4 30.7 53.2 29.3 30.6 13.3 22.5 26.4 17.5 10.9 15.7 26.7 27.5 27.7 21.4 91.2 13.0 18.3 17.5 17.1 25.4 33.2 2.9 9.9 28.3 16.8 25.5 13.0 17.8 13.9 26.7 7.5 56.7 4.8 47.0 22.0 27.5 176.9 19.5 14.7 18.4 14.9 30.8 29.0 68.3 27.8 8.8 13.7 104.5 134.6 100.6 37.1 31.4 16.7 59.0 10.0 17.4 25.1 30.5 35.4 37.7 20.7 27.0 8.3 21.7 71.6 25.8 19.9 12.0 21.0 21.5 7.9 50.5 55.1 31.6 15.8 30.2 12.6 2.4 0.5 0.4 0.0 0.5 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.5 0.0 2.4 0.1 21.1 22.3 9.1 22.8 23.4 24.5 19.6 22.5 18.6 13.4 30.7 17.5 34.8 9.6 14.4 16.6 1.8 15.9 16.0 11.2 4.6 12.6 24.3 22.4 16.4 18.6 14.0 3.7 52.1 6.4 2.3 25.5 0.0 8.9 25.9 30.7 15.1 30.2 19.8 30.5 45.2 12.7 10.1 15.1 18.3 28.0 36.8 23.7 12.8 14.4 10.4 3.3 42.4 14.0 14.2 7.3 10.9 16.3 6.8 7.3 14.2 33.7 7.6 15.0 0.0 33.7 29.5 20.0 12.1 4.1 1.8 17.2 9.6 6.2 15.1 6.5 0.0 12.4 14.7 13.6 18.7 21.0 19.6 4.5 13.3 16.7 12.7 29.6